WO2015172653A1

WO2015172653A1 - Illumination device and urine formed element analyzer

Info

Publication number: WO2015172653A1
Application number: PCT/CN2015/077650
Authority: WO
Inventors: 王宏良; 包永挺
Original assignee: 科宝智慧医疗科技（上海）有限公司
Priority date: 2014-05-16
Filing date: 2015-04-28
Publication date: 2015-11-19
Also published as: CN105090810A

Abstract

Provided are an illumination device and a urine formed element analyzer. The illumination device comprises a light source (100) and a light uniformizing element (200), wherein the light source (100) is at least partially embedded in the light uniformizing element (200). The urine formed element analyzer comprises a liquid injection system, a transmission system, an optical system and a processing system. The illumination device in the optical system comprises a light source (100) and a light uniformizing element (200), wherein the light source (100) is at least partially embedded in the light uniformizing element (200). By arranging the light uniformizing element (200) matching the light source (100), the illumination device enables emitted light to be more uniform. A pair of lenses (301, 302) are also added in a light path to increase the illumination intensity, thus improving the utilization rate of light emitted by the light source (100). In this way, the power of the light source (100) in the urine formed element analyzer can be smaller, therefore, on the one hand, costs and energy consumption are reduced, and on the other hand, the problem of heat dissipation of the light source (100) is eliminated, so that the service life of the light source (100) can be longer, and the stability thereof can also be better, thereby effectively improving the accuracy and stability of device inspection finally.

Description

Lighting device and urine forming component analyzer

Technical field

The invention relates to the technical field of liquid analysis, in particular to a lighting device and a urine forming component analyzer.

Background technique

In the fields of life sciences, medical and health, food and environmental protection, it is often necessary to analyze the composition of liquids, especially liquids. There are various methods for analyzing liquids, generally including analysis, separation and detection of liquid samples, such as separation of protein peptides in the life sciences, analysis of beverage components in the food field, research on pharmaceutical ingredients in the pharmaceutical field, and health care. Field analysis of such as urine, plasma and serum body fluids, etc.

Optical detection is a commonly used liquid analysis method. It is used to observe liquids through optical instruments, such as microscopes, to obtain information on the composition of liquids, and is particularly suitable for analysis of body fluids in the medical field. There are many prior art automated detection devices for optically analyzing liquids, such as urine. Such as US patents US5699794 'Apparatus for Automated Urine Sediment Sample Handling' The disclosed automatic urine forming component analyzer comprises a liquid injection system, a transmission system, an optical system and a processing system. The liquid injection system respectively fills each urine sample to be analyzed into each analysis container (counting pool), and the transmission system will be completed. The respective analysis containers filled with the liquid are sequentially transferred to the detection position, and the optical system illuminates the analysis container and acquires formed images such as red blood cells, white blood cells, white blood cell masses, and transparent tube types, and the processing system automatically analyzes the acquired images and outputs the images. Test Report. In the automatic urine forming component analyzer, the optical system includes an illumination device, a condenser lens, an objective lens, and a camera, wherein the illumination device and the condenser lens are distributed on one side of the analysis container to be detected, and the objective lens and the camera are distributed on the other side. Upon detection, light emitted from the illumination device is focused by a converging lens, passed through an analysis container, imaged by an objective lens, and acquired by a camera. Patent WO99/41596 'Automatic Test Strip Analyser Apparatus' In the disclosed automatic device, the illuminating device and the condensing lens are distributed on the same side of the detected analysis container. When detecting, the light emitted from the illuminating device is focused by the lens and irradiated to the analysis container and reflected, and the reflected light is imaged through the objective lens. And by The CCD gets the image.

