CN108309869A - It is a kind of to have effects that the skin care compositions of skin repair and its application - Google Patents
It is a kind of to have effects that the skin care compositions of skin repair and its application Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
Having effects that the skin care compositions of skin repair the invention discloses a kind of, includes the component of following parts by weight：0.1 10 parts of Kessazulen sodium sulfonate, 0.1 10 parts of Notogineng Extract.To together, Kessazulen sodium sulfonate promotes regeneration, the healing rate of acceleration of wound mouth for Kessazulen sodium sulfonate and Notogineng Extract compounding；Notogineng Extract shortens blood coagulation time, has anastalsis, activating blood and removing stasis to ensure the nutrition needed for regeneration, the two is synergistic, accelerates minimally invasive wound healing, promotes regeneration.
Description
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of to have effects that the skin care compositions of skin repair and its answer
With.
Background technology
Skin is the maximum organ of human body area.It makes various in vivo organize with organ from physical, mechanicalness, chemistry
The invasion of property and pathogenic microorganism.There are two the barrier actions of aspect for skin tool：When prevent moisture in vivo, electrolyte, its
He loses substance；Second is that preventing the intrusion of extraneous harmful substance.Skin remains the stabilization of human internal environment, while skin is also joined
With the metabolic process of human body.
With the development of society, various surface of a wound problems more and more frequently show.According to statistics, there is the population of about l% in the whole world
Perplexed by the surface of a wound problem of duration, about 5% medical expense is spent in wound repair.The especially chronic refractory of the surface of a wound
Surface of a wound incidence seriously affects people’s lives quality in trend is increased year by year.
Newest biotechnology thinks that skin repair and epidermal cell regeneration are an extremely complex processes, and skin is thin
The inducible factor mechanism of born of the same parents is also complicated.From cell biology angle, due to inducible factor induced cell growth
When, accelerate the metabolism of cell, produces a large amount of metabolite (such as free radical).A large amount of metabolites in the cell and
Accumulation in cytoplasm can have cell serious destruction and inhibiting effect.
Invention content
Having effects that the skin care compositions of skin repair the technical problem to be solved in the present invention is to provide a kind of, for impaired
Skin play reparation cuticula, provide nutrition for epidermal cell, accelerate the fast quick-recovery of epidermis, promote function of tissue regeneration；
Redness is eliminated, inflammation is prevented；And neoplastic skin or mucous membrane is made to keep appropriate soft and elasticity, human body is improved to external environment
Anti-stress ability and immunity.
The specific technical solution to solve the above problems is as follows：
It is a kind of to have effects that the skin care compositions of skin repair, include the component of following parts by weight：Kessazulen sodium sulfonate
0.1-10 parts, 0.1-10 parts of Notogineng Extract.
Further, the composition further includes the component of following parts by weight：0.1-10 parts of silk tree bark extract, reaches the clouds
0.1-10 parts of flower extract.
The present invention also provides described to have effects that application of the skin care compositions of skin repair in preparing cosmetics,
Wherein, the dosage with the skin care compositions of skin repair is the 0.1-10wt% of final products weight.
The present invention also provides a kind of skin repair frosts, include each component of following mass percentage：Above-mentioned skin repair
Composition 0.1-10%, ring five dimethyl silicone polymer 1-5%, caprylic/capric triglyceride 1-8%, double-PEG/PPG-16/
16PEG/PPG-16/16 dimethyl silicone polymers 0.1-2%, dimethyl silicone polymer 1-5%, isononyl isononanoate 1-5%, rice
(ORYZA SATIVA) oil extracted from rice husks 0.1-3%, glycerine polyacrylate 0.1-1%, cetostearyl alcohol 0.1-3%, glycerol stearate
Ester 0.1-1%, PEG-100 stearate 0.1-1%, PEG-20 methyl sesquistearate 0.1-1%, Queensland nut
(MACADAMIA TERNIFOLIA) seed oil 0.1-2%, oleyl alcohol eruciate 0.1-1%, Butyrospermum parkii (BUTYROSPERMUM
PARKII) fruit fat 0.5-3%, sodium acrylate/sodium acryloyldimethyl taurate copolymers 0.1-0.6%, polysorbate-
600.1-1%, isohexadecane 0.1-1%, stearic acid 0.1-1%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol
Dimerized linoleic acid ester 0.1-1%, tocopherol acetate 0.1-1%, polyalcohol 5-15%, pyrenomycetes (SCLEROTIUM
ROLFSSII) glue 0.1-1%, xanthans 0.05-0.3%, pectin 0.01-0.3%, carbomer 0.1-0.5%, dipotassium glycyrrhizinate
0.01-0.3%, arginine 0.1-0.5%, EDETATE SODIUM 0.01-0.05%, Sodium Hyaluronate 0.01-0.05%, Butylated Hydroxytoluene
0.01-0.1%, water surplus.
Further, the skin repair frost further includes the preservative of 0.3-0.7wt%, wherein the preservative is
At least one of potassium sorbate, benzyl alcohol, Phenoxyethanol.
Skin trauma is difficult to heal, and a part is the obstruction due to foreign body rejection to Regeneration and Repair, and another part is part
Blood circulation can not ensure the nutrition needed for regeneration.The present invention is arrived by Kessazulen sodium sulfonate and Notogineng Extract compounding
Together, synergistic, accelerate minimally invasive wound healing, promote regeneration, make neoplastic skin or mucous membrane keep it is appropriate it is soft with
Elasticity.
The present invention has the advantages that：
1, to together, Kessazulen sodium sulfonate promotes regeneration, adds for Kessazulen sodium sulfonate and Notogineng Extract compounding
The healing rate of fast wound mouth；Notogineng Extract shortens blood coagulation time, has anastalsis, activating blood and removing stasis to ensure tissue again
Raw required nutrition, the two is synergistic, accelerates minimally invasive wound healing, promotes regeneration.
2, the activating blood and removing stasis of silk tree bark extract and Flos Campsis extract subsides a swelling, the characteristic of promoting menstruation, compounds Kessazulen
Sodium sulfonate and Notogineng Extract have preferable repellent antipruritic effect, improve wound site blood circulation, strengthen epidermal tissue
Regeneration effect makes neoplastic skin or mucous membrane keep appropriate soft and elasticity.
3, the present composition is applied in skin repair frost, in addition to having hemostasis, accelerates minimally invasive wound healing, promotion group
Regeneration is knitted, so that neoplastic skin or mucous membrane is kept appropriate soft with outside elasticity, also there is prevention and treatment arthritis, antibacterial to disappear
Inflammation, anti-aging, antiallergy etc..
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to
Routine techniques carries out.
Kessazulen sodium sulfonate, chemical name：Isosorbide-5-Nitrae-dimethyl -7- isopropyl Azulene -3- sodium sulfonates, with stronger life
Object activity has antibacterial anti-inflammatory, anti-allergic effects and promotes function of tissue regeneration, because its is safe, in medicine, health products and change
The industries such as cosmetic are widely used, and especially create wound healing, promote significant effect in terms of regeneration.
Notogineng Extract chemical composition contain saponin, predominantly sanchinoside E1, Rg1, Rg2 and a small amount of panaxoside Ra,
There is dissipate stasis of blood hemostasis, removing toxicity for detumescence can be obviously promoted wound wound location blood circulation, be that wound epidermis is thin by Rb2, Rb and Re
Born of the same parents provide nutrition, accelerate granulation growth.
Silk tree bark has containing saponin, tannin etc., sweet in flavor and neutral in nature and solves strongly fragrant and blood, calming heart, and subduing inflammation and other effects is wound
Mouth subduing inflammation makes neoplastic skin or mucous membrane keep appropriate soft and elasticity.
Flos Campsis extract has cooling blood, expelling wind, cures mainly blood hot air wind producing, rubella itch, skin exudative dermatitis, in the wound healing phase
Between evacuate pathogenic wind it is antipruritic, improve human body to the anti-stress ability and immunity of external environment.
