CN108041596A - A kind of arithoke relieving alcoholism and protecting liver piece and preparation method thereof - Google Patents
A kind of arithoke relieving alcoholism and protecting liver piece and preparation method thereof Download PDFInfo
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- CN108041596A CN108041596A CN201711289799.0A CN201711289799A CN108041596A CN 108041596 A CN108041596 A CN 108041596A CN 201711289799 A CN201711289799 A CN 201711289799A CN 108041596 A CN108041596 A CN 108041596A
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- arithoke
- protecting liver
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- 210000004185 liver Anatomy 0.000 title claims abstract description 74
- 208000007848 Alcoholism Diseases 0.000 title claims abstract description 67
- 201000007930 alcohol dependence Diseases 0.000 title claims abstract description 67
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- 239000000284 extract Substances 0.000 claims abstract description 170
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 70
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims abstract description 68
- 244000019459 Cynara cardunculus Species 0.000 claims abstract description 64
- 235000019106 Cynara scolymus Nutrition 0.000 claims abstract description 64
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 40
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 40
- 244000046146 Pueraria lobata Species 0.000 claims abstract description 40
- 235000010575 Pueraria lobata Nutrition 0.000 claims abstract description 40
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 38
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 37
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 35
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 35
- 240000006365 Vitis vinifera Species 0.000 claims abstract description 35
- 235000014787 Vitis vinifera Nutrition 0.000 claims abstract description 35
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 35
- 239000011718 vitamin C Substances 0.000 claims abstract description 35
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 34
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims abstract description 34
- 235000019359 magnesium stearate Nutrition 0.000 claims abstract description 34
- 239000000463 material Substances 0.000 claims abstract description 34
- 229930195725 Mannitol Natural products 0.000 claims abstract description 28
- 239000000594 mannitol Substances 0.000 claims abstract description 28
- 235000010355 mannitol Nutrition 0.000 claims abstract description 28
- 239000002245 particle Substances 0.000 claims abstract description 28
- 239000000835 fiber Substances 0.000 claims abstract description 16
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- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 15
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 230000036541 health Effects 0.000 description 5
- 235000016520 artichoke thistle Nutrition 0.000 description 3
- 235000013339 cereals Nutrition 0.000 description 3
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- 235000009508 confectionery Nutrition 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229930003944 flavone Natural products 0.000 description 2
- -1 flavone compound Chemical class 0.000 description 2
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- 235000013305 food Nutrition 0.000 description 2
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- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 2
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- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- YDDUMTOHNYZQPO-RVXRWRFUSA-N Cynarine Chemical compound O([C@@H]1C[C@@](C[C@H]([C@@H]1O)O)(OC(=O)\C=C\C=1C=C(O)C(O)=CC=1)C(O)=O)C(=O)\C=C\C1=CC=C(O)C(O)=C1 YDDUMTOHNYZQPO-RVXRWRFUSA-N 0.000 description 1
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- SEBFKMXJBCUCAI-UHFFFAOYSA-N NSC 227190 Natural products C1=C(O)C(OC)=CC(C2C(OC3=CC=C(C=C3O2)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-UHFFFAOYSA-N 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
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- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
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- 229960001230 asparagine Drugs 0.000 description 1
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- 210000000988 bone and bone Anatomy 0.000 description 1
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- 150000007946 flavonol Chemical class 0.000 description 1
- HVQAJTFOCKOKIN-UHFFFAOYSA-N flavonol Natural products O1C2=CC=CC=C2C(=O)C(O)=C1C1=CC=CC=C1 HVQAJTFOCKOKIN-UHFFFAOYSA-N 0.000 description 1
- 235000011957 flavonols Nutrition 0.000 description 1
- 229940068517 fruit extracts Drugs 0.000 description 1
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- SEBFKMXJBCUCAI-HKTJVKLFSA-N silibinin Chemical compound C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC=C(C=C3O2)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-HKTJVKLFSA-N 0.000 description 1
- 229960004245 silymarin Drugs 0.000 description 1
- 235000017700 silymarin Nutrition 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Botany (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides a kind of arithoke relieving alcoholism and protecting liver piece and preparation method thereof, which includes the component of following weight ratio：Cynara scolymus extracts：3 parts~30 parts；Raisin tree seed extract：1 part~10 parts；Wolfberry fruit extract：1 part~10 parts；Kudzu root extract：1 part~10 parts；The preparation method includes：The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；Raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and the cynara scolymus extracts are mixed, are pelletized, is dry, sieving, obtain particle；The particle is mixed with magnesium stearate again, tabletting is to get to final relieving alcoholism and protecting liver piece.Arithoke relieving alcoholism and protecting liver piece provided by the invention has effects that relieving alcoholism and protecting liver, moistening lung nourshing kidney, Shengyang Zhixie etc. are many.
