CN108210781A

CN108210781A - It is a kind of to promote hematoblastic compound selenium Chinese herbal and crude drugs preparations

Info

Publication number: CN108210781A
Application number: CN201810204033.6A
Authority: CN
Inventors: 程先平
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-03-13
Filing date: 2018-03-13
Publication date: 2018-06-29

Abstract

A kind of to promote hematoblastic compound selenium Chinese herbal and crude drugs preparations, the present invention relates to pharmaceutical technology fields；It is made of following weight item：12 15g of the bletilla striata, 12 15 g of rhizoma imperatae, 12 15g of charred NODUS NELUMBINIS RHIZOMATIS, 69 g of Caulis Spatholobi, 180 200 μ g of Organic Selenium.Hematoblastic quantity can significantly be increased, promote hematoblastic function, bone marrow suppression, immunosupress and other side effects etc. caused by the use simultaneously of tumor patient chemicotherapy can mitigate chemicotherapy.

Description

It is a kind of to promote hematoblastic compound selenium Chinese herbal and crude drugs preparations

Technical field

The present invention relates to pharmaceutical technology fields, and in particular to a kind of to promote hematoblastic compound selenium Chinese herbal and crude drugs preparations.

Background technology

Chinese patent drug is the rarity of world traditional medicine, the specific manifestation of Chinese achievement civilized for thousands of years, genuine Chinese medicine Huge contribution is made that with health of the experience prescription for China and the people of the world, cannot be solved in certain fields, particularly doctor trained in Western medicine Certainly or curative effect it is not good enough medical treatment and big health field have more characteristic, clinically, caused by tumour Radiotherapy chemotherapy or other a variety of causes Platelet counts are reduced and/or insufficiency is common, though and there are TPO and cell factor IL-11 class medicinal applications, a clinical efficacy Meet clinical demand with still difficulty in terms of side effect, because blood source and curative effect problem status significantly decline, blood platelet subtracts for component blood transfusion Few is still clinical problem, and without effective prevention decrease of platelet good plan.This prescription commonly uses Empirical formula, clinical verification to be clinical Using platelet counts can be obviously improved, and can enhance platelet function, the incidence of bleeding during blood platelet reduces is reduced, especially It can obviously reduce the amplitude and thrombopenia of blood platelet decline importantly, in the application of the tumor patient chemicotherapy same period Incidence, there is apparent prevention to be worth.

Human body is made of macroelement and more than ten kind trace elements, micro- but function pole atomic in people's in-vivo content Its is important, is human essential elements, can only be orally ingested, wherein, selenium is a kind of most important micro elements needed by human, research Show：A variety of chronic diseases that it lacks with Keshan disease and including tumour are related, have in the prevention of tumour chronic diseases higher Application value.Selenium application in tumor patient can mitigate the side effect of Radiotherapy chemotherapy, including the weight such as digestive tract reaction, conscience kidney Prevention of organ protection and bone marrow suppression etc. is wanted, while selenium can also clear up human internal environment, body damages caused by promoting Radiotherapy chemotherapy Immunity of organisms decline etc. caused by the reparation of wound, protection and promotion chemicotherapy.

Chinese patent medicine preparation is made in selenium, bone marrow suppression caused by chemicotherapy can be mitigated, immunosupress and other side effects Deng.

Invention content

In view of the defects and deficiencies of the prior art, the present invention intends to provide a kind of ingredient is simple, reasonable design Hematoblastic compound selenium Chinese herbal and crude drugs preparations are promoted, can significantly increase hematoblastic quantity, hematoblastic function be promoted, in tumour Bone marrow suppression, immunosupress and other side effects etc. caused by the use simultaneously of patient's chemicotherapy can mitigate chemicotherapy.

To achieve the above object, the technical solution adopted by the present invention is：It is made of following parts by weight ingredient：Bletilla striata 12- 15g, rhizoma imperatae 12-15g, charred NODUS NELUMBINIS RHIZOMATIS 12-15g, Caulis Spatholobi 6-9g, Organic Selenium 180-200 μ g.

Further, the hematoblastic compound selenium Chinese herbal and crude drugs preparations of the promotion, it is made of following parts by weight ingredient： Bletilla striata 14-15g, rhizoma imperatae 14-15g, charred NODUS NELUMBINIS RHIZOMATIS 14-15g, Caulis Spatholobi 8-9g, Organic Selenium 190-200 μ g.

Further, the hematoblastic compound selenium Chinese herbal and crude drugs preparations of the promotion, it is made of following parts by weight ingredient： Bletilla striata 12-13g, rhizoma imperatae 12-13g, charred NODUS NELUMBINIS RHIZOMATIS 12-13g, Caulis Spatholobi 6-7g, Organic Selenium 180-190 μ g.