Embodiment 1
A kind of skin repair frost, includes the component of following mass percent：Skin repair composition 0.1%, ring five poly- two
Methylsiloxane 1%, caprylic/capric triglyceride 1%, double-PEG/PPG-16/16 PEG/PPG-16/16 polydimethylsiloxanes
Alkane 0.1%, dimethyl silicone polymer 1%, isononyl isononanoate 5%, rice (ORYZA SATIVA) oil extracted from rice husks 3%, glycerine polypropylene
Acid esters 1%, cetostearyl alcohol 3%, stearine 1%, PEG-100 stearates 1%, PEG-20 methyl times semihards
Resin acid ester 1%, Queensland nut (MACADAMIA TERNIFOLIA) seed oil 2%, oleyl alcohol eruciate 1%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) fruit fat 0.5%, sodium acrylate/sodium acryloyldimethyl taurate copolymers 0.1%, poly- mountain
The sub- oil of pears alcohol ester -600.1%, isohexadecane 0.1%, stearic acid 0.1%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization
Alcohol dimerized linoleic acid ester 0.1%, tocopherol acetate 0.1%, polyalcohol 5%, pyrenomycetes (SCLEROTIUM ROLFSSII) glue
0.1%, xanthans 0.05%, pectin 0.01%, carbomer 0.1%, dipotassium glycyrrhizinate 0.01%, arginine 0.1%, EDTA bis-
Sodium 0.01%, Sodium Hyaluronate 0.01%, Butylated Hydroxytoluene 0.01%, potassium sorbate 0.3%, water surplus.
The skin repair composition is by 0.1 part of Kessazulen sodium sulfonate, 10 parts of compositions of Notogineng Extract.
Embodiment 2
A kind of skin repair frost, includes the component of following mass percent：Skin repair composition 10%, five poly- diformazan of ring
Radical siloxane 5%, caprylic/capric triglyceride 8%, double-PEG/PPG-16/16 PEG/PPG-16/16 dimethyl silicone polymers
2%, dimethyl silicone polymer 5%, isononyl isononanoate 1%, rice (ORYZA SATIVA) oil extracted from rice husks 0.1%, glycerine polyacrylic acid
Ester 0.1%, cetostearyl alcohol 0.1%, stearine 0.1%, PEG-100 stearates 0.1%, PEG-20 methyls
Sesquistearate 0.1%, Queensland nut (MACADAMIA TERNIFOLIA) seed oil 0.1%, oleyl alcohol eruciate 0.1%, ox
Oily fruit tree (BUTYROSPERMUM PARKII) fruit fat 3%, sodium acrylate/sodium acryloyldimethyl taurate copolymers 0.6%,
Polysorbate -601%, isohexadecane 1%, stearic acid 1%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol
Dimerized linoleic acid ester 1%, tocopherol acetate 1%, polyalcohol 15%, pyrenomycetes (SCLEROTIUM ROLFSSII) glue 1%,
Xanthans 0.3%, pectin 0.3%, carbomer 0.5%, dipotassium glycyrrhizinate 0.3%, arginine 0.5%, EDETATE SODIUM 0.05%,
Sodium Hyaluronate 0.05%, Butylated Hydroxytoluene 0.1%, potassium sorbate 0.7%, water surplus.
The skin repair composition is by 10 parts of Kessazulen sodium sulfonate, 0.1 part of composition of Notogineng Extract.