Description
Technical field
This application involves technical field of health care products more particularly to a kind of arithoke relieving alcoholism and protecting liver piece and preparation method thereof.
Background technology
Arithoke also known as food support cynara scolymus, cynara scolymus, globe artichoke, are composite family cynara scolymus category, originate in Mediterranean western part and middle part,
Roman has started to eat before 2,000 years, and current American-European countries's plantation is more, most with France's plantation.During 19th century were passed to
State is distributed at present on Shanghai, Zhejiang, Hunan, Beijing, Yunnan, Shaanxi Province, Shandong and other places.
Arithoke is full of nutrition, in every 100 grams of edible parts, aqueous 80.5 grams, and 0.2 gram of fat, 2.8 grams of protein, sugar
9.9 grams of class, 60 milligrams of retinol1,8 milligrams of vitamin C, 51 milligrams of calcium, 69 milligrams of phosphorus, 1.5 milligrams of iron also have the mankind
The cinarine of benefit, asparagine and flavone compound etc..Arithoke arithoke rich in a variety of nutriments not only has food
With value, also there is very high medical value.In Europe, arithoke is always to be used for treating dyspeptic herbal medicine, modern section
It learns research and shows that cynara scolymus extracts can be used for the disease of digestive tracts such as treatment abdominal pain, abdominal distension, nausea；Many experiments are it is also shown that arithoke
Extract can reduce blood fat, so as to the generation of prevention of arterial atherosis；Flavone compound in arithoke has a variety of lifes
Object activity, clinical drug research show that it has protection cardiovascular and cerebrovascular, antitumor, anti-inflammatory and antalgic, protects liver, antibacterial disease-resistant
The multiple efficacies such as poison.
Scientific investigations showed that arithoke can form layer protecting film on liver cell surface layer, it can substantially reduced excess intake
Damage of the alcohol to liver, for the symptom of some acute liver poisonings, arithoke has certain detoxicating functions, it can also be reduced
The liver toxic and side effect of some prescription medicines.In addition, arithoke has maintenance and palingenesis for liver cell, and enhance normal liver cell
The protein synthesis of nucleotide because liver cell is a small number of organs with protein power of regeneration in human body, passes through
The synthesis of stimulating protein can promote the reparation of liver cell, encourage cell neogenesis, have apparent protection and stablize liver cell
Effect, have clear improvement to hepatopath.Silymarin contained by arithoke is a kind of very strong flavonol of oxidation resistance,
It can promote hepatocytes secrete antioxidative enzyme and protect liver plasma membrane, increase the removing toxic substances of liver cell and confrontation poisoning substances
Ability.
Matrimony vine as a kind of common Chinese medicine, have moistening lung clearing liver, nourshing kidney, QI invigorating, production of sperm, supporing yang, wind-dispelling, improving eyesight,
Many effects such as strengthening the bones and muscles；Hoveniae semoveniae semen has the effect of relieving alcoholism, relieving restlessness of quenching the thirst, preventing or arresting vomiting, sharp stool and urine；Pueraria lobata can expelling pathogenic factors from muscles and skin move back
Heat, promoting eruption promote the production of body fluid to quench thirst, Shengyang Zhixie.Arithoke is aided with health products made of these three medicinal materials and is grown with relieving alcoholism and protecting liver, moistening lung
Many effects such as kidney, Shengyang Zhixie, long-term use are remarkably contributing to health.
But the artichoke health-care products in China market are mostly that arithoke beverage or arithoke powder are taken, it is necessary to brew at present, and
The health products of solid tablet are convenient to take, and active ingredient ratio higher, and therefore, that develops a kind of sheet is rich in arithoke elite
The health products of object have good meaning for consumer.
