CN108037304A - The sample adding device and its loading methods of Full-automatic chemiluminescence analyzer - Google Patents
The sample adding device and its loading methods of Full-automatic chemiluminescence analyzer Download PDFInfo
- Publication number
- CN108037304A CN108037304A CN201711491909.1A CN201711491909A CN108037304A CN 108037304 A CN108037304 A CN 108037304A CN 201711491909 A CN201711491909 A CN 201711491909A CN 108037304 A CN108037304 A CN 108037304A
- Authority
- CN
- China
- Prior art keywords
- sample
- area
- reagent
- needle
- filling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000011068 loading method Methods 0.000 title claims abstract description 15
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 108
- 238000005070 sampling Methods 0.000 claims abstract description 58
- 238000004140 cleaning Methods 0.000 claims abstract description 31
- 230000001360 synchronised effect Effects 0.000 claims description 39
- 239000002184 metal Substances 0.000 claims description 11
- 230000007246 mechanism Effects 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
- 230000004044 response Effects 0.000 claims description 4
- 238000012360 testing method Methods 0.000 claims description 3
- 238000002474 experimental method Methods 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000000523 sample Substances 0.000 description 131
- 230000005540 biological transmission Effects 0.000 description 9
- 238000012864 cross contamination Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 239000004065 semiconductor Substances 0.000 description 2
- 239000011324 bead Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000005429 filling process Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention provides a kind of sample adding device and its loading methods of Full-automatic chemiluminescence analyzer, including sampling needle system, reagent needle system and the sample area set gradually from left to right, fill area and reagent area, the sampling needle system and reagent needle system are fixed on same root cross slide way, it is described that the reaction cup area vertical with filling area is set between reagent area and sample area, between the sample area and filling area, needle cleaning device is set respectively between reagent area and filling area, the sample area, fill area, reagent area and the sampling position of two needle cleaning devices are on the same line, syringe needle is sampled by sample area and the sampling position in filling area, reagent syringe needle is by reagent area and the sampling position in filling area.The sample adding device and its loading methods of Full-automatic chemiluminescence analyzer described in the invention, sample bits, filling position, groove and cleaning area are in same straight line, lifting filling speed;Sample bits and filling position are fixed, and the probability for mistake occur reduces.
Description
Technical field
The invention belongs to medical instruments field, sample adding device more particularly, to Full-automatic chemiluminescence analyzer and
Its loading methods.
Background technology
Chemiluminescent analyzer has the characteristics that detection speed is fast, the range of linearity is wide, has a wide range of application, and has been widely used
In in clinical immunization diagnosis.Under normal conditions, in chemiluminescence analysis analyzer, flow cell, sample disk, reagent disc are generally included
With the component such as sampler, sampler is used to draw the materials such as magnetic bead in the sample and reagent disc in sampling dish, R1, R2,
And be mixed, mixture is sent into flow cell and carries out chemiluminescence reaction.
Existing sampler is usually can be along the structure of tri- directions of X, Y and Z linear motion, during sampling, sample point
The region that sampler covers in above three direction can be distributed in, you can when realizing the sampling of optional position, but sampling
Need the coordinate control sampler for calculating tri- directions of X, Y, Z to complete sampling, cause the speed of sampling slower, if sampling coordinate
When there is deviation, it is impossible to realize accurate sampling, the precision of the sampler is relatively low.
Sampling probe is placed in sampling probe row by existing sampler along X, Y both direction, sampling position, reagent position and reaction cup
Into on the same straight line in direction, cleaning area is set between reaction cup and reagent position, but after sample-adding or reagent, syringe needle cleaning
It is not in place, cross contamination will be caused, cause analysis result inaccurate, due to sampling and taking reagent to carry out respectively, cause to prepare anti-
The speed of cup solution is answered to decline.
In view of above-mentioned sampler there are the defects of, it would be highly desirable to a kind of higher sampling precision, speed are provided and avoid handing over
Pitch the sampler of pollution.
The content of the invention
In view of this, the invention is directed to sample adding device and its sample-adding side of Full-automatic chemiluminescence analyzer
Method, to solve the problems, such as that chemiluminescent analyzer sample-adding reagent adding process efficiency is low, slow-footed, the another object of the invention
It is that cross contamination easily occurs when solving the problems, such as to prepare reaction solution.
To reach above-mentioned purpose, what the technical solution of the invention was realized in:
The sample adding device and its loading methods of Full-automatic chemiluminescence analyzer, including sampling needle system, reagent needle system
Sample area, filling area and the reagent area set gradually from left to right, the sampling needle system and reagent needle system are fixed on together
It is described that the reaction cup area vertical with filling area, the sample area are set between reagent area and sample area on a piece cross slide way
Between filling area, needle cleaning device, the sample area, filling area, reagent area are set respectively between reagent area and filling area
With the sampling positions of two needle cleaning devices on the same line, sampling needle system is by sample area, needle cleaning device and filling
The sampling position in area, reagent needle system is by reagent area, needle cleaning device and the sampling position for filling area.
Further, the sample area sets several parallel sample slots, and described sample slot one end sets sample to indicate
Lamp, sample slot is interior to set the sample rack for being used for holding sample tube, the nearest sample slot of the distance samples needle cleaning device
It is set to sample bits.
