CN108020545B - Urine iodine analyzer - Google Patents
Urine iodine analyzer Download PDFInfo
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- CN108020545B CN108020545B CN201711430870.2A CN201711430870A CN108020545B CN 108020545 B CN108020545 B CN 108020545B CN 201711430870 A CN201711430870 A CN 201711430870A CN 108020545 B CN108020545 B CN 108020545B
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- 210000002700 urine Anatomy 0.000 title claims abstract description 64
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 title claims abstract description 36
- 239000011630 iodine Substances 0.000 title claims abstract description 36
- 229910052740 iodine Inorganic materials 0.000 title claims abstract description 36
- 238000001514 detection method Methods 0.000 claims abstract description 64
- 230000007246 mechanism Effects 0.000 claims abstract description 31
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 19
- 238000002156 mixing Methods 0.000 claims abstract description 17
- 239000011324 bead Substances 0.000 claims description 17
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 16
- 238000002347 injection Methods 0.000 claims description 16
- 239000007924 injection Substances 0.000 claims description 16
- 239000013307 optical fiber Substances 0.000 claims description 12
- 238000004458 analytical method Methods 0.000 claims description 9
- 238000010438 heat treatment Methods 0.000 claims description 9
- 230000003287 optical effect Effects 0.000 claims description 8
- 238000004321 preservation Methods 0.000 claims description 8
- 230000002485 urinary effect Effects 0.000 claims description 5
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 3
- 229910052736 halogen Inorganic materials 0.000 claims description 3
- 150000002367 halogens Chemical class 0.000 claims description 3
- 229910052710 silicon Inorganic materials 0.000 claims description 3
- 239000010703 silicon Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 abstract description 8
- 238000010907 mechanical stirring Methods 0.000 abstract description 4
- 230000035764 nutrition Effects 0.000 abstract description 4
- 235000016709 nutrition Nutrition 0.000 abstract description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 12
- 238000003825 pressing Methods 0.000 description 8
- 238000009413 insulation Methods 0.000 description 6
- 229910052742 iron Inorganic materials 0.000 description 6
- 238000010586 diagram Methods 0.000 description 3
- 206010067997 Iodine deficiency Diseases 0.000 description 2
- 208000036626 Mental retardation Diseases 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 235000006479 iodine deficiency Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000005353 urine analysis Methods 0.000 description 2
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 208000003532 hypothyroidism Diseases 0.000 description 1
- 230000002989 hypothyroidism Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000036244 malformation Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000011895 specific detection Methods 0.000 description 1
- 208000002254 stillbirth Diseases 0.000 description 1
- 231100000537 stillbirth Toxicity 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 208000014001 urinary system disease Diseases 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Engineering & Computer Science (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a urine iodine analyzer, which comprises a shell, a mixing mechanism, a detection mechanism and a control unit, wherein a first clamping groove is formed in one side wall of the shell, a cuvette is detachably clamped in the first clamping groove, and coaxial detection holes are respectively formed in two opposite side walls in the first clamping groove; the mixing mechanism is used for driving urine to be detected and chemical reagents in the cuvette to be uniformly mixed; the detection mechanism is arranged in the shell and used for detecting and analyzing urine to be detected in the cuvette. The urine iodine analyzer provided by the technical scheme of the invention has the advantages of simple structure, convenience in use and low cost, is particularly used in places such as families or community centers, can be used for evaluating the iodine nutrition status of detected people by detecting and analyzing the iodine content in urine, can be used for rapidly and fully mixing and reacting the urine in the cuvette with chemical reagents through the mixing mechanism, and avoids the problem that the detection precision is affected due to liquid splashing out of the cuvette caused by mechanical stirring or hand-operated mode.
Description
Technical Field
The invention relates to the technical field of medical detection instruments, in particular to a urine iodine analyzer.
Background
Urine analysis is one of the most commonly used clinical test indexes, and is helpful for diagnosing urinary system diseases and treating diseases, and also for diagnosing other system diseases which can cause the change of biochemical components of blood. In addition, urine analysis can also be used for safety medication detection and health status initial assessment.
The iodine content in urine is the focus of routine detection, and is an index for judging the iodine nutrition status of individuals or groups, and is also an epidemiological index for evaluating the iodine deficiency degree. Iodine is an essential trace element of human body, and iodine deficiency can lead to abortion, stillbirth, congenital malformation, hypothyroidism, mental retardation, physical retardation, simple deaf-mutes and other defects, while excessive iodine can lead to mental retardation.
The existing urine iodine detection equipment is generally complex in structure and high in cost, and a common family, a social health center or a small-sized clinic cannot be equipped with the equipment, and due to the complex operation steps, detection can be accurately performed by specially trained personnel.
Disclosure of Invention
The invention aims to at least solve the defects in the prior art to a certain extent and provides a urine iodine analyzer.
In order to achieve the above object, the present invention provides a urine iodine analyzer comprising:
the device comprises a shell, wherein a first clamping groove is formed in one side wall of the shell, a cuvette is detachably clamped in the first clamping groove, coaxial detection holes are respectively formed in two opposite side walls in the first clamping groove, and the cuvette is used for accommodating urine to be detected and chemical reagents;
the mixing mechanism comprises magnetic beads accommodated in the cuvette and a driving motor arranged in the shell, wherein an output shaft of the driving motor extends to the tail end close to the first clamping groove and is fixedly provided with a magnet, and the driving motor is used for driving the magnet to rotate so as to drive the magnetic beads in the cuvette to move by utilizing magnetic force, so that urine to be detected and chemical reagents in the cuvette are uniformly mixed;
the detection mechanism is arranged in the shell and used for detecting and analyzing urine to be detected in the cuvette, the detection mechanism comprises a light source assembly and a data acquisition device which are oppositely arranged, the light source assembly is opposite to a detection hole on one side wall of the first clamping groove, and the data acquisition device is opposite to a detection hole on the other side wall of the first clamping groove;
the control unit is arranged in the shell and is respectively connected with the driving motor, the light source assembly and the data acquisition device in a signal mode.
Preferably, a second clamping groove is further formed in the side wall of the shell along the vertical direction, the lower end of the second clamping groove is communicated with the first clamping groove, the upper end of the second clamping groove extends to penetrate through the top wall of the shell, and a sample injector for injecting urine to be detected into the cuvette is detachably clamped in the second clamping groove.
Preferably, the sample injector comprises a syringe and a plunger rod which is matched with the syringe and can be pulled out from the syringe, an activated carbon layer is arranged at the bottom end in the syringe, and filter papers are respectively arranged on the upper surface and the lower surface of the activated carbon layer.
Preferably, an annular protrusion is formed on the periphery of the upper end of the injection tube in a radial extending manner, a stop step matched with the annular protrusion is arranged on the upper end of the second clamping groove, and when the injection tube is clamped into the second clamping groove, the injection tube is limited to move downwards through the cooperation of the annular protrusion and the stop step.
Preferably, the light source assembly comprises a mounting frame fixed with the housing, a light source, a lens and an optical filter are sequentially arranged on the mounting frame along the axis direction of the detection hole, the light source is connected with the lens through an optical fiber, and light rays emitted by the light source sequentially pass through the optical fiber, the lens and the optical filter and then pass through the cuvette to be received by the data collector.
Preferably, the light source assembly further comprises a mounting seat, the mounting seat is slidably arranged on the mounting frame along the axis direction of the detection hole, the light source is mounted in the mounting seat, one end of the optical fiber penetrates into the mounting seat to be opposite to the light source, and the other end penetrates into the mounting frame to be opposite to the lens.
Preferably, the light source is an LED light source, a laser diode or a halogen lamp, and the data collector is a spectrometer or a silicon photocell.
Preferably, the device further comprises a touch display screen and a printer, wherein the touch display screen is connected with the control unit and used for displaying and controlling the detection result, and the printer is used for printing the detection analysis result of the detection mechanism.
