CN108186483A - A kind of natural ageing-resistant skin care composition and its application - Google Patents

A kind of natural ageing-resistant skin care composition and its application Download PDF

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CN108186483A
CN108186483A CN201810282709.3A CN201810282709A CN108186483A CN 108186483 A CN108186483 A CN 108186483A CN 201810282709 A CN201810282709 A CN 201810282709A CN 108186483 A CN108186483 A CN 108186483A
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extract
skin care
sodium
care compositions
leaf
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不公告发明人
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Foshan Charming Biotechnology Co Ltd
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Foshan Charming Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4993Derivatives containing from 2 to 10 oxyalkylene groups
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8158Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/927Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/524Preservatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention discloses a kind of natural ageing-resistant skin care composition, the skin care compositions contains raw material as described below:List hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry berry extract;The list hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry berry extract mass ratio be (1 10):(1‑10):(1‑10):(1‑10).Skin care compositions of the present invention can effectively promote moisture content of skin, promote collagen generation, the improvement colour of skin obscure, effectively resist the light aging of skin.

Description

A kind of natural ageing-resistant skin care composition and its application
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of natural ageing-resistant skin care composition and its application.
Background technology
Since in residing environment of living, air dries dirt, the interference of ultraviolet light, operating pressure, rhythm of life etc. The influence of factor, people usually will appear skin dull, coarse too early, jaundice, long wrinkle or even color spot, chloasma etc. occur Light senile symptom.And it is that each people seeking beauty is desired to possess bright pale skin.It is light therefore, it is possible to resist above-mentioned skin The cosmetics of aging will have good market prospects.
Invention content
The technical problem to be solved in the present invention is to provide a kind of natural ageing-resistant skin care compositions.Skin care compositions of the present invention Moisture content of skin can effectively be promoted, promote collagen generation, the improvement colour of skin obscure, effectively resist the light aging of skin.
Specific technical solution of the present invention is as follows:
A kind of natural ageing-resistant skin care composition, contains raw material as described below:List hawthorne leaf P.E, Fructus Malvae Vertillatae carry Take object, Chinese ilex leaf extract, great bilberry berry extract;The list hawthorne leaf P.E, Fructus Malvae extract, leaf of Chinese ilex Extract, great bilberry berry extract mass ratio be (1-10):(1-10):(1-10):(1-10).
In wherein some embodiments, the skin care compositions also contains raw material as described below:Fructus Canarii extract loses Sauce grass extract, mulberries extract, Rocket ram jet extract;The Fructus Canarii extract, Herba Patriniae extract, mulberries extract, The mass ratio of Rocket ram jet extract is (1-10):(1-10):(1-10):(1-10).
In wherein some embodiments, the list hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, Great bilberry berry extract, Fructus Canarii extract, Herba Patriniae extract, mulberries extract, the mass ratio of Rocket ram jet extract are (1-10):(1-10):(1-10):(1-10):(1-10):(1-10):(1-10):(1-10).
The present invention also provides application of the skin care compositions in cosmetics are prepared, wherein, the skincare composition The dosage of object is the 0.01-10% of final products dosage.
The present invention also provides a kind of Essence, each component containing following mass percent:Above-mentioned skin care compositions 0.01- 10%th, glycerine 1-10%, butanediol 1-5%, sodium hydroxyethyl cellulose 0.1-0.3%, oligofructose 0.1-0.5%, hyalomitome Sour sodium 0.01-0.05%, EDETATE SODIUM 0.01-0.05%, methyl propanediol 1-3%, dipotassium glycyrrhizinate 0.05-0.15%, cigarette Amide 1-5%, glycerine polymethacrylates 0.1-0.5%, ethylhexyl methoxy cinnamate 0.1-0.5%, PEG-100 are hard It is the smooth stearate 0.1-0.3% of resin acid ester 0.1-0.5%, Polyoxyethylene Sorbitan Monooleate 0.5-1%, sorb, saualane 1-10%, pungent Base lauryl alcohol myristinate 1-5%, caprylic/capric triglyceride 1-5%, isohexadecane 1-5%, sodium acrylate/acryloyl Dimethyltaurine sodium copolymer 0.1-0.5%, cetostearyl alcohol 0.5-1.5%, Butyrospermum parkii fruit fat 0.1-1%, phenyl three Methylsiloxane 0.5-2.5%, beeswax 0.1-1%, tocopherol acetate 0.1-1%, preservative 0.3-0.6%, arginine 0.1-0.3%, propolis extract 0.1-1%, water surplus.
In wherein some embodiments, mixing of the preservative for polyquaternium -15 and 1,2- hexylene glycol.
