CN108272744A

CN108272744A - A kind of capsule Essence and the method for manufacturing the capsule Essence

Info

Publication number: CN108272744A
Application number: CN201810383053.4A
Authority: CN
Inventors: 桑贤超
Original assignee: Beijing Herb Vierle Skin Care Products Co Ltd
Current assignee: Beijing Herb Vierle Skin Care Products Co Ltd
Priority date: 2018-04-26
Filing date: 2018-04-26
Publication date: 2018-07-13

Abstract

The invention discloses a kind of capsule Essences, including Essence and capsule, wherein capsule includes the liquid core being made of Essence and encapsulates the gel shell of liquid core completely, its advantage is that when capsule is not used, the active constituent in Essence will not occur to aoxidize and cause to fail because contacting with air；The invention also discloses a kind of methods of manufacture capsule Essence, Essence is injected dropper by this method using syringe, and then Essence is made to form drop in the exit of dropper, gelation reaction occurs in the container for be loaded with gel-based solution for drips, to form the gel shell of encapsulating liquid core completely, it is simple and efficient its advantage is that this method implements, the shell for the capsule produced is the shell of the carefully controlled structure with encapsulating liquid core.

Description

A kind of capsule Essence and the method for manufacturing the capsule Essence

Technical field

The present invention relates to a kind of capsule Essences and the method for manufacturing the capsule Essence, the Essence particularly to use Make skin care.

Background technology

Essence is that a kind of concentration is higher, powerful skin shield product, since it contains the active constituent of higher concentration, micro- Secondary element, collagen, serum etc., therefore with good anti-aging, crease-resistant, moisturizing, whitening, nti-freckle and other effects.

Essence is usually contained in ampulla, such as widely big well known MARTI DERM smoothnesses live flesh essence and MARTI DERM attain essence living of preserving youthful looks.When in use, it needs to break on the head of ampulla, then falls the Essence inside ampulla Go out or is sucked out.But an ampulla often can not be disposable complete, can cause in this way ampulla break rear active constituent therein with Air carries out the contact of a period of time, causes fractions of active ingredient to fail to which a degree of oxidation occur.In order to solve This problem, MARTI DERM smoothnesses work flesh essence and MARTI DERM, which attain in essence living of preserving youthful looks, is added to a certain amount of anti-corrosion Agent, to keep the activity of active material.

But for skin sensitive people, the addition of these preservatives be easy to cause the skin generation sensitivity of user, to Reduce skin care experience.

Invention content

The object of the present invention is to provide a kind of capsule Essences, its advantage is that the activity of the active constituent in capsule Essence It is kept well, while no added preservative in this capsule Essence, to reduce the risk of skin sensitivity.

The present invention above-mentioned technical purpose technical scheme is that：A kind of capsule Essence, including Essence for nourishing skin and the capsule for containing the Essence.

Wherein, active constituent, functional component and auxiliary element are contained in the Essence.Active constituent have it is relatively strong, Quick skin-care effect, functional component can play the nursing for further consolidating the active constituent to skin, and auxiliary element is then It is to play the role of coordinating the comprehensive of formula, sensory experience and usage experience and adjusting to formula is whole.

The capsule includes the liquid core being made of the Essence and encapsulates the gel shell of the liquid core completely. Without in use, Essence is encapsulated in gel shell, effectively its Essence is isolated with outside air for gel shell, to avoid Essence is in direct contact with air causes its fractions of active ingredient to aoxidize.When in use, gel shell is racked, is made therein Essence flows out, and the moment that Essence is extruded again, its active constituent maintained higher activity.

Further, since Essence by physical package in capsule, there is no need to preservative is added into Essence The activity for keeping active constituent, because without causing to cause user that skin sensitivity occurs because of the addition of preservative.

Preferred embodiment of the present invention is that the active constituent is selected from Ganodernaa lucidum extract, yeast tunning extract, Tujue Or mixtures thereof rose water, oat bran extract, dried tremella extract, Bacillus acidi lactici/rice fermentation product.

Further, weight percent of the active constituent in the Essence is between 20% and 90%.In this way It can ensure that the active constituent in this Essence has ideal concentration range, to be able to play the work(of active constituent Effect.If weight percent of the active constituent in the Essence is less than 20%, concentration of the active constituent in Essence is too low, Effect is not apparent enough；If weight percent of the active constituent in the Essence is higher than 20%, activity component concentration is excessively high, no Conducive to the absorption of skin.