Further, contain one kind or more in addition to selenium in the hematoblastic compound selenium Chinese herbal and crude drugs preparations of promotion Kind trace element.

The procedure of processing of the present invention is as follows：

1st, the bletilla striata, rhizoma imperatae, charred NODUS NELUMBINIS RHIZOMATIS and the Caulis Spatholobi of parts by weight, manually fried or use extraction stoste are chosen；

2nd, stoste is filtered successively, sterilized；

3rd, the Organic Selenium that microbial fermentation is crossed is added into the stoste after filtering and sterilizing, the reaction was continued at a certain temperature；

4th, will react the liquid that obtains later carry out it is filling, it is filling in Organic Selenium amount be 180-200 μ g/ agent, you can.

Further, it is filtered in the step 2 using filtering equipment.

Further, it is sterilized in the step 2 using high temperature sterilization, sterilising temp is Celsius for 1000-1500 Degree, sterilization time are 5-8 hours.

Further, fermentation temperature is 50-120 degrees Celsius in the step 3, and fermentation time is 14 days.

The present invention instructions of taking be:According to above-mentioned dosage one dose per day, take twice.

The present invention has the beneficial effect that：

1st, the effect of platelet counts can be obviously improved, being taken while chemicotherapy starts can be declined with substantially reduced blood platelet Degree and the duration, ensure chemicotherapy complete on schedule；

2nd, there are certain leucocyte promotion and immune function castering action, also certain prevention is taken while chemicotherapy starts Leucocyte declines and immanoprotection action；

3rd, start, i.e. by one dose per day, to take twice in tumor patient chemicotherapy, also there is certain interior environment liquidation value, energy Conscience injury of kidney caused by protecting chemicotherapy promotes mucous membrane and other injury repairs etc. caused by chemicotherapy.

Specific embodiment

Present embodiment（Embodiment one）The technical solution adopted is that：It is made of following parts by weight ingredient：The bletilla striata 13g, rhizoma imperatae 13g, charred NODUS NELUMBINIS RHIZOMATIS 13g, Caulis Spatholobi 7g, 190 μ g of Organic Selenium.

The procedure of processing of present embodiment is as follows：

1st, bletilla striata 13g, rhizoma imperatae 13g, charred NODUS NELUMBINIS RHIZOMATIS 13g, Caulis Spatholobi 7g are chosen, it is manually fried to obtain stoste；

2nd, stoste using filtering equipment is filtered, is sterilized using high temperature sterilization, sterilising temp is 1000 degrees Celsius, sterilizing Time is 8 hours；

3rd, the 190 μ g of Organic Selenium that microbial fermentation is crossed are added into the stoste after filtering and sterilizing, are continued at a certain temperature anti- Should, fermentation temperature is 110 degrees Celsius, and fermentation time is 14 days；

4th, the liquid that obtains later will be reacted to concentrate, paste is made, then the paste carried out it is filling, it is filling in it is organic Selenium amount is 190 μ g/agent, you can.

The instructions of taking of present embodiment is:According to above-mentioned dosage one dose per day, take twice.

Present embodiment has the beneficial effect that：The hematoblastic compound selenium of a kind of promotion that present embodiment provides Chinese herbal and crude drugs preparations can significantly increase hematoblastic quantity, promote hematoblastic function, can in the use simultaneously of tumor patient chemicotherapy Bone marrow suppression caused by mitigate chemicotherapy and immunosupress and other side effects etc..

Embodiment two：

The hematoblastic compound selenium Chinese herbal and crude drugs preparations of promotion described in the present embodiment, it is made of following parts by weight ingredient：In vain Splendid achnatherum 15g, rhizoma imperatae 15g, charred NODUS NELUMBINIS RHIZOMATIS 15g, Caulis Spatholobi 9g, 200 μ g of Organic Selenium.

The procedure of processing of the present embodiment is as follows：

1st, bletilla striata 15g, rhizoma imperatae 15g, charred NODUS NELUMBINIS RHIZOMATIS 15g, Caulis Spatholobi 9g are chosen, stoste is obtained through extraction；

2nd, stoste using filtering equipment is filtered, is sterilized using high temperature sterilization, sterilising temp is 1000 degrees Celsius, sterilizing Time is 7 hours；

3rd, the 200 μ g of Organic Selenium that microbial fermentation is crossed are added into the stoste after filtering and sterilizing, are continued at a certain temperature anti- Should, fermentation temperature is 100 degrees Celsius, and fermentation time is 14 days；

4th, the liquid evaporation concentration obtained later will be reacted, be made solid, then the solid carried out it is filling, it is filling in Organic Selenium It measures as 200 μ g/agent, you can.

