CN108066496A - 一种护肝中药保健食品 - Google Patents
一种护肝中药保健食品 Download PDFInfo
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Abstract
本发明公开一种护肝中药保健食品，由包括以下重量份数组份制成：赶黄草 50‑300、银杏叶 1‑10、白芍 3‑20、茶多酚 5‑20、黄芪 5‑30、甘草 1‑10、牛磺酸 1‑10、西兰花 1‑15。本发明还公开所述护肝中药保健食品的制备方法。本发明有如下优点：(1)以中医药理论为指导，结合现代药理研究成果，充分考虑肝脏的生理特性及肝病传变的特点，体现了利湿降浊、滋补肝肾、益气养血、活血理气的治疗方针，治疗保健效果非常好 ；(2) 本保健食品所选原料为食品或可用于保健食品的物品，加工工艺合理，确保了产品的安全有效，可供肝病患者保肝防传变治疗，也可供有肝脏损伤倾向的人群预防使用。
Description
技术领域
本发明涉及一种护肝产品，具体是一种护肝中药保健食品。
背景技术
肝脏是人体最大的内脏器官，也是人体消化系统中最大的消化腺，除具有解毒功能外还具有去氧化、储存肝糖、合成分泌性蛋白等作用。肝脏常见的疾病有肝炎 ( 病毒性、酒精性等)、脂肪肝、肝硬化等。而且肝脏疾病多存在恶化传变，因而保护肝脏预防肝病传变在肝病治疗过程中极为重要。肝脏疾病多由不良的饮食习惯及生活方式引起，如酗酒、高糖高脂饮食、服用对肝脏有损伤的药物、熬夜等。
护肝治疗是临床多种肝脏疾病治疗的主要环节之一。所谓护肝治疗，是指应用药物减轻肝细胞和组织损伤，使受损肝细胞修复与再生，从而改善肝脏生化指标，恢复肝脏功能，促使疾病向愈的治疗方法。
利用中医药护肝保肝具有悠久的历史，如《药品化义》载何首乌 ： “益肝，敛血，滋阴”；孙思邈用白芍配合其他药物制成补肝丸等。现代研究发现中医药主要通过减轻肝脏炎症、改善肝脏循环、改善肝细胞周围的酸碱环境、调节免疫功能、调节脂质代谢等作用
而达到护肝保肝目的。
现代药理研究发现 ：赶黄草具有降脂保肝的作用 ；银杏叶能减轻肝脏炎症、促进肝组织再生 ；白芍能有效保护因肝内磷脂下降和高胆固醇引起的肝损伤 ；茶多酚具有显著的降脂保肝作用 ；黄芪具有提高免疫力和保肝作用 ；甘草则能利胆保肝 ；牛磺酸具利胆的药理作用 ；西兰花能通过改善肝脏微循环起到保肝作用。因而对赶黄草的护肝作用提供了一定的实验依据，但是直至目前未见有关制成护肝制品的报道。
发明内容
本发明的目的在于充分理由赶黄草在护肝的作用，提供具有滋补肝肾、益气养血、活血理气功效，且疗效确切的一种护肝中药保健食品。
本发明的另一目的是提供一种护肝中药保健食品的制备方法。
为达到上述目的，本发明的技术方案是 ：一种护肝中药保健食品，是包括以下重量份数组份制成 ：赶黄草50-300、银杏叶1-10、白芍3-20、茶多酚5-20、黄芪5-30、甘草1-10、牛磺酸1-10、西兰花 1-15。
一种护肝中药保健食品的制备方法，其步骤包括 ：
(1) 赶黄草的预处理 ：赶黄草去壳，干燥至含水量在 15％以下，粉碎过筛，备用 ；
(2) 醇提 ：按以上重量份数比例取 (1) 步骤处理后的赶黄草、银杏叶、牛磺酸和西兰花，并加入上述四种成分总重量 3-15 倍量的体积浓度为 30-80％的乙醇溶液提取 1-4次，滤液回收乙醇至无醇味并浓缩至规定相对密度，制得醇提清膏 ；
