CN108295136A - A kind of asthma in children medicine and preparation method thereof - Google Patents
A kind of asthma in children medicine and preparation method thereof Download PDFInfo
- Publication number
- CN108295136A CN108295136A CN201810287153.7A CN201810287153A CN108295136A CN 108295136 A CN108295136 A CN 108295136A CN 201810287153 A CN201810287153 A CN 201810287153A CN 108295136 A CN108295136 A CN 108295136A
- Authority
- CN
- China
- Prior art keywords
- weight
- parts
- mixing
- decoction
- asthma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Insects & Arthropods (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A kind of asthma in children medicine of present invention offer and preparation method thereof, including 20~70 parts by weight of Chinese ephedra, 30~100 parts by weight of Radix Astragali, 20~80 parts by weight of Chinese gall, 30~60 parts by weight of jujube, 40~100 parts by weight of Radix Glycyrrhizae, 10~30 parts by weight of rde bean, compared with prior art, the present invention has following advantageous effect for 40~80 parts by weight of dried orange peel, 20~50 parts by weight of ardisia japonica and 1~5 parts by weight of auxiliary agent：Because the present invention is added to Chinese ephedra, Radix Astragali, Chinese gall, jujube, Radix Glycyrrhizae, rde bean, dried orange peel, ardisia japonica and auxiliary agent, and then effectively food materials are combined with Chinese medicine, pharmacological is good, and therapeutic effect is good, and cure rate is high.
Description
Technical field
The present invention is a kind of asthma in children medicine and preparation method thereof, belongs to field of traditional Chinese.
Background technology
Doctor thinks：Cough variant asthma（Cough Type Asthma）Also known as cough variant asthma（Cough
Variant asthma, CVA）, Gluser in 1972 reports the disease and is named as variant asthma for the first time, refers to chronic cough
It coughs as a kind of specific type asthma of main or only clinical manifestation.GINA（Global asthma prevention proposal）In be specifically identified to cough
Variant asthma is a kind of form of asthma, its pathophysiological change is as asthma, and continues Airway inflammatory response
With airway hyperreactivity.Bronchial asthma start morbidity when, 5%~6% be using persistent cough as cardinal symptom, it is multiple
Life is often irritable cough, is often misdiagnosed as bronchitis at this time in night or morning.The more typical asthma of age of onset is
Height, there are about 13% patient ages to be more than 50 years old, and female middle-aged is more common.And in the Childhood, cough may be the only of asthma
Symptom, even develops into a tendency of bronchial asthma, and the patient of hospital is also in rise appreciably.So, with regard to how to find
A kind of endo-medicine that can effectively treat asthma in children, is an urgent problem needed to be solved.
Invention content
In view of the deficienciess of the prior art, it is an object of the present invention to provide a kind of asthma in children medicine and its preparation sides
Method, to solve the problems mentioned in the above background technology.
To achieve the goals above, the present invention is to realize by the following technical solutions：A kind of asthma in children medicine
Object and preparation method thereof, in parts by weight, including 20~70 parts by weight of Chinese ephedra, 30~100 parts by weight of Radix Astragali, Chinese gall 20~80
Parts by weight, 30~60 parts by weight of jujube, 40~100 parts by weight of Radix Glycyrrhizae, 10~30 parts by weight of rde bean, 40~80 weight of dried orange peel
Part, 1~5 parts by weight of 20~50 parts by weight of ardisia japonica and auxiliary agent.