In wherein some embodiments, the mass ratio of the polyquaternium -15 and 1,2- hexylene glycol is 1:3.The present invention By polyquaternium -15 and 1,2- hexylene glycols are combined by specific proportioning, can dramatically increase the antisepsis and sterilization effect of Essence, and temperature With it is non-stimulated.Compared with being used alone, 1,2- hexylene glycols are better.
In wherein some embodiments, the preparation method of the Essence includes the following steps:
1st, by glycerine polymethacrylates, ethylhexyl methoxy cinnamate, PEG-100 stearates, polysorbate The smooth stearate of ester -80, sorb, saualane, octyl dodecanol myristinate, caprylic/capric triglyceride, isohexadecane, Sodium acrylate/sodium acryloyldimethyl taurate copolymers, cetostearyl alcohol, Butyrospermum parkii fruit fat, Silicone DC 556, Beeswax, tocopherol acetate input oil phase pot, are heated to 80 DEG C, oil phase are made, spare as B;2nd, by glycerine, butanediol, hydroxyl Ethyl cellulose sodium, oligofructose, Sodium Hyaluronate, EDETATE SODIUM, methyl propanediol, dipotassium glycyrrhizinate, niacinamide, water input Pot is emulsified, is heated to 80 DEG C, transparent aqueous phase is made in 2000rpm homogenous disperses 3-5 minutes, 20 minutes is kept the temperature, as A phases;3rd, will B phases are pumped into emulsification pot, and 3000rpm homogeneous 3-5 minutes stirs lower heat preservation 20 minutes;4th, 45 DEG C are cooled to, input preservative, essence Propylhomoserin, propolis extract, above-mentioned skin care compositions, 2000rpm homogenous disperses 1-2 minutes, stir evenly;Room temperature is cooled to, is gone out Material.
Compared with prior art, the invention has the advantages that:
The skin care compositions of light aging of the invention can effectively promote moisture content of skin, promote collagen generation, improve The colour of skin is obscure, effectively resists the light aging of skin.
It is stearic that Essence of the present invention has compounded glycerine polymethacrylates, ethylhexyl methoxy cinnamate, PEG-100 Acid esters, Polyoxyethylene Sorbitan Monooleate, sorb five kinds of emulsifiers of smooth stearate, on the basis of good product stability is obtained, Obtain excellent product use feeling.Methyl propanediol and octyl dodecanol myristinate have been compounded, has been conducive in product Functional component penetrates into skin cuticula;Propolis extract has been compounded, has been conducive to remove old useless cutin, promotes cuticula more Newly;Beeswax, niacinamide, oligofructose, Butyrospermum parkii fruit fat have been compounded, sufficient nutriment is provided for skin, has promoted skin Metabolism, the various raw materials of Essence of the present invention have their own characteristics each, mutually promote, and realize collaboration resists skin The effect of light aging.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below Step ground detailed description, but the implementation of the present invention is not limited to this, for especially not dated technological parameter or condition, can refer to Routine techniques carries out.
Involved each ingredient is described as follows in skin care compositions of the present invention:
List hawthorne leaf P.E:Rose family Maloideae hawthorn is mainly distributed on north temperate zone about 30 ° of north latitude The ground such as~50 ° of East Asia, Europe, North America.Rich in a large amount of polyatomic phenol ingredient in leaf, wherein general flavone amount is about 1.5%.It is more First phenols component, which has, removes free radical, antioxidation, wherein Quercetin, chlorogenic acid, epicatechin, Hyperoside and rutin It is stronger than the antioxidant activity of other compositions.This shows the polyatomic phenol platform object with adjacent two phenolic hydroxyl structures, there is very strong resist Oxidability;Adjacent two phenolic hydroxyl groups are its anti-oxidant, scavenging activated oxygen chief active positions.Phenolic compound and oxygen radical Reaction half quinoid structure of generation, due to the presence of adjacent two phenolic hydroxyl groups, half quinoid structure is stablized relatively, therefore shows stronger anti- Oxidation activity.
Dry mature fruit of the Fructus Malvae Vertillatae for malvaceae plant winter certain herbaceous plants with big flowers, alias:Malva leaf, sliding cauliflower, certain herbaceous plants with big flowers, certain herbaceous plants with big flowers vegetable seeds. Fructus Malvae Vertillatae polysaccharide is obtained by Fructus Malvae Vertillatae extraction purification, has scavenging effect to hydroxy radical, ultra-oxygen anion free radical.Fructus Malvae Vertillatae Also containing amino acid, protein, polypeptide, tannin, phenols, triterpene, flavonoids, the chemical compositions such as steroidal, mucilaginous substance, there is antioxygen Change, it is antibacterial and immune the effects that.
Chinese ilex leaf extract:Chinese ilex department aiphyllium is tropical trees, is mainly distributed on China middle and lower reach of Yangtze River stream Domain and southwestern part provinces and regions, resource very abundant are the wild natural pharmaceutical resources that a kind of worth Devoting Major Efforts To Developing utilizes.Leaf of Chinese ilex Extract have the effects that significant antibacterial, it is anti-oxidant, decompression, fat-eliminating slimming, active constituent be mainly flavonoids, Polyphenols and The chemical compositions such as the fragrant plain class of saponin, beans.Wherein flavones and polyphenol have the work of stronger removing DPPH free radicals and hydroxy radical With adding it to has skin whitening, anti-aging effect in cosmetics.
Great bilberry be also known as bog bilberry, black soya bean tree (Daxing'an Mountainrange), pasture fruit, fruit (Jilin, near a river), Long Guo, be azalea Section's genus vaccinium machaka.Great bilberry is mainly distributed on the areas such as the Inner Mongol, Heilungkiang, Jilin, Liaoning in China.Bog bilberry is got over Tangerine extract has removes by force free radical and anti-oxidation function very much, has anti-aging, coordinated balance and enhancing memory effect;Tool There is stable collagen and promote collagen synthesis effect;With reduction capillary permeability and inhibit platelet aggregation; Synthesis and release with prevention prostaglandin, leukotrienes class and histamine;Flavone compound in great bilberry leaf, With removing toxic substances, diuresis, reduces blood glucose and other effects at anti-inflammatory.
Chinese olive, alias olive, be south China famous and high-quality fruit, have promote the production of body fluid to quench thirst, open taste, is aid digestion, solution controls larynx Disease etc. is medicinal and health-care efficacy.The a variety of chemical compositions contained in Chinese olive have higher pharmacological activity, particularly can wherein carry The hepatocuprein of separation greater activity is taken, is the natural scavenger of O2- in body, protection cell, anti-aging can be played Effect, the peroxidase and hydrogen peroxide of the similary inhibiting effect with hydroxyl radical free radical scavenging effect and superoxide radical Enzyme, this 3 kinds of antioxidases have mutually coordinated effect in removing machine body during injury caused by extra superoxide anion.
Field pennycress, also known as pool lose, bitter dish etc., belong to Valerianaceae herbaceos perennial.It is China's conventional Chinese medicine, is had clear The effect of thermal detoxification.Research shows that Herba Patriniae extract contains higher flavones, saponin(e isoreactivity substance, have to hydroxy radical Stronger scavenging effect also has ultra-oxygen anion free radical certain scavenging effect, can be as natural anti-aging cosmetics.
Mulberries are the fruits of Moraceae Morus perennial woody plant mulberry tree.Mulberries extract is also referred to as mulberry red pigment, it contains There are the ingredients such as abundant activated protein, vitamin, amino acid, malic acid, main component is anthocyanin.Nutritional ingredient is grape 4 times, 5~6 times of apple, there are multiple efficacies, be described as " the best health fruit of 21st century " by medical field.Mulberries, which have, to be changed The blood supply of kind skin, nutrition skin make skin delicate and the effects that black hair, and can slow down aging.Mulberries polysaccharide can be clear Except free radical, radical reaction chain is blocked, there is certain anti-oxidant and anti-aging effect.
Rocket ram jet extract:Fiery spine is rose family Pyracantha plant, is widely distributed in China, isolates to obtain about 30 at present Kind flavone compound, aglycon are mainly Kaempferol, Quercetin, naringenin, apiolin etc., and common sugar is rhamnose, Portugal Grape sugar, arabinose, galactolipin have been shown to have scavenging activated oxygen, reducing blood lipid, strengthen immunity, enhancing muscle power and rush The effects that into digestive function.Flavone compound, which has, inhibits tyrosinase effect, shows stronger whitening active, therefore make For a kind of new natural whitening agent, Rocket ram jet has huge potentiality to be exploited.
Embodiment 1
A kind of Essence, each component containing following mass percent:Skin care compositions 1%, glycerine 5%, butanediol 3%th, sodium hydroxyethyl cellulose 0.2%, oligofructose 0.25%, Sodium Hyaluronate 0.03%, EDETATE SODIUM 0.03%, methyl-prop Glycol 2%, dipotassium glycyrrhizinate 0.1%, niacinamide 3%, glycerine polymethacrylates 0.3%, methoxy cinnamic acid ethyl hexyl The smooth stearate 0.2% of ester 0.3%, PEG-100 stearates 0.3%, Polyoxyethylene Sorbitan Monooleate 0.85%, sorb, saualane 5%th, octyl dodecanol myristinate 2.5%, caprylic/capric triglyceride 2.5%, isohexadecane 2.5%, sodium acrylate/ Sodium acryloyldimethyl taurate copolymers 0.25%, cetostearyl alcohol 1%, Butyrospermum parkii fruit fat 0.5%, phenyl trimethicone silicon Oxygen alkane 1.5%, beeswax 0.5%, tocopherol acetate 0.5%, preservative 0.4%, arginine 0.2%, propolis extract 0.5%th, water surplus.
