CN108041286A - Amino acid composition and its application, pig feed additive and pannage on piglet muscle growth is promoted - Google Patents

Amino acid composition and its application, pig feed additive and pannage on piglet muscle growth is promoted Download PDF

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Publication number
CN108041286A
CN108041286A CN201711498188.7A CN201711498188A CN108041286A CN 108041286 A CN108041286 A CN 108041286A CN 201711498188 A CN201711498188 A CN 201711498188A CN 108041286 A CN108041286 A CN 108041286A
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CN
China
Prior art keywords
amino acid
acid composition
parts
piglet
pannage
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Pending
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CN201711498188.7A
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Chinese (zh)
Inventor
侯永清
易丹
丁斌鹰
吴涛
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Wuhan Polytechnic University
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Wuhan Polytechnic University
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Priority to CN201711498188.7A priority Critical patent/CN108041286A/en
Publication of CN108041286A publication Critical patent/CN108041286A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/28Silicates, e.g. perlites, zeolites or bentonites
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/60Feeding-stuffs specially adapted for particular animals for weanlings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Birds (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention discloses an amino acid composition and its application, pig feed additive and pannage on piglet muscle growth is promoted, wherein, the pig feed additive amino acid composition and auxiliary material, the amino acid composition include 5 parts of 50 parts of L glutamic acid, 20 parts of L glutamine, glycine 20,10 parts of L arginine and N acetylcysteines.Technical scheme by by L glutamic acid, L glutamine, glycine, L arginine and N acetylcysteines according to 50:20:20:10:5 mixing, are used to prepare the amino acid composition for promoting piglet muscle growth.The amino acid composition has many advantages, such as with strong points, effect stability, definite ingredients, can remarkably promote piglet muscle growth, improves the growth performance of piglet, and significant to improving pig lean meat percentage.

