CN108066238A - Application of the Chinese medicine composition with antipyretic and itching-stopping on articles for washing - Google Patents

Application of the Chinese medicine composition with antipyretic and itching-stopping on articles for washing Download PDF

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Publication number
CN108066238A
CN108066238A CN201711476955.4A CN201711476955A CN108066238A CN 108066238 A CN108066238 A CN 108066238A CN 201711476955 A CN201711476955 A CN 201711476955A CN 108066238 A CN108066238 A CN 108066238A
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Prior art keywords
itching
antipyretic
extract
stopping
chinese medicine
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CN201711476955.4A
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Chinese (zh)
Inventor
李秋芳
黄光伟
龙致科
胡永志
卢凯玲
周传检
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LIUZHOU LMZ CO Ltd
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LIUZHOU LMZ CO Ltd
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Priority to CN201711476955.4A priority Critical patent/CN108066238A/en
Publication of CN108066238A publication Critical patent/CN108066238A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D9/00Compositions of detergents based essentially on soap
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D9/00Compositions of detergents based essentially on soap
    • C11D9/04Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
    • C11D9/22Organic compounds, e.g. vitamins
    • C11D9/38Products in which the composition is not well defined
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D9/00Compositions of detergents based essentially on soap
    • C11D9/04Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
    • C11D9/44Perfumes; Colouring materials; Brightening agents ; Bleaching agents
    • C11D9/442Perfumes

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)

Abstract

The invention discloses a kind of application of antipyretic and itching-stopping Chinese medicine composition on articles for washing, belong to articles for washing applied technical field, it is added in i.e. in the technique for preparing articles for washing using antipyretic and itching-stopping Chinese medicine composition as the auxiliary element that antipyretic and itching-stopping acts in articles for washing, the antipyretic and itching-stopping Chinese medicine composition is using made of shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, dandelion extract as primary raw material.This articles for washing containing antipyretic and itching-stopping Chinese medicine composition of the present invention not only has effects that antipyretic and itching-stopping, but also safety, toxic side effect and irritation are small.

