CN108208828A - A kind of composition of the Cordyceps militaris containing maca and preparation method thereof - Google Patents
A kind of composition of the Cordyceps militaris containing maca and preparation method thereof Download PDFInfo
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- CN108208828A CN108208828A CN201711391847.7A CN201711391847A CN108208828A CN 108208828 A CN108208828 A CN 108208828A CN 201711391847 A CN201711391847 A CN 201711391847A CN 108208828 A CN108208828 A CN 108208828A
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides a kind of composition of the Cordyceps militaris containing maca and preparation method thereof.By weight, the composition of the Cordyceps militaris containing maca is prepared by the raw material for including following component：5 20 parts of 10 30 parts of pueraria root powder, 5 25 parts of Cordyceps militaris and donkey-hide gelatin.The effect of present invention combines the pueraria root powder of specified weight part, Cordyceps militaris and donkey-hide gelatin under the guidance of theory of traditional Chinese medical science, and the composition containing above-mentioned three components can give full play to various composition.Compared to single component, composition of the invention remittance enrich blood, invigorating the spleen, eliminating evil, conditioning in a side, collaboration plays a role.
Description
Technical field
The present invention relates to composite preparation field, more particularly, to the composition and its system of a kind of Cordyceps militaris containing maca
Preparation Method.
Background technology
Cordyceps militaris has bidirectional modulation immune system, the effectiveness for controling other treasures.Briefly, bidirectional modulation is exactly to allow people
Normal condition is transferred in the too low physiological performance value of body, and can be excessively high readjustment to normal level.Cordyceps militaris is exactly to count not
More to take a tonic or nourishing food to build up one's health physically weak but also qi and blood is inhibited to cross one of medicinal material of Sheng, Cordyceps militaris is also to a variety of solid malignants, streptococcus
Pathogens is waited to have very strong inhibiting effect, harmful free radical can be eliminated, are slowed down aging.
Maca grows the Andes of 4000 meters or so of height above sea level in the middle part of Peru in South America earliest, and maca is improving men and women
Outstanding effect is shown in terms of sexual function, sperm quality, the increase for promoting ovum and vigor can not only be promoted, moreover it is possible to divide in adjusting
It secretes, enhancing energy, muscle power.
Donkey-hide gelatin, application have history in 3000, " panacea of enriching blood ", " nourishing national treasure " are always known as, with ginseng, pilose antler
It is known as together " Chinese medicine Triratna ".Donkey-hide gelatin contains a large amount of calcareous, is that health care for the middle and old aged institute is indispensable, in addition, donkey-hide gelatin is also
Can the absorption of calcium be promoted by the effect of glycine, internal calcium balance can be improved, so as to improve person in middle and old age because occurring during calcium deficiency
Various senility diseases.Donkey-hide gelatin can also stimulate body cell to generate SOD, and can improve the activity of SOD, and SOD can be removed
Oxygen radical has the function of nourish and beautify skin, slows down aging.Contribute to strengthening the muscles and bones, avoid osteoporosis, make joint flexible,
Make us the light body of body to be good for.To old and frail, weakness due to chronic disease easy catching a cold etc. has preferable treatment and prevention effect.
At present, the product in the prior art containing maca and Cordyceps militaris cannot well assist each ingredient in composition
Get up together, cause the waste of raw material.
Invention content
In order to overcome the above problem or solve the above problems at least partly, the present invention provides a kind of Cordyceps militaris containing maca
Composition, the composition by weight, is prepared by the raw material for including following component：10-30 parts of pueraria root powder, pupa worm
Careless 5-25 parts and 5-20 parts of donkey-hide gelatin.
Under the guidance of theory of traditional Chinese medical science, the present invention innovatively combines the pueraria root powder of specific components, Cordyceps militaris and donkey-hide gelatin
Together, the composition containing above-mentioned three components can give full play to the effect of various composition, while collaboration plays a role.
In order to further improve synergistic effect, it is preferred that 15-25 parts of pueraria root powder, 12-20 parts of Cordyceps militaris and donkey-hide gelatin 8-15
Part.More preferably, 10 parts of 20 parts of pueraria root powder, 15 parts of Cordyceps militaris and donkey-hide gelatin.
In order to further strengthen invigorating the spleen and conditioning, following component can also be included in the present compositions：Pueraria lobata, Fu
Siberian cocklebur, fructus cannabis and fresh Rhizoma Imperatae.
