CN108095078A - Strengthen immunity fatigue-relieving composition and preparation method thereof - Google Patents
Strengthen immunity fatigue-relieving composition and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
The invention discloses a kind of strengthen immunity fatigue-relieving compositions, it by 20~40 parts of ginseng, 20~40 parts of American Ginseng, 30~60 parts of Radix Astragali, 30~60 parts of sealwort, 20~50 parts of Radix Ophiopogonis is raw material to be, it soaks rear heating and refluxing extraction and obtains extracting solution, it is concentrated under reduced pressure and composition stoste is made, necessary auxiliary material is added as needed on, solid particulate product, solid powder drink or liquid beverage is respectively prepared.Present composition formula composition science, dosage is reasonable, safely and effectively.There is strengthen immunity, function of relieving physical fatigue after testing.
Description
Technical field
The invention belongs to technical field of health care food, are related to a kind of health-care food composition based on herbal raw material, special
It is not to be related to one kind there is strengthen immunity and composition for relieving physical fatigue and preparation method thereof.
Background technology
With the continuous improvement of living standards, social competition is also more and more fierce.More and more people feel body not
As in the past, spent in tired out.Chronic fatigue is easy to cause immunity degradation, and physiological fatigue can make body each
System function is in a relatively low level, and body is resisted external pathogen ability and reduced, and live no power and passion are felt
It is weak tasteless, it is liable to illness, and be difficult recovery from illness.
Hypoimmunity prevents immune system from normally playing protective effect.Easily cause in the case bacterium, virus,
The infection such as fungi, therefore, it is exactly liable to illness that hypoimmunity, which most directly shows, and body consumption aggravates, and generally has constitution void
The performances such as weak, malnutritive, apathetic, fatigue and weak, appetite reduction, sleep-disorder.It analyzes according to statistics, more than 85% disease
Disease and sub-health state are all related with body immunity decline.Research is thought simultaneously, and purposeful, appropriate taking, which has to adjust, exempts from
The health food of epidemic disease function, it is highly beneficial to eliminating or avoiding sub-health state.
Ginseng, American Ginseng, Radix Astragali, sealwort, Radix Ophiopogonis, Chinese yam, Radix Paeoniae Alba, Radix Codonopsis, Radix Angelicae Sinensis, cordyceps sinensis, the stem of noble dendrobium, pilose antler, Chinese holly
Many Chinese herbal medicines such as Qi, glutinous rehmannia more or less all have effects that strengthen immunity.
CN 101711833A disclose it is a kind of treat sub-health population burnout syndrome, aids patient it is tired, it is weak, exempt from
Chinese medicine composition of epidemic disease hypofunction and preparation method thereof, main ingredient include raw Radix Astragali, Chinese yam, Radix Paeoniae Alba, Radix Codonopsis, when
Return, sealwort, ginseng, the fleece-flower root, American Ginseng, pilose antler, cordyceps sinensis, Radix Ophiopogonis, matrimony vine, many Chinese herb medicines such as prepared rhizome of rehmannia.CN
105596775A discloses a kind of drug of resistance building and preparation method thereof, has selected Schisandra chinensis, ginseng, Poria cocos, black
Sesame, American Ginseng, the fruit of glossy privet, umbellate pore furgus, Radix Codonopsis, tortoiseshell, radix pseudostellariae, rhizoma alismatis, turtle shell, Radix Astragali, eclipta, lotus seeds, Rhizoma Atractylodis Macrocephalae, mulberry
Shen, Chinese yam, tussilago, the fruit of Chinese wolfberry, hyacinth bean, lily, the seed of Oriental arborvitae, Radix Glycyrrhizae, sealwort, jujube, sword bean, radix polygonati officinalis, maltose, the stem of noble dendrobium, tangerine
A large amount of Chinese herb medicines such as skin, honey, asparagus fern, pilose antler, Radix Ophiopogonis, deer horn glue are combined preparation.
