CN108042671A - A kind of Chinese medicine composition for treating gout and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating gout and preparation method thereof Download PDFInfo
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- CN108042671A CN108042671A CN201810024624.5A CN201810024624A CN108042671A CN 108042671 A CN108042671 A CN 108042671A CN 201810024624 A CN201810024624 A CN 201810024624A CN 108042671 A CN108042671 A CN 108042671A
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Chinese medicine composition for treating gout and preparation method thereof, include the component of following parts by weight：13~16 parts of Radix Angelicae Pubescentis, windproof 9~11 parts, 9~11 parts of Rhizoma Chuanxiong, 9~11 parts of Radix Angelicae Sinensis, 2~4 parts of west safflower, 4~6 parts of zaocys dhumnade, 14~16 parts of cultivated land, 9~11 parts of the radix paeoniae rubrathe, 5~7 parts of stir-baked SQUAMA MANITIS, 14~16 parts of Caulis Spatholobi, 5~7 parts of antelope's horn, 9~11 parts of Radix Glycyrrhizae, 14~16 parts of bark of ash, secondary 14~16 parts of river.The present invention mixes each component, and each component is made to play optimal effectiveness, can effectively shorten treatment cycle, and therapeutic effect is apparent, and without any side effect.
Description
Technical field
The present invention relates to the treatments of gout, and in particular to a kind of Chinese medicine composition for treating gout and preparation method thereof.
Background technology
Gout is a kind of since biosynthesis of purine is metabolized increase, and uric acid generates excessive or causes blood due to uric acid excretion is bad
Middle uric acid rise, urate crystal are deposited on caused repeated relapsing inflammatory in synovium of joint, synovial bursa, cartilage and its hetero-organization
Disease.It is since monosodium urate salt crystallization (MSU) or uric acid form over-saturation state in extracellular fluid, is organizing its crystal
It is middle deposition and caused by one group of heterologous disease.With China's improvement of living standard, dietary structure and living-pattern preservation
Goat incidence just increases rapidly, sharp ache and recurrent exerbation, it has also become perplexs a big serious problems of patient with gout, pain
Though wind does not jeopardize patient's life directly, pain during morbidity, damaged to caused by body, treat needed for all serious shadow of expense
The live and work of patient has been rung, has brought patient huge economy and mental burden.
At present, Western medicine common drug, such as allopurinol, probenecid and colchicine drug, there is certain toxic side effect,
Limit clinical application is restricted.Chinese medicine gout becomes an importance of tcm clinical practice and scientific research, Chinese medicine
Gout shows certain advantage, but the effective percentage of Chinese traditional treatment gout is relatively low, and treatment cycle is long, and very big psychology is caused to patient
Burden and physiology pain.
In view of this, it is badly in need of being improved the Traditional chinese medicine medicament of existing treatment gout, to shorten treatment cycle, improves treatment
Effect.
The content of the invention
The technical problems to be solved by the invention are that there are treatment cycle length, treatments for the existing Traditional chinese medicine medicament for treating gout
The inapparent problem of effect.
In order to solve the above-mentioned technical problem, the technical solution adopted in the present invention is to provide a kind of Chinese medicine group for treating gout
Composite medicine includes the component of following parts by weight：13~16 parts of Radix Angelicae Pubescentis, windproof 9~11 parts, 9~11 parts of Rhizoma Chuanxiong, Radix Angelicae Sinensis 9~11
Part, 2~4 parts of west safflower, 4~6 parts of zaocys dhumnade, 14~16 parts of cultivated land, 9~11 parts of the radix paeoniae rubrathe, 5~7 parts of stir-baked SQUAMA MANITIS, Caulis Spatholobi 14~
16 parts, 5~7 parts of antelope's horn, 9~11 parts of Radix Glycyrrhizae, 14~16 parts of bark of ash, secondary 14~16 parts of river.
In a preferred embodiment, the component of following parts by weight is included：15 parts of Radix Angelicae Pubescentis, windproof 10 parts, Rhizoma Chuanxiong 10
Part, 10 parts of Radix Angelicae Sinensis, 3 parts of west safflower, 5 parts of zaocys dhumnade, 15 parts of cultivated land, 10 parts of the radix paeoniae rubrathe, 6 parts of stir-baked SQUAMA MANITIS, 15 parts of Caulis Spatholobi, antelope's horn
6 parts, 10 parts of Radix Glycyrrhizae, 15 parts of bark of ash, secondary 15 parts of river.
