CN108159119A - A kind of storage method of the root of fangji - Google Patents
A kind of storage method of the root of fangji Download PDFInfo
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- CN108159119A CN108159119A CN201810122626.8A CN201810122626A CN108159119A CN 108159119 A CN108159119 A CN 108159119A CN 201810122626 A CN201810122626 A CN 201810122626A CN 108159119 A CN108159119 A CN 108159119A
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- Prior art keywords
- fangji
- root
- warehouse
- pile
- portions
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- 238000003860 storage Methods 0.000 title claims abstract description 55
- 238000000034 method Methods 0.000 title claims abstract description 29
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 50
- 244000045947 parasite Species 0.000 claims abstract description 32
- 230000001954 sterilising effect Effects 0.000 claims abstract description 28
- 239000000463 material Substances 0.000 claims abstract description 22
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 22
- 238000001035 drying Methods 0.000 claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 12
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims abstract description 11
- 238000012856 packing Methods 0.000 claims abstract description 6
- 241000251468 Actinopterygii Species 0.000 claims description 7
- 240000004510 Agastache rugosa Species 0.000 claims description 7
- 244000061520 Angelica archangelica Species 0.000 claims description 7
- 235000007516 Chrysanthemum Nutrition 0.000 claims description 7
- 241000735527 Eupatorium Species 0.000 claims description 7
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 7
- 244000246386 Mentha pulegium Species 0.000 claims description 7
- 235000016257 Mentha pulegium Nutrition 0.000 claims description 7
- 235000004357 Mentha x piperita Nutrition 0.000 claims description 7
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- 235000001050 hortel pimenta Nutrition 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 230000003442 weekly effect Effects 0.000 claims description 7
- 150000001637 borneol derivatives Chemical class 0.000 claims description 6
- 239000012535 impurity Substances 0.000 claims description 5
- 238000000643 oven drying Methods 0.000 claims description 5
- 239000002689 soil Substances 0.000 claims description 5
- 240000005250 Chrysanthemum indicum Species 0.000 claims 1
- 241000607479 Yersinia pestis Species 0.000 abstract description 28
- 102000002322 Egg Proteins Human genes 0.000 abstract description 10
- 108010000912 Egg Proteins Proteins 0.000 abstract description 10
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- 230000009286 beneficial effect Effects 0.000 abstract description 3
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- 230000001557 mycostatic effect Effects 0.000 abstract description 3
- 239000004480 active ingredient Substances 0.000 abstract description 2
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- 230000000857 drug effect Effects 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 23
- 241000238631 Hexapoda Species 0.000 description 22
- 230000006378 damage Effects 0.000 description 9
- 241000723353 Chrysanthemum Species 0.000 description 6
- 229910052957 realgar Inorganic materials 0.000 description 5
- WVTKBKWTSCPRNU-KYJUHHDHSA-N (+)-Tetrandrine Chemical compound C([C@H]1C=2C=C(C(=CC=2CCN1C)OC)O1)C(C=C2)=CC=C2OC(=C2)C(OC)=CC=C2C[C@@H]2N(C)CCC3=CC(OC)=C(OC)C1=C23 WVTKBKWTSCPRNU-KYJUHHDHSA-N 0.000 description 4
- MKYBYDHXWVHEJW-UHFFFAOYSA-N N-[1-oxo-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propan-2-yl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(C(C)NC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 MKYBYDHXWVHEJW-UHFFFAOYSA-N 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 3
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
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- IIQSJHUEZBTSAT-VMPREFPWSA-N fangchinoline Chemical compound C([C@H]1C=2C=C(C(=CC=2CCN1C)OC)O1)C(C=C2)=CC=C2OC(=C2)C(OC)=CC=C2C[C@@H]2N(C)CCC3=CC(OC)=C(O)C1=C23 IIQSJHUEZBTSAT-VMPREFPWSA-N 0.000 description 2
- IIQSJHUEZBTSAT-UHFFFAOYSA-N fangchinoline Natural products O1C(C(=CC=2CCN3C)OC)=CC=2C3CC(C=C2)=CC=C2OC(=C2)C(OC)=CC=C2CC2N(C)CCC3=CC(OC)=C(O)C1=C23 IIQSJHUEZBTSAT-UHFFFAOYSA-N 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- WVTKBKWTSCPRNU-UHFFFAOYSA-N rac-Tetrandrin Natural products O1C(C(=CC=2CCN3C)OC)=CC=2C3CC(C=C2)=CC=C2OC(=C2)C(OC)=CC=C2CC2N(C)CCC3=CC(OC)=C(OC)C1=C23 WVTKBKWTSCPRNU-UHFFFAOYSA-N 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 1
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 description 1
- XQINTCORIZHGFD-UHFFFAOYSA-O 1,2,10-trimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinoline-6-ium-11-ol Chemical compound C1=C(OC)C(OC)=C2C3=C(O)C(OC)=CC=C3CC3[N+](C)(C)CCC1=C23 XQINTCORIZHGFD-UHFFFAOYSA-O 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000006479 Cyme Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241001369613 Stephania tetrandra Species 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
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- 238000002845 discoloration Methods 0.000 description 1
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- 230000035619 diuresis Effects 0.000 description 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 230000035784 germination Effects 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
