CN108310092A - A kind of Chinese medicine for treating acute cholecystitis - Google Patents
A kind of Chinese medicine for treating acute cholecystitis Download PDFInfo
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- A61K2236/30—Extraction of the material
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- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The present invention relates to a kind of Chinese medicines for treating acute cholecystitis, it is prepared by the raw medicinal material of following weight proportion:5 parts of rheum officinale, 30 parts of desmodium, 15 parts of oriental wormwood, 9 parts of cape jasmine, 9 parts of corydalis tuber, 9 parts of radix scutellariae, 6 parts of root of Aucklandia lappa Decne, 6 parts of radix bupleuri, 9 parts of the dried immature fruit of citron orange.Clinical experiments have proved that the present invention can safely and effectively treat acute cholecystitis.
Description
Technical field
The present invention relates to a kind of Chinese medicines, and in particular to a kind of Chinese medicine for treating acute cholecystitis.
Background technology
Acute cholecystitis is the gallbladder inflammation caused by gall-bladder pipe choking and bacteria attack, is the common disease of gall-bladder.
Its incidence is only second to appendicitis in abdominal surgery, this disease is more common in 35~55 years old a middle-aged person, and women morbidity is compared with male
It is more, it is more common in fat and multiple pregnancies women especially.The common complication hydrops of gallbladder, white bile, milk of lime bile, porcelain sample courage
Capsule, perforation of gallbladder, Biliary-digestive fistula, hepatapostema.Acute cholecystitis illness:Many patients fall ill after midnight into greasy dinner, because
High fat diet can make gall-bladder reinforce shrinking, and lie down and be easy to small cholelith slide-in and incarceration cystic duct.It is mainly shown as upper right abdomen
Rest pain, paroxysmal aggravation, can shoulder back of the body radiation to the right;Often occur together heat, nausea and vomiting, but it is rare to shiver with cold, and jaundice is light.Abdomen
It checks and finds that upper right abdomen is full, gallbladder area tension of abdominal muscle, apparent tenderness, Blumberg's sign.
Medicinal material present Research involved in the present invention is as follows:
Rheum officinale【Source】This product is the drying root and rhizome of polygonum rheum palmatum, Rheum tanguticum Maxim or Rheum officinale.Qiu Mo
Excavation before cauline leaf is withered or secondary spring is germinateed, removes radicula, scrapes off crust, valve cutting or section, restricts and wears bunchiness drying or convection drying.
【Nature and flavor】Hardship is trembled with fear.【Channel tropism】Returns spleen, stomach, large intestine, liver, pericardium channel.【Major function】Purge heat logical intestines, removing pattogenic heat from the blood and toxic material from the body, logical by the stasis of blood
Through.For real heat constipation, stagnate abdominal pain, and rush down dysentery is not well, jaundice with damp-heat pathogen, blood-head tells nosebleed, hot eyes, pharynx swelling, abdominalgia with intestinal abscess, carbuncle swells malignant boil
Sore, blood stasis closed, traumatic injury control scald outside;Upper gastrointestinal bleeding.Rheum palmatum (processed with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For mesh
Red pharynx swelling, gingivitis.Prepared RADIX ET RHIZOMA RHEI, which rushes down, to be exerted oneself to delay, purging intense heat and detonicating.For pathogenic fire,toxin and furuncles.Charred RADIX ET RHIZOMA RHEI cooling blood and removing stasis stops blooding.For
Blood-head has stasis of blood haemorrhage.【Usage and dosage】It is for oral administration:Decoction, 3~30g.【Pay attention to】Pregnant woman uses with caution.【It takes passages】《Chinese book on Chinese herbal medicine》
Desmodium【Alias】Christina loosestrife herb, to seat grass, roadside yellow, everywhere Huang, copper coin grass, a string of money, very little bone seven.【Source】This product
For the drying herb of Ofthe Primulaceae Lysimachia christinae.Summer, the harvesting of two season of autumn, remove impurity, dry.【Nature and flavor】It is sweet, salty, it is slightly cold.