The skin care compositions is by list hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry fruit Extract is 7 by mass ratio:3:4:5 compositions.
It by mass ratio is 1 that the preservative, which is polyquaternium -15 and 1,2- hexylene glycols,:3 compositions.
The preparation method of the Essence includes the following steps:1st, by glycerine polymethacrylates, methoxy cinnamic acid Ethylhexyl, PEG-100 stearates, Polyoxyethylene Sorbitan Monooleate, the smooth stearate of sorb, saualane, octyl dodecanol nutmeg Acid esters, caprylic/capric triglyceride, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, cetearyl alcohol Alcohol, Butyrospermum parkii fruit fat, Silicone DC 556, beeswax, tocopherol acetate input oil phase pot, are heated to 80 DEG C, are made Oil phase, it is spare as B;2nd, by glycerine, butanediol, sodium hydroxyethyl cellulose, oligofructose, Sodium Hyaluronate, EDETATE SODIUM, first Base propylene glycol, dipotassium glycyrrhizinate, niacinamide, water input emulsification pot, are heated to 80 DEG C, 2000rpm homogenous disperses 4 minutes are made Transparent aqueous phase keeps the temperature 20 minutes, as A phases;3rd, B phases are pumped into emulsification pot, 3000rpm homogeneous 3 minutes stirs lower 20 points of heat preservation Clock;4th, 45 DEG C are cooled to, puts into preservative, arginine, propolis extract, above-mentioned skin care compositions, 2000rpm homogenous disperses 1 Minute, it stirs evenly;Room temperature is cooled to, is discharged.
Embodiment 2
A kind of Essence, each component containing following mass percent:Skin care compositions 0.01%, glycerine 8%, butanediol 5%th, sodium hydroxyethyl cellulose 0.1%, oligofructose 0.5%, Sodium Hyaluronate 0.05%, EDETATE SODIUM 0.01%, methyl-prop Glycol 1%, dipotassium glycyrrhizinate 0.15%, niacinamide 5%, glycerine polymethacrylates 0.1%, methoxy cinnamic acid ethyl hexyl The smooth stearate 0.1% of ester 0.5%, PEG-100 stearates 0.5%, Polyoxyethylene Sorbitan Monooleate 1%, sorb, saualane 10%, Octyl dodecanol myristinate 1%, caprylic/capric triglyceride 5%, isohexadecane 1%, sodium acrylate/acryloyl diformazan Base Taurate Copolymer 0.5%, cetostearyl alcohol 1.5%, Butyrospermum parkii fruit fat 0.1%, Silicone DC 556 2.5%th, beeswax 0.1%, tocopherol acetate 1%, preservative 0.3%, arginine 0.3%, propolis extract 1%, water surplus.
The skin care compositions is by list hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry fruit Extract is 10 by mass ratio:1:1:10 compositions.
It by mass ratio is 1 that the preservative, which is polyquaternium -15 and 1,2- hexylene glycols,:3 compositions.
The preparation method of the Essence includes the following steps:1st, by glycerine polymethacrylates, methoxy cinnamic acid Ethylhexyl, PEG-100 stearates, Polyoxyethylene Sorbitan Monooleate, the smooth stearate of sorb, saualane, octyl dodecanol nutmeg Acid esters, caprylic/capric triglyceride, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, cetearyl alcohol Alcohol, Butyrospermum parkii fruit fat, Silicone DC 556, beeswax, tocopherol acetate input oil phase pot, are heated to 80 DEG C, are made Oil phase, it is spare as B;2nd, by glycerine, butanediol, sodium hydroxyethyl cellulose, oligofructose, Sodium Hyaluronate, EDETATE SODIUM, first Base propylene glycol, dipotassium glycyrrhizinate, niacinamide, water input emulsification pot, are heated to 80 DEG C, 2000rpm homogenous disperses 5 minutes are made Transparent aqueous phase keeps the temperature 20 minutes, as A phases;3rd, B phases are pumped into emulsification pot, 3000rpm homogeneous 3 minutes stirs lower 20 points of heat preservation Clock;4th, 45 DEG C are cooled to, puts into preservative, arginine, propolis extract, above-mentioned skin care compositions, 2000rpm homogenous disperses 2 Minute, it stirs evenly;Room temperature is cooled to, is discharged.