Embodiment 3
A kind of skin repair frost, includes the component of following mass percent：Skin repair composition 5%, five poly- diformazan of ring
Radical siloxane 2.5%, caprylic/capric triglyceride 4.58%, double-PEG/PPG-16/16PEG/PPG-16/16 poly dimethyls silicon
It is oxygen alkane 1.1%, dimethyl silicone polymer 2.5%, isononyl isononanoate 2.5%, rice (ORYZA SATIVA) oil extracted from rice husks 1.6%, sweet
Oily polyacrylate 0.5%, cetostearyl alcohol 1.6%, stearine 0.5%, PEG-100 stearates 0.5%, PEG-
20 methyl sesquistearates 0.5%, Queensland nut (MACADAMIA TERNIFOLIA) seed oil 1.1%, oleyl alcohol erucic acid
Ester 0.5%, Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 1.7%, sodium acrylate/sodium acryloyldimethyl taurate
Copolymer 0.3%, polysorbate -600.5%, isohexadecane 0.5%, stearic acid 0.5%, double-docosyl alcohol/isooctadecanol/
Phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester 0.5%, tocopherol acetate 0.5%, polyalcohol 10%, pyrenomycetes
(SCLEROTIUM ROLFSSII) glue 0.5%, xanthans 0.15%, pectin 0.15%, carbomer 0.3%, dipotassium glycyrrhizinate
0.15%, arginine 0.3%, EDETATE SODIUM 0.03%, Sodium Hyaluronate 0.03%, Butylated Hydroxytoluene 0.05%, potassium sorbate
0.5%, water surplus.
The skin repair composition is by 5 parts of Kessazulen sodium sulfonate, 5 parts of compositions of Notogineng Extract.
Embodiment 4
A kind of skin repair frost, includes the component of following mass percent：Skin repair combination 2%, five poly dimethyl of ring
Siloxanes 2%, caprylic/capric triglyceride 2%, double-PEG/PPG-16/16PEG/PPG-16/16 dimethyl silicone polymers
0.5%, dimethyl silicone polymer 2%, isononyl isononanoate 2%, rice (ORYZA SATIVA) oil extracted from rice husks 0.6%, glycerine polypropylene
Acid esters 0.3%, cetostearyl alcohol 0.5%, stearine 0.2%, PEG-100 stearates 0.2%, PEG-20 methyl Portugal
Sugared sesquistearate 0.2%, Queensland nut (MACADAMIA TERNIFOLIA) seed oil 0.6%, oleyl alcohol eruciate 0.2%,
Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 0.8%, sodium acrylate/sodium acryloyldimethyl taurate copolymers
0.2%, polysorbate -600.3%, isohexadecane 0.2%, stearic acid 0.3%, double-docosyl alcohol/isooctadecanol/plant steroid
Alcohol dimerization Asia oleyl alcohol dimerized linoleic acid ester 0.3%, tocopherol acetate 0.2%, polyalcohol 7%, pyrenomycetes (SCLEROTIUM
ROLFSSII) glue 0.2%, xanthans 0.1%, pectin 0.1%, carbomer 0.2%, dipotassium glycyrrhizinate 0.1%, arginine
0.2%, EDETATE SODIUM 0.02%, Sodium Hyaluronate 0.02%, Butylated Hydroxytoluene 0.03%, benzyl alcohol 0.3%, water surplus.
The skin repair composition is by 2 parts of Kessazulen sodium sulfonate, 6 parts of Notogineng Extract, silk tree bark extract 0.1
Part, 10 parts of compositions of Flos Campsis extract.
Embodiment 5
A kind of skin repair frost, includes the component of following mass percent：Skin repair combination 7%, five poly dimethyl of ring
Siloxanes 3%, caprylic/capric triglyceride 6%, double-PEG/PPG-16/16 PEG/PPG-16/16 dimethyl silicone polymers
1.6%, dimethyl silicone polymer 4%, isononyl isononanoate 4%, rice (ORYZA SATIVA) oil extracted from rice husks 2%, glycerine polyacrylic acid
Ester 0.8%, cetostearyl alcohol 2%, stearine 0.8%, PEG-100 stearates 0.7%, PEG-20 methyls times
Semi-solid fat acid esters 0.8%, Queensland nut (MACADAMIA TERNIFOLIA) seed oil 0.9%, oleyl alcohol eruciate 0.7%, butter
Fruit tree (BUTYROSPERMUM PARKII) fruit fat 2.5%, sodium acrylate/sodium acryloyldimethyl taurate copolymers 0.5%,
Polysorbate -600.7%, isohexadecane 0.6%, stearic acid 0.8%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization
Sub- oleyl alcohol dimerized linoleic acid ester 0.6%, tocopherol acetate 0.7%, polyalcohol 12%, pyrenomycetes (SCLEROTIUM
ROLFSSII) glue 0.7%, xanthans 0.2%, pectin 0.2%, carbomer 0.4%, dipotassium glycyrrhizinate 0.2%, arginine
0.4%, EDETATE SODIUM 0.03%, Sodium Hyaluronate 0.04%, Butylated Hydroxytoluene 0.07%, potassium sorbate 0.3%, benzyl alcohol
0.1%, water surplus.