【Channel tropism】Return liver, courage, kidney, bladder warp.【Major function】Eliminating dampness and heat, treating stranguria, detumescence.For heat gonorrhea, Sha Lin, urine is puckery to have a pain,
Jaundice, carbuncle swells furunculosis, venomous snake bite;Liver and bile stone, lithangiuria.【Usage and dosage】It is for oral administration:Decoction, 15~60g.【Note
Meaning】The all poison of all the moon subcutaneous ulcers, splenasthenic diarrhea person avoid and smash juice life clothes.【It takes passages】《Chinese book on Chinese herbal medicine》.
Oriental wormwood【Alias】Capillary wormwood, Artemisia capillaris, Artemisia stelleriana, suede wormwood artemisia, monkey hair.【Source】Product are feverfew artemisia scoparia or oriental wormwood
The dry aerial parts of wormwood artemisia.It is tapped when harvesting or autumn bud grow up to when spring seedling high 6~10cm, removes impurity and old stem,
It dries.The spring habit of harvesting claims " capillary wormwood ", the title " Artemisia capillaris " that autumn taps.【Nature and flavor】It is bitter, pungent, it is slightly cold.【Channel tropism】Return
Spleen, stomach, liver, gallbladder channel.【Major function】Clearing away damp-heat, removing jaundice subcutaneous ulcer.For jaundice oliguria, itchy sore;Infectious jaundice type hepatitis.
【Usage and dosage】It is for oral administration:Decoction, 6~15g.【It takes passages】《Chinese book on Chinese herbal medicine》.
Cape jasmine【Alias】Yellow Fructus Gardeniae, yellow fruit tree, fructus gardeniae, Fructus Gardeniae.【Source】This product is the dry of madder wort cape jasmine
Dry ripening fruits, root can also be used as medicine.9~November, fruit maturation harvested when being in reddish yellow, removes carpopodium and impurity, steams supreme
Vapour sets slightly boiling hot in boiling water, taking-up, drying.Root summer and autumn are excavated, and are cleaned and are dried.【Nature and flavor】Hardship is trembled with fear.【Channel tropism】The thoughts of returning home, lung, three
Jiao Jing.【Major function】Fruit:Purging intense heat relieving restlessness, reducing fever and causing diuresis, removing pattogenic heat from the blood and toxic material from the body.For Vexed, jaundice, blood strangury is puckery
Bitterly, blood-head tells nosebleed, red eye, swell pain, pathogenic fire,toxin and furuncles;Control bruise pain outside.【Usage and dosage】It is for oral administration:Decoction, 6~9g.【Pay attention to】Spleen
Empty loose stool person avoids clothes.【It takes passages】《Chinese book on Chinese herbal medicine》.
Corydalis tuber【Alias】Profound Hu Su, corydalis tuber prolong recklessly.【Source】This product is the dry tuber of papaveraceae plant corydalis.
Early summer cauline leaf is excavated when withered, removes fibrous root, is cleaned, and is set when boiled in boiling water to proper without the white heart, is taken out, dry.【Nature and flavor】Pungent,
Hardship, temperature.【Channel tropism】Return liver, the spleen channel.【Major function】Promoting blood circulation, sharp gas, analgesic.For chest side of body, epigastric pain, closed dysmenorrhea, production
Stasis blocking afterwards, tumbling and swelling.【Usage and dosage】It is for oral administration:Decoction, 3-9g.【Pay attention to】Pregnant woman uses with caution.【It takes passages】《Chinese book on Chinese herbal medicine》.