Description

Amino acid composition and its application on piglet muscle growth is promoted, pannage adds Add agent and pannage
Technical field
The present invention relates to field of feed, more particularly to an amino acid composition and its promoting the life of piglet muscle Application, pig feed additive and pannage in length.
Background technology
As people's living standard improves, high quality pork product, particularly lean meat are more popular with consumers.But according to Growth of animal fattens rule, and animal fattening period deposition fat content is more than the deposition of protein.Except cultivating excellent lean meat species Outside kind, too fast measure also is increased weight using limitation pig to increase the lean meat percentage of pig in production.Promote pig flesh using feed addictive Meat is grown and then Ti Gao Of-thin meat rates are also a kind of effective means.However Related product compares shortage.Studies have reported that Chinese herbal medicine Extract can improve the lean meat percentage of pig, but its existence component is complicated, effect is unstable, the problems such as being difficult to standardize, and limits It is applied.
The present invention is based on muscle growth development characteristics, by the further investigation to various functions acidic amino acid, have developed one Kind promotes the amino acid composition of piglet muscle growth, can effectively improve pig muscle protein content and improve the production of animal Performance.
" the Of-thin meat essence " that uses is forbidden by country though muscle growth and Ti Gao Of-thin meat rates can be promoted, its serious change Animal Endocrine hormone levels and have residual harmful to human safety.In addition, Chinese herbal medicine class feed addictive is due to existence component It is complicated, effect is unstable, the problems such as being difficult to standardize, application range is effective.
The content of the invention
The main object of the present invention is to provide an amino acid composition, it is intended to promote piglet muscle growth, improve piglet Growth performance.
To achieve the above object, application of the amino acid composition proposed by the present invention on piglet muscle growth is promoted, In, the amino acid composition includes:
50 parts of Pidolidone;
20 parts of L-Glutamine;
20 parts of glycine;
10 parts of L-arginine;
5 parts of N-acetylcystein.
The present invention also provides a kind of for promoting the amino acid composition of piglet muscle growth, in mass ratio, the amino acid Composition includes:
50 parts of Pidolidone;
20 parts of L-Glutamine;
20 parts of glycine;
10 parts of L-arginine;
5 parts of N-acetylcystein.
The present invention also provides a kind of pig feed additive, the pig feed additive amino acid composition and auxiliary material are described Amino acid composition includes 50 parts of Pidolidone, 20 parts of L-Glutamine, glycine 20,10 parts of L-arginine and N- acetyl half 5 parts of cystine, the auxiliary material are one kind or its combination in defatted rice bran, silica, wheat-middlings and zeolite powder.
Preferably, the amino acid composition accounts for the 30%~80% of total pig feed additive.
Preferably, the amino acid composition accounts for the 45%~55% of total pig feed additive.
The present invention also provides a boar food, the pannage includes amino acid composition, wherein, the amino acid group Closing object includes 50 parts of Pidolidone, 20 parts of L-Glutamine, glycine 20,10 parts of L-arginine and N-acetylcystein 5 Part, the amino acid composition accounts for the 0.5%~1.5% of total pannage weight.
Preferably, the amino acid composition accounts for the 0.75% of total pannage weight.
Technical scheme is by by Pidolidone, L-Glutamine, glycine, L-arginine and N- acetyl half Cystine is according to 50:20:20:10:5 mixing, are used to prepare the amino acid composition for promoting piglet muscle growth.The amino acid Composition has many advantages, such as with strong points, effect stability, definite ingredients, can remarkably promote piglet muscle growth, improve piglet Growth performance, and it is significant to improving pig lean meat percentage.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical solution in the embodiment of the present invention is clearly and completely retouched It states, it is clear that described embodiment is only the part of the embodiment of the present invention, instead of all the embodiments.Based on this hair Embodiment in bright, the every other reality that those of ordinary skill in the art are obtained without creative efforts Example is applied, belongs to the scope of protection of the invention.
It is 50 in mass ratio by Pidolidone, L-Glutamine, glycine, L-arginine and N-acetylcystein: 20:20:10:5 be sufficiently mixed be made the present invention amino acid composition, then according to feed relative 0.5%~ 1.5% adds the amino acid composition.
This example formula is suitable for 7kg~35kg piglets, and application effect is apparent.
Weanling pig is fed with this example additive.The wean consistent with gender of weight that 96 first 21 ages in days disposably wean Piglet is randomly divided into 2 groups, per 6 repetitions (column) of component, per 8, column.The basal diet of each group feeding is consistent.Control group piglet Basal diet in add 0.74% alanine, add 0.75% amino acid in the basal diet of amino acid composition group piglet Composition.Feeding 30 days records pig weight and feed intake, counts the production performance of piglet.Collect piglet blood and muscle (longissimus dorsi muscle, gastrocnemius) sample, is analyzed.As a result it is as follows:
(1) growth performance of piglet
Influence of 1 amino acid composition of table to piglet growth performance
Note:Shoulder mark difference of going together lowercase letter indication difference significantly (P<0.05).Following table is same.
As shown in Table 1, the 22.00% (P of average daily gain of piglet can be improved using the amino acid composition of the present invention< 0.05) 13.69% (P of feed-weight ratio of piglet, is reduced<And 64.27% (P of diarrhea rate 0.05)<0.05).Illustrate the ammonia of the present invention Base acid composition can be effectively improved the production performance and intestinal health of piglet, reduce the generation of disease.
(2) blood parameters
Influence of 2 amino acid composition of table to piglet blood biochemical indicator
Note:Shoulder mark difference of going together lowercase letter indication difference significantly (P<0.05), following table is similary.
As shown in Table 1, the blood total protein content 23.08% of piglet can be improved using the amino acid composition of the present invention (P<And 40.85% (P of blood albumin content 0.05)<0.05) 39.52% (P of blood urea nitrogen (BUN), is reduced<0.05).Illustrate this The amino acid composition of invention can be effectively improved the protein metabolism situation of piglet, promote body protein anabolism.
(3) muscle protein, DNA and RNA
Influence of 3 amino acid composition of table to piglet muscle protein, DNA and RNA
As shown in Table 3, piglet gastrocnemius 17.54% and longissimus dorsi muscle can be improved using the amino acid composition of the present invention 26.87% total protein content (P<0.05), the 11.43% (P of DNA content of gastrocnemius<0.05), the RNA/DNA of longissimus dorsi muscle 23.08% (P of ratio<0.05) and the ratio of TP/DNA reduces by 25.71% (P of blood urea nitrogen (BUN)<0.05).As it can be seen that the present invention Amino acid composition can promote the synthesis of the DNA and protein of muscle, this may promote the gene of muscle with amino acid composition Transcription is related to protein translation.
(4) muscle growth related gene expression
4 amino acid composition of table is to piglet longissimus dorsi muscle amino acid carrier and muscle growth related gene
The influence of mRNA level in-site
Note:MRNA level in-site is detected by quantitative real-time PCR, as a result carries out statistical analysis with 2- Δ Δ Ct methods, right MRNA level in-site, which is set to, according to group is set to 1.
As shown in Table 4, using the present invention amino acid composition can improve piglet longissimus dorsi muscle PepT1 (+47%), b0,+AT (- 115%), CAT-1 (- 55%), MYF5 (- 38%), the mRNA level in-site of MyOG (- 53%) reduce the base of MSTN Because of expression quantity (- 31%), the transhipment of muscle amino acid and small peptide can be promoted by showing the amino acid composition of the present invention, pass through drop The expression of low myostatin (MSTN) promotes muscle cell multiplication and muscle protein synthesis.
The foregoing is merely the preferred embodiment of the present invention, are not intended to limit the scope of the invention, every at this Under the inventive concept of invention, other phases of the equivalent transformation made using present specification or directly/be used in indirectly The technical field of pass is included in the scope of patent protection of the present invention.