In fact, before optical inspection is not automated, it is performed by human eyes through a microscope or by integrating CCD The microscope of the chip acquires a high-magnification image and sends it to the image processing software for processing to obtain the detection result. Therefore, the optical systems of these automatic detection devices that automatically perform optical detection are directly transplanted into the optical system of the microscope, and the optical of the microscope The system is the same or basically the same. In particular, the illumination device in the optical system includes the light source and the aperture and the illumination device for the microscope. / Optical components such as lenses. The light source may be a light emitting device such as a halogen lamp or an LED. For example, there are generally two types of illumination devices for the optical system of the automatic analysis device for which urine is currently formed. One type is as shown in FIG. The illumination device shown comprises an LED lamp 1 and a convex lens 2, wherein the LED lamp 1 is arranged at the focus of the convex lens 2, and the light emitted by the LED lamp 1 passes through the convex lens 2 After forming a parallel beam, the parallel beam is used as an analysis beam or an optical beam to be used as an analysis beam; the other is an illumination device as shown in FIG. 2, which includes an LED lamp 1 and a concave mirror 3, wherein The LED light 1 is placed at the focus of the concave mirror 3, and the light emitted by the LED light 1 passes through the concave mirror 3 After the reflection, a parallel beam is formed, and the parallel beam is used as an analysis beam or an aperture beam as an analysis beam.

However, it is not entirely appropriate to transplant the optical system of the microscope directly to the automatic inspection equipment for optical inspection. Preferably, the test requirements and the design requirements of the automatic inspection equipment should also be considered.

When urine is formed, the automatic detection equipment only needs to obtain the diameter of the field of view on the sample not exceeding 1mm. The image, but its processing system has high requirements on the accuracy of the image in order to obtain accurate detection results. One of the requirements is the stability and uniformity of illumination. In order to meet this requirement, the existing illuminating device in the optical system of the urine forming automatic detecting device is still a commonly used microscope lighting device, using a halogen lamp or LED The beam is concentrated by the lens, and the stray light at the edge of the beam is removed by the pupil to obtain a stable and uniform analysis beam for illumination on the analysis container. The conventional lighting device consumes a large amount of power, and the heat of the light source is also large, so the heat dissipation problem of the device must be considered, for example, adding a fan to the device, thereby increasing the production cost of the device; and, if a halogen lamp is used as the light source, The service life is very short, usually only a few hundred hours, and the bulb needs to be replaced frequently. In addition, in order to obtain uniform illumination, the conventional illumination device uses only a pupil having a small aperture, whereby the utilization ratio of the light source (i.e., the ratio of the portion of the light emitted by the light source to the analysis container) )very low.

Patent (application number: WO2001001109) 'Device for Automatically Analysing and Counting Objects and Data Processing Method' In the disclosed automatic analysis counter, the optical system includes a lighting device, a CCD And a magnifying lens. Wherein, the illumination device is composed of a light generator and an optical fiber, and the optical fiber confines the light emitted by the light generator to a suitable diameter and conducts to the analysis container to illuminate the analysis container. In addition, the Chinese patent (application number: 201310341358.6 ) 'Double-tube microscope device for urinary sediment detection equipment' also discloses the use of fiber optics to LED The emitted light is constrained to a suitable diameter and conducted to the analytical vessel to illuminate the analytical container. Since the end face of the optical fiber is small, in order to obtain a larger illumination intensity and improve the luminous efficiency of the light source, it is generally required to add a lens collecting light source at the incident end thereof, but the uniformity of illumination of the exit end of the optical fiber is deteriorated. In fact, the brightness of the spot in the exit end of the fiber is relatively high, the periphery is weak, and the uniformity of illumination is poor.

Therefore, those skilled in the art are working to develop a lighting device, The problem of low luminous efficiency of the light source in the prior art described above is solved, and at the same time, the stability and uniformity of the analysis beam are ensured, and a urine forming component analyzer is developed, in which the lighting device is applied.

Summary of the invention

In view of the above-mentioned drawbacks of the prior art, the technical problem to be solved by the present invention is to design a lighting device and apply it to a urine forming component analyzer capable of automatically performing urine forming analysis, and to improve the light source by using and rationally arranging the light homogenizing elements. The luminescence utilization rate and a stable, uniform beam for analysis.

In order to achieve the above object, the present invention provides A lighting device comprising a light source, further comprising a light homogenizing element, the light source being at least partially embedded in the light homogenizing element.

Further, the light homogenizing element has a straight uniform strip shape with a central axis of symmetry; the light homogenizing element extends along the central axis of symmetry; and light emitted by the light source occurs in the light homogenizing element Secondary reflection and / or total reflection, the exiting light exits the light homogenizing element in a direction parallel to the central axis of symmetry.

