CN108159082A - A kind of Chinese medicine composition, preparation method and its application - Google Patents

A kind of Chinese medicine composition, preparation method and its application Download PDF

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Publication number
CN108159082A
CN108159082A CN201810202372.0A CN201810202372A CN108159082A CN 108159082 A CN108159082 A CN 108159082A CN 201810202372 A CN201810202372 A CN 201810202372A CN 108159082 A CN108159082 A CN 108159082A
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parts
chinese medicine
medicine composition
pearl
beeswax
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王发芹
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a kind of Chinese medicine composition, including the following components counted in parts by weight:Black 5~20 parts of snake, 5~20 parts of sky dragon, 5~15 parts of pearl powder, 5~20 parts of cuttle bone and silver-colored 3~10 parts of pearl, preferably further include 5~20 parts of beeswax.The Traditional Chinese medicine composition formula science has synergistic effect between each component.The therapeutic modalities such as its chemicotherapy without doctor trained in Western medicine, operation, infusion, almost non-toxic side effect have good oncotherapy and antiviral effect.

Description

A kind of Chinese medicine composition, preparation method and its application
Technical field
The present invention relates to technical field of Chinese medicine, and in particular to a kind of Chinese medicine composition, the preparation method of the composition, with And the application of the composition.
Background technology
At present, cancer has become the main reason for influence quality of life and average life span.Most of cancer patients need The therapeutic modalities such as radiotherapy, chemotherapy, operation, infusion are taken to hospital.Aforesaid way can only play the role of temporary relief, and can be straight The cell tissue of injury human body itself is connect, leads to that sb.'s illness took a turn for the worse, immunity of organisms further declines, and virus directly invades.Although Domestic existing a variety of antitumor or antiviral drugs, but these drugs are typically only capable to temporarily delay viral growth or mitigate Disease symptoms, and have the shortcomings that side effect is big, at high price, pharmacological property is undesirable.
In consideration of it, special propose the present invention.
Invention content
The first object of the present invention is to provide a kind of Chinese medicine composition.
The second object of the present invention is to provide the preparation method of above-mentioned composition.
The third object of the present invention is to provide the application of above-mentioned composition.
To achieve the above object, technical scheme is as follows:
The present invention relates to a kind of Chinese medicine composition, including the following components counted in parts by weight:Black 5~20 parts of snake, sky dragon 5 ~20 parts, 5~15 parts of pearl powder, 5~20 parts of cuttle bone and silver-colored 3~10 parts of pearl.
Preferably, the Chinese medicine composition includes the following components counted in parts by weight:Black 8~12 parts of snake, sky dragon 8~12 Part, 8~10 parts of pearl powder, 8~12 parts of cuttle bone and silver-colored 4~6 parts of pearl.
Preferably, the Chinese medicine composition further includes 5~20 parts of beeswax.
Preferably, the Chinese medicine composition further includes 8~12 parts of beeswax.
Preferably, when the Chinese medicine composition includes beeswax, the crow snake, sky dragon, pearl powder, cuttle bone, silver-colored pearl and The weight ratio of beeswax is 6:6:5:6:6:3.
The invention further relates to the preparation methods of the Chinese medicine composition, include the following steps:
(1) black snake, sky dragon, cuttle bone are fried and smashed;
(2) it by enduring of honey, adds in the powder that step (1) obtains and mixes thoroughly, be eventually adding silver-colored pearl and pearl powder makes pill.
Preferably, the mass ratio of the powder and the honey is (1~1.5):1.
Preferably, when the Chinese medicine composition includes beeswax, preparation method includes the following steps:
(1) black snake, sky dragon, cuttle bone are fried and smashed;
(2) it by enduring of beeswax, adds in the powder that step (1) obtains and mixes thoroughly, be eventually adding silver-colored pearl and pearl powder makes pill.
The invention further relates to the applications of the Chinese medicine composition.
Preferably, the Chinese medicine composition can be used for treatment of cancer and antiviral therapy, and the cancer includes pre-cancer And advanced cancer, the antiviral therapy include the treatment of herpes zoster, carbuncle, furuncle, sore, subcutaneous ulcer.
