CN108096384A - It removes obstruction in channels to relieve pain tincture and preparation method thereof - Google Patents

It removes obstruction in channels to relieve pain tincture and preparation method thereof Download PDF

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Publication number
CN108096384A
CN108096384A CN201810055017.5A CN201810055017A CN108096384A CN 108096384 A CN108096384 A CN 108096384A CN 201810055017 A CN201810055017 A CN 201810055017A CN 108096384 A CN108096384 A CN 108096384A
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parts
liquid
time
raw material
radix
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秦少亭
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Zhengzhou Simiao Tang Biotechnology Co Ltd
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Zhengzhou Simiao Tang Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K35/583—Snakes; Lizards, e.g. chameleons
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    • A61K36/11—Pteridophyta or Filicophyta (ferns)
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    • A61K36/126—Drynaria
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    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract

It removes obstruction in channels to relieve pain tincture and preparation method thereof the invention discloses one kind, includes the raw material of following mass fraction：13 parts, 60 degree 15 parts of Radix Angelicae Sinensis, 13 parts of safflower, 13 parts of the radix paeoniae rubrathe, 13 parts of dipsacus root, 13 parts of the root of Chinese clematis, 13 parts of the rhizome of davallia, 15 parts of lycopodium calvatum, 15 parts of caulis trachelospermi, 13 parts of aconiti preparata,radix, 15 parts of Caulis Spatholobi, 13 parts of radix cyathulae, 13 parts of green peel, 13 parts of peach kernel, 13 parts windproof, 13 parts of Rhizoma Et Radix Notopterygii, 13 parts of Radix Angelicae Pubescentis, 13 parts of agalloch eaglewood, 13 parts of scorpio, 13 parts of centipede, 13 parts of long-noded pit viper, 13 parts of camphor, 13 parts of menthol, wintergreen 50 100 parts of white wine.It solves the problem of to be currently used for the few weak curative effect of swelling and pain relieving class medicament Chinese medicine liquid hold-up.

Description

It removes obstruction in channels to relieve pain tincture and preparation method thereof
Technical field
The present invention relates to the paste class pharmaceutical arts for swelling and pain relieving, and in particular to one kind is removed obstruction in channels to relieve pain tincture and its preparation Method.
Background technology
Existing swelling and pain relieving class medicament is mostly cream class medicament, and cream class medicament is divided into as ointments medicament, ointment class medicine Agent, creme etc. containing substances such as glycerine, vaseline in ointments medicament, contain the objects such as sesame oil, yellow wax in ointment class medicament Matter, it is universal containing more matrix in these above-mentioned medicaments containing white oil, paraffin, essence etc. in creme, contain instead compared with Few medicament, therefore in application, what it is into human body is more matrix rather than medicament, thus has lacking for weak curative effect Point, and wax and oil are also easy to pollution clothes and bedding in use.
The content of the invention
It removes obstruction in channels to relieve pain tincture and preparation method thereof it is an object of the invention to provide one kind, solution is currently used for swelling and pain relieving class The problem of medicament Chinese medicine liquid hold-up is few, weak curative effect.
To solve the technical issues of above-mentioned, the present invention uses following technical scheme：
One kind is removed obstruction in channels to relieve pain tincture, includes the raw material of following mass fraction：1-5 parts of Radix Angelicae Sinensis, 1-3 parts of safflower, 1-3 parts of the radix paeoniae rubrathe, river 1-3 parts disconnected, 1-3 parts of the root of Chinese clematis, 1-3 parts of the rhizome of davallia, 1-5 parts of lycopodium calvatum, 1-5 parts of caulis trachelospermi, 1-3 parts of aconiti preparata,radix, Caulis Spatholobi 1-5 It is part, 1-3 parts of radix cyathulae, 1-3 parts of green peel, 1-3 parts of peach kernel, 1-3 parts windproof, 1-3 parts of Rhizoma Et Radix Notopterygii, 1-3 parts of Radix Angelicae Pubescentis, 1-3 parts of agalloch eaglewood, complete 1-3 parts, 60 degree 1-3 parts of scorpion, 1-3 parts of centipede, 1-3 parts of long-noded pit viper, 1-3 parts of camphor, 1-3 parts of menthol, wintergreen white wine 50- 100 parts.