Further, the light homogenizing element includes a first end portion and a second end portion, the light source is disposed at the first end portion, and a light emitting surface of the light homogenizing element is on the second end portion.

Optionally, the light homogenizing element is solid, having a groove at the first end; the light source is received in the groove; light emitted by the light source is in the light homogenizing element Multiple reflections occur inside and / Or total reflection.

Further, the cross section of the light homogenizing element is a regular polygon or a circle.

Further, the cross section of the light homogenizing element is a regular quadrangle.

Optionally, the light homogenizing element is hollow, having a cavity; the light source is received in the cavity; a central axis of symmetry of the light homogenizing element is a central axis of symmetry of the cavity; The wall of the cavity is a reflective surface, and light emitted by the source is reflected multiple times within the cavity.

Further, the cross section of the cavity is a regular polygon or a circle.

Further, the cross section of the cavity is a regular quadrilateral.

Further, the light source is a halogen bulb or an LED bulb, the halogen bulb or LED The light emitting portion of the bulb faces the second end.

The invention also provides a a urine forming component analyzer comprising an infusion system, a transmission system, an optical system, and a processing system, the infusion system loading a urine sample in an analysis container; the transmission system transmitting the analysis container to a detection position The optical system includes an illumination device, an objective lens, and an image acquisition device, the illumination device including a light source to illuminate the analysis container, the image acquisition device acquiring an image of the urine sample in the analysis container, The processing system analyzes the image and outputs an analysis result of urine forming components of the urine sample;

Characterized in that the illumination device further comprises a light homogenizing element, the light source being at least partially embedded in the light homogenizing element.

Further, the light homogenizing element has a straight strip shape and has a central symmetry axis; Extending along a central axis of symmetry thereof; light emitted by the light source undergoes multiple reflections and/or total reflections within the light homogenizing element, the exiting light exiting the light homogenizing element in a direction parallel to the central axis of symmetry .

Optionally, the light homogenizing element is solid with a groove at the first end; the light source is received within the groove.

Optionally, the light homogenizing element is hollow, having a cavity; the light source is received within the cavity; The central axis of symmetry of the light homogenizing element is the central axis of symmetry of the cavity; the wall of the cavity is a reflecting surface, and light emitted by the light source is reflected multiple times within the cavity.

Further, the cross section of the cavity is a regular polygon or a circle.

Further, the cross section of the cavity is a regular quadrangle.

Optionally, the objective lens and the image acquisition device are disposed below the detection position, and the objective lens faces the analysis container at the detection position.

Further, the illumination device is disposed above the detection position, the exiting light illuminates the analysis container at the detection position and passes through the analysis container to form transmitted light, and the transmitted light passes through the The objective lens is then imaged on the photosensitive element of the image acquisition device.

Optionally, the objective lens, the image acquisition device and the illumination device are both disposed above the detection position, and the emitted light illuminates the analysis container at the detection position and is reflected by the analysis container To form reflected light that is imaged on the photosensitive element of the image capturing device after passing through the objective lens.

Further, the illumination device further includes a lens disposed on an optical path of the outgoing light from the light homogenizing element to the detection position.

Further, the number of the lenses is two, and the two lenses have the same geometric parameters and optical parameters. The two lenses are symmetrical about their median plane; the median plane is perpendicular to the main optical axes of the two lenses and the distance to the two lenses is equal.

Further, the illumination device further includes one or more apertures disposed between the two lenses.

Further, the illumination device further includes a reflective element disposed on an optical path of the outgoing light from the light homogenizing element to the lens, or disposed from the lens to the detection The light path between the locations of the outgoing light.

Further, the reflective element is a plane mirror or a reflective prism.

Further, the photosensitive element is a CCD or a CMOS.

Further, the image acquisition device is a CCD camera or a CMOS camera.