Above-mentioned 7 kinds of ingredients are combined, compared to single component, remittance is enriched blood, invigorating the spleen, eliminating evil and conditioning be in one, association
It is same to play a role.
In order to further improve enrich blood, invigorating the spleen, eliminating evil and conditioning effect, further include by weight, in raw material as follows
Component：5-20 parts of 5-20 parts of pueraria lobata, 5-20 parts of Poria cocos, 5-20 parts of fructus cannabis and fresh Rhizoma Imperatae.Preferably, pueraria lobata 8-15 parts,
8-15 parts of 8-15 parts of Poria cocos, 8-15 parts of fructus cannabis and fresh Rhizoma Imperatae.It is further preferably 10 parts of pueraria lobata, 10 parts of Poria cocos, fire fiber crops
10 parts of 10 parts of benevolence and fresh Rhizoma Imperatae.
When above-mentioned raw materials are as active constituent a period of time, optional and other active constituents, to obtain ideal collaboration
Effect.The composition of the present invention, preferably using above-mentioned raw materials as active constituent.
Composition of the present invention can be prepared into pressed candy, solid beverage, tea bag etc. via conventional method.It is excellent
It is selected as pressed candy.
When for pressed candy, the excipient that can be added in raw material or active constituent, such as isomalt and/or
Maltodextrin.
In the present compositions, when for pressed candy, composition is usually 0.5-0.8g/ pieces, every middle moisture
Content is 5-10%.Daily edible 1 time or multiple.
Tablet can also be further made to coating tablet, such as film-coating, sugar-coat etc..By prepare polymer substrate or
Using specific polymer in film coating, tablet can be made to quick-release, sustained release or controlled release form.Capsule can be soft capsule or
Hard shell capsules, without film or with film, so as to quick-release, sustained release or controlled release properties.
The composition of the present invention can be prepared in those skilled in the art using method commonly used in the art.
One aspect of the present invention additionally provides the preparation method of above-mentioned composition, by each component in raw material by proportioning
Mixing, ultramicro grinding.
One aspect of the present invention additionally provides another preparation method of above-mentioned composition, including：
Other raw materials in addition to the pueraria root powder of donkey-hide gelatin and half proportional quantity by proportioning are mixed, are added water to cook, concentration is dry
Dry, ultramicro grinding mixes the mixture after crushing with surplus stock.Wherein, water is preferably the 8-10 of mixed raw material total amount
Times, it decocts 2 times.
After obtaining mixed-powder, those skilled in the art can select auxiliary material according to demand.If it is made into tabletting
Mixed powder is usually added in the maltodextrin powder of 5-10%, the granulation of 70% alcohol, tabletting after drying by candy.
The present invention is based on the achievements in research of theory of traditional Chinese medical science, and pueraria root powder, Cordyceps militaris and donkey-hide gelatin are combined, obtained group
Close object remittance enrich blood, invigorating the spleen, eliminating evil, conditioning in a side, collaboration plays a role.
Specific embodiment
With reference to embodiment, the embodiment of the present invention is furthur described in detail.Following embodiment is used for
Illustrate the present invention, but be not limited to the scope of the present invention.Unless otherwise specified, technological means used is this field in embodiment
Conventional means known to technical staff, raw materials used is commercial goods.
Embodiment 1
1) take 20 parts of pueraria root powder, 15 parts of Cordyceps militaris, 10 parts of pueraria lobata, 10 parts of Poria cocos, 10 parts of fructus cannabis, 10 parts of fresh Rhizoma Imperatae,
10 parts of donkey-hide gelatin.Ultramicro grinding is spare.
2) above-mentioned raw materials are uniformly mixed, add in 5% maltodextrin, 70% alcohol granulation, drying to moisture
It is 5% or so, tabletting.Specification is 0.8g/ pieces.
Eating method：Twice a day, a two panels.
Embodiment 2
1) 10 parts of pueraria root powder, 15 parts of Cordyceps militaris, 10 parts of pueraria lobata, 10 parts of Poria cocos, 10 parts of fructus cannabis, 10 part 8 of fresh Rhizoma Imperatae are taken
The water of amount decocts 2 times again, and decocting liquid is concentrated and dried, and ultramicro grinding is spare.