By purification, the tincture of removing obstruction in channels to relieve pain prepared is summarized without matrix in Chinese medicine above-mentioned raw material Beneficiating ingredient, therefore therapeutic effect is good, has no toxic side effect, and using alcohol, spraying has been made into, compared to application, each During sprinkling, dosage saves medicament less, and white wine and wintergreen can make the faster skin permeation of liquid, hair follicle, sebaceous glands, The tissues such as flesh, muscle, bone through blood circulation, are rapidly absorbed by the body, and finally reach promoting blood circulation and removing blood stasis, and quickly subside a swelling, relieve the pain Effect, since spraying has been made, easily portable also more clean environment firendly collects the white strain of ericad wooden (being commonly called as Chinese ilex) tree Branches and leaves, wintergreen can be obtained using extraction by steam distillation, wintergreen has the smell of similar wintergreen, therefore prepares Tincture of removing obstruction in channels to relieve pain also has the smell of fragrance, and the Camphorae and menthue being eventually adding also has the effect of expelling parasite, injured in the wild Afterwards, the tincture of removing obstruction in channels to relieve pain is sprayed in injury site, moreover it is possible to prevent that mosquito is close, it is the wine because if white wine to select 60 degree of white wine Smart excessive concentration when in use, can hinder liquid to be impregnated into inside of human body, and the alcohol concentration of white wine then cannot less than 60 degree The effective harmful substance killed in liquid.
A kind of method that above-mentioned raw material prepare tincture of removing obstruction in channels to relieve pain, includes the following steps：It a. will be in raw material except camphor, thin Other raw material outside lotus brain, wintergreen and 60 degree of white wine smash into the particle of soya bean size to pieces；B. after being crushed in step a Raw material are poured into pot and added water to cook；C. after the filtrate that every batch of decocts in step b is uniformly mixed, small fire slowly decocts To viscous hand, there is the phenomenon that dropping into a bead, that is, complete to decoct, obtain concentrate X；D. by camphor, menthol, wintergreen and 60 degree White wine adds in concentrate X and is uniformly mixing to obtain mixed liquor Y；E. mixed liquor Y is put into pottery cylinder interior sealing storage 27-35 days, so After filter out liquid, the liquid filtered out is finished product.
By being boiled and being refined to raw material, the substances such as vaseline, yellow wax are not added, maintain Chinese medicine most original Drug effect, the tincture small toxicity of removing obstruction in channels to relieve pain prepared, have fragrance and it is easy to carry, improve patient use Traditional Chinese medicinal spray sense Official, it is to when decocting, make the beneficiating ingredient in raw material, it is easier to be gone out by decoction, mixed liquor Y is put that raw material, which are smashed to pieces, Enter the storage of pottery cylinder interior sealing be in order to which the dregs of a decoction in mixed liquor Y is made to be precipitated in pottery cylinder, while after adding in white wine, white wine energy It reacts with noxious material therein, the noxious material in mixed liquor Y is made to degrade, while kill the bacterium in mixed liquor Y, The toxicity of liquid is reduced, and this reaction and sterilization need the time, therefore, it is necessary to seal 27-35 days, why do not select The container of other materials is stored, and is because some beneficiating ingredients in mixed liquor Y easily occur with the container of other materials Chemical reaction can make the curative effect of medicine prepared reduction.
As present invention further optimization, before adding water to cook in the step b, added in into pot and pour into former material in pot Expect that the water of 1/2 height is impregnated, when the time of immersion is 24 small.
Raw material are impregnated into the water, is the water in order to make its absorption enough, expands, so when being decocted, Its internal active ingredient more could more thoroughly be precipitated.
As present invention further optimization, what the step b was adds water to cook the raw material after crushing in batches, including First time decoction directly is carried out with big fire after the completion of impregnating, small fire is switched to after boiling water, the time that this time small fire decocts is 175 Minute to 183 minutes, after the completion of decocting for the first time, the liquid that decoction obtains is filtered out, the liquid filtered out is No.1 liquid, filters out one Add in the water of 1/2 height of surplus materials in pot after number liquid into pot again again, then carrying out second with big fire decocts, and treats water boiling Switch to small fire after rising, the time that this time small fire decocts is 120 minutes to 125 minutes, and after the completion of second decocts, decoction is obtained Liquid filter out, the liquid filtered out is No. two liquid, filters out and adds in 1/2 height of surplus materials in pot after No. two liquid into pot again again Water, then carry out third time decoction with big fire, small fire switched to after boiling water, this time small fire decoct time for 58 minutes extremely 65 minutes, after the completion of third time decocts, the liquid that decoction obtains is filtered out, the liquid filtered out is No. three liquid.
It is secondary in three batches carry out decoct be in order to which the beneficiating ingredient in medicinal material is completely extracted, avoid causing to waste, In three batches after secondary decoction, the beneficiating ingredient in the dregs of a decoction has been extracted substantially to be over, be further continued for adding water to cook it is just nonsensical, It is time-consuming and laborious.
As present invention further optimization, first time decoct when, being stirred at the uniform velocity.
When decocting for the first time, the medicinal material in pot is most complete and most containing beneficiating ingredient, therefore when decocting, it is even The benefit materials that the stirring of speed is beneficial in raw material leach, and carry out second afterwards and decoct, and raw material by decocting for the first time Softened expansion is opened by decoction made from powder, and the benefit materials contained are just easy to leach, thus second when decocting there is no need to Continue to stir.
As present invention further optimization, secondary filter is carried out to the liquid filtered out in the step e.
It is in order to which the tincture of removing obstruction in channels to relieve pain for making to prepare is purer to carry out secondary filter to the liquid filtered out in step e.
Compared with prior art, the present invention can at least reach one in following advantageous effect：
1. the smell with fragrance has promoting blood circulation and removing blood stasis, the effect quickly subside a swelling, to relieve the pain, in addition also there is wind resistance, resist The effect of cold, moisture-resistant, moreover it is possible to except numbness.
2. energy expelling mosquito, in the wild in use, better.
3. manufacturing process is simple, and is not added with the substances such as vaseline, yellow wax, the drug effect of Chinese medicine most original is maintained, and Matrix is not contained, better efficacy takes effect speed faster.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
Specific embodiment 1：
One kind is removed obstruction in channels to relieve pain tincture, includes the raw material of following mass fraction：1-5 parts of Radix Angelicae Sinensis, 1-3 parts of safflower, 1-3 parts of the radix paeoniae rubrathe, river 1-3 parts disconnected, 1-3 parts of the root of Chinese clematis, 1-3 parts of the rhizome of davallia, 1-5 parts of lycopodium calvatum, 1-5 parts of caulis trachelospermi, 1-3 parts of aconiti preparata,radix, Caulis Spatholobi 1-5 It is part, 1-3 parts of radix cyathulae, 1-3 parts of green peel, 1-3 parts of peach kernel, 1-3 parts windproof, 1-3 parts of Rhizoma Et Radix Notopterygii, 1-3 parts of Radix Angelicae Pubescentis, 1-3 parts of agalloch eaglewood, complete 1-3 parts, 60 degree 1-3 parts of scorpion, 1-3 parts of centipede, 1-3 parts of long-noded pit viper, 1-3 parts of camphor, 1-3 parts of menthol, wintergreen white wine 50- 100 parts.
