CN108078937B - 一种铝碳酸镁片及其制备方法 - Google Patents
一种铝碳酸镁片及其制备方法 Download PDFInfo
- Publication number
- CN108078937B CN108078937B CN201810022721.0A CN201810022721A CN108078937B CN 108078937 B CN108078937 B CN 108078937B CN 201810022721 A CN201810022721 A CN 201810022721A CN 108078937 B CN108078937 B CN 108078937B
- Authority
- CN
- China
- Prior art keywords
- filler
- hydrotalcite
- tablet
- microcrystalline cellulose
- magnesium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
样品 | 制酸力(ml) |
实施例1 | 327.5 |
实施例2 | 318.0 |
实施例3 | 320.4 |
对比例1 | 298.46 |
对比例2 | 321 |
市售制剂(“达喜”) | 298.2 |
样品 | 达到pH3的时间(秒) | 维持pH3~5的时间(分钟) |
实施例1 | 18 | 121 |
实施例2 | 23 | 118 |
实施例3 | 21 | 115 |
对比例1 | 30 | 85 |
对比例2 | 22 | 109 |
市售制剂(“达喜”) | 56 | 78 |
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810022721.0A CN108078937B (zh) | 2018-01-10 | 2018-01-10 | 一种铝碳酸镁片及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810022721.0A CN108078937B (zh) | 2018-01-10 | 2018-01-10 | 一种铝碳酸镁片及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN108078937A CN108078937A (zh) | 2018-05-29 |
CN108078937B true CN108078937B (zh) | 2020-01-21 |
Family
ID=62181906
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810022721.0A Active CN108078937B (zh) | 2018-01-10 | 2018-01-10 | 一种铝碳酸镁片及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108078937B (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109459543A (zh) * | 2018-12-21 | 2019-03-12 | 马德君 | 一种测试含镁无机抗酸剂体外抗酸性能的方法 |
CN111481568B (zh) * | 2020-04-22 | 2021-04-02 | 一力制药(罗定)有限公司 | 一种铝碳酸镁片及其制备工艺 |
CN114917198B (zh) * | 2022-06-22 | 2023-05-12 | 海南妙音春制药有限公司 | 一种铝碳酸镁咀嚼片及其制备方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101091719A (zh) * | 2007-07-02 | 2007-12-26 | 山东省医药工业研究所 | 质子泵抑制剂和铝碳酸镁的复方药物制剂及其制备方法 |
CN101219150A (zh) * | 2007-12-19 | 2008-07-16 | 游洪涛 | 一种快速显效的铝碳酸镁制剂及其制备工艺 |
CN101904865A (zh) * | 2010-07-23 | 2010-12-08 | 湖北丽益医药科技有限公司 | 铝碳酸镁分散片及其制备方法 |
CN102151286A (zh) * | 2010-12-13 | 2011-08-17 | 四川健能制药有限公司 | 一种铝碳酸镁片及其制备方法 |
-
2018
- 2018-01-10 CN CN201810022721.0A patent/CN108078937B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101091719A (zh) * | 2007-07-02 | 2007-12-26 | 山东省医药工业研究所 | 质子泵抑制剂和铝碳酸镁的复方药物制剂及其制备方法 |
CN101219150A (zh) * | 2007-12-19 | 2008-07-16 | 游洪涛 | 一种快速显效的铝碳酸镁制剂及其制备工艺 |
CN101904865A (zh) * | 2010-07-23 | 2010-12-08 | 湖北丽益医药科技有限公司 | 铝碳酸镁分散片及其制备方法 |
CN102151286A (zh) * | 2010-12-13 | 2011-08-17 | 四川健能制药有限公司 | 一种铝碳酸镁片及其制备方法 |
Also Published As
Publication number | Publication date |
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CN108078937A (zh) | 2018-05-29 |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Hydrotalcite tablet and preparation method thereof Effective date of registration: 20200610 Granted publication date: 20200121 Pledgee: China Everbright Bank Co.,Ltd. Haikou Branch Pledgor: HAINAN HUALON PHARMACEUTICAL Co.,Ltd. Registration number: Y2020980002930 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20230914 Granted publication date: 20200121 Pledgee: China Everbright Bank Co.,Ltd. Haikou Branch Pledgor: HAINAN HUALON PHARMACEUTICAL Co.,Ltd. Registration number: Y2020980002930 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Magnesium aluminum carbonate sheet and its preparation method Effective date of registration: 20230925 Granted publication date: 20200121 Pledgee: China Everbright Bank Co.,Ltd. Haikou Branch Pledgor: HAINAN HUALON PHARMACEUTICAL Co.,Ltd. Registration number: Y2023980058728 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |