CN108324587A - A kind of anti-ageing smoothing wrinkle composition - Google Patents

A kind of anti-ageing smoothing wrinkle composition Download PDF

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Publication number
CN108324587A
CN108324587A CN201810351276.2A CN201810351276A CN108324587A CN 108324587 A CN108324587 A CN 108324587A CN 201810351276 A CN201810351276 A CN 201810351276A CN 108324587 A CN108324587 A CN 108324587A
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China
Prior art keywords
composition
firm
ageing
antioxidant
renovation agent
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Application number
CN201810351276.2A
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Chinese (zh)
Inventor
不公告发明人
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Foshan Harvest Chemical Technology Co Ltd
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Foshan Harvest Chemical Technology Co Ltd
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Priority to CN201810351276.2A priority Critical patent/CN108324587A/en
Publication of CN108324587A publication Critical patent/CN108324587A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of anti-ageing smoothing wrinkle compositions, include the ingredient of moisturizer, antioxidant, Firm renovation agent, and wherein antioxidant includes one or more of in sea cucumber gum former peptide, Purslane extract, vitamin E and its derivative;It is one or more of in Firm renovation agent including collagen, epidermal growth factor, left-handed C stostes, ginseng extract.Composition addition antioxidant can effectively remove free radical, reduce oxidative damage, play antiaging effect;Addition moisturizer can maintain skin moisture, improve elasticity of skin, play the role of anti-ageing smoothing wrinkle indirectly;Addition Firm renovation agent can promote skin collagen synthesis, delay skin aging;Effect enables composition to play better anti-ageing wrinkle removing effect between ingredient, and composition is applied can assign cosmetics good anti-ageing wrinkle improvement effect in cosmetics.