Embodiment 3
A kind of Essence, each component containing following mass percent:Skin care compositions 10%, glycerine 1%, butanediol 1%th, sodium hydroxyethyl cellulose 0.3%, oligofructose 0.1%, Sodium Hyaluronate 0.01%, EDETATE SODIUM 0.05%, methyl-prop Glycol 3%, dipotassium glycyrrhizinate 0.05%, niacinamide 1%, glycerine polymethacrylates 0.5%, methoxy cinnamic acid ethyl hexyl The smooth stearate 0.3% of ester 0.1%, PEG-100 stearates 0.1%, Polyoxyethylene Sorbitan Monooleate 0.5%, sorb, saualane 1%th, octyl dodecanol myristinate 5%, caprylic/capric triglyceride 1%, isohexadecane 5%, sodium acrylate/acryloyl Dimethyltaurine sodium copolymer 0.1%, cetostearyl alcohol 0.5%, Butyrospermum parkii fruit fat 1%, Silicone DC 556 0.5%th, beeswax 1%, tocopherol acetate 0.1%, preservative 0.6%, arginine 0.1%, propolis extract 0.1%, more than water Amount.
The skin care compositions is by list hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry fruit Extract is 1 by mass ratio:10:10:1 composition.
It by mass ratio is 1 that the preservative, which is polyquaternium -15 and 1,2- hexylene glycols,:3 compositions.
The preparation method of the Essence includes the following steps:1st, by glycerine polymethacrylates, methoxy cinnamic acid Ethylhexyl, PEG-100 stearates, Polyoxyethylene Sorbitan Monooleate, the smooth stearate of sorb, saualane, octyl dodecanol nutmeg Acid esters, caprylic/capric triglyceride, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, cetearyl alcohol Alcohol, Butyrospermum parkii fruit fat, Silicone DC 556, beeswax, tocopherol acetate input oil phase pot, are heated to 80 DEG C, are made Oil phase, it is spare as B;2nd, by glycerine, butanediol, sodium hydroxyethyl cellulose, oligofructose, Sodium Hyaluronate, EDETATE SODIUM, first Base propylene glycol, dipotassium glycyrrhizinate, niacinamide, water input emulsification pot, are heated to 80 DEG C, 2000rpm homogenous disperses 3 minutes are made Transparent aqueous phase keeps the temperature 20 minutes, as A phases;3rd, B phases are pumped into emulsification pot, 3000rpm homogeneous 3 minutes stirs lower 20 points of heat preservation Clock;4th, 45 DEG C are cooled to, puts into preservative, arginine, propolis extract, above-mentioned skin care compositions, 2000rpm homogenous disperses 1 Minute, it stirs evenly;Room temperature is cooled to, is discharged.
Embodiment 4
A kind of Essence, each component containing following mass percent:Skin care compositions 3%, glycerine 3%, butanediol 4%th, sodium hydroxyethyl cellulose 0.25%, oligofructose 0.35%, Sodium Hyaluronate 0.02%, EDETATE SODIUM 0.02%, methyl Propylene glycol 2.5%, dipotassium glycyrrhizinate 0.08%, niacinamide 4%, glycerine polymethacrylates 0.2%, methoxy cinnamic acid second The own ester 0.4% of base, PEG-100 stearates 0.3%, Polyoxyethylene Sorbitan Monooleate 0.8%, the smooth stearate 0.25% of sorb, spiny dogfish Alkane 8%, octyl dodecanol myristinate 4%, caprylic/capric triglyceride 3%, isohexadecane 2%, sodium acrylate/propylene Acyl dimethyltaurine sodium copolymer 0.3%, cetostearyl alcohol 0.9%, Butyrospermum parkii fruit fat 0.8%, phenyl trimethicone silica Alkane 1.5%, beeswax 0.7%, tocopherol acetate 0.6%, preservative 0.5%, arginine 0.25%, propolis extract 0.7%, Water surplus.
The skin care compositions is by list hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry fruit Extract, Fructus Canarii extract, Herba Patriniae extract, mulberries extract, Rocket ram jet extract are 7 by mass ratio:3:4:5:4: 3:7:5 compositions.
It by mass ratio is 1 that the preservative, which is polyquaternium -15 and 1,2- hexylene glycols,:3 compositions.
The preparation method of the Essence includes the following steps:1st, by glycerine polymethacrylates, methoxy cinnamic acid Ethylhexyl, PEG-100 stearates, Polyoxyethylene Sorbitan Monooleate, the smooth stearate of sorb, saualane, octyl dodecanol nutmeg Acid esters, caprylic/capric triglyceride, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, cetearyl alcohol Alcohol, Butyrospermum parkii fruit fat, Silicone DC 556, beeswax, tocopherol acetate input oil phase pot, are heated to 80 DEG C, are made Oil phase, it is spare as B;2nd, by glycerine, butanediol, sodium hydroxyethyl cellulose, oligofructose, Sodium Hyaluronate, EDETATE SODIUM, first Base propylene glycol, dipotassium glycyrrhizinate, niacinamide, water input emulsification pot, are heated to 80 DEG C, 2000rpm homogenous disperses 5 minutes are made Transparent aqueous phase keeps the temperature 20 minutes, as A phases;3rd, B phases are pumped into emulsification pot, 3000rpm homogeneous 4 minutes stirs lower 20 points of heat preservation Clock;4th, 45 DEG C are cooled to, puts into preservative, arginine, propolis extract, above-mentioned skin care compositions, 2000rpm homogenous disperses 2 Minute, it stirs evenly;Room temperature is cooled to, is discharged.
