CN108024955A - 用于rsv和诺如病毒抗原的小肠递送的制剂 - Google Patents

用于rsv和诺如病毒抗原的小肠递送的制剂 Download PDF

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Publication number
CN108024955A
CN108024955A CN201680046440.8A CN201680046440A CN108024955A CN 108024955 A CN108024955 A CN 108024955A CN 201680046440 A CN201680046440 A CN 201680046440A CN 108024955 A CN108024955 A CN 108024955A
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Prior art keywords
vaccine
rsv
group
immunogenic composition
subjects
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Pending
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CN201680046440.8A
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Chinese (zh)
Inventor
乔治·特拉格
肖恩·塔克
金利宣
夏兰·斯卡伦
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Vaxart Inc
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Vaxart Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57503876&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN108024955(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vaxart Inc filed Critical Vaxart Inc
Priority to CN202311287963.XA priority Critical patent/CN118045170A/zh
Publication of CN108024955A publication Critical patent/CN108024955A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0058Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00Medicinal preparations characterised by special physical form
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    • A61K9/2004Excipients; Inactive ingredients
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    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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    • AHUMAN NECESSITIES
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    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
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    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10041Use of virus, viral particle or viral elements as a vector
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    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
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    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
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    • C12N2770/16011Caliciviridae
    • C12N2770/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201680046440.8A 2015-06-12 2016-06-08 用于rsv和诺如病毒抗原的小肠递送的制剂 Pending CN108024955A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311287963.XA CN118045170A (zh) 2015-06-12 2016-06-08 用于rsv和诺如病毒抗原的小肠递送的制剂

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US201562175081P 2015-06-12 2015-06-12
US62/175,081 2015-06-12
PCT/US2016/036461 WO2016200951A1 (en) 2015-06-12 2016-06-08 Formulations for small intestinal delivery of rsv and norovirus antigens

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CN202311287963.XA Division CN118045170A (zh) 2015-06-12 2016-06-08 用于rsv和诺如病毒抗原的小肠递送的制剂

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CN201680046440.8A Pending CN108024955A (zh) 2015-06-12 2016-06-08 用于rsv和诺如病毒抗原的小肠递送的制剂

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US (3) US11433146B2 (enExample)
EP (2) EP3791859A1 (enExample)
JP (2) JP6912394B2 (enExample)
KR (2) KR102678401B1 (enExample)
CN (2) CN118045170A (enExample)
AU (1) AU2016274599B2 (enExample)
CA (1) CA2988761A1 (enExample)
DK (1) DK3307239T3 (enExample)
EA (1) EA201792512A1 (enExample)
ES (1) ES2832504T3 (enExample)
WO (1) WO2016200951A1 (enExample)
ZA (1) ZA201708434B (enExample)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN108904795A (zh) * 2018-08-29 2018-11-30 温氏食品集团股份有限公司 一种猪流行性腹泻病毒的口服疫苗的制备方法

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CA2988761A1 (en) 2015-06-12 2016-12-15 Vaxart, Inc. Formulations for small intestinal delivery of rsv and norovirus antigens
EP3565591A1 (en) * 2017-01-06 2019-11-13 Stabilitech Biopharma Ltd Virus
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US20210311600A1 (en) * 2020-04-06 2021-10-07 Kirk David Bacon Seat Selection Application For Social Distancing Compliance
WO2024193965A1 (en) * 2023-03-17 2024-09-26 Glaxosmithkline Biologicals Sa Rsv-f-encoding nucleic acids

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