Preferably, the incubator further comprises an incubator arranged in the first clamping groove, the incubator comprises a heat preservation sleeve and a heating plate wrapping the heat preservation sleeve, light holes are formed in positions, corresponding to the detection holes, on two opposite side walls of the heating plate and the heat preservation sleeve, and the cuvette is detachably clamped in the heat preservation sleeve.
Preferably, the output shaft of the driving motor is horizontally arranged, a mounting plate perpendicular to the output shaft is fixedly sleeved on the tail end of the output shaft, and two magnets are symmetrically fixed on the side wall of the mounting plate facing the first clamping groove and opposite to the output shaft.
The urine iodine analyzer provided by the technical scheme of the invention has the advantages of simple structure, convenience in use and low cost, is particularly used in places such as families or community centers, can be used for evaluating the iodine nutrition status of detected people by detecting and analyzing the iodine content in urine, can be used for rapidly and fully mixing and reacting the urine in the cuvette with chemical reagents through the mixing mechanism, and avoids the problem that the detection precision is affected due to liquid splashing out of the cuvette caused by mechanical stirring or hand-operated mode.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of the structure of a urine iodine analyzer of the present invention;
FIG. 2 is a schematic diagram showing an exploded structure of the urine iodine analyzer of the present invention;
FIG. 3 is a schematic view showing a partial sectional structure of the urine iodine analyzer of the present invention;
FIG. 4 is a schematic diagram of the position structure of the cuvette and mixing mechanism and detection mechanism of the present invention;
FIG. 5 is an exploded view of the light source module of the present invention;
fig. 6 is a schematic structural view of the mixing mechanism of the present invention.
The achievement of the objects, functional features and advantages of the present invention will be further described with reference to the accompanying drawings, in conjunction with the embodiments.
Detailed Description
Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below are exemplary and intended to illustrate the present invention and should not be construed as limiting the invention, and all other embodiments, based on the embodiments of the present invention, which may be obtained by persons of ordinary skill in the art without inventive effort, are within the scope of the present invention.
In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "circumferential", "radial", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present invention and simplify the description, and do not indicate or imply that the device or element being referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present invention.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present invention, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
In the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances.
In the present invention, unless expressly stated or limited otherwise, a first feature "above" or "below" a second feature may include both the first and second features being in direct contact, as well as the first and second features not being in direct contact but being in contact with each other through additional features therebetween. Moreover, a first feature being "above," "over" and "on" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly under and obliquely below the second feature, or simply means that the first feature is less level than the second feature.
An urine iodine analyzer according to an embodiment of the present invention will be described in detail with reference to the accompanying drawings.
As shown in fig. 1 to 6, the urinary iodine analyzer according to the embodiment of the present invention includes a housing 10, a cuvette 20, a mixing mechanism 30, a detecting mechanism 40, and a control unit 50.
Specifically, a first clamping groove 111 is provided on a side wall of the housing 10, a cuvette 20 is detachably clamped in the first clamping groove 111, coaxial detection holes 112 are respectively provided on two opposite side walls in the first clamping groove 111, and the cuvette 20 is used for accommodating urine and chemical reagents to be detected. In the detection process, a proper amount of urine to be detected and a chemical reagent are added into the cuvette 20 for reaction, and then the cuvette 20 is clamped into the first clamping groove 111; the chemical reagent in this embodiment is generally a mixed liquid with a color developing agent and an oxidizing agent or other similar reagents with the same function, and is a known reagent, and will not be described herein. Of course, the pre-treated urine may be directly added to the cuvette 20 for detection.
The mixing mechanism 30 comprises a magnetic bead or an iron bead accommodated in the cuvette 20 and a driving motor 31 arranged in the housing 10, an output shaft 32 of the driving motor 31 extends to be close to the tail end of the first clamping groove 111, a magnet 34 is fixedly arranged on the tail end of the driving motor 31, the driving motor 31 is used for driving the magnet 34 to rotate, and magnetic beads in the cuvette 20 are driven to move by magnetic force, so that urine to be detected and chemical reagents in the cuvette 20 are uniformly mixed and fully reacted, the purpose of mixing reaction can be achieved without a mechanical stirring mechanism, and meanwhile, the problem that liquid splashes out of the cuvette 20 to influence the detection precision is avoided.