Further, side of the sample area away from sample indicator light sets sample trolley, and the sample trolley includes
Telescopic device, translating device, sample rack storage groove and sample rack crawl hook, one end of the sample rack crawl hook are placed in sample rack
In storage groove, specimen holder sets groove close to one end of sample trolley, and sample rack crawl hook can enter groove dragging sample rack, sample
The other end of this crawl hook is fixed on telescopic device, and sample rack storage groove bottom is fixed on the translating device of sample trolley
On.
Further, the reaction cup area includes several reaction cup indicator lights, reaction cup storehouse and interlink frame, the reaction
Cup indicator light is evenly spaced on same straight line in the one end in reaction cup storehouse and close to sample slot side, and the interlink frame is close to anti-
Answer cup indicator light side that the metal derby with circular hole is set, the hole of placing response cup, the interlink frame are set away from metal Block direction
It is placed in reaction cup storehouse, the reaction cup storehouse is fixed on translating device and can move left and right in the horizontal plane.
Further, the filling area includes interlink frame placing groove, electromagnet, telescopic device, and electromagnet passes through telescopic rod
It is fixed on telescopic device, electromagnet can be inserted into the circular hole of interlink frame side metal derby, and the telescopic device will by electromagnet
Reaction cup in interlink frame is moved to filling position from reaction cup storehouse.
Further, the sampling needle system and reagent needle system include syringe needle, lifting gear and translating device, institute respectively
State syringe needle to be fixed on lifting gear, the lifting gear side is fixed on cross slide way, at the top of the lifting gear is passed through
Synchronous fixed block is fixed on translating device, samples the translating device of needle system and reagent needle system respectively positioned at cross slide way
Upper and lower both sides.
Further, the screw slider mechanism that the lifting gear is vertically arranged, the screw slider mechanism include the
Two motor support plates, the second motor and feed screw nut, the translating device and telescopic device include the first motor, the first motor branch
Fagging, driving wheel, driven wheel and conveyer belt, conveyer belt are wound on driving wheel and driven wheel.
Further, the reagent area includes shell, apparatus for cold air circulation, radiator, rotary positioning apparatus and synchronization
Rotating disk, sets synchronous rotary disk in the shell, and the bracket of fixed placement reagent test tube, described same on the synchronous rotary disk
Step rotating disk is connected with rotary positioning apparatus, and the synchronous rotary disk lower part sets apparatus for cold air circulation, the circulating cold air dress
Put lower part and radiator is set.
Further, the shell sets upper cover with holes, the line in all hole centers of circle straight line parallel with cross slide way
On, the synchronous rotary disk is disposed radially some group reagent positions, per group reagent position by rotate by a certain angle can with shell
Hole correspond to.
The technical solution adopted in the present invention further includes the sample adding device of the above-mentioned Full-automatic chemiluminescence analyzer of utilization
Loading methods, the loading methods specifically include following steps:
A. sample to be tested is loaded to sample slot, the interlink frame in reaction cup storehouse places new reaction cup, by filling area
The interlink frame in reaction cup area is moved to filling area by telescopic device, and determines filling position, and reagent area adds the reagent of test;
B. reagent needle aspirate reagent, is moved to filling position by translating device, reagent is instilled in reaction cup, reagent pin
System is moved to needle cleaning device and reagent syringe needle is cleaned, and reagent needle system is reset to above reagent area;
C. sample trolley drags sample slot to sample bits, samples needle aspirate sample, filling is moved to by translating device
Position, sample is instilled in reaction cup, and sampling needle system is moved to needle cleaning device and sampling syringe needle is cleaned, sampling needle system
System is reset to above sample area;
When d. needing to carry out new analysis experiment, the reaction cup that the telescopic device in area drives interlink frame more to renew, rotation are filled
Positioner drives synchronous rotary disk to turn to new reagent position, and sample trolley dragging sample slot makes sample to be tested to sample bits;
E. b-c is repeated, sample-adding terminates.
Relative to the prior art, the sample adding device and its sample-adding of the Full-automatic chemiluminescence analyzer described in the invention
Method has the advantage that:
(1) sample adding device and its loading methods of the Full-automatic chemiluminescence analyzer described in the invention, sampling needle
System is fixed on same guide rail with reagent needle system, and installation space is greatly saved, is conducive to the miniaturization of equipment;Sampling
Position, filling position, groove, sampling needle cleaning area and reagent pin cleaning area are in same straight line, the mobile route of sampling needle and reagent pin
It is most short, the speed lifting of filling.
(2) sample adding device and its loading methods of the Full-automatic chemiluminescence analyzer described in the invention, sample area
Equipped with sample bits, the transverse direction for filling position is fixed, and fixes sample bits and the distance of filling position, can occur to avoid sampling needle system
Programmed logic mistake;Fill position at the same time and the relative position of reagent disc groove is fixed, will also reduce reagent pin and walk the probability that misplaces, by
It is poor in sampling needle sample-adding and reagent pin reagent adding existence time, shorten the filling time.