Radix scutellariae【Alias】Radix Scutellariae, scutellaria tea, tsuchikane tea root.【Source】This product is the drying of labiate radix scutellariae
Root.Spring, the excavation of two season of autumn, remove fibrous root and silt, hit tertia after solarization, dry.【Nature and flavor】Hardship is trembled with fear.【Channel tropism】Return lung, courage,
Spleen, large intestine, small intestinl channel.【Major function】Heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, tocolysis.It is wet for damp-warm syndrome, heat temperature chest tightness and emesis
Hot feeling of fullness, rush down dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, fetal irritability.【Usage and dosage】It is for oral administration:
Decoction, 3-9g.【Pay attention to】Fructus Corni, keel make for it.It is real to dislike green onion.Fear cinnabar, tree peony, black false hellebore.【It takes passages】《Chinese book on Chinese herbal medicine》.
Root of Aucklandia lappa Decne【Alias】Aplotaxis auriculata, costus root.【Source】This product is the dry root of feverfew root of Aucklandia lappa Decne.Autumn, two season of winter
Excavation, removes silt and fibrous root, segment, and big vertical profile again hits tertia at valve after dry.【Nature and flavor】It is pungent, bitter, temperature.【Channel tropism】
Returns spleen, stomach, large intestine, three burnt, gallbladder channels.【Major function】Promoting qi circulation and relieving pain, reinforcing spleen to promote digestion.For chest gastral cavity distending pain, weight after rush down dysentery, food
Product does not disappear, do not feel like eating.Roasted RADIX AUCKLANDIAE reality intestines antidiarrheal.For stomachache of having loose bowels.【Usage and dosage】It is for oral administration:Decoction, 1.5~6g.【Note
Meaning】The deficiency of Yin body fluid deficiency careful clothes of person.【It takes passages】《Chinese book on Chinese herbal medicine》.
Radix bupleuri【Alias】Ground smokes, Asia puecon recklessly, mountain dish eats grass, faggot.【Source】This product is umbelliferae bupleurum or narrow leaf bavin
The dry root of Hu.By character difference, practises claim " Bupleurum Chinese " and " RADIX BUPLEURI SCORZONERAEFOLII " respectively.Spring, the excavation of two season of autumn, remove cauline leaf and mud
Sand, it is dry.【Nature and flavor】Hardship is slightly cold.【Channel tropism】Return liver, gallbladder channel.【Major function】It is soothing the liver in inducing diaphoresis, rising Yang.For catching a cold
Fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, rectal prolapse.【Usage and dosage】It is for oral administration:Decoction, 3~9g.【Note
Meaning】The dry rhizome of bigleaf thorowax root, the dense link in surface is toxic, can not work as radix bupleuri and use.【It takes passages】《Chinese book on Chinese herbal medicine》.
The dried immature fruit of citron orange【Source】This product is rutaceae bitter orange and its drying young fruit of variety or sweet orange.5~June collects
From the fruit fallen, impurity is removed, is cut cross from the middle to two halves, dry or low temperature dry, the direct dry or low temperature dry of smaller.
【Nature and flavor】It is bitter, pungent, sour, temperature.【Channel tropism】Returns spleen, stomach.【Major function】Relieving stagnant Qi disperse accumulation, resolving sputum dissipate ruffian.For internal stagnation, ruffian
Full distending pain, weight after rush down dysentery, constipation, phlegm stagnant gas hinder the obstruction of qi in the chest, accumulation of pathogens in chest;Gastroptosis, rectal prolapse, the prolapse of uterus.【Usage and dosage】It is interior
Clothes:Decoction, 3~9g.【Pay attention to】Pregnant woman uses with caution.【It takes passages】《Chinese book on Chinese herbal medicine》.
Invention content
The present invention is intended to provide a kind of Chinese medicine for treating acute cholecystitis, by selecting suitable medicinal material and its matching
Than achieving the purpose that safely and effectively to cure acute cholecystitis.
