CN108310348A - A kind of preparation method of breath freshening spraying medicament - Google Patents
A kind of preparation method of breath freshening spraying medicament Download PDFInfo
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- CN108310348A CN108310348A CN201810356740.7A CN201810356740A CN108310348A CN 108310348 A CN108310348 A CN 108310348A CN 201810356740 A CN201810356740 A CN 201810356740A CN 108310348 A CN108310348 A CN 108310348A
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- breath freshening
- preparation
- spraying medicament
- essential oil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
Abstract
The invention discloses a kind of preparation methods of breath freshening spraying medicament comprising following processing step：1) 10~20 parts of fish glues are dissolved in aqueous solutions of organic acids, green tea powder is added, obtains rubber cement；2) 25~30 parts of compound fruit inspissated juices are uniformly mixed with 1~3 part of hyaluronic acid, instill compound essential oil, obtains fruity mixed liquor；3) it takes 3~5 parts of honey and 5~10 parts of Chinese herbal medicine extracts to be uniformly mixed, adds rubber cement and fruity mixed liquor, obtain finished product.The compound essential oil drop of the present invention is uniformly suspended in spraying medicament, as the stabilizer and preservative in its system, and has effects that excellent anti-inflammation and sterilization, it is aided with float for fishing glue as one of medicinal ingredient carrier simultaneously, improve its stock dispersion performance, absorbent properties and medicinal timeliness, so that the breath freshening spraying medicament has significant treatment canker sore, swelling and aching of gum, bleeding gums and other effects, while having effects that breath freshening and anti-inflammatory maintenance.
Description
Technical field
The present invention relates to dentistry field, more particularly to a kind of breath freshening spraying.
Background technology
For the oral cavities such as canker sore, bleeding gums common disease, existing therapy is divided into local application and takes orally
Two kinds of medicine, the wherein product of local application have diversification, including spraying, pad pasting, pulvis etc., are used wherein spraying because it has
Conveniently, increasingly favored by patient the advantages that comfortable taste.However, the treatment drug effect of existing mouthspray still needs
It improves, and its drug effect is more single, without preferable later stage repair.
Invention content
It is an object of the invention in view of the above shortcomings of the prior art, provide a kind of preparation of breath freshening spraying medicament
Method, gained spraying has significant treatment canker sore, swelling and aching of gum, bleeding gums and other effects, while having implication clear
The effect of new and anti-inflammatory maintenance.
The technical solution used in the present invention is：A kind of preparation method of breath freshening spraying medicament comprising following work
Skill step：
1) 10~20 parts of fish glues are dissolved in the aqueous solutions of organic acids of 1~2 times of parts by weight based on parts by weight of raw materials, are added
The green tea powder after 400~600 mesh sieve is crossed, stirs evenly, obtains rubber cement, it is spare；
2) 25~30 parts of compound fruit inspissated juices are uniformly mixed based on parts by weight of raw materials with 1~3 part of hyaluronic acid, are instilled
Compound essential oil stirs 5~10min under 40~45 DEG C of temperature conditions, obtains fruity mixed liquor, spare；
3) it takes 3~5 parts of honey and 5~10 parts of Chinese herbal medicine extracts to be uniformly mixed at room temperature based on parts by weight of raw materials, then adds
Enter fruity mixed liquor obtained by rubber cement and step 2) obtained by step 1), 1~3min of ultrasonication obtains finished product.
As being further improved for said program, the step 1) fish glue is sciaenoid, gadus, extra large soft-shelled turtle, sturgeon or carp
The air bladder of fish is made.
As being further improved for said program, the step 1) aqueous solutions of organic acids is the acetic acid of 0.01~0.1mol/L
Aqueous solution or aqueous citric acid solution.
As being further improved for said program, step 2) the compound fruit inspissated juice is selected from fragrant citrus inspissated juice, blueberry
Inspissated juice, strawberry inspissated juice, grapefruit inspissated juice, unusual fruit concentrated juice, grape inspissated juice, mango concentrated juice, guava inspissated juice
In at least two.
As being further improved for said program, the step 2) compound essential oil is selected from Lavender, lemon, rose
At least two in rare essential oil, tea tree ethereal oil, Peppermint essential oil, refined jasmine oil, flores aurantii essential oil.
As being further improved for said program, the step 2) Chinese herbal medicine extract by pseudo-ginseng, peppermint, rhizoma zingiberis, aloe,
Safflower is 1 by parts by weight of raw materials ratio:1:1:1:1 extracted forms.Specifically, the Chinese herbal medicine extract is to canker sore, tooth
Gum swells and ache and bleeding gums have significant therapeutic efficiency.
