CN108309922A - One kind three spends proferment pulp cosmetic and preparation method thereof - Google Patents
One kind three spends proferment pulp cosmetic and preparation method thereof Download PDFInfo
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- CN108309922A CN108309922A CN201810200662.1A CN201810200662A CN108309922A CN 108309922 A CN108309922 A CN 108309922A CN 201810200662 A CN201810200662 A CN 201810200662A CN 108309922 A CN108309922 A CN 108309922A
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- powder
- cosmetics
- chamomile
- flower
- peach blossom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Abstract
The present invention provides one kind three to spend proferment pulp cosmetic, by lactobacillus plantarum a concentration of 106‑108The zymophyte bacterium solution of CFU/ml;Peach blossom powder;Chamomile powder;Rose flower;Glucose;Water is prepared.The invention also discloses a kind of preparation methods of three flowers proferment pulp cosmetic, the Preliminary fermentation system that powder and water, the zymophyte of peach blossom, chamomile, rose are obtained by mixing, supernatant obtained from obtained zymotic fluid is sterilized, centrifugation, the supernatant are three flower proferment pulp cosmetic.The present invention carries out whole plant fermentation using the flower of lactic acid bacteria pair three, remains the whole functional components and its activity of plant, and active constituent caused by avoiding extracting method is lost in, and keeps the natural activity of plant.There is outstanding antioxidant activity rich in Kaempferol, trifolin, vitamin, amino acid, rose polyphenol, mountain quercitrin etc. in product and inhibit TYR enzyme activity.
Description
Technical field:
The invention belongs to cosmetic fields, specifically a kind of three spend proferment pulp cosmetic and preparation method thereof.
Background technology:
The modern biotechnology of increasingly favor with the fast development and people of to(for) pure natural raw produce, increasingly
More people pays close attention to plant enzyme this kind of new product, however application of the ferment in flower class now is also less, is far from vegetables
It is widely used on fruit.The active constituent of flavonoids in chamomile also has the work(such as anti-oxidant, anti-inflammatory, antiangiogenic
Effect, is well suited for the skin for quickly pacifying easy allergy, can be mild keep the skin wet, skin of releiving is red itches.There is mountain in peach blossom
How the nutriments such as phenol, trifolin, beans essence, vitamin A, vitamin B and vitamin C.Wherein there is preferable beauty and skin care to imitate
Fruit is Kaempferol, and these substances have and can improve blood circulation, promotion of blood circulation, expansion blood vessel, promote skin oxygen and nutrition
Supply, moreover it is possible to accelerate make human senility lipofuscin element excretion, prevent melanin deposition in skin, it is certain to reach
Whitening function.Rich in amino acid, rose polyphenol, Kaempferol, beans essence, trifolin, abundant protein, dimension life in rose
Element, quercitrin, amaroid etc..Rose, which has, removes free radical and oxidation resistant effect.Lactic acid bacteria is at present in food industry
Application it is relatively abundant, such as can improve flavour of food products after food fermentation, have certain health-care effect, food can be improved
Keeping property can improve nutritive value of food etc..But now by streptococcus acidi lactici fermented solution on cosmetics or ratio
It is less, this be also from now on lactobacillus-fermented can walk one of direction.
Invention content:
For above-mentioned technical problem in the prior art, the present invention provides one kind three to spend proferment pulp cosmetic and its system
Preparation Method, described this three flowers proferment pulp cosmetic and preparation method thereof will connect cosmetics in the prior art and remove freely
Base and oxidation resistant ineffective technical problem.
The present invention provides one kind three to spend proferment pulp cosmetic, is prepared by following raw material:
Lactobacillus plantarum a concentration of 106-108The zymophyte bacterium solution of CFU/ml;
Peach blossom powder;
Chamomile powder;
Rose flower;
Glucose;
Water;
In the cosmetics, the concentration of volume percent of zymocyte liquid is 1-16%, and the pH of the cosmetics is
4.5-8.5;
In the cosmetics, the quality of glucose is the matter of water, peach blossom powder, chamomile powder and rose flower
The 1-16% of the sum of amount;
In the cosmetics, peach blossom powder, the quality sum of chamomile powder and rose flower and water quality
Solid-liquid ratio be 1:10-1:120;The mass ratio of peach blossom powder, chamomile powder and rose flower is arbitrary ratio.