In order to achieve the above object, the present invention uses following technical scheme:
A kind of Chinese medicine for treating acute cholecystitis, which is characterized in that it is prepared by the raw medicinal material of following weight proportion
It forms:5 parts of rheum officinale, 30 parts of desmodium, 15 parts of oriental wormwood, 9 parts of cape jasmine, 9 parts of corydalis tuber, 9 parts of radix scutellariae, 6 parts of root of Aucklandia lappa Decne, 6 parts of radix bupleuri, trifoliate orange
It is 9 parts real.
The beneficial effects of the present invention will now be described with reference to clinical experimental data:
1, general information
Outpatient service and in hospital acute cholecystitis patient 60 are collected in inventor in October, 2012 ~ 2013 year altogether between October, are randomly divided into
Treatment group 40 and control group 20, treatment group man 20, female 20, the course of disease 5 ~ 9 days, average age 42.15 years old;Control group man
12, female 8, the course of disease 3 ~ 8 days, average age 38.25 years old.2 groups of genders, age and course of disease comparing difference are not statistically significant,
It is comparable.
Diagnostic criteria
Diagnostic criteria according to national acute cholecystitis clinical speciality meeting:(1), fall ill hurried, right Upper abdominal pain, nausea, vomit
It spits, can there is high fever or shiver with cold.(2), face of acute ill, it is seen that jaundice, the apparent tenderness of upper right abdomen, tension of abdominal muscle, Murphy sign sun
Property or the gall-bladder of accessible enlargement.(3), blood leukocytes number and neutrophil leucocyte ratio increase, shift to left or see toxic granulation.
(4), B it is super be diagnosis Main Basiss, can show that gollbladder dilation degree, hydrops, empyema, peribiliary exudation sexually revise.
2, test method
2.1 therapy
The oral present invention for the treatment of group is according to capsule made from specific embodiment 3,3 times a day.The course for the treatment of 10 days.
Control group takes orally JINDAN PIAN, and 4 tablets once, takes orally 3 times a day, the course for the treatment of 10 days.
3, criterion of therapeutical effect and treatment results
3.1 criterion of therapeutical effect
Integral × 100 before therapeutic index (n) one (integral one integrates after treating before treating)/treatment
Clinical cure:Symptom, sign therapeutic index are more than 90%, and blood picture is normal, and B ultrasound image is normal or the person of being obviously improved.
It is effective:Symptom, sign therapeutic index are more than 75%, and blood picture is normal, and B ultrasound gall-bladder image is obviously improved or improves
Person.
Effectively:Symptom, sign therapeutic index are taken more than 50%, blood picture is normal, and B ultrasound image has improvement.
In vain:Symptom, sign therapeutic index are less than 50%, and blood picture, B ultrasound gall-bladder image are without improver.
3.2 treatment results are shown in Table 1.
1 two groups of curative effects of table compare
Group | n | Clinic control | It is effective | Effectively | In vain | Total effective rate (%) | Serious adverse reaction example |
Treatment group | 40 | 10 | 21 | 7 | 2 | 95% | 0 |
Control group | 20 | 2 | 9 | 7 | 2 | 90% | 0 |
As it can be seen that drug produced by the present invention can safely and effectively treat acute cholecystitis, there is promotional value.
Specific implementation mode
In order to better understand with the implementation present invention, further illustrated the present invention with reference to specific embodiment.
Embodiment 1
It weighs:5 grams of rheum officinale, 30 grams of desmodium, 15 grams of oriental wormwood, 9 grams of cape jasmine, 9 grams of corydalis tuber, 9 grams of radix scutellariae, 6 grams of root of Aucklandia lappa Decne, radix bupleuri 6
Gram, 9 grams of the dried immature fruit of citron orange;Add 8 times of amount water, decocts 1.5 hours, filtering;Filter residue adds 6 times of amount water, decocts 1 hour, filtering;Merging filtrate,
120 grams are concentrated into get the decoction of one day dosage of normal adult is met.
For treating acute cholecystitis.It is oral, it is taken three times per bu Morning Afternoon Evening.