(3) sample adding device and its loading methods of the Full-automatic chemiluminescence analyzer described in the invention, is sampling
Sampling needle cleaning area, groove and filling interdigit setting reagent pin cleaning area are inserted between position and filling position, after syringe needle fills,
It can quickly be cleaned, prepare for filling next time, avoid the situation of cross contamination.
Brief description of the drawings
The attached drawing for forming the part of the invention is used for providing further understanding the invention, present invention wound
The schematic description and description made is used to explain the invention, does not form the improper restriction to the invention.
In attached drawing:
Fig. 1 is the structure diagram of the invention embodiment;
Fig. 2 is the schematic diagram of the invention reagent area and sample area
Fig. 3 is the schematic diagram that the invention samples needle system and reagent needle system;
Fig. 4 is the top view of the invention reagent area;
Fig. 5 is the sectional view in the invention reagent area N-N directions;
Fig. 6 is the sectional view in the invention reagent area P-P directions;
Description of reference numerals:
1st, needle system is sampled;11st, syringe needle is sampled;
2nd, reagent needle system;21st, reagent syringe needle;
3rd, translating device;31st, driving wheel;32nd, driven wheel;33rd, conveyer belt;34th, the first motor support plate;35th, the first electricity
Machine;39th, telescopic device;
4th, lifting gear;41st, the second motor support plate;42nd, the second motor;43rd, feed screw nut;
5th, sample area;51st, sample slot;52nd, sample rack;53rd, sample indicator light;54th, sample bits;
6th, sampling small car;61st, sample rack storage groove;62nd, sample rack crawl hook;
7th, reaction cup area;71st, reaction cup storehouse;72nd, interlink frame;73rd, reaction cup indicator light;
8th, area is filled;81st, interlink frame placing groove;82nd, telescopic rod;
9th, reagent area;91st, shell;92nd, installing plate;93rd, synchronous rotary disk;94th, apparatus for cold air circulation;95th, radiator;
96th, rotary positioning apparatus;961st, synchronizing wheel;962nd, position rotating axis;963rd, clutch shaft bearing;964th, synchronous rotary gear;965、
Second bearing;966th, 3rd bearing;967th, synchronous rotary angle catch;97th, bracket;98th, bar code scanner;
10th, needle cleaning device;101st, it is responsible for;102nd, looped pipeline;103rd, support plate;104th, pin holes;105th, waste liquid interface.
Embodiment
It should be noted that in the case where there is no conflict, the feature in embodiment and embodiment in the invention can
To be mutually combined.
In the description of the invention, it is to be understood that term " " center ", " longitudinal direction ", " transverse direction ", " on ", " under ",
The orientation or position relationship of the instruction such as "front", "rear", "left", "right", " vertical ", " level ", " top ", " bottom ", " interior ", " outer " are
Based on orientation shown in the drawings or position relationship, it is for only for ease of description the invention and simplifies description, rather than instruction
Or imply that signified device or element must have specific orientation, with specific azimuth configuration and operation, therefore be not understood that
For the limitation to the invention.In addition, term " first ", " second " etc. are only used for description purpose, and it is not intended that instruction
Or imply relative importance or the implicit quantity for indicating indicated technical characteristic.Thus, " first ", " second " etc. are defined
Feature can express or implicitly include one or more this feature.In the description of the invention, unless separately
It is described, " multiple " are meant that two or more.
, it is necessary to which explanation, unless otherwise clearly defined and limited, term " are pacified in the description of the invention
Dress ", " connected ", " connection " should be interpreted broadly, for example, it may be fixedly connected or be detachably connected, or integratedly
Connection;Can mechanically connect or be electrically connected;It can be directly connected, can also be indirectly connected by intermediary,
It can be the connection inside two elements.For the ordinary skill in the art, on being understood by concrete condition
State concrete meaning of the term in the invention.
The present invention will be described in detail below with reference to the accompanying drawings and in conjunction with the embodiments creates.
As shown in Figs. 1-3, the sample adding device and its loading methods of Full-automatic chemiluminescence analyzer, including sampling needle system
1st, reagent needle system 2 and the sample area 5, filling area 8 and the reagent area 9 that set gradually from left to right, sample needle system 1 and reagent pin
System 2 is fixed on same root cross slide way, and sample needle system 1 and reagent needle system 2 includes syringe needle, 4 and of lifting gear respectively
Translating device 3, the screw slider mechanism that lifting gear 4 is vertically arranged, including the second motor support frame 41, the second motor 42
With feed screw nut 43, translating device 3 drives belt transmission agency to realize by motor, and belt transmission agency is by the first motor 35, the
One motor support plate 34, driving wheel 31, driven wheel 32 and conveyer belt 33 form, and driving wheel 31 and driven wheel 32 are distributed in and laterally lead
Rail homonymy, conveyer belt 33 are wound on driving wheel 31 and driven wheel 32, and the first motor 35 driving driving wheel 31 is simultaneously fixed on the first electricity
In machine support plate 34.The shaft of second motor 42 is solid by feed screw nut 43 through sampling syringe needle 11 or 21 fixed seat of reagent syringe needle
Fixed, the other end of sampling 21 fixed seat of syringe needle 11 or reagent syringe needle is fixed on sliding block, and sliding block is fixed on upright guide rail, vertically
Guide rail is fixed on the second motor support frame 41, and 41 reverse side of the second motor support plate is fixed on cross slide way by sliding block, the
The top of two motor support plate 41 is connected by synchronous fixed block with the conveyer belt 33 of translating device 3, and cross slide way is fixed on first
In motor support plate 34, the translating device 3 of sampling needle system 1 and reagent needle system 2 is located at the both sides up and down of cross slide way respectively,
The length when length of second motor support plate 41 is than sampling needle system 1 and reagent needle system 2 apart from maximum is long.