However, the existing most prescription of strengthen immunity composition is larger, Compatibility Law is complicated.Based on " Fang Congfa goes out, method with
Card is vertical, legally constituted authority neck side " principle, this kind of big prescription is more common in weight disease needs, is unsuitable for promotion and popularization instead and is used for daily health
Health care.
The content of the invention
The purpose of the present invention is being directed to hypoimmunity and fatiguability crowd, a kind of strengthen immunity fatigue-relieving is provided and is used
The preparation method of composition and said composition.
Strengthen immunity fatigue-relieving of the present invention is made with composition of following components in parts by weight of raw material
's：20~40 parts of ginseng, 20~40 parts of American Ginseng, 30~60 parts of Radix Astragali, 30~60 parts of sealwort, 20~50 parts of Radix Ophiopogonis.
The ginsengs of the parts by weight, American Ginseng, Radix Astragali, sealwort, Radix Ophiopogonis mixing are taken, 0.5~1h is soaked, is heated to reflux
Extraction, extraction fluid, the dregs of a decoction add water heating and refluxing extraction, merge extracting solution twice, are concentrated under reduced pressure into 55 DEG C of relative densities
Strengthen immunity fatigue-relieving composition stoste of the present invention is made in 1.05~1.30 concentrate.
Wherein, first time heating and refluxing extraction plus water weight be 10~14 times of drug weight, be heated to reflux for the second time
It is 8~12 times extraction plus that water weight is drug weight, each 1~2h of extraction time.
And then the present invention be by the extracting solution of the merging first with 100~200 mesh screens after, then be concentrated under reduced pressure.
Further, the present invention can add necessary auxiliary material in the above-mentioned composition stoste being prepared, and be granulated dry
It is dry to be prepared into solid particulate product or add in necessary auxiliary material, it is diluted with water and liquid beverage finished product is made.
And then the composition stoste Direct spraying can also be dried and dry powder is made by the present invention, add necessary auxiliary
Solid powder drink is made in material.
Auxiliary material of the present invention includes lactose, xylitol, citric acid, sodium citrate, malic acid, Sucralose etc., can
To be one or more therein.
Hypoimmunity is related with insufficiency of vital energy and blood, and unsaturated vapor can cause the warm deficiency of body, and viscera function declines, blood,
Body fluid generation deficiency, defence capability reduces, so as to hypoimmunity；Blood is human body by the essence of water and grain institute metaplasia of transporting and transforming function of the spleen and stomach
Indispensable nutriment, blood deficiency can cause immunity insufficient." fatigue " belongs to traditional Chinese medicine " void ", " consumptive disease ", the traditional Chinese medical science
It is mainly that a variety of causes causes spleen, liver, three dirty dysfunction of kidney to think fatigue, and the heart, lung are involved negative and positive of qi and blood imbalance and caused,
Clinically, common with asthenic symptoms, especially asthenia of qi and blood can cause physically weak overstrain.
It is integration of drinking and medicinal herbs substance that the present invention, which is used to prepare strengthen immunity fatigue-relieving with the raw material of composition, formula group
Into science, dosage is reasonable, safely and effectively.Wherein ginseng tonifying five zang organs six internal organs, YIN and YANG balance regulating reinforce vital energy, and are mainly used for invigorating the spleen and support
Stomach promotes the production of body fluid and protects lung, blood-supplementing blood-nourishing, nourshing kidney prevent prolapse, can reach the positive effect of strengthening vital QI to eliminate pathogenic factors；American Ginseng boosting qi and nourishing yin, heat-clearing life
Tianjin；Radix Astragali can tonifying Qi and lifting yang, blood-nourishing of promoting the production of body fluid is obviously promoted effect to the antibody tormation function of normal body；Sealwort tonifying Qi is supported
The moon, invigorating the spleen, moistening lung, kidney-nourishing；Radix Ophiopogonis nourishing Yin and promoting production of body fluid, ophiopogonpolysaccharide can promote humoral immunity and cellular immune function.It is above-mentioned
The effect of five kinds of raw materials are used in conjunction with, can play boosting qi and nourishing yin, and QI belonging to YANG, blood pertaining to YIN, tonifying yin also help enrich blood, so as to pin
The immunity deficiency and physical fatigue caused to insufficiency of vital energy and blood has effects that fine.
