CN102423436B

CN102423436B - Traditional Chinese medicine depression and lump relieving decoction for treating liver-depression and qi-stagnation type dyspepsia

Info

Publication number: CN102423436B
Application number: CN 201110416928
Authority: CN
Inventors: 丁兴年; 赵现波
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-11-25
Filing date: 2011-11-25
Publication date: 2013-06-12
Anticipated expiration: 2031-11-25
Also published as: CN102423436A

Abstract

The invention discloses a traditional Chinese medicine depression and lump relieving decoction for treating liver-depression and qi-stagnation type dyspepsia. In view of traditional Chinese medicine, dyspepsia belongs to epigastric pain and feeling of fullness, Qi dysfunction of middle jiao, dysfunction of the spleen in transport and failure of descending of the stomach-qi are commonly caused by moodiness, improper diet, insufficiency of natural endowment and the like. Liver depression and qi stagnation are critical pathologic links for dyspepsia. Based on the principles of soothing the liver, regulating the flow of qi, strengthening the spleen and stimulating the appetite, finger citron, shell of areca nut, malt, fritillariae thunbergii, albizia bark, poria, semen euryales, magnolia bark, astragalus mongholicus, licorice and the like are selected. The traditional Chinese medicines are prepared into decoction for patient administration, the decoction has relatively good treatment effect, and clinical test shows that the total effective rate can be up to 95.3%.

Description

A kind of dyspeptic Chinese medicine resolving depression of caused by hepatic stagnation qi stagnation painful abdominal mass soup that disappears for the treatment of

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of dyspeptic Chinese medicine resolving depression of caused by hepatic stagnation qi stagnation painful abdominal mass soup that disappears for the treatment of

Background technology

Functional dyspepsia refers to the persistence epigastric discomfort, can be with symptoms such as abdominal distention after meal, abdominal part flatulence, belch pantothenic acid, nausea and vomiting, many digestive tract disease and systemic disease can cause dyspepsia, as Peptic Ulcers, reflux esophagitis, hepatitis, cholecystitis etc., without other organic disease, can think functional dyspepsia if only have indigestion symptom.Functional dyspepsia generally increases with gastric motility disorder, Nervous and Mental Factors, gastric acid sensitivity, Helicobacter pylori infection is relevant.The most common with the caused by hepatic stagnation qi stagnation dyspepsia, patient's main manifestations is the gastral cavilty distension, attacks support and has a pain, and gastralgia connects the side of body, and belch is frequent, defecates not smooth, and is every because of the outbreak of emotional factors pain, thin white fur of tongue, stringy pulse.The western medical treatment curative effect is undesirable, and side effect is larger, and traditional Chinese medical science symptomatic treatment has curative effect preferably.

Summary of the invention

The purpose of this invention is to provide a kind of dyspeptic Chinese medicine resolving depression of caused by hepatic stagnation qi stagnation painful abdominal mass soup that disappears for the treatment of.Chinese medicine thinks that dyspepsia belongs to the traditional Chinese medical science " gastric abscess ", " feeling of fullness " category.How because of factors such as disorder of emotion, eating and drinking without temperance, innate deficiency, cause middle burnt disorder of movement of QI, dysfunction of the spleen in transportation, stomach-QI being unable to descend normally.Though sick at taste, in close relations with liver, and stagnation of QI due to depression of the liver is the crucial pathology link of primary disease.

The objective of the invention is to be achieved through the following technical solutions, the dyspeptic Chinese medicine resolving depression of this treatment caused by hepatic stagnation qi stagnation painful abdominal mass soup that disappears is made by the Chinese medicine of following weight portion: Fructus Citri Sarcodactylis 10-15 part, Pericarpium Arecae 12-17 part, Fructus Hordei Germinatus 15-20 part, Bulbus Fritillariae Thunbergii 10-15 part, Cortex Albiziae 13-19 part, Poria 15-20 part, Semen Euryales 10-15 part, Cortex Magnoliae Officinalis 13-19 part, Radix Astragali 10-15 part, Radix Glycyrrhizae 15-20 part.

Preferably, the dyspeptic Chinese medicine resolving depression of this treatment caused by hepatic stagnation qi stagnation painful abdominal mass soup that disappears is made by the Chinese medicine of following weight portion: 13 parts of Fructus Citri Sarcodactylis, 15 parts of Pericarpium Arecae, 17 parts, Fructus Hordei Germinatus, 13 parts of Bulbus Fritillariae Thunbergiis, 16 parts of Cortex Albiziaes, 17 parts, Poria, 12 parts of Semen Euryaless, 16 parts of Cortex Magnoliae Officinalis, 13 parts of the Radixs Astragali, 17 parts, Radix Glycyrrhizae.

Become juice by the traditional method decocting, take for the patient.

Semen Euryales reinforcing the kindey to control nocturnal emission in the side, the spleen reinforcing stopping leak; The Poria eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming; The Cortex Albiziae resolving stagnation for tranquilization, promoting blood circulation and detumescence; The Bulbus Fritillariae Thunbergii removing heat-phlegm, powder detoxifcation; The Fructus Hordei Germinatus promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite; Pericarpium Arecae therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, line water detumescence; The Cortex Magnoliae Officinalis relieving distension by promoting circulation of QI is except full; Fructus Citri Sarcodactylis activating QI to eliminate phlegm, preventing or arresting vomiting relieving distension, the liver soothing and the spleen invigorating; The Radix Astragali has benefiting QI for strengthening the superficies, arresting sweating admittedly to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema; The Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.