A kind of asthma in children medicine preparation method, includes the following steps：
（1）A selected amount of jujube, Radix Astragali and rde bean are taken, mixing is crushed by grinder after mixing, its particle diameter is made to reach
10um-30um；
（2）The water mixing for accounting for 1~2 times of amount of raw material total amount is added into gained mixed raw material, obtains material liquid；
（3）Dried orange peel is put into the water of 2~3 times of amounts of its weight, distills 3~7 hours, obtain slurries；
（4）Chinese ephedra, ardisia japonica and Radix Glycyrrhizae are mixed, then puts it into water and decocts twice, put it into 8~12 times of fiber crops
It in the water of yellow, ardisia japonica and Radix Glycyrrhizae total weight, impregnates 0.3~0.7 hour, then decocts 1.5~2.5 hours, filter to obtain mixing
Liquid and the mixing dregs of a decoction；The mixing dregs of a decoction after first time is decocted for the second time and step（3）The slurries of extraction merge, then by it
Mixture is put into the water of 6~10 times of total weight of the mixture, is carried out second and is decocted, after decocting 0.5~1.5 hour the
Admixing medical solutions after secondary decoction and the mixing dregs of a decoction；
（5）Merge the admixing medical solutions obtained after decocting twice and step（3）The slurries of extraction, to obtain new admixing medical solutions,
The mixing dregs of a decoction after second of decoction of separation；
（6）Virgin pulp liquid is concentrated under reduced pressure with to new admixing medical solutions, become relative density be 1.08~1.12% it is clear
Cream is handled by centrifuge, obtains centrifugate, and centrifugate is concentrated under reduced pressure, and 1~5 weight is then added in concentrate
The auxiliary agent of part carries out 48~72h of aerobic fermentation；
（7）Then stop ventilation, and continues 24~48h of anaerobic fermentation；
（8）Liquid is obtained after letting cool processing.
Further, the auxiliary agent is a kind of soluble starch, and content is 1~5 parts by weight.
Further, the centrifuge speed is 14000~18000r/min.
Further, the temperature of the aerobic fermentation is 20~40 DEG C, rotating speed is 100~150rpm.
Beneficial effects of the present invention：A kind of asthma in children medicine and preparation method thereof of the present invention, because the present invention adds
Added Chinese ephedra, Radix Astragali, Chinese gall, jujube, Radix Glycyrrhizae, rde bean, dried orange peel, ardisia japonica and auxiliary agent, and then effectively by food materials with
Chinese medicine is combined, and pharmacological is good, and therapeutic effect is good, and cure rate is high.
Specific implementation mode
To make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, with reference to
Specific implementation mode, the present invention is further explained.
The present invention provides a kind of technical solution：A kind of asthma in children medicine and preparation method thereof, in parts by weight, packet
Include 20~70 parts by weight of Chinese ephedra, 30~100 parts by weight of Radix Astragali, 20~80 parts by weight of Chinese gall, 30~60 parts by weight of jujube, Radix Glycyrrhizae
40~100 parts by weight, 10~30 parts by weight of rde bean, 40~80 parts by weight of dried orange peel, 20~50 parts by weight of ardisia japonica and auxiliary agent 1
~5 parts by weight.
A kind of asthma in children medicine preparation method, includes the following steps：
（1）A selected amount of jujube, Radix Astragali and rde bean are taken, mixing is crushed by grinder after mixing, its particle diameter is made to reach
10um-30um；
（2）The water mixing for accounting for 1~2 times of amount of raw material total amount is added into gained mixed raw material, obtains material liquid；
（3）Dried orange peel is put into the water of 2~3 times of amounts of its weight, distills 3~7 hours, obtain slurries；
（4）Chinese ephedra, ardisia japonica and Radix Glycyrrhizae are mixed, then puts it into water and decocts twice, put it into 8~12 times of fiber crops
It in the water of yellow, ardisia japonica and Radix Glycyrrhizae total weight, impregnates 0.3~0.7 hour, then decocts 1.5~2.5 hours, filter to obtain mixing
Liquid and the mixing dregs of a decoction；The mixing dregs of a decoction after first time is decocted for the second time and step（3）The slurries of extraction merge, then by it
Mixture is put into the water of 6~10 times of total weight of the mixture, is carried out second and is decocted, after decocting 0.5~1.5 hour the
Admixing medical solutions after secondary decoction and the mixing dregs of a decoction；
（5）Merge the admixing medical solutions obtained after decocting twice and step（3）The slurries of extraction, to obtain new admixing medical solutions,
The mixing dregs of a decoction after second of decoction of separation；
（6）Virgin pulp liquid is concentrated under reduced pressure with to new admixing medical solutions, become relative density be 1.08~1.12% it is clear
Cream is handled by centrifuge, obtains centrifugate, and centrifugate is concentrated under reduced pressure, and 1~5 weight is then added in concentrate
The auxiliary agent of part carries out 48~72h of aerobic fermentation；
（7）Then stop ventilation, and continues 24~48h of anaerobic fermentation；
（8）Liquid is obtained after letting cool processing.