The instructions of taking of the present embodiment is:According to above-mentioned dosage one dose per day, take twice.

Embodiment three：

The hematoblastic compound selenium Chinese herbal and crude drugs preparations of promotion described in the present embodiment, it is made of following parts by weight ingredient：In vain Splendid achnatherum 12g, rhizoma imperatae 12g, charred NODUS NELUMBINIS RHIZOMATIS 12g, Caulis Spatholobi 6g, 185 μ g of Organic Selenium.

The procedure of processing of the present embodiment is as follows：

1st, bletilla striata 12g, rhizoma imperatae 12g, charred NODUS NELUMBINIS RHIZOMATIS 12g, Caulis Spatholobi 6g are chosen, it is manually fried to obtain stoste；

2nd, stoste using filtering equipment is filtered, is sterilized using high temperature sterilization, sterilising temp is 1200 degrees Celsius, sterilizing Time is 7 hours；

3rd, the 185 μ g of Organic Selenium that microbial fermentation is crossed are added into the stoste after filtering and sterilizing, are continued at a certain temperature anti- Should, fermentation temperature is 50 degrees Celsius, and fermentation time is 14 days；

4th, will react the liquid that obtains later carry out it is filling, it is filling in Organic Selenium amount be 185 μ g/agent, you can.

The above is merely illustrative of the technical solution of the present invention and unrestricted, and those of ordinary skill in the art are to this hair The other modifications or equivalent replacement that bright technical solution is made, without departing from the spirit and scope of technical solution of the present invention, It is intended to be within the scope of the claims of the invention.

Claims

1. a kind of promote hematoblastic compound selenium Chinese herbal and crude drugs preparations, it is characterised in that：It is made of following parts by weight ingredient：In vain Splendid achnatherum 12-15g, rhizoma imperatae 12-15g, charred NODUS NELUMBINIS RHIZOMATIS 12-15g, Caulis Spatholobi 6-9g, Organic Selenium 180-200 μ g.

2. a kind of hematoblastic compound selenium Chinese herbal and crude drugs preparations of promotion according to claim 1, it is characterised in that：Described Hematoblastic compound selenium Chinese herbal and crude drugs preparations are promoted, it is made of following parts by weight ingredient：Bletilla striata 14-15g, rhizoma imperatae 14- 15g, charred NODUS NELUMBINIS RHIZOMATIS 14-15g, Caulis Spatholobi 8-9g, Organic Selenium 190-200 μ g.

3. a kind of hematoblastic compound selenium Chinese herbal and crude drugs preparations of promotion according to claim 1, it is characterised in that：Described Hematoblastic compound selenium Chinese herbal and crude drugs preparations are promoted, it is made of following parts by weight ingredient：Bletilla striata 12-13g, rhizoma imperatae 12- 13g, charred NODUS NELUMBINIS RHIZOMATIS 12-13g, Caulis Spatholobi 6-7g, Organic Selenium 180-190 μ g.

4. a kind of hematoblastic compound selenium Chinese herbal and crude drugs preparations of promotion according to claim 1, it is characterised in that：Described It is promoted in hematoblastic compound selenium Chinese herbal and crude drugs preparations containing one or more trace elements in addition to selenium.

5. a kind of promote hematoblastic compound selenium Chinese herbal and crude drugs preparations, it is characterised in that：Its procedure of processing is as follows：

(1), the bletilla striata, rhizoma imperatae, charred NODUS NELUMBINIS RHIZOMATIS and the Caulis Spatholobi of parts by weight, manually fried or use extraction stoste are chosen；

(2), stoste is filtered successively, sterilized；

(3), the Organic Selenium that microbial fermentation is crossed is added into the stoste after filtering and sterilizing, the reaction was continued at a certain temperature；

(4), will react the liquid that obtains later carry out it is filling, it is filling in Organic Selenium amount be 180-200 μ g/ agent, you can.

6. a kind of hematoblastic compound selenium Chinese herbal and crude drugs preparations of promotion according to claim 1, it is characterised in that：Described It is filtered in step (2) using filtering equipment.

7. a kind of hematoblastic compound selenium Chinese herbal and crude drugs preparations of promotion according to claim 1, it is characterised in that：Described It is sterilized in step (2) using high temperature sterilization, sterilising temp is 1000-1500 degrees Celsius, and sterilization time is 5-8 hours.

8. a kind of hematoblastic compound selenium Chinese herbal and crude drugs preparations of promotion according to claim 1, it is characterised in that：Described Fermentation temperature is 50-120 degrees Celsius in step (3), and fermentation time is 14 days.