Description

Application of the Chinese medicine composition with antipyretic and itching-stopping on articles for washing
Technical field
The present invention relates to articles for washing technical field, especially a kind of safety, toxic side effect and irritation are small and with clear In the articles for washing of hot itching-relieving efficacies.
Background technology
Articles for washing is a kind of articles for daily use, can be divided into:1)Aliphatic acid soaps:Soap, perfumed soap, medicated soap, transparent soap, Soap powder;2)Strength is deoiled emulsifying:Liquid detergent(Dish washing detergent), fruits and vegetables detergent;3)People's body detergent:Shower cream is washed Shampoo, toothpaste;4)Synthetic detergent powder:Including washing powder, low sudsing detergent powder, enzymatic laundry powder, liquid detergent;5)Special fibre is special Detergent:Silk hair is net, gold is spun, color drift;6)Non- clothes washing articles for use:It is floor cleaner special, cleanser, glass cleaner, logical Use abrasive cleanser.Conventional articles for washing is limited to the functionality of human body, in order to widen articles for washing to human body Functionality, people in articles for washing one after another by adding the chemical substance with corresponding function so that some articless for washing exist Possess outside its basic washing function, be also provided with other additional functions, such as antipruritic articles for washing.
At present, antipruritic articles for washing in the market mainly adds ketoconazole, zinc pyrithione, hexamidine two(Ethoxy sulphur Acid)The chemical bactericides such as salt, climbazole, Octopirox, these chemical preservative majority irritations are larger, long-time service Insalubrity.And with economic continuous development, consumer increasingly pays close attention to the security of product, so as to increasingly advocate Natural and safety product.Therefore, a kind of articles for washing for adding substance natural, safe and with itching-relieving action will be more Meet consumer demand, so as to receive favor.
The content of the invention
It is of the invention to solve the problems, such as to be to provide a kind of application scheme of antipyretic and itching-stopping Chinese medicine composition in articles for washing, this Kind articles for washing not only has effects that antipyretic and itching-stopping, but also safety, toxic side effect and irritation are small.
The technical solution adopted by the present invention is:
Application scheme of the antipyretic and itching-stopping Chinese medicine composition of the present invention in articles for washing is exactly to prepare the technique of articles for washing It is middle to be added in antipyretic and itching-stopping Chinese medicine composition as the auxiliary element that antipyretic and itching-stopping acts in articles for washing, in the antipyretic and itching-stopping Drug composition is using shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, dandelion extract as primary raw material system Into.
In above-mentioned technical proposal, more specific technical solution can also be:It is prepared by the antipyretic and itching-stopping Chinese medicine composition Raw material in bath article technique as antipyretic and itching-stopping action component.
Into one, weight percent of the antipyretic and itching-stopping Chinese medicine composition in bath article is 1%~15%.
Into one, the shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, the weight of dandelion extract Amount is than being shaggy-fruited dittany extract:Flos Chrysanthemi Indici extract:Radix stemonae japonicae extract:Dandelion extract=1~10:1~10:1~10:1 ~10.
In above-mentioned technical proposal, more specific technical solution can also be:It is prepared by the antipyretic and itching-stopping Chinese medicine composition Raw material in hair shampoo article technique as antipyretic and itching-stopping action component.
Further, weight percent of the antipyretic and itching-stopping Chinese medicine composition in hair shampoo article is 1%~15%.
Further, the shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, the weight of dandelion extract Amount is than being shaggy-fruited dittany extract:Flos Chrysanthemi Indici extract:Radix stemonae japonicae extract:Dandelion extract=1~10:1~10:1~10:1 ~10.
In above-mentioned technical proposal, more specific technical solution can also be:It is prepared by the antipyretic and itching-stopping Chinese medicine composition Raw material in soaps cosmetic technology as antipyretic and itching-stopping action component.
Further, weight percent of the antipyretic and itching-stopping Chinese medicine composition in soaps cosmetics is 1%~15%.
Further, the shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, the weight of dandelion extract Amount is than being shaggy-fruited dittany extract:Flos Chrysanthemi Indici extract:Radix stemonae japonicae extract:Dandelion extract=1~10:1~10:1~10:1 ~10.