Auxiliary agent is a kind of soluble starch, and content is 1~5 parts by weight, and centrifuge speed is 14000~18000r/
Min, the temperature of aerobic fermentation is 20~40 DEG C, rotating speed is 100~150rpm.
Embodiment 1：20 parts by weight of Chinese ephedra, 30 parts by weight of Radix Astragali, 20 parts by weight of Chinese gall, 30 parts by weight of jujube, Radix Glycyrrhizae 40
Parts by weight, 10 parts by weight of rde bean, 40 parts by weight of dried orange peel, 1 parts by weight of 20 parts by weight of ardisia japonica and auxiliary agent, by jujube, Radix Astragali
And rde bean, mixing is crushed by grinder after mixing, so that its particle diameter is reached 10um, is added and accounts for into gained mixed raw material
The water mixing of 1 times of amount of raw material total amount, obtains material liquid, dried orange peel is put into the water of 2 times of amounts of its weight, distills 3 hours, is starched
Chinese ephedra, ardisia japonica and Radix Glycyrrhizae are mixed, then put it into water and decoct twice by liquid, put it into 8 times of Chinese ephedras, short
It in tea and the water of Radix Glycyrrhizae total weight, impregnates 0.3 hour, then decocts 1.3 hours, filter to obtain admixing medical solutions and the mixing dregs of a decoction；The
The mixing dregs of a decoction after the secondary decoction by first time merge with slurries, are then mixed object and are put into 6 times of total weight of the mixture
Water in, carry out second and decoct, after decocting 0.5 hour decoct for second after admixing medical solutions and the mixing dregs of a decoction, merge two
The admixing medical solutions and slurries obtained after secondary decoction detach the mixing dregs of a decoction after decocting second to obtain new admixing medical solutions,
Virgin pulp liquid is concentrated under reduced pressure with to new admixing medical solutions, the clear cream that relative density is 1.08% is become, passes through centrifuge
Processing, obtains centrifugate, centrifugate is concentrated under reduced pressure, and the auxiliary agent of 1 parts by weight is then added in concentrate, carries out aerobic
Ferment 48h, then stops ventilation, and continue anaerobic fermentation for 24 hours, and liquid is obtained after letting cool processing.
Embodiment 2：40 parts by weight of Chinese ephedra, 60 parts by weight of Radix Astragali, 40 parts by weight of Chinese gall, 30 parts by weight of jujube, Radix Glycyrrhizae 70
Parts by weight, 10 parts by weight of rde bean, 50 parts by weight of dried orange peel, 2.5 parts by weight of 35 parts by weight of ardisia japonica and auxiliary agent, by jujube, Huang
Stilbene and rde bean crush mixing by grinder after mixing, so that its particle diameter is reached 15um, be added into gained mixed raw material
The water mixing for accounting for 1.5 times of amounts of raw material total amount, obtains material liquid, dried orange peel is put into the water of 2.5 times of amounts of its weight, distills 4 hours,
Slurries are obtained, Chinese ephedra, ardisia japonica and Radix Glycyrrhizae are mixed, then puts it into water and decocts twice, put it into 10 times of fiber crops
In the water of yellow, ardisia japonica and Radix Glycyrrhizae total weight, impregnates 0.5 hour, then decoct 1.5 hours, filter to obtain admixing medical solutions and mixing
The dregs of a decoction；The mixing dregs of a decoction after first time is decocted for the second time merge with slurries, are then mixed object and are put into 7 times of mixtures
It in the water of total weight, carries out second and decocts, obtain the admixing medical solutions after decocting and the mixing dregs of a decoction after decocting 0.8 hour second,
Merge the admixing medical solutions and slurries obtained after decocting twice, it is mixed after second of decoction of separation to obtain new admixing medical solutions
The dregs of a decoction are closed, virgin pulp liquid is concentrated under reduced pressure with to new admixing medical solutions, become the clear cream that relative density is 1.10%, are led to
Centrifuge processing is crossed, centrifugate is obtained, centrifugate is concentrated under reduced pressure, the auxiliary agent of 3 parts by weight is then added in concentrate,
Aerobic fermentation 60h is carried out, then stops ventilation, and continue anaerobic fermentation 35h, liquid is obtained after letting cool processing.