The content of the invention
It is an object of the invention to provide a kind of arithoke relieving alcoholism and protecting liver piece and preparation method thereof, to solve domestic market
The artichoke health-care products of upper solid tablet are less and the problem of effect is more single.
In a first aspect, the present invention provides a kind of arithoke relieving alcoholism and protecting liver piece, include the component of following weight ratio：
Cynara scolymus extracts：3 parts~30 parts；
Raisin tree seed extract：1 part~10 parts；
Wolfberry fruit extract：1 part~10 parts；
Kudzu root extract：1 part~10 parts.
Further include the component of following weight ratio：
Mannitol：0.5 part~2 parts；
D-sorbite：1 part~2 parts；
Vitamin C：1 part~5 parts；
Magnesium stearate：0.5 part~1 part.
Also include 30 parts~91 parts of auxiliary material；
Preferably, the auxiliary material includes filler and adhesive；
Preferably, the filler includes starch, Icing Sugar and dextrin；
Preferably, described adhesive includes one kind or several in starch slurry, sodium carboxymethylcellulose and hydroxypropyl cellulose
Kind.
Preferably, the weight of the relieving alcoholism and protecting liver piece every is 0.5g~2g.
Second aspect, the present invention also provides a kind of preparation methods of arithoke relieving alcoholism and protecting liver piece, comprise the following steps：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and
The cynara scolymus extracts are uniformly mixed, wet granulation, drying, whole grain, particle is obtained, wherein each component is in the shield of relieving the effect of alcohol
Weight ratio in liver slice is as follows：
Cynara scolymus extracts：3 parts~30 parts；
Raisin tree seed extract：1 part~10 parts；
Wolfberry fruit extract：1 part~10 parts；
Kudzu root extract：1 part~10 parts；
Mannitol：0.5 part~2 parts；
D-sorbite：1 part~2 parts；
Vitamin C：1 part~5 parts；
Auxiliary material：30 parts~91 parts；
Preferably, the auxiliary material includes filler and adhesive；
Preferably, the filler includes starch, Icing Sugar and dextrin；
Preferably, described adhesive includes one kind or several in starch slurry, sodium carboxymethylcellulose and hydroxypropyl cellulose
Kind.
The relieving alcoholism and protecting liver piece semi-finished product are mixed with magnesium stearate, tabletting is to get to final relieving alcoholism and protecting liver piece,
In, weight ratio of the magnesium stearate in the relieving alcoholism and protecting liver piece is 0.5 part~1 part.
Preferably, the arithoke petal by non-fiber lignifying is cleaned, dries, dries, crushing, and obtains cynara scolymus extracts
The step of in, for the cynara scolymus extracts to be powdered, grain size is less than 100 μm.
Preferably, it is described to give birth to raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, dimension
In the step of plain C, auxiliary material and the cynara scolymus extracts are mixed, pelletized, is dry, sieving, obtain particle, the granulation is wet method
One kind in granulation and dry granulation.
From above technical scheme, the present invention provides a kind of arithoke relieving alcoholism and protecting liver pieces, are carried including 3 parts~30 portions arithokes
Take object, 1 part~10 parts raisin tree seed extracts, 1 part~10 parts wolfberry fruit extracts, 1 part~10 parts kudzu root extracts；Further include 0.5
Part~2 portions of mannitol, 1 part~2 parts D-sorbites, 1 part~5 parts vitamin Cs, 0.5 part~1 part magnesium stearate and 30 parts~91
The auxiliary material of part.The present invention also provides a kind of preparation method of arithoke relieving alcoholism and protecting liver piece, first by the arithoke of non-fiber lignifying
Valve is cleaned, dries, dries, crushed, and obtains cynara scolymus extracts, then by raisin tree seed extract, wolfberry fruit extract, kudzu root extract,
Mannitol, D-sorbite, vitamin C, auxiliary material and the cynara scolymus extracts are uniformly mixed according to aforesaid weight ratio, wet method system
Grain, dry, whole grain, obtain particle；Finally the relieving alcoholism and protecting liver piece semi-finished product are mixed with magnesium stearate, tabletting is to get to most
Whole relieving alcoholism and protecting liver piece.Cynara scolymus extracts are aided with raisin tree seed extract, wolfberry fruit extract and kudzu root extract and are made by the present invention
Tablet, the arithoke relieving alcoholism and protecting liver piece provided have effects that relieving alcoholism and protecting liver, moistening lung nourshing kidney, Shengyang Zhixie etc. are many, solve at present
The problem of tablet artichoke health-care products are less on domestic market, and effect is more single.