Further, weight percent of the active constituent in the Essence is between 70% and 90%.This Sample one, it is ensured that the active constituent containing higher concentration in Essence, to make Essence that there is preferable skin effect.

Preferably, the functional component is selected from isoprene, niacinamide, hydroxy decyl ubiquinone, retinyl palmitate, fertility Phenol, polysorbate -20, palmitoyl oligopeptide, palmityl tetrapeptide -7, trehalose, tremella polysaccharides, alpha-arbutin, dipeptides diamino It is one or more in butyryl benzyl amide diacetin, 3-o- ethylascorbyls, can also be some of which or all at Divide the composition formed.

Wherein, hydroxy decyl ubiquinone has effects that anti-oxidant, removing free radical；Retinyl palmitate, which has, repairs face The effect of microgroove；Palmitoyl oligopeptide and palmityl tetrapeptide -7 have effects that stimulation collagen generation.Therefore general by hydroxy decyl The multifunctional antisenescence agent that quinone, retinyl palmitate, palmitoyl oligopeptide and palmityl tetrapeptide -7 form can be from three differences Dimension realize skin anti-aging maintenance, while according to chemical experiment research shows that（Such as refined series of Elizabethan）, hydroxyl Decyl ubiquinone and retinyl palmitate can play synergistic effect.

Further, weight percent of the functional component in the Essence is between 10% and 80%.In this way It can ensure that effect ingredient in this Essence has ideal concentration range.

Preferably, the auxiliary element includes one kind in carbomer, polysorbate -20, potassium hydroxide, polyacrylic acid Or it is a variety of.

Wherein, carbomer plays the role of thickener, and polysorbate -20 and polyacrylic acid play emulsifier Effect, potassium hydroxide play the role of acid-base modifier.

Further, weight percent of the auxiliary element in the Essence is no more than 5%.

Further, weight percent of the auxiliary element in the Essence is no more than 3%.

What needs to be explained here is that content of the auxiliary element in this Essence is relatively low, therefore the active constituent With the content of the functional component close to the relationship being mutually inversely proportional in this Essence, wherein active constituent and functional component Content can phase interworking it is suitable, to meet different demands.

The present invention also provides a kind of methods of manufacture capsule Essence, its advantage is that this method implements simple height Effect, the shell for the capsule produced are the shell of the carefully controlled structure with encapsulating liquid core.Wherein, the method includes Following steps：

A) Essence of the polyelectrolyte containing liquid is contained in syringe, the syringe is communicated with downward opening Dropper is equipped with container below the dropper, is loaded with gel-based solution in the container, containing can be in the gel-based solution The reactant that the polyelectrolyte reacts；

B) Essence is injected in the dropper using the syringe, drop is formed in the exit of the dropper；

C) drop makes the polyelectrolyte and the gel-based solution since gravity drippage is in gel-based solution It reacts, becomes gel state from liquid, and then form gel shell, the thickness of the gel shell is between the 0.5% of capsule diameter To between 1.5%；

D) the made capsule of recycling.

Preferably, weight percent of the polyelectrolyte in the Essence is between 0.5% and 2%.In this way may be used While to ensure that the thickness for eventually forming gel shell is enough well to wrap up Essence, capsule is made to be easy to rack when in use To make Essence therein flow out.

Further, the gel-based solution contains multivalent ion, and the polyelectrolyte is to react shape with multivalent ion At the polysaccharide of gel shell.

Wherein, had by the gel shell of the reacted formation of polysaccharide biocompatible, biodegradable and in majority of case Under nontoxic feature, after user racks capsule, and Essence therein is applied on skin, gel shell can be inhaled by skin It receives.

Further, the polysaccharide is fructose.It is reacted with multivalent ion because fructose can be passed through from the liquid of solution shape Become particularly sticky state afterwards, to form gel-like shell.

In conclusion the invention has the advantages that：

1, the activity of the active constituent in capsule Essence is kept well；

2, no added preservative, to reduce the risk of skin sensitivity；

3, method according to the present invention, which implements, is simple and efficient, and the shell for the capsule produced is with encapsulating liquid core The shell of carefully controlled structure.

Description of the drawings

Fig. 1 is capsule manufacturing method schematic diagram；

Fig. 2 is capsule structure schematic diagram；

In figure, 1, Essence；11, drop；2, capsule；21, liquid core；22, gel shell；3, syringe；4, dropper；5, container； 51, gel-based solution.

