CN108272960A - A kind of Chinese medicine composition for treating hemorrhoid disease and preparation method thereof and purposes - Google Patents
A kind of Chinese medicine composition for treating hemorrhoid disease and preparation method thereof and purposes Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition for treating hemorrhoid disease and preparation method thereof and purposes, it is made of the bulk pharmaceutical chemicals of following weight proportion：10~20 parts of rheum officinale, 10~20 parts of the coptis, 12~20 parts of radix scutellariae, 23~35 parts of frankincense, 20~38 parts of myrrh, 6~14 parts of Radix Angelicae Sinensis, 6~14 parts of Radix Salviae Miltiorrhizae, 23~40 parts of saltcake, 10~20 parts of Chinese gall, 10~20 parts of bletilla, 6~14 parts of alum, 3~7 parts of borneol.Chinese medicine composition of the present invention is significant in efficacy to hemorrhoid patient, and toxic side effect is small, and preparation process is simple, easy to use, the unique advantage with external application quick acting and preferable potential applicability in clinical practice.
Description
Technical field
The invention belongs to tcm fields, and in particular to a kind of Chinese medicine composition for treating hemorrhoid disease and preparation method thereof with
On the way.
Background technology
Hemorrhoid disease is a kind of common disease influencing human health, and incidence is high, and symptom is apparent, painful larger, cardinal symptom
It has blood in stool, pain, abjection, merocrine secretion's object increase with difficult defecation etc..Pathogenic factor is since yin-Yang is lacked of proper care, in addition outside
Wind, heat, dry, wet heresy are felt, caused by the factors such as seven feelings of the internal injury six external factors which cause diseases.
The common method of hemorrhoid disease treatment is all by drug administration decoction, suppository, ointment or operation, due to operation excision pain
It is bitter larger, meanwhile, the pharmaceutical preparation for the treatment of hemorrhoid disease can not meet clinical needs on the market at present, and therefore, there is an urgent need for a kind of effective
The external preparation of hemorrhoid disease is treated to treat this disease, improves patients ' life quality.
Invention content
The purpose of the present invention is to provide a kind of Chinese medicine composition for treating hemorrhoid disease and preparation method thereof and purposes.
The present invention provides a kind of Chinese medicine compositions, it is prepared by the bulk pharmaceutical chemicals of following weight proportion：
10~20 parts of rheum officinale, 10~20 parts of the coptis, 12~20 parts of radix scutellariae, 23~35 parts of frankincense, 20~38 parts of myrrh, Radix Angelicae Sinensis
6~14 parts, 6~14 parts of Radix Salviae Miltiorrhizae, 23~40 parts of saltcake, 10~20 parts of Chinese gall, 10~20 parts of bletilla, 6~14 parts of alum, borneol
3~7 parts.
Preferably, it is prepared by the bulk pharmaceutical chemicals of following weight proportion：
12~17 parts of rheum officinale, 12~18 parts of the coptis, 14~18 parts of radix scutellariae, 25~33 parts of frankincense, 25~35 parts of myrrh, Radix Angelicae Sinensis
8~12 parts, 8~12 parts of Radix Salviae Miltiorrhizae, 25~35 parts of saltcake, 12~18 parts of Chinese gall, 12~18 parts of bletilla, 8~12 parts of alum, borneol
4~6 parts.
It is further preferred that it is prepared by the bulk pharmaceutical chemicals of following weight proportion：
15 parts of rheum officinale, 15 parts of the coptis, 15 parts of radix scutellariae, 30 parts of frankincense, 30 parts of myrrh, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Salviae Miltiorrhizae, saltcake 30
Part, 15 parts of Chinese gall, 15 parts of bletilla, 10 parts of alum, 5 parts of borneol.
The Chinese medicine composition is with the rheum officinale, coptis, radix scutellariae, frankincense, myrrh, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, saltcake, Chinese gall, white
And crude drug, water extract or the extractive with organic solvent of alum, borneol are active constituent, in addition pharmaceutically acceptable auxiliary
Preparation is prepared in material.
Further, the preparation is external preparation.
Further, the external preparation is lotion, plastics, liniment, paste, decoction, powder, ointment, aerosol
Or spray.
Preferably, the external preparation is lotion.
The present invention provides a kind of methods preparing the Chinese medicine composition, it includes the following steps：
(1) bulk pharmaceutical chemicals of each weight proportion are weighed；
(2) dry, pulverize, sieving to get.
Wherein, in step (2), the sieving was 120 mesh sieve.
Purposes of the Chinese medicine composition in the drug for preparing treatment hemorrhoid disease.
