CN220626216U

CN220626216U - Carboxyhemoglobin detection device

Info

Publication number: CN220626216U
Application number: CN202322256750.2U
Authority: CN
Inventors: 杨聪; 刘东升
Original assignee: Meizhou Cornley Hi Tech Co ltd
Current assignee: Meizhou Cornley Hi Tech Co ltd
Priority date: 2023-08-21
Filing date: 2023-08-21
Publication date: 2024-03-19
Anticipated expiration: 2033-08-21

Abstract

The utility model discloses a carboxyhemoglobin detection device which comprises an optical system module, a detection container and a mixing module which are connected with each other, wherein the optical system module comprises a light source and a detection part, the light source is arranged opposite to the detection container and can irradiate the detection container, the mixing module is connected with the detection container and can mix samples to be detected in the detection container uniformly, and the detection part is used for detecting optical signals before and after the mixed samples to be detected are added into the detection container. The detection device provided by the utility model can be used for detecting and processing the optical signals of the detection container irradiated by the light source after the sample to be detected is uniformly mixed and the optical signals before the sample to be detected is not added into the detection container, so that the concentration of carbon monoxide in blood can be rapidly and accurately measured based on a dual-wavelength detection method, and the device has the characteristics of simple structure, convenience in operation, convenience in use, low cost, high accuracy, wide application range and easiness in microminiaturization and portability.

Description

Carboxyhemoglobin detection device

Technical Field

The utility model relates to the technical field of carboxyhemoglobin detection, in particular to a carboxyhemoglobin detection device.

Background

At present, along with the development of science, the requirement of each application field on the real-time performance of analysis and test results is continuously improved, and on-site rapid analysis has become one of the development trends of analysis science. In-situ analysis has been a major aspect of the development of analytical instruments, which has been increasingly demanded by miniaturization and portability of analytical instruments. The blood is the only material for detecting carbon monoxide poisoning, and the determination of the carbon monoxide concentration in the blood is required to be made to determine whether the patient is poisoned or not, so that the carbon monoxide concentration in the blood needs to be rapidly and accurately determined under the condition that the illness state of the poisoned patient is unknown, and the follow-up doctor is facilitated.

However, the current detection device has a large general volume, is only suitable for measuring carbon monoxide in blood in a laboratory, requires preheating of a light source before measurement, also requires periodic maintenance, has high maintenance cost, is inconvenient to operate, has a complex structure, and cannot quickly and accurately obtain a test result.

In view of this, there is a need for further improvements in the current structure of carbon-oxygen protein detection.

Disclosure of Invention

The object of the present utility model is to solve at least some of the disadvantages of the prior art and to provide a carboxyhemoglobin detection apparatus.

In order to achieve the above purpose, the utility model adopts a technical scheme that:

the utility model provides a carboxyhemoglobin detection device which comprises an optical system module, a detection container and a mixing module which are connected with each other, wherein the optical system module comprises a light source and a detection piece, the light source is arranged opposite to the detection container and can irradiate the detection container, the mixing module is connected with the detection container and can mix samples to be detected in the detection container, and the detection piece is used for detecting optical signals before and after the mixed samples to be detected are added into the detection container.

Further, the mixing module comprises a driving piece, a magnetic piece and a stirring piece, wherein the driving piece is connected with the magnetic piece, the stirring piece is arranged in the detection container, and the driving piece can drive the magnetic piece to drive the stirring piece to mix the sample to be detected in the detection container.

Further, the optical system module further comprises an elastic piece, and the elastic piece is fixedly connected with the detection container.

Further, the optical system module further comprises a connecting seat, a limiting groove is formed in the connecting seat, one end of the detection container is inserted into the limiting groove, one end of the elastic piece is connected with the detection container, and the other end of the elastic piece is connected with the limiting groove.

Further, the connecting seat is further provided with a first through hole and a second through hole, the first through hole is communicated with the light source and the limiting groove so that the light source irradiates the detection container, and the second through hole is communicated with the limiting groove and the detection piece so that the detection piece receives the irradiated light signals of the detection container.