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- 238000004519 manufacturing process Methods 0.000 description 1
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- 229940023569 palmate Drugs 0.000 description 1
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- 235000019698 starch Nutrition 0.000 description 1
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- 210000003462 vein Anatomy 0.000 description 1
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
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- A—HUMAN NECESSITIES
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- A01N31/06—Oxygen or sulfur directly attached to a cycloaliphatic ring system
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
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- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
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- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
- A61L2/208—Hydrogen peroxide
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
- B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
- B65D81/266—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators for absorbing gases, e.g. oxygen absorbers or desiccants
- B65D81/268—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators for absorbing gases, e.g. oxygen absorbers or desiccants the absorber being enclosed in a small pack, e.g. bag, included in the package
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G1/00—Storing articles, individually or in orderly arrangement, in warehouses or magazines
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- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
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- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/25—Rooms in buildings, passenger compartments
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
- Pest Control & Pesticides (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Mechanical Engineering (AREA)
- Food Science & Technology (AREA)
- Alternative & Traditional Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
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Abstract
The invention discloses a kind of storage method of the root of fangji, including going to clean, being sliced, drying, packing, sterilizing, storing；The present invention kills mould and worm's ovum that medicinal material may carry in itself by ethylene oxide sterilizing；It is fumigated, can be carried out disinfection to warehouse by hydrogen peroxide；Periodically using ultra violet lamp, and the humiture environment in warehouse is strictly controlled, these aggregate measures can press down mycostatic growth, the root of fangji is effectively prevent to go mouldy in storage well；By the Chinese medicine expelling parasite packet of the safety non-pollution of original creation, can effective pest repelling, prevent the root of fangji from damaging by worms in storage；Opposite low temperature drying environment is also beneficial to the reservation of root of fangji active ingredient, maximum holding drug effect in warehouse.
Description
Technical field
The present invention relates to Chinese medicine storage technology fields, and in particular to a kind of storage method of the root of fangji.
Background technology
The root of fangji is the dry root of menispermaceous plants Fourstamen Stephania Root Stephania tetrandra S.Moore.Chondodendron is for many years
Raw fallen leaves winding liana, root is cylindrical, and stem is very thin, there is the vertical stripe slightly distorted, and leaf alternate, wide triangular shape is avette, long 3.5-6.5
Centimetre, 5-7 centimetres wide, apex is blunt, has a small prominent point, base portion section shape or slightly in heart, full edge, above green, below celadon extremely
White powder, two sides is by pubescence, palmate vein 5；Petiole peltate life, 5-6 centimetres long.Spend small, unisexuality, monoecism；Male flower
Sequence is cymose inflorescence, is arranged in total shape, male flower sepal 4, petal 4, yellow green, stamen 4, filigree joint into column, on
Portion's plate-like, anther life thereon；Female flower integrates the cyme of cripetura, and sepal, petal and male flower are same, and carpel 1, style 3 is split.Core
Fruit is spherical, red when ripe.The month at florescence 5-6, the fruiting period 7-9 months.Summer at florescence, fruiting period autumn.Root of fangji main product is in Jiangxi, Zhejiang, peace
The provinces such as emblem, Fujian, Taiwan, Hunan are born in the shrubbery on village side, wilderness, roadside etc., are used as medicine with fleshy taproot, claim Fourstamen Stephania Root,
It is bitterly, cold in nature, function dispelling wind and eliminating dampness, inducing diuresis for treating strangurtia.Containing a variety of alkaloids, wherein main component tetrandrine is to treating rheumatism
Arthritis and vascular hypertension are effective.
The preservation process of Chinese medicine, be primarily present damage by worms, go mouldy, bellding, discoloration, scent dissipation, weathering, deliquescence, distillation,
The problems such as thawing, and the root of fangji belongs to ratio of rhizome medicinal material, in storage, easily damages by worms and goes mouldy.