Preferably, the hemorrhoid disease is internal piles, external piles or mixed hemorrhoid.
Chinese medicine composition of the present invention is by the rheum officinale, coptis, radix scutellariae, frankincense, myrrh, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, saltcake, Chinese gall, white
And alum, 12 herbal medicine of borneol composition.
We close Huoluo Xiaoling Dan by Xiexin Tang and add and subtract.《Plain Questions is to will very discuss greatly》It says:" all sufferings sores, all belong to
In the heart ", rheum officinale, the coptis, radix scutellariae are clearing heat and detoxicating in side, and sore, swelling and pain relieving are treated in removing the heart-fire；Frankincense, myrrh, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae name are said " living
Network Xiaolingdan pill " promoting blood circulation, removes obstruction in channels to relieve pain；Saltcake softening and resolving hard mass, Chinese gall hemostasis, astringing and avoiding visceroptosis；Bletilla astringing to arrest bleeding, detumescence
Myogenic；Alum eliminating dampness is stopped blooding；Swelling and pain relieving, heat-clearing dissipates poison.All medicines share, play altogether clearing heat and promoting diuresis, sore hemostasis, swelling and pain relieving it
Effect.
Chinese medicine composition of the present invention is significant in efficacy to hemorrhoid patient, and toxic side effect is small, and preparation process is simple, easy to use,
Unique advantage with external application quick acting and preferable potential applicability in clinical practice.
The above according to the present invention, according to the ordinary technical knowledge and customary means of relevant art, not
It is detached under the premise of the above-mentioned basic fundamental thought of the present invention, the modification, replacement or change of other diversified forms can also be made.
The specific implementation mode of form by the following examples remakes further specifically the above of the present invention
It is bright.But the range that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to example below.It is all to be based on the above of the present invention
The technology realized all belongs to the scope of the present invention.
Specific implementation mode
The preparation of 1 Chinese medicine composition of the present invention of embodiment
1. raw material：Rheum officinale 15g, coptis 15g, radix scutellariae 15g, frankincense 30g, myrrh 30g, Radix Angelicae Sinensis 10g, Radix Salviae Miltiorrhizae 10g, saltcake
30g, Chinese gall 15g, bletilla 15g, alum 10g, borneol 5g.
2. preparation method：Bulk pharmaceutical chemicals are weighed by above-mentioned weight proportion；Crush be smalls, cross 120 mesh sieve to get.
The preparation of 2 Chinese medicine composition of the present invention of embodiment
1. raw material：Rheum officinale 17g, coptis 18g, radix scutellariae 20g, frankincense 35g, myrrh 35g, Radix Angelicae Sinensis 14g, Radix Salviae Miltiorrhizae 12g, saltcake
35g, Chinese gall 18g, bletilla 18g, alum 12g, borneol 7g.
2. preparation method：Bulk pharmaceutical chemicals are weighed by above-mentioned weight proportion；With embodiment 1.
The preparation of 3 Chinese medicine composition of the present invention of embodiment
1. raw material：Rheum officinale 12g, coptis 12g, radix scutellariae 12g, frankincense 23g, myrrh 25g, Radix Angelicae Sinensis 6g, Radix Salviae Miltiorrhizae 8g, saltcake 23g,
Chinese gall 12g, bletilla 10g, alum 8g, borneol 3g.
2. preparation method：Bulk pharmaceutical chemicals are weighed by above-mentioned weight proportion；With embodiment 1.
The preparation of 4 Chinese medicine composition of the present invention of embodiment
1. raw material：Rheum officinale 20g, coptis 20g, radix scutellariae 18g, frankincense 33g, myrrh 38g, Radix Angelicae Sinensis 12g, Radix Salviae Miltiorrhizae 14g, saltcake
40g, Chinese gall 20g, bletilla 20g, alum 14g, borneol 6g.
2. preparation method：Bulk pharmaceutical chemicals are weighed by above-mentioned weight proportion；With embodiment 1.
The preparation of 5 Chinese medicine composition of the present invention of embodiment
1. raw material：Rheum officinale 10g, coptis 10g, radix scutellariae 14g, frankincense 25g, myrrh 20g, Radix Angelicae Sinensis 8g, Radix Salviae Miltiorrhizae 6g, saltcake 25g,
Chinese gall 10g, bletilla 12g, alum 6g, borneol 4g.
2. preparation method：Bulk pharmaceutical chemicals are weighed by above-mentioned weight proportion；With embodiment 1.
Beneficial effects of the present invention are proved below by way of specific clinical test.