Description of the drawings
In order to illustrate more clearly of the technical solution of the application, letter will be made to attached drawing needed in the embodiment below
Singly introduce, it should be apparent that, for those of ordinary skills, without having to pay creative labor,
It can also be obtained according to these attached drawings other attached drawings.
Fig. 1 is a kind of preparation method flow chart of arithoke relieving alcoholism and protecting liver piece provided by the invention.
Specific embodiment
Below in conjunction with the embodiment of the present invention, clear, complete description is carried out to technical scheme, it is clear that institute
The embodiment of description is only the part of the embodiment of the present invention, instead of all the embodiments.Based on the implementation in the present invention
Example, those of ordinary skill in the art's all other embodiments obtained without making creative work, belongs to
The scope of protection of the invention.
The present invention provides a kind of arithoke relieving alcoholism and protecting liver piece, include the component of following weight ratio：
Cynara scolymus extracts：3 parts~30 parts；
Raisin tree seed extract：1 part~10 parts；
Wolfberry fruit extract：1 part~10 parts；
Kudzu root extract：1 part~10 parts；
Further include the component of following weight ratio：
Mannitol：0.5 part~2 parts；
D-sorbite：1 part~2 parts；
Vitamin C：1 part~5 parts；
Magnesium stearate：0.5 part~1 part；
Also include 30 parts~91 parts of auxiliary material.
The weight of the relieving alcoholism and protecting liver piece every is 0.5g~2g.
The present invention provides a kind of arithoke relieving alcoholism and protecting liver pieces, using cynara scolymus extracts as principle active component, are aided with hoveniae semoveniae semen
Extract, wolfberry fruit extract and kudzu root extract, wherein, cynara scolymus extracts for self-control, the present invention to the raisin tree seed extract,
The source and species of wolfberry fruit extract and kudzu root extract are not particularly limited, using trifoliate orange Dulcis well-known to those skilled in the art
Seed extract, wolfberry fruit extract and kudzu root extract.
Arithoke relieving alcoholism and protecting liver piece provided by the invention further includes mannitol, D-sorbite, vitamin C and magnesium stearate, this
Invention is not particularly limited the source of the mannitol, D-sorbite, vitamin C and magnesium stearate and species, using ability
Mannitol, D-sorbite, vitamin C and magnesium stearate known to field technique personnel.
Arithoke relieving alcoholism and protecting liver piece provided by the invention further includes auxiliary material, and the auxiliary material includes filler and adhesive, described
Filler includes starch, Icing Sugar and dextrin, and described adhesive is included in starch slurry, sodium carboxymethylcellulose and hydroxypropyl cellulose
One or more.The present invention is to the starch, Icing Sugar, dextrin, starch slurry, sodium carboxymethylcellulose and hydroxypropyl cellulose
Source and species are not particularly limited, using starch well-known to those skilled in the art, Icing Sugar, dextrin, starch slurry, carboxymethyl
Sodium cellulosate and hydroxypropyl cellulose.
Referring to Fig. 1, the present invention also provides a kind of preparation methods of arithoke relieving alcoholism and protecting liver piece, comprise the following steps：
Step S1：The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
Step S2：By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C,
Auxiliary material and cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein each component is in the shield of relieving the effect of alcohol
Weight ratio in liver slice is as follows：
Cynara scolymus extracts：3 parts~30 parts；
Raisin tree seed extract：1 part~10 parts；
Wolfberry fruit extract：1 part~10 parts；
Kudzu root extract：1 part~10 parts；
Mannitol：0.5 part~2 parts；
D-sorbite：1 part~2 parts；
Vitamin C：1 part~5 parts；
Auxiliary material：30 parts~91 parts；
The auxiliary material includes filler and adhesive；
The filler includes starch, Icing Sugar and dextrin；
Described adhesive includes one or more of starch slurry, sodium carboxymethylcellulose and hydroxypropyl cellulose.
