CN108291216B - 用于治疗补体介导的疾病的组合物和方法 - Google Patents

用于治疗补体介导的疾病的组合物和方法 Download PDF

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CN108291216B
CN108291216B CN201680064219.5A CN201680064219A CN108291216B CN 108291216 B CN108291216 B CN 108291216B CN 201680064219 A CN201680064219 A CN 201680064219A CN 108291216 B CN108291216 B CN 108291216B
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vector
variant
complement
aav
expression
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CN108291216A (zh
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宋文超
D.古利帕利
三轮隆史
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University of Pennsylvania Penn
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14171—Demonstrated in vivo effect

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CN201680064219.5A 2015-09-24 2016-09-23 用于治疗补体介导的疾病的组合物和方法 Active CN108291216B (zh)

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US201562232008P 2015-09-24 2015-09-24
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PCT/US2016/053347 WO2017053732A2 (en) 2015-09-24 2016-09-23 Composition and method for treating complement-mediated disease

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US (4) US10988519B2 (https=)
EP (1) EP3359663A4 (https=)
JP (4) JP7261583B2 (https=)
KR (1) KR102773865B1 (https=)
CN (2) CN108291216B (https=)
AU (3) AU2016326627B2 (https=)
CA (1) CA2999299A1 (https=)
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GB201706808D0 (en) * 2017-04-28 2017-06-14 Univ Newcastle Modified complement proteins and uses thereof
CN111788311A (zh) * 2017-10-20 2020-10-16 双子治疗公司 用于治疗年龄相关性黄斑变性的组合物和方法
GB201800620D0 (en) 2018-01-15 2018-02-28 Univ Manchester C3b Binding Polypeptide
KR20210131309A (ko) * 2018-12-12 2021-11-02 플래그쉽 파이어니어링 이노베이션스 브이, 인크. 분비형 치료 양식을 운반하기 위한 아넬로좀
GB201821082D0 (en) * 2018-12-21 2019-02-06 Gyroscope Therapeutics Ltd Combination of complement factors i and h, and vector encoding thereof
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CA3158517A1 (en) * 2019-10-22 2021-04-29 Applied Genetic Technologies Corporation Adeno-associated virus (aav)vectors for the treatment of age-related macular degeneration and other ocular diseases and disorders
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US20210171592A1 (en) 2021-06-10
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US10988519B2 (en) 2021-04-27
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IL258024B2 (en) 2023-03-01
IL258024B (en) 2022-11-01
KR20180055872A (ko) 2018-05-25
AU2016326627A1 (en) 2018-04-05
CN115976105A (zh) 2023-04-18
CA2999299A1 (en) 2017-03-30
US20190177381A1 (en) 2019-06-13
AU2026201080A1 (en) 2026-03-05
CN108291216A (zh) 2018-07-17
WO2017053732A3 (en) 2017-05-11
US12180254B1 (en) 2024-12-31
AU2023201582B2 (en) 2025-11-13
IL296929B1 (en) 2025-03-01
RU2018114907A3 (https=) 2020-02-26
WO2017053732A2 (en) 2017-03-30
EP3359663A4 (en) 2019-08-14
IL296929B2 (en) 2025-07-01
AU2016326627B2 (en) 2022-12-15
RU2727411C2 (ru) 2020-07-21
HK1251482A1 (zh) 2019-02-01
IL258024A (en) 2018-05-31
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JP2018527941A (ja) 2018-09-27

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