In a preferred embodiment of the present invention, there is provided an illumination device comprising an LED bulb, a light homogenizing element, a pair of lenses and a reflective prism, wherein the light emitted by the LED bulb passes through the light homogenizing element, a pair of lenses and Reflective prism. Wherein, the light homogenizing element is a hollow homogenizing rod, and the inner cavity has a regular quadrangle in cross section. The LED bulb is embedded in the light homogenizing element at one end of the light homogenizing element, and the light emitted by the LED is repeatedly reflected or multiple times reflected and totally reflected in the light homogenizing element, and parallel to the light homogenizing element from the other end of the light homogenizing element. The direction of the central axis of symmetry leaves the light homogenizing element. In the preferred embodiment, there is also provided a urine forming component analyzer, wherein the illumination device and the objective lens are respectively disposed on both sides of the analysis container, and the analysis light beam from the illumination device passes through the analysis container and the objective lens in the image. Imaging is obtained on the photosensitive element of the acquisition device. The illuminating device is composed of an LED bulb, a shimming element, a pair of lenses and a reflecting prism. The light emitted by the LED bulb passes through the shimming element, a pair of lenses and a reflecting prism, and then illuminates the analysis container at the detecting position. Wherein, the light homogenizing element is a hollow homogenizing rod, and the inner cavity has a regular quadrangle in cross section. The LED bulb is embedded in the homogenizing element at one end of the homogenizing element, and the emitted light is subjected to multiple total reflection or reflection and total reflection in the homogenizing element, and is symmetric from the other end of the homogenizing element parallel to the center of the uniforming element. The direction of the axis leaves the light homogenizing element. The pair of lenses have the same geometric and optical parameters, which are arranged symmetrically about their median plane, their primary optical axes being arranged to coincide with the optical path of the exiting light of the light homogenizing element. The reflective prism deflects the beam exiting the pair of lenses by 90 ^o to normal incidence of the analysis vessel. The image acquisition device is a CCD camera in which the photosensitive element is a CCD.

It can be seen that the illumination device of the present invention cooperates with the light source by using a light homogenizing element. Allowing most of the light emitted from the source to enter the homogenizing element and undergo multiple reflections in the homogenizing element / After total reflection, a large-angle beam portion is filtered out to become a uniform and stable beam to be used as an analysis beam, thereby improving the light-emitting efficiency of the light source. In addition, the use of a pair of identical lenses for concentrating in the illumination device greatly reduces the type of lens lens used on the optical path, thereby effectively reducing the cost, and the concentrating effect thereof can greatly improve the light-emitting utilization of the light source. The urine-forming component analyzer of the present invention makes use of a lower power by using the illumination device of the present invention having a high light source utilization efficiency LED As a light source, it can also meet the detection requirements, thus reducing the cost and energy consumption on the one hand, and the heat generated by the light source is smaller on the other hand, and the heat sink can be omitted in the detection device. Again, by using a reflective element to change the optical path in the illumination device, the overall arrangement of the urine forming component analyzer can be made more flexible in space, and the overall machine space can be effectively saved.

The concept, the specific structure and the technical effects of the present invention will be further described in conjunction with the accompanying drawings in order to fully understand the objects, features and effects of the invention.

DRAWINGS

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 is a schematic illustration of a prior art illumination device in an automated analytical device for urine forming.

2 is a schematic illustration of a lighting device in another prior art automated analysis device for urine forming.

Fig. 3 shows an optical system of the urine forming component analyzer of the present invention in a preferred embodiment.

Fig. 4 is a schematic view showing a longitudinal section of a structure of a light homogenizing element used in the illumination device of the optical system of Fig. 3.

Figure 5 is a schematic illustration of a cross section of the light homogenizing element shown in Figure 4.

Fig. 6 is a schematic view showing a longitudinal section of another structure of a light homogenizing element used in the illumination device of the optical system of Fig. 3.

Figure 7 is a schematic illustration of a cross section of the light homogenizing element shown in Figure 6.

Fig. 8 is a schematic view showing a longitudinal section of a third structure of the light homogenizing element.

Figure 9 is a schematic illustration of a cross section of the light homogenizing element shown in Figure 8.

Fig. 10 is a schematic view showing a longitudinal section of a fourth structure of the light homogenizing element.

Figure 11 is a schematic illustration of a cross section of the light homogenizing element shown at Figure 10 at a first end.

Figure 12 shows a light homogenizing element with a reflective layer on the end face at the first end.

Figure 13 shows a light homogenizing element provided with an annular concave mirror at the first end.

detailed description

In a preferred embodiment of the present invention, a The illuminating device and the urine forming component analyzer are applied to the urinary component forming analyzer, but it should be noted that the illuminating device of the present invention can also be applied to illumination of other devices.