The clinical efficacy of 1 present composition of test example
1, clinical data
The group selection mixed hemorrhoid patient 50 that 1~December in 2017, this Out-patient Department was accepted for medical treatment is tested, all patients are by inspection
It looks into and is diagnosed as mixed hemorrhoid.Man 26, female 24；25~65 years old age, average age (38.25 ± 10.15) year.
1.1 diagnostic criteria：
This disease is with reference to anal intestine branch of China Association of Traditional Chinese Medicine in 2006, surgery branch of Chinese Medical Association Colon and rectum anus
The hemorrhoid disease diagnostic criteria that surgery group, Chinese Association of Chinese and Western Medicine large intestine anal disease Professional Committee formulate is diagnosed.
1, internal piles
Main clinical manifestation is bleeding and abjection, can concurrent thrombus, incarceration, strangulation and difficult defecation.According to the disease of internal piles
Shape, its severity are divided into 4 degree.
I degree：When just band blood, bleed, bleeding after an action of the bowels can voluntarily stop；No hemorrhoid abjection.
II degree：Often have blood in stool；There is hemorrhoid abjection when defecation, voluntarily can also receive after an action of the bowels.
III degree：It can have blood in stool；There is hemorrhoid abjection when defecation or long station and cough, fatigue, heavy burden, need to also be received with hand.
IV degree：It can have blood in stool；Easily abjection after hemorrhoid are persistently deviate from or also received.
2, external piles
Main clinical manifestation is podex soft tissue agglomerate, has uncomfortable anus, humidity itch or foreign body sensation, thrombus such as occurs
And inflammation can have pain.
3, mixed hemorrhoid
Main clinical manifestation exists simultaneously for the symptom of internal piles and external piles, and Hemorrhoids are shown as when serious.
1.2 inclusion criteria
The case for meeting 1.1 section diagnostic criteria is included in.
2, therapy
Experimental group：Give the drug of the embodiment of the present invention 1.
Specifically medication is：
800ml boiling water is added, wherein the volume mass of boiling water and drug powder ratio is in the drug powder of Example 1
800：100mL/g impregnates thermophilic hip bath 15 minutes after ten minutes, twice a day.The suitable 100 grams of lifes of weight of the drug impregnated every time
Medicine.
3, observation of curative effect
3.1 criterion of therapeutical effect：
(1) it fully recovers：Symptom (have blood in stool, deviate from or pain) disappears, and checks that hemorrhoid have disappeared.
(2) it improves：Symptom is obviously improved after treatment, checks that hemorrhoid have been obviously reduced.
(3) invalid：Symptom and form have no difference to that before treatment.
3.2 treatment results
As shown in table 1：
| Group | Recovery from illness | It improves | In vain | Cure rate | It is efficient |
| Experimental group (50 people) | 20 | 30 | 0 | 40% | 100% |
Experiment conclusion：50 patients that the present invention is treated fully recover 20, improve 30, cure rate reaches 40%, effectively
Rate reaches 100%, the results showed that, Chinese medicine preparation reasonable recipe of the present invention is significant in efficacy to hemorrhoid disease, is worth clinical application.
4, model case
4.1 classical cases 1
Zhang, man, 48 years old, the swollen object abjection of anus 3 years, aggravated to seek medical advice with 1 Zhou Lai our hospital outpatient service of having blood in stool repeatedly.
Symptoms include：The swollen object abjection of anus, rectal tenesmus pain, no scratchiness, without tenesmus, no chilly fever, no abdominal pain
Diarrhea, sleep is poor, and diet is poor, and urine is normal, and stool discharge is unsmooth, 1-2 times/day.Mixed hemorrhoid is diagnosed as with blood through training inspection
Bolt type external piles.
Therapy：The drug and preparation method for giving the embodiment of the present invention 1 take 100g fine powders, and 800ml boiling water is added,
Thermophilic hip bath 15 minutes after ten minutes are impregnated, once in the morning and once at night, continuous treatment 2 weeks.Curative effect：Patient treat 2 weeks after have blood in stool,
Abjection and pain disappear, clinical cure.
In conclusion Chinese medicine composition of the present invention is significant in efficacy to hemorrhoid patient, toxic side effect is small, and preparation process is simple,
It is easy to use, the unique advantage with external application quick acting and preferable potential applicability in clinical practice.
Claims (10)
1. a kind of Chinese medicine composition, it is characterised in that：It is prepared by the bulk pharmaceutical chemicals of following weight proportion：
10~20 parts of rheum officinale, 10~20 parts of the coptis, 12~20 parts of radix scutellariae, 23~35 parts of frankincense, 20~38 parts of myrrh, Radix Angelicae Sinensis 6~
14 parts, 6~14 parts of Radix Salviae Miltiorrhizae, 23~40 parts of saltcake, 10~20 parts of Chinese gall, 10~20 parts of bletilla, 6~14 parts of alum, borneol 3~
7 parts.