By purification, the tincture of removing obstruction in channels to relieve pain prepared is summarized without matrix in Chinese medicine above-mentioned raw material Beneficiating ingredient, therefore therapeutic effect is good, has no toxic side effect, and using alcohol, spraying has been made into, compared to application, each During sprinkling, dosage saves medicament less, and white wine and wintergreen can make the faster skin permeation of liquid, hair follicle, sebaceous glands, The tissues such as flesh, muscle, bone through blood circulation, are rapidly absorbed by the body, and finally reach promoting blood circulation and removing blood stasis, and quickly subside a swelling, relieve the pain Effect, since spraying has been made, easily portable also more clean environment firendly collects the white strain of ericad wooden (being commonly called as Chinese ilex) tree Branches and leaves, wintergreen can be obtained using extraction by steam distillation, wintergreen has the smell of similar wintergreen, therefore prepares Tincture of removing obstruction in channels to relieve pain also has the smell of fragrance, and the Camphorae and menthue being eventually adding also has the effect of expelling parasite, injured in the wild Afterwards, the tincture of removing obstruction in channels to relieve pain is sprayed in injury site, moreover it is possible to prevent that mosquito is close, it is the wine because if white wine to select 60 degree of white wine Smart excessive concentration when in use, can hinder liquid to be impregnated into inside of human body, and the alcohol concentration of white wine then cannot less than 60 degree The effective harmful substance killed in liquid, scorpio, centipede and long-noded pit viper in above-mentioned raw material are air-dried ready-made dry medicine Material is sold in medicinal material market.
Specific embodiment 2：
A kind of method that above-mentioned raw material prepare tincture of removing obstruction in channels to relieve pain, includes the following steps：A. camphor, peppermint will be removed in raw material Other raw material outside brain, wintergreen and 60 degree of white wine smash into the particle of soya bean size to pieces；B. by the original after being crushed in step a Material is poured into pot and added water to cook；C. after the filtrate that every batch of decocts in step b is uniformly mixed, small fire slowly decocts extremely , there is the phenomenon that dropping into a bead in viscous hand, that is, completes to decoct, obtain concentrate X；D. it is camphor, menthol, wintergreen and 60 degree are white Wine adds in concentrate X and is uniformly mixing to obtain mixed liquor Y；E. mixed liquor Y is put into pottery cylinder interior sealing storage 27-35 days, then Liquid is filtered out, the liquid filtered out is finished product.
By being boiled and being refined to raw material, the substances such as vaseline, yellow wax are not added, maintain Chinese medicine most original Drug effect, the tincture small toxicity of removing obstruction in channels to relieve pain prepared, have fragrance and it is easy to carry, improve patient use Traditional Chinese medicinal spray sense Official, it is to when decocting, make the beneficiating ingredient in raw material, it is easier to be gone out by decoction, mixed liquor Y is put that raw material, which are smashed to pieces, Enter the storage of pottery cylinder interior sealing be in order to which the dregs of a decoction in mixed liquor Y is made to be precipitated in pottery cylinder, while after adding in white wine, white wine energy It reacts with noxious material therein, the noxious material in mixed liquor Y is made to degrade, while kill the bacterium in mixed liquor Y, The toxicity of liquid is reduced, and this reaction and sterilization need the time, therefore, it is necessary to seal 27-35 days, why do not select The container of other materials is stored, and is because some beneficiating ingredients in mixed liquor Y easily occur with the container of other materials Chemical reaction can make the curative effect of medicine prepared reduction.
Specific embodiment 3：
The present embodiment is to have carried out further instruction to step b on the basis of specific embodiment 2, adding in the step b Before water decocts, added in into pot and pour into the water of 1/2 height of raw material in pot and impregnated, time of immersion for 24 it is small when.
Raw material are impregnated into the water, is the water in order to make its absorption enough, expands, so when being decocted, Its internal active ingredient more could more thoroughly be precipitated.