The harm damaged by worms and gone mouldy：Pest by medicinal material moth erosion into cavity, when serious inside eat hollow, reduce medicinal material weight,
Have and lost compared with ingredient, reduce or lose therapeutic effect；The pollution Chinese medicines such as pest excrement, secretion, worm corpse, worm skin, worm bits, clothes
Harm is brought to health with rear；Pest is the medium to carry disease germs, be pathogenic bacteria, fungus growth breeding nutriment, cause
General character endangers, and the medicinal material damaged by worms is unfavorable to disease treatment, and can bring harm；After medicinal material is damaged by worms, loss, band can be increased
Carry out certain economic loss；The Chinese medicine easily damaged by worms（General starch-containing, protein, fat oil, carbohydrate）, while be also the training of mould
Base is supported, is easily gone mouldy, reduces medical value.
The reason of root of fangji easily damages by worms, goes mouldy：It is contaminated in pick and process, fails to kill worm's ovum completely when dry, once ring
Border condition is suitable, and worm's ovum can hatch adult；The warehouse of storage is interior in itself worm's ovum, in environmental condition suitable in the case of, i.e.,
Insect pest can occur；Containing a large amount of mycotics spore in air, medicinal material surface is scattered in, when mould encounters suitable epidemic disaster, that is, is sprouted
Bacterium germination silk, and ferment is secreted, corrode medicinal material organization internal.
Root of fangji medicinal material harvests generally at the beginning of the autumn, immediately into storage phase, and at a time when this root of fangji producing region high temperature and humidity season
Section, since conventional storage method storage ambient is poorly sealed, extraneous humid air is easily accessible, and storage ambient humidity is caused to increase,
Mould and worm's ovum are easily grown；In addition worm's ovum and mould do not have or fail to kill completely in storage ambient, medicinal material appearance also carries
There is worm's ovum mould to enter storeroom, the storage time for eventually leading to the root of fangji is short, therefore improves the storage method of the upper root of fangji of production, with
The storage time for extending the root of fangji is very necessary.
Invention content
In view of the deficiencies of the prior art, the purpose of the present invention is to provide a kind of storage method of the root of fangji, the storage methods
The root of fangji can be avoided to damage by worms and go mouldy, significantly extend the storage time of the root of fangji.
To achieve the above object, the present invention provides following technical solution：
A kind of storage method of the root of fangji, includes the following steps：
A, it cleans：The root of fangji with flowing water is rinsed, removes the soil and impurity on surface；
B, it is sliced：The reciprocating automatic medicine cutter of the cleaned root of fangji is sliced, slice thickness 3-8mm；
C, drying：By the root of fangji oven drying of slice to moisture 8-10%；
D, it packs：The dried root of fangji is packed into gunnysack, 50kg/ bags of packing specification；
E, it sterilizes：Sterilization treatment is carried out to the packaged root of fangji；
F, it stores：
（1）It fumigates in warehouse：Warehouse is fumigated using hydrogen peroxide, the dosage of hydrogen peroxide is 10-50ml/m3, it is small to fumigate 12-24
The root of fangji of sterilizing is put in storage by Shi Hou；
The mass concentration of the hydrogen peroxide is 1.5-3%；
（2）Warehouse epidemic disaster control：MW temperature is controlled at 4-10 DEG C, and humid control is in 30-50%；
（3）Cargo piles up rule：50kg/ bags of the root of fangji is neatly deposited on material frame, every 10 bags pile one and chop, pile and ground
Spacing ＞ 10cm, spacing ＞ 50cm, the spacing ＞ 80cm between pile and pile of pile and metope, place one on four angles per pile
A expelling parasite packet；
Described every bag of weight 100g of expelling parasite packet, is packed with gauze；
The expelling parasite includes the component of following parts by weight：50-80 portions of Dalmatian chrysanthemums, 40-50 portions of fish pelargoniums, 30-60 portions of folium artemisiae argyis,
40-70 portions of peppermints, the 10-50 parts of roots of Dahurain angelica, 20-30 portions of wrinkled giant hyssops, 15-30 portions of eupatoriums, 1-5 parts of borneols, 0.5-0.9 portions of realgars；
（4）Inspect periodically item：Expelling parasite packet is quarterly replaced once；Ultraviolet lamp irradiates weekly once, and each irradiation time 8 is small
When.
Further, the drying steps described in step C were specifically divided into for three stages：The root of fangji being sliced is put by the first stage
Continuous drier, 65-70 DEG C of set temperature, dry 3-5h take out, and stack to warehouse, the indoor temperature in warehouse is controlled 20 ± 5
DEG C, relative humidity control is stacked 5-7 days 60 ± 5%；The root of fangji of first stage is put into continuous drier by second stage, if
Put 55-60 DEG C of temperature, dry 10-15h takes out, and stacks to warehouse, and the indoor temperature control in warehouse is at 25 ± 5 DEG C, relative humidity
Control is stacked 3-4 days 55 ± 5%；The root of fangji of second stage is put into continuous drier, set temperature 35-40 by the phase III
DEG C, it is dry to moisture 8-10%.