Further, lactobacillus plantarum lactobacillus plantarum MRS-P89, the Lactobacillus plantarum.
Further, the mesh number of the mesh number 80-120 of the peach blossom powder, the chamomile powder are 80-120, institute
The mesh number for the rose flower stated is 80-120.
Further, the mesh number of the peach blossom powder is 100, and the mesh number of chamomile powder is 100, the mesh of rose flower
Number is 100.
Further, in the cosmetics, the concentration of volume percent of zymocyte liquid is 4%;The cosmetics
PH be 4.5;
In the cosmetics, the quality of glucose is the matter of water, peach blossom powder, chamomile powder and rose flower
The 4% of the sum of amount;;
In the cosmetics, peach blossom powder, the quality sum of chamomile powder and rose flower and water quality
Solid-liquid ratio be 1:100.
The present invention also provides a kind of above-mentioned methods preparing three flower proferment pulp cosmetic, include the following steps:
1) each raw material is weighed according to material ratio;
2) one prepares lactobacillus plantarum a concentration of 106-108The step of zymophyte bacterium solution of CFU/ml;
One the step of preparing peach blossom, chamomile, rose flower, will peach blossom, chamomile, rose flower mix after plus
Enter deionized water, glucose is then added, then it is 4.5-8.5 to adjust pH;
3) by the mixture of step 2) and zymocyte liquid mixed fermentation;
The zymotic fluid that above-mentioned steps obtain is sterilized successively, centrifuged, collects supernatant, obtains the peach blossom, ocean
Camomile, rose three spend proferment pulp cosmetic;
In the cosmetics, the concentration of volume percent of zymocyte liquid is 1-16%, and the pH of the cosmetics is
4.5-8.5;
In the cosmetics, the quality of glucose is the matter of water, peach blossom powder, chamomile powder and rose flower
The 1-16% of the sum of amount;
In the cosmetics, peach blossom powder, the quality sum of chamomile powder and rose flower and water quality
Solid-liquid ratio be 1:10-1:120;The mass ratio of peach blossom powder, chamomile powder and rose flower is arbitrary ratio.
Further, the bacillus lactobacillus plantarum is bacillus lactobacillus plantarum MRS-P89, Lactobacillus
plantarum。
Further, in the centrifugation step, rotating speed 4500-5500r/min, centrifugation time 15min.
The present invention also provides a kind of cosmetics, contain three above-mentioned flower proferment pulp cosmetic.The cosmetics are tool
Have and removes at least one of DPPH free radicals and inhibition TYR enzyme activity functional product.
The present invention is by zymophyte a concentration of 106-108The zymophyte bacterium solution of CFU/ml, 80-120 mesh peach blossom powder, 80-
120 mesh chamomile powder, 80-120 mesh rose flower and water mixed fermentation and obtain, obtained zymotic fluid is sterilized, centrifugation
Obtained supernatant is three flower proferment pulp cosmetic.The solid-liquid ratio of flower and water is 1:10-1:120, specially 1:100;Portugal
The mass percent concentration of grape sugar addition is 1~16%, specially 4%;In the fermentation step, fermentation temperature is 27-47 DEG C;
Fermentation time is 6-72 hours;The solid-liquid ratio of three flowers and water is 1:10-1:120;The concentration of volume percent of zymocyte liquid is 1-
16%;Initial pH is 4.5-8.5;Glucose additive amount is 1-16%.
The present invention by three flowers, i.e., peach blossom, chamomile, rose first originating of being obtained by mixing of powder and water, zymophyte
Ferment system, obtained zymotic fluid is sterilized, supernatant obtained from centrifugation.The present invention carries out whole plant using the flower of lactic acid bacteria pair three
Fermentation, remains the whole functional components and its activity of plant, and active constituent caused by avoiding extracting method is lost in.Fermentation temperature
Degree and fermentation pH are mild, and active components of plants structure is not destroyed, and keep the natural activity of plant, and perfume (or spice) is not added in magma of fermenting
The chemical compositions such as essence, it is ensured that safety of the product to human body.In product rich in Kaempferol, trifolin, vitamin, amino acid,
Rose polyphenol, mountain quercitrin etc. have outstanding antioxidant activity and inhibit TYR enzyme activity.