The urine forming component analyzer of the present invention includes a liquid injection system, a transmission system, an optical system, and a processing system. The liquid injection system respectively fills each urine sample to be analyzed in the analysis container 501 as shown in FIG. In each of the analysis containers; the transmission system sequentially transfers the respective analysis containers that complete the filling of the liquid to the detection position, and the detection position in the embodiment is at the sample stage 500. The optical system illuminates the analysis container and obtains an image of the formed therein such as red blood cells, white blood cells, white blood cell masses, and transparent tube types. As shown in FIG. 3, the optical system includes a lighting device and an objective lens 600. , a reflective element 700 and an image acquisition device, the illumination device comprising an LED bulb 100, a light homogenizing element 200, a lens 301, a lens 302 and a reflective element 400; image imaging On the photosensitive element 800 of the image acquisition device, the photosensitive element may be a CCD or a CMOS; the processing system automatically analyzes the acquired image and outputs a detection report.

In the present embodiment, the illumination device is distributed on one side of the detected analysis container 501, the objective lens 600, the reflection member 700, and the photosensitive member. 800 is distributed on the other side of the assay container 501 being tested, wherein the photosensitive element 800 is CMOS. Specifically, in the embodiment, the sample stage 500 is a platform arranged horizontally, and the analysis container The 501 is placed flat on the sample stage 500, the illumination device is distributed above the analysis container 501, and the objective lens 600, the reflective element 700, and the photosensitive element 800 are distributed in the analysis container 501. Below. At the time of detection, light emitted from the illumination device illuminates the analysis container 501 and passes through the analysis container 501 to form transmitted light which passes through the objective lens 600 and the reflection member 700 after the photosensitive member The target surface of 800 is imaged, thereby obtaining a formed image of a sample such as red blood cells, white blood cells, white blood cell clusters, and transparent tube type in the sample in the analysis container 501.

It should be noted that since the light path can be adjusted by using the reflective element, some of the components in the illumination device may not be disposed on the sample stage 500. The upper surface of the upper surface is located above, and some of the objective lens 600, the reflective element 700, and the photosensitive element 800 may not be disposed on the sample stage 500. The lower surface is located below the plane, so in the present technical solution, as long as the element in the illumination device that directly illuminates the analysis container 501 is disposed in the analysis container 501 Above, it is considered that the illuminating device is disposed above the detecting position; likewise, as long as the element that exits the illuminating analysis container 501 directly enters the objective lens 600 and the reflecting member 700 is disposed in the analyzing container Below 501, the objective lens 600 is considered to be positioned below the detection position. In addition, although the sample stage 500 in this embodiment It is placed horizontally, but the 'above' and 'below' here should not be limited to the upper and lower sides in the usual sense. Considering the arrangement of the sample stage and the position of the analysis container relative to the sample stage, where the direction of the incident light of the analysis container is defined as 'downward', the direction of the transmitted light of the analysis container is also 'down', and The direction of the reflected light of the analysis container is 'upward'; thus, above the detection position is a space extending from a plane passing through the incident point of the incident light on the analysis container in a direction opposite to the direction of the incident light, and the lower side of the detection position is from the passage The plane of the transmitted light at the exit point of the analysis container extends in the same direction as the direction of the transmitted light.

This embodiment describes the use of transmitted light imaging of an analytical container, and in other embodiments, the reflected light of the analytical container can also be imaged. At this time, the illumination device and the objective lens are both disposed above the detection position, and the arrangement of the optical path and the component is similar to that of the embodiment, and details are not described herein.