Specific embodiment 4：
The present embodiment is to have carried out further instruction to step b on the basis of specific embodiment 3, is point in the step b Batch adds water to cook the raw material after crushing, including directly carrying out first time decoction with big fire after the completion of impregnating, after boiling water Switch to small fire, the time that this time small fire decocts for 175 minutes to 183 minutes, after the completion of decocting for the first time, will decoct obtained liquid Body filters out, and the liquid filtered out is No.1 liquid, and 1/2 height of surplus materials in pot is added in into pot again again after filtering out No.1 liquid Then water carries out second with big fire and decocts, small fire is switched to after boiling water, the time that this time small fire decocts for 120 minutes extremely 125 minutes, after the completion of second decocts, the liquid that decoction obtains is filtered out, the liquid filtered out is No. two liquid, after filtering out No. two liquid It adds in the water of 1/2 height of surplus materials in pot into pot again again, then carries out third time decoction with big fire, turn after boiling water For small fire, the time that this small fire decocts is 58 minutes to 65 minutes, and after the completion of third time decocts, the liquid that decoction is obtained is filtered Go out, the liquid filtered out is No. three liquid.
It is secondary in three batches carry out decoct be in order to which the beneficiating ingredient in medicinal material is completely extracted, avoid causing to waste, In three batches after secondary decoction, the beneficiating ingredient in the dregs of a decoction has been extracted substantially to be over, be further continued for adding water to cook it is just nonsensical, It is time-consuming and laborious.
Specific embodiment 5：
The present embodiment is that first time is decocted on the basis of specific embodiment 4 to have carried out further instruction, the first time Decoction when, being stirred at the uniform velocity.
When decocting for the first time, the medicinal material in pot is most complete and most containing beneficiating ingredient, therefore when decocting, it is even The benefit materials that the stirring of speed is beneficial in raw material leach, and carry out second afterwards and decoct, and raw material by decocting for the first time Softened expansion is opened by decoction made from powder, and the benefit materials contained are just easy to leach, thus second when decocting there is no need to Continue to stir.
Specific embodiment 6：
The present embodiment is to have carried out further instruction to step e on the basis of specific embodiment 2, to being filtered in the step e The liquid gone out carries out secondary filter.
It is in order to which the tincture of removing obstruction in channels to relieve pain for making to prepare is purer to carry out secondary filter to the liquid filtered out in step e.
Although reference be made herein to invention has been described for multiple explanatory embodiments of the invention, however, it is to be understood that Those skilled in the art can be designed that a lot of other modifications and embodiment, these modifications and embodiment will fall in this Shen It please be within disclosed spirit and spirit.It more specifically, can be to master in the range of disclosure and claim The building block and/or layout for inscribing composite configuration carry out a variety of variations and modifications.Except what is carried out to building block and/or layout Outside modification and improvement, to those skilled in the art, other purposes also will be apparent.

Claims (6)

  1. The tincture 1. one kind is removed obstruction in channels to relieve pain, it is characterised in that：Include the raw material of following mass fraction：1-5 parts of Radix Angelicae Sinensis, 1-3 parts of safflower, 1-3 parts of the radix paeoniae rubrathe, 1-3 parts of dipsacus root, 1-3 parts of the root of Chinese clematis, 1-3 parts of the rhizome of davallia, 1-5 parts of lycopodium calvatum, 1-5 parts of caulis trachelospermi, aconiti preparata,radix 1-3 Part, 1-5 parts of Caulis Spatholobi, 1-3 parts of radix cyathulae, 1-3 parts of green peel, 1-3 parts of peach kernel, 1-3 parts windproof, 1-3 parts of Rhizoma Et Radix Notopterygii, 1-3 parts of Radix Angelicae Pubescentis, 1-3 parts of agalloch eaglewood, 1-3 parts of scorpio, 1-3 parts of centipede, 1-3 parts of long-noded pit viper, 1-3 parts of camphor, 1-3 parts of menthol, 1-3 parts of wintergreen, 60 degree of 50-100 parts of white wine.