Sample area 5 sets several parallel sample slots 51, and 51 one end of sample slot sets sample indicator light 53, sample slot
The sample rack 52 for being used for holding sample tube is set in 51, and side of the specimen holder away from sample indicator light 53 sets section L-type
Groove 92.Side of the sample area 5 away from sample indicator light 53 sets sample trolley, and sample trolley includes telescopic device 39, translation
Device 3, sample rack storage groove 61 and sample rack crawl hook 62, telescopic device 39 and translating device 3 are real by belt transmission agency
Existing, belt transmission agency is made of the first motor 35, the first motor support plate 34, driving wheel 31, driven wheel 32 and conveyer belt 33,
Conveyer belt 33 is wound on driving wheel 31 and driven wheel 32, and the first motor 35 driving driving wheel 31 is simultaneously fixed on the first motor support plate
On 34.The conveyer belt 33 of translating device 3 is vertical with sample slot 51, and the conveyer belt 33 of telescopic device 39 is parallel with sample slot 51, sample
One end of this crawl hook 62 is placed in sample rack storage groove 61 and can enter the L-type groove of sample slot 51, sample rack crawl hook
62 other end is fixed on the conveyer belt 33 of telescopic device 39 by synchronous fixed block, and sample rack crawl hook 62 passes through sliding block
It is fixed on guide rail, guide rail is fixed in the first motor support plate 34 of telescopic device 39, and 61 side of sample rack storage groove is with stretching
First motor support plate 34 of compression apparatus 39 is fixedly connected, and 61 bottom of sample rack storage groove is fixed on guide rail by sliding block, is led
Rail is fixed in the first motor support plate 34 of translating device 3, and 61 bottom of sample rack storage groove sets synchronous fixed by sliding block
Block, the conveyer belt 33 of synchronous fixed block and translating device 3 are fixed, and the conveyer belt 33 of telescopic device 39 is parallel with sample slot 51, sample
This storage groove 61 is identical with 51 structure of sample slot, is arranged in parallel in the same plane.
When shifting sample rack 52 using sample trolley, translating device 3 moves the sample rack storage groove 61 on sample trolley
To sample slot 51 to be transferred, sample rack storage groove 61 drives sample with respect to sample slot 51 away from sample bits 54, telescopic device 39
Frame captures hook 62 and enters from the slightly wider position of the L-type groove of sample rack 52, and translating device 3 works as sample to 54 directional trim of sample bits
When this groove 51 and sample rack storage groove 61 are aligned, show sample rack crawl hook 62 and 52 clamping of sample rack, sample rack crawl hook 62
Sample rack 52 is slowly taken out from sample slot 51, and is dragged in sample rack storage groove 61, mobile translating device 3 deposits sample rack
The alignment of groove 61 sample bits 54 are put to be dragged in.
As Figure 4-Figure 6, reagent area 9 include shell 91, installing plate 92, bar code scanner 98, apparatus for cold air circulation 94,
Radiator 95, rotary positioning apparatus 96, bracket 97 and synchronous rotary disk 93, set upper cover with holes on shell 91, hole is used for
Expose reagent position, insulating layer is set on the inside of upper cover, insulating layer does not cover hole, and 91 bottom surface of shell is fixed on installing plate 92, shell
91 inside set metallic plate, and insulating foam layer is set between 91 inner wall of metallic plate and shell, the closest shell with filling area
91 side walls set opening, and sidewall opening connection accommodates the housing of bar code scanner 98, and the housing away from shell sets flow-disturbing wind
Fan, the inside of shell 91 set circular synchronous rotary disk 93, and synchronous rotary disk 93 is designed using porous hollow out, synchronous rotary disk
93 outwards set some group reagent positions along radius, and reagent is fixed on the reagent position of synchronous rotary disk 93 by bracket 97, with bar code
Close 97 side of bracket of scanning means 98 sets bar code scan position, it is preferred that reagent position includes 20 groups, per group reagent position most
3 kinds of reagents can be stored more, and reagent position can be corresponding with the hole on shell 91 by rotating by a certain angle, 91 bottom surface of shell and peace
Loading board 92 is respectively provided with refrigeration window, and apparatus for cold air circulation 94 is set below synchronous rotary disk 93, and apparatus for cold air circulation 94 is from upper
Set gradually under including spoiler, cold scattering piece and semiconductor chilling plate, cold scattering piece is fixed on installing plate 92, semiconductor system
Cold lower part is equipped with radiator 95, and radiator 95 sets heat sink and radiator fan from top to bottom, and heat sink is fixed on peace
In loading board 92.Synchronous rotary disk 93 is fixed on rotary positioning apparatus 96, and rotary positioning apparatus 96 includes synchronizing wheel 961, positioning
Rotation axis 962, clutch shaft bearing 963, synchronous rotary gear 964, second bearing 965,3rd bearing 966 and bearing supporting frame, together
Step wheel 961 is fixed on synchronous rotary disk 93, and 962 one end of position rotating axis is fixed with synchronizing wheel 961, and position rotating axis 962 is logical
Cross clutch shaft bearing 963 to be fixed on installing plate 92,963 lower end of clutch shaft bearing and synchronous rotary gear 964 are ratcheting, synchronous rotary
Gear 964 is connected by synchronous belt with motor, and there are the loop configuration of protrusion, loop configuration difference in 964 lower end of synchronous rotary gear
It is connected with second bearing 965 and 3rd bearing 966, by bearing gland fixing seal on bearing base, bearing base is fixed
On bearing supporting frame, position rotating axis 962 is through bearing supporting frame connection synchronous rotary angle catch 967, synchronous rotary angle
Spend 967 lower end of catch and photoelectric sensor is set, the accurate measurement of each position is carried out by photoelectric sensor.