Foundation of the present invention《Health food is examined and assessment technique specification》, strengthen immunity is carried out to prepared composition
Function test.The present composition of orally administration mouse various dose 30 days has no adverse effects to mouse weight growth, to small
Mouse spleen weight ratio and thymus gland weight ratio without influence, but for mouse humoral immune function serum antibody product (P＜
0.01), NK cytoactives (P＜ 0.01) measurement result is then the positive.The result shows that present composition product has enhancing
The effect of immunity function.
And then foundation《Health food is examined and assessment technique specification》, the present composition is carried out to extenuate physical fatigue
Experiment.The present composition product of orally administration mouse various dose 30 days, high dose group can significantly extend mouse swimming with a load attached to the body
Swim the time (P＜ 0.01), reduce movement when serum urea generation (P＜ 0.01), increase liver glycogen reserves (P＜ 0.05).As a result
Show that present composition product has function of relieving physical fatigue.
Specific embodiment
With reference to specific embodiment, the present invention is described in further detail, but embodiments of the present invention and unlimited
In this.
Embodiment 1.
Selected ginseng, American Ginseng, Radix Astragali, sealwort, Radix Ophiopogonis clean up and dry.
It weighs ginseng 3kg, American Ginseng 3kg, Radix Astragali 5kg, sealwort 5kg, Radix Ophiopogonis 2kg to be uniformly mixed, adds in 12 times of drug weights
The water of amount, impregnates 0.5h, and boiling reflux extraction 1h collects extracting solution.
The water of 10 times of drug weights is added in the dregs of a decoction, boiling reflux extraction 1h collects extracting solution.
Merge extracting solution twice, 200 mesh sieve net filtrations.
Filtrate at -0.08MPa and 70 DEG C is concentrated under reduced pressure, obtains the stoste 6.5kg that 55 DEG C of relative densities are 1.25.
The lactose that 3kg crosses 80 mesh sieves is taken to add in above-mentioned stoste, stirs evenly and softwood is made, pelletized with 16 mesh sieves, 55 DEG C
Dry 40min, makes moisture≤5.0%, crosses 16 mesh sieves and removes fine powder, obtains dry particl and dispenses, 10g/ bags.
Embodiment 2.
Selected ginseng, American Ginseng, Radix Astragali, sealwort, Radix Ophiopogonis clean up and dry.
It weighs ginseng 3kg, American Ginseng 2.5kg, Radix Astragali 5kg, sealwort 4kg, Radix Ophiopogonis 3kg to be uniformly mixed, adds in 12 times of drugs
The water of weight, impregnates 0.5h, and boiling reflux extraction 1h collects extracting solution.
The water of 10 times of drug weights is added in the dregs of a decoction, boiling reflux extraction 1h collects extracting solution.
Merge extracting solution twice, 200 mesh sieve net filtrations.
Filtrate decompression is concentrated at -0.08MPa and 70 DEG C, obtains the stoste 25kg that 55 DEG C of relative densities are 1.06.
Above-mentioned stoste is refrigerated into 16h in 4 DEG C, then 200 mesh, 400 mesh, 800 mesh filter step by step, are added in obtained filtrate
Citric acid 1kg, sodium citrate 0.5kg, xylitol 6kg and purified water 175kg, mixing preparation is uniform, and high-temperature instantaneous goes out at 130 DEG C
The lower 70 DEG C of vacuum fillings of bacterium 5~8s, 0.05MPa, are cooled to room temperature, are prepared into beverage.
Embodiment 3.
Selected ginseng, American Ginseng, Radix Astragali, sealwort, Radix Ophiopogonis clean up and dry.
