CN108138142A - 繁殖用在移植中的间质干细胞（msc）的方法 - Google Patents

繁殖用在移植中的间质干细胞（msc）的方法 Download PDF

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Publication number
CN108138142A
CN108138142A CN201680061134.1A CN201680061134A CN108138142A CN 108138142 A CN108138142 A CN 108138142A CN 201680061134 A CN201680061134 A CN 201680061134A CN 108138142 A CN108138142 A CN 108138142A
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cell
cells
days
fasl
differentiation
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Chinese (zh)
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塔勒·阿尔莫格
S·亚科尼
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Quoin Pharmaceuticals Ltd
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Cellect Biotechnology Ltd
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    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
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  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201680061134.1A 2015-09-24 2016-09-22 繁殖用在移植中的间质干细胞（msc）的方法 Pending CN108138142A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562222853P 2015-09-24 2015-09-24
US62/222,853 2015-09-24
PCT/IL2016/051053 WO2017051421A1 (en) 2015-09-24 2016-09-22 Methods for propagating mesenchymal stem cells (msc) for use in transplantation

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CN108138142A true CN108138142A (zh) 2018-06-08

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US (1) US11578306B2 (cg-RX-API-DMAC7.html)
EP (1) EP3353286A1 (cg-RX-API-DMAC7.html)
JP (1) JP7011827B2 (cg-RX-API-DMAC7.html)
KR (1) KR20180050750A (cg-RX-API-DMAC7.html)
CN (1) CN108138142A (cg-RX-API-DMAC7.html)
AU (1) AU2016327285A1 (cg-RX-API-DMAC7.html)
CA (1) CA2999140A1 (cg-RX-API-DMAC7.html)
IL (1) IL258267B (cg-RX-API-DMAC7.html)
RU (1) RU2018112710A (cg-RX-API-DMAC7.html)
WO (1) WO2017051421A1 (cg-RX-API-DMAC7.html)

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Publication number Priority date Publication date Assignee Title
GB201604304D0 (en) * 2016-03-14 2016-04-27 Tigenix S A U Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease
WO2019086912A1 (en) * 2017-11-06 2019-05-09 King's College London Therapeutic substances, their preparation and diagnostic procedure
KR20210008339A (ko) * 2018-05-08 2021-01-21 셀렉트 바이오테라퓨틱스 리미티드 지방 유래 줄기 세포를 확장시키는 방법
CN113943705B (zh) * 2021-11-01 2023-09-19 北京大学口腔医学院 一种凋亡微囊泡及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007138597A2 (en) * 2006-05-31 2007-12-06 Styx Llc Methods of selecting stem cells and uses thereof
WO2015038665A1 (en) * 2013-09-11 2015-03-19 University Of Southern California A composition of stem cells having highly expressed fas ligand

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68218A (en) 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5851832A (en) 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
US5736396A (en) 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
EP0893493A3 (de) 1997-07-21 2002-12-04 Aventis Pharma Deutschland GmbH Genetisch veränderte Zellen und deren Verwendung in der Prophylaxe oder Therapie von Erkrankungen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007138597A2 (en) * 2006-05-31 2007-12-06 Styx Llc Methods of selecting stem cells and uses thereof
WO2015038665A1 (en) * 2013-09-11 2015-03-19 University Of Southern California A composition of stem cells having highly expressed fas ligand

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JAN-BERND FUNCKE 等: "TNF-related apoptosis-inducing ligand promotes human preadipocyte proliferation via ERK1/2 activation", 《FASEB J.》 *

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Publication number Publication date
RU2018112710A (ru) 2019-10-24
CA2999140A1 (en) 2017-03-30
JP7011827B2 (ja) 2022-02-10
IL258267B (en) 2022-05-01
WO2017051421A1 (en) 2017-03-30
US20180340144A1 (en) 2018-11-29
AU2016327285A1 (en) 2018-04-12
IL258267A (en) 2018-05-31
US11578306B2 (en) 2023-02-14
KR20180050750A (ko) 2018-05-15
EP3353286A1 (en) 2018-08-01
JP2018528782A (ja) 2018-10-04

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