Wherein, shaggy-fruited dittany of the present invention, alias Philippine Flemingia Root, stereotyped writing ox, are had a strong smell, gas plant, dittany bark at seguin argyreia herb in vain, are rue Fragrant section, the perennial herb plant of shaggy-fruited dittany category basal part of stem lignifying, extract have heat-clearing and damp-drying drug, the work of wind-dispelling removing toxic substances With.
Wild chrysanthemum open country alias yellow chrysanthemum flower of the present invention, the bitter heart of a lotus seed, are composite family herbaceos perennial, wild chrysanthemum capitulum Shape it is similar to chrysanthemum, in spherical, 0.3~1cm of diameter, brown color, extract has antipyretic and antidote functions.
Radix stemonae japonicae of the present invention, the entitled tuber of stemona of Chinese medicine, alias is hundred roots, tuber of stemona grass, noisy lice medicine, medicine lice medicine, is The dried root of Stemonaceae plant radix stemonae sessilifoliae, Radix stemonae japonicae or radix stemonae tuberosae, extract is to a variety of pathogenic bacterias and skin Skin fungi has inhibitory action.
Dandelion alias Hua Hualang, Pu Gongcao of the present invention, edible dandelion, grass of wetting the bed, Western dandelion, grandmother Fourth, is composite family Dandelion herbaceos perennial, and extract has clearing heat and detoxicating and detumescence effect.
Bath article of the present invention is shower cream, bath foam etc..
Hair shampoo article of the present invention is shampoo, hair care moistens hair cream, hair growth liquor etc..
Soaps cosmetics of the present invention are handmade soap, perfumed soap, facial soap etc..
Antipyretic and itching-stopping Chinese medicine composition of the present invention is used in the form of compound Chinese medicine extract, extracting method It is that herbal mixture is mixed, is crushed, and is heated to reflux extracting with the ethyl alcohol of 4 times of amounts, then extracting solution is concentrated under reduced pressure dry Dry powdering;Wherein, extracting method is not limited to the above method, can also use supercritical extract, ultrasonic extraction etc. Method extracts;Its extractant or extractant are also not limited to above-mentioned ethyl alcohol, the substances such as water can also be used to be carried It takes or extracts.
In articles for washing of the present invention the content of antipyretic and itching-stopping Chinese medicine composition using active ingredient as 100% it is pure Extract powder example, but be not limited to extract powder or the other forms such as extracting solution or medicinal extract, when entering in other forms When extracting solution is applied to articles for washing, addition in formula should be converted to disclosed in this invention pure extract The amount of form.
Due to the adoption of the above technical scheme, the obtained advantageous effect of the present invention is:
The antipruritic auxiliary element that the present invention uses is antipyretic and itching-stopping Chinese medicine composition, the raw material day of the antipyretic and itching-stopping Chinese medicine composition So, safety, toxic side effect and irritation smaller are not easy the situation that the skins such as skin allergy, inflammation microecosystem is caused to be lacked of proper care; It is not only not easy to accumulate on skin and scalp in addition, the antipyretic and itching-stopping composition has, can also decompose, and not have quickly on the contrary Residue, and even if having the advantages that be absorbed by the skin on a small quantity and will not cause harmful effect to skin.
Specific embodiment
The present invention is made below in conjunction with specific embodiment to be described in detail into one, in following examples, involved percentage Unless otherwise indicated, it is to calculate by percentage to the quality:
Examples 1 to 3:Application of the antipyretic and itching-stopping Chinese medicine composition in shampoo
Embodiment 1 shampoo constitutive material and mass percentage content such as table 1 into embodiment 3:
Table 1
In the present embodiment 1, shampoo uses the production technology processing procedure of conventional shampoo:The injection formula moisture content in Manufacturing medicine extract machine, in 40 DEG C~70 DEG C add in APG stirrings, add in the citric acid of water dissolution, add in fatty alcohol succinate disodium, CAB, three different Stearic acid PEG-120 methyl glucosides, olive oil, stirring and dissolving are warming up to 75 DEG C~85 DEG C, add in antipyretic and itching-stopping Chinese traditional medicine composition Object stirring and dissolving is cooled to less than 40 DEG C, adds in DMDM hydantoin, essence stirring.
The production technology of the shampoo of embodiment 2 and embodiment 3 is with reference to embodiment 1.
Embodiment 4~6:Application of the antipyretic and itching-stopping Chinese medicine composition in shower cream
Embodiment 4 shower cream constitutive material and mass percentage content such as table 2 into embodiment 6:
Table 2