It weighs ginseng 2.5kg, American Ginseng 2kg, Radix Astragali 3kg, sealwort 3kg, Radix Ophiopogonis 2kg to be uniformly mixed, adds in 12 times of drugs
The water of weight, impregnates 0.5h, and boiling reflux extraction 1h collects extracting solution.
The water of 10 times of drug weights is added in the dregs of a decoction, boiling reflux extraction 1h collects extracting solution.
Merge extracting solution twice, 200 mesh sieve net filtrations.
Above-mentioned filtrate is taken, 55 DEG C of relative densities 1.08 are concentrated under reduced pressure at -0.08MPa and 70 DEG C, obtain stoste 16kg.
140 DEG C of spray dryer inlet air temperature, 70 DEG C of leaving air temp, pressure -60MPa, fluid flow rate 0.3L/h are set, it will
Obtained filtrate, which is passed through in spray dryer, to be spray-dried, and obtains stoste powder 3.8kg, incorporation xylitol 1kg, lactose 1kg
It is uniformly mixed, obtains solid powder drink.
Various embodiments above is only used for that the present invention is explained, and does not form the limit to the scope of the present invention
It is fixed.It may occur to persons skilled in the art that other it is any without departing from description of the invention principle and essence other substitute hands
Section, should all be included in the protection scope of the present invention.
Claims (9)
1. a kind of strengthen immunity fatigue-relieving composition is made of following components in parts by weight of raw material：Ginseng 20~40
Part, 20~40 parts of American Ginseng, 30~60 parts of Radix Astragali, 30~60 parts of sealwort, 20~50 parts of Radix Ophiopogonis.
2. the preparation method of strengthen immunity fatigue-relieving composition described in claim 1, be take the parts by weight ginseng,
American Ginseng, Radix Astragali, sealwort, Radix Ophiopogonis mixing, soak 0.5~1h, heating and refluxing extraction, extraction fluid, and the dregs of a decoction add water
Heating and refluxing extraction merges extracting solution twice, is concentrated under reduced pressure into the concentrate of 55 DEG C of relative densities 1.05~1.30, enhancing is made
Immunity and relieving fatigue composition stoste.
3. preparation method according to claim 2, it is characterized in that first time heating and refluxing extraction adds water weight to be drug
10~14 times of weight, it is 8~12 times second heating and refluxing extraction plus that water weight is drug weight.
4. preparation method according to claim 2, it is characterized in that 1~2h of extraction time every time.
5. preparation method according to claim 2, it is characterized in that by the extracting solution of the merging first with 100~200 mesh sieves
After filtering, then it is concentrated under reduced pressure.
6. preparation method according to claim 2, it is characterized in that adding auxiliary material, granulating and drying in the composition stoste
Prepare solid particle.
7. preparation method according to claim 2 it is characterized in that adding auxiliary material in the composition stoste, is diluted with water
Prepare liquid beverage.
8. preparation method according to claim 2, it is characterized in that composition stoste Direct spraying drying is made dry
Powder adds auxiliary material and prepares solid powder.
9. according to the preparation method described in claim 6,7 or 8, it is characterized in that the auxiliary material be lactose, xylitol, citric acid,
One or more of sodium citrate, malic acid, Sucralose.
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Cited By (3)
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| CN111990645A (en) * | 2020-09-24 | 2020-11-27 | 李红光 | Health food for enhancing immunity |
| CN114158729A (en) * | 2021-11-23 | 2022-03-11 | 中华全国供销合作总社济南果品研究院 | Composition and solid beverage containing American ginseng extract and sealwort extract |
| CN114404515A (en) * | 2022-02-08 | 2022-04-29 | 扬州诺瑞药业有限公司 | Soft-shelled turtle capsule |
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| CN114404515A (en) * | 2022-02-08 | 2022-04-29 | 扬州诺瑞药业有限公司 | Soft-shelled turtle capsule |
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