Reaction cup area 7 is set between reagent area 9 and sample area 5, and reaction cup area 7 includes several reaction cup indicator lights
73rd, reaction cup storehouse 71, interlink frame 72 and translating device 3, reaction cup indicator light 73 is in the one end in reaction cup storehouse 71 and close to sample
51 side of groove is evenly spaced on same straight line, and interlink frame 72 sets the metal with circular hole close to 73 side of reaction cup indicator light
Block, the groove of placing response cup is set away from metal Block direction, and interlink frame 72 is placed in reaction cup storehouse 71, and translating device 3 is by motor
Belt transmission agency is driven to realize, belt transmission agency is by the first motor 35, the first motor support plate 34, driving wheel 31, driven
Wheel 32 and conveyer belt 33 form, and the bottom in reaction cup storehouse 71 is fixed on guide rail by sliding block, and guide rail is fixed on the first motor branch
On fagging 34, reaction cup storehouse 71 sets synchronous fixed block at sliding block, makes the conveyer belt 33 of reaction cup storehouse 71 and translating device 3
Synchronized links, the transmission direction of conveyer belt 33 is vertical with the opening direction in reaction cup storehouse 71, enables reaction cup storehouse 71 in horizontal plane
Inside move left and right.
Area 8 is filled in the inner side of sample area 5, reaction cup area 7 and reagent area 9, including interlink frame placing groove 81, electromagnet,
Telescopic rod 82, telescopic device 39 and guide rail, the structure of interlink frame placing groove 81 is identical with the structure in reaction cup storehouse 71, and interlink frame is put
Put groove 81 to be aligned with one of reaction cup storehouse 71, telescopic device 39 drives belt transmission agency to realize by motor, belt transmission
Mechanism is made of the first motor 35, the first motor support plate 34, driving wheel 31, driven wheel 32 and conveyer belt 33, telescopic device 39
Conveyer belt 33 it is parallel with the moving direction in reaction cup storehouse 71, electromagnet is fixed on telescopic rod 82, the vertical interlink frame of electromagnet
The bottom surface of placing groove 81, electromagnet can be inserted into the circular hole of 72 side metal derby of interlink frame, and telescopic rod 82 is fixed on by sliding block leads
On rail, the top of telescopic rod 82 is fixed on the conveyer belt 33 of telescopic device 39 by synchronous fixed block, and the guide rail in filling area 8 is crossed over
Reaction cup area 7 is set, and when the interlink frame 72 in reaction cup storehouse 71 needs to be moved to filling area 8, electromagnet drives in telescopic device 39
The metal derby position of 7 interlink frame 72 of reaction cup area is moved to, adjustable telescopic rod 82 makes the circular hole of electromagnet insertion metal derby, stretches
Compression apparatus 39 is moved with motor magnet and interlink frame 72 to interlink frame placing groove 81, the reaction cup in interlink frame 72 is moved to company
The filling position of ring stand placing groove 81.
Needle cleaning device 10, sample are set respectively between sample area 5 and filling area 8, between reagent area 9 and filling area 8
Area 5, filling area 8,9 and two needle cleaning device 10 of reagent area sampling position on the same line, sampling syringe needle 11 system is passed through
Sample area 5, needle cleaning device 10 and the sampling position for filling area 8,21 system of reagent syringe needle is by reagent area 9, syringe needle cleaning dress
The sampling position of 10 and filling area 8 is put, the nearest sample slot 51 in distance samples pin cleaning area is set to sample bits 54.
The operation principle of the device:
During normal work, the small handlebar sample rack 52 of sample is dragged to sample bits 54, samples 1 transverse shifting of needle system, sampling
Syringe needle 11 is inserted into specimen bottle by lifting gear 4 and draws sample, and reaction cup storehouse 71 is laterally moved under the drive of translating device
It is dynamic, filling area 8 is corresponded to, interlink frame 72 is dragged to filling area 8 by filling trolley, makes reaction cup positioned at filling position, sampling needle system
System 1 moves laterally to filling position, and sampling syringe needle 11 instills sample in reaction cup, then samples syringe needle 11 and returns to syringe needle cleaning dress
Put 10;At the same time, reagent needle system 2 moves laterally to the reagent position of reagent area 9, is inserted reagent syringe needle 21 by lifting gear 4
Enter in reagent bottle, draw reagent, rise reagent syringe needle 21 and move laterally to filling position, be added dropwise in reaction cup, reagent syringe needle
22 clean to needle cleaning device 10, so far complete a filling process.The device feed rate is fast, accuracy is high, can keep away
Exempt from the generation of cross contamination.
