CN108272850A - A kind of thrombolytic drug and preparation method thereof - Google Patents
A kind of thrombolytic drug and preparation method thereof Download PDFInfo
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- CN108272850A CN108272850A CN201810376119.7A CN201810376119A CN108272850A CN 108272850 A CN108272850 A CN 108272850A CN 201810376119 A CN201810376119 A CN 201810376119A CN 108272850 A CN108272850 A CN 108272850A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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Abstract
The invention discloses a kind of thrombolytic drugs and preparation method thereof, include the component of following parts by weight：15~25 parts of ganoderma lucidum, 20~30 parts of field thistle, 20~30 parts of oyster, 3~6 parts of pearl sand, 20~30 parts of pearl, 10~20 parts of honeysuckle.The invention belongs to technical field of traditional Chinese medicines, the present invention prepares the thrombolytic drug that a kind of thrombolytic effect is notable, of low cost, without any side effects, convenient to take, cure rate is high by selecting suitable natural Chinese traditional medicines material and its proportioning.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, in particular to a kind of thrombolytic drug and preparation method thereof.
Background technology
With increasingly raising, the change of dietary structure of living standards of the people, suffering from thrombotic diseases, person is significantly increased, such as：
Coronary heart disease, blood is thick, headache, dizziness, cerebral thrombus, brain tumor etc., above-mentioned disease to the life of patient and its family members bring it is many not
Just and it is greatly worried, or even the life of patient is caused greatly to threaten.It has been investigated that above-mentioned illness one is taken the photograph with sodium
It is related to enter amount, causes capillary to harden and then generates illness；Second is that with scaring, easily angry, short-tempered related.Though currently,
So existing some drugs have certain short term effect to the treatment of the disease, but curative effect is very low, and therapeutic effect is not satisfactory, and this
A little drugs are mostly Western medicine, or need to rely on external bypass surgery, many patients because Western medicine or operation high expensive, side effect compared with
It cannot adhere to treating greatly.Chinese herbal medicine is the national rarity in China, develop be Chinese medicine worker responsibility.Whether can lead to
After experience of practising medicine for many years, summary prepares one kind using Chinese herbal medicine as raw material, cheap, curative effect is prominent, has no toxic side effect
The drug for treating thrombotic diseases, is exactly that there is an urgent need for the projects of research by current Chinese medicine worker.
Invention content
To solve above-mentioned existing problem, the present invention prepares one by selecting suitable natural Chinese traditional medicines material and its proportioning
Kind thrombolytic effect notable, of low cost, without any side effects, convenient to take, cure rate is high thrombolytic drug and its preparation side
Method.
The technical solution adopted by the present invention is as follows：A kind of thrombolytic drug includes the component of following parts by weight：Ganoderma lucidum 15~25
Part, 20~30 parts of field thistle, 20~30 parts of oyster, 3~6 parts of pearl sand, 20~30 parts of pearl, 10~20 parts of honeysuckle.
Further, a kind of thrombolytic drug includes the component of following parts by weight：20~25 parts of ganoderma lucidum, 25~30 parts of field thistle,
25~30 parts of oyster, 4~6 parts of pearl sand, 25~30 parts of pearl, 15~20 parts of honeysuckle.
Preferably, a kind of thrombolytic drug includes the component of following parts by weight：22 parts of ganoderma lucidum, 26 parts of field thistle, oyster 26
Part, 5 parts of pearl sand, 26 parts of pearl, 16 parts of honeysuckle.
Preferably, the ganoderma lucidum is Wild ganoderma.
The major function of various medicinal materials used by inventive formulation is as follows：
Ganoderma lucidum, adjusts immune, improvement sleep, protecting liver and detoxication, and improvement blood circulation boosts metabolism, adjusts endocrine
System and cardio-cerebrovascular, strengthen the body resistance to consolidate the constitution, Yin Yang balancing, and help the five internal organs promote the vitality of body, promote longevity, are
The No.1 drug of preventing and treating diseases.
Field thistle, cooling blood and hemostasis, clearing heat for detumescence.
Oyster is best good medicine of replenishing the calcium, and confused and worried, insomnia of palpitating with fear has tranquilizing the mind effect, cures mainly palpitation with fear palpitation, insomnia
Dreaminess.
Cinnabar, blood-cleaning detoxifying, relieving convulsion relieving convulsion clear away heart-fire relieving convulsion.But it should not largely take.
Pearl, can hypertension and hyperlipemia, tissue space can be filled by repairing wound, and adhesion vascular tissue plays its anti-inflammatory, promote compared with
The effect of archaeocyte staple length.
Honeysuckle has chlorogenic acid, throat-clearing throat-moistening to exempt from thin adjusting, reducing blood lipid and anti-inflammatory effect.
