CN108241068A - 一种自动化微体积移液与分配装置及其使用方法 - Google Patents
一种自动化微体积移液与分配装置及其使用方法 Download PDFInfo
- Publication number
- CN108241068A CN108241068A CN201711394895.1A CN201711394895A CN108241068A CN 108241068 A CN108241068 A CN 108241068A CN 201711394895 A CN201711394895 A CN 201711394895A CN 108241068 A CN108241068 A CN 108241068A
- Authority
- CN
- China
- Prior art keywords
- suction nozzle
- oil
- liquid
- accurate
- volume
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 86
- 238000000034 method Methods 0.000 title claims abstract description 22
- 238000013519 translation Methods 0.000 claims abstract description 37
- 239000012530 fluid Substances 0.000 claims abstract description 22
- 238000002347 injection Methods 0.000 claims abstract description 12
- 239000007924 injection Substances 0.000 claims abstract description 12
- 238000005213 imbibition Methods 0.000 claims abstract description 7
- 238000011068 loading method Methods 0.000 claims abstract description 7
- 239000003921 oil Substances 0.000 claims description 55
- 239000000523 sample Substances 0.000 claims description 31
- 230000008859 change Effects 0.000 claims description 14
- 239000012488 sample solution Substances 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 238000003860 storage Methods 0.000 claims description 7
- 239000002480 mineral oil Substances 0.000 claims description 6
- 235000010446 mineral oil Nutrition 0.000 claims description 6
- 238000009826 distribution Methods 0.000 claims description 5
- 150000001335 aliphatic alkanes Chemical class 0.000 claims description 4
- 150000002148 esters Chemical class 0.000 claims description 4
- 229920002545 silicone oil Polymers 0.000 claims description 4
- 239000002699 waste material Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 abstract description 5
- 238000012216 screening Methods 0.000 abstract description 5
- 239000012071 phase Substances 0.000 description 12
- 230000008569 process Effects 0.000 description 9
- 238000010586 diagram Methods 0.000 description 7
- 238000005516 engineering process Methods 0.000 description 6
- 235000015927 pasta Nutrition 0.000 description 4
- 238000009529 body temperature measurement Methods 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000003044 adaptive effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000007877 drug screening Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000000520 microinjection Methods 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
Abstract
Description
Claims (14)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202211243214.2A CN116298353A (zh) | 2016-12-27 | 2017-12-21 | 一种用于微体积液体移液操作的装置 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2016112279132 | 2016-12-27 | ||
CN201611227913 | 2016-12-27 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202211243214.2A Division CN116298353A (zh) | 2016-12-27 | 2017-12-21 | 一种用于微体积液体移液操作的装置 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108241068A true CN108241068A (zh) | 2018-07-03 |
Family
ID=62701103
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202211243214.2A Pending CN116298353A (zh) | 2016-12-27 | 2017-12-21 | 一种用于微体积液体移液操作的装置 |
CN201711394895.1A Pending CN108241068A (zh) | 2016-12-27 | 2017-12-21 | 一种自动化微体积移液与分配装置及其使用方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202211243214.2A Pending CN116298353A (zh) | 2016-12-27 | 2017-12-21 | 一种用于微体积液体移液操作的装置 |
Country Status (1)
Country | Link |
---|---|
CN (2) | CN116298353A (zh) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108786179A (zh) * | 2018-08-31 | 2018-11-13 | 中触媒新材料股份有限公司 | 一种柱层析分离全自动部份收集装置及方法 |