In a preferred embodiment, the component of following parts by weight is included：16 parts of Radix Angelicae Pubescentis, windproof 9 parts, Rhizoma Chuanxiong 11
Part, 9 parts of Radix Angelicae Sinensis, 4 parts of west safflower, 4 parts of zaocys dhumnade, 16 parts of cultivated land, 9 parts of the radix paeoniae rubrathe, 5 parts of stir-baked SQUAMA MANITIS, 14 parts of Caulis Spatholobi, antelope's horn 7
Part, 9 parts of Radix Glycyrrhizae, 16 parts of bark of ash, secondary 14 parts of river.
In a preferred embodiment, the component of following parts by weight is included：13 parts of Radix Angelicae Pubescentis, windproof 11 parts, Rhizoma Chuanxiong 9
Part, 11 parts of Radix Angelicae Sinensis, 2 parts of west safflower, 6 parts of zaocys dhumnade, 14 parts of cultivated land, 11 parts of the radix paeoniae rubrathe, 4 parts of stir-baked SQUAMA MANITIS, 16 parts of Caulis Spatholobi, antelope's horn
5 parts, 11 parts of Radix Glycyrrhizae, 14 parts of bark of ash, secondary 16 parts of river.
The present invention also provides a kind of preparation method of the Chinese medicine composition of above-mentioned treatment gout, including following step
Suddenly：
Each component is mixed, adds in the water of 5~8 times of stock blend total weights, with being cooked by slow fire 20~25 minutes after being boiled by fire, is filtered
It removes slag to get liquid, 50 milliliters of oral liquid medicine is packaged into after being purified to liquid；
Or, mix each component, when adding the clear water immersion 3 of 10 times of stock blend total weights small, move into marmite and be boiled by fire, then
Be cooked by slow fire 2 it is small when, filter out liquid, then into liquid plus the clear water of 5 times of bulk pharmaceutical chemicals continue to decoct 1.5 it is small when, supernatant is taken to send
Enter evaporator concentration and medicinal extract is made, be then fed into drying baker and dried at a temperature of 150 DEG C, be ground into 350~450 mesh, sterilize
After be packed into capsule, be finished product.
Compared with prior art, the present invention mixes each component, and each component is made to play optimal effectiveness, can effectively shorten and control
The cycle is treated, therapeutic effect is apparent, and without any side effect.
Specific embodiment
The present invention provides a kind of Chinese medicine compositions for treating gout, can shorten treatment cycle, and therapeutic effect is notable.
The present invention is described in detail With reference to embodiment.
A kind of Chinese medicine composition for treating gout provided by the invention includes the component of following parts by weight：Radix Angelicae Pubescentis 13
~16 parts, windproof 9~11 parts, 9~11 parts of Rhizoma Chuanxiong, 9~11 parts of Radix Angelicae Sinensis, 2~4 parts of west safflower, 4~6 parts of zaocys dhumnade, cultivated land 14~
16 parts, 9~11 parts of the radix paeoniae rubrathe, 5~7 parts of stir-baked SQUAMA MANITIS, 14~16 parts of Caulis Spatholobi, 5~7 parts of antelope's horn, 9~11 parts of Radix Glycyrrhizae, bark of ash 14
~16 parts, secondary 14~16 parts of river.
The present invention also provides a kind of preparation method of the Chinese medicine composition of above-mentioned treatment gout, including following step
Suddenly：
Each component is mixed, adds in the water of 5~8 times of stock blend total weights, with being cooked by slow fire 20~25 minutes after being boiled by fire, is filtered
It removes slag to get liquid, 50 milliliters of oral liquid medicine is packaged into after being purified to liquid；
Or, mix each component, when adding the clear water immersion 3 of 10 times of stock blend total weights small, move into marmite and be boiled by fire, then
Be cooked by slow fire 2 it is small when, filter out liquid, then into liquid plus the clear water of 5 times of bulk pharmaceutical chemicals continue to decoct 1.5 it is small when, supernatant is taken to send
Enter evaporator concentration and medicinal extract is made, be then fed into drying baker and dried at a temperature of 150 DEG C, be ground into 350~450 mesh, sterilize
After be packed into capsule, be finished product.