Further, the optical system comprises a touch screen and a control main board, wherein the touch screen is electrically connected with the control main board, and the control main board is electrically connected with the optical system module and the mixing module.

Further, the printing device further comprises a printing module and a power supply module, wherein the printing module and the power supply module are electrically connected with the control main board.

Further, the device also comprises a shell, wherein the optical system module, the detection container, the mixing module, the control main board, the printing module and the power supply module are all arranged in the shell.

Further, the optical system module comprises a cover plate, wherein the cover plate is arranged on the shell and is positioned close to the optical system module; the touch screen is also arranged on the shell.

Further, the detection piece is a spectrophotometer; the detection container is a disposable cuvette.

The utility model provides a carboxyhemoglobin detection device which comprises an optical system module, a detection container and a mixing module which are connected with each other, wherein the optical system module comprises a light source and a detection piece, the light source is arranged opposite to the detection container and can irradiate the detection container, the mixing module is connected with the detection container and can mix samples to be detected in the detection container, and the detection piece is used for detecting optical signals before and after the mixed samples to be detected are added into the detection container. The detection device provided by the utility model can be used for detecting and processing the optical signals of the detection container irradiated by the light source after the sample to be detected is uniformly mixed and the optical signals before the sample to be detected is not added into the detection container, so that the concentration of carbon monoxide in blood can be rapidly and accurately measured based on a dual-wavelength detection method, and the device has the characteristics of simple structure, convenience in operation, convenience in use, low cost, high accuracy, wide application range and easiness in microminiaturization and portability.

Drawings

In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present utility model, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic diagram of an exploded structure of a carboxyhemoglobin detection apparatus of the present utility model;

FIG. 2 is a sectional view showing an exploded structure of the carboxyhemoglobin measurement apparatus of the present utility model.

The reference numerals in the drawings are as follows: 1-an optical system module; 11-a light source; 12-detecting piece; 13-an elastic member; 14-connecting seats; 2-a detection container; 3-uniformly mixing the components; 31-a driving member; 32-magnetic member; 33-stirring piece; 4-a touch screen; 5-a control main board; a 6-print module; 7-a power supply module; 8-a housing; 9-cover plate.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

It should be noted that the description of "first," "second," etc. in this disclosure is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions of the embodiments may be combined with each other, but it is necessary to base that the technical solutions can be realized by those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should be considered to be absent and not within the scope of protection claimed in the present utility model.

Referring to fig. 1 to 2, the utility model provides a carboxyhemoglobin detection apparatus, which comprises an optical system module 1, a detection container 2 and a mixing module 3 that are connected with each other, wherein the optical system module 1 comprises a light source 11 and a detection member 12, the light source 11 is arranged opposite to the detection container 2 and can irradiate the detection container 2, the mixing module 3 is connected with the detection container 2 and can mix samples to be detected in the detection container 2, and the detection member 12 is used for detecting optical signals before and after the detection container 2 is added into the mixed samples to be detected.

In this embodiment, the carboxyhemoglobin detection apparatus includes an optical system module 1, a detection container 2, and a mixing module 3, where the optical system module 1 is a module for measuring carboxyhemoglobin in blood by using a dual wavelength detection method, the detection container 2 is used for containing blood to be detected, i.e. a sample to be detected, and the mixing module 3 is used for mixing the sample to be detected in the detection container 2.