Embodiment 3：60 parts by weight of Chinese ephedra, 80 parts by weight of Radix Astragali, 60 parts by weight of Chinese gall, 50 parts by weight of jujube, Radix Glycyrrhizae 80
Parts by weight, 20 parts by weight of rde bean, 60 parts by weight of dried orange peel, 3.5 parts by weight of 40 parts by weight of ardisia japonica and auxiliary agent, by jujube, Huang
Stilbene and rde bean crush mixing by grinder after mixing, so that its particle diameter is reached 20um, be added into gained mixed raw material
The water mixing for accounting for 1.7 times of amounts of raw material total amount, obtains material liquid, dried orange peel is put into the water of 2.7 times of amounts of its weight, distills 5 hours,
Slurries are obtained, Chinese ephedra, ardisia japonica and Radix Glycyrrhizae are mixed, then puts it into water and decocts twice, put it into 11 times of fiber crops
It in the water of yellow, ardisia japonica and Radix Glycyrrhizae total weight, impregnates 0.6 hour, then decocts 2 hours, filter to obtain admixing medical solutions and mixing medicine
Slag, second first time is decocted after the mixing dregs of a decoction merge with slurries, being then mixed object, to be put into 8 times of mixtures total
It in the water of weight, carries out second and decocts, obtain the admixing medical solutions after decocting and the mixing dregs of a decoction after decocting 1 hour second, merge
The admixing medical solutions and slurries obtained after decocting twice, to obtain new admixing medical solutions, the mixing medicine after second of decoction of separation
Virgin pulp liquid is concentrated under reduced pressure slag with to new admixing medical solutions, become relative density be 1.11% clear cream, by from
Scheming is handled, and obtains centrifugate, centrifugate is concentrated under reduced pressure, the auxiliary agent of 4 parts by weight is then added in concentrate, is carried out
Aerobic fermentation 65h then stops ventilation, and continues anaerobic fermentation 40h, and liquid is obtained after letting cool processing.
Embodiment 4：70 parts by weight of Chinese ephedra, 90 parts by weight of Radix Astragali, 70 parts by weight of Chinese gall, 60 parts by weight of jujube, Radix Glycyrrhizae 90
Parts by weight, 25 parts by weight of rde bean, 70 parts by weight of dried orange peel, 4 parts by weight of 45 parts by weight of ardisia japonica and auxiliary agent, by jujube, Radix Astragali
And rde bean, mixing is crushed by grinder after mixing, so that its particle diameter is reached 25um, is added and accounts for into gained mixed raw material
The water mixing of 1.8 times of amounts of raw material total amount, obtains material liquid, dried orange peel is put into the water of 2.7 times of amounts of its weight, distills 6 hours, obtains
To slurries, Chinese ephedra, ardisia japonica and Radix Glycyrrhizae are mixed, then puts it into water and decocts twice, put it into 11.5 times of fiber crops
In the water of yellow, ardisia japonica and Radix Glycyrrhizae total weight, impregnates 0.65 hour, then decoct 2.3 hours, filter to obtain admixing medical solutions and mixing
The dregs of a decoction, the mixing dregs of a decoction after for the second time decocting first time merge with slurries, are then mixed object and are put into 9 times of mixtures
It in the water of total weight, carries out second and decocts, obtain the admixing medical solutions after decocting and the mixing dregs of a decoction after decocting 1.3 hours second,
Merge the admixing medical solutions and slurries obtained after decocting twice, it is mixed after second of decoction of separation to obtain new admixing medical solutions
The dregs of a decoction are closed, virgin pulp liquid is concentrated under reduced pressure with to new admixing medical solutions, become the clear cream that relative density is 1.115%, are led to
Centrifuge processing is crossed, centrifugate is obtained, centrifugate is concentrated under reduced pressure, the auxiliary agent of 4 parts by weight is then added in concentrate,
Aerobic fermentation 69h is carried out, then stops ventilation, and continue anaerobic fermentation 45h, liquid is obtained after letting cool processing.