Description

A kind of anti-ageing smoothing wrinkle composition
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of anti-ageing smoothing wrinkle composition.
Background technology
People cause skin fold occur due to social concerns such as the growth at age, the pressure of work, and the age is bigger, Wrinkle, aging are with regard to increasingly severe.And in order to which beautiful appearance is resident, it is necessary to skin care, realize anti-ageing smoothing wrinkle.And With the continuous improvement of people's living standards, people pursue, healthy, the hope of youth beautiful appearance is also increasingly stronger.However Aging is the inexorable law in any life process, is biology rule independent of man's will, but delaying senility speed Degree, reducing the appearance of wrinkle can be reached by approach such as conditioning, cosmetic skins.
Water laser accunputure is current popular anti-aging means, and safety is controversial.Some consumers to like to be beautiful are The effect for pursuing instant apparent anti-aging, carries out beauty in this way.So-called water laser accunputure or water laser accunputure skill Art refers to that the medicine skin makeup nutritional ingredient such as hyaluronic acid, hEGF and creotoxin is injected skin corium by instrument and equipment, after injection Skin-tightening is pale, full water profit.Though water laser accunputure can remold the smooth flexible skin that compacts, band in a short time The side effect come is also apparent.Water laser accunputure is subcutaneously injected, and micro-shaping medical and beauty treatment is belonged to, and effect & Safety is non- It is often limited by medical condition, risk is larger.Therefore, the eager demand one kind of people seeking beauty it is safer, effectively and easily resist Aging mode.
Invention content
The purpose of the present invention is to provide a kind of anti-ageing smoothing wrinkle compositions, can increase skin moisture, promote skin collagen egg White synthesis, delay skin aging play the role of anti-ageing smoothing wrinkle.
In order to achieve the above object, the present invention provides the following technical solution:
A kind of anti-ageing smoothing wrinkle composition, includes the component of following mass parts:
Moisturizer 10~18
Antioxidant 3~8
Firm renovation agent 5~11
Wherein, antioxidant include one kind in sea cucumber gum former peptide, Purslane extract, vitamin E and its derivative or More than;
Firm renovation agent including collagen, epidermal growth factor, left-handed C stostes, one kind in ginseng extract or with On.
Further, the composition includes the component of following mass parts:
Moisturizer 12~16
Antioxidant 4~6
Firm renovation agent 7~9
Wherein, antioxidant include one kind in sea cucumber gum former peptide, Purslane extract, vitamin E and its derivative or More than;
Firm renovation agent including collagen, epidermal growth factor, left-handed C stostes, one kind in ginseng extract or with On.
Further, the composition includes the component of following mass parts:
Moisturizer 14
Antioxidant 5
Firm renovation agent 8
Wherein, antioxidant include one kind in sea cucumber gum former peptide, Purslane extract, vitamin E and its derivative or More than;
Firm renovation agent including collagen, epidermal growth factor, left-handed C stostes, one kind in ginseng extract or with On.
In addition, in the Firm renovation agent including collagen, epidermal growth factor, left-handed C stostes, ginseng extract It is one or more of;
The moisturizer include rose, small molecule sodium hyaluronate, glucan, glycerine, one kind in glycine betaine or with On.
Composition of the present invention can be used for cosmetics, such as can be used as additive for anti-ageing, smoothing wrinkle class cosmetics.
Compared with prior art, the device have the advantages that it is as follows:
The composition addition antioxidant of the present invention can effectively remove free radical, oxidative damage be reduced, such as sea cucumber gum former peptide Ultra-oxygen anion free radical and hydroxyl radical free radical are effectively removed, Purslane extract can improve superoxide dismutase activity, Free radical and lipid peroxidation confrontation body injury are reduced or eliminated, antioxidation is effectively played, to play the work of anti-aging With;Addition moisturizer can maintain skin moisture, improve elasticity of skin, play the role of anti-ageing smoothing wrinkle indirectly, such as rose energy Skin is penetrated into, deep water supplement makes cell expansion, and then can reduce wrinkle;Addition Firm renovation agent can promote skin collagen Synthesis, delay skin aging promote skin tissue's metabolism, further function as anti-ageing if epidermal growth factor repairs epidermal tissue The effect of smoothing wrinkle;Effect enables composition to play better anti-ageing wrinkle removing effect between ingredient, and composition is applied and is being made up It can assign cosmetics good anti-aging effects in product, wrinkle can be effectively reduced, enable skin more pale, fine and smooth, flexible.
Specific implementation mode
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
3 grams of sea cucumber gum former peptides, 5 grams of epidermal growth factor, 10 grams of roses and 82 grams of deionized waters are placed in mixer In, it is uniformly mixed, you can obtain anti-ageing smoothing wrinkle composition 1.
Embodiment 2
5 grams of Purslane extracts, 8 grams of left-handed C stostes, 14 grams of small molecule sodium hyaluronates and 73 grams of deionized waters are placed in mixing It in device, is uniformly mixed, you can obtain anti-ageing smoothing wrinkle composition 2.