In the present embodiment 4, shower cream uses the production technology processing procedure of conventional shower cream:Formula water, heating are added in cream pot processed To 30 DEG C~50 DEG C addition AES stirring and dissolvings, add in APG, add in the citric acid of water dissolution, glycerine, coconut oleoyl amine methyl MEA, CAB, stirring are warming up to 70 DEG C~85 DEG C, add in antipyretic and itching-stopping Chinese medicine composition, are cooled to less than 40 DEG C, add in acyl in DMDM second Urea, essence stirring.
The production technology of the shower cream of embodiment 5 and embodiment 6 is with reference to embodiment 4.
Embodiment 7~9:Application of the antipyretic and itching-stopping Chinese medicine composition in handmade soap
Embodiment 7 handmade soap constitutive material and mass percentage content such as table 2 into embodiment 9:
Table 3
In the present embodiment 7, handmade soap uses the production technology processing procedure of conventional manual soap:Neat soap is poured into closed cream pot processed and added Heat of solution is warming up to 70 DEG C~85 DEG C, adds in antipyretic and itching-stopping Chinese medicine composition, essence, stands defoaming, cast cooling.
The production technology of the handmade soap of embodiment 8 and embodiment 9 is with reference to embodiment 7.
Antipyretic and itching-stopping is tested:
Experimental method:Itch to the cause of Hartley cavys histamine phosphate the influence of reaction
Weight 250 ~ 400g health Hartley cavys 30 are chosen, are divided into three groups at random, every group 10, ♂ ♀ are fifty-fifty.Blank Control group(Distilled water 0.1ml/100g), four taste antipyretic and itching-stopping washing group of positive control tested material(San Wei Qing Re Zhi Yang Xiji 0.1ml/100g), the tested thing liquid 0.1ml/100g of shower cream 20%, the tested thing liquid 0.1ml/100g of shampoo 20%, soaps The tested thing liquid 0.1ml/100g of product 20%).Dorsal portion shaving behind each group Hartley cavys right side on the 2nd before experiment, and in each group Accordingly experiment tested material 1 time, continuous 2 days is applied at animal shaving outside;3rd, on the experiment same day, each group animal was abraded with coarse sandpaper Behind the right side at dorsal portion shaving, to damage epidermis, skin slightly soaks blood for degree, area 1cm2, and each group animal is local to be applied accordingly outside again It tests tested material 1 time, after last applies experiment tested material 10min, starts to drip 0.01 histamine phosphate solution 0.05ml/ at the surface of a wound Only, hereafter, it is 0.05ml/ every time, until occurring every 3min by 0.02%, 0.03%, 0.04% ... ... progressive concentration Hartley cavys are turned one's head until body licks right metapedes, finally to there is the phosphoric acid given when Hartley cavys turn one's head and lick right metapedes Histamine total amount(ug)For itch-threshold, each group of data is recorded, data carry out statistics t, t, examine, the results are shown in Table 1.
It is tested using case 3,5,9, blank control sample is free of above-mentioned antipyretic and itching-stopping traditional Chinese medicine ingredients.
Experimental result see the table below:We are it can be found that the shower production of the Chinese medicine composition of the invention containing antipyretic and itching-stopping from table Product, hair washing product and soaps cosmetics play an important role of antipyretic and itching-stopping, choose Hartley cavys and carry out histamine phosphate itch-threshold reality It tests, can significantly improve phosphoric acid group by Hartley cavy histamine phosphate itch-threshold values, two groups of data carry out paired sample T's It examines, average has significant difference.
3 shampoo sample of embodiment itches to the cause of Hartley cavys histamine phosphate the influence of reaction
± S, n=10)
Antipyretic and itching-stopping is tested(Case 3):
Note:Compared with blank control group:* P < 0.05, * * P < 0.01, * * * P < 0.001
Antipyretic and itching-stopping is tested(Case 5):
Note:Compared with blank control group:* P < 0.05, * * P < 0.01, * * * P < 0.001
Antipyretic and itching-stopping is tested(Case 9)
Note:Compared with blank control group:* P < 0.05, * * P < 0.01, * * * P < 0.001
Experiment shows the present invention containing shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, dandelion extract Bath product, hair washing product and the soaps cosmetics of antipyretic and itching-stopping traditional Chinese medicine ingredients, external application can significantly improve histamine phosphate pair Hartley cavy histamine phosphate itch-threshold values are respectively provided with apparent antipyretic and itching-stopping effect.
Finally it should be noted that:The foregoing is only a preferred embodiment of the present invention, is not intended to limit the invention, Although the present invention is described in detail with reference to the foregoing embodiments, for those skilled in the art, still may be used To modify to the technical solution recorded in foregoing embodiments or carry out equivalent substitution to which part technical characteristic. Within the spirit and principles of the invention, any modification, equivalent substitution, improvement and etc. done should be included in the present invention's Within protection domain.