The detection mechanism 40 is disposed in the housing 10 and is used for detecting and analyzing urine to be detected in the cuvette 20, the detection mechanism 40 includes a light source assembly 41 and a data collector 42 that are disposed opposite to each other, the light source assembly 41 is opposite to a detection hole 112 on one side wall of the first clamping groove 111, and the data collector 42 is opposite to the detection hole 112 on the other side wall of the first clamping groove 111; thus, the light emitted by the light source assembly 41 passes through the detection hole 112 to irradiate the urine in the cuvette 20 to generate reflected light, and the data collector 42 analyzes the content of iodine in the urine by receiving the reflected light, which can also analyze the content of other substances in the urine.
The control unit 50 is disposed in the housing 10 and is respectively connected to the driving motor 31, the light source assembly 41 and the data collector 42 in a signal manner, so as to control the above modules to cooperatively operate. Preferably, the urine iodine analyzer of the present embodiment further includes a touch display screen 13 and a printer 14 connected to the control unit 50, where the touch display screen 13 is configured to display and control the detection result, so that a user can more intuitively learn the detection result and perform control on the touch display screen 13; the printer 14 is used for printing the detection analysis result of the detection mechanism 40.
In one embodiment of the present invention, as shown in fig. 2, the housing 10 of the urine iodine analyzer has a generally rectangular structure, and includes a housing 11 and a back cover plate 12, wherein a rear side wall of the housing 11 is open, the back cover plate 12 covers the opening and forms a containing cavity with the housing 11, the mixing mechanism 30, the detecting mechanism 40, the control unit 50 and the printer 14 are all installed in the containing cavity, the first clamping groove 111 and the touch display 13 are all disposed on a front side wall of the housing 11, the first clamping groove 111, the mixing mechanism 30 and the detecting mechanism 40 are disposed at a bottom of the housing 11, and the printer 14 is disposed at a top of the housing 11; further, the storage battery 15 is fixed on the inner side of the back cover plate 12, the USB interface 51, the switching power supply 16 and the speaker hole 114 are further provided on the housing 11, a speaker 17 for broadcasting a detection analysis result or a prompt tone is provided at a position corresponding to the speaker hole 114 in the accommodating cavity, and data of the detection analysis result can be exported through the USB interface 51, and the storage battery 15 can also be charged.
In one embodiment of the present invention, as shown in fig. 2 and 3, a second clamping groove 113 is further provided on the one side wall of the housing 10 along the vertical direction, the lower end of the second clamping groove is communicated with the first clamping groove 111, the upper end of the second clamping groove extends out of the top wall of the housing 11, and a sample injector 60 for injecting urine to be detected into the cuvette 20 is detachably engaged in the second clamping groove 113. That is, in the specific detection, an appropriate amount of chemical reagent and magnetic beads or iron beads are added to the cuvette 20 and clamped into the first clamping groove 111; the sample injector 60 is used for storing urine to be detected and is clamped into the second clamping groove 113, the sample injector 60 is operated to inject a proper amount of urine into the cuvette 20, and then the magnet 34 on the output shaft 32 of the sample injector 31 is started to rotate so as to drive the magnetic beads or the iron beads in the cuvette 20 to move, so that the urine and the chemical reagent in the cuvette 20 are uniformly mixed, and the detection mechanism 40 is used for detecting the mixed liquid in the cuvette 20; in actual use, urine of different human bodies can be stored in different sample applicators 60 in advance, and the urine is directly arranged in the first clamping groove 111 when detection is needed, so that the operation is simple, and the detection effect is high.