Beneficial effects of the present invention:Traditional Chinese medicine composition formula science provided by the invention there is collaboration to make between each component With.There is good tumour to control for the therapeutic modalities such as its chemicotherapy without doctor trained in Western medicine, operation, infusion, almost non-toxic side effect Treatment and antiviral effect.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical scheme of the present invention will be carried out below Detailed description.Obviously, described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.Base Embodiment in the present invention, those of ordinary skill in the art are obtained all under the premise of creative work is not made Other embodiment belongs to the range that the present invention is protected.
The Chinese medicine composition of the present invention includes the following components counted in parts by weight:Black 5~20 parts of snake, 5~20 parts of sky dragon, 5~15 parts of pearl powder, 5~20 parts of cuttle bone and silver-colored 3~10 parts of pearl.
Between each ingredient of Chinese medicine composition of the present invention there is synergistic effect, there is good oncotherapy and disease-resistant toxic effect Fruit, almost non-toxic side effect.The effect of specific each ingredient, is as follows:
Black snake also known as zaocys dhumnade remove the entirety of internal organ for Colubridae zaocys dhumnade category animal zaocys dhumnade.It is distributed in China Shaanxi, Gansu, Jiangsu, Anhui, Zhejiang, Jiangxi, Fujian, Taiwan, Henan, Hubei, Hunan, Guangdong, Guangxi, Sichuan, Guizhou.Taste It is sweet, salty, mild-natured, there is the effect of wind-damp dispelling, degrading the channel, arresting convulsion, removing toxic substances.Cure mainly rheumatoid arthritis stubborn, numbness, muscle arteries and veins contraction, Quadriplegia, lockjaw, leprosy, rubella mange.
Sky dragon is alias also known as the house lizard of gecko, and the dried product of internal organ is removed for gecko.Taste is salty, trembles with fear.It is slightly poisonous, there is breath Wind antispastic, dispersing pathogen accumulation, remove obstruction in channels to relieve pain, antispastic wind-dispelling and diverging detumescence the effect of, available for treatment scrofula, neuralgia, Chornic arthritis, lump in breast.
Cuttle bone is the inner casing of black Quarry sections animal needleless crow Quarry or Golden Crow Quarry.Taste is salty, puckery, warm-natured, return liver warp kidney channel, the traditional Chinese medical science It is used as hemostatic.There is relieving haperacidity analgesic, hygroscopic sore, available for treatment radiation injury, tumour etc..
Pearl powder is the bivalves such as Pteriidae animal Pinctada martensii, Unionidae animal hydriopsis cumingii or cristaria plicata The pearl of stimulated formation.It is taken out from animal body, cleaning, drying, fine ground powder processed.It is sweet in flavor, salty, it trembles with fear, converge to heart and liver channels have Calm the nerves arresting convulsion, flat liver improving eyesight, it is clearing heat and detoxicating the effect of.Available for treating insomnia of palpitating with fear, infantile convulsion epilepsy, mesh life cloudiness, sore is not It holds back.
Silver-colored pearl also known as vermilion.Be using mercury, sulphur and potassium hydroxide as raw material, it is heated distillation and manufactured mercuric sulphide (HgS).Acrid flavour, warm-natured, toxic, thoughts of returning home lung channel.With attacking poison, the effect of desinsection, eliminating dampness, eliminating the phlegm.Available for treating ulcer, swell Poison, ulcer, wet sore, mange, accumulation of pathogens in chest, children are interior to be fished.
In one embodiment of the invention, Chinese medicine composition includes the following components counted in parts by weight:Black snake 8~12 Part, 8~12 parts of sky dragon, 8~10 parts of pearl powder, 8~12 parts of cuttle bone and silver-colored 4~6 parts of pearl.
Further, Chinese medicine composition of the invention further includes 5~20 parts of beeswax, preferably 8~12 parts.By beeswax with it is above-mentioned Component is used in compounding, and can increase the oncotherapy for changing composition and antiviral effect, reduces toxic side effect.The ingredient of beeswax and treatment Effect is as follows:
Beeswax also known as beeswax are the wax of the workers bee such as apidae insect apis cerana secretion.It is sweet in flavor, tepor, returns spleen, stomach, Large intestine channel.With removing toxic substances, myogenic, the effect of analgesic therapy.Available for treatment anxious pained, diarrhea purulence blood, sore carbuncle inside fire attack, burst for a long time and does not holds back, Scald.
In one embodiment of the invention, when Chinese medicine composition includes beeswax, black snake, sky dragon, pearl powder, cuttlefish The weight ratio of bone, silver-colored pearl and beeswax is 6:6:5:6:6:3.Inventor is the study found that when composition has above proportioning, tumour Treatment and antiviral effect are best.
Invention further provides the preparation methods of the Chinese medicine composition, include the following steps:
(1) black snake, sky dragon, cuttle bone are fried and smashed;
(2) it by enduring of honey, adds in the powder that step (1) obtains and mixes thoroughly, be eventually adding silver-colored pearl and pearl powder makes pill.
