CN108186398B - Aerosol composition capable of cooling and refreshing and aerosol product - Google Patents

Abstract

The invention belongs to the field of cosmetics, and particularly relates to a cooling aerosol composition and an aerosol product, which comprise the following raw materials in parts by mass: 50-90% of propellant, 3-40% of water and 0.1-10% of ethanol. The invention also discloses an aerosol product containing the composition. The aerosol composition disclosed by the invention has the advantages of uniform mixing of three phases, good stability, capability of rapidly cooling an aerosol product, capability of being used for personal care and convenience in carrying and use.

Description

Aerosol composition capable of cooling and refreshing and aerosol product

Technical Field

The invention belongs to the field of cosmetics, and particularly relates to a cooling aerosol composition and an aerosol product.

Background

The prior art contains preparations for medical treatment for rapidly reducing the temperature of human skin, which can be carried by carriers of various forms so as to be conveniently used for reducing the temperature of human skin and relieving the pain of a patient with fever. For example, chinese patent application CN205181579U discloses an antipyretic cooling patch, which comprises a backing layer, a gel layer and an isolation protective layer, wherein the gel layer is made of cataplasm as a base material, and medical alcohol and menthol are added. These products are inconvenient to use and are limited to medical cooling. In daily life, the people need to cool down in many cases, for example, in hot seasons and in hot days, people want to cool down by using ice, so that the purpose of personal care is achieved. However, ice is difficult to obtain and carry in hot outdoor areas. In order to improve the quality of life, many people want to carry out personal care by reducing the skin temperature freely in summer, so that a product which is convenient to carry and use and can quickly reduce the skin temperature of a human body is needed.

Chinese patent application CN103083197A discloses a human body cooling agent, which comprises the following components by volume percent: 0.5-5% of d-limonene, 20-50% of ethanol, 45-79.5% of water, and the ethanol is medical grade ethanol; a human cooling spray, comprising: a human body cooling agent and a spray bottle, wherein the spray bottle consists of a spray can, an aerosol valve, a spray head, a suction pipe and a cover. The human body cooling spray has the fresh fragrance of sweet orange, good cooling effect and low cost. The invention is a spray, the temperature is reduced mainly by ethanol volatilization, the ethanol content is more than 20 percent, the skin is easy to be stimulated, simultaneously, the ethanol can absorb a large amount of moisture in the epidermis, and the invention has no moisture-preserving skin-care components and is easy to cause the skin dryness.

Chinese patent application CN102670421A discloses a cooling aerosol composition for personal care, comprising a propellant, water and ethanol; also comprises excipient, emollient, humectant, menthol and cyclic siloxane, and also discloses an aerosol product containing the composition. The invention can be cooled rapidly, can be used for personal care, and the aerosol product is convenient to carry and use, but the invention is a mixture of solid, liquid and gas, and the problems of solid silicon dioxide sedimentation, menthol precipitation and the like can occur.

In view of the above problems, there is a need for a cooling aerosol composition and an aerosol product, which can reduce the amount of ethanol, reduce the irritation to skin, moisturize and protect skin, have excellent stability, and uniformly distribute the content.

Disclosure of Invention

The invention aims to provide a cool and refreshing cooling aerosol composition and an aerosol product. The aerosol composition provided by the invention is three-phase mixed, the components are uniformly distributed, the stability is good, the ethanol content is low, the irritation is small, and the moisturizing and skin moistening functions are realized; the aerosol product provided by the invention is convenient to carry and use, and can be rapidly cooled.

In order to achieve the purpose, the invention adopts the following technical scheme:

the cooling aerosol composition comprises the following raw materials in parts by mass: 50-90% of propellant, 3-40% of water and 0.1-10% of ethanol.

Further, the propellant is selected from at least one of dimethyl ether, liquefied petroleum gas, HFC-152a and HFC-134 a.

Still further, the aerosol composition also comprises an excipient, and the mass fraction of the excipient is 0.3-12%.

Further, the excipient consists of hydroxyethyl cellulose, sodium caseinate and modified nano silicon dioxide in a weight ratio of (1-5) to (1-10).