2. Chinese medicine composition according to claim 1, it is characterised in that：It is prepared by the bulk pharmaceutical chemicals of following weight proportion
It forms：
12~17 parts of rheum officinale, 12~18 parts of the coptis, 14~18 parts of radix scutellariae, 25~33 parts of frankincense, 25~35 parts of myrrh, Radix Angelicae Sinensis 8~
12 parts, 8~12 parts of Radix Salviae Miltiorrhizae, 25~35 parts of saltcake, 12~18 parts of Chinese gall, 12~18 parts of bletilla, 8~12 parts of alum, borneol 4~
6 parts.
3. Chinese medicine composition according to claim 2, it is characterised in that：It is prepared by the bulk pharmaceutical chemicals of following weight proportion
It forms：
15 parts of rheum officinale, 15 parts of the coptis, 15 parts of radix scutellariae, 30 parts of frankincense, 30 parts of myrrh, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Salviae Miltiorrhizae, 30 parts of saltcake,
15 parts of Chinese gall, 15 parts of bletilla, 10 parts of alum, 5 parts of borneol.
4. according to the Chinese medicine composition described in claims 1 to 3 any one, it is characterised in that：It is with rheum officinale, the coptis, Huang
A kind of reed mentioned in ancient books, frankincense, myrrh, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, saltcake, Chinese gall, bletilla, alum, the crude drug of borneol, water extract or organic solvent
Extract is active constituent, in addition preparation is prepared in pharmaceutically acceptable auxiliary material.
5. Chinese medicine composition according to claim 4, it is characterised in that：The preparation is external preparation.
6. Chinese medicine composition according to claim 5, it is characterised in that：The external preparation is lotion, plastics, puts on the skin
Agent, paste, decoction, powder, ointment, aerosol or spray.
7. Chinese medicine composition according to claim 6, it is characterised in that：The external preparation is lotion.
8. a kind of method preparing the Chinese medicine composition described in claim 1~7 any one, it is characterised in that：It includes such as
Lower step：
(1) bulk pharmaceutical chemicals of each weight proportion are weighed；
(2) dry, pulverize, sieving to get.
Preferably, in step (2), the sieving was 120 mesh sieve.
9. purposes of the Chinese medicine composition in the drug for preparing treatment hemorrhoid disease described in claim 1~7 any one.
10. purposes according to claim 9, it is characterised in that：The hemorrhoid disease is internal piles, external piles or mixed hemorrhoid.
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| CN201810272996.XA CN108272960B (en) | 2018-03-29 | 2018-03-29 | Traditional Chinese medicine composition for treating hemorrhoidal disease and preparation method and application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113577195A (en) * | 2021-08-02 | 2021-11-02 | 湖州市妇幼保健院 | Medicine for treating haemorrhoids of pregnant women, use method and application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060033070A (en) * | 2004-10-14 | 2006-04-19 | 김태균 | Hip-bath compositions for treatment of herorrhoids or gynecological diseases, and hip-bath bag containing it |
| CN102370815A (en) * | 2010-08-11 | 2012-03-14 | 郁锋 | Hemorrhoid external treatment powder |
| CN105233180A (en) * | 2015-11-16 | 2016-01-13 | 庄小侃 | Drug for treating internal hemorrhoid due to damp-heat pouring downward syndrome |
-
2018
- 2018-03-29 CN CN201810272996.XA patent/CN108272960B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060033070A (en) * | 2004-10-14 | 2006-04-19 | 김태균 | Hip-bath compositions for treatment of herorrhoids or gynecological diseases, and hip-bath bag containing it |
| CN102370815A (en) * | 2010-08-11 | 2012-03-14 | 郁锋 | Hemorrhoid external treatment powder |
| CN105233180A (en) * | 2015-11-16 | 2016-01-13 | 庄小侃 | Drug for treating internal hemorrhoid due to damp-heat pouring downward syndrome |
Non-Patent Citations (2)
| Title |
|---|
| 徐琰: "活络效灵丹加味坐浴治疗痔54例", 《黑龙江医药》 * |
| 董耀林: "加味四黄膏治疗肛门急性炎症253例", 《中国农村医学》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113577195A (en) * | 2021-08-02 | 2021-11-02 | 湖州市妇幼保健院 | Medicine for treating haemorrhoids of pregnant women, use method and application |
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