In above process, honey primarily serves the effect of moisturizing, seasoning and adhesive.Specific method for refining is by honey First boiling is endured with high heat, then endured slowly with slow boiling, fire is received when honey yellowing foam.Then by medicinal powder and honey with (1~1.5):1 Mass ratio mixes, and pill finally is made with hand or machine.
In one embodiment of the invention, when the Chinese medicine composition includes beeswax, preparation method includes following step Suddenly:
(1) black snake, sky dragon, cuttle bone are fried and smashed;
(2) it by enduring of beeswax, adds in the powder that step (1) obtains and mixes thoroughly, be eventually adding silver-colored pearl and pearl powder makes pill. Beeswax acts as moisturizing and the effect of adhesive at this time, and honey can be also added in preparation process.
The present invention also provides the applications of the Chinese medicine composition.The Chinese medicine composition can be used for treatment of cancer and antiviral control It treats, such as herpes zoster (popular name skirt-roof dragon), carbuncle, furuncle, sore, subcutaneous ulcer, pre-cancer, advanced cancer etc..
Embodiment
The component and parts by weight of each Chinese medicine composition are as shown in table 1, according to this field conventional method by above-mentioned Chinese traditional medicine composition Pill is made in object.
Table 1
Embodiment Black snake Sky dragon Pearl powder Cuttle bone Silver-colored pearl Beeswax
1-1 5 5 15 20 3 -
1-2 20 20 10 5 10 -
1-3 5 5 15 20 3 8
1-4 8 8 8 12 4 8
1-5 12 12 10 12 12 6
In table 1, "-" expression is not present.
Test case
The clinical effectiveness of Chinese medicine composition prepared by embodiment 1-1 to 1-5 is analyzed.
1st, case selection standard
Clinical manifestation is herpes zoster, at least an example in carbuncle, furuncle, sore, subcutaneous ulcer, pre-cancer, advanced cancer, and the age exists 10-80 year persons.Wherein 80% is accounted for herpes zoster, carbuncle, furuncle, sore, subcutaneous ulcer, cancer patient accounts for 20%.
2nd, therapeutic scheme
120 patients for meeting above-mentioned standard are randomly divided into 5 groups of embodiment groups and 1 group of reference examples group, every group 20.
(1) embodiment group:Chinese medicine composition prepared by embodiment 1-1 to 1-5 is respectively used to embodiment group 1~5 Clinical test.Administering mode be it is oral, one time 5 grams, 2 times a day.The course for the treatment of:Medication 4 weeks.
(2) control group:Acyclovir slice.1st week:Each 0.05g, 3 times a day;2nd week:Each 0.1g, 3 times a day; The 2-4 weeks:Each 0.2-0.3g, 3 times a day.The course for the treatment of:Medication 4 weeks.
3. treatment results
It needs to aviod certain food during medication.After medication 4 weeks, the ordinary circumstance of patient is observed.Made according to the pair of patient itself Therapeutic effect is assessed with reaction impression and Cure, is shown in Table 2.
Table 2
It summarizes:
(1) embodiment group:Substantially all recovery from illness with herpes zoster, carbuncle, furuncle, sore, subcutaneous ulcer, clinical symptoms pain and discomfort Sense disappears, and can restore normal life.Cancer patient takes an evident turn for the better.Side effect ratio severe patient is less.Embodiment 1-3,1-4 With 1-5 compared with embodiment 1-1 and 1-2, side effect reaction further declines.Reason may be that silver-colored pearl has certain toxicity, add Harmful effect of the silver-colored pearl to human body can be alleviated by entering beeswax.Actually Most patients have weak, head once in a while only during medication Dizzy symptom, completely disappears after drug withdrawal.
(2) control group:With herpes zoster, carbuncle, furuncle, sore, subcutaneous ulcer patient in, have 50% recovery from illness, 20% symptom is Improve, 30% symptom is without being clearly better.The medicine is to cancer patient substantially without effect.And there is gastrointestinal tract in some patientss during medication The adverse reactions such as reaction, allergy.
4th, model case is taken passages
Case 1:Patient Mr. Wang, male, 56 years old.Suffer within 2012 herpes zoster, flank pain unbearably, around has burning heat sensation, no Dare to touch.Symptom disappears after three weeks after taking.
Case 2:Patient Zheng, man, 48 years old.Arm in 2013 suffers from de- bone carbuncle, and lesion extends to armpit from hand, examined to hospital Suggest amputation after looking into.It takes an evident turn for the better after a week after taking, continues symptom after taking medicine two months and completely disappear, arm restores normal.
Case 3:Patient Zhang, female, 43 years old.Advanced lung cancer is diagnosed as within 2013, hospital thinks that survival period is one month.Clothes Medicine takes an evident turn for the better after two months, and the state of an illness is steady so far.
The above description is merely a specific embodiment, but protection scope of the present invention is not limited thereto, any Those familiar with the art in the technical scope disclosed by the present invention, can readily occur in change or replacement, should all contain Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.