Claims (7)

1. application of the amino acid composition on piglet muscle growth is promoted, wherein, the amino acid composition includes:
50 parts of Pidolidone;
20 parts of L-Glutamine;
20 parts of glycine;
10 parts of L-arginine;
5 parts of N-acetylcystein.
A 2. amino acid composition, for promoting piglet muscle growth, which is characterized in that in mass ratio, including:
50 parts of Pidolidone;
20 parts of L-Glutamine;
20 parts of glycine;
10 parts of L-arginine;
5 parts of N-acetylcystein.
3. a kind of pig feed additive, which is characterized in that including amino acid composition as claimed in claim 2 and auxiliary material, institute Auxiliary material is stated as one kind in defatted rice bran, silica, wheat-middlings and zeolite powder or its combination.
4. pig feed additive as claimed in claim 3, which is characterized in that the amino acid composition accounts for total pannage addition The 30%~80% of agent.
5. pig feed additive as claimed in claim 4, which is characterized in that the amino acid composition accounts for total pannage addition The 45%~55% of agent.
A 6. boar food, which is characterized in that including amino acid composition as claimed in claim 2, wherein, the amino acid Composition accounts for the 0.5%~1.5% of total pannage weight.
7. pannage as claimed in claim 6, which is characterized in that the amino acid composition accounts for total pannage weight 0.75%.
CN201711498188.7A 2017-12-29 2017-12-29 Amino acid composition and its application, pig feed additive and pannage on piglet muscle growth is promoted Pending CN108041286A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110582207A (en) * 2018-12-18 2019-12-17 黄华成 Application of glutamine derivative in preparation of animal feed additive
CN111317070A (en) * 2020-04-26 2020-06-23 浙江省农业科学院 Feed additive for improving meat quality of fattening pigs and application

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104351478A (en) * 2014-11-25 2015-02-18 武汉轻工大学 Composite functional amino acid feed additive and application
CN104431644A (en) * 2015-01-13 2015-03-25 四川农业大学 Amino acid additive capable of improving growth capacity and intestinal health of weaned pig

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104351478A (en) * 2014-11-25 2015-02-18 武汉轻工大学 Composite functional amino acid feed additive and application
CN104431644A (en) * 2015-01-13 2015-03-25 四川农业大学 Amino acid additive capable of improving growth capacity and intestinal health of weaned pig

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
郑建仙编著: "《功能性食品典型配方和关键技术》", 30 April 2005, 科学技术文献出版社 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110582207A (en) * 2018-12-18 2019-12-17 黄华成 Application of glutamine derivative in preparation of animal feed additive
WO2020124351A1 (en) * 2018-12-18 2020-06-25 黄华成 Application of glutamine derivative in preparation of animal feed additive
CN110582207B (en) * 2018-12-18 2022-11-11 广州英赛特生物技术有限公司 Application of glutamine derivative in preparation of animal feed additive
US11964929B2 (en) 2018-12-18 2024-04-23 Wisorig Technologies Pte. Limited Application of glutamine derivative in preparation of animal feed additive
CN111317070A (en) * 2020-04-26 2020-06-23 浙江省农业科学院 Feed additive for improving meat quality of fattening pigs and application
CN111317070B (en) * 2020-04-26 2022-12-23 浙江省农业科学院 Feed additive for improving meat quality of fattening pigs and application

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Application publication date: 20180518

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