First, it is below the specific introduction of each component and function：
1. Radix Angelicae Pubescentis：For the root of Umbelliferae archangel weight tooth Radix Angelicae Sinensis；Containing coumarin kind compound such as columbianetin and its
Acetic acid esters, osthole, different imperatorin, bergapten, xanthotoxin, Angelica pubescens alcohol etc.；Bitter in taste, pungent, tepor,
Return kidney, bladder warp；It can expelling wind and eliminating dampness, eliminating cold to stop pain；Cure mainly wind-cold-dampness arthralgia, lumbocrural pain, headache dentalgia etc.；Modern pharmacology is demonstrate,proved
Bright Radix Angelicae Pubescentis has the effects that analgesia, calm, anti-inflammatory, spasmolysis, antitumor, antibacterial.
It is 2. windproof：Enter bladder, lung, the spleen channel, function：Inducing diaphoresis, wind-dispelling, victory is wet, analgesic, for wind-cold-dampness arthralgia, skeletal pain.
3. Rhizoma Chuanxiong：Return liver, courage, pericardium channel, major function：Blood-activating and qi-promoting, wind-expelling pain-stopping, arthralgia pain due to rheumatism.
4. Radix Angelicae Sinensis：Return liver, the heart, the spleen channel, replenishing and activating blood, and simultaneous energy eliminating cold to stop pain, wind-damp numbness, the pain of ulcer sore pain
Card.
5. west safflower：Invigorate blood circulation, Stasis through, traumatic injury, for blood stasis and swelling pain and joint pain, angina pectoris and arteries and veins
Guan Yan.
6. zaocys dhumnade：The hirudo leech of internal organ are removed for Chordata Colubridae animal zaocys dhumnade；Sweet and neutral, return liver warp；It dispels
Wind, dredging collateral stop convulsion；For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial paralysis, hemiplegia, spasm of twitching, lockjaw, leprosy
Mange, scrofula malignant sore etc..
7. cultivated land：It is processed for Radix Rehmanniae is processed；Nature and flavor are sweet, tepor, return liver and kidney channel；Can enrich blood yin-nourishing, replenishing essence benefit
Marrow；The all diseases of the deficiency of blood are cured mainly, sweet Wen Zhirun, tonifying yin strengthening the essence is with green blood, for the key medicine of blood-nourishing qi-restoratives.
8. the radix paeoniae rubrathe：Hardship is slightly cold, return liver warp, has clearing heat and cooling blood, removing blood stasis and analgesics effect；Its principle active component is Chinese herbaceous peony
Glycosides has platelet aggregation-against, reduces blood viscosity, reduces packed cell volume, it is strongly fragrant to improve hemorheology index, inhibition bile
The product factor reduces the effects that plasma thromboxane B2 (TX), cholagogic, diuresis.
9. stir-baked SQUAMA MANITIS：Taste is salty, cold nature, enters liver, stomach two passes through；With newborn, anti-stain in solid work(under blood circulation promoting and dispersing pathogen accumulation, promoting menstruation
Energy.
10. Caulis Spatholobi：It activates blood and relax tendons, nourishing blood for regulating menstruation is mainly used for the symptoms such as numb in every limb, quadriplegia, arthralgia pain due to rheumatism.
11. antelope's horn：It is salty, cold；Liver, the heart channel of Hang-Shaoyin；Suppressing hyperactive liver for calming endogenous wind clears liver and improve vision, is clearing heat and detoxicating；Main liver wind agitation, frightened epilepsy are taken out
It jerks；Liver-yang hyperactivity is had a dizzy spell；Liver-fire flaming, hot eyes headache.
12. Radix Glycyrrhizae：The thoughts of returning home, lung, spleen, stomach；It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription；
For weakness of the spleen and the stomach.
13. bark of ash：It is pungent, bitter, it puts down；Return stomach, liver, gallbladder channel.Wind-damp dispelling, clearing away damp-heat, stopping numbness pain；For muscle arteries and veins contraction, joint
Ache, afternoon tidal fever, infantile malnutrition generates heat；Modern pharmacology proves that bark of ash has the effects that anti-inflammatory, analgesia.
14. river is secondary：Many effects such as filling liver kidney, strengthening the bones and muscles, blood pressure lowering, tocolysis cure mainly spinal column ache, impotence, frequent micturition, small
Just the heeltap, arthralgia pain due to rheumatism.