Embodiment 5：70 parts by weight of Chinese ephedra, 100 parts by weight of Radix Astragali, 80 parts by weight of Chinese gall, 60 parts by weight of jujube, Radix Glycyrrhizae
100 parts by weight, 30 parts by weight of rde bean, 80 parts by weight of dried orange peel, 5 parts by weight of 50 parts by weight of ardisia japonica and auxiliary agent, by jujube, Huang
Stilbene and rde bean crush mixing by grinder after mixing, so that its particle diameter is reached 30um, be added into gained mixed raw material
The water mixing for accounting for 2 times of amounts of raw material total amount, obtains material liquid, dried orange peel is put into the water of 3 times of amounts of its weight, distills 7 hours, obtains
Chinese ephedra, ardisia japonica and Radix Glycyrrhizae are mixed, then put it into water and decoct twice by slurries, put it into 12 times of Chinese ephedras, short
It in the water of thamnolia vermicularia and Radix Glycyrrhizae total weight, impregnates 0.7 hour, then decocts 2.5 hours, filter to obtain admixing medical solutions and the mixing dregs of a decoction,
The mixing dregs of a decoction after first time is decocted for the second time merge with slurries, are then mixed object and are put into 10 times of mixture total weights
It in the water of amount, carries out second and decocts, obtain the admixing medical solutions after decocting and the mixing dregs of a decoction after decocting 1.5 hours second, merge
The admixing medical solutions and slurries obtained after decocting twice, to obtain new admixing medical solutions, the mixing medicine after second of decoction of separation
Virgin pulp liquid is concentrated under reduced pressure slag with to new admixing medical solutions, become relative density be 1.12% clear cream, by from
Scheming is handled, and obtains centrifugate, centrifugate is concentrated under reduced pressure, the auxiliary agent of 5 parts by weight is then added in concentrate, is carried out
Aerobic fermentation 72h then stops ventilation, and continues anaerobic fermentation 48h, and liquid is obtained after letting cool processing.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention, for this field skill
For art personnel, it is clear that invention is not limited to the details of the above exemplary embodiments, and without departing substantially from the present invention spirit or
In the case of essential characteristic, the present invention can be realized in other specific forms.Therefore, in all respects, should all incite somebody to action
Embodiment regards exemplary as, and is non-limiting, the scope of the present invention by appended claims rather than on state
Bright restriction, it is intended that including all changes that come within the meaning and range of equivalency of the claims in the present invention
It is interior.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiment being appreciated that.
Claims (5)
1. a kind of asthma in children medicine and preparation method thereof, in parts by weight, it is characterised in that：Including 20~70 weight of Chinese ephedra
Amount part, 30~100 parts by weight of Radix Astragali, 20~80 parts by weight of Chinese gall, 30~60 parts by weight of jujube, 40~100 parts by weight of Radix Glycyrrhizae,
10~30 parts by weight of rde bean, 40~80 parts by weight of dried orange peel, 1~5 parts by weight of 20~50 parts by weight of ardisia japonica and auxiliary agent.