Specific implementation mode

In order to which the present invention is further explained and its advantage, following specific examples is provided, it should be understood that they are used only as Example is by no means limitative.In the next embodiment, unless otherwise specified, all parts and percentages are by weight Amount provides.

Embodiment 1

A kind of capsule Essence includes as depicted in figs. 1 and 2 Essence for nourishing skin and for containing Essence Capsule.Wherein, active constituent, functional component and auxiliary element are contained in Essence.Active constituent has relatively strong, quick shield Skin effect, functional component can play the nursing for further consolidating active constituent to skin, and auxiliary element is then to play cooperation The comprehensive, sensory experience and usage experience of formula and to the whole effect adjusted of formula；Capsule includes by Essence group At liquid core and completely encapsulating liquid core gel shell.

Without in use, Essence is encapsulated in gel shell, gel shell effectively by its Essence and outside air every From causing its fractions of active ingredient to aoxidize to avoid Essence and air from being in direct contact.When in use, gel shell is squeezed It is broken, so that Essence therein is flowed out, the moment that Essence is extruded again, its active constituent maintained higher activity.In addition, by In Essence by physical package in capsule, there is no need to add preservative into Essence to keep the work of active constituent Property, because without causing to cause user that skin sensitivity occurs because of the addition of preservative.

Preferred embodiment of the present invention is that active constituent can be selected from Ganodernaa lucidum extract, yeast tunning extract, Tujue Or mixtures thereof rose water, oat bran extract, dried tremella extract, Bacillus acidi lactici/rice fermentation product.

Further, weight percent of the active constituent in Essence can be between 20% and 90%.It in this way can be with Ensure that active constituent in this Essence has ideal concentration range, the effect of to be able to play active constituent. If weight percent of the active constituent in Essence is less than 20%, concentration of the active constituent in Essence is too low, and effect is inadequate Obviously；If weight percent of the active constituent in Essence is higher than 20%, activity component concentration is excessively high, is unfavorable for the suction of skin It receives.

Further, weight percent of the active constituent in Essence can be between 70% and 90%.Such one Come, it is ensured that the active constituent containing higher concentration in Essence, to make Essence that there is preferable skin effect.

Preferably, functional component can be selected from isoprene, niacinamide, hydroxy decyl ubiquinone, retinyl palmitate, fertility Phenol, polysorbate -20, palmitoyl oligopeptide, palmityl tetrapeptide -7, trehalose, tremella polysaccharides, alpha-arbutin, dipeptides diamino It is one or more in butyryl benzyl amide diacetin, 3-o- ethylascorbyls, can also be some of which or all at Divide the composition formed.

Further, weight percent of the functional component in Essence can be between 10% and 80%.It in this way can be with Ensure that effect ingredient in this Essence has ideal concentration range.

Preferably, auxiliary element may include one kind in carbomer, polysorbate -20, potassium hydroxide, polyacrylic acid Or it is a variety of.Wherein, carbomer plays the role of thickener, and polysorbate -20 and polyacrylic acid play emulsifier Effect, potassium hydroxide play the role of acid-base modifier.

Further, weight percent of the auxiliary element in Essence is not to be exceeded 5%.

Further, weight percent of the auxiliary element in Essence is not to be exceeded 3%.

What needs to be explained here is that content of the auxiliary element in this Essence is relatively low, therefore active constituent and the work( The content of ingredient is imitated in this Essence close to the relationship being mutually inversely proportional, the wherein content of active constituent and functional component can be with Phase interworking is suitable, to meet different demands.

The formula provided according to table 1 prepares Essence of the present invention.

Table 1

The processing method of Essence described in the present embodiment：

（1）Weighed water, Ganodernaa lucidum extract, yeast tunning extract, isoprene, potassium hydroxide and glycerine are mounted in 100 milliliters of beakers（Container A）In；

（2）By container A with low shear rate（200-300rpm）Continuous homogenization 3-5 minutes；