Further, the sample injector 60 in this embodiment is a disposable product, and includes a syringe 61 and a plunger rod 62 that is matched with the syringe 61 and can be pulled out from the syringe 61, an activated carbon layer 63 is disposed on the bottom end in the syringe 61, and filter papers 64 are disposed on the upper and lower surfaces of the activated carbon layer 63 respectively. When the urine to be detected is required to be detected, the plunger rod 62 can be extracted from the upper end of the injection tube 61, the urine to be detected is poured into the injection tube 61, the injection tube 61 is clamped into the second clamping groove 113, then the plunger rod 62 is plugged into the injection tube 61 and is pressed downwards, the urine to be detected poured into the injection tube 61 is filtered and purified under the action of the filter paper 64 and the activated carbon layer 63 under pressure, and then falls into the cuvette 20, so that impurities in the urine to be detected are filtered, and higher detection precision can be obtained when the detection mechanism 40 detects the urine after filtration and purification.
Further, an annular protrusion 611 is formed on the upper end periphery of the syringe 61 along the radial direction, a stop step 1131 matching with the annular protrusion 611 is provided on the upper end of the second clamping groove 113, when the syringe 61 is clamped into the second clamping groove 113, the downward movement of the syringe 61 is limited by the matching of the annular protrusion 611 and the stop step 1131, so that an operator can directly press the top end of the plunger rod 62 to press the urine in the syringe 61 by the downward movement, and the purpose of filtering and purifying the urine to be detected is achieved.
In one embodiment of the present invention, as shown in fig. 4 and 5, the light source assembly 41 includes a mounting frame 411 fixed to the housing 10, a light source 412, a lens 413 and a light filter 414 are sequentially disposed on the mounting frame 411 along the axial direction of the detection hole 112, the light source 412 is connected to the lens 413 through an optical fiber 415, and the light emitted by the light source 412 passes through the optical fiber 415, the lens 413 and the light filter 414 in sequence and then passes through the cuvette 20 to be received by the data collector 42. Therefore, the light emitted by the light source 412 can be calibrated through the optical fiber 415 and the lens 413, so that the light loss is avoided, and meanwhile, the light with the color of the unnecessary wave band can be filtered through the optical filter 414, so that the detection precision is improved.
The light source 412 assembly 41 further includes a mounting seat 416, the mounting seat 416 is slidably disposed on the mounting frame 411 along the axial direction of the detection hole 112, the light source 412 is mounted in the mounting seat 416, one end of the optical fiber 415 penetrates into the mounting seat 416 to be opposite to the light source 412, and the other end penetrates into the mounting frame 411 to be opposite to the lens 413. Specifically, an end wall of the mounting seat 416, which is far away from the lens 413, is provided with a first accommodating groove for accommodating the light source 412, and is fixed on the end wall of the mounting seat 416 through a first pressing plate 417 so as to limit and fix the light source 412 in the first accommodating groove; the end wall of the mounting frame 411 far away from the mounting seat 416 is provided with a second accommodating groove 4111 which is communicated with the optical fiber 415 and used for accommodating the lens 413, and the second accommodating groove 4111 is fixed on the end wall of the mounting frame 411 through a second pressing plate 418 so as to limit and fix the lens 413 in the second accommodating groove 4111; a third accommodating groove 4181 communicated with the lens 413 and used for accommodating the optical filter 414 is formed in the outer side wall of the second pressing plate 418, the optical filter 414 is limited and fixed in the third accommodating groove 4181 by the third pressing plate 419, and a through hole 4191 is formed in the position, corresponding to the optical filter 414, of the third pressing plate 419; the mounting frame 411 is fastened to the second pressing plate 418 and the third pressing plate 419 by fastening means, and at this time, the centers of the first receiving groove, the second receiving groove 4111, the third receiving groove 4181, and the optical fiber 415 are all on the same line, and the light emitted from the light source 412 is emitted from the through hole 4191 along the line, and the emitted light passes through the detection hole 112 to be irradiated on the cuvette 20.
It will be appreciated that the light source 412 is an LED light source 412, a laser diode or a halogen lamp, and the data collector 42 is a spectrometer or a silicon photocell.