Further, the sterilization steps described in step E sterilize for Low-temperature epoxy ethane, sterilization time 12-24 hours.
Compared with prior art, beneficial effects of the present invention：1st, by ethylene oxide sterilizing, killing medicinal material may take in itself
The mould of band and worm's ovum；It is fumigated, can be carried out disinfection to warehouse by hydrogen peroxide；Periodically using ultra violet lamp, and strictly control
The humiture environment in warehouse, these aggregate measures can press down mycostatic growth, effectively prevent the root of fangji in storage well
It goes mouldy；2nd, by the Chinese medicine expelling parasite packet of the safety non-pollution of original creation, can effective pest repelling, prevent the root of fangji in storage
It is middle to damage by worms；3rd, low temperature drying environment opposite in warehouse is also beneficial to the reservation of root of fangji active ingredient, maximum holding medicine
Effect, and it is divided into three phases in the drying process, and have the process for piling up sweating, it can in the drying process to the greatest extent
Remove the root of fangji in Free water and with reference to water, this effectively prevents backwater phenomenon of the root of fangji in later stage storage, ensure that
The quality of product.
Specific embodiment
Embodiment 1：
A kind of storage method of the root of fangji, includes the following steps：
A, it cleans：The root of fangji with flowing water is rinsed, removes the soil and impurity on surface；
B, it is sliced：The reciprocating automatic medicine cutter of the cleaned root of fangji is sliced, slice thickness 3mm；
C, drying：By the root of fangji oven drying of slice to moisture 8%；
D, it packs：The dried root of fangji is packed into gunnysack, 50kg/ bags of packing specification；
E, it sterilizes：Sterilization treatment is carried out to the packaged root of fangji；
F, it stores：
（1）It fumigates in warehouse：Warehouse is fumigated using hydrogen peroxide, the dosage of hydrogen peroxide is 10ml/m3, after fumigating 12 hours,
The root of fangji of sterilizing is put in storage；
The mass concentration of the hydrogen peroxide is 1.5%；
（2）Warehouse epidemic disaster control：MW temperature is controlled at 4 DEG C, and humid control is 30%；
（3）Cargo piles up rule：50kg/ bags of the root of fangji is neatly deposited on material frame, every 10 bags pile one and chop, pile and ground
Spacing 15cm, spacing 60cm, the spacing 85cm between pile and pile of pile and metope, place an expelling parasite on four angles per pile
Packet；
Described every bag of weight 100g of expelling parasite packet, is packed with gauze；
The expelling parasite includes the component of following parts by weight：50 portions of Dalmatian chrysanthemums, 40 portions of fish pelargoniums, 30 portions of folium artemisiae argyis, 40 portions of peppermints,
10 parts of roots of Dahurain angelica, 20 portions of wrinkled giant hyssops, 15 portions of eupatoriums, 1 part of borneol, 0.5 portion of realgar；
（4）Inspect periodically item：Expelling parasite packet is quarterly replaced once；Ultraviolet lamp irradiates weekly once, and each irradiation time 8 is small
When.
Further, the drying steps described in step C were specifically divided into for three stages：The root of fangji being sliced is put by the first stage
Continuous drier, 65 DEG C of set temperature, dry 3h take out, and stack to warehouse, the indoor temperature in warehouse is controlled at 20 DEG C, relatively
Humid control is stacked 5 days 55%；The root of fangji of first stage is put into continuous drier by second stage, and 55 DEG C of set temperature is done
Dry 10h takes out, and stacks to warehouse, and at 20 DEG C, relative humidity control is stacked 3 days 50% for the indoor temperature control in warehouse；Third
The root of fangji of second stage is put into continuous drier by the stage, and 35 DEG C of set temperature is dry to moisture 8%.
Further, the sterilization steps described in step E sterilize for Low-temperature epoxy ethane, sterilization time 12 hours.
