CN108114047A - A kind of Chinese medicine composition for treating reflux esophagitis - Google Patents
A kind of Chinese medicine composition for treating reflux esophagitis Download PDFInfo
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- CN108114047A CN108114047A CN201611083757.7A CN201611083757A CN108114047A CN 108114047 A CN108114047 A CN 108114047A CN 201611083757 A CN201611083757 A CN 201611083757A CN 108114047 A CN108114047 A CN 108114047A
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- chinese medicine
- medicine composition
- reflux esophagitis
- treating reflux
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/754—Evodia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
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Abstract
The present invention discloses a kind of Chinese medicine composition for treating reflux esophagitis, and the raw material matched by following weight parts is made：6 12 parts of the coptis, 13 parts of evodia rutaecarpa, 20 30 parts of Radix Paeoniae Alba, 5 10 parts of honey-fried licorice root, 20 30 parts of raddle, 20 30 parts of calcined CONCHA ARCAE are prepared into oral preparations by the customary adjuvant and technique of pharmaceutical field.Advantageous effect：The present invention selects pure traditional Chinese medicine raw material to be formulated, and compatibility is rigorous, dialectical legislation, and prescription is proper to suit the medicine to the illness, and has no toxic side effect, treats both principal and secondary aspect of disease, cure rate is high, makes patient's livelihood restoration normal after healing.
Description
Technical field
The invention belongs to the field of Chinese medicines, are related to a kind of drug for treating reflux esophagitis.
Background technology
Reflux esophagitis refers to that gastroduodenal content reflux enters oesophagus and causes Esophageal mucosa injury, shows as burning
The heart, sour regurgitation, belch, retrosternal pain, western medical treatment is more difficult, easily recurs, the course for the treatment of is longer, and feature short treating period of the present invention is controlled
More rate is high, few side effects.
The content of the invention
The purpose of the present invention is to propose to a kind of Chinese medicine compositions for treating fluidity esophagitis, make mostly a kind of by the sick people
The drug for the treatment of.
The technical solution adopted by the present invention is：A kind of Chinese medicine composition for treating reflux esophagitis, by following weight parts
The raw material of proportioning is made：6-12 parts of the coptis, 1-3 parts of evodia rutaecarpa, 20-30 parts of Radix Paeoniae Alba, 5-10 parts of honey-fried licorice root, 20-30 parts of raddle,
20-30 parts of calcined CONCHA ARCAE is prepared into oral preparations by the customary adjuvant and technique of pharmaceutical field.
Preferred weight part of the present invention matches：6 parts of the coptis, 2 parts of evodia rutaecarpa, 30 parts of Radix Paeoniae Alba, 10 parts of honey-fried licorice root, raddle 30
Part, 30 parts of calcined CONCHA ARCAE.
After the processing method of the Chinese medicine composition aqua is weighing, each drug of mixing, 4-5 times of clear water of every part of composition
Impregnate 1 it is small when more than, decoct 40-50 minutes, filter drink-service liquid.
Further, the processing method of the Chinese medicine composition pill is mixed after Chinese medicine composition each component is crushed respectively
It closes, crosses thousand mesh sieves, pill is made, the weight 6-9g per ball in fine powder mixing tanning honey.
Applicants contemplate that reflux esophagitis belongs to the disease categories such as motherland's medicine " epigastric pain ", " sour regurgitation ", " noisy ", this
Disease changes fire and violates stomach mostly by stagnation of liver qi, caused by stomach Qi upward reversal, stagnation of liver qi, and ascending or descending movement of vital Qi imbalance, it is seen that sternal rib pain, belch
Etc. symptoms, long strongly fragrantization it is fiery, it is seen that the symptoms such as sour regurgitation, heartburn.
The present invention using eliminating evil, righting with use, treat both principal and secondary aspect of disease, treat reflux esophagitis, using tonifying liver blood, clearing away the liver-fire,
Stomach Qi, the method for invigorating the spleen gas drop, to treat both principal and secondary aspect of disease." liver is organ of general ", liver " body the moon sun ", " rushing down its son actually ", the liver five-element
Belong to wood, the heart matches fire, the heart is the son of liver, and the coptis, raddle are monarch drug in a prescription in side, and inverse stomach Qi drops in clearing liver-fire, and Radix Paeoniae Alba, honey-fried licorice root are mended
Liver blood, invigorating the spleen gas are ministerial drug altogether；The hot anti-bitter cold of evodia rutaecarpa is upset one's stomach, and calcined CONCHA ARCAE relieving haperacidity analgesic, is altogether adjuvant.
Advantageous effect：The present invention selects pure traditional Chinese medicine raw material to be formulated, and compatibility is rigorous, dialectical legislation, and prescription is proper to suit the medicine to the illness,
It has no toxic side effect, treats both principal and secondary aspect of disease, cure rate is high, makes patient's livelihood restoration normal after healing.
Specific embodiment
Embodiment 1
The present invention is a kind of Chinese medicine composition for treating reflux esophagitis, and the raw material matched by following weight parts is made：The coptis 6
Part, 1 part of evodia rutaecarpa, 20 parts of Radix Paeoniae Alba, 5 parts of honey-fried licorice root, 20 parts of raddle, 20 parts of calcined CONCHA ARCAE, by being conventionally produced for pharmaceutical field
Decocting preparation.
Embodiment 2
The present invention is a kind of Chinese medicine composition for treating reflux esophagitis, and the raw material matched by following weight parts is made：The coptis 6
Part, 1 part of evodia rutaecarpa, 30 parts of Radix Paeoniae Alba, 10 parts of honey-fried licorice root, 30 parts of raddle, 30 parts of calcined CONCHA ARCAE, by the customary adjuvant of pharmaceutical field
Electuary for oral administration is prepared into technique.
Embodiment 3
The present invention is a kind of Chinese medicine composition for treating reflux esophagitis, and the raw material matched by following weight parts is made：The coptis
12 parts, 3 parts of evodia rutaecarpa, 30 parts of Radix Paeoniae Alba, 10 parts of honey-fried licorice root, 30 parts of raddle, 30 parts of calcined CONCHA ARCAE, after each component is crushed respectively
Mixing, crosses thousand mesh sieves, and pill is made, and per ball, weight 6-9g, use are aluminum-plastic packaged in fine powder mixing tanning honey.
Clinical trial
First, differential diagnosis in tcm standard
It is all to be diagnosed as reflux esophagitis and clinical manifestation is heartburn, sour regurgitation, belch, retrosternal pain are main symptom, red tongue with yellowish fur,
The case of wiry and frequent pulse.
2nd, therapy
1. choosing 50, random grouping own control comparison method is taken, compares the pretherapy and post-treatment symptom of patient, sign and result
Variation.
2. legislation：Clearing liver-fire, along drop stomach Qi, soft liver spleen.
3. method of administration：The dosage forms such as aqua, ball, scattered can be made in Chinese medicine composition of the present invention according to the prior art.Treat water
The method of agent be add in above-mentioned 4-5 times of Chinese medicine clear water impregnate 1 it is small when more than, decoct 40 minutes or so, dry in the air it is cool after filtering mould
Material bag sealing, sterilizing, packaging, 3 bags every dose, every bag of 300ml is administered at empty stomach before meals, 3 times a day, it is every 4 it is small when once.Such as make electuary
After mixing is sieved through with thousand mesh sieves after type can crush Chinese medicine composition respectively, every bag of weight 9g.Administration：9g, 3 times/day, before meals 30 points
Clothes；During taking：January be even served as a cycle, March is as a treatment course.Medication taboo：Avoid eating the irritations such as raw and cold, pungent, tobacco and wine
Food and excessively boiling hot diet；It cannot lie down when 2 is small after meal, no longer be fed after supper；Keep mood comfortable.
3rd, parameters for observation on effect：Through 1-2 course of therapy, clinical symptoms disappear or improve, and life can take care of oneself.
4th, curative effect judging standard
1. it cures：Clinical symptoms disappear；
It is 2. effective：Medication control, recurrence period are reduced, and symptom mitigates；
3. effectively：Symptom mitigates；
It is 4. invalid：Symptom is without substantially changeing.