The skin repair composition is by 7 parts of Kessazulen sodium sulfonate, 3 parts of Notogineng Extract, silk tree bark extract 10
Part, 0.1 part of composition of Flos Campsis extract.
Embodiment 6
A kind of skin repair frost, includes the component of following mass percent：Skin repair combination 2%, five poly dimethyl of ring
Siloxanes 4%, caprylic/capric triglyceride 3%, double-PEG/PPG-16/16PEG/PPG-16/16 dimethyl silicone polymers
1%, dimethyl silicone polymer 2%, isononyl isononanoate 4%, rice (ORYZA SATIVA) oil extracted from rice husks 0.6%, glycerine polyacrylic acid
Ester 0.2%, cetostearyl alcohol 1%, stearine 0.3%, PEG-100 stearates 0.4%, PEG-20 methyls times
Semi-solid fat acid esters 0.6%, Queensland nut (MACADAMIA TERNIFOLIA) seed oil 0.8%, oleyl alcohol eruciate 0.2%, butter
Fruit tree (BUTYROSPERMUM PARKII) fruit fat 1.5%, sodium acrylate/sodium acryloyldimethyl taurate copolymers 0.3%,
Polysorbate -600.2%, isohexadecane 0.3%, stearic acid 0.6%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization
Sub- oleyl alcohol dimerized linoleic acid ester 0.4%, tocopherol acetate 0.4%, polyalcohol 7%, pyrenomycetes (SCLEROTIUM
ROLFSSII) glue 0.7%, xanthans 0.1%, pectin 0.2%, carbomer 0.4%, dipotassium glycyrrhizinate 0.2%, arginine
0.3%, EDETATE SODIUM 0.03%, Sodium Hyaluronate 0.02%, Butylated Hydroxytoluene 0.06%, potassium sorbate 0.6%, water surplus.
The skin repair composition is by 7 parts of Kessazulen sodium sulfonate, 3 parts of Notogineng Extract, silk tree bark extract 5
Part, 5 parts of compositions of Flos Campsis extract.
Comparative example 1
Difference lies in be not added with Kessazulen sodium sulfonate with embodiment 3.
Comparative example 2
Difference lies in be not added with Notogineng Extract with embodiment 3.
Comparative example 3
Difference lies in be not added with silk tree bark extract with embodiment 6.
Comparative example 4
Difference lies in be not added with Flos Campsis extract with embodiment 6.
Using effect is tested
In order to assess effect of skin repair frost of the present invention, product made from embodiment 1-6 and comparative example 1-4 is being volunteered
Person tests with it, and choosing every group of 20-30 Sui subject test 30, (each 15 of men and women, it is light that skin all has working principle
The wound mouth of micro-scrape), without skin or systemic disease history, and tested period do not smear any drug unrelated with experiment or
Person's cosmetics, to avoid mutual influence.Volunteer respectively uses 1 product sooner or later, and skin every square centimeter is produced using 1g
Product；Every morning carry out skin repair effect detection, be observed continuously one week use as a result, and make a record, as shown in table 1.1 week
After inquire each volunteer, it is mildly non-stimulated to feed back product.
1 test recording table of table
Observation can be seen that the skin repair frost that 1-6 of the embodiment of the present invention is provided using result has most triers
Have and preferably promotes regeneration, the effect of the healing rate of acceleration of wound mouth, and without finding that product generates stimulation to trier
Allergic phenomena.