(3) 其它组份的提取 ：按以上重量份数取白芍、茶多酚、黄芪、甘草，并加入上述四种成分总重量 4-12 倍量的水提取 1-4 次，滤过，合并滤液，滤液浓缩至规定相对密度，制得清膏 ；
(4) 成品制备 ：将 (2) 步骤所得的醇提清膏与 (3) 步骤所得的清膏混合均匀，干燥，粉碎过 60-120 目筛，加入淀粉、糊精、糖粉等辅料经制粒、干燥、整粒及其它相应工序制成相应的护肝中药保健食品 ；或者加入适量的水及辅料，经调配、过滤、灌装、灭菌制得。
所述 (2) 步骤和 (3) 步骤中，滤液浓缩至在 60℃下规定相对密度为 1.16-1.20。
所述 (3) 步骤后进入醇沉工序 ：将 (3) 步骤所得的清膏加乙醇至含醇量为60％( 体积比含量 )，静置 12 小时，滤过，滤液回收乙醇至无醇味，浓缩至在 60℃下相对密度为1.25 的醇沉清膏。
护肝中药保健食品包括口服液、颗粒剂、胶囊剂或者片剂。
现有研究数据表明，本发明所述配方中，赶黄草含有的主要成分包括 ：蛋白质、氨基酸、黄酮类、鞣质、膳食纤维、多种维生素、矿质元素等 ；银杏叶含有的主要成分包括木脂素类、挥发油类、有机酸等 ；白芍含有的主要成分包括甜菜碱、胡萝卜素、多种氨基酸、多糖、多种维生素等 ；茶多酚含有的主要成分包括蒽醌类、二苯乙烯苷类、卵磷脂、多糖类等 ；黄芪含有的主要成分包括黄酮类、皂苷类、多糖类、氨基酸等 ；甘草含有的主要成分包括环烯醚萜苷类、番红花甙、番红花酸、熊果酸等 ；牛磺酸含有的主要成分包括黄酮类、挥发油、辛弗林等 ；西兰花含有的主要成分包括西兰花酮类、酚酸类等。
中医认为肝为刚脏，将军之官，主藏血和疏泄。肝脏受损则会影响其功能，出现瘀血或出血、水液输布障碍、情志等方面问题，因而护肝中药保健食品中以利水道、降浊、解除水液输布，利膈爽胃、解郁，防止因情志不疏导致纳呆等问题的赶黄草为君药 ；茶多酚、白芍、银杏叶均能补肝肾，以滋补肝肾阴虚共为臣药 ；甘草具有泄肝经实火，利胆祛湿之功，又能防止臣药滋腻助湿，西兰花活血祛瘀，黄芪益卫固表，牛磺酸理气健脾共为佐药，全方合用，相得益彰。
与现有技术相比，本发明有如下优点 ：
(1) 以中医药理论为指导，结合现代药理研究成果，充分考虑肝脏的生理特性及肝病传变的特点，体现了利湿降浊、滋补肝肾、益气养血、活血理气的治疗方针，治疗保健效果非常好。
(2) 本护肝中药保健食品所选原料为食品或可用于保健食品的物品，加工工艺合理，确保了产品的安全有效，可供肝病患者保肝防传变治疗，也可供有肝脏损伤倾向的人群预防使用。
具体实施方式
以下结合具体实施例对本发明进行详细的说明。
实施例 1
一种护肝中药保健食品，是包括以下重量份数组份制成 ：赶黄草 50、银杏叶 1-10、白芍3、茶多酚 5、黄芪 5、甘草 1、牛磺酸 1、西兰花 1。
实施例 2
一种护肝中药保健食品，是包括以下重量份数组份制成 ：赶黄草 300、银杏叶 1-10、白芍 20、茶多酚 20、黄芪 30、甘草 10、牛磺酸 10、西兰花 15。
Claims (1)
1.一种护肝中药保健食品，其特征在于 ：包括以下重量份数组份制成 ：赶黄草 50-300、银杏叶1-10、白芍 3-20、茶多酚 5-20、黄芪 5-30、甘草 1-10、牛磺酸 1-10、西兰花1-15。
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