Step S3：The particle is mixed with magnesium stearate, tabletting is to get to final relieving alcoholism and protecting liver piece, wherein, it is described
Weight ratio of the magnesium stearate in the relieving alcoholism and protecting liver piece is 0.5 part~1 part.
The method comprises the steps of firstly, preparing cynara scolymus extracts：The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed,
Obtain cynara scolymus extracts, it is preferred that for the cynara scolymus extracts to be powdered, grain size is less than 100 μm, the present invention to it is described clean,
Dry, drying, the method crushed are not particularly limited, using clean, dry, drying well-known to those skilled in the art and powder
Broken method.
The present invention is aided with raisin tree seed extract, wolfberry fruit extract and pueraria lobata and carries using cynara scolymus extracts as principle active component
Object is taken to prepare arithoke relieving alcoholism and protecting liver piece.Wherein, cynara scolymus extracts are self-control, and the present invention carries the raisin tree seed extract, matrimony vine
The source and species for taking object and kudzu root extract are not particularly limited, and are extracted using hoveniae semoveniae semen well-known to those skilled in the art
Object, wolfberry fruit extract and kudzu root extract.
According to the present invention, by the cynara scolymus extracts, raisin tree seed extract, wolfberry fruit extract and kudzu root extract and sweet dew
Alcohol, D-sorbite, vitamin C and auxiliary material mixing, granulation, dry, sieving, obtain particle, the present invention is to the mannitol, mountain
Pears sugar alcohol, the species of vitamin C and auxiliary material and source are not particularly limited, using sweet dew well-known to those skilled in the art
Alcohol, D-sorbite, vitamin C and auxiliary material；The present invention is not special to the mixing, granulation, dry, sieving method
Limitation, using mixing well-known to those skilled in the art, granulation, dried and screened method, for example, the method for granulating
Any one in wet granulation and dry granulation can be selected.
According to the present invention, the auxiliary material includes filler and adhesive, and the filler includes starch, Icing Sugar and dextrin,
Described adhesive includes one or more of starch slurry, sodium carboxymethylcellulose and hydroxypropyl cellulose.The present invention is to described
Starch, Icing Sugar, dextrin, starch slurry, the source of sodium carboxymethylcellulose and hydroxypropyl cellulose and species are not particularly limited, and are adopted
It is with starch well-known to those skilled in the art, Icing Sugar, dextrin, starch slurry, sodium carboxymethylcellulose and hydroxypropyl cellulose
It can.
According to the present invention, the obtained particles of abovementioned steps S2 are mixed with magnesium stearate, tabletting is relieved the effect of alcohol to get to final
Liver-protecting tablet, the present invention are not particularly limited the source of the magnesium stearate and species, and use is well known to those skilled in the art
Magnesium stearate, the present invention to it is described mixing, tabletting method be not particularly limited, using those skilled in the art institute it is ripe
The mixing known, tabletting method.
For the sake of becoming apparent from, it is described in detail below by following embodiment.
Embodiment 1：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and
The cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein each component is in the relieving alcoholism and protecting liver piece
Weight ratio is as follows：
Cynara scolymus extracts：3 parts；
Raisin tree seed extract：1 part；
Wolfberry fruit extract：1 part；
Kudzu root extract：1 part；
Mannitol：0.5 part；
D-sorbite：1 part；
Vitamin C：1 part；
Starch：71 parts；
Starch slurry：20 parts.
The particle with magnesium stearate is mixed, tabletting, obtain final relieving alcoholism and protecting liver piece, the magnesium stearate is described
Weight ratio in relieving alcoholism and protecting liver piece is 0.5 part.
Embodiment 2：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and
The cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein each component is in the relieving alcoholism and protecting liver piece
Weight ratio is as follows：
Cynara scolymus extracts：30 parts；
Raisin tree seed extract：10 parts；
Wolfberry fruit extract：10 parts；
Kudzu root extract：10 parts；
Mannitol：2 parts；
D-sorbite：2 parts；
Vitamin C：5 parts；
Icing Sugar：20 parts；
Sodium carboxymethylcellulose：10 parts.
The particle with magnesium stearate is mixed, tabletting, obtain final relieving alcoholism and protecting liver piece, the magnesium stearate is described
Weight ratio in relieving alcoholism and protecting liver piece is 1 part.