The invention also discloses a kind of preparation methods of thrombolytic drug, include the following steps：
1) ganoderma lucidum, field thistle, oyster, honeysuckle are removed into impurity, and dries or dries；
2) each component is weighed according to the weight part ratio of component；
3) above-mentioned each component mixed in proportion, smashed, being ground up, sieved into herb powder, the grain size of herb powder is 110
~130 mesh, you can obtain thrombolytic drug of the present invention.
Thrombolytic drug of the present invention can decoct or take after mixing it with water, easy to operate, directly oral, without side-effects, be pure green environmental protection medicine
Object.
The present invention makes every effort to easy in preparation method, keeps drug fresh to greatest extent, and crude drug, drug is used to fry as possible
With, steam be all not so good as it is raw use, drug external application, life curative effect is best.The famous medicine scholar Ge Hong of the Eastern Jin Dynasty writes《Handbook of Prescriptions for Emergencies》
It is loaded with：" sweet wormwood one is held, and with two liters of stains of water, strand takes juice, takes it to the greatest extent ".Descendant has extracted qinghaosu on this basis, rescue
The life of countless malaria patients.It is taken so drug is only beaten powder by the present invention.
The present invention is obtained and is had the beneficial effect that using the above scheme：The selected suitable natural Chinese traditional medicines of thrombolytic drug of the present invention
Material and its proportioning, pharmaceutical formulation is unique, compatibility is reasonable, cooperates between each component, and every drug synergism has tonifying Qi
Beneficial blood is got through the effect of channels and collaterals, antitoxic heart-soothing and sedative, and curative effect is fast, short treating period, of low cost, convenient to take, Small side effects, controls
More rate is high, and treatment total effective rate is up to 96% or more.Drug of the present invention be suitable for thick coronary heart disease, blood, headache, dizziness, cerebral thrombus,
The illnesss such as brain tumor.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common
All other embodiment that technical staff is obtained without making creative work belongs to the model that the present invention protects
It encloses.
Embodiment 1, thrombolytic drug of the present invention include the component of following parts by weight：22 parts of ganoderma lucidum, 26 parts of field thistle, oyster 26
Part, 5 parts of pearl sand, 26 parts of pearl, 16 parts of honeysuckle.
The preparation method of thrombolytic drug of the present invention, includes the following steps：
1) ganoderma lucidum, field thistle, oyster, honeysuckle are removed into impurity, and dries or dries；
2) each component is weighed according to the weight part ratio of component；
3) above-mentioned each component mixed in proportion, smashed, being ground up, sieved into herb powder, the grain size of herb powder is 120
Mesh, you can obtain thrombolytic drug of the present invention.
Embodiment 2, thrombolytic drug of the present invention are 20 parts of ganoderma lucidum, 25 parts of field thistle, 25 parts of oyster, 4 parts of pearl sand, 25 parts of pearl, double
Spend 15 parts.
The preparation method of thrombolytic drug of the present invention, includes the following steps：
1) ganoderma lucidum, field thistle, oyster, honeysuckle are removed into impurity, and dries or dries；
2) each component is weighed according to the weight part ratio of component；
3) above-mentioned each component mixed in proportion, smashed, being ground up, sieved into herb powder, the grain size of herb powder is 115
Mesh, you can obtain thrombolytic drug of the present invention.
Embodiment 3, thrombolytic drug of the present invention are 25 parts of ganoderma lucidum, 30 parts of field thistle, 30 parts of oyster, 6 parts of pearl sand, 30 parts of pearl, double
Spend 20 parts.
The preparation method of thrombolytic drug of the present invention, includes the following steps：
1) ganoderma lucidum, field thistle, oyster, honeysuckle are removed into impurity, and dries or dries；
2) each component is weighed according to the weight part ratio of component；
3) above-mentioned each component mixed in proportion, smashed, being ground up, sieved into herb powder, the grain size of herb powder is 125
Mesh, you can obtain thrombolytic drug of the present invention.
With reference to the advantageous effect that clinical typical case further illustrates the present invention, but the invention is not limited in following
Clinical case.
Model case 1：
Chapter, female, 52 years old, cerebral thrombus 3 months, left limb bent and stretched not straight and numb, difficulty of walking, and takes medicine of the present invention
Object：Twice a day, once in the morning and once at night, above-mentioned symptom is clearly better after continuously taking one month, continues to take one and a half months hind leg
Body freedom of movement, is almost recovered.
Model case 2：
Mr. Wang, male, 49 years old, headache was dizzy, and extremity numbness is had a surplus for 2 years up and down in left side, and cerebral thrombus is diagnosed as after examination, in
It is to take drug of the present invention：Twice a day, once in the morning and once at night, above-mentioned symptom is extenuated after continuously taking one month, continues to take
With fully recovering after three months, call-on back by phone does not recur later.