2. a kind of asthma in children medicine preparation method according to claim 1, it is characterised in that include the following steps：
A selected amount of jujube, Radix Astragali and rde bean are taken, mixing is crushed by grinder after mixing, its particle diameter is made to reach
10um-30um；
The water mixing for accounting for 1~2 times of amount of raw material total amount is added into gained mixed raw material, obtains material liquid；
Dried orange peel is put into the water of 2~3 times of amounts of its weight, distills 3~7 hours, obtain slurries；
By Chinese ephedra, ardisia japonica and Radix Glycyrrhizae mix, then put it into water and decoct twice, put it into 8~12 times of Chinese ephedras,
In the water of ardisia japonica and Radix Glycyrrhizae total weight, impregnates 0.3~0.7 hour, then decoct 1.5~2.5 hours, filter to obtain admixing medical solutions
And the mixing dregs of a decoction；The mixing dregs of a decoction after first time is decocted for the second time and step（3）The slurries of extraction merge, and are then mixed
Object is put into the water of 6~10 times of total weight of the mixture, is carried out second and is decocted, and is obtained after decocting 0.5~1.5 hour second
Admixing medical solutions after decoction and the mixing dregs of a decoction；
Merge the admixing medical solutions obtained after decocting twice and step（3）The slurries of extraction, to obtain new admixing medical solutions, separation
The mixing dregs of a decoction after second of decoction；
Virgin pulp liquid is concentrated under reduced pressure with to new admixing medical solutions, becomes the clear cream that relative density is 1.08~1.12%,
It is handled by centrifuge, obtains centrifugate, centrifugate is concentrated under reduced pressure, 1~5 parts by weight are then added in concentrate
Auxiliary agent carries out 48~72h of aerobic fermentation；
Then stop ventilation, and continues 24~48h of anaerobic fermentation；
Liquid is obtained after letting cool processing.
3. a kind of asthma in children medicine according to claim 1 and preparation method thereof, it is characterised in that：The auxiliary agent
For a kind of soluble starch, and content is 1~5 parts by weight.
4. a kind of asthma in children medicine according to claim 1 and preparation method thereof, it is characterised in that：The centrifugation
Machine rotating speed is 14000~18000r/min.
5. a kind of asthma in children medicine according to claim 1 and preparation method thereof, it is characterised in that：It is described aerobic
The temperature of fermentation is 20~40 DEG C, rotating speed is 100~150rpm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810287153.7A CN108295136A (en) | 2018-04-03 | 2018-04-03 | A kind of asthma in children medicine and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810287153.7A CN108295136A (en) | 2018-04-03 | 2018-04-03 | A kind of asthma in children medicine and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108295136A true CN108295136A (en) | 2018-07-20 |
Family
ID=62848037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810287153.7A Pending CN108295136A (en) | 2018-04-03 | 2018-04-03 | A kind of asthma in children medicine and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108295136A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6256435A (en) * | 1985-09-05 | 1987-03-12 | Tsumura Juntendo Inc | Coronary vasodilator |
| CN1947754A (en) * | 2006-10-23 | 2007-04-18 | 北京羚锐伟业科技有限公司 | Medicine for treating infantile asthma and its prepn. method |
| CN103099877A (en) * | 2013-02-07 | 2013-05-15 | 陈霞 | Traditional Chinese medicine formula for treating and preventing children asthmatic disease |
| CN105266010A (en) * | 2015-11-25 | 2016-01-27 | 农杰 | Instant powder for preventing and treating cough and asthma and preparation method of instant powder |
| CN105535087A (en) * | 2014-11-03 | 2016-05-04 | 郝纪涛 | Traditional Chinese medicinal formula for treating asthma |
| CN107158195A (en) * | 2017-07-23 | 2017-09-15 | 芦建华 | It is a kind of to treat pharmaceutical composition of children's bronchus asthma and preparation method thereof |