In some embodiments of the present invention, as shown in fig. 2, the urine iodine analyzer of the present invention further includes an incubator 70 disposed in the first clamping groove 111, the incubator 70 includes a heat insulation sleeve 72 and a heating sheet 71 wrapping the heat insulation sleeve 72, light holes 73 are formed on opposite side walls of the heating sheet 71 and the heat insulation sleeve 72 corresponding to the positions of the detection holes 112, and the cuvette 20 is detachably clamped in the heat insulation sleeve 72. That is, the heating plate 71 and the heat insulation sleeve 72 are fixed in the first clamping groove 111, and during detection and analysis, the cuvette 20 can be clamped into the heat insulation sleeve 72, and the heating plate 71 is used for heating, so that the liquid to be detected in the cuvette 20 is heated and kept at a set temperature, the detection and analysis of the liquid to be detected in a proper temperature range are ensured, and the detection accuracy is ensured.
In some embodiments of the present invention, the output shaft 32 of the driving motor 31 is disposed horizontally and perpendicular to the axis of the detection hole 112, a mounting plate 33 perpendicular to the output shaft 32 is fixedly sleeved on the end of the output shaft, and two magnets 34 are symmetrically fixed on the side wall of the mounting plate 33 facing the first clamping groove 111, opposite to the output shaft 32. Thus, when the driving motor 31 drives the mounting plate 33 to rotate, the two magnets 34 rotate around the axis of the output shaft 32, so as to generate a continuously changing magnetic field to drive the magnetic beads or the iron beads in the cuvette 20 to roll, thereby achieving the purpose of fully mixing and reacting the urine and the chemical reagent added in the cuvette 20.
The application process of the invention is as follows:
s1, adding a proper amount of chemical reagent and a plurality of magnetic beads or iron beads into the cuvette 20, and then clamping the cuvette 20 into a first clamping groove 111 for fixation;
s2, after the plunger rod 62 of the sample injector 60 is extracted from the injection cylinder 61, pouring urine to be detected into the injection cylinder 61, after the injection cylinder 61 is clamped into the second clamping groove 113, plugging the plunger rod 62 into the injection cylinder 61, and applying pressure to enable the plunger rod 62 to move downwards so as to filter and purify the urine to be detected in the injection cylinder 61 through the filter paper 64 and the activated carbon layer 63, and then pouring the urine into the cuvette 20 in the second clamping groove 113;
s3, starting a driving motor 31 in the urine iodine analyzer to control magnetic beads or iron beads in the cuvette 20 to roll so as to uniformly mix chemical reagents with urine for reaction;
and S4, detecting and analyzing the urine in the cuvette 20 by utilizing the light source 412 assemblies 41 and the data collector 42 at the two sides of the cuvette 20, so as to obtain the iodine content in the urine.
In summary, the urine iodine analyzer of the present invention has simple structure, convenient use and low cost, and is particularly used in places such as home or community center, and the detection and analysis result can be used for evaluating the iodine nutrition status of the detected crowd through the detection and analysis of the iodine content in urine, and the urine in the cuvette 20 and the chemical reagent can be rapidly and fully mixed and reacted through the mixing mechanism 30, so that the problem that the inspection accuracy is affected due to the liquid splashing out of the cuvette 20 caused by mechanical stirring or hand-shaking is avoided.
The foregoing description is only of the preferred embodiments of the present invention and is not intended to limit the scope of the invention, and all equivalent structural changes made by the description of the present invention and the accompanying drawings or direct/indirect application in other related technical fields are included in the scope of the invention.