2) 30 parts of isomalt, 10 parts of pueraria root powder, 10 parts of donkey-hide gelatin are taken.Above-mentioned raw materials are uniformly mixed, add in 5%
Maltodextrin, 70% alcohol granulation, drying to moisture are 5% or so, tabletting.Specification is 0.5g/ pieces.
Eating method：Twice a day, a two panels.
Embodiment 3
1) 10 parts of pueraria root powder, 5 parts of Cordyceps militaris, 5 parts of pueraria lobata, 5 parts of Poria cocos, 5 parts of fructus cannabis, 5 parts of fresh Rhizoma Imperatae, donkey-hide gelatin 5 are taken
Part.Ultramicro grinding is spare.
2) above-mentioned raw materials are uniformly mixed, add in 5% maltodextrin essence, 70% alcohol granulation is dried moisture and contained
It is 5% or so to measure, tabletting.Specification is 0.8g/ pieces.
Eating method：Twice a day, a two panels.
Embodiment 4
1) take 15 parts of pueraria root powder, 12 parts of Cordyceps militaris, 20 parts of pueraria lobata, 20 parts of Poria cocos, 20 parts of fructus cannabis, 20 parts of fresh Rhizoma Imperatae,
8 parts of donkey-hide gelatin.Ultramicro grinding is spare.
2) above-mentioned raw materials are uniformly mixed, add in 5% maltodextrin essence, 70% alcohol granulation is dried moisture and contained
It is 5% or so to measure, tabletting.Specification is 0.8g/ pieces.
Eating method：Twice a day, a two panels.
Embodiment 5
1) 20 parts of pueraria root powder, 15 parts of Cordyceps militaris, 8 parts of pueraria lobata, 8 parts of Poria cocos, 8 parts of fructus cannabis, 8 parts of fresh Rhizoma Imperatae, donkey-hide gelatin are taken
10 parts.Ultramicro grinding is spare.
2) above-mentioned raw materials are uniformly mixed, add in 5% maltodextrin, 70% alcohol granulation, drying to moisture
It is 5% or so, tabletting.Specification is 0.8g/ pieces.
Eating method：Twice a day, a two panels.
Embodiment 6
1) take 25 parts of pueraria root powder, 20 parts of Cordyceps militaris, 15 parts of pueraria lobata, 15 parts of Poria cocos, 15 parts of fructus cannabis, 15 parts of fresh Rhizoma Imperatae,
15 parts of donkey-hide gelatin.Ultramicro grinding is spare.
2) above-mentioned raw materials are uniformly mixed, add in 5% maltodextrin, 70% alcohol granulation, drying to moisture
It is 5% or so, tabletting.Specification is 0.8g/ pieces.
Eating method：Twice a day, a two panels.
Embodiment 7
1) take 30 parts of pueraria root powder, 25 parts of Cordyceps militaris, 20 parts of pueraria lobata, 20 parts of Poria cocos, 20 parts of fructus cannabis, 20 parts of fresh Rhizoma Imperatae,
20 parts of donkey-hide gelatin.Ultramicro grinding is spare.
2) above-mentioned raw materials are uniformly mixed, add in 5% maltodextrin, 70% alcohol granulation, drying to moisture
It is 5% or so, tabletting.Specification is 0.8g/ pieces.
Eating method：Twice a day, a two panels.
Comparative example 1
1) 20 parts of pueraria root powder, 10 parts of pueraria lobata, 10 parts of Poria cocos, 10 parts of fructus cannabis, 10 parts of fresh Rhizoma Imperatae, 10 parts of donkey-hide gelatin are taken.It is super
Crushing of Ultrafine is spare.
2) above-mentioned raw materials are uniformly mixed, add in 5% maltodextrin essence, 70% alcohol granulation is dried moisture and contained
It is 5% or so to measure, tabletting.Specification is 0.8g/ pieces.
Eating method：Twice a day, a two panels.
Comparative example 2
1) 20 parts of pueraria root powder, 15 parts of Cordyceps militaris, 10 parts of pueraria lobata, 10 parts of Poria cocos, 10 parts of fructus cannabis, 10 parts of fresh Rhizoma Imperatae are taken.
Ultramicro grinding is spare.
2) above-mentioned raw materials are uniformly mixed, add in 5% maltodextrin essence, 70% alcohol granulation is dried moisture and contained
It is 5% or so to measure, tabletting.Specification is 0.8g/ pieces.
Eating method：Twice a day, a two panels.