The foregoing is merely the preferred embodiment of the invention, is not intended to limit the invention creation, all at this
Within the spirit and principle of innovation and creation, any modification, equivalent replacement, improvement and so on, should be included in the invention
Protection domain within.
Claims (10)
1. the sample adding device of Full-automatic chemiluminescence analyzer, it is characterised in that:Including sampling needle system (1), reagent needle system
(2) and from left to right the sample area (5) that sets gradually, filling area (8) and reagent area (9), it is described to sample needle system (1) and reagent
Needle system (2) is fixed on same root cross slide way, described to be set between reagent area (9) and sample area (5) and filling area (8)
Vertical reaction cup area (7), sets respectively between the sample area (5) and filling area (8), between reagent area (9) and filling area (8)
Needle cleaning device (10) is put, the sample area (5), fill taking for area (8), reagent area (9) and two needle cleaning devices (10)
Sample position on the same line, samples sampling of the syringe needle (11) by sample area (5), needle cleaning device (10) and filling area (8)
Position, reagent syringe needle (22) by reagent area (9), needle cleaning device (10) and filling area (8) sampling position.
2. the sample adding device of Full-automatic chemiluminescence analyzer according to claim 1, it is characterised in that:The sample area
(5) several parallel sample slots (51) are set, and described sample slot (51) one end sets sample indicator light (53), sample slot (51)
It is interior that the sample rack (52) for being used for holding sample tube, the nearest sample slot of the distance samples needle cleaning device (10) are set
(51) sample bits (54) are set to.
3. the sample adding device of Full-automatic chemiluminescence analyzer according to claim 1, it is characterised in that:The sample area
(5) side away from sample indicator light (53) sets sample trolley, and the sample trolley includes telescopic device (39), translating device
(3), sample rack storage groove (61) and sample rack crawl hook (62), one end of the sample rack crawl hook (62) are placed in sample rack and deposit
Put in groove (61), specimen holder (52) sets groove close to one end of sample trolley, and sample rack crawl hook (62) can be dragged into groove
Dynamic sample rack (52), the other end of sample rack crawl hook (62) are fixed on telescopic device (39), sample rack holding tank (61) bottom
Face is fixed on the translating device (3) of sample trolley.
4. the sample adding device of Full-automatic chemiluminescence analyzer according to claim 1, it is characterised in that:The reaction cup
Area (7) includes several reaction cup indicator lights (73), reaction cup storehouse (71) and interlink frame (72), the reaction cup indicator light (73)
It is evenly spaced in the one end of reaction cup storehouse (71) and close to sample slot (51) side on same straight line, the interlink frame (72) is leaned on
Proximal response cup indicator light (73) side sets the metal derby with circular hole, and the hole of placing response cup, institute are set away from metal Block direction
State interlink frame (72) to be placed in reaction cup storehouse (71), the reaction cup storehouse (71) is fixed on can be in horizontal plane on translating device (3)
Inside move left and right.
5. the sample adding device of Full-automatic chemiluminescence analyzer according to claim 1, it is characterised in that:The filling area
(8) interlink frame placing groove (81), electromagnet, telescopic device (39) are included, electromagnet is fixed on flexible dress by telescopic rod (82)
Put on (39), electromagnet can be inserted into the circular hole of interlink frame (72) side metal derby, and the telescopic device (39) will by electromagnet
Reaction cup in interlink frame (72) is moved to filling position from reaction cup storehouse (71).
6. the sample adding device of Full-automatic chemiluminescence analyzer according to claim 1, it is characterised in that:The sampling needle
System (1) and reagent needle system (2) include syringe needle, lifting gear (4) and translating device (3), the syringe needle and are fixed on liter respectively
On falling unit (4), lifting gear (4) side is fixed on cross slide way, by synchronous solid at the top of the lifting gear (4)
Determine block to be fixed on translating device (3), the translating device (3) of sampling needle system (1) and reagent needle system (2) is respectively positioned at laterally
The both sides up and down of guide rail.
7. according to the sample adding device of claim 3-6 any one of them Full-automatic chemiluminescence analyzers, it is characterised in that:Institute
State the screw slider mechanism that lifting gear (4) is vertically arranged, the screw slider mechanism include the second motor support plate (41),
Second motor (42) and feed screw nut (43), the translating device (3) and telescopic device (39) include the first motor (35), first
Motor support plate (34), driving wheel (31), driven wheel (32) and conveyer belt (33), conveyer belt (33) be wound on driving wheel (31) and from
On driving wheel (32).