Specifically, the optical system module 1 includes a light source 11 for irradiating the inspection container 2 and a detecting member 12 for collecting an off signal when the light source 11 irradiates the inspection container 2. The principle of the dual wavelength detection method is based on a colorimetric method, i.e. determining the concentration of a sample by comparing the difference in absorbance of the sample and a standard solution at two different wavelengths. In this embodiment, the detecting member 12 collects two optical signals of the detecting container 2 irradiated by the light source 11, one optical signal being an optical signal before the sample to be detected is added to the detecting container 2, that is, an optical signal when the detecting container 2 is provided with only the diluent and is irradiated by the light source 11 when no blood is provided; the other optical signal is an optical signal when the sample to be detected is added into the detection container 2 and is uniformly mixed by the mixing module 3 and then irradiated by the light source 11, namely, an optical signal when the blood in the detection container 2 is uniformly mixed by the mixing module 3 and then irradiated by the light source 11. After the two optical signals are collected by the detecting element 12, the two optical signals are processed to obtain a test result. Wherein, the light source 11 irradiates the detection container 2 and then is divided into two wavelengths of light after being processed by the detection piece 12, and the test result can be obtained by comparing the absorbance of the light with the two wavelengths after the sample to be detected is not added in the detection container 2 and the added sample to be detected is uniformly mixed.

The light source 11 is a direct-insert LED light source, and the specific material of the light source 11 is not limited herein, and is set according to actual production requirements.

Further, the mixing module 3 includes a driving member 31, a magnetic member 32, and a stirring member 33, where the driving member 31 is connected with the magnetic member 32, and the stirring member 33 is disposed in the detection container 2, and the driving member 31 can drive the magnetic member 32 to drive the stirring member 33 to mix the sample to be detected in the detection container 2.

In this embodiment, the mixing module 3 includes a driving member 31, a magnetic member 32, and a stirring member 33, where the driving member 31 is a driving device for driving the magnetic member 32 to move, and the magnetic member 32 can drive the stirring member 33 to stir. Specifically, the driving member 31 is connected with the magnetic member 32, when the driving member 31 works, the driving member 32 moves together, and the stirring member 33 is placed in the detection container 2, and when the magnetic member 32 moves, the magnetic force of the magnetic member 32 can drive the stirring member 33 in the detection container 2 to rotate at a high speed, so that the sample to be detected in the detection container 2 is uniformly mixed in a rotating manner. The driving member 31 is specifically a brushless motor, the magnetic member 32 is a magnet fixedly connected to a motor shaft, and the stirring member 33 is a stirrer. When the brushless motor rotates at a high speed, the magnet on the brushless motor shaft drives the stirrer in the detection container 2 to rotate at a high speed through magnetic force, so that the sample to be detected in the detection container 2 is uniformly rotated and mixed.

Further, the optical system module 1 further includes an elastic member 13, and the elastic member 13 is fixedly connected with the detection container 2.

In this embodiment, the optical system module 1 further includes an elastic member 13, where the elastic member 13 is fixedly connected to the detection container 2, that is, the elastic member 13 is used to fix the detection container 2, so as to prevent the detection container 2 from being driven to shake when the stirring member 33 in the detection container 2 rotates at a high speed. The elastic member 13 is specifically an elastic sheet, and the specific material of the elastic member 13 is not limited herein, and is set according to actual production requirements.

Further, the optical system module 1 further includes a connecting seat 14, a limiting groove is formed in the connecting seat 14, one end of the detecting container 2 is inserted into the limiting groove, one end of the elastic member 13 is connected with the detecting container 2, and the other end is connected with the limiting groove.

In this embodiment, the optical system module 1 further includes a connecting seat 14, a limiting groove is formed in the connecting seat 14, the detection container 2 is placed in the limiting groove, the detection container 2 can be fixedly arranged, the detection container 2 can also be conveniently replaced, one end of the detection container 2 is arranged in the limiting groove, and the other end of the detection container 2 is exposed out of the limiting groove 2, so that a sample to be detected is placed in the detection container 2. Wherein, one end of elastic component 13 is connected with detecting container 2, and the other end is connected with the spacing groove to but fixed connection detects container 2, prevent to detect container 2 shake.

Specifically, the light source 11 and the detecting member 13 are respectively disposed at both sides of the connection base 14 so that the light source 11 irradiates the detecting container 2 placed in the limit groove in the connection base 14, and the detecting member 12 can conveniently receive the light signal of the detecting container 2 irradiated by the light source 11.