（3）By weighed water, trehalose, tremella polysaccharides, palmityl tripeptides -5, dipeptides diaminobutyryl benzyl amide oxalic acid Salt, Gotu Kola P.E, german chamomile flower extract, radix scutellariae root extract, Sodium Ascorbyl Phosphate, hydrolysis Sodium Hyaluronate, fourth Glycol, 1,2- hexylene glycols, glycerol caprylate, Sensiva SC50, appropriate serine, glycine, appropriate alanine, aspartic acid In right amount, appropriate valine, appropriate arginine, appropriate isoleucine, appropriate leucine, appropriate glutamic acid, appropriate proline, lactic acid Sodium, citric acid, ubiquinone, tocopherol acetate, palmitoyl oligopeptide, palmityl tetrapeptide -7, isoflavones and Sodium Hyaluronate dress In 50 milliliters of beakers（Container B）In；

（4）By container B with low shear rate（200-300rpm）Continuous homogenization 5-7 minutes；

（5）Weighed polysorbate -20, glycerol caprylate, carbomer are mounted in 20 milliliters of beakers（Container C）In；

（6）By container C with high-rate of shear（1000-1200rpm）It is heated to 75 °C under continuous homogenization and continues 5 minutes；

（7）Hereafter the hot mixt is made to be continuously stirred in low speed（500-700rmp）Under, it is cooled to room temperature；

（8）Substance in container B and container C is added in container A and is mixed；

（9）The mixture is set to be continuously stirred in low speed（500-700rmp）Under continue 5 minutes；

（10）Essence made of recycling.

A method of manufacture capsule Essence the described method comprises the following steps as depicted in figs. 1 and 2：

（1）Essence is contained in syringe, syringe is communicated with dropper, and dropper is opening down.It is placed with below dropper Container is loaded with gel-based solution in container.Wherein, liquid polyelectrolyte is contained in Essence, which can be with The gel shell that gelation reaction forms capsule occurs with gel-based solution.

（2）Essence is injected into dropper using syringe, and forms continuous drop at burette exit port；

（3）Drop is since gravity drips in gel-based solution, to keep the liquid in Essence poly- in gel-based solution Electrolyte and gel-based solution react to form gel shell, the thickness of the gel shell between capsule diameter 0.5% to 1.5% it Between；

（4）The made capsule of recycling.

Preferably, weight percent of the liquid polyelectrolyte in Essence is between 0.5% and 2%.

Further, gel-based solution contains multivalent ion, and polyelectrolyte is to react to form gel shell with multivalent ion Polysaccharide.Wherein, had by the gel shell of the reacted formation of polysaccharide biocompatible, biodegradable and in most cases Nontoxic feature, after user racks capsule, and Essence therein is applied on skin, gel shell can be by percutaneous absorption.

Further, which is fructose.Because fructose can be from the liquid of solution shape after being reacted with multivalent ion Become particularly sticky state, to form gel-like shell.

Embodiment 2

A kind of capsule Essence, difference from example 1 is that, the formula provided according to table 2 prepares essence of the present invention Magnificent liquid.

Table 2

The processing method of Essence described in the present embodiment：

（1）Weighed water, Tujue's rose water, potassium hydroxide and glycerine are mounted in 100 milliliters of beakers（Container A）In；

（3）Weighed water, trehalose, isoprene, tremella polysaccharides, alpha-arbutin, palmityl tripeptides -5,3-o- ethyls are resisted Bad hematic acid, 1,2- pentanediols, 1,2- hexylene glycols, glycerine, parahydroxyacet-ophenone, dipeptides diaminobutyryl benzyl amide oxalic acid It is salt, radix scutellariae root extract, german chamomile flower extract, Gotu Kola P.E, glycerol caprylate, butanediol, Sensiva SC50, transparent Matter acid sodium, palmitoyl oligopeptide, palmityl tetrapeptide -7, hydrolysis Sodium Hyaluronate, serine, glycine, alanine, aspartic acid, Valine, arginine, isoleucine, leucine, glutamic acid, proline, sodium lactate and citric acid are mounted in 50 milliliters of beakers（Container B）In；

（10）Essence made of recycling.

Embodiment 3

A kind of capsule Essence, difference from example 1 is that, the formula provided according to table 3 prepares essence of the present invention Magnificent liquid.