The beneficial effects of the invention are as follows：
The compound essential oil drop of the present invention is uniformly suspended in spraying medicament, as the stabilizer and anti-corrosion in its system
Agent, and have effects that excellent anti-inflammation and sterilization, it is used in combination compound fruit inspissated juice to reduce the toxic side effect and mouth of Chinese herbal medicine extract
Taste sense of discomfort, while being aided with float for fishing glue as one of medicinal ingredient carrier, improve its stock dispersion performance, absorbent properties and
Medicinal timeliness so that the breath freshening spraying medicament has the work(such as significant treatment canker sore, swelling and aching of gum, bleeding gums
Effect, while having effects that breath freshening and anti-inflammatory maintenance.
Specific implementation mode
The present invention is specifically described with reference to embodiment, in order to technical field personnel to the present invention
Understand.It is necessary to it is emphasized that embodiment is only intended to, the present invention will be further described herein, should not be understood as to this
The limitation of invention protection domain, fields person skilled in the art, the non-intrinsically safe that the present invention is made according to foregoing invention content
The modifications and adaptations of property, should still fall within protection scope of the present invention.Mentioned raw materials following simultaneously are unspecified, are
Commercial product；The processing step or preparation method not referred in detail be processing step known to a person skilled in the art or
Preparation method.
Embodiment 1
A kind of preparation method of breath freshening spraying medicament comprising following processing step：
1) 10 parts of fish glues made from the air bladder of sciaenoid are dissolved in 2 times of parts by weight based on parts by weight of raw materials
In the aqueous acetic acid or aqueous citric acid solution of 0.01mol/L, the green tea powder after 600 mesh sieve was added, stirs evenly, obtains glue
Slurry, it is spare；
2) 25 parts of compound fruit inspissated juices are uniformly mixed based on parts by weight of raw materials with 3 parts of hyaluronic acids, instill compound essence
Oil stirs 10min under 40 DEG C of temperature conditions, obtains fruity mixed liquor, spare；
3) it takes 3 parts of honey and 10 parts of Chinese herbal medicine extracts to be uniformly mixed at room temperature based on parts by weight of raw materials, adds step
1) gained rubber cement and step 2) gained fruity mixed liquor, ultrasonication 1min obtain 1 finished product of embodiment.
Wherein, step 2) the compound fruit inspissated juice is the mixed of fragrant citrus inspissated juice, grapefruit inspissated juice and mango concentrated juice
Close object；The compound essential oil is the mixture of Lavender, lemon and Peppermint essential oil；The Chinese herbal medicine extract is by field
Seven, peppermint, rhizoma zingiberis, aloe, safflower are 1 by parts by weight of raw materials ratio:1:1:1:1 extracted forms.
Embodiment 2
A kind of preparation method of breath freshening spraying medicament comprising following processing step：
1) 20 parts of fish glues made from the air bladder of sturgeon are dissolved in the 0.1mol/L of 1 times of parts by weight based on parts by weight of raw materials
Aqueous acetic acid or aqueous citric acid solution in, be added 400 mesh sieve after green tea powder, stir evenly, obtain rubber cement, it is spare；
2) 30 parts of compound fruit inspissated juices are uniformly mixed based on parts by weight of raw materials with 1 part of hyaluronic acid, instill compound essence
Oil stirs 5min under 45 DEG C of temperature conditions, obtains fruity mixed liquor, spare；
3) it takes 5 parts of honey and 5 parts of Chinese herbal medicine extracts to be uniformly mixed at room temperature based on parts by weight of raw materials, adds step 1)
Fruity mixed liquor obtained by gained rubber cement and step 2), ultrasonication 3min obtain 2 finished product of embodiment.
Wherein, step 2) the compound fruit inspissated juice is the mixed of blueberry inspissated juice, strawberry inspissated juice and grape inspissated juice
Close object；The compound essential oil is the mixture of Rosa Damascana, refined jasmine oil and flores aurantii essential oil；The Chinese herbal medicine extract is by field
Seven, peppermint, rhizoma zingiberis, aloe, safflower are 1 by parts by weight of raw materials ratio:1:1:1:1 extracted forms.
Embodiment 3
A kind of preparation method of breath freshening spraying medicament comprising following processing step：
1) by fish glue made from 15 parts of air bladders with sciaenoid, gadus, extra large soft-shelled turtle, sturgeon or carp based on parts by weight of raw materials
It is dissolved in the aqueous acetic acid or aqueous citric acid solution of the 0.05mol/L of 1.5 times of parts by weight, the green tea after 500 mesh sieve was added
Powder stirs evenly, and obtains rubber cement, spare；
2) 26 parts of compound fruit inspissated juices are uniformly mixed based on parts by weight of raw materials with 2 parts of hyaluronic acids, instill compound essence
Oil stirs 8min under 42 DEG C of temperature conditions, obtains fruity mixed liquor, spare；
3) it takes 4 parts of honey and 8 parts of Chinese herbal medicine extracts to be uniformly mixed at room temperature based on parts by weight of raw materials, adds step 1)
Fruity mixed liquor obtained by gained rubber cement and step 2), ultrasonication 2min obtain 3 finished product of embodiment.