Furthermore, the preparation method of the modified nano silicon dioxide comprises the following steps:

putting the nano silicon dioxide into ethanol, and performing ultrasonic dispersion for 30min to obtain a system A; and (3) placing the system A in a reaction kettle, setting the temperature at 200 ℃ and the pressure at 15-30MPa, and reacting for 2-6h to obtain the modified nano silicon dioxide.

Further, the aerosol composition also comprises an emollient, and the mass fraction of the emollient is 0.01-11%; the emollient is selected from one or more of isopropyl myristate, glycerin and butylene glycol.

Still further, the aerosol composition also comprises menthol, and the mass fraction of the menthol is 0.01-0.5%.

Further, the aerosol composition also comprises cyclic siloxane, and the mass fraction of the cyclic siloxane is 0.1-6%.

In addition, the aerosol product with cooling function comprises the cooling aerosol composition and an aerosol can for canning the composition, wherein the aerosol can is provided with a nozzle.

Further, the preparation method of the aerosol product comprises the following steps:

s1, respectively preparing the oil phase and the water phase, and then mixing, stirring and homogenizing the oil phase and the water phase to form emulsion;

s2, filling the emulsion obtained in the step S1 into an aerosol can, filling a valve, sealing, filling propellant, carrying out water bath, filling a nozzle, filling an outer cover, and boxing.

Silica is a solid and is likely to settle in a mixture of an oil phase and an aqueous phase, which affects the stability of the composition. After the nano silicon dioxide with small particle size and large specific surface area is modified by ethanol, the surface energy of the particles is reduced, the particles have lipophilicity, more active substances can be loaded in an oil phase, the particles can be sprayed out together with a propellant, but the particles are small in particle size, easy to agglomerate, difficult to disperse in a mixture and capable of generating precipitates after being placed for a long time.

The sodium caseinate is a food additive, can make the ice cream-shaped composition formed after being sprayed out soft and fine, and can be tightly attached to skin or surface of article, at the same time, the applicant surprisingly found that the sodium caseinate can reduce agglomeration of modified nano silicon dioxide, and make it tend to disperse and stable state in the mixture. Experiments prove that after the aerosol is stored at the temperature of 50 +/-2 ℃ for 8 weeks, the odor, the appearance and the phase state of the aerosol are kept in good states, and the stability is good. Without the addition of sodium caseinate, a small amount of precipitate appeared at week 4 when stored under the same conditions. The sodium caseinate can stabilize and disperse the modified nano-silica, ensure that the menthol loaded on the sodium caseinate is not separated out, keep the fragrance and stabilize the content. Hydroxyethyl cellulose is a water-soluble emulsifier, thickener and stabilizer, has high water retention capacity and good flow regulation, and can uniformly mix components to form a stable suspension mixture.

The invention has the following advantages:

(1) the invention has the greatest characteristic that the ethanol content is reduced by more than 50 percent compared with the prior spray, the invention has small irritation to human body, and all components in the system can be uniformly mixed, the stability is high,

(2) the invention sprays the content on the surface of the body for cooling and moisturizing, and can also spray the content on the surface of the body (such as a towel or a paper towel) to freeze the water in the content to form an ice cream shape, so that the ice-containing towel for cooling can be obtained at any time and any place, and is easy to carry and convenient to use.

Detailed Description

The present invention will be described in further detail with reference to the following examples. It should not be understood that the scope of the above-described subject matter of the present invention is limited to the following examples.

HFC-152a is 1, 1-difluoroethane, HFC-134a is 1,1,1, 2-tetrafluoroethane, all purchased from Fuzhou Hao chemical new materials Co.Ltd of the three Aids; the other components are known to those skilled in the art, and the names of the components are academic convention.

The present invention will be described in detail with reference to examples.

Preparing modified nano silicon dioxide: putting the nano silicon dioxide into ethanol, and performing ultrasonic dispersion for 30min to obtain a system A; and (3) placing the system A in a reaction kettle, setting the temperature to be 250 ℃, the pressure to be 22MPa, and reacting for 4 hours to obtain the modified nano silicon dioxide.