2nd, it is below enforceable specific embodiment：
Embodiment one
15 parts of Radix Angelicae Pubescentis, windproof 10 parts, 10 parts of Rhizoma Chuanxiong, 10 parts of Radix Angelicae Sinensis, 3 parts of west safflower, 5 parts of zaocys dhumnade, 15 parts of cultivated land, the radix paeoniae rubrathe 10
Part, 6 parts of stir-baked SQUAMA MANITIS, 15 parts of Caulis Spatholobi, 6 parts of antelope's horn, 10 parts of Radix Glycyrrhizae, 15 parts of bark of ash, secondary 15 parts of river.
Embodiment two
16 parts of Radix Angelicae Pubescentis, windproof 9 parts, 11 parts of Rhizoma Chuanxiong, 9 parts of Radix Angelicae Sinensis, 4 parts of west safflower, 4 parts of zaocys dhumnade, 16 parts of cultivated land, 9 parts of the radix paeoniae rubrathe, big gun
5 parts of naze, 14 parts of Caulis Spatholobi, 7 parts of antelope's horn, 9 parts of Radix Glycyrrhizae, 16 parts of bark of ash, secondary 14 parts of river.
Embodiment three
13 parts of Radix Angelicae Pubescentis, windproof 11 parts, 9 parts of Rhizoma Chuanxiong, 11 parts of Radix Angelicae Sinensis, 2 parts of west safflower, 6 parts of zaocys dhumnade, 14 parts of cultivated land, 11 parts of the radix paeoniae rubrathe,
4 parts of stir-baked SQUAMA MANITIS, 16 parts of Caulis Spatholobi, 5 parts of antelope's horn, 11 parts of Radix Glycyrrhizae, 14 parts of bark of ash, secondary 16 parts of river.
Wherein the ratio of each component can play maximum effect in embodiment one, be preferred embodiment.
Embodiment one makes respectively according to following two steps：
Each component is mixed, adds in the water of 5~8 times of stock blend total weight, with being cooked by slow fire 20~25 minutes after being boiled by fire, mistake
Slag is filtered off to get liquid, liquid is packaged into 50 milliliters of oral liquid medicine；
Each component is mixed, when adding the clear water immersion 3 of 10 times of stock blend total weights small, big fire in marmite is moved into and extremely boils, Ran Houwen
Fire decoct 2 it is small when, filter out liquid, then into liquid plus the clear water of 5 times of stock blend total weights continue to decoct 1.5 it is small when, take supernatant
Liquid is sent into evaporator concentration and medicinal extract is made, and is then fed into drying baker and is dried at a temperature of 150 DEG C, is ground into 350~450 mesh,
Capsule is packed into after disinfection, is finished product.
3rd, it is below experimental data：
1. test example
Choose 120 cases for having made a definite diagnosis gout, wherein male 67, women 53, max age person 73 years old, minimal ages person
19 years old.More than patient takes the oral liquid of the preparation of the embodiment of the present invention 1,3 times a day, 50 milliliters every time.It is controlled for 109 after medication
More, 11 improvements, 0 invalid, and statistical result showed cure rate is up to 90.8%, and total effective rate is up to 100%.It is most long in more than case
Medication time is 120 days, and most short is only 30 days, is had no adverse reaction during medication.The present invention has for treating gout
Good healing effect.
2. model case：
（1）Case 1
Zeng, female, 28 years old, there is double-legged thumb pain in urarthritis more than 3 years, before 3 years, and night aggravates, delays daytime
Solution, also with fever, general weakness is diagnosed as urarthritis acute stage, by oral administration Allopurinol, colchicum in local hospital
Remission after alkali.But said medicine less effective is treated in this year, the last time breaking-out is in great pain, and oral drugs are difficult to
Alleviate.
Therapeutic modality：The oral medicine prepared using embodiment 1 is treated.
Curative effect：Pain, swelling mitigate after 30 days,
After 4 months, symptom disappears,
6 months or more, symptom did not occurred repeatedly again, and every Index for examination is also all normal.
（2）Case 2
Zhu, man, 46 years old.Left lower extremity pain is had a surplus July, before by Western medicine symptom management, is examined through looking into as rheumatism gout.
Therapeutic modality：The capsule of the preparation of embodiment 1 is taken, 3 times a day, 5 tablets each time.
Curative effect：Pain relief after 10 days, after 1 month swelling substantially eliminate, recover within 2 months normal.