Model case 3：
Slowly certain, man, 65 years old, slurred speech, facial paralysis, four limbs moving obstacle were had a surplus for 2 years, and cerebral infarction is diagnosed as after examination
Plug, then takes drug of the present invention：Twice a day, once in the morning and once at night, above-mentioned symptom is extenuated after continuously taking one and a half months,
It holds on and takes two and fully recover after half a month, do not recur so far.
Thrombolytic drug of the present invention can effectively clear up cardiovascular and cerebrovascular rubbish and reduce the sodium content in blood vessel, allow malicious secondary substance
All excrete.Conventional medicament is of no curative effect by expansion blood vessel.If patient's stomach is good during treatment, symptom compared with
Gently, the general 1-2 course for the treatment of can fully recover, and 3-4 course for the treatment of of patient of weight is almost recovered, and fullys recover from an illness and can not be relapsed after the healing, the present invention fills up
The blank of the medicinal streptokinase of the world world.
Example the above is only the implementation of the present invention is not intended to limit the scope of the invention, every to utilize this hair
Equivalent structure or equivalent flow shift made by bright description is applied directly or indirectly in other relevant technology necks
Domain is included within the scope of the present invention.
Claims (5)
1. a kind of thrombolytic drug, which is characterized in that include the component of following parts by weight：15~25 parts of ganoderma lucidum, 20~30 parts of field thistle,
20~30 parts of oyster, 3~6 parts of pearl sand, 20~30 parts of pearl, 10~20 parts of honeysuckle.
2. a kind of thrombolytic drug according to claim 1, which is characterized in that include the component of following parts by weight：Ganoderma lucidum 20
~25 parts, 25~30 parts of field thistle, 25~30 parts of oyster, 4~6 parts of pearl sand, 25~30 parts of pearl, 15~20 parts of honeysuckle.
3. a kind of thrombolytic drug according to claim 1, which is characterized in that include the component of following parts by weight：Ganoderma lucidum 22
Part, 26 parts of field thistle, 26 parts of oyster, 5 parts of pearl sand, 26 parts of pearl, 16 parts of honeysuckle.
4. a kind of thrombolytic drug according to claim 1, which is characterized in that include the component of following parts by weight：The spirit
Sesame is Wild ganoderma.
5. a kind of preparation method of thrombolytic drug, which is characterized in that include the following steps：
1) ganoderma lucidum, field thistle, oyster, honeysuckle are removed into impurity, and dries or dries；
2) each component is weighed according to the weight part ratio of component；
3) above-mentioned each component mixed in proportion, smashed, being ground up, sieved into herb powder, the grain size of herb powder is 110~
130 mesh, you can obtain thrombolytic drug of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810376119.7A CN108272850A (en) | 2018-04-25 | 2018-04-25 | A kind of thrombolytic drug and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810376119.7A CN108272850A (en) | 2018-04-25 | 2018-04-25 | A kind of thrombolytic drug and preparation method thereof |
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| Publication Number | Publication Date |
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| CN108272850A true CN108272850A (en) | 2018-07-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201810376119.7A Pending CN108272850A (en) | 2018-04-25 | 2018-04-25 | A kind of thrombolytic drug and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110755575A (en) * | 2019-11-11 | 2020-02-07 | 李利 | Medicine with stasis-breaking and thrombolysis effects and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1088823A (en) * | 1992-12-29 | 1994-07-06 | 淄博市淄川区第二制药厂 | The Chinese medicine preparation analgesia of treatment headache is peaceful |
| CN1325699A (en) * | 2000-05-31 | 2001-12-12 | 计英来 | Oral liquid 'Rongshuanling' |
| CN102961581A (en) * | 2012-12-06 | 2013-03-13 | 宁英琪 | Thrombolytic drug |
-
2018
- 2018-04-25 CN CN201810376119.7A patent/CN108272850A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1088823A (en) * | 1992-12-29 | 1994-07-06 | 淄博市淄川区第二制药厂 | The Chinese medicine preparation analgesia of treatment headache is peaceful |
| CN1325699A (en) * | 2000-05-31 | 2001-12-12 | 计英来 | Oral liquid 'Rongshuanling' |
| CN102961581A (en) * | 2012-12-06 | 2013-03-13 | 宁英琪 | Thrombolytic drug |
Non-Patent Citations (1)
| Title |
|---|
| 赫伟彦等: "疏血通合清开灵注射液治疗急性脑梗死临床观察", 《中国中医急症》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110755575A (en) * | 2019-11-11 | 2020-02-07 | 李利 | Medicine with stasis-breaking and thrombolysis effects and preparation method thereof |
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Application publication date: 20180713 |