Example 1 Aerosol composition and product with cooling and refreshing effects

Table 1 example 1 components and their mass fractions

Component name	Mass fraction (%, w/w)
		Water (W)	6.00
Ethanol	1.00
		Modified nano silicon dioxide	0.80
Hydroxyethyl cellulose	0.60
		Sodium caseinate	0.60
Butanediol	2.50
		Menthol crystal	0.15
Cyclic siloxanes	0.30
		Liquefied petroleum gas	88.05

The preparation method comprises the following steps:

s1, dissolving hydroxyethyl cellulose, butanediol and sodium caseinate in water to prepare a mixture A; dissolving and dispersing the modified nano silicon dioxide, menthol and cyclic siloxane in ethanol to prepare a mixture B; mixing A and B, stirring, and homogenizing to obtain emulsion;

s2, filling the emulsion into an aerosol can, filling a valve, sealing, filling propellant, carrying out water bath, filling a nozzle, filling an outer cover and boxing.

Example 2 Aerosol composition and product for cooling and refreshing

Table 2 example 2 components and their mass fractions

Component name	Mass fraction (%, w/w)
		Water (W)	14.00
Ethanol	5.00
		Modified nano silicon dioxide	2.00
Hydroxyethyl cellulose	0.20
		Sodium caseinate	0.80
Myristic acid isopropyl ester	0.30
		Glycerol	5.00
Menthol crystal	0.15
		Dimethyl ether	72.55

The preparation method comprises the following steps:

s1, dissolving hydroxyethyl cellulose and sodium caseinate in water to prepare a mixture A; dissolving and dispersing modified nano silicon dioxide, isopropyl myristate, glycerol and menthol in ethanol to prepare a mixture B; mixing A and B, stirring, and homogenizing to obtain emulsion;

s2, filling the emulsion into an aerosol can, filling a valve, sealing, filling propellant, carrying out water bath, filling a nozzle, filling an outer cover and boxing.

Example 3 Aerosol composition and product with cooling and refreshing effects

Table 3 example 3 components and their mass fractions

Component name	Mass fraction (%, w/w)
		Water (W)	26.00
Ethanol	8.00
		Hydroxyethyl cellulose	1.50
Modified nano silicon dioxide	1.50
		Sodium caseinate	0.50
Myristic acid isopropyl ester	0.50
		Glycerol	1.00
Butanediol	1.00
		Menthol crystal	0.15
Cyclic siloxanes	3.00
		HFC-152a	56.85

The preparation method comprises the following steps:

s1, dissolving hydroxyethyl cellulose, butanediol and sodium caseinate in water to prepare a mixture A; dissolving and dispersing modified nano silicon dioxide, isopropyl myristate, glycerol, menthol and cyclic siloxane in ethanol to prepare a mixture B; mixing A and B, stirring, and homogenizing to obtain emulsion;

s2, filling the emulsion into an aerosol can, filling a valve, sealing, filling propellant, carrying out water bath, filling a nozzle, filling an outer cover and boxing.

Comparative example 1 Aerosol composition for cooling and refreshing and Aerosol product

Comparative example 1 differs from example 3 in that comparative example 1 replaces sodium caseinate with sorbitan laurate and the remaining operations and parameters refer to example 3.

Comparative example 2 Aerosol composition for cooling and refreshing and Aerosol product

Comparative example 2 differs from example 3 in that comparative example 2 does not add sodium caseinate, the amount of excipient is increased to the same amount as in example 3, and the rest of the procedure and parameters are referred to in example 3.

Comparative example 3 Aerosol composition for cooling and refreshing and Aerosol product

Comparative example 3 is different from example 3 in that comparative example 3 changes modified nano silica to silica, and the rest of the operation and parameters refer to example 3.

Test example 1 Aerosol product stability test

1. Test subjects: the aerosol formulations prepared in example 3 and comparative examples 1-3.

2. The test method comprises the following steps:

the stability of the aerosol content is tested according to GB/T14449 and 2008 & ltAerosol product test method & gt, and the test content mainly comprises smell, appearance and phase state.

3. And (3) testing results: the test results are shown in Table 4.

TABLE 4 Aerosol 50. + -. 2 ℃ storage test results

As can be seen from Table 4:

(1) example 3 after 8 weeks of storage at 50 + -2 deg.C, the odor, appearance and phase remained good with good stability.