Claims (10)

1. application of the antipyretic and itching-stopping Chinese medicine composition in articles for washing, i.e., by antipyretic and itching-stopping in the technique for preparing articles for washing The auxiliary element that Chinese medicine composition is acted on as antipyretic and itching-stopping is added in articles for washing, the antipyretic and itching-stopping Chinese medicine composition be with Shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, dandelion extract are as made of primary raw material.
2. application of the antipyretic and itching-stopping Chinese medicine composition according to claim 1 in articles for washing, it is characterised in that:It is described Raw material of the antipyretic and itching-stopping Chinese medicine composition in bath article technique is prepared as antipyretic and itching-stopping action component.
3. application of the antipyretic and itching-stopping Chinese medicine composition according to claim 1 or 2 in articles for washing, it is characterised in that: Weight percent of the antipyretic and itching-stopping Chinese medicine composition in bath article is 1%~15%.
4. application of the antipyretic and itching-stopping Chinese medicine composition according to claim 3 in articles for washing, it is characterised in that:It is described Shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, the weight ratio of dandelion extract are shaggy-fruited dittany extract:Mother chrysanthemum Flower extract:Radix stemonae japonicae extract:Dandelion extract=1~10:1~10:1~10:1~10.
5. application of the antipyretic and itching-stopping Chinese medicine composition according to claim 1 in articles for washing, it is characterised in that:It is described Raw material of the antipyretic and itching-stopping Chinese medicine composition in hair shampoo article technique is prepared as antipyretic and itching-stopping action component.
6. application of the antipyretic and itching-stopping Chinese medicine composition in articles for washing according to claim 1 or 5, it is characterised in that: Weight percent of the antipyretic and itching-stopping Chinese medicine composition in hair shampoo article is 1%~15%.
7. application of the antipyretic and itching-stopping Chinese medicine composition according to claim 6 in articles for washing, it is characterised in that:It is described Shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, the weight ratio of dandelion extract are shaggy-fruited dittany extract:Mother chrysanthemum Flower extract:Radix stemonae japonicae extract:Dandelion extract=1~10:1~10:1~10:1~10.
8. application of the antipyretic and itching-stopping Chinese medicine composition according to claim 1 in articles for washing, it is characterised in that:It is described Raw material of the antipyretic and itching-stopping Chinese medicine composition in soaps cosmetic technology is prepared as antipyretic and itching-stopping action component.
9. application of the antipyretic and itching-stopping Chinese medicine composition in articles for washing according to claim 1 or 8, it is characterised in that: Weight percent of the antipyretic and itching-stopping Chinese medicine composition in soaps cosmetics is 1%~15%.
10. application of the antipyretic and itching-stopping Chinese medicine composition according to claim 9 in articles for washing, it is characterised in that:Institute It is shaggy-fruited dittany extract to state shaggy-fruited dittany extract, Flos Chrysanthemi Indici extract, Radix stemonae japonicae extract, the weight ratio of dandelion extract:It is wild Chrysanthemum extract:Radix stemonae japonicae extract:Dandelion extract=1~10:1~10:1~10:1~10.
CN201711476955.4A 2017-12-29 2017-12-29 Application of the Chinese medicine composition with antipyretic and itching-stopping on articles for washing Pending CN108066238A (en)

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN113693989A (en) * 2021-09-23 2021-11-26 柳州两面针股份有限公司 Traditional Chinese medicine composition for removing turbidity and relieving itching and application of traditional Chinese medicine composition in personal care products

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JP2008115133A (en) * 2006-11-07 2008-05-22 Kinjirushi Kk Atopic disease inhibiting composition
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CN104771515A (en) * 2015-04-24 2015-07-15 平阴县中医医院 External washing medicine for treating eczema and preparation method thereof

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Publication number Priority date Publication date Assignee Title
JP2008115133A (en) * 2006-11-07 2008-05-22 Kinjirushi Kk Atopic disease inhibiting composition
CN103860992A (en) * 2014-03-03 2014-06-18 马青 Traditional Chinese medicinal lotion for treating infantile eczema
CN104771515A (en) * 2015-04-24 2015-07-15 平阴县中医医院 External washing medicine for treating eczema and preparation method thereof

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113693989A (en) * 2021-09-23 2021-11-26 柳州两面针股份有限公司 Traditional Chinese medicine composition for removing turbidity and relieving itching and application of traditional Chinese medicine composition in personal care products

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