-
2018
- 2018-04-03 CN CN201810287153.7A patent/CN108295136A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6256435A (en) * | 1985-09-05 | 1987-03-12 | Tsumura Juntendo Inc | Coronary vasodilator |
| CN1947754A (en) * | 2006-10-23 | 2007-04-18 | 北京羚锐伟业科技有限公司 | Medicine for treating infantile asthma and its prepn. method |
| CN103099877A (en) * | 2013-02-07 | 2013-05-15 | 陈霞 | Traditional Chinese medicine formula for treating and preventing children asthmatic disease |
| CN105535087A (en) * | 2014-11-03 | 2016-05-04 | 郝纪涛 | Traditional Chinese medicinal formula for treating asthma |
| CN105266010A (en) * | 2015-11-25 | 2016-01-27 | 农杰 | Instant powder for preventing and treating cough and asthma and preparation method of instant powder |
| CN107158195A (en) * | 2017-07-23 | 2017-09-15 | 芦建华 | It is a kind of to treat pharmaceutical composition of children's bronchus asthma and preparation method thereof |
Non-Patent Citations (8)
| Title |
|---|
| 刘贵云等: "治喘伏贴灵对实验小鼠的抗炎及免疫作用的研究", 《湖南中医学院学报》 * |
| 宝成: "《家庭医生》", 30 April 2004, 中医古籍出版社 * |
| 张剑祥: ""冬病夏治"哮喘", 《医学文选》 * |
| 李四端: "防治哮喘有良方", 《家庭医学》 * |
| 毛水泉: "浅淡膏方"治未病"的临床体会", 《中华中医药杂志》 * |
| 沈燕君: "膏滋药治疗喘证56例疗效观察", 《浙江中医学院学报》 * |
| 牛坤香等: "五倍子治疗哮喘26例", 《中国民间疗法》 * |
| 陈梁等: "扶正化痰方对哮喘豚鼠肺组织相关微量元素的影响", 《中国医药学报》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101199595A (en) | Extractive process of baical skullcap root active ingredient | |
| CN102283935A (en) | Preparation method of herba leonuri and longan paste | |
| CN106173642A (en) | One is relieved inflammation or internal heat skin care Fructus Trichosanthis juice and preparation method thereof | |
| CN107875196A (en) | Complex enzyme, extract solution system, medicament, extract and preparation method thereof, application | |
| CN105707326A (en) | Preparation method of purple grass and juncus effuses instant tea powder | |
| CN106306247A (en) | Preparing method for girald pteroxygonum root composite tea | |
| CN108295136A (en) | A kind of asthma in children medicine and preparation method thereof | |
| CN105995920A (en) | Processing method of Japanese thistle herb root composite soy sauce | |
| CN103127390B (en) | Compound blood sugar reducing jewel orchid submicron powder and preparation method thereof | |
| CN100484962C (en) | Method for preparing Codonopsis pilosula polysaccharide extractive as Codonopsis pilosula active ingredient | |
| CN102319358B (en) | Preparation method of kidney-tonifying and life-prolonging capsule | |
| CN103549588A (en) | Preparation method for blueberry and health-care red date beverage | |
| CN105995822A (en) | Traditional Chinese medicine health-care blender prepared from green tea extract compounded with honey and preparation method of traditional Chinese medicine health-care blender | |
| CN111956715A (en) | Medicine for treating alcoholic liver disease and preparation method thereof | |
| CN105456809A (en) | Traditional Chinese medicine composition for treating hypertension, hyperglycemia and hyperlipidemia | |
| CN104798964A (en) | Momordica grosvenori and gynostemma pentaphylla tea | |
| CN1062154C (en) | Method for producing Chinese patent medicine for curing diabetes and its pill | |
| CN111184779A (en) | Preparation method of lung-purging granules containing semen lepidii and Chinese date | |
| CN111150811A (en) | Formula of blood sugar reducing powder | |
| CN107823912A (en) | A kind of method that Chinese herbal and crude drugs preparations is extracted using membrane separation technique | |
| CN108578554A (en) | A kind of spraying agent for ulcer of oral cavity and preparation method thereof | |
| CN104274607A (en) | Traditional Chinese medicine lipid-lowering compound preparation and preparation method thereof | |
| CN106389592A (en) | Preparation method and application of rhodiola rosea and coffee extract | |
| CN106343097A (en) | Novel radix-notoginseng healthy drink | |
| CN106108009A (en) | Herba Cirsii extracting solution, health product containing Herba Cirsii active component and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180720 |