Embodiment 2：
A kind of storage method of the root of fangji, includes the following steps：
A, it cleans：The root of fangji with flowing water is rinsed, removes the soil and impurity on surface；
B, it is sliced：The reciprocating automatic medicine cutter of the cleaned root of fangji is sliced, slice thickness 6mm；
C, drying：By the root of fangji oven drying of slice to moisture 9%；
D, it packs：The dried root of fangji is packed into gunnysack, 50kg/ bags of packing specification；
E, it sterilizes：Sterilization treatment is carried out to the packaged root of fangji；
F, it stores：
（1）It fumigates in warehouse：Warehouse is fumigated using hydrogen peroxide, the dosage of hydrogen peroxide is 30ml/m3, after fumigating 18 hours,
The root of fangji of sterilizing is put in storage；
The mass concentration of the hydrogen peroxide is 2%；
（2）Warehouse epidemic disaster control：MW temperature is controlled at 7 DEG C, and humid control is 40%；
（3）Cargo piles up rule：50kg/ bags of the root of fangji is neatly deposited on material frame, every 10 bags pile one and chop, pile and ground
Spacing 20cm, spacing 70cm, the spacing 90cm between pile and pile of pile and metope, place an expelling parasite on four angles per pile
Packet；
Described every bag of weight 100g of expelling parasite packet, is packed with gauze；
The expelling parasite includes the component of following parts by weight：60 portions of Dalmatian chrysanthemums, 45 portions of fish pelargoniums, 45 portions of folium artemisiae argyis, 55 portions of peppermints,
30 parts of roots of Dahurain angelica, 25 portions of wrinkled giant hyssops, 25 portions of eupatoriums, 3 parts of borneols, 0.7 portion of realgar；
（4）Inspect periodically item：Expelling parasite packet is quarterly replaced once；Ultraviolet lamp irradiates weekly once, and each irradiation time 8 is small
When.
Further, the drying steps described in step C were specifically divided into for three stages：The root of fangji being sliced is put by the first stage
Continuous drier, 68 DEG C of set temperature, dry 4h take out, and stack to warehouse, the indoor temperature in warehouse is controlled at 20 DEG C, relatively
Humid control is stacked 6 days 60%；The root of fangji of first stage is put into continuous drier by second stage, and 58 DEG C of set temperature is done
Dry 12h takes out, and stacks to warehouse, and at 25 DEG C, relative humidity control is stacked 3 days 55% for the indoor temperature control in warehouse；Third
The root of fangji of second stage is put into continuous drier by the stage, and 37 DEG C of set temperature is dry to moisture 9%.
Further, the sterilization steps described in step E sterilize for Low-temperature epoxy ethane, sterilization time 18 hours.
Embodiment 3：
A kind of storage method of the root of fangji, includes the following steps：
A, it cleans：The root of fangji with flowing water is rinsed, removes the soil and impurity on surface；
B, it is sliced：The reciprocating automatic medicine cutter of the cleaned root of fangji is sliced, slice thickness 8mm；
C, drying：By the root of fangji oven drying of slice to moisture 10%；
D, it packs：The dried root of fangji is packed into gunnysack, 50kg/ bags of packing specification；
E, it sterilizes：Sterilization treatment is carried out to the packaged root of fangji；
F, it stores：
（1）It fumigates in warehouse：Warehouse is fumigated using hydrogen peroxide, the dosage of hydrogen peroxide is 50ml/m3, after fumigating 24 hours,
The root of fangji of sterilizing is put in storage；
The mass concentration of the hydrogen peroxide is 3%；
（2）Warehouse epidemic disaster control：MW temperature is controlled at 10 DEG C, and humid control is 50%；
（3）Cargo piles up rule：50kg/ bags of the root of fangji is neatly deposited on material frame, every 10 bags pile one and chop, pile and ground
Spacing 15cm, spacing 55cm, the spacing 85cm between pile and pile of pile and metope, place an expelling parasite on four angles per pile
Packet；
Described every bag of weight 100g of expelling parasite packet, is packed with gauze；
The expelling parasite includes the component of following parts by weight：80 portions of Dalmatian chrysanthemums, 50 portions of fish pelargoniums, 60 portions of folium artemisiae argyis, 70 portions of peppermints,
50 parts of roots of Dahurain angelica, 30 portions of wrinkled giant hyssops, 30 portions of eupatoriums, 5 parts of borneols, 0.9 portion of realgar；
（4）Inspect periodically item：Expelling parasite packet is quarterly replaced once；Ultraviolet lamp irradiates weekly once, and each irradiation time 8 is small
When.
Further, the drying steps described in step C were specifically divided into for three stages：The root of fangji being sliced is put by the first stage
Continuous drier, 70 DEG C of set temperature, dry 5h take out, and stack to warehouse, the indoor temperature in warehouse is controlled at 25 DEG C, relatively
Humid control is stacked 7 days 65%；The root of fangji of first stage is put into continuous drier by second stage, and 60 DEG C of set temperature is done
Dry 15h takes out, and stacks to warehouse, and at 30 DEG C, relative humidity control is stacked 4 days 60% for the indoor temperature control in warehouse；Third
The root of fangji of second stage is put into continuous drier by the stage, and 40 DEG C of set temperature is dry to moisture 10%.