Further, the connecting seat 14 is further provided with a first through hole and a second through hole, the first through hole is communicated with the light source 11 and the limit groove so that the light source 11 irradiates the detection container 2, and the second through hole is communicated with the limit groove and the detection piece 12 so that the detection piece 12 receives the light signal irradiated by the detection container 2.

In this embodiment, the connecting piece 14 is further provided with a first through hole and a second through hole, specifically, the first through hole and the second through hole are disposed on the inner wall of the limit groove, so that the first through hole communicates with the limit groove and the light source 11, and the light source 11 can irradiate the detection container 2 in the limit groove through the first through hole; the second through hole is communicated with the limit groove and the detecting piece 12, so that the detecting piece 12 can receive the optical signal after the light source 11 irradiates the detecting container 2.

Further, the optical system comprises a touch screen 4 and a control main board 5, wherein the touch screen 4 is electrically connected with the control main board 5, and the control main board 5 is electrically connected with the optical system module 1 and the blending module 3.

In this embodiment, the carboxyhemoglobin detection apparatus further includes a touch screen 4, various items of the detection apparatus are displayed on the touch screen 4, operations can be performed by performing an option operation on the touch screen 4, and parameters and test results of the detection apparatus can be displayed on the touch screen 4; the control main board 5 is used for controlling the detection device. The control main board 5 is electrically connected with the touch screen 4, and the control main board 5 is also electrically connected with the optical system module 1 and the blending module 3, that is, various items are displayed on the touch screen 4, and when a user selects an item on the touch screen 4, the control main board 5 receives a user instruction and transmits the instruction to the optical system module 1 or the blending module 3 for operation. For example, when the user selects the blending option on the touch screen 4, the control main board 5 transmits the instruction to the blending module 3, and the blending module 3 rotates the sample to be tested in the testing container 2 at a high speed so as to blend the sample to be tested.

Further, the printing device further comprises a printing module 6 and a power supply module 7, and the printing module 6 and the power supply module 7 are electrically connected with the control main board 5.

In this embodiment, the carboxyhemoglobin detection apparatus further includes a printing module 6 and a power supply module 7, the printing module 6 is used for printing the test result of the patient, and the printing module 6 is specifically a printer; the power supply device 7 provides power for the detection device when the detection device cannot be connected to a power supply, and the power supply device 7 is specifically a battery. The printing module 6 and the power supply module 7 are respectively electrically connected with the control main board 5, and the control main board 5 transmits a user instruction to the corresponding module so that the detection device performs corresponding operation.

Further, the optical system module 1, the detection container 2, the blending module 3, the control main board 5, the printing module 6 and the power supply module 7 are all arranged in the shell 8.

In this embodiment, the carboxyhemoglobin detection apparatus further includes a housing 8, the housing 8 has an accommodating space, and an optical system module 1, a detection container 2, a blending module 3, a control device, a printing module 6 and a power supply module 7 are disposed in the accommodating space, and the plurality of modules are all disposed in the housing 8, so that the detection apparatus has the characteristics of miniaturization and portability.

Further, the optical system module further comprises a cover plate 9, wherein the cover plate 9 is arranged on the shell 8 and is positioned close to the optical system module 1; the touch screen 4 is also provided on the housing 8.

In this embodiment, the carboxyhemoglobin detection apparatus further includes a cover plate 9, where the cover plate 9 is disposed on the housing 8, specifically, the cover plate 9 is disposed above the optical system module 1, and can be used for shielding light, so as to prevent the disordered light source from affecting the test result. Wherein the touch screen 4 is also arranged on the shell 8 so as to facilitate the touch screen operation of a user.

Further, the detecting member 12 is a spectrophotometer; the detection container 2 is a disposable cuvette.

In this embodiment, the detector 12 is specifically a spectrophotometer, which can conveniently divide the received light into two wavelengths after processing; the detection container 2 is a disposable cuvette, and particularly a disposable plastic cuvette can be adopted, so that the cost is low, the detection container can be conveniently replaced, and the operation is convenient; and cleaning is not needed, so that the difference of the test results caused by the residual flow paths is avoided.