8. according to the sample adding device of claim 1 any one of them Full-automatic chemiluminescence analyzer, it is characterised in that:It is described
Reagent area (9) includes shell (91), apparatus for cold air circulation (94), radiator (95), rotary positioning apparatus (96) and synchronous rotation
Turntable (93), sets synchronous rotary disk (93) in the shell (91), fixed placement reagent examination on the synchronous rotary disk (93)
The bracket (97) of pipe, the synchronous rotary disk (93) are connected with rotary positioning apparatus (96), synchronous rotary disk (93) lower part
Apparatus for cold air circulation (94) is set, and apparatus for cold air circulation (94) lower part sets radiator (95).
9. the sample adding device of Full-automatic chemiluminescence analyzer according to claim 8, it is characterised in that:The shell
(91) upper cover with holes is set, on the line in all hole centers of circle straight line parallel with cross slide way, the synchronous rotary disk (93)
Some group reagent positions are disposed radially, can be corresponding with the hole on shell (91) by rotating by a certain angle per group reagent position.
10. a kind of loading methods of the sample adding device of Full-automatic chemiluminescence analyzer using described in claim 1, its feature
It is that this method comprises the following steps:
A. sample to be tested is loaded to sample slot (51), the interlink frame (72) in reaction cup storehouse (71) places new reaction cup, passes through
The interlink frame (72) of reaction cup area (7) is moved to filling area (8) by the telescopic device (39) for filling area (8), and determines filling position,
Reagent area (9) adds the reagent of test;
B. reagent syringe needle (21) draws reagent, is moved to filling position by translating device (3), reagent is instilled in reaction cup, examination
Agent needle system (2) is moved to needle cleaning device (10) and reagent syringe needle (21) is cleaned, and reagent needle system (2) is reset to examination
Above agent area (9);
C. sample trolley dragging sample slot (51) to sample bits (54), sampling syringe needle (11) are drawn sample, are passed through translating device (3)
Filling position is moved to, sample is instilled in reaction cup, sampling needle system (1) is moved to needle cleaning device (10) to sampling syringe needle
(11) cleaned, sampling needle system (1) is reset to above sample area (5);
When d. needing to carry out new analysis experiment, the telescopic device (39) of filling area (8) drives the reaction that interlink frame (72) more renews
Cup, rotary positioning apparatus (96) drive synchronous rotary disk (93) to turn to new reagent position, sample trolley dragging sample slot (51)
Make sample to be tested to sample bits (54);
E. b-c is repeated, sample-adding terminates.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711491909.1A CN108037304A (en) | 2017-12-30 | 2017-12-30 | The sample adding device and its loading methods of Full-automatic chemiluminescence analyzer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711491909.1A CN108037304A (en) | 2017-12-30 | 2017-12-30 | The sample adding device and its loading methods of Full-automatic chemiluminescence analyzer |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108037304A true CN108037304A (en) | 2018-05-15 |
Family
ID=62098638
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201711491909.1A Pending CN108037304A (en) | 2017-12-30 | 2017-12-30 | The sample adding device and its loading methods of Full-automatic chemiluminescence analyzer |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108037304A (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108956189A (en) * | 2018-07-23 | 2018-12-07 | 苏州信诺泰克医疗科技有限公司 | Running fix platform, with the reagent needle running fix platform of the running fix platform and its method that walks |
CN109061206A (en) * | 2018-05-31 | 2018-12-21 | 威海威高生物科技有限公司 | Full-automatic illumination analyzer |
CN109324200A (en) * | 2018-12-12 | 2019-02-12 | 深圳普门科技股份有限公司 | Sample analyser |
CN109444450A (en) * | 2018-12-27 | 2019-03-08 | 厦门先明生物技术有限公司 | A kind of whole blood sample automatic sampling apparatus |
CN110208559A (en) * | 2019-06-18 | 2019-09-06 | 广东优尼德生物科技有限公司 | A kind of Biochemical Analyzer |
CN110239946A (en) * | 2019-06-27 | 2019-09-17 | 深圳市爱康生物科技有限公司 | A kind of automatic connection device of refrigeration sample |
CN113574392A (en) * | 2019-01-11 | 2021-10-29 | 迈恩医疗解决方案有限公司 | Pipetting device and method for liquid transfer |
CN114577166A (en) * | 2022-03-08 | 2022-06-03 | 山东华鉴工程检测有限公司 | Bridge cavity crack detector |
CN115407078A (en) * | 2022-11-01 | 2022-11-29 | 丹娜(天津)生物科技股份有限公司 | Analyzer with sample preprocessing function and sample preprocessing method |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001133466A (en) * | 1999-11-05 | 2001-05-18 | Toshiba Corp | Automatic analyzer |