Further, the sterilization steps described in step E sterilize for Low-temperature epoxy ethane, sterilization time 24 hours.
Comparative example 1：
A kind of storage method of the root of fangji, without the sterilization steps described in step E, remaining is the same as embodiment 1.
Comparative example 2：
A kind of storage method of the root of fangji, step F are changed to：
（1）Warehouse epidemic disaster control：MW temperature is controlled at 7 DEG C, and humid control is 40%；
（2）Cargo piles up rule：50kg/ bags of the root of fangji is neatly deposited on material frame, every 10 bags pile one and chop, pile and ground
Spacing 20cm, spacing 70cm, the spacing 90cm between pile and pile of pile and metope, place an expelling parasite on four angles per pile
Packet；
Described every bag of weight 100g of expelling parasite packet, is packed with gauze；
The expelling parasite includes the component of following parts by weight：60 portions of Dalmatian chrysanthemums, 45 portions of fish pelargoniums, 45 portions of folium artemisiae argyis, 55 portions of peppermints,
30 parts of roots of Dahurain angelica, 25 portions of wrinkled giant hyssops, 25 portions of eupatoriums, 3 parts of borneols, 0.7 portion of realgar；
（3）Inspect periodically item：Expelling parasite packet is quarterly replaced once.Remaining is the same as embodiment 2.
Comparative example 3：
A kind of storage method of the root of fangji, step F are changed to：
（1）It fumigates in warehouse：Warehouse is fumigated using hydrogen peroxide, the dosage of hydrogen peroxide is 50ml/m3, after fumigating 24 hours,
The root of fangji of sterilizing is put in storage；
The mass concentration of the hydrogen peroxide is 3%；
（2）Warehouse epidemic disaster control：MW temperature is controlled at 10 DEG C, and humid control is 50%；
（3）Cargo piles up rule：50kg/ bags of the root of fangji is neatly deposited on material frame, every 10 bags pile one and chop, pile and ground
Spacing 15cm, the spacing 55cm, the spacing 85cm between pile and pile of pile and metope；
（4）Inspect periodically item：Ultraviolet lamp irradiates weekly once, each irradiation time 8 hours.Remaining is the same as embodiment 3.
Comparative example 4：
A kind of storage method of the root of fangji, step F are changed to：
（1）It fumigates in warehouse：Warehouse is fumigated using hydrogen peroxide, the dosage of hydrogen peroxide is 50ml/m3, after fumigating 24 hours,
The root of fangji of sterilizing is put in storage；
The mass concentration of the hydrogen peroxide is 3%；
（2）Warehouse epidemic disaster control：MW temperature is room temperature, and humidity is without control；
（3）Cargo piles up rule：50kg/ bags of the root of fangji is neatly deposited on material frame, every 10 bags pile one and chop, pile and ground
Spacing 15cm, spacing 55cm, the spacing 85cm between pile and pile of pile and metope, place an expelling parasite on four angles per pile
Packet；
Described every bag of weight 100g of expelling parasite packet, is packed with gauze；
The expelling parasite includes the component of following parts by weight：80 portions of Dalmatian chrysanthemums, 50 portions of fish pelargoniums, 60 portions of folium artemisiae argyis, 70 portions of peppermints,
50 parts of roots of Dahurain angelica, 30 portions of wrinkled giant hyssops, 30 portions of eupatoriums, 5 parts of borneols, 0.9 portion of realgar；
（4）Inspect periodically item：Expelling parasite packet is quarterly replaced once；Ultraviolet lamp irradiates weekly once, and each irradiation time 8 is small
When.
Experiment 1：Observe the situation of going mouldy in root of fangji storage.
Observation method：The situation of going mouldy of bag sampling observation embodiment 1-3 and the comparative example 1-4 roots of fangji is opened within every six months, it is mould
Become grading：
Without going mouldy, no mildew is visually observed；
Level-one is gone mouldy, the amount of going mouldy accounting≤20%；
Two level is gone mouldy, the amount of going mouldy accounting 20%-50%；
Three-level is gone mouldy, the amount of going mouldy accounting 50%-80%；
Level Four is gone mouldy, the amount of going mouldy accounting >=80%.