Embodiment 3：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and
The cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein each component is in the relieving alcoholism and protecting liver piece
Weight ratio is as follows：
Cynara scolymus extracts：10 parts；
Raisin tree seed extract：4 parts；
Wolfberry fruit extract：4 parts；
Kudzu root extract：4 parts；
Mannitol：1 part；
D-sorbite：1 part；
Vitamin C：2 parts；
Dextrin：50 parts；
Hydroxypropyl cellulose：23 parts.
The particle with magnesium stearate is mixed, tabletting, obtain final relieving alcoholism and protecting liver piece, the magnesium stearate is described
Weight ratio in relieving alcoholism and protecting liver piece is 1 part.
Embodiment 4：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and
The cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein each component is in the relieving alcoholism and protecting liver piece
Weight ratio is as follows：
Cynara scolymus extracts：15 parts；
Raisin tree seed extract：5 parts；
Wolfberry fruit extract：5 parts；
Kudzu root extract：5 parts；
Mannitol：1 part；
D-sorbite：1 part；
Vitamin C：2 parts；
Starch：15 parts；
Icing Sugar：10 parts；
Dextrin：10 parts；
Starch slurry：10 parts；
Sodium carboxymethylcellulose：5 parts；
Hydroxypropyl cellulose：5 parts.
The particle with magnesium stearate is mixed, tabletting, obtain final relieving alcoholism and protecting liver piece, the magnesium stearate is described
Weight ratio in relieving alcoholism and protecting liver piece is 1 part.
Embodiment 5：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and
The cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein each component is in the relieving alcoholism and protecting liver piece
Weight ratio is as follows：
Cynara scolymus extracts：20 parts；
Raisin tree seed extract：5 parts；
Wolfberry fruit extract：5 parts；
Kudzu root extract：5 parts；
Mannitol：1 part；
D-sorbite：1 part；
Vitamin C：2 parts；
Starch：20 parts；
Icing Sugar：20 parts；
Starch slurry：10 parts；
Sodium carboxymethylcellulose：10 parts；
The particle with magnesium stearate is mixed, tabletting, obtain final relieving alcoholism and protecting liver piece, the magnesium stearate is described
Weight ratio in relieving alcoholism and protecting liver piece is 1 part.
Embodiment 6：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and
The cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein each component is in the relieving alcoholism and protecting liver piece
Weight ratio is as follows：
Cynara scolymus extracts：25 parts；
Raisin tree seed extract：5 parts；
Wolfberry fruit extract：5 parts；
Kudzu root extract：5 parts；
Mannitol：1 part；
D-sorbite：1 part；
Vitamin C：2 parts；
Starch：20 parts；
Dextrin：20 parts；
Starch slurry：10 parts；
Hydroxypropyl cellulose：5 parts.
The particle with magnesium stearate is mixed, tabletting, obtain final relieving alcoholism and protecting liver piece, the magnesium stearate is described
Weight ratio in relieving alcoholism and protecting liver piece is 1 part.
Embodiment 7：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and
The cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein each component is in the relieving alcoholism and protecting liver piece
Weight ratio is as follows：
Cynara scolymus extracts：25 parts；
Raisin tree seed extract：3 parts；
Wolfberry fruit extract：3 parts；
Kudzu root extract：3 parts；
Mannitol：1 part；
D-sorbite：1 part；
Vitamin C：3 parts；
Icing Sugar：20 parts；
Dextrin：20 parts；
Sodium carboxymethylcellulose：10 parts；
Hydroxypropyl cellulose：10 parts.
The particle with magnesium stearate is mixed, tabletting, obtain final relieving alcoholism and protecting liver piece, the magnesium stearate is described
Weight ratio in relieving alcoholism and protecting liver piece is 1 part.
Embodiment 8：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and
The cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein each component is in the relieving alcoholism and protecting liver piece
Weight ratio is as follows：
Cynara scolymus extracts：30 parts；
Raisin tree seed extract：3 parts；
Wolfberry fruit extract：3 parts；
Kudzu root extract：3 parts；
Mannitol：1.5 part；
D-sorbite：1.5 part；
Vitamin C：2 parts；
Starch：20 parts；
Icing Sugar：10 parts；
Dextrin：10 parts；
Starch slurry：5 parts；
Sodium carboxymethylcellulose：5 parts；
Hydroxypropyl cellulose：5 parts.