Comparative example 3
1) 5 parts of pueraria root powder, 30 parts of Cordyceps militaris, 10 parts of pueraria lobata, 10 parts of Poria cocos, 10 parts of fructus cannabis, 10 parts of fresh Rhizoma Imperatae, Ah are taken
20 parts of glue.Ultramicro grinding is spare.
2) above-mentioned raw materials are uniformly mixed, add in 5% maltodextrin essence, 70% alcohol granulation is dried moisture and contained
It is 5% or so to measure, tabletting.Specification is 0.8g/ pieces.
Eating method：Twice a day, a two panels.
Below by way of the qi-blood tonifying therapeutic effect of test example the present invention is furture elucidated the composition.
Test example one：
The tablet made to above example 1, finely ground to be dissolved in water, press human body recommended amounts respectively 5,10 and 20 times are molten
Solution, as test solution.The tablet made to more than comparative example 1, it is finely ground to be dissolved in water, it is molten by 20 times of human body recommended amounts
Solution, as test solution.Healthy adult ICR mouse 50 are taken, are divided into four groups, give the confession of above-mentioned 3 kinds of various concentrations respectively
Test sample solution and pure water.Daily using 0.2mL/10g solution as gastric infusion, after continuous 30 days, with reference to the Ministry of Public Health《Health food is examined
It tests and assessment technique specification 2003 editions》The method of inspection of middle function of physical fatigue alleviation experiment carries out the swimming with a load attached to the body of test mice
Time is detected.Experimental result is shown in the following table 1 for mice burden swimming.
1 mice burden swimming experimental result table of table
| Group | Quantity | Walking weight load (min) |
| Embodiment 1 (5 times of human body recommended amounts) | 10 | 25.5±3.6 |
| Embodiment 1 (10 times of human body recommended amounts) | 10 | 30.5±2.3 |
| Embodiment 1 (20 times of human body recommended amounts) | 10 | 35.2±3.4 |
| Comparative example 1 (20 times of human body recommended amounts) | 10 | 20.6±3.3 |
| Control group | 10 | 19.3±2.2 |
It is found that the mice burden swimming time of embodiment 1 is longer than 1 group of comparative example and control group, embodiment 1 from upper table 1
In the enhancing vitality effects of tablet be better than tablet and control group in comparative example 1.
Test example two：
Human body QI invigorating, the effect of beauty treatment to the above example 1-7 drugs prepared carry out clinical observation.
Efficacy assessment standard：
It is effective：Symptom disappears, energetic, and skin water profit is glossy, and of pink and healthy-looking, wrinkle, color spot are thin out, and skin is tight,
It sleeps, female menstrual period is regular.
Effectively：Symptom slows down, and spiritlessness and weakness sense is eliminated, and energetic vibrant, sleep quality is obviously improved, and face changes
Kind, wrinkle, color spot are thin out, and menstrual period are regular.
In vain：Treatment 2 months, symptom improve slightly or without improvement.
Choose 500：Through disease be diagnosed as coarse unglazed, the skin wrinkle of deficiency of vital energy and physically weak, spiritlessness and weakness, skin and color spot,
Ache all over, mammary development it is impacted, the patient of the severe primaries such as absent cardiovascular, liver, kidney disease and mental disease.By 500
10 groups are randomly divided into, every group 50, is controlled respectively using the drug of embodiment 1-7 and comparative example 1-3 according to eating method
Treat, and using its as test example 1, test example 2, test example 3, test example 4, test example 5, test example 6, test example 7, comparison
Example 1, comparative example 2 and comparative example 3.Statistical result such as the following table 2：
The treatment results of table 2 test example 1-7 and comparative example 1-3
| Number of cases | It is effective | Effectively | In vain | |
| Test example 1 | 50 | 10 | 33 | 7 |
| Test example 2 | 50 | 10 | 32 | 8 |
| Test example 3 | 50 | 7 | 30 | 13 |
| Test example 4 | 50 | 7 | 29 | 14 |
| Test example 5 | 50 | 6 | 30 | 14 |
| Test example 6 | 50 | 8 | 31 | 11 |
| Test example 7 | 50 | 8 | 32 | 10 |
| Comparative example 1 | 50 | 3 | 15 | 32 |
| Comparative example 2 | 50 | 2 | 12 | 36 |
| Comparative example 3 | 50 | 5 | 20 | 25 |
As can be seen that the bulk pharmaceutical chemicals in tablet prepared by the embodiment of the present invention after combining, produce association from upper table 2
Same-action, can preferably realize it is qi-blood tonifying, meanwhile, do not find that patient has taken in embodiment and has after drug in clinical process
Obvious adverse reaction.