Embodiment 5
A kind of Essence, each component containing following mass percent:Skin care compositions 0.5%, glycerine 6%, butanediol 3%th, sodium hydroxyethyl cellulose 0.15%, oligofructose 0.45%, Sodium Hyaluronate 0.03%, EDETATE SODIUM 0.04%, methyl Propylene glycol 1.5%, dipotassium glycyrrhizinate 0.09%, niacinamide 3.5%, glycerine polymethacrylates 0.4%, methoxy cinnamic acid The smooth stearate 0.3% of ethylhexyl 0.2%, PEG-100 stearates 0.3%, Polyoxyethylene Sorbitan Monooleate 0.8%, sorb, angle Shark alkane 7%, octyl dodecanol myristinate 4%, caprylic/capric triglyceride 2%, isohexadecane 3%, sodium acrylate/the third Alkene acyl dimethyltaurine sodium copolymer 0.3%, cetostearyl alcohol 0.9%, Butyrospermum parkii fruit fat 0.6%, phenyl trimethicone silicon Oxygen alkane 2%, beeswax 0.7%, tocopherol acetate 0.4%, preservative 0.4%, arginine 0.2%, propolis extract 0.8%, Water surplus.
The skin care compositions is by list hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry fruit Extract, Fructus Canarii extract, Herba Patriniae extract, mulberries extract, Rocket ram jet extract are 10 by mass ratio:10:1:1: 10:1:10:1 composition.
It by mass ratio is 1 that the preservative, which is polyquaternium -15 and 1,2- hexylene glycols,:3 compositions.
The preparation method of the Essence includes the following steps:1st, by glycerine polymethacrylates, methoxy cinnamic acid Ethylhexyl, PEG-100 stearates, Polyoxyethylene Sorbitan Monooleate, the smooth stearate of sorb, saualane, octyl dodecanol nutmeg Acid esters, caprylic/capric triglyceride, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, cetearyl alcohol Alcohol, Butyrospermum parkii fruit fat, Silicone DC 556, beeswax, tocopherol acetate input oil phase pot, are heated to 80 DEG C, are made Oil phase, it is spare as B;2nd, by glycerine, butanediol, sodium hydroxyethyl cellulose, oligofructose, Sodium Hyaluronate, EDETATE SODIUM, first Base propylene glycol, dipotassium glycyrrhizinate, niacinamide, water input emulsification pot, are heated to 80 DEG C, 2000rpm homogenous disperses 5 minutes are made Transparent aqueous phase keeps the temperature 20 minutes, as A phases;3rd, B phases are pumped into emulsification pot, 3000rpm homogeneous 5 minutes stirs lower 20 points of heat preservation Clock;4th, 45 DEG C are cooled to, puts into preservative, arginine, propolis extract, above-mentioned skin care compositions, 2000rpm homogenous disperses 1 Minute, it stirs evenly;Room temperature is cooled to, is discharged.
Embodiment 6
A kind of Essence, each component containing following mass percent:Skin care compositions 7%, glycerine 6%, butanediol 2%th, sodium hydroxyethyl cellulose 0.16%, oligofructose 0.37%, Sodium Hyaluronate 0.03%, EDETATE SODIUM 0.02%, methyl Propylene glycol 1.7%, dipotassium glycyrrhizinate 0.08%, niacinamide 2.6%, glycerine polymethacrylates 0.4%, methoxy cinnamic acid The smooth stearate 0.2% of ethylhexyl 0.36%, PEG-100 stearates 0.4%, Polyoxyethylene Sorbitan Monooleate 0.6%, sorb, angle Shark alkane 6%, octyl dodecanol myristinate 4%, caprylic/capric triglyceride 3%, isohexadecane 2%, sodium acrylate/the third Alkene acyl dimethyltaurine sodium copolymer 0.4%, cetostearyl alcohol 0.7%, Butyrospermum parkii fruit fat 0.8%, phenyl trimethicone silicon Oxygen alkane 2%, beeswax 0.6%, tocopherol acetate 0.4%, preservative 0.5%, arginine 0.1%, propolis extract 0.7%, Water surplus.