（3）Case 3
Journey, man, 68, gout for many years, all ate much by Chinese and Western medicine, and disease is not cured, and hepatic and renal function is severely impacted.
Therapeutic modality：First trimester takes the oral medicine treatment of the preparation of embodiment 1, and capsule is used after three months.
Curative effect：There is a change for the better after three months, pain frequency reduce, complexion is ruddy by switching in vain, after be changed to capsule, feelings
Condition is good, adheres to taking, and improves.
The invention is not limited in above-mentioned preferred forms, and anyone should learn that is made under the enlightenment of the present invention
Structure change, the technical schemes that are same or similar to the present invention are each fallen within protection scope of the present invention.
Claims (5)
1. a kind of Chinese medicine composition for treating gout, which is characterized in that include the component of following parts by weight：Radix Angelicae Pubescentis 13~16
Part, windproof 9~11 parts, 9~11 parts of Rhizoma Chuanxiong, 9~11 parts of Radix Angelicae Sinensis, 2~4 parts of west safflower, 4~6 parts of zaocys dhumnade, cultivated land 14~16
Part, 9~11 parts of the radix paeoniae rubrathe, 5~7 parts of stir-baked SQUAMA MANITIS, 14~16 parts of Caulis Spatholobi, 5~7 parts of antelope's horn, 9~11 parts of Radix Glycyrrhizae, bark of ash 14~
16 parts, secondary 14~16 parts of river.
2. Chinese medicine composition according to claim 1, which is characterized in that include the component of following parts by weight：Radix Angelicae Pubescentis
15 parts, windproof 10 parts, 10 parts of Rhizoma Chuanxiong, 10 parts of Radix Angelicae Sinensis, 3 parts of west safflower, 5 parts of zaocys dhumnade, 15 parts of cultivated land, 10 parts of the radix paeoniae rubrathe, stir-baked SQUAMA MANITIS 6
Part, 15 parts of Caulis Spatholobi, 6 parts of antelope's horn, 10 parts of Radix Glycyrrhizae, 15 parts of bark of ash, secondary 15 parts of river.
3. Chinese medicine composition according to claim 1, which is characterized in that include the component of following parts by weight：Radix Angelicae Pubescentis
16 parts, windproof 9 parts, 11 parts of Rhizoma Chuanxiong, 9 parts of Radix Angelicae Sinensis, 4 parts of west safflower, 4 parts of zaocys dhumnade, 16 parts of cultivated land, 9 parts of the radix paeoniae rubrathe, 5 parts of stir-baked SQUAMA MANITIS,
14 parts of Caulis Spatholobi, 7 parts of antelope's horn, 9 parts of Radix Glycyrrhizae, 16 parts of bark of ash, secondary 14 parts of river.
4. Chinese medicine composition according to claim 1, which is characterized in that include the component of following parts by weight：Radix Angelicae Pubescentis
13 parts, windproof 11 parts, 9 parts of Rhizoma Chuanxiong, 11 parts of Radix Angelicae Sinensis, 2 parts of west safflower, 6 parts of zaocys dhumnade, 14 parts of cultivated land, 11 parts of the radix paeoniae rubrathe, stir-baked SQUAMA MANITIS 4
Part, 16 parts of Caulis Spatholobi, 5 parts of antelope's horn, 11 parts of Radix Glycyrrhizae, 14 parts of bark of ash, secondary 16 parts of river.
5. the preparation method of the Chinese medicine composition for the treatment of gout as described in claim 1, which is characterized in that including following step
Suddenly：
Each component is mixed, adds in the water of 5~8 times of stock blend total weights, with being cooked by slow fire 20~25 minutes after being boiled by fire, is filtered
It removes slag to get liquid, 50 milliliters of oral liquid medicine is packaged into after being purified to liquid；
Or, mix each component, when adding the clear water immersion 3 of 10 times of stock blend total weights small, move into marmite and be boiled by fire, then
Be cooked by slow fire 2 it is small when, filter out liquid, then into liquid plus the clear water of 5 times of bulk pharmaceutical chemicals continue to decoct 1.5 it is small when, supernatant is taken to send
Enter evaporator concentration and medicinal extract is made, be then fed into drying baker and dried at a temperature of 150 DEG C, be ground into 350~450 mesh, sterilize
After be packed into capsule, be finished product.
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Application publication date: 20180518 |