Embodiment 3
8 grams of vitamin Es and its derivative, 11 grams of ginseng extracts, 18 grams of glycine betaines and 63 grams of deionized waters are placed in mixed It in clutch, is uniformly mixed, you can obtain anti-ageing smoothing wrinkle composition 3.
Anti-aging is tested
Experimental animal:It is 18~22g to take the kunming mice 60 of health, weight, is randomly divided into 3 groups, every group of 20 mouse, Anti-ageing smoothing wrinkle composition prepared by Examples 1 to 3 is smeared respectively.
Experimental method:Each group mouse carries out back depilation with 0.8% sodium sulphate, leaks the test section of 4cm × 4cm cruelly.It applies Smear and first clean skin with warm water before composition, the mouse for being coated with composition is placed on 1h in sunlight simulated experiment case, continuously into During which row 3 months shaves off the mouse hair newly grown in time.Finally, clip mouse test section skin prepares skin histology homogenate, With superoxide dismutase (SOD) vigor in kit measurement mouse skin and malonaldehyde (MDA) content.Experimental result is seen below Table 1:
Table 1
Group SOD(U/mg) MDA(U/mg)
Blank group 116.5±10.3 4.3±0.8
Embodiment 1 165.6±8.5 2.1±0.3
Embodiment 2 168.4±7.9 1.9±0.8
Embodiment 3 173.8±10.1 2.2±0.6
As can be seen from Table 1 the embodiment of the present invention 1~3 prepare composition increase reducing agent SOD content and The content for reducing oxidation product MDA illustrates that the present composition has excellent activity of fighting against senium.
Embodiment 4
A kind of preparation method of anti-ageing smoothing wrinkle lotion is as follows:According to mass percent, by 3% glycerine, 0.4% xanthans, The smooth stearate of 2% sorb, 3% sucrose cocounut oil acid esters and 70.2% deionized water, which are mixed evenly, is heated to 85 DEG C to obtain the final product 9% caprylic/capric triglyceride, 4% white oil and 2% stearyl alcohol are mixed evenly heating and are heated to 85 DEG C to obtain the final product by water phase Gained oil phase is continued to stir under vacuum, water phase is then added into oil phase by oil phase, and is continued to stir and be emulsified, breast After change, continue insulated and stirred 15min, lemon acid for adjusting pH is added after being cooled to 40 DEG C to neutrality, adds 0.2% benzene oxygen second Alcohol, 6% anti-ageing smoothing wrinkle composition, 1 and 0.2% essence, stir.
Embodiment 5
A kind of preparation method of anti-ageing anti-wrinkle cream is as follows:According to mass percent, by 10% caprylic/capric triglyceride, 1% cetostearyl alcohol, 2% dicetyl phosphate, 2.5% white oil and 1% cyclic silicone oils heating stirring are to 85 DEG C up to oil 0.5% xanthans and 3% glycerine are added into 76.6% deionized water for phase, and are heated with stirring to 85 DEG C up to water phase, by gained Oil phase continues to stir under vacuum, and water phase is then added into oil phase, and continues to stir and emulsify, after emulsification, after continuation of insurance Temperature stirring 15min is added sodium hydroxide and adjusts pH to neutrality after being cooled to 40 DEG C, add 0.2% Phenoxyethanol, 3% anti-ageing Smoothing wrinkle composition 2 and 0.2% essence, stir.
Embodiment 6
A kind of preparation method of anti-ageing anti-wrinkle mask is as follows:According to mass percent, by 10% propylene glycol, 0.03% nicotinoyl Amine, 8% glycerine, 15% butanediol, 3% beta glucan, 0.05% Sodium Hyaluronate, 0.05% panthenol, 0.5% allantoin, 0.6% hexylene glycol, 0.3%EDTA disodiums, 0.3% hydroxyethyl cellulose, 0.2% carbomer, the addition of 58.77% deionized water are stirred It mixes and is heated with stirring to 85 DEG C in pot, stirring and dissolving is complete, and water phase is made;By 0.3% glycerine polymethacrylates, 0.8% water Solution Jojoba esters, 0.5%PEG-40 rilanit specials, which are added in agitated kettle, is heated with stirring to 85 DEG C, and oil phase is made;Under stirring, The oil phase is added to the aqueous phase, stirs evenly;It is cooled to 45 DEG C, 0.1% triethanolamine is added, stirs evenly, add 1% and anti-ageing remove Wrinkle composition 3,0.5% Phenoxyethanol, stirs postcooling discharging.
Human efficiency evaluates
The product and a commercially available cosmetics (control group) with anti-ageing wrinkle removing effect prepared to embodiment 4~6 carries out Detection result on probation.Test object:Each experimental group is 30 women (25~50 years old);Persistently use 4 weeks;Test event:Flesh Skin elastic effect, moistening effect, anti-wrinkle effect.Result on trial see the table below 2:
Table 2
As can be seen from Table 2, the elasticity of skin of product prepared by embodiment 4~6, moisturizing and anti-wrinkle effect improve apparent people Number is more than control group, illustrates that product of the present invention is able to maintain that skin moisture, improves elasticity of skin, effectively play the work of anti-ageing smoothing wrinkle With.
Above example only illustrates embodiment of the present invention, and there is no have limitation in any form to the present invention;Appoint What is engaged in professional and technical personnel, all has the ability to make some changes or modification using the technology contents disclosed, becomes equivalent The equivalent embodiment of variation carries out simple modification, equivalent change and modification to the present invention, belongs to according to the technology of the present invention essence In the range of technical solution of the present invention.