The skin care compositions is by list hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry fruit Extract, Fructus Canarii extract, Herba Patriniae extract, mulberries extract, Rocket ram jet extract are 1 by mass ratio:1:10:10: 1:10:1:10 compositions.
It by mass ratio is 1 that the preservative, which is polyquaternium -15 and 1,2- hexylene glycols,:3 compositions.
The preparation method of the Essence includes the following steps:1st, by glycerine polymethacrylates, methoxy cinnamic acid Ethylhexyl, PEG-100 stearates, Polyoxyethylene Sorbitan Monooleate, the smooth stearate of sorb, saualane, octyl dodecanol nutmeg Acid esters, caprylic/capric triglyceride, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, cetearyl alcohol Alcohol, Butyrospermum parkii fruit fat, Silicone DC 556, beeswax, tocopherol acetate input oil phase pot, are heated to 80 DEG C, are made Oil phase, it is spare as B;2nd, by glycerine, butanediol, sodium hydroxyethyl cellulose, oligofructose, Sodium Hyaluronate, EDETATE SODIUM, first Base propylene glycol, dipotassium glycyrrhizinate, niacinamide, water input emulsification pot, are heated to 80 DEG C, 2000rpm homogenous disperses 4 minutes are made Transparent aqueous phase keeps the temperature 20 minutes, as A phases;3rd, B phases are pumped into emulsification pot, 3000rpm homogeneous 4 minutes stirs lower 20 points of heat preservation Clock;4th, 45 DEG C are cooled to, puts into preservative, arginine, propolis extract, above-mentioned skin care compositions, 2000rpm homogenous disperses 2 Minute, it stirs evenly;Room temperature is cooled to, is discharged.
Comparative example 1
Difference lies in be not added with list hawthorne leaf P.E with embodiment 1.
Comparative example 2
Difference lies in be not added with Fructus Malvae extract with embodiment 1.
Comparative example 3
Difference lies in be not added with Chinese ilex leaf extract with embodiment 1.
Comparative example 4
Difference lies in be not added with great bilberry berry extract with embodiment 1.
Comparative example 5
Difference lies in be not added with Fructus Canarii extract with embodiment 4.
Comparative example 6
Difference lies in be not added with Herba Patriniae extract with embodiment 4.
Comparative example 7
Difference lies in be not added with mulberries extract with embodiment 4.
Comparative example 8
Difference lies in be not added with Rocket ram jet extract with embodiment 4.
Detection result on probation is carried out to the embodiment 1-6 and comparative example 1-8 lotions prepared.
Test object:Each experimental group is 20 women (25-50 Sui);
Test zone:Inner forearm and crows feet area;
It uses:Twice daily, persistently using 4 weeks;
Test event:Humidity of skin, the colour of skin are obscure, the soft degree of skin, wrinkle of skin.
Result on trial is shown in Table 1.
As can be seen from Table 1, the Essence obtained by embodiment 1-6 has good moisturizing, whitening, crease-resistant and anti-aging Effect.
Comparative example 1-4 and embodiment 1-3 is compared as it can be seen that list hawthorne leaf P.E, Fructus Malvae extract, leaf of Chinese ilex extract Object, great bilberry berry extract are that Essence plays moisturizing, whitening, crease-resistant and anti-aging effects key component, and list mountain The effect of Essence is just bright when short, bristly hair or beard leaf extract, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry berry extract share It is aobvious, embody synergistic function.
Embodiment 4-6 and embodiment 1-3 is compared as it can be seen that Fructus Canarii extract, Herba Patriniae extract, mulberries extract, fiery spine The addition of berry extract significantly improves the moisturizing, whitening, crease-resistant and anti-aging effect of the Essence;And comparative example 5- 8 compare with embodiment 4-6 as it can be seen that when Fructus Canarii extract, Herba Patriniae extract, mulberries extract, Rocket ram jet extract share Promotion effect can be embodied, there is synergy.
The above described is only a preferred embodiment of the present invention, limitation in any form is not done to the present invention, therefore All contents without departing from technical solution of the present invention, technical spirit according to the present invention is made to the above embodiment any simply to repair Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.

Claims (8)

1. a kind of natural ageing-resistant skin care composition, which is characterized in that the skin care compositions contains raw material as described below: List hawthorne leaf P.E, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry berry extract;The list leaves of Hawthorn Extract, Fructus Malvae extract, Chinese ilex leaf extract, great bilberry berry extract mass ratio be (1-10):(1-10): (1-10):(1-10).
2. skin care compositions according to claim 1, which is characterized in that the skin care compositions is also containing as described below Raw material:Fructus Canarii extract, Herba Patriniae extract, mulberries extract, Rocket ram jet extract;The Fructus Canarii extract, Patrinia scaniosaefolia Careless extract, mulberries extract, the mass ratio of Rocket ram jet extract are (1-10):(1-10):(1-10):(1-10).