(2) Comparative example 1 (replacement of sodium caseinate by sorbitan laurate) the aerosol prepared showed oil-water separation at week 6, while the sprayed composition was smoothie, indicating that sodium caseinate is more suitable for use in the aerosol system of the invention than sorbitan laurate.

(3) The aerosol formulation prepared in comparative example 2 (no sodium caseinate) stored under the same conditions, with a fine gritty texture at week 0, a gritty and then grainy feel at week 4, with precipitation starting and increasing, stratification of the oil phase at week 6, more precipitation occurring, and a lighter fragrance, indicating that the presence of sodium caseinate can improve the stability of the aerosol formulation.

(4) Comparative example 3 (replacement of modified nanosilica for silica) the aerosol prepared in accordance with comparative example 3 was stored under the same conditions for 8 weeks, and a small amount of precipitation occurred in week 2, while the sprayed composition had a fine sandy texture and a lighter fragrance, probably due to easy agglomeration among silica particles to form precipitates, and the fragrance gradually decreased with the precipitation of the carrier.

Test example 2 test of Cooling Effect

1. Test subjects: examples 1-3 aerosols were prepared.

2. The test method comprises the following steps:

A. under standard test conditions, a 500mL triangular flask with a plug is used (a thermometer is placed in a rubber plug hole), the thermometer is placed into the triangular flask to be kept at a constant temperature of 30 ℃, then a sample is sprayed by 10g by aiming at the bottom of the triangular flask, then the bottle plug is covered, the thermometer is inserted into the bottom of the triangular flask, after 2min, the thermometer is read and recorded, and finally the temperature drop range of the thermometer is observed.

B. A stack of paper towels (approximately 1mm thick) was placed into the bottom of the stoppered triangular flask and the process repeated.

3. And (3) testing results:

A. a thin crystalline layer appeared at the bottom of the bottle, and examples 1-3 all reduced the temperature of the bottom surface of the bottle by more than 25 ℃.

B. The paper towel had a slightly hard surface and was felt to have ice on the paper towel, which was dry and cold to the touch. Examples 1-3 the towel surface temperature was reduced by more than 25 c.

The above experimental results show that the aerosol provided by the invention has excellent cooling effect.

The foregoing embodiments are merely illustrative of the principles and utilities of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or change the above-mentioned embodiments without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.

Claims (2)

1. The cooling aerosol composition is characterized by comprising the following raw materials in parts by mass: propellant 50-90%, water 3-40% and ethanol 0.1-10%; the aerosol composition also comprises an excipient, wherein the mass fraction of the excipient is 0.3-12%; the excipient consists of hydroxyethyl cellulose, sodium caseinate and modified nano silicon dioxide in a weight ratio of (1-5) to (1-10); the preparation method of the modified nano silicon dioxide comprises the following steps:

putting the nano silicon dioxide into ethanol, and performing ultrasonic dispersion for 30min to obtain a system A; placing the system A in a reaction kettle, setting the temperature at 200 ℃ and the pressure at 15-30MPa, and reacting for 2-6h to obtain modified nano silicon dioxide; the aerosol composition also comprises an emollient, and the mass fraction of the emollient is 0.01-11%; the emollient is selected from one or more of isopropyl myristate, glycerin and butylene glycol; the aerosol composition also comprises menthol, and the mass fraction of the menthol is 0.01-0.5%; the aerosol composition also comprises cyclic siloxane, and the mass fraction of the cyclic siloxane is 0.1-6%; the propellant is at least one selected from dimethyl ether, liquefied petroleum gas, HFC-152a and HFC-134 a.

2. An aerosol product for cooling comprising the cooling aerosol composition of claim 1 and an aerosol canister for containing the composition, the aerosol canister having a nozzle;

the preparation method of the aerosol product comprises the following steps:

s1, respectively preparing the oil phase and the water phase, and then mixing, stirring and homogenizing the oil phase and the water phase to form emulsion;

s2, filling the emulsion obtained in the step S1 into an aerosol can, filling a valve, sealing, filling propellant, carrying out water bath, filling a nozzle, filling an outer cover, and boxing.