Finally, method of the invention is only preferable embodiment, is not intended to limit the scope of the present invention.It is all
Within the spirit and principles in the present invention, any modification, equivalent replacement, improvement and so on should be included in the protection of the present invention
Within the scope of.
Claims (10)
1. the composition of a kind of Cordyceps militaris containing maca, which is characterized in that by weight, the composition is by including following component
Raw material be prepared：
5-20 parts of 10-30 parts of pueraria root powder, 5-25 parts of Cordyceps militaris and donkey-hide gelatin.
2. composition according to claim 1, which is characterized in that by weight, the composition is by including such as the following group
The raw material divided is prepared：
8-15 parts of 15-25 parts of pueraria root powder, 12-20 parts of Cordyceps militaris and donkey-hide gelatin.
3. composition according to claim 1, which is characterized in that by weight, the composition is by including such as the following group
The raw material divided is prepared：
10 parts of 20 parts of pueraria root powder, 15 parts of Cordyceps militaris and donkey-hide gelatin.
4. composition according to any one of claim 1-3, which is characterized in that further included in the raw material such as the following group
Point：Pueraria lobata, Poria cocos, fructus cannabis and fresh Rhizoma Imperatae.
5. composition according to claim 4, which is characterized in that by weight, further included in the raw material such as the following group
Point：
5-20 parts of 5-20 parts of pueraria lobata, 5-20 parts of Poria cocos, 5-20 parts of fructus cannabis and fresh Rhizoma Imperatae.
6. composition according to claim 5, which is characterized in that by weight, further included in the raw material such as the following group
Point：
8-15 parts of 8-15 parts of pueraria lobata, 8-15 parts of Poria cocos, 8-15 parts of fructus cannabis and fresh Rhizoma Imperatae.
7. according to the composition described in any one of claim 1-6, which is characterized in that the composition is pressed candy, admittedly
Body beverage or tea bag.
8. composition according to claim 7, which is characterized in that the composition be pressed candy, the pressed candy
Middle auxiliary material is isomalt and/or maltodextrin.
9. the preparation method of any one of the claim 1-8 compositions, including：
Each component in raw material is mixed by proportioning, ultramicro grinding.
10. the preparation method of any one of the claim 1-8 compositions, including：
Other raw materials in addition to the pueraria root powder of donkey-hide gelatin and half proportional quantity by proportioning are added water to cook respectively, is concentrated and dried, surpasses
Crushing of Ultrafine mixes the mixture after crushing with surplus stock.
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| CN1095902A (en) * | 1994-01-09 | 1994-12-07 | 河南省漯河市第一制药厂 | Cordyceps sinensis and donkey-hide gelatin nutrient solution |
| CN102599513A (en) * | 2012-03-26 | 2012-07-25 | 张丽琴 | Health food containing maca and Cordyceps sinensis |
| CN103251052A (en) * | 2013-05-23 | 2013-08-21 | 昆明宝特药用植物研究开发有限公司 | Lepidium meyenii walp and cordyceps militaris health-care food and preparation method thereof |
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| CN104256754A (en) * | 2014-02-14 | 2015-01-07 | 亳州市益寿轩药膳食品有限公司 | Maca healthcare solid beverage formula for women and preparing method thereof |
| CN104688797A (en) * | 2015-03-19 | 2015-06-10 | 沈阳伊人宝生化制品有限公司 | Cordyceps and maca tablet |
| CN105213454A (en) * | 2015-09-23 | 2016-01-06 | 东阿阿胶股份有限公司 | A kind of Colla Corii Asini Lepidinm meyenii Walp micropowder tablet and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1095902A (en) * | 1994-01-09 | 1994-12-07 | 河南省漯河市第一制药厂 | Cordyceps sinensis and donkey-hide gelatin nutrient solution |
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| CN103251052A (en) * | 2013-05-23 | 2013-08-21 | 昆明宝特药用植物研究开发有限公司 | Lepidium meyenii walp and cordyceps militaris health-care food and preparation method thereof |
| CN103393195A (en) * | 2013-08-08 | 2013-11-20 | 西藏现代农业有限公司 | Cordyceps beverage and preparation method thereof |
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