The particle with magnesium stearate is mixed, tabletting, obtain final relieving alcoholism and protecting liver piece, the magnesium stearate is described
Weight ratio in relieving alcoholism and protecting liver piece is 1 part.
The above description of the disclosed embodiments, enables professional and technical personnel in the field to realize or use the present invention.It is right
A variety of modifications of these embodiments will be apparent for those skilled in the art, and as defined herein one
As principle can realize in other embodiments without departing from the spirit or scope of the present invention.Therefore, the present invention will
It will not be intended to be limited to the embodiments shown herein, and be to fit to consistent with the principles and novel features disclosed herein
Most wide scope.
Claims (7)
1. a kind of arithoke relieving alcoholism and protecting liver piece, which is characterized in that include the component of following weight ratio：
Cynara scolymus extracts：3 parts~30 parts；
Raisin tree seed extract：1 part~10 parts；
Wolfberry fruit extract：1 part~10 parts；
Kudzu root extract：1 part~10 parts.
2. a kind of arithoke relieving alcoholism and protecting liver piece as described in claim 1, which is characterized in that further include the component of following weight ratio：
Mannitol：0.5 part~2 parts；
D-sorbite：1 part~2 parts；
Vitamin C：1 part~5 parts；
Magnesium stearate：0.5 part~1 part.
3. a kind of arithoke relieving alcoholism and protecting liver piece as described in claim 1, which is characterized in that also include 30 parts~91 parts of auxiliary material；
The auxiliary material includes filler and adhesive；
The filler includes starch, Icing Sugar and dextrin；
Described adhesive includes one or more of starch slurry, sodium carboxymethylcellulose and hydroxypropyl cellulose.
A kind of 4. arithoke relieving alcoholism and protecting liver piece as described in claim 1, which is characterized in that the weight of the relieving alcoholism and protecting liver piece every
For 0.5g~2g.
5. a kind of preparation method of arithoke relieving alcoholism and protecting liver piece, which is characterized in that comprise the following steps：
The arithoke petal of non-fiber lignifying is cleaned, dry, dry, is crushed, obtains cynara scolymus extracts；
By raisin tree seed extract, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and described
Cynara scolymus extracts mixing, granulation, dry, sieving, obtain particle, wherein weight of each component in the relieving alcoholism and protecting liver piece
Than as follows：
Cynara scolymus extracts：3 parts~30 parts；
Raisin tree seed extract：1 part~10 parts；
Wolfberry fruit extract：1 part~10 parts；
Kudzu root extract：1 part~10 parts；
Mannitol：0.5 part~2 parts；
D-sorbite：1 part~2 parts；
Vitamin C：1 part~5 parts；
Auxiliary material：30 parts~91 parts；
The auxiliary material includes filler and adhesive；
The filler includes starch, Icing Sugar and dextrin；
Described adhesive includes one or more of starch slurry, sodium carboxymethylcellulose and hydroxypropyl cellulose；
The particle is mixed with magnesium stearate, tabletting is to get to final relieving alcoholism and protecting liver piece, wherein, the magnesium stearate exists
Weight ratio in the relieving alcoholism and protecting liver piece is 0.5 part~1 part.
6. a kind of preparation method of arithoke relieving alcoholism and protecting liver piece as claimed in claim 5, which is characterized in that it is described will non-fiber it is wooden
In the step of arithoke petal of change is cleaned, dried, drying, crushing, obtain cynara scolymus extracts, the cynara scolymus extracts are powder
Shape, grain size are less than 100 μm.
7. a kind of preparation method of arithoke relieving alcoholism and protecting liver piece as claimed in claim 5, which is characterized in that described to extract hoveniae semoveniae semen
Object, wolfberry fruit extract, kudzu root extract, mannitol, D-sorbite, vitamin C, auxiliary material and cynara scolymus extracts mixing,
In the step of pelletizing, is dry, sieving, obtaining particle, the granulation is one kind in wet granulation and dry granulation.
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| CN114052251A (en) * | 2021-12-23 | 2022-02-18 | 光明乳业股份有限公司 | Liver-protecting and alcohol-dispelling assisting tablet and preparation method thereof |
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