The present invention is compared with prior art, and technological progress is significant.The present invention is using lactobacillus plantarum to peach blossom, ocean
Camomile, the flower of rose three carry out whole plant fermentation, remain the whole functional components and its activity of plant, avoid extracting method
Caused by active constituent be lost in.Fermentation method of the present invention, fermentation temperature and fermentation pH are mild, active components of plants structure
It is not destroyed, keeps the natural activity of plant.Cosmetics provided by the invention after fermentation, essence are not added in magma of fermenting
Deng to chemical composition, it is ensured that safety of the product to human body.Peach blossom provided by the invention, chamomile, rose three spend proferment
Rich in having DPPH anti-oxidant and inhibiting tyrosinase activity active material in pulp cosmetic, to have to skin stronger anti-
Oxidation and whitening function, while there is synergistic effect with the ingredient in ferment filtrate.
Specific implementation mode:
The specific implementation mode of form by the following examples remakes further specifically the above of the present invention
It is bright, illustrate but does not limit the present invention.Unless otherwise specified, technological means used in embodiment is ripe for those skilled in the art
The conventional means known.
Three flowers are self-control used in the present invention, and larger-size particle is eliminated by screening after crushing.
The Guangdong lactobacillus plantarum Jun Gou institute of microbiology used in the present invention
Lactobacillus used in following embodiments is pre-processed in accordance with the following steps:
Fermentation process first activates lactobacillus plantarum strain, makes the higher viability of holding;Then bacterium is purified,
Make to use single culture when fermentation;Then spreading cultivation makes bacterium mass propagation.Bacterium access root of Rhodiola sachalinensis powder and water after spreading cultivation it is mixed
It closes liquid to ferment under conditions of adaptation, is then centrifuged for that supernatant is taken to be detected.
Detailed process is as follows:
(1) actication of culture:Picking colony is put into fluid nutrient medium from the inclined-plane of preservation, is put into shaking table and strain is lived
Change.
(2) purifying agaric:By the strain gradient dilution bed board of activation, to obtain single bacterium colony.
(3) strain spreads cultivation:For use strain is inoculated into respective liquid culture medium, is cultivated in 35~38 DEG C of shaking table,
When to its OD values=0.5-1.0, strain is in logarithmic phase, as suitable inoculum density 106-108CFU/ml.Used medium
Group becomes:MRS agar 6.6%, MRS meat soups 5%
Embodiment 1 three spends the preparation and detection of proferment pulp cosmetic
Feeding liquor ratio (quality) is 1:100 three pollen end (is between peach blossom powder, chamomile powder, rose flower
Arbitrary ratio;) it is added 4% glucose of mixed liquor quality with the mixed liquor of deionized water, then with food grade Na2CO3It adjusts initial
PH to 4.5 is added a concentration of 106-108The lactobacillus plantarum MRS-P89 of CFU/ml, after addition, in the cosmetics, institute
The concentration of volume percent for the yeast-like fungi liquid stated is 4%;It is cultivated for 24 hours in 37 DEG C of constant incubators.It is steamed after fermentation in high pressure
121 DEG C of sterilizing 15min in vapour autoclave.5000r/min centrifuges 15min, takes supernatant, fermentation Chinese wolfberry fruit as provided by the invention
Magma cosmetics.
The appearance that the embodiment prepares three flower proferment pulp cosmetic of gained is liquid, color is faint yellow to red.pH
Value is 3.2-4.8, and the mass percentage of soluble Solid content is 0.5-1.5%, and total plate count is less than 50CFU/ml, and nothing is caused a disease
Bacterium detects.Meet cosmetics quality requirement.
Constituent analysis is carried out to the three flowers proferment pulp cosmetic, protein detection method is with reference to GB5009.5-2010;Slightly
Polysaccharide detection method is with reference to GB/T 5009.8-2008;Amino acid detection method is with reference to GB/T 5009.124-2003 acquired results
It is as follows:
Three flower proferment pulp cosmetic produced by the present invention 1g/kg containing protein, Thick many candies 1.2g/kg, general flavone
0.023g/kg (in terms of rutin), total phenol 0.062g/kg.Total amino acid 0.579g/kg, including asparatate 0.024g/
Kg, threonine 0.014g/kg, serine 0.023g/kg, glutamic acid 0.059g/kg, glycine 0.051g/kg, alanine
0.024g/kg, valine 0.033g/kg, isoleucine 0.014g/kg, leucine 0.021g/kg, lysine 0.022g/kg,
Histidine 0.013g/kg, arginine 0.028g/kg, proline 0.037g/kg.