3. skin care compositions according to claim 1 or 2, which is characterized in that the list hawthorne leaf P.E, winter certain herbaceous plants with big flowers Berry extract, Chinese ilex leaf extract, great bilberry berry extract, Fructus Canarii extract, Herba Patriniae extract, mulberries extract, fire The mass ratio of spine berry extract is (1-10):(1-10):(1-10):(1-10):(1-10):(1-10):(1-10):(1- 10)。
4. according to application of the claim 1-3 any one of them skin care compositions in cosmetics are prepared, wherein, the skin care The dosage of composition is the 0.01-10% of final products dosage.
A kind of 5. Essence, which is characterized in that each component containing following mass percent:Such as any one of claim 1-3 institutes The skin care compositions 0.01-10% that states, glycerine 1-10%, butanediol 1-5%, sodium hydroxyethyl cellulose 0.1-0.3%, oligomeric fruit Sugared 0.1-0.5%, Sodium Hyaluronate 0.01-0.05%, EDETATE SODIUM 0.01-0.05%, methyl propanediol 1-3%, glycyrrhizic acid Dipotassium 0.05-0.15%, niacinamide 1-5%, glycerine polymethacrylates 0.1-0.5%, ethylhexyl methoxy cinnamate The smooth stearate 0.1- of 0.1-0.5%, PEG-100 stearate 0.1-0.5%, Polyoxyethylene Sorbitan Monooleate 0.5-1%, sorb 0.3%th, saualane 1-10%, octyl dodecanol myristinate 1-5%, caprylic/capric triglyceride 1-5%, isohexadecane 1-5%, sodium acrylate/sodium acryloyldimethyl taurate copolymers 0.1-0.5%, cetostearyl alcohol 0.5-1.5%, butter fruit Set fruit fat 0.1-1%, Silicone DC 556 0.5-2.5%, beeswax 0.1-1%, tocopherol acetate 0.1-1%, anti-corrosion Agent 0.3-0.6%, arginine 0.1-0.3%, propolis extract 0.1-1%, water surplus.
6. Essence according to claim 5, which is characterized in that the preservative for polyquaternium -15 and 1,2- oneself two The mixing of alcohol.
7. Essence according to claim 6, which is characterized in that the quality of the polyquaternium -15 and 1,2- hexylene glycol The ratio between be 1:3.
8. Essence according to claim 5, which is characterized in that the preparation method of the Essence includes the following steps: 1st, by glycerine polymethacrylates, ethylhexyl methoxy cinnamate, PEG-100 stearates, Polyoxyethylene Sorbitan Monooleate, mountain The smooth stearate of pears, saualane, octyl dodecanol myristinate, caprylic/capric triglyceride, isohexadecane, sodium acrylate/ Sodium acryloyldimethyl taurate copolymers, cetostearyl alcohol, Butyrospermum parkii fruit fat, Silicone DC 556, beeswax, fertility Phenol acetic acid esters puts into oil phase pot, is heated to 80 DEG C, and oil phase is made, spare as B;2nd, by glycerine, butanediol, hydroxyethyl cellulose Sodium, oligofructose, Sodium Hyaluronate, EDETATE SODIUM, methyl propanediol, dipotassium glycyrrhizinate, niacinamide, water input emulsification pot, add For heat to 80 DEG C, transparent aqueous phase is made in 2000rpm homogenous disperses 3-5 minutes, 20 minutes is kept the temperature, as A phases;3rd, B phases are pumped into breast Change pot, 3000rpm homogeneous 3-5 minutes stirs lower heat preservation 20 minutes;4th, 45 DEG C are cooled to, input preservative, arginine, propolis Extract, such as claim 1-3 any one of them skin care compositions, 2000rpm homogenous disperses 1-2 minutes stir evenly;Drop It warms to room temperature, discharges.
CN201810282709.3A 2018-03-31 2018-03-31 A kind of natural ageing-resistant skin care composition and its application Withdrawn CN108186483A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108578296A (en) * 2018-06-27 2018-09-28 广州市科能化妆品科研有限公司 A kind of delay aging drug extraction composition and its preparation and the application in cosmetics
CN109568506A (en) * 2018-12-28 2019-04-05 威海百合生物技术股份有限公司 A kind of U.S. face anti-apolexis composition and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108578296A (en) * 2018-06-27 2018-09-28 广州市科能化妆品科研有限公司 A kind of delay aging drug extraction composition and its preparation and the application in cosmetics
CN109568506A (en) * 2018-12-28 2019-04-05 威海百合生物技术股份有限公司 A kind of U.S. face anti-apolexis composition and preparation method thereof

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Application publication date: 20180622