Clinical data

1, this group of physical data 128 examples are the patient that my institute's the spleen-stomach disease special outpatient clinic is made a definite diagnosis, and are divided at random two groups.Treatment group 64 examples, male's 40 examples wherein, women's 24 examples, at minimum 20 years old of age, maximum 50 years old, average 35.5 years old, the course of disease was the longest 4 years, and was the shortest 2 years; Matched group 64 examples, wherein the male 44, women's 20 examples, at minimum 19 years old of age, maximum 53 years old, average 36 years old, the course of disease was the longest 3 years, and was the shortest 2.5 years.Two groups of patient ages, sex, courses of disease, there are no significant for the symptom comparing difference (P＞0.05), has comparability.

2, diagnostic criteria with reference to " internal medicine handbook the 5th edition is drafted: (1) upper abdominal pain, abdominal distention, early full, belch, feel sick, the symptom such as vomiting, in 12 months, symptom continues or duration of seizure accumulative total 〉=3 months repeatedly in the past; (2) do not have the foundation (comprising superior gastrointestinal endoscopy and other coherence checks etc.) of the organic disease of these symptoms of possible explanation; (3) symptom is not alleviated because of defecation, and the change of symptom generation and defecation frequency or character is irrelevant.

3, the Therapeutic Method treatment group adopts the Chinese medicine resolving depression of the present invention painful abdominal mass soup that disappears.Fructus Citri Sarcodactylis 13g, Pericarpium Arecae 15g, Fructus Hordei Germinatus 17g, Bulbus Fritillariae Thunbergii 13g, Cortex Albiziae 16g, Poria 17g, Semen Euryales 12g, Cortex Magnoliae Officinalis 16g, Radix Astragali 13g, Radix Glycyrrhizae 17g.1 dose of every day, decocting divides and takes orally for 2 times.The oral domperidone of matched group 10mg/ time, every day 3 times; Losec 20mg/ time, every day 1 time.

4, criterion of therapeutical effect " functional dyspepsia therapeutic standards (draft) " that pass through with reference to the 13rd meeting of calendar year 2001 Traditional Chinese Medicine association internal medicine the spleen-stomach disease Professional Committee is drafted.For upper abdominal pain, big belly, early full, belch, the symptom such as feel sick are carried out rank scores, light: symptom is slight, does not affect work, life, is impatient at, and remembers 2 minutes.In: symptom is heavier, has affected work, life, still can stand, and remembers 4 minutes.Heavy: serious symptom, hinder one's work, live, endurable is remembered 6 minutes.Asymptomatic, remember 0 minute.Calculate therapeutic index according to the symptom integral before and after treatment, its formula is (symptom integral after symptom integral before treating-treatment)/symptom integral * 100% before treating.Clinical recovery: symptom disappears substantially, therapeutic index 〉=90%; Produce effects: symptom obviously alleviates, therapeutic index 〉=30%-＜60%; Invalid: symptom is without alleviating, therapeutic index＜30%.

5, two groups of cases of therapeutic outcome all take continuous 4 weeks for the treatment of as 1 course for the treatment of, are added up therapeutic outcome after finishing the course for the treatment of.Two groups of total effective rates relatively see Table one:

Table 1 liang group Clinical efficacy comparison

Annotate: compare with matched group: p＜0.01

Two groups of doing well,improving situations relatively see Table two:

Table 2 liang group cardinal symptom improvement situation relatively

Annotate: compare with matched group: p＜0.05

The specific embodiment

Embodiment one takes Fructus Citri Sarcodactylis 13g, Pericarpium Arecae 15g, Fructus Hordei Germinatus 17g, Bulbus Fritillariae Thunbergii 13g, Cortex Albiziae 16g, Poria 17g, Semen Euryales 12g, Cortex Magnoliae Officinalis 16g, Radix Astragali 13g, Radix Glycyrrhizae 17g.1 dose of every day, decocting divides and takes orally for 2 times.

Embodiment two takes Fructus Citri Sarcodactylis 10g, Pericarpium Arecae 17g, Fructus Hordei Germinatus 15g, Bulbus Fritillariae Thunbergii 15g, Cortex Albiziae 13g, Poria 20g, Semen Euryales 10g, Cortex Magnoliae Officinalis 19g, Radix Astragali 10g, Radix Glycyrrhizae 15g.1 dose of every day, decocting divides and takes orally for 2 times.

Embodiment three takes Fructus Citri Sarcodactylis 15g, Pericarpium Arecae 12g, Fructus Hordei Germinatus 20g, Bulbus Fritillariae Thunbergii 10g, Cortex Albiziae 19g, Poria 15g, Semen Euryales 15g, Cortex Magnoliae Officinalis 13g, Radix Astragali 15g, Radix Glycyrrhizae 20g.1 dose of every day, decocting divides and takes orally for 2 times.

Claims

1. treatment caused by hepatic stagnation qi stagnation dyspeptic Chinese medicine resolving depression painful abdominal mass soup that disappears is characterized in that this Chinese medicine resolving depression painful abdominal mass soup that disappears made by the Chinese medicine of following weight portion: Fructus Citri Sarcodactylis 13g, Pericarpium Arecae 15g, Fructus Hordei Germinatus 17g, Bulbus Fritillariae Thunbergii 13g, Cortex Albiziae 16g, Poria 17g, Semen Euryales 12g, Cortex Magnoliae Officinalis 16g, Radix Astragali 13g, Radix Glycyrrhizae 17g.