Embodiment 1-3 and comparative example 1-2 comparisons as it can be seen that Kessazulen sodium sulfonate, Notogineng Extract are to promote regeneration,
The key component of accelerating wound healing effect, and Kessazulen sodium sulfonate, Notogineng Extract compound the effect of repair cream when sharing
It is just apparent, embody synergistic function.
Embodiment 4-6 is with embodiment 1-3 comparisons as it can be seen that the addition of silk tree bark extract, clouds flower extract is substantially improved
The skin repair frost is to creating speed of wound healing, significant effect；And comparative example 3-4 and embodiment 4-6 is compared as it can be seen that silk tree
Promotion effect can be just embodied when bark extract, Flos Campsis extract share, and have the function of synergy.
The anti-inflammatory test of skin：It observes by the naked eye, chooses skin and occurred the patient of inflammation phenomenon by bite by mosquitos, observation makes
Use effect.300 triers are chosen, in the identical environment of humidity, are divided into 10 groups, every group of 30 people, sooner or later respectively using 1 time, three
Test result is as shown in table 2 after it：
2 test recording table of table
| Project | Total number of persons | It is not relieved number | It is relieved number | Recovery from illness number |
| Embodiment 1 | 30 | 0 | 13 | 17 |
| Embodiment 2 | 30 | 0 | 16 | 14 |
| Embodiment 3 | 30 | 0 | 16 | 14 |
| Embodiment 4 | 30 | 0 | 2 | 28 |
| Embodiment 5 | 30 | 0 | 2 | 28 |
| Embodiment 6 | 30 | 0 | 1 | 29 |
| Comparative example 1 | 30 | 22 | 8 | 0 |
| Comparative example 2 | 30 | 22 | 8 | 0 |
| Comparative example 3 | 30 | 0 | 15 | 15 |
| Comparative example 4 | 30 | 0 | 15 | 15 |
Embodiment 1-3 is with comparative example 1-2 comparisons as it can be seen that Kessazulen sodium sulfonate, Notogineng Extract compounding are repaired when sharing
The antiphlogistic effects of frost are more obvious, and healing number is substantially improved, and embodies synergistic function.
Embodiment 4-6 is with embodiment 1-3 comparisons as it can be seen that anti-inflammatory after silk tree bark extract, Flos Campsis extract is added
Effect is further promoted, and recovery from illness number has promotion, has the function of synergy；And 4-6 pairs of comparative example 3-4 and embodiment
Than as it can be seen that can just embody promotion effect when silk tree bark extract, Flos Campsis extract share, there is synergistic work
With.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (5)
1. a kind of having effects that the skin care compositions of skin repair, which is characterized in that include the component of following parts by weight：Guaiaci lignum
0.1-10 parts of sodium azulenesulfonate, 0.1-10 parts of Notogineng Extract.
2. a kind of according to claim 1 having effects that the skin care compositions of skin repair, which is characterized in that the combination
Object further includes the component of following parts by weight：0.1-10 parts of silk tree bark extract, 0.1-10 parts of Flos Campsis extract.
3. the application according to claim 1 or 2 for having effects that the skin care compositions of skin repair in preparing cosmetics,
Wherein, the dosage with the skin care compositions of skin repair is the 0.1-10wt% of final products weight.