5th, therapeutic effect
This drug has no apparent toxic side effect in clinical practice, and upper 50 patients, which take, does not find adverse reaction.To
Upper three courses for the treatment of of Regimen Chemotherapy, treatment 50, cure rate 90%, effective percentage 100%.General curative effect see the table below one.
Ten patient's curative effect tables of table First Five-Year Plan
Claims (4)
1. a kind of Chinese medicine composition for treating reflux esophagitis, the raw material matched by following weight parts is made：6-12 parts of the coptis,
1-3 parts of evodia rutaecarpa, 20-30 parts of Radix Paeoniae Alba, 5-10 parts of honey-fried licorice root, 20-30 parts of raddle, 20-30 parts of calcined CONCHA ARCAE, by pharmaceutical field
Customary adjuvant and technique be prepared into oral preparations.
2. a kind of Chinese medicine composition for treating reflux esophagitis according to claim 1, it is characterized in that：The weight of each drug
Amount part matches：6 parts of the coptis, 2 parts of evodia rutaecarpa, 30 parts of Radix Paeoniae Alba, 10 parts of honey-fried licorice root, 30 parts of raddle, 30 parts of calcined CONCHA ARCAE.
3. a kind of Chinese medicine composition for treating reflux esophagitis according to claim 1, it is characterized in that：Its aqua adds
After work method is weighing, each drug of mixing, when every part of composition is small with 4-5 times of clear water immersion 1 more than, decoct 40-50 minutes,
Filter drink-service liquid.
4. a kind of Chinese medicine composition for treating reflux esophagitis according to claim 1, it is characterized in that：Its pill adds
Work method is mixed after Chinese medicine composition each component is crushed respectively, crosses thousand mesh sieves, and pill is made in fine powder mixing tanning honey,
The weight 6-9g per ball.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611083757.7A CN108114047A (en) | 2016-11-30 | 2016-11-30 | A kind of Chinese medicine composition for treating reflux esophagitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611083757.7A CN108114047A (en) | 2016-11-30 | 2016-11-30 | A kind of Chinese medicine composition for treating reflux esophagitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108114047A true CN108114047A (en) | 2018-06-05 |
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ID=62227433
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611083757.7A Pending CN108114047A (en) | 2016-11-30 | 2016-11-30 | A kind of Chinese medicine composition for treating reflux esophagitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT202100021992A1 (en) * | 2021-08-27 | 2023-02-27 | Neilos S R L | Composition for the prevention and/or treatment of gastric and oesophageal pathologies |
| IT202100021995A1 (en) * | 2021-08-27 | 2023-02-27 | Neilos S R L | Composition for the prevention and/or treatment of gastric and oesophageal pathologies |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178771A (en) * | 2011-04-18 | 2011-09-14 | 江西中医学院 | Medicament for treating gastrointestinal tract diseases |
-
2016
- 2016-11-30 CN CN201611083757.7A patent/CN108114047A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178771A (en) * | 2011-04-18 | 2011-09-14 | 江西中医学院 | Medicament for treating gastrointestinal tract diseases |
Non-Patent Citations (2)
| Title |
|---|
| 程炼骅等: "食管反流方治疗反流性食管炎58例", 《陕西中医》 * |
| 陈庆平: "名医印会河教授抓主症经验集粹(五)", 《中国乡村医药》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT202100021992A1 (en) * | 2021-08-27 | 2023-02-27 | Neilos S R L | Composition for the prevention and/or treatment of gastric and oesophageal pathologies |
| IT202100021995A1 (en) * | 2021-08-27 | 2023-02-27 | Neilos S R L | Composition for the prevention and/or treatment of gastric and oesophageal pathologies |
| WO2023026227A1 (en) * | 2021-08-27 | 2023-03-02 | Neilos S.r.l. | Composition for the prevention and/or treatment of gastric and esophageal diseases |
| WO2023026231A1 (en) * | 2021-08-27 | 2023-03-02 | Neilos S.r.l. | Composition for the prevention and/or treatment of gastric and esophageal diseases |
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| RJ01 | Rejection of invention patent application after publication | ||
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Application publication date: 20180605 |