Embodiment 2
It weighs:5 grams of rheum officinale, 30 grams of desmodium, 15 grams of oriental wormwood, 9 grams of cape jasmine, 9 grams of corydalis tuber, 9 grams of radix scutellariae, 6 grams of root of Aucklandia lappa Decne, radix bupleuri 6
Gram, 9 grams of the dried immature fruit of citron orange;Add 10 times of amount water, decocts 2 hours, filtering;Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering;Merging filtrate,
Concentration, it is dry, it packs to get the powder of one day dosage of normal adult is met.
For treating acute cholecystitis.It is oral, it is taken three times per bu Morning Afternoon Evening.
Embodiment 3
It weighs:5 grams of rheum officinale, 30 grams of desmodium, 15 grams of oriental wormwood, 9 grams of cape jasmine, 9 grams of corydalis tuber, 9 grams of radix scutellariae, 6 grams of root of Aucklandia lappa Decne, radix bupleuri 6
Gram, 9 grams of the dried immature fruit of citron orange;Add 6 times of amount water, decocts 3 times, decoct 1 hour every time, merge decoction liquor, concentrate, it is dry, capsule shells are packed into, i.e.,
The capsule of one day dosage of normal adult must be met.
For treating acute cholecystitis.It is oral, it is taken three times per bu Morning Afternoon Evening.
Claims (4)
1. a kind of Chinese medicine for treating acute cholecystitis, which is characterized in that it is by the raw medicinal material system of following weight proportion
It is standby to form:5 parts of rheum officinale, 30 parts of desmodium, 15 parts of oriental wormwood, 9 parts of cape jasmine, 9 parts of corydalis tuber, 9 parts of radix scutellariae, 6 parts of root of Aucklandia lappa Decne, 6 parts of radix bupleuri,
9 parts of the dried immature fruit of citron orange.
2. being used for the Chinese medicine of acute cholecystitis as described in claim 1, which is characterized in that preparation method is:It weighs:Rheum officinale
5 parts, 30 parts of desmodium, 15 parts of oriental wormwood, 9 parts of cape jasmine, 9 parts of corydalis tuber, 9 parts of radix scutellariae, 6 parts of root of Aucklandia lappa Decne, 6 parts of radix bupleuri, 9 parts of the dried immature fruit of citron orange;Add 8
Amount water again decocts 1.5 hours, filtering;Filter residue adds 6 times of amount water, decocts 1 hour, filtering;Merging filtrate is concentrated into 120 parts, i.e.,
Obtain decoction;Above-mentioned part each means parts by weight.
3. the Chinese medicine for treating acute cholecystitis as described in claim 1, which is characterized in that preparation method is:It weighs:
5 parts of rheum officinale, 30 parts of desmodium, 15 parts of oriental wormwood, 9 parts of cape jasmine, 9 parts of corydalis tuber, 9 parts of radix scutellariae, 6 parts of root of Aucklandia lappa Decne, 6 parts of radix bupleuri, the dried immature fruit of citron orange 9
Part;Add 10 times of amount water, decocts 2 hours, filtering;Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering;Merging filtrate concentrates, and does
It is dry, it packs to get powder;Above-mentioned part each means parts by weight.
4. the Chinese medicine for treating acute cholecystitis as described in claim 1, which is characterized in that preparation method is:It weighs:
5 parts of vehicle rheum officinale, 30 parts of desmodium, 15 parts of oriental wormwood, 9 parts of cape jasmine, 9 parts of corydalis tuber, 9 parts of radix scutellariae, 6 parts of root of Aucklandia lappa Decne, 6 parts of radix bupleuri, the dried immature fruit of citron orange 9
Part;Add 6 times of amount water, decocts 3 times, decoct 1 hour every time, merge decoction liquor, concentrate, it is dry, capsule shells are packed into get capsule
Agent;Above-mentioned part each means parts by weight.
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2017
- 2017-01-16 CN CN201710027598.7A patent/CN108310092A/en not_active Withdrawn
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Application publication date: 20180724 |