Observation situation is shown in Table one：
| Experimental group | 6 months | 12 months | 18 months | 24 months |
| Embodiment 1 | Nothing is gone mouldy | Nothing is gone mouldy | Nothing is gone mouldy | Nothing is gone mouldy |
| Embodiment 2 | Nothing is gone mouldy | Nothing is gone mouldy | Nothing is gone mouldy | Nothing is gone mouldy |
| Embodiment 3 | Nothing is gone mouldy | Nothing is gone mouldy | Nothing is gone mouldy | Nothing is gone mouldy |
| Comparative example 1 | Nothing is gone mouldy | Level-one is gone mouldy | Two level is gone mouldy | Three-level is gone mouldy |
| Comparative example 2 | Nothing is gone mouldy | Level-one is gone mouldy | Two level is gone mouldy | Three-level is gone mouldy |
| Comparative example 3 | Nothing is gone mouldy | Nothing is gone mouldy | Nothing is gone mouldy | Nothing is gone mouldy |
| Comparative example 4 | Nothing is gone mouldy | Nothing is gone mouldy | Level-one is gone mouldy | Two level is gone mouldy |
Observing data by upper table can obtain to draw a conclusion：1st, embodiment 1-3 and comparative example 3 are killed by ethylene oxide sterilizing
The mould and worm's ovum that the medicinal material that goes out may carry in itself；It is fumigated by hydrogen peroxide, carried out disinfection to warehouse；Periodically shone using ultraviolet lamp
It penetrates, and strictly controls the humiture environment in warehouse, these aggregate measures can press down mycostatic growth, can effectively prevent well
The root of fangji goes mouldy in storage；2nd, comparative example 1 does not have an ethylene oxide sterilisation step, comparative example 2 do not have warehouse fumigate and
Ultraviolet light periodically irradiates, and comparative example 4 does not control the humiture in warehouse, this can result in root of fangji storage
It goes mouldy；It can be seen that root of fangji storage method of the present invention has comparable progress relative to traditional storage method.
Experiment 2：Observe the situation of damaging by worms in root of fangji storage.
Observation method：Open within every six months the situation of damaging by worms of bag sampling observation embodiment 1-3 and the comparative example 1-4 roots of fangji, worm
Eat into grading：
Free from insect pests visually observes free from insect pests；
Level-one is damaged by worms, the amount of damaging by worms accounting≤20%；
Two level is damaged by worms, the amount of damaging by worms accounting 20%-50%；
Three-level is damaged by worms, the amount of damaging by worms accounting 50%-80%；
Level Four is damaged by worms, the amount of damaging by worms accounting >=80%.
Observation situation is shown in Table one：
| Experimental group | 6 months | 12 months | 18 months | 24 months |
| Embodiment 1 | Free from insect pests | Free from insect pests | Free from insect pests | Free from insect pests |
| Embodiment 2 | Free from insect pests | Free from insect pests | Free from insect pests | Free from insect pests |
| Embodiment 3 | Free from insect pests | Free from insect pests | Free from insect pests | Free from insect pests |
| Comparative example 1 | Free from insect pests | Level-one is damaged by worms | Two level is damaged by worms | Three-level is damaged by worms |
| Comparative example 2 | Free from insect pests | Free from insect pests | Level-one is damaged by worms | Two level is damaged by worms |
| Comparative example 3 | Free from insect pests | Level-one is damaged by worms | Two level is damaged by worms | Three-level is damaged by worms |
| Comparative example 4 | Free from insect pests | Free from insect pests | Free from insect pests | Level-one is damaged by worms |
Observing data by upper table can obtain to draw a conclusion：1st, embodiment 1-3 kills medicinal material in itself by ethylene oxide sterilizing
The mould that may be carried and worm's ovum；It is fumigated by hydrogen peroxide, carried out disinfection to warehouse；Expelling parasite packet is placed, and strictly controls warehouse
Humiture environment, these aggregate measures can inhibit the growth of pest, can effectively prevent the root of fangji in storage well
It damages by worms；2nd, comparative example 1 does not have an ethylene oxide sterilisation step, and comparative example 2 does not have warehouse to fumigate periodically to irradiate with ultraviolet light, right
Ratio 3 does not control the humiture in warehouse without placing expelling parasite packet, comparative example 4, this can result in the root of fangji and stored
Phenomenon of damaging by worms in journey；It can be seen that root of fangji storage method of the present invention relative to traditional storage method, have it is comparable into
Step.
Experiment 3:Embodiment 1-3 and comparative example 1-4 samples tetrandrine and fangchinoline total amount measure.Test data
It is shown in Table three.
