CN108341799B - 用于治疗癌症、病毒感染和肺病的新型吲哚衍生物 - Google Patents

用于治疗癌症、病毒感染和肺病的新型吲哚衍生物 Download PDF

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CN108341799B
CN108341799B CN201810021544.4A CN201810021544A CN108341799B CN 108341799 B CN108341799 B CN 108341799B CN 201810021544 A CN201810021544 A CN 201810021544A CN 108341799 B CN108341799 B CN 108341799B
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indol
bromo
acrylonitrile
pyridin
cyanovinyl
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CN108341799A (zh
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C.博格雷特
C.吉洛
J.鲁利奥
J.里沃利尔
D.卡尼托
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Centre National de la Recherche Scientifique CNRS
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201810021544.4A 2012-12-07 2013-12-06 用于治疗癌症、病毒感染和肺病的新型吲哚衍生物 Active CN108341799B (zh)

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US201261734451P 2012-12-07 2012-12-07
EP12306536.9 2012-12-07
EP12306536 2012-12-07
US61/734,451 2012-12-07
EP13157372 2013-03-01
EP13157372.7 2013-03-01
CN201380063540.8A CN104854088B (zh) 2012-12-07 2013-12-06 用于治疗癌症、病毒感染和肺病的新型吲哚衍生物

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CN201380063540.8A Active CN104854088B (zh) 2012-12-07 2013-12-06 用于治疗癌症、病毒感染和肺病的新型吲哚衍生物

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EP2928864B1 (en) 2012-12-07 2020-01-15 Biokinesis New derivatives of indole for the treatment of cancer, viral infections and lung diseases
US10624876B2 (en) * 2016-10-24 2020-04-21 Biokinesis Derivatives of indole for the treatment of endometriosis
CN114072403A (zh) * 2019-05-07 2022-02-18 百时美施贵宝公司 前药化合物
CN119451970A (zh) * 2022-06-27 2025-02-14 埃维克斯塔生物公司 用于治疗癌症的n-取代的吲哚衍生物及其偶联物
JP2026504659A (ja) 2022-12-05 2026-02-06 センター ナショナル デ ラ レシェルシェ サイエンティフィーク 癌及び感染症の治療のためのインドールの誘導体
WO2024126771A1 (en) 2022-12-16 2024-06-20 Evexta Bio Process for preparing (z)-3-(2-(5-bromo-1h-indol-3-yl)-2-cyanovinyl)-4-methoxybenzonitrile

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US9643923B2 (en) 2017-05-09
US10851054B2 (en) 2020-12-01
PL2928864T3 (pl) 2020-06-15
HK1210607A1 (en) 2016-04-29
EP2928864B1 (en) 2020-01-15
IL238722A0 (en) 2015-06-30
US20170233342A1 (en) 2017-08-17
US20150307450A1 (en) 2015-10-29
CA2891900C (en) 2021-07-06
US10189782B2 (en) 2019-01-29
CA2891900A1 (en) 2014-06-12
KR20150092301A (ko) 2015-08-12
JP2016501254A (ja) 2016-01-18
CN104854088B (zh) 2018-02-16
IL238722B (en) 2018-10-31
CN108341799A (zh) 2018-07-31
JP6250062B2 (ja) 2017-12-20
KR102169940B1 (ko) 2020-10-26
EP2928864A1 (en) 2015-10-14
CN104854088A (zh) 2015-08-19

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