Further, the specific steps of using the carboxyhemoglobin detection apparatus are as follows:

1. injecting the diluent into a disposable cuvette containing a reducing agent, and then simultaneously collecting absorbance at two wavelengths of 500nm and 550nm through a detection piece 12 as a blank (i.e. standard) of the system, wherein the light source 11 always irradiates the detection container 2;

2. preparation of blood samples: taking 20uL of blood sample by using a 20uL quantitative pipette, and placing the blood sample into a disposable cuvette;

3. starting the mixing module 3, and closing the mixing module 3 after mixing for 10S;

4. after the mixing module 3 stops, 3S, collecting the absorbance of the sample solution at two wavelengths of 500nm and 550nm through the detection piece 12;

5. the instrument calculates by using a formula to obtain the HbCO concentration in the blood sample to be detected, and displays the HbCO concentration on the touch screen 4;

wherein, a test blood sample was prepared by taking 15uL of blood sample and diluting it 130 times with a diluent. According to the above steps, the absorbance A500 and A550 of the sample to be tested at two wavelengths of 500nm and 550nm are obtained, the calculation formula of the content of carboxyhemoglobin is [ HbCO ]% = (9 5745A 500/A550-3.4212) ×100%, and the concentration of HbCO in the sample to be tested [ HbCO ]% is directly displayed on the screen of the touch screen 4 of the instrument after the test.

It should be noted that, in the present disclosure, each embodiment is described in a progressive manner, and each embodiment is mainly described as different from other embodiments, and identical and similar parts between the embodiments are all enough to be referred to each other.

It should also be noted that in the present disclosure, relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.

The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present disclosure. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the utility model. Thus, the present disclosure is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. The utility model provides a carboxyhemoglobin detection apparatus, its characterized in that includes interconnect's optical system module, detection container and mixing module, optical system module includes light source and detection spare, the light source with the detection container sets up relatively and can shine the detection container, mixing module with the detection container is connected and can mix the sample that awaits measuring in the detection container, the detection spare is used for detecting add in the detection container after the mixing the optical signal around the sample that awaits measuring.

2. The carboxyhemoglobin detection apparatus of claim 1, wherein the mixing module comprises a driving member, a magnetic member and a stirring member, the driving member is connected with the magnetic member, the stirring member is disposed in the detection container, and the driving member can drive the magnetic member to drive the stirring member to mix the sample to be detected in the detection container.

3. The carboxyhemoglobin detection apparatus of claim 1, wherein the optical system module further comprises an elastic member fixedly connected to the detection container.

4. The carboxyhemoglobin detection apparatus of claim 3, wherein the optical system module further comprises a connection seat, a limit groove is formed in the connection seat, one end of the detection container is inserted into the limit groove, one end of the elastic member is connected with the detection container, and the other end of the elastic member is connected with the limit groove.

5. The carboxyhemoglobin detection apparatus of claim 4, wherein the connection base is further provided with a first through hole and a second through hole, the first through hole is communicated with the light source and the limit groove so that the light source irradiates the detection container, and the second through hole is communicated with the limit groove and the detection member so that the detection member receives an irradiated light signal of the detection container.

6. The carboxyhemoglobin detection apparatus of claim 1, further comprising a touch screen and a control motherboard, wherein the touch screen is electrically connected to the control motherboard, and the control motherboard is further electrically connected to the optical system module and the blending module.

7. The carboxyhemoglobin detection apparatus of claim 6, further comprising a printing module and a power module, both of which are electrically connected to the control motherboard.

8. The carboxyhemoglobin detection apparatus of claim 7, further comprising a housing, wherein the optical system module, the detection container, the blending module, and the control motherboard, the printing module, and the power supply module are all disposed in the housing.

9. The carboxyhemoglobin detection apparatus of claim 8, further comprising a cover plate disposed on the housing at a location proximate the optical system module; the touch screen is also arranged on the shell.

10. The carboxyhemoglobin detection apparatus of claim 1, wherein the detection member is a spectrophotometer; the detection container is a disposable cuvette.