Table three：
The roots of fangji of comparative example 1-4 storages is can be seen that in the storage phase of 2 years by upper table data, and effective content is from average
1.89% drop to 2 years after average 1.27%, have dropped 32.8%, content is already less than Chinese Pharmacopoeia to containing powder in the root of fangji
The total amount of menispermine and fangchinoline must not be less than 1.6% regulation, that is to say, that medicinal material has failed；And embodiment 1-3
The root of fangji of storage in the storage phase of 2 years, effective content from average 1.89% drop to 2 years after average 1.80%, under
The amplitude very little of drop almost keeps stablizing, it is seen that the superiority of storage method of the present invention.
Claims (3)
1. a kind of storage method of the root of fangji, which is characterized in that include the following steps：
A, it cleans：The root of fangji with flowing water is rinsed, removes the soil and impurity on surface；
B, it is sliced：The reciprocating automatic medicine cutter of the cleaned root of fangji is sliced, slice thickness 3-8mm；
C, drying：By the root of fangji oven drying of slice to moisture 8-10%；
D, it packs：The dried root of fangji is packed into gunnysack, 50kg/ bags of packing specification；
E, it sterilizes：Sterilization treatment is carried out to the packaged root of fangji；
F, it stores：
（1）It fumigates in warehouse：Warehouse is fumigated using hydrogen peroxide, the dosage of hydrogen peroxide is 10-50ml/m3, it is small to fumigate 12-24
The root of fangji of sterilizing is put in storage by Shi Hou；
The mass concentration of the hydrogen peroxide is 1.5-3%；
（2）Warehouse epidemic disaster control：MW temperature is controlled at 4-10 DEG C, and humid control is in 30-50%；
（3）Cargo piles up rule：50kg/ bags of the root of fangji is neatly deposited on material frame, every 10 bags pile one and chop, pile and ground
Spacing ＞ 10cm, spacing ＞ 50cm, the spacing ＞ 80cm between pile and pile of pile and metope, place one on four angles per pile
A expelling parasite packet；
Described every bag of weight 100g of expelling parasite packet, is packed with gauze；
The expelling parasite includes the component of following parts by weight：50-80 portions of Dalmatian chrysanthemums, 40-50 portions of fish pelargoniums, 30-60 portions of folium artemisiae argyis,
40-70 portions of peppermints, the 10-50 parts of roots of Dahurain angelica, 20-30 portions of wrinkled giant hyssops, 15-30 portions of eupatoriums, 1-5 parts of borneols, 0.5-0.9 portions of realgars；
（4）Inspect periodically item：Expelling parasite packet is quarterly replaced once；Ultraviolet lamp irradiates weekly once, and each irradiation time 8 is small
When.
A kind of 2. storage method of root of fangji according to claim 1, which is characterized in that the drying steps tool described in step C
Body was divided into for three stages：The root of fangji being sliced is put into continuous drier by the first stage, and 65-70 DEG C of set temperature dries 3-5h,
It takes out, stacks to warehouse, at 20 ± 5 DEG C, relative humidity control is stacked 5-7 days 60 ± 5% for the indoor temperature control in warehouse；The
The root of fangji of first stage is put into continuous drier, 55-60 DEG C of set temperature by the two-stage, and dry 10-15h takes out, stacks extremely
Warehouse, at 25 ± 5 DEG C, relative humidity control is stacked 3-4 days 55 ± 5% for the indoor temperature control in warehouse；Phase III, by
The root of fangji of two-stage is put into continuous drier, and 35-40 DEG C of set temperature is dry to moisture 8-10%.
3. the storage method of a kind of root of fangji according to claim 1, which is characterized in that the sterilization steps described in step E are
Low-temperature epoxy ethane sterilizes, sterilization time 12-24 hours.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111821327A (en) * | 2020-07-29 | 2020-10-27 | 德生堂(江苏)医药有限责任公司 | Processing and storing method of traditional Chinese medicine raw materials |
| CN114757613A (en) * | 2022-04-06 | 2022-07-15 | 武汉诺兴康医疗科技有限公司 | Intelligent management system for storing finished goods in medical instrument production and sales warehouse |
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2018
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111821327A (en) * | 2020-07-29 | 2020-10-27 | 德生堂(江苏)医药有限责任公司 | Processing and storing method of traditional Chinese medicine raw materials |
| CN114757613A (en) * | 2022-04-06 | 2022-07-15 | 武汉诺兴康医疗科技有限公司 | Intelligent management system for storing finished goods in medical instrument production and sales warehouse |
| CN114757613B (en) * | 2022-04-06 | 2023-06-09 | 杭州康晟健康管理咨询有限公司 | Intelligent management system for finished product storage of medical instrument production and sales warehouse goods |
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| CN108159119B (en) | 2021-07-16 |
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