As shown in FIG. 3-5, in this embodiment, a hollow homogenizing rod is used as the light homogenizing element 200, which is a uniform straight strip shape having a first end. 201 and second end portion 202, where 'uniform' means that the cross-section of the portion of the uniform light element 200 between the first end portion 201 to the second end portion 202 that is perpendicular to its central axis of symmetry is the same There is a cavity therein, and the inner wall of the cavity is a reflecting surface. The cavity has a central axis of symmetry, in this embodiment Its cross section is a regular quadrilateral (the cross section here refers to a section perpendicular to its central axis of symmetry). In other embodiments, the cross section of the cavity may also be circular, as shown in Figures 6 and 7 of the light homogenizing element 210, The cross section of the cavity between the first end 201 and the second end 202 is circular; in other embodiments, the cross section of the cavity may be other regular polygons, such as an equilateral triangle, a regular hexagon. Wait. led The bulb 100 is embedded in the cavity at the first end 201 with its light emitting portion facing the second end 201. In this specification, the light-emitting portion of the LED light bulb 100 refers to the LED light bulb 100. Preferably, the light-emitting portion of the LED bulb 100 faces the second end portion 201. The maximum intensity of the light emitted by the LED bulb 100 is directed toward the second end. 201 The direction. Similarly, for illumination devices employing other light sources, such as halogen bulbs, the light source is arranged with its light emitting portion facing the second end such that the direction of propagation of the maximum intensity of the light emitted by the light source is toward the second end. direction.

The light emitted by the LED bulb 100 is reflected multiple times within the cavity and exits the shimming element 200 from the second end 202. That is, in this embodiment, the light exiting surface of the light homogenizing element 200 is at the second end portion 202. Since the light emitted by the LED bulb 100 is in the light homogenizing element 200 Multiple reflections occur inside, and a large angle beam portion is filtered out, and the light emitted from the light homogenizing element 200 is a light beam having good uniformity and stability. Since the LED bulb 100 is embedded in the light homogenizing element 200 Within its range, its luminous efficiency has been effectively improved. Preferably, the inner wall of the cavity has a metal plating film or an optical reflection film to reduce light loss and obtain a high light source utilization efficiency.

In addition, a solid homogenizing rod can be used as the light homogenizing element, as shown in Figures 8 and 9, the light homogenizing element 220 It is a straight strip having a first end 221 and a second end 222. The light homogenizing element 220 has a central axis of symmetry, Its cross section is circular. In other embodiments, the cross section of the solid dodging element may also be a regular polygon. The LED bulb is disposed at the first end portion 221 with its light emitting portion facing the second end portion 222 The emitted light enters the light homogenizing element 220 from the first end portion 221 and multiple times total reflection occurs therein, and finally exits the light homogenizing element 220 from the second end portion 222, that is, the light homogenizing element 220 in this embodiment. The light exiting surface is at the second end 222. Since the light emitted by the LED bulb 100 is totally reflected multiple times in the leveling element 220, the light homogenizing element 220 The outgoing light is a light beam with good uniformity and stability. Preferably, the outer side wall of the light homogenizing element 220 has a metal coating or an optical reflective film to ensure the light homogenizing element 220. The outer sidewalls have better reflective properties, thereby reducing the loss of light therein, thereby increasing the luminous efficiency of the light source.

The light homogenizing elements 230 shown in Figures 10 and 11 are straight elongated with a first end 231 and a second end 232. The cross section is circular. In other embodiments, the cross section may also be a regular polygon. The first end portion 231 of the light homogenizing element 230 is provided for accommodating the LED bulb 100 The groove is used to further improve the light-emitting utilization of the light source. In addition, A metal plating film or an optical reflective film may be disposed on the end surface at the first end of the light homogenizing element to prevent the light beam in the light homogenizing element from partially exiting from the end surface at the first end thereof, thereby further Improve the luminous efficiency of the light source. For example, as shown in Fig. 12, the end face of the first end portion 231 of the light homogenizing element 230 has a metal plating film 233 thereon.

To go further Increasing the luminous efficiency of the light source, and further providing a reflective structure at the first end of the light homogenizing element, the light beam portion of the light source that does not directly enter the light homogenizing element, and the light beam that will be emitted from the first end portion of the light homogenizing element Partially reflected into the light homogenizing element. For example, as shown As shown at 13 , the first end portion 231 of the light homogenizing element 230 is provided with an annular concave mirror 234 through which the light source 100 is embedded by the concave mirror 234.