WO2021037218A1 (zh) * | 2019-08-30 | 2021-03-04 | 北京达微生物科技有限公司 | 一种制备微液滴的加样针以及微液滴的制备方法 |
CN112457972A (zh) * | 2020-11-30 | 2021-03-09 | 倍仪昇智能科技(苏州)有限公司 | Pcr检测病毒前处理装置及方法 |
CN115106143A (zh) * | 2022-06-29 | 2022-09-27 | 合肥瀚海星点生物科技有限公司 | 一种高精度电动微量液体移液器 |
CN115722280A (zh) * | 2021-08-26 | 2023-03-03 | 北京达微生物科技有限公司 | 一种用于微液滴制备的控制装置及制备微液滴的方法 |
CN115770631A (zh) * | 2022-12-07 | 2023-03-10 | 深圳市恒永达科技股份有限公司 | 一种环境自适应空气式移液泵及其控制方法 |
Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1956786A (zh) * | 2003-11-27 | 2007-05-02 | 吉尔松有限合伙公司 | 在液体取样移液管中精确量取液体的系统和方法 |
CN101332439A (zh) * | 2007-06-26 | 2008-12-31 | 上海裕隆生物科技有限公司 | 一种自动移液工作站 |
CN102016540A (zh) * | 2008-04-11 | 2011-04-13 | 梅索斯卡莱科技公司 | 分析装置、方法和试剂 |
CN102954954A (zh) * | 2012-09-19 | 2013-03-06 | 东南大学 | 基于磁分离的多样本多位点高通量核酸分析系统 |
CN102961806A (zh) * | 2012-12-10 | 2013-03-13 | 同济大学 | 医用反馈式柱状压电自动微量注射器 |
CN103008037A (zh) * | 2012-12-31 | 2013-04-03 | 浙江大学 | 一种具有皮升级精度的自动化微液滴阵列筛选系统的使用方法 |
CN103008040A (zh) * | 2012-09-05 | 2013-04-03 | 罗耿荣 | 自动修正精度的电动移液器及其精度修正方法 |
CN103282781A (zh) * | 2010-11-23 | 2013-09-04 | 安德鲁联合有限公司 | 用于移液管的可编程操纵的设备和方法 |
CN104089804A (zh) * | 2014-07-02 | 2014-10-08 | 上海乐辰生物科技有限公司 | 生物样品处理系统 |
CN104777161A (zh) * | 2015-03-27 | 2015-07-15 | 北京大学 | 一种固定化微胶囊检测阵列及其加工方法和应用 |
CN104849111A (zh) * | 2015-04-14 | 2015-08-19 | 浙江大学 | 基于顺序注射和微流控技术的梯度微液滴阵列的形成方法 |
CN105510566A (zh) * | 2015-11-30 | 2016-04-20 | 武汉理工大学 | 一种环氧树脂固化收缩体积实时监测方法 |
CN105821482A (zh) * | 2016-04-29 | 2016-08-03 | 李星军 | 一种生化微反应体系、高通量测序的建库仪及应用 |
CN208721693U (zh) * | 2016-12-27 | 2019-04-09 | 中国科学院微生物研究所 | 一种自动化微体积移液与分配装置 |
-
2017
- 2017-12-21 CN CN202211243214.2A patent/CN116298353A/zh active Pending
- 2017-12-21 CN CN201711394895.1A patent/CN108241068A/zh active Pending
Patent Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1956786A (zh) * | 2003-11-27 | 2007-05-02 | 吉尔松有限合伙公司 | 在液体取样移液管中精确量取液体的系统和方法 |
CN101332439A (zh) * | 2007-06-26 | 2008-12-31 | 上海裕隆生物科技有限公司 | 一种自动移液工作站 |
CN102016540A (zh) * | 2008-04-11 | 2011-04-13 | 梅索斯卡莱科技公司 | 分析装置、方法和试剂 |
CN103282781A (zh) * | 2010-11-23 | 2013-09-04 | 安德鲁联合有限公司 | 用于移液管的可编程操纵的设备和方法 |
CN103008040A (zh) * | 2012-09-05 | 2013-04-03 | 罗耿荣 | 自动修正精度的电动移液器及其精度修正方法 |
CN102954954A (zh) * | 2012-09-19 | 2013-03-06 | 东南大学 | 基于磁分离的多样本多位点高通量核酸分析系统 |
CN102961806A (zh) * | 2012-12-10 | 2013-03-13 | 同济大学 | 医用反馈式柱状压电自动微量注射器 |
CN103008037A (zh) * | 2012-12-31 | 2013-04-03 | 浙江大学 | 一种具有皮升级精度的自动化微液滴阵列筛选系统的使用方法 |
CN104089804A (zh) * | 2014-07-02 | 2014-10-08 | 上海乐辰生物科技有限公司 | 生物样品处理系统 |
CN104777161A (zh) * | 2015-03-27 | 2015-07-15 | 北京大学 | 一种固定化微胶囊检测阵列及其加工方法和应用 |
CN104849111A (zh) * | 2015-04-14 | 2015-08-19 | 浙江大学 | 基于顺序注射和微流控技术的梯度微液滴阵列的形成方法 |
CN105510566A (zh) * | 2015-11-30 | 2016-04-20 | 武汉理工大学 | 一种环氧树脂固化收缩体积实时监测方法 |
CN105821482A (zh) * | 2016-04-29 | 2016-08-03 | 李星军 | 一种生化微反应体系、高通量测序的建库仪及应用 |
CN208721693U (zh) * | 2016-12-27 | 2019-04-09 | 中国科学院微生物研究所 | 一种自动化微体积移液与分配装置 |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108786179A (zh) * | 2018-08-31 | 2018-11-13 | 中触媒新材料股份有限公司 | 一种柱层析分离全自动部份收集装置及方法 |
WO2021037218A1 (zh) * | 2019-08-30 | 2021-03-04 | 北京达微生物科技有限公司 | 一种制备微液滴的加样针以及微液滴的制备方法 |
CN112457972A (zh) * | 2020-11-30 | 2021-03-09 | 倍仪昇智能科技(苏州)有限公司 | Pcr检测病毒前处理装置及方法 |
CN115722280A (zh) * | 2021-08-26 | 2023-03-03 | 北京达微生物科技有限公司 | 一种用于微液滴制备的控制装置及制备微液滴的方法 |
CN115106143A (zh) * | 2022-06-29 | 2022-09-27 | 合肥瀚海星点生物科技有限公司 | 一种高精度电动微量液体移液器 |
CN115770631A (zh) * | 2022-12-07 | 2023-03-10 | 深圳市恒永达科技股份有限公司 | 一种环境自适应空气式移液泵及其控制方法 |
CN115770631B (zh) * | 2022-12-07 | 2023-08-15 | 深圳市恒永达科技股份有限公司 | 一种环境自适应空气式移液泵及其控制方法 |
Also Published As
Publication number | Publication date |
---|---|