The flower fermentation magma anti-oxidation efficacy analysis of embodiment 2 three
DPPH is a kind of organic free radical of early stage synthesis, is commonly used to the hydrogen supply capacity of assessment polyphenoils, it is organic
It is highly stable in solvent, it is in purple, and there are one characteristic absorption peaks, when encountering free radical scavenger, the orphan of DPPH is to electricity
Son is paired and it is made to fade, that is, becomes smaller in the light absorption value of maximum absorption wave strong point.It therefore, can be by measuring light absorption value
Change to evaluate elimination effect of the sample to DPPH free radicals.
DPPH radicals scavengings experiment specific experiment step be:
(1) the DPPH solution mixing (A1 pipes) of the prepare liquid and 2 × 10mol/L of isometric (generally 3mL) is taken;
(2) the DPPH solution mixing (A2 pipes) of isometric absolute ethyl alcohol (determinand solvent) and 2 × 10-4mol/L is taken;
(3) isometric absolute ethyl alcohol and prepare liquid mixing (A3 pipes) are taken;
(4) after reacting 30min, A1, A2, A3 pipe absorbance value are surveyed at 517nm.
Clearance rate calculation formula is:Clearance rate (%)=[(A2+A3)-A1]/A2
Clearance rate shows that more greatly oxidation resistance is stronger.
The results are shown in Table 1.
Lactobacillus plantarum MRS-P89 fermentations magma inhibits DPPH free radicals under 1 optimal conditions of table
As shown in Table 1, under the optimal conditions that ferments, fermented supernatant fluid is to the clearance rates of DPPH free radicals, and clearance rate is high
Up to 92.06%.
Claims (10)
1. one kind three spends proferment pulp cosmetic, it is characterised in that be prepared by following raw material:
Lactobacillus plantarum a concentration of 106-108The zymophyte bacterium solution of CFU/ml;
Peach blossom powder;
Chamomile powder;
Rose flower;
Glucose;
Water;
In the cosmetics, the concentration of volume percent of zymocyte liquid is 1-16%, and the pH of the cosmetics is 4.5-
8.5;
In the cosmetics, the quality of glucose be water, peach blossom powder, chamomile powder and rose flower quality it
The 1-16% of sum;
In the cosmetics, the material of the quality of peach blossom powder, the quality sum of chamomile powder and rose flower and water
Liquor ratio is 1:10-1:120;The mass ratio of peach blossom powder, chamomile powder and rose flower is arbitrary ratio.
2. a kind of three flowers proferment pulp cosmetic according to claim 1, it is characterised in that:The lactobacillus plantarum is planted
Object lactobacillus MRS-P89, Lactobacillus plantarum.
3. a kind of three flowers proferment pulp cosmetic according to claim 1, it is characterised in that:The mesh of the peach blossom powder
The mesh number of number 80-120, the chamomile powder are 80-120, and the mesh number of the rose flower is 80-120.
4. a kind of three flowers proferment pulp cosmetic according to claim 3, it is characterised in that:The mesh number of the peach blossom powder
It is 100, the mesh number of chamomile powder is 100, and the mesh number of rose flower is 100.
5. a kind of three flowers proferment pulp cosmetic according to claim 1, it is characterised in that:The material of three flowers and water
Liquor ratio is 1:10;In the cosmetics, the concentration of volume percent of zymocyte liquid is 4%;Initial pH is 4.5;Described
Cosmetics in, the mass percent concentration of glucose is 4%.