Claims (10)

1. a kind of anti-ageing smoothing wrinkle composition, it is characterised in that:
Moisturizer 10~18
Antioxidant 3~8
Firm renovation agent 5~11
It is mass parts above;
Wherein, antioxidant includes one or more of in sea cucumber gum former peptide, Purslane extract, vitamin E and its derivative;
It is one or more of in Firm renovation agent including collagen, epidermal growth factor, left-handed C stostes, ginseng extract.
2. composition as described in claim 1, it is characterised in that:
Moisturizer 12~16
Antioxidant 4~6
Firm renovation agent 7~9
It is mass parts above;
Wherein, antioxidant includes one or more of in sea cucumber gum former peptide, Purslane extract, vitamin E and its derivative;
It is one or more of in Firm renovation agent including collagen, epidermal growth factor, left-handed C stostes, ginseng extract.
3. composition as claimed in claim 2, it is characterised in that:
Moisturizer 14
Antioxidant 5
Firm renovation agent 8
It is mass parts above;
Wherein, antioxidant includes one or more of in sea cucumber gum former peptide, Purslane extract, vitamin E and its derivative;
It is one or more of in Firm renovation agent including collagen, epidermal growth factor, left-handed C stostes, ginseng extract.
4. composition as described in claim 1, it is characterised in that:
The moisturizer includes one or more of in rose, small molecule sodium hyaluronate, glucan, glycerine, glycine betaine.
5. composition as claimed in claim 2, it is characterised in that:
The moisturizer includes one or more of in rose, small molecule sodium hyaluronate, glucan, glycerine, glycine betaine.
6. composition as claimed in claim 3, it is characterised in that:
The moisturizer includes one or more of in rose, small molecule sodium hyaluronate, glucan, glycerine, glycine betaine.
7. composition as described in claim 1, it is characterised in that can be used for cosmetics.
8. composition as claimed in claim 2, it is characterised in that can be used for cosmetics.
9. composition as claimed in claim 3, it is characterised in that can be used for cosmetics.
10. such as claims 1 to 3 any one of them composition, it is characterised in that can be used as additive for anti-ageing, smoothing wrinkle class Cosmetics.
CN201810351276.2A 2018-04-17 2018-04-17 A kind of anti-ageing smoothing wrinkle composition Withdrawn CN108324587A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109091428A (en) * 2018-09-10 2018-12-28 天津郁美净集团有限公司 A kind of skin care compositions and preparation method thereof with anti-oxidation efficacy
CN114009794A (en) * 2021-11-05 2022-02-08 上海极迦生物科技有限公司 Composition with function of delaying skin aging and application thereof
CN114917143A (en) * 2022-05-19 2022-08-19 大连大学 Skin aging resistant sea cucumber polypeptide repair essence and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109091428A (en) * 2018-09-10 2018-12-28 天津郁美净集团有限公司 A kind of skin care compositions and preparation method thereof with anti-oxidation efficacy
CN114009794A (en) * 2021-11-05 2022-02-08 上海极迦生物科技有限公司 Composition with function of delaying skin aging and application thereof
CN114009794B (en) * 2021-11-05 2024-01-16 上海极迦生物科技有限公司 Composition with skin aging delaying function and application thereof
CN114917143A (en) * 2022-05-19 2022-08-19 大连大学 Skin aging resistant sea cucumber polypeptide repair essence and preparation method thereof

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Application publication date: 20180727