4. a kind of skin repair frost, which is characterized in that include each component of following mass percentage：Such as claims 1 or 2 institute
That states has effects that the skin care compositions 0.1-10%, ring five dimethyl silicone polymer 1-5%, caprylic/capric of skin repair are sweet
Three ester 1-8% of oil, double-PEG/PPG-16/16 PEG/PPG-16/16 dimethyl silicone polymers 0.1-2%, polydimethylsiloxanes
Alkane 1-5%, isononyl isononanoate 1-5%, rice (ORYZA SATIVA) oil extracted from rice husks 0.1-3%, glycerine polyacrylate 0.1-1%,
Cetostearyl alcohol 0.1-3%, stearine 0.1-1%, PEG-100 stearate 0.1-1%, PEG-20 methyl times
Semi-solid fat acid esters 0.1-1%, Queensland nut (MACADAMIA TERNIFOLIA) seed oil 0.1-2%, oleyl alcohol eruciate 0.1-
1%, Butyrospermum parkii (BUTYROSPERMUM PARKII) fruit fat 0.5-3%, sodium acrylate/sodium acryloyldimethyl taurate are total
Polymers 0.1-0.6%, -60 0.1-1% of polysorbate, isohexadecane 0.1-1%, stearic acid 0.1-1%, double-docosyl alcohol/
Isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester 0.1-1%, tocopherol acetate 0.1-1%, polyalcohol 5-
15%, pyrenomycetes (SCLEROTIUM ROLFSSII) glue 0.1-1%, xanthans 0.05-0.3%, pectin 0.01-0.3%, card
Wave nurse 0.1-0.5%, dipotassium glycyrrhizinate 0.01-0.3%, arginine 0.1-0.5%, EDETATE SODIUM 0.01-0.05%, hyalomitome
Sour sodium 0.01-0.05%, Butylated Hydroxytoluene 0.01-0.1%, water surplus.
5. skin repair frost according to claim 4, which is characterized in that the skin repair frost further includes 0.3-
The preservative of 0.7wt%, wherein the preservative is at least one of potassium sorbate, benzyl alcohol, Phenoxyethanol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810413504.4A CN108309869A (en) | 2018-04-29 | 2018-04-29 | It is a kind of to have effects that the skin care compositions of skin repair and its application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN109966210A (en) * | 2019-04-23 | 2019-07-05 | 清远市立道精细化工有限公司 | A kind of face maintenance composition, aerosol and preparation method thereof |
| CN110876742A (en) * | 2019-11-14 | 2020-03-13 | 广州家安化妆品有限公司 | Pharmaceutical composition for repairing skin injury and application thereof |
| CN111973636A (en) * | 2019-05-21 | 2020-11-24 | 王飞 | Anorectal gel and preparation method thereof |
| CN112638357A (en) * | 2018-08-23 | 2021-04-09 | 株式会社Lg生活健康 | Composition for promoting differentiation or proliferation of human adipose-derived stem cells |
| CN113413354A (en) * | 2021-06-24 | 2021-09-21 | 杭州友丽医疗科技(集团)有限公司 | Active dressing with wound surface repairing and/or barrier regenerating effects, application of active dressing and skin repairing BB cream |
| CN115554184A (en) * | 2022-10-21 | 2023-01-03 | 觅方(杭州)化妆品有限公司 | Method for delaying oxidation of sodium azulene sulfonate |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112638357A (en) * | 2018-08-23 | 2021-04-09 | 株式会社Lg生活健康 | Composition for promoting differentiation or proliferation of human adipose-derived stem cells |
| CN112638357B (en) * | 2018-08-23 | 2024-03-08 | 株式会社Lg生活健康 | Composition for promoting differentiation or proliferation of human fat-derived stem cells |
| CN109966210A (en) * | 2019-04-23 | 2019-07-05 | 清远市立道精细化工有限公司 | A kind of face maintenance composition, aerosol and preparation method thereof |
| CN109966210B (en) * | 2019-04-23 | 2021-11-23 | 清远市立道精细化工有限公司 | Facial repair composition, aerosol and preparation method thereof |
| CN111973636A (en) * | 2019-05-21 | 2020-11-24 | 王飞 | Anorectal gel and preparation method thereof |
| CN110876742A (en) * | 2019-11-14 | 2020-03-13 | 广州家安化妆品有限公司 | Pharmaceutical composition for repairing skin injury and application thereof |
| CN113413354A (en) * | 2021-06-24 | 2021-09-21 | 杭州友丽医疗科技(集团)有限公司 | Active dressing with wound surface repairing and/or barrier regenerating effects, application of active dressing and skin repairing BB cream |
| CN115554184A (en) * | 2022-10-21 | 2023-01-03 | 觅方(杭州)化妆品有限公司 | Method for delaying oxidation of sodium azulene sulfonate |
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