Claims (10)

1. a kind of Chinese medicine composition, which is characterized in that including the following components counted in parts by weight:Black 5~20 parts of snake, sky dragon 5 ~20 parts, 5~15 parts of pearl powder, 5~20 parts of cuttle bone and silver-colored 3~10 parts of pearl.
2. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition includes counting in parts by weight Following components:Black 8~12 parts of snake, 8~12 parts of sky dragon, 8~10 parts of pearl powder, 8~12 parts of cuttle bone and silver-colored 4~6 parts of pearl.
3. Chinese medicine composition according to claim 1, which is characterized in that the Chinese medicine composition further includes beeswax 5~20 Part.
4. Chinese medicine composition according to claim 2, which is characterized in that the Chinese medicine composition further includes beeswax 8~12 Part.
5. Chinese medicine composition according to claim 3 or 4, which is characterized in that when the Chinese medicine composition includes beeswax, The crow snake, sky dragon, pearl powder, cuttle bone, silver-colored pearl and beeswax weight ratio be 6:6:5:6:6:3.
6. the preparation method of Chinese medicine composition according to claim 1 or claim 2, which is characterized in that include the following steps:
(1) black snake, sky dragon, cuttle bone are fried and smashed;
(2) it by enduring of honey, adds in the powder that step (1) obtains and mixes thoroughly, be eventually adding silver-colored pearl and pearl powder makes pill.
7. according to the method described in claim 6, it is characterized in that, the mass ratio of the powder and the honey for (1~ 1.5):1.
8. according to the preparation method of any one of claim 3 to 5 Chinese medicine composition, which is characterized in that including following step Suddenly:
(1) black snake, sky dragon, cuttle bone are fried and smashed;
(2) it by enduring of beeswax, adds in the powder that step (1) obtains and mixes thoroughly, be eventually adding silver-colored pearl and pearl powder makes pill.
9. application of any one of claim 1 to 5 Chinese medicine composition in treatment of cancer and antiviral therapy.
10. application according to claim 9, which is characterized in that the cancer includes pre-cancer and advanced cancer, described Antiviral therapy includes the treatment of herpes zoster, carbuncle, furuncle, sore, subcutaneous ulcer.
CN201810202372.0A 2018-03-12 2018-03-12 A kind of Chinese medicine composition, preparation method and its application Pending CN108159082A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1843378A (en) * 2006-02-17 2006-10-11 林则都 Traditional Chinese medicine for treating cancer and tumor and all kinds of inflammatory disease
CN101112504A (en) * 2007-08-14 2008-01-30 喻国庆 Chinese medicine for curing cancer and the method for preparing the oral liquid thereof
CN103040958A (en) * 2011-10-14 2013-04-17 李淑玉 Chinese medicament for treating herpes zoster and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1843378A (en) * 2006-02-17 2006-10-11 林则都 Traditional Chinese medicine for treating cancer and tumor and all kinds of inflammatory disease
CN101112504A (en) * 2007-08-14 2008-01-30 喻国庆 Chinese medicine for curing cancer and the method for preparing the oral liquid thereof
CN103040958A (en) * 2011-10-14 2013-04-17 李淑玉 Chinese medicament for treating herpes zoster and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨明等: "《中药药剂学》", 31 July 2016, 中国中医药出版社 *

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Application publication date: 20180615

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