After the beam leaves the light homogenizing element 200, it passes through the lens 301 and the lens 302 in sequence, and the lens 301 and the lens 302 have The same geometric parameters and optical parameters, ie their size, the refractive index of the material and the surface coating are the same, their intermediate planes are symmetrical, where the median plane is perpendicular to the main optical axis of the two lenses and A plane in which the distances of the two lenses are equal. The main optical axes of the lens 301 and the lens 302 are arranged on the optical path of the outgoing light of the light homogenizing element 200, and the distance between the two is set such that the outgoing light beam of the lens 302 is opposite to the lens 301. The incident beam is convergent to improve the luminous efficiency of the light source. Preferably, after the outgoing light of the light-homogenizing element 200 passes through the lens 301 and the lens 302, the beam diameter is reduced to 1/10 of the original. . In order to ensure the stability of the optical path, the lens 301 and the lens 302 are fixed to the lens barrel 303.

A diaphragm 304 is disposed between the lens 301 and the lens 302, and is integrally formed with the lens barrel 303 or fixed to the lens barrel 303. On. The use of a diaphragm effectively filters out stray light at the edge of the beam, resulting in a more uniform exit beam. In addition, the illumination device in the urine forming component analyzer of the present invention may further include a plurality of apertures disposed on the lens Between 301 and lens 302.

In this embodiment, the light beam leaving the lens 302 is illuminated by the reflective element 400 to illuminate the analysis container 501. In order to ensure the stability of the optical path, the reflective member 400 is also fixed to the lens barrel 303. Reflective element 400 A plane mirror or a reflective prism can be used, and a reflective prism is used in this embodiment. In fact, it is also possible to directly illuminate the analysis container 501 with a light beam leaving the lens 302 without using a reflective element, using a reflective element. 400 Changing the optical path can set the light source, the light-shaping element and the lens in a suitable position in the urine forming analyzer, so that the whole machine arrangement of the urine forming analyzer can be more flexible in space, and can effectively save the whole machine. space. In addition, the reflective element The 400 can also be disposed on the optical path from the light homogenizing element 200 to the lens 301, and a plurality of reflective elements can be used to more effectively save overall space.

The transmitted light exiting the analysis vessel 501 enters the objective lens 600 through the apertures in the sample stage 500, exiting the objective lens 600. The light beam is reflected by the reflective element 700 and imaged on the target surface of the photosensitive element 800. The photosensitive element 800 The image is acquired and transmitted to the processing system of the urine forming component analyzer of the present invention for automatic image processing. Similarly, the reflective element 700 can be a plane mirror or a reflective prism. In this embodiment, a plane mirror is used. Multiple reflective elements can be used to more effectively save overall space.

The above has described in detail the preferred embodiments of the invention. It will be appreciated that many modifications and variations can be made in the present invention without departing from the scope of the invention. Therefore, any technical solution that can be obtained by a person skilled in the art based on the prior art based on the prior art by logic analysis, reasoning or limited experimentation should be within the scope of protection determined by the claims.

Claims

A lighting device comprising a light source, further comprising a light homogenizing element, the light source being at least partially embedded in the light homogenizing element.
The illumination device of claim 1 wherein said light homogenizing element is in the form of a straight strip having a central axis of symmetry; said light homogenizing element extending along said central axis of symmetry; said light source emitting light Multiple reflections and/or total reflections occur within the light homogenizing element, and the exiting light exits the light homogenizing element in a direction parallel to the central axis of symmetry.
The illumination device of claim 2, wherein said light homogenizing element comprises a first end and a second end, said light source being disposed at said first end, said light exiting surface of said light homogenizing element being Said on the second end.
A lighting device according to claim 3, wherein said light homogenizing element is solid, having a groove at said first end; said light source being received within said groove; said light source Light is totally reflected multiple times within the light homogenizing element.
The illumination device of claim 4, wherein the light homogenizing element has a regular polygon or a circular cross section.
A lighting device according to claim 5, wherein said cross section of said light homogenizing element is a regular square.
The illumination device of claim 3 wherein said light homogenizing element is hollow having a cavity; said light source being received within said cavity; said central axis of symmetry of said light homogenizing element being said a central axis of symmetry of the cavity; the wall of the cavity being a reflective surface, the light emitted by the source being reflected multiple times within the cavity.
The illumination device of claim 7, wherein the cavity has a regular polygon or a circular cross section.
The illumination device of claim 8 wherein said cross section of said cavity is a regularogram.
A lighting device according to any of the preceding claims, wherein said light source is a halogen bulb or an LED bulb, the light emitting portion of said halogen bulb or LED bulb facing said second end.
A urine forming component analyzer comprising an infusion system, a transmission system, an optical system, and a processing system, the infusion system loading a urine sample in an analysis container, the transmission system transmitting the analysis container to the detection Positionally, the optical system includes a lighting device, an objective lens, and an image acquiring device; the lighting device includes a light source to illuminate the analysis container, and the image acquiring device acquires an image of the urine sample in the analysis container, The processing system analyzes the image and outputs an analysis result of urine forming components of the urine sample;