CN116298353A (zh) | 2023-06-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN108241068A (zh) | 一种自动化微体积移液与分配装置及其使用方法 | |
Ainla et al. | A multifunctional pipette | |
DK167999B1 (da) | Engangskapillarpipetteindretning med forud fastlagt rumfang og fremgangsmaade til udtagning af en vaeskeproeve til proevning | |
EP1364710B1 (en) | Self-aliquoting sample storage plate | |
US10119112B2 (en) | Multi-reactor unit for dynamic cell culture | |
US20100135853A1 (en) | Automatic isothermal titration microcalorimeter apparatus and method of use | |
EP2050498A1 (en) | Fluid handling device for analysis of fluid samples | |
WO2015006751A1 (en) | Systems and methods for cell culture device interconnection and fluidic device interconnection | |
JPH01257268A (ja) | 液体サンプルの稀釈及び混合のための装置及び方法 | |
CN110787851B (zh) | 基于压力驱动的多通道液滴定量量取装置与量取方法 | |
WO2019185927A1 (en) | Microfluidic chip | |
EP0747689A2 (en) | Liquid aspiration from a sealed container | |
WO2015136991A1 (ja) | 分注装置及び分注方法 | |
WO2017030455A1 (en) | Microfluidic chip with pressure and flow control system | |
CN110369011A (zh) | 基于液压驱动的微量液体转移装置、控制设备及控制方法 | |
CN202033242U (zh) | 用于原子光谱分析的全自动液体处理工作站 | |
CN208721693U (zh) | 一种自动化微体积移液与分配装置 | |
CN208847750U (zh) | 基于超疏水材料的微量注射器水珠精准剥离、投放装置 | |
JP6556220B2 (ja) | 三相流体の取扱い | |
JPWO2008096570A1 (ja) | マイクロチップ、およびマイクロチップ検査システム | |
US20050197538A1 (en) | Reagent and sample introduction plunger device for a syringe | |
US8420030B2 (en) | Well plate for holding a sample during analysis and a method for preparing a sample for analysis | |
Columbus et al. | The integrated blood-collection system as a vehicle into complete clinical laboratory automation | |
CN105910878A (zh) | 一种用于微流体通道中气体去除的装置 | |
CN201010507Y (zh) | 高精度微量加液器 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20200527 Address after: 100176 No. 2 middle Sheng Road, Daxing District economic and Technological Development Zone, Beijing Applicant after: HOLLYSYS AUTOMATION TECHNOLOGIES Ltd. Address before: 100101 No. 1, West Beichen Road, Beijing, Chaoyang District, 3 Applicant before: INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20200814 Address after: B106, 1 / F, No.5 Kaifa Road, Haidian District, Beijing 100085 Applicant after: Beijing Da Microbiology Technology Co.,Ltd. Address before: 100176 No. 2 middle Sheng Road, Daxing District economic and Technological Development Zone, Beijing Applicant before: HOLLYSYS AUTOMATION TECHNOLOGIES Ltd. |
|
CB02 | Change of applicant information |
Address after: Room 101, 1F, Room 201, 2F, Building 16, Yard 79, Shuangying West Road, Science Park, Changping District, Beijing 100085 Applicant after: Beijing Da Microbiology Technology Co.,Ltd. Address before: 100085 B106, 1st floor, No.5 Kaifa Road, Haidian District, Beijing Applicant before: Beijing Da Microbiology Technology Co.,Ltd. |
|
CB02 | Change of applicant information | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20230926 Address after: 611731 building 4, No.8, Anhe 2nd Road, hi tech Zone, Chengdu, Sichuan Province Applicant after: MACCURA MEDICAL ELECTRONICS Co.,Ltd. Address before: Room 101, 1F, Room 201, 2F, Building 16, Yard 79, Shuangying West Road, Science Park, Changping District, Beijing 100085 Applicant before: Beijing Da Microbiology Technology Co.,Ltd. |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20231213 Address after: No. 16 Baichuan Road, High tech Zone, Chengdu City, Sichuan Province, 610097 Applicant after: MACCURA BIOTECHNOLOGY Co.,Ltd. Address before: 611731 building 4, No.8, Anhe 2nd Road, hi tech Zone, Chengdu, Sichuan Province Applicant before: MACCURA MEDICAL ELECTRONICS Co.,Ltd. |
|
TA01 | Transfer of patent application right |