Table 3

The processing method of Essence described in the present embodiment：

（1）By weighed water, oat bran extract, dried tremella extract, Bacillus acidi lactici/rice fermentation product, potassium hydroxide It is mounted in 100 milliliters of beakers with glycerine（Container A）In；

（3）By weighed water, isoprene, niacinamide, hydroxy decyl ubiquinone, retinyl palmitate, tocopherol, polysorbate Ester -20, palmitoyl oligopeptide, palmityl tetrapeptide -7, glycerine, butanediol, serine, glycine, alanine, aspartic acid, figured silk fabrics ammonia Acid, arginine, isoleucine, leucine, glutamic acid, proline, sodium lactate, citric acid, Sensiva SC50, glycerine octanoic acid Ester, 1,2- hexylene glycols, radix scutellariae root extract, german chamomile flower extract, Gotu Kola P.E, dipeptides diaminobutyryl benzyl amide two Acetate, Sodium Hyaluronate, alpha-arbutin and stephania tetrandra extract are mounted in 50 milliliters of beakers（Container B）In；

（5）Weighed polyacrylic acid, polysorbate -20, glycerol caprylate, carbomer are mounted in 20 milliliters of beakers（Container C）In；

（10）Essence made of recycling.

This specific embodiment is only explanation of the invention, is not limitation of the present invention, people in the art Member can as needed make the present embodiment the modification of not creative contribution after reading this specification, but as long as at this It is all protected by Patent Law in the right of invention.

Claims

1. a kind of capsule Essence, including：

Essence (1) for nourishing skin, the Essence (1) contain active constituent, functional component and auxiliary element；With

Capsule (2) for containing the Essence (1), the capsule (2) include the liquid core being made of the Essence (1) (21) and completely the gel shell (22) of the liquid core (21) is encapsulated.

2. a kind of capsule Essence according to claim 1, it is characterized in that：The active constituent be selected from Ganodernaa lucidum extract, Yeast tunning extract, Tujue's rose water, oat bran extract, dried tremella extract, Bacillus acidi lactici/rice fermentation production Or mixtures thereof object.

3. a kind of capsule Essence according to claim 2, it is characterized in that：The active constituent is in the Essence (1) In weight percent between 20% and 90%.

4. a kind of capsule Essence according to claim 3, it is characterized in that：The active constituent is in the Essence (1) In weight percent between 70% and 90%.

5. a kind of capsule Essence according to claim 1, it is characterized in that：The functional component includes isoprene, cigarette Amide, hydroxy decyl ubiquinone, retinyl palmitate, tocopherol, polysorbate -20, palmitoyl oligopeptide, palmityl tetrapeptide -7, Trehalose, tremella polysaccharides, alpha-arbutin, dipeptides diaminobutyryl benzyl amide diacetin and 3-o- ethylascorbyls.

6. a kind of capsule Essence according to claim 5, it is characterized in that：The functional component is in the Essence (1) In weight percent between 10% and 80%.

7. a kind of capsule Essence according to claim 1, it is characterized in that：The auxiliary element includes carbomer, poly- mountain Pears alcohol ester -20, potassium hydroxide and polyacrylic acid.

8. a kind of capsule Essence according to claim 7, it is characterized in that：The auxiliary element is in the Essence (1) In weight percent be no more than 5%.

9. a kind of capsule Essence according to claim 8, it is characterized in that：The auxiliary element is in the Essence (1) In weight percent be no more than 3%.

10. a kind of method of manufacture capsule Essence, includes the following steps：

A) Essence (1) of the polyelectrolyte containing liquid is contained in syringe (3), the syringe (3) is communicated with out The dropper (4) of mouth down, dropper (4) lower section are equipped with container (5), gel-based solution (51) are loaded in the container (5), Contain the reactant that can be reacted with the polyelectrolyte in the gel-based solution (51)；

B) Essence (1) is injected in the dropper (4) using the syringe (3), the outlet in the dropper (4) Place forms drop (11)；

C) drop (11) makes the polyelectrolyte be coagulated with described since gravity drippage is in gel-based solution (51) Gelled solutions (51) react, and become gel state from liquid, and then form gel shell (22), the thickness of the gel shell (22) Degree is between the 0.5% to 1.5% of capsule (2) diameter；

D) the made capsule (2) of recycling.

11. a kind of method of manufacture capsule Essence according to claim 10, it is characterized in that：The polyelectrolyte is in institute The weight percent in Essence (1) is stated between 0.5% and 2%.

12. a kind of method of manufacture capsule Essence according to claim 11, it is characterized in that：The gel-based solution (51) contain multivalent ion, the polyelectrolyte is that the polysaccharide to form gel shell (22) can be reacted with multivalent ion.

13. a kind of method of manufacture capsule Essence according to claim 12, it is characterized in that：The polysaccharide is fructose.