Wherein, step 2) the compound fruit inspissated juice is the mixture of fragrant citrus inspissated juice and guava inspissated juice；It is described
Compound essential oil is the mixture of lemon, tea tree ethereal oil and flores aurantii essential oil；The Chinese herbal medicine extract is by pseudo-ginseng, peppermint, dry
Ginger, aloe, safflower are 1 by parts by weight of raw materials ratio:1:1:1:1 extracted forms.
Above-described embodiment is the preferred embodiment of the present invention, it is all with similar technique of the invention and made by equivalence changes,
The protection category of the present invention should all be belonged to.
Claims (6)
1. a kind of preparation method of breath freshening spraying medicament, it is characterised in that comprise the technical steps that：
1) 10~20 parts of fish glues are dissolved in the aqueous solutions of organic acids of 1~2 times of parts by weight based on parts by weight of raw materials, were added
Green tea powder after 400~600 mesh sieve, stirs evenly, obtains rubber cement, spare；
2) 25~30 parts of compound fruit inspissated juices are uniformly mixed based on parts by weight of raw materials with 1~3 part of hyaluronic acid, instill compound
Essential oil stirs 5~10min under 40~45 DEG C of temperature conditions, obtains fruity mixed liquor, spare；
3) it takes 3~5 parts of honey and 5~10 parts of Chinese herbal medicine extracts to be uniformly mixed at room temperature based on parts by weight of raw materials, adds step
Fruity mixed liquor obtained by rapid 1) gained rubber cement and step 2), 1~3min of ultrasonication obtain finished product.
2. a kind of preparation method of breath freshening spraying medicament according to claim 1, it is characterised in that：Step 1) is described
Fish glue is that the air bladder of sciaenoid, gadus, extra large soft-shelled turtle, sturgeon or carp is made.
3. a kind of preparation method of breath freshening spraying medicament according to claim 1, it is characterised in that：Step 1) is described
Aqueous solutions of organic acids is the aqueous acetic acid or aqueous citric acid solution of 0.01~0.1mol/L.
4. a kind of preparation method of breath freshening spraying medicament according to claim 1, it is characterised in that：Step 2) is described
Compound fruit inspissated juice is selected from fragrant citrus inspissated juice, blueberry inspissated juice, strawberry inspissated juice, grapefruit inspissated juice, unusual fruit concentrated juice, Portugal
At least two in grape inspissated juice, mango concentrated juice, guava inspissated juice.
5. a kind of preparation method of breath freshening spraying medicament according to claim 1, it is characterised in that：Step 2) is described
Compound essential oil is selected from Lavender, lemon, Rosa Damascana, tea tree ethereal oil, Peppermint essential oil, refined jasmine oil, flores aurantii essential oil
In at least two.
6. a kind of preparation method of breath freshening spraying medicament according to claim 1, it is characterised in that：Step 2) is described
Chinese herbal medicine extract is 1 by parts by weight of raw materials ratio by pseudo-ginseng, peppermint, rhizoma zingiberis, aloe, safflower:1:1:1:1 extracted forms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810356740.7A CN108310348A (en) | 2018-04-18 | 2018-04-18 | A kind of preparation method of breath freshening spraying medicament |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810356740.7A CN108310348A (en) | 2018-04-18 | 2018-04-18 | A kind of preparation method of breath freshening spraying medicament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108310348A true CN108310348A (en) | 2018-07-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810356740.7A Pending CN108310348A (en) | 2018-04-18 | 2018-04-18 | A kind of preparation method of breath freshening spraying medicament |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109464308A (en) * | 2018-11-15 | 2019-03-15 | 广东轻工职业技术学院 | A kind of essential oil composition and application with anti-blue light skin-care effect |
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| CN107875243A (en) * | 2017-11-24 | 2018-04-06 | 张龙兵 | Spray liquid for fresh breath |
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2018
- 2018-04-18 CN CN201810356740.7A patent/CN108310348A/en active Pending
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| CN102406559A (en) * | 2010-09-25 | 2012-04-11 | 董根荣 | Oral cavity refreshing spray with functions of diminishing inflammation and stopping bleeding and preparation method for oral cavity refreshing spray |
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| CN105125586A (en) * | 2015-09-23 | 2015-12-09 | 滨州医学院 | Isinglass oral ulcer film as well as preparation method and application thereof |
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| CN107648309A (en) * | 2017-10-17 | 2018-02-02 | 邹伟 | A kind of oral spray of swelling and pain relieving |
| CN107875243A (en) * | 2017-11-24 | 2018-04-06 | 张龙兵 | Spray liquid for fresh breath |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109464308A (en) * | 2018-11-15 | 2019-03-15 | 广东轻工职业技术学院 | A kind of essential oil composition and application with anti-blue light skin-care effect |
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Application publication date: 20180724 |
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