  2. A kind of method of tincture 2. preparation of the raw material described in claim 1 is removed obstruction in channels to relieve pain, it is characterised in that：Including walking as follows Suddenly：A. other raw material in raw material in addition to camphor, menthol, wintergreen and 60 degree of white wine are smashed into pieces soya bean size Particle；B. the raw material after being crushed in step a are poured into pot and added water to cook；C. by every batch of decocts in step b filter Uniformly after mixing, small fire is slowly decocted to viscous hand liquid, the phenomenon that dropping into a bead occurs, that is, is completed to decoct, obtained concentrate X；d. Camphor, menthol, wintergreen and 60 degree of white wine are added in into concentrate X and are uniformly mixing to obtain mixed liquor Y；E. mixed liquor Y is put into Pottery cylinder interior sealing is stored 27-35 days, then filters out liquid, the liquid filtered out is finished product.
  3. 3. according to the method described in claim 2, it is characterized in that：Before adding water to cook in the step b, add in into pot The water for entering 1/2 height of raw material in pot is impregnated, when the time of immersion is 24 small.
  4. 4. according to the method described in claim 3, it is characterized in that：It is after adding water to cook crushing in batches in the step b Raw material including directly carrying out first time decoction with big fire after the completion of impregnating, switch to small fire, this time small fire decocts after boiling water Time for 175 minutes to 183 minutes, after the completion of decocting for the first time, obtained liquid will be decocted and filtered out, the liquid filtered out is one Number liquid filters out the water for adding in 1/2 height of surplus materials in pot after No.1 liquid into pot again again, is then carried out for the second time with big fire It decocts, small fire is switched to after boiling water, the time that this time small fire decocts is 120 minutes to 125 minutes, decocts complete for the second time Afterwards, the liquid that decoction obtains is filtered out, the liquid filtered out is No. two liquid, is remained again into pot in addition pot again after filtering out No. two liquid The water of 1/2 height of excess matter, then carries out third time decoction with big fire, small fire is switched to after boiling water, and this time small fire decocts Time is 58 minutes to 65 minutes, and after the completion of third time decocts, the liquid that decoction obtains is filtered out, and the liquid filtered out is No. three Liquid.
  5. 5. according to the method described in claim 4, it is characterized in that：First time decoct when, being stirred at the uniform velocity.
  6. 6. according to the method described in claim 2, it is characterized in that：Secondary filter is carried out to the liquid filtered out in the step e.
CN201810055017.5A 2018-01-19 2018-01-19 It removes obstruction in channels to relieve pain tincture and preparation method thereof Pending CN108096384A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113797249A (en) * 2021-10-25 2021-12-17 周培荣 Traditional Chinese medicine composition for treating bone and joint pain and preparation method thereof
CN114272313A (en) * 2020-09-26 2022-04-05 贵港市平南县桂福鑫生物科技有限责任公司 External-use anti-inflammation sterilizing detumescence analgesic liquid

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US8673278B2 (en) * 2006-05-26 2014-03-18 Dr. Holmquist Healthcare, L.L.C. Bruise amelioration composition and method of use
CN106880675A (en) * 2017-03-24 2017-06-23 率秀冰 It is promoting blood circulation and removing obstruction in channels dissipate and preparation method thereof

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Publication number Priority date Publication date Assignee Title
US8673278B2 (en) * 2006-05-26 2014-03-18 Dr. Holmquist Healthcare, L.L.C. Bruise amelioration composition and method of use
CN101274067A (en) * 2007-03-26 2008-10-01 郭茂武 Medical ointment for activating blood circulation, removing stasis, dredging channels and collaterals, releasing swelling and relieving pain, and method for preparing the same
CN106880675A (en) * 2017-03-24 2017-06-23 率秀冰 It is promoting blood circulation and removing obstruction in channels dissipate and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN114272313A (en) * 2020-09-26 2022-04-05 贵港市平南县桂福鑫生物科技有限责任公司 External-use anti-inflammation sterilizing detumescence analgesic liquid
CN113797249A (en) * 2021-10-25 2021-12-17 周培荣 Traditional Chinese medicine composition for treating bone and joint pain and preparation method thereof

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Application publication date: 20180601