Characterized in that the illumination device further comprises a light homogenizing element, the light source being at least partially embedded in the light homogenizing element.
A urine forming component analyzer according to claim 11, wherein said light homogenizing element has a straight strip shape having a central axis of symmetry; said light homogenizing element extends along said central axis of symmetry; said light source Light is reflected multiple times and/or totally reflected within the light homogenizing element, and the exiting light exits the light homogenizing element in a direction parallel to the central axis of symmetry.
A urine formed component analyzer according to claim 12, wherein said light homogenizing element comprises a first end and a second end, said light source being disposed at said first end, said light homogenizing element The light exiting surface is on the second end.
A urine formed component analyzer according to claim 13, wherein said light homogenizing element is solid, having a groove at said first end; said light source being received in said groove; Light emitted by the light source undergoes multiple reflections and/or total reflections within the light homogenizing element.
A urine formed component analyzer according to claim 14, wherein said light homogenizing element has a regular polygon or a circular cross section.
A urine formed component analyzer according to claim 15, wherein said cross section of said light homogenizing element is a regular quadrangle.
A urine formed component analyzer according to claim 13, wherein said light homogenizing element is hollow having a cavity; said light source is housed in said cavity; said central axis of symmetry of said light homogenizing element Is the central axis of symmetry of the cavity; the wall of the cavity is a reflective surface, and light emitted by the light source is reflected multiple times within the cavity.
A urine formed component analyzer according to claim 17, wherein said cross section of said cavity is a regular polygon or a circle.
A urine formed component analyzer according to claim 18, wherein said cross section of said cavity is a regular quadrangle.
A urine formed component analyzer according to claim 13, wherein said light source is a halogen bulb or an LED bulb, and a light emitting portion of said halogen bulb or LED bulb faces said second end.
A urine formed component analyzer according to claim 20, wherein said objective lens is disposed below said detection position, said objective lens being opposed to said analysis container at said detection position.
A urine forming component analyzer according to claim 21, wherein said illuminating means is disposed above said detecting position, said outgoing light illuminating said analysis container at said detecting position and passing through said analyzing container To form transmitted light, which is imaged on the photosensitive element of the image capturing device after passing through the objective lens.
A urine formed component analyzer according to claim 20, wherein said objective lens and said illumination means are disposed above said detection position, said outgoing light illuminating said analysis container at said detection position and The analysis container reflects to form reflected light that is imaged on the photosensitive element of the image acquisition device after passing through the objective lens.
A urine forming component analyzer according to claim 22 or 23, wherein said illuminating device further comprises a lens, said lens being disposed at said emitted light between said shimming member and said detecting position On the road.
A urine formed component analyzer according to claim 24, wherein said lens has two numbers, said two lenses having the same geometric parameter and optical parameter, said two lenses being symmetric about their intermediate planes The intermediate plane is perpendicular to the main optical axes of the two lenses and the distance to the two lenses is equal.
A urine formed component analyzer according to claim 25, wherein said illumination means further comprises one or more apertures disposed between said two lenses.
A urine formed component analyzer according to claim 25 or 26, wherein said illumination device further comprises a reflective member disposed at said outgoing light from said light homogenizing member to said lens On the optical path, or on the optical path of the outgoing light from the lens to the detection position.
A urine formed component analyzer according to claim 27, wherein said reflecting member is a plane mirror or a reflecting prism.
The urine formed component analyzer according to claim 28, wherein said photosensitive member is CCD or CMOS.
A urine formed component analyzer according to claim 29, wherein said image acquisition means is a CCD camera or a CMOS camera.