Claims (5)
1. A urinary iodine analyzer, comprising:
the device comprises a shell, wherein a first clamping groove is formed in one side wall of the shell, a cuvette is detachably clamped in the first clamping groove, coaxial detection holes are respectively formed in two opposite side walls in the first clamping groove, and the cuvette is used for accommodating urine to be detected and chemical reagents;
the mixing mechanism comprises magnetic beads accommodated in the cuvette and a driving motor arranged in the shell, wherein an output shaft of the driving motor extends to the tail end close to the first clamping groove and is fixedly provided with a magnet, and the driving motor is used for driving the magnet to rotate so as to drive the magnetic beads in the cuvette to move by utilizing magnetic force, so that urine to be detected and chemical reagents in the cuvette are uniformly mixed;
the detection mechanism is arranged in the shell and used for detecting and analyzing urine to be detected in the cuvette, the detection mechanism comprises a light source assembly and a data acquisition device which are oppositely arranged, the light source assembly is opposite to a detection hole on one side wall of the first clamping groove, and the data acquisition device is opposite to a detection hole on the other side wall of the first clamping groove;
the control unit is arranged in the shell and is respectively connected with the driving motor, the light source assembly and the data acquisition device in a signal manner;
a second clamping groove is further formed in the side wall of the shell along the vertical direction, the lower end of the second clamping groove is communicated with the first clamping groove, the upper end of the second clamping groove extends to penetrate through the top wall of the shell, and a sample injector for injecting urine to be detected into the cuvette is detachably clamped in the second clamping groove;
the sample injector comprises a syringe and a plunger rod which is matched with the syringe and can be pulled out from the syringe, an activated carbon layer is arranged at the bottom end in the syringe, and filter papers are respectively arranged on the upper surface and the lower surface of the activated carbon layer;
the upper end periphery of the injection tube extends along the radial direction to form an annular bulge, the upper end of the second clamping groove is provided with a stop step matched with the annular bulge, and when the injection tube is clamped into the second clamping groove, the downward movement of the injection tube is limited by the cooperation of the annular bulge and the stop step;
the light source assembly comprises a mounting frame fixed with the shell, a light source, a lens and an optical filter are sequentially arranged on the mounting frame along the axis direction of the detection hole, the light source is connected with the lens through an optical fiber, and light rays emitted by the light source sequentially pass through the optical fiber, the lens and the optical filter and then pass through the cuvette to be received by the data collector;
the incubator comprises a heat preservation sleeve and a heating plate wrapping the heat preservation sleeve, light holes are formed in positions, corresponding to the detection holes, on two opposite side walls of the heating plate and the heat preservation sleeve, and the cuvette is detachably clamped in the heat preservation sleeve.
2. The urinary iodine analyzer of claim 1 wherein the light source assembly further comprises a mounting base slidably disposed on the mounting frame along an axial direction of the detection aperture, the light source is mounted in the mounting base, one end of the optical fiber penetrates the mounting base opposite the light source, and the other end penetrates the mounting frame opposite the lens.
3. The urinary iodine analyzer of claim 2 wherein the light source is an LED light source, a laser diode or a halogen lamp and the data collector is a spectrometer or a silicon photocell.
4. The urinary iodine analyzer of claim 1, further comprising a touch display screen and a printer connected to the control unit, wherein the touch display screen is configured to display and control the detection result, and the printer is configured to print the detection analysis result of the detection mechanism.
5. The urine iodine analyzer of claim 1 wherein the output shaft of the drive motor is disposed horizontally, a mounting plate perpendicular to the output shaft is fixedly sleeved on the end of the output shaft, and two magnets are symmetrically fixed on the side wall of the mounting plate facing the first clamping groove relative to the output shaft.
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| CN201711430870.2A CN108020545B (en) | 2017-12-26 | 2017-12-26 | Urine iodine analyzer |
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| CN201711430870.2A CN108020545B (en) | 2017-12-26 | 2017-12-26 | Urine iodine analyzer |
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| CN108020545B true CN108020545B (en) | 2024-02-09 |
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| CN112697783A (en) * | 2020-12-23 | 2021-04-23 | 太原理工大学 | Quantitative detection device and method for urine iodine |
| CN115248318B (en) * | 2022-09-21 | 2022-12-13 | 南京颐兰贝生物科技有限责任公司 | Detection method of blood coagulation analyzer |
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