6. a kind of method preparing three flower proferment pulp cosmetic described in claim 1, it is characterised in that include the following steps:
1) each raw material is weighed according to material ratio;
2) one prepares lactobacillus plantarum a concentration of 106-108The step of zymophyte bacterium solution of CFU/ml;
One the step of preparing peach blossom, chamomile, rose flower, is added after mixing peach blossom, chamomile, rose flower and goes
Then ionized water is added glucose, then adjusts pH;
3) by the mixture of step 2) and zymocyte liquid mixed fermentation;
The zymotic fluid that above-mentioned steps obtain is sterilized, is centrifuged, collects supernatant successively, obtain described in peach blossom, chamomile,
Rose three spends proferment pulp cosmetic;
In the cosmetics, the concentration of volume percent of zymocyte liquid is 1-16%;The pH of the cosmetics is 4.5-
8.5;
In the cosmetics, the mass percent concentration of glucose is 1-16%;
In the cosmetics, the solid-liquid ratio of peach blossom powder, the quality sum of chamomile powder and rose flower and water is
1:10-1:120。
7. a kind of method preparing three flower proferment pulp cosmetic according to claim 6, it is characterised in that:
The bacillus lactobacillus plantarum is bacillus lactobacillus plantarum MRS-P89, Lactobacillus plantarum.
8. a kind of method preparing three flower proferment pulp cosmetic according to claim 6, it is characterised in that:
In the cosmetics, the concentration of volume percent of zymocyte liquid is 4%;The pH of the cosmetics is 4.5;
In the cosmetics, the quality of glucose be water, peach blossom powder, chamomile powder and rose flower quality it
The 4% of sum;
In the cosmetics, the material of the quality of peach blossom powder, the quality sum of chamomile powder and rose flower and water
Liquor ratio is 1:100.
9. a kind of method preparing three flower proferment pulp cosmetic according to claim 6, it is characterised in that:
In the centrifugation step, rotating speed 4500-5500r/min, centrifugation time 15min.
10. a kind of cosmetics contain three flowers proferment pulp cosmetic described in claim 1.
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109874959A (en) * | 2019-03-18 | 2019-06-14 | 丘北诺香花卉农业科技开发有限公司 | A kind of extracting method of rose magma |
CN114632055A (en) * | 2022-03-17 | 2022-06-17 | 广州环亚化妆品科技股份有限公司 | Whitening and relieving plant fermentation product and preparation method and application thereof |
CN115531232A (en) * | 2022-06-28 | 2022-12-30 | 银谷芳香科技有限公司 | Preparation method and application of rose composite fermentation liquor rich in ellagic acid |
CN116549362A (en) * | 2023-07-10 | 2023-08-08 | 广州杨森药业有限公司 | Jasmine flower composition fermentation filtrate and preparation method and application thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104257598A (en) * | 2014-09-18 | 2015-01-07 | 北京工商大学 | Chinese wolfberry fermented raw stock cosmetic and preparation method thereof |
CN104257545A (en) * | 2014-09-18 | 2015-01-07 | 北京工商大学 | Rhodiola rosea fermentation protoplasm cosmetic and preparation method thereof |
CN105147586A (en) * | 2015-09-30 | 2015-12-16 | 上海全丽生物科技有限公司 | Rose fermentation puree as well as preparation method and application thereof |
-
2018
- 2018-03-12 CN CN201810200662.1A patent/CN108309922A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104257598A (en) * | 2014-09-18 | 2015-01-07 | 北京工商大学 | Chinese wolfberry fermented raw stock cosmetic and preparation method thereof |
CN104257545A (en) * | 2014-09-18 | 2015-01-07 | 北京工商大学 | Rhodiola rosea fermentation protoplasm cosmetic and preparation method thereof |
CN105147586A (en) * | 2015-09-30 | 2015-12-16 | 上海全丽生物科技有限公司 | Rose fermentation puree as well as preparation method and application thereof |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109874959A (en) * | 2019-03-18 | 2019-06-14 | 丘北诺香花卉农业科技开发有限公司 | A kind of extracting method of rose magma |
CN114632055A (en) * | 2022-03-17 | 2022-06-17 | 广州环亚化妆品科技股份有限公司 | Whitening and relieving plant fermentation product and preparation method and application thereof |
CN115531232A (en) * | 2022-06-28 | 2022-12-30 | 银谷芳香科技有限公司 | Preparation method and application of rose composite fermentation liquor rich in ellagic acid |
CN116549362A (en) * | 2023-07-10 | 2023-08-08 | 广州杨森药业有限公司 | Jasmine flower composition fermentation filtrate and preparation method and application thereof |
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