CN104777321A (en) * | 2015-04-16 | 2015-07-15 | 清华大学 | Chemiluminescence immunoassay device |
JP2016183913A (en) * | 2015-03-26 | 2016-10-20 | 株式会社日立ハイテクノロジーズ | Automatic analyzer |
CN106918715A (en) * | 2017-04-27 | 2017-07-04 | 南京诺尔曼生物技术有限公司 | A kind of chemiluminescence diagnostic device and its system |
CN207816998U (en) * | 2017-12-30 | 2018-09-04 | 天津博硕东创科技发展有限公司 | A kind of quick sample-adding reagent adding device of chemiluminescent analyzer |
-
2017
- 2017-12-30 CN CN201711491909.1A patent/CN108037304A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001133466A (en) * | 1999-11-05 | 2001-05-18 | Toshiba Corp | Automatic analyzer |
JP2016183913A (en) * | 2015-03-26 | 2016-10-20 | 株式会社日立ハイテクノロジーズ | Automatic analyzer |
CN104777321A (en) * | 2015-04-16 | 2015-07-15 | 清华大学 | Chemiluminescence immunoassay device |
CN106918715A (en) * | 2017-04-27 | 2017-07-04 | 南京诺尔曼生物技术有限公司 | A kind of chemiluminescence diagnostic device and its system |
CN207816998U (en) * | 2017-12-30 | 2018-09-04 | 天津博硕东创科技发展有限公司 | A kind of quick sample-adding reagent adding device of chemiluminescent analyzer |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109061206A (en) * | 2018-05-31 | 2018-12-21 | 威海威高生物科技有限公司 | Full-automatic illumination analyzer |
CN108956189B (en) * | 2018-07-23 | 2024-03-01 | 苏州信诺泰克医疗科技有限公司 | Movable positioning table, reagent needle movable positioning table with movable positioning table and positioning method thereof |
CN108956189A (en) * | 2018-07-23 | 2018-12-07 | 苏州信诺泰克医疗科技有限公司 | Running fix platform, with the reagent needle running fix platform of the running fix platform and its method that walks |
CN109324200B (en) * | 2018-12-12 | 2022-04-01 | 深圳普门科技股份有限公司 | Sample analyzer |
CN109324200A (en) * | 2018-12-12 | 2019-02-12 | 深圳普门科技股份有限公司 | Sample analyser |
CN109444450A (en) * | 2018-12-27 | 2019-03-08 | 厦门先明生物技术有限公司 | A kind of whole blood sample automatic sampling apparatus |
CN109444450B (en) * | 2018-12-27 | 2022-05-17 | 厦门先明生物技术有限公司 | Whole blood sample autoinjection device |
CN113574392A (en) * | 2019-01-11 | 2021-10-29 | 迈恩医疗解决方案有限公司 | Pipetting device and method for liquid transfer |
CN110208559A (en) * | 2019-06-18 | 2019-09-06 | 广东优尼德生物科技有限公司 | A kind of Biochemical Analyzer |
CN110208559B (en) * | 2019-06-18 | 2024-06-07 | 广东优尼德生物科技有限公司 | Biochemical analyzer |
CN110239946A (en) * | 2019-06-27 | 2019-09-17 | 深圳市爱康生物科技有限公司 | A kind of automatic connection device of refrigeration sample |
CN114577166A (en) * | 2022-03-08 | 2022-06-03 | 山东华鉴工程检测有限公司 | Bridge cavity crack detector |
CN114577166B (en) * | 2022-03-08 | 2023-05-12 | 山东华鉴工程检测有限公司 | Bridge cavity crack detector |
CN115407078A (en) * | 2022-11-01 | 2022-11-29 | 丹娜(天津)生物科技股份有限公司 | Analyzer with sample preprocessing function and sample preprocessing method |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN108037304A (en) | The sample adding device and its loading methods of Full-automatic chemiluminescence analyzer | |
CN108037301A (en) | The reagent tray device and chemiluminescent analyzer of a kind of chemiluminescent analyzer | |
CN103399161B (en) | Portable full-automatic chemiluminescence immune assay system and assay method thereof | |
CN106168626B (en) | Biochip analysis instrument and analysis method | |
JP6843826B2 (en) | Chemiluminescence detector and its detection method | |
WO2018126774A1 (en) | Automatic analysis device and sample analysis method | |
WO2018126773A1 (en) | Automatic analyzer and sample analysis method | |
JP3914837B2 (en) | Automatic analyzer | |
CN110045134B (en) | Full-automatic chemiluminescence immunoassay instrument and use method thereof | |
CN207816998U (en) | A kind of quick sample-adding reagent adding device of chemiluminescent analyzer | |
US20230358647A1 (en) | Integrated constant-temperature fully-automatic cell smear preparation device and method for automatic cytology slide preparation | |
CN108761112A (en) | Analytical equipment for being diagnosed in test tube | |
CN208833787U (en) | Chemiluminescence detector | |
CN212646715U (en) | Full-automatic analyzer | |
CN113267639A (en) | Automatic immunity analyzer | |
CN116148027B (en) | Sample preparation instrument | |
CN108663502A (en) | Full-automatic thrombelastogram instrument | |
CN114280316A (en) | Full-automatic COD analytical equipment | |
CN205384283U (en) | Immunofluorescence analyzer | |
CN108414780B (en) | Automatic sample loading device for test tube | |
CN211043051U (en) | Tray assembly and specific surface area tester | |
CN207816997U (en) | The reagent disc and chemiluminescent analyzer of Full-automatic chemiluminescence analyzer | |
CN109324200A (en) | Sample analyser | |
CN205809087U (en) | Full-automatic detection apparatus and there is the genital discharge analyte detection equipment of this device | |
CN212483498U (en) | Automatic rapid titration detection device for COD (chemical oxygen demand) with cleaning function |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |