CN108014267A - A kind of liter is immunized, reducing blood lipid, the Chinese medicine composition and preparation method thereof for protecting heart and brain - Google Patents
A kind of liter is immunized, reducing blood lipid, the Chinese medicine composition and preparation method thereof for protecting heart and brain Download PDFInfo
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Abstract
Be immunized the invention discloses a kind of liter, reducing blood lipid, protect heart and brain Chinese medicine composition.The Chinese medicine composition component includes radix astragali, Radix Salviae Miltiorrhizae, pseudo-ginseng, ginkgo leaf, pueraria lobata, emblic, radix polygonati officinalis, using " four-way is theoretical ", tonifying Qi dissolving stasis（Strengthen immunity, reduce blood fat）Two approach acts at the same time, to cardiovascular and cerebrovascular disease, such as hyperlipidemia, low density lipoprotein cholesterol（HDL‑‑C）Mass formed by blood stasis, deficiency myocardial blood supply, cerebral insufficiency, immunity function decline, other symptoms（Insomnia, weak, anorexia, stomachache, vascular hypertension etc.）Etc. there is relatively good therapeuticing and health effect, having reached correction does not stay evil effect, available for cardiovascular and cerebrovascular disease secondary prevention.
Description
Technical field
The present invention relates to tcm field, more particularly to the Chinese medicine composition under a kind of unique instruction of Chinese Medicine theory and its
Preparation method, in particular to a kind of liter are immunized, reducing blood lipid, the Chinese medicine composition and preparation method thereof for protecting heart and brain.
Background technology
Angiocardiopathy mainly includes：Hyperlipemia, hypertension, heart disease（Coronary heart disease, pulmonary heart disease, Senile valve disease, the heart
Restrain not normal）Deng, its early symptom is shown as：1, regular nervous, shortness of breath is uncomfortable in chest, even tingle, disappears after 1-2 seconds general
Lose；2, palpitating speed when exciting, chest has significant discomfort sense, disappears a little while；3, precordialgia or left part are put when dry weight is lived
Penetrating property is felt numb sore；Feel very tried when doing light work, and asthma uncomfortable in chest；4, after meal breastbone suppress swollen severe, emit cold sweat sometimes；Sleep
Shi Jingchang is uncomfortable in chest to feel bad, and cannot lie low；The time is slightly long on foot or just asthma uncomfortable in chest when speed is slightly fast, palpitating speed.
Cerebrovascular disease includes：Ischemic cerebrovascular disease, hemorrhagic cerebrovascular disease, in addition expert hypertensive encephalopathy is also included in
Its early symptom of cerebrovascular disease category has：1, regular headache is dizzy, tinnitus；Slowness of thinking, slow in reacting, memory subtracts
Move back, it is absent minded；2, poor sleeping quality, dreaminess, feels very tired after waking up；3, finger tip or finger are numb or shake
Quiver；Legs become numb is felt once in a while, needs to press or pat just to get better repeatedly to turn；4, the numb hair of tongue is stiff, and it is not agile to speak；The corners of the mouth is normal
Feel to moisten, or lose control of and slobber.
Cardiovascular and cerebrovascular disease is a kind of serious threat mankind, particularly the common disease of more than 50 years old middle-aged and elderly people's health, i.e.,
Make, using treatment means most advanced, perfect at present, can still have more than 50% cerebrovas-cularaccident survivor life cannot completely certainly
Reason！The number that cardiovascular and cerebrovascular disease is died of in the whole world every year is up to 15,000,000 people, and it is the first to occupy the various causes of the death.Cardiovascular and cerebrovascular disease is
As " the noiseless demon " of the highest number one killer of human death's cause of disease, and health of people！Cardiovascular and cerebrovascular disease has " morbidity
Rate is high, disability rate is high, the death rate is high, high recurrence rate, and complication is more "-" more than four high one " the characteristics of, at present, China's heart and brain blood
Pipe Disease alreadys exceed 2.7 hundred million people！China dies of nearly 3,000,000 people of cardiovascular and cerebrovascular disease every year, and it is annual total dead to account for our states
Die the 51% of the cause of disease.And the 75% different degrees of disability of patient to survive, 40% weight are residual！China's patient with cerebral apoplexy goes out
The recurrence rate of First Year is 30% after institute, and the high recurrence rate of the 5th year is up to 59%.And secondary prevention is made the preferable U.S. is only
10%.Since China's medical insurance covers a people group of mean people, the recurrence rate of patient with cerebral apoplexy will be higher by 1 times compared with international average is horizontal！
The atherosclerotic lesion of cardiocerebrovasculaevents events is caused generally to be begun to from adolescence, the progress and hair of lesion
Make trouble part except with age, gender and inherent cause（These are immutable）Have outside the Pass, depending primarily upon to whether there is causes disease to be sent out
Raw and development hazards, these hazards mainly include hypertension, blood fat disorder, carbohydrate metabolism disturbance and smoking.These
Cause the hazards that atherosclerotic lesion is in progress different from age, gender and inherent cause, can be by appropriate
Intervention means change, and in short, control these hazards can to delay, controls or even prevention of arterial atherosclerotic lesion
Occurrence and development, prevent cardiocerebrovasculaevents events.The prevention of cardiovascular and cerebrovascular disease includes primary prevention and secondary prevention, primary prevention
It is that disease-free diseases prevention occurs, secondary prevention is to prevent re-pull after illness, and no event prevents the generation of event in other words, has and gets over
Part prevents that event occurs again.
In general, the drug therapy of cardiovascular and cerebrovascular disease, understands according to different cardiovascular and cerebrovascular diseases, such as：It is hyperlipidemia, low
Density lipoprotein-cholesterol（HDL--C）Mass formed by blood stasis, deficiency myocardial blood supply, cerebral insufficiency, immunity function decline, other symptoms
（Insomnia, weak, anorexia, stomachache, vascular hypertension etc.）Targetedly medicine is given, with relief of symptoms, improves prognosis,
Prevent complication.Judgement for various cardiovascular and cerebrovascular diseases, general patient is difficult to be judged, in terms of cardiovascular and cerebrovascular disease
Medicine is even more numerous, can not make choice application, and to reach secondary prevention, and being more for patient can not be complete
Into.
My company by theory of traditional Chinese medical science for many years derive and drug test, find the general character pathology base of cardiovascular and cerebrovascular disease
Plinth is：1st, the stagnation of the circulation of vital energy；2nd, phlegm is turbid.According to pathologic basis, determine the rules for the treatment of for " four-way is theoretical "：Gas leads to, blood leads to, the heart leads to, brain leads to.It is modern
Medical research shows, traditional Chinese medical science tonifying Qi, for mainly improve immunity.Eliminating the phlegm is turbid, is primarily directed to reduce blood fat.
Modern medicine does not have the saying of tonifying Qi, the method that immunity is only improved with the medicine of albumin, thymosin extrasin etc.
In fact this with tonifying Qi, some are identical, if not having tired out gas consumption, we would not insomnia and dreamful sleep, nervous, shortness of breath, also would not be easy
Suffer from a heart complaint；Consolidating for gas is not taken the photograph, and menstruation will shift to an earlier date, and amount can also increase.How gas can not enable blood metaplasia, menstruation again
How not delay again, measure and lack, the women of nursing period, due to bearing children, gas consumption obtains most severe, has also lacked consolidating for gas and has taken the photograph
And lochiorrhagia, uterus can not restore for a long time.Milk is also qi and blood, and the people of the deficiency of vital energy, the raw material deficiency of gas, is not excessive
Breast, is exactly to lose breast, such a example, act is unclear, also says endless.Qi-tonifying drug have bushing gas, tonifying lung gas, enriching spleen-QI, kidney tonifying gas,
A variety of sayings of tonifying primordial Qi, experienced doctor are also to have very much feature when with Chinese medicine, nor a herb just can handle
All internal organs gas are all mended.For example have a high fever, perform an operation, bearing child, for a long time with antibiotic, chemicotherapy etc., such case
Patient all sap one's vitality, kidney qi is lost long, this when can take the ginseng to reinforce vital energy, can eat the lozenge of ginseng,
Ginseng tea can be steeped to drink, body can be made to restore early, but when with ginseng, it is preferably to drink water more, so understand good absorbing, be not easy
Fire.Usually we with ginseng mend body when, once occur in the mouth long ulcer, be hard and dry, burning sensation during urination, or life it is flat
Peach body is scorching, even nosebleed, this is to mend too, has to be discontinued.
The stagnation of the circulation of vital energy refer to internal organs, QI of channels and collaterals retardance it is not smooth.Can be because of diet perverse trend, or seven feelings pent-ups, or general deficiency of qi institute is not transported
Cause.There are different symptoms with the stagnant part of institute.In spleen, then stomach receives reduction to the stagnation of the circulation of vital energy, turgor pain;The stagnation of the circulation of vital energy is in liver then liver-qi perversion, the side of body
Pain irritability;Then lung qi is unclear in lung for the stagnation of the circulation of vital energy, and abundant expectoration is breathed with cough.The stagnation of the circulation of vital energy in channels and collaterals then this through circulation route region of interest pain or movement
Obstacle, or corresponding symptom.The stagnation of the circulation of vital energy, which is exaggerated, to be promoted powerless and causes blood stasis, forms the deficiency of vital energy and blood stasis and the pathological change deposited.Grab
Firmly main problem, " effecting a permanent cure " --- tonifying Qi are ventilated.
Phlegm is turbid, the angle analysis of the life science including modern medicine, and also the turbid concept of phlegm, the turbid essence of phlegm are not
What, that is, generation phlegm is turbid, the present day schemes of phlegm disease occurs how, contemporary medical practice, makes many doctors notice that phlegm is turbid
With the relation of Anomalous lipid metablism.Which type actually either in hyperlipidemia, first directly increases plasma viscosity, makes lipid
It is sunken on vascular wall and to generate phlegm turbid;Second the axis stream component in blood vessel is can be done directly on, causes the formation of small thrombus, and
Cause phlegm and blood stasis.For blood in flow process, unstable, component the change of its characteristic, influences its speed, flow direction, mode, journey
The change of degree and property, may be related with " it is turbid that body fluid Bu Xunchang roads become phlegm ".Hematoblastic aggregation, adhesiveness and release work(
When can be sexually revised in pathology, the normal fluidised form of blood is just necessarily affected;Packed cell volume is excessive, aggregation enhancing, deformability
Lowly, cause blood viscosity to increase, make blood operation not normal.Due to blood viscosity increase, obstacle also occurs for microcirculation, or even occurs micro-
Thrombus, this is the turbid result formed in hemorheology of phlegm.We catch another key issue, " effecting a permanent cure " --- dispel turbid logical
Blood.
According to " four-way " rules for the treatment of, we have drafted prescription：Monarch drug in a prescription：Radix astragali, Radix Salviae Miltiorrhizae；Ministerial drug：Pseudo-ginseng, ginkgo leaf.
Radix astragali is also named " astragalus ", and the traditional Chinese medical science is considered famous tonifying Qi good medicine, has strong effect to human body.Warm-natured, taste
It is sweet, there are tonifying Qi and lifting yang, strengthening exterior and reducing sweat, apocenosis myogenic, the function of swelling diuretic.Cure mainly physically weak spontaneous perspiration, overstrain internal injury, loose stool abdomen
Rush down, deficiency of vital energy edema and ulcer carbuncle etc..The operation of blood be unable to do without the impetus of gas.The operation of blood depends on the motive, lung
The promotion of gas and the catharsis tune of irritability are smooth, and therefore, gas fills Sheng, and QI movement being in harmonious way, then blood, the normal operation of blood are able to gas row
Ensure.Gas can carry efficiency and reach an internal organs, therefore gas abundance is the precondition of human body blood forming organ normal work.If
Anemia damage or run it is not normal may result in various discomforts, such as insomnia, forgetful, irritated, palpitation with fear, stupor etc..If things go on like this
It will cause more serious disease.
Radix Salviae Miltiorrhizae has promoting blood circulation, cool blood to disappear carbuncle, the effect of nourishing blood and tranquilization.Dysmenorrhoea, amenorrhoea, abdominal mass, dysphoria with smothery sensation can be controlled
The diseases such as uneasiness, carbuncle sore tumefacting virus.Coronary disease and angina pectoris is relatively specific for, cerebrovascular sufferer, hypertension, thrombotic sufferer, menstruation is not
Reconcile all kinds of blood-stasis syndromes.Radix Salviae Miltiorrhizae is the same as four things, hepatitis hypochondriac pain coronary heart disease simply.Radix Salviae Miltiorrhizae bitter cold nature, removing blood stasis for promoting tissue regeneration collapse band
Under.Broken disease is vexed full except lump in the abdomen, and irregular menstruation is passed through difficulty.
Radix astragali tonifying Qi, gas energy promoting circulation of blood, carries efficiency and reaches each internal organs, is each organ normal work of human body, promotes cyclic system
System cardiac, systemic circulation, contracting muscles involved by partial circulating recover the normal rhythm and pace of moving things and power.Radix Salviae Miltiorrhizae dissolving stasis, reduces blood plasma
Viscosity, makes the turbid reduction of the phlegm on vascular wall and in blood；Axis stream component in vasoactive, reduces the formation of small thrombus.
The two is monarch, and collective effect, reaches the organic and functional recovery of cardiovascular system.
Pseudo-ginseng, dissipate stasis of blood hemostasis, detumescence ding-tong.And with reparation injury of blood vessel, analgesic effect；Ginkgo leaf, hinders for hemostasis
Network, chest impediment and cardialgia, hemiplegia, deficiency syndrome of the lung cough and asthma, hyperlipidemia.Due to cardiovascular and cerebrovascular disease long-term existence, anemia damage can be produced
Or operation is not normal may result in various discomforts, insomnia, forgetful, irritated, palpitation with fear, stupor etc..Pseudo-ginseng is taken to dissipate the reinforcement of stasis of blood effect
Radix Salviae Miltiorrhizae dissolving stasis effect, and analgesic therapy effect is taken, solve numbness pain symptom caused by cardiovascular and cerebrovascular disease；Take ginkgo leaf, lipid-loweringing is dispelled turbid, is added
Strong Radix Salviae Miltiorrhizae dissolving stasis effect, and analgesic therapy effect is taken, solve numbness pain symptom caused by cardiovascular and cerebrovascular disease.
Radix astragali, Radix Salviae Miltiorrhizae, pseudo-ginseng, ginkgo leaf four traditional Chinese medicine play the effect of gas leads to, blood leads to, the heart leads to, brain is logical altogether, and have to numbness pain bright
Aobvious mitigation.
Recipe determination tables of data
| Prescription one | Prescription two | Prescription three | Prescription four | Prescription five | Prescription six | |
| Radix astragali | 200 | 250 | 300 | 350 | 400 | 450 |
| Radix Salviae Miltiorrhizae | 260 | 240 | 220 | 200 | 180 | 160 |
| Pseudo-ginseng | 210 | 190 | 170 | 150 | 130 | 110 |
| Ginkgo leaf | 160 | 140 | 120 | 100 | 80 | 60 |
| Triglycerides | 80.1% | 80.2% | 85.4% | 83.5% | 82.9% | 83.1% |
| Low-density lipoprotein | 80.4% | 81.4% | 83.5% | 84.1% | 83.4% | 82.6% |
| High-density lipoprotein | 79.5% | 81.8% | 82.9% | 83.2% | 82.1% | 81.7% |
| Deficiency myocardial blood supply | 84.2% | 85.1% | 90.0% | 86.5% | 84.3% | 85.1% |
| Cerebral insufficiency | 84.3% | 86.0% | 88.7% | 86.7% | 85.8% | 82.3% |
| Immune dysfunction | 74.3% | 75.4% | 80.6% | 80.9% | 81.4% | 81.9% |
The effect of two kinds of medicinal materials of tonifying Qi dissolving stasis produce, mutually restricts, mutually promotes, to triglycerides, high-density lipoprotein, low close
Degree lipoprotein, immune function have certain therapeutic effect, and certain linear relationship is presented.But cardiac and cerebral blood supply insufficiency is but presented
Be non-linear relation, but in certain proportion, relative efficacy is more preferable.
But during Clinical practice, there is obvious " excessive internal heat " symptom in some patientss, through theory of traditional Chinese medical science discrimination,
The long-term deficiency of vital energy and blood of Patients with Cardiovascular/Cerebrovascular Diseases, can produce fire excess from yin deficiency symptom, along with four taste Chinese medicine of the present composition
Partial temperature, causes correction to stay heresy.
Pueraria lobata, enters spleen, stomach, and expelling pathogenic factors from muscles and skin is brought down a fever, and promoting eruption, promotes the production of body fluid to quench thirst, Shengyang Zhixie.Generate heat for exterior syndrome, stiff nape and back,
Measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea.
Emblic, returns stomach, the spleen channel, sweet in flavor, sour, puckery.With functions such as clearing heat and cooling blood, food digesting stomach fortifying, cough-relievings of promoting the production of body fluid.It is main
Blood-head blood stasis is controlled, indigestion, abdominal distension, coughs, laryngalgia, the disease such as dry.
Radix polygonati officinalis, distributed in lung channel, stomach, tool yin-nourishing, moisturize, heat-clearing, promote the production of body fluid, cough-relieving and other effects.It is dry to cure mainly consumption of YIN caused by febrile disease, abnormal heat
The diseases such as cough.
Pueraria lobata, radix polygonati officinalis, emblic are taken as adjutant, tonifying spleen and stomach, nourishes the gas of the day after tomorrow, aids in the work(of monarch drug in a prescription radix astragali tonifying Qi
Effect；And the effect of taking pueraria lobata, radix polygonati officinalis, emblic clearing heat and nourishing yin, avoid correction from staying heresy, have the function that the eliminating evil that makes corrections.
As a result, the adjutant of prescription of the present invention, reduces the side effect of monarch drug in a prescription ministerial drug；For monarch drug in a prescription ministerial drug primary efficacy simultaneously
Do not cut down, play the role of on the contrary complementary, enhance curative effect.
Seven taste of the above, plays the effect of gas leads to, blood leads to, the heart leads to, brain is logical altogether, and has obvious mitigation to numbness pain, reaches
The effect of heresy is not stayed in correction, available for cardiovascular and cerebrovascular disease secondary prevention.
The content of the invention
The present invention be to provide for a kind of liter be immunized, reducing blood lipid, the Chinese medicine composition and preparation method thereof for protecting heart and brain,
The Chinese medicine composition forms a kind of new rules for the treatment of-" four-way is theoretical ", and instructs prescription by the rules for the treatment of, and prescription is simple, for the heart
The main symptom and common complication of cranial vascular disease Disease are set about, and dissolving stasis is without staying heresy, safe, wide application of the crowd, tool
There is Patients with Cardiovascular/Cerebrovascular Diseases to may be selected, be adapted to cardiovascular and cerebrovascular disease level-one and secondary prevention to be used.
To achieve the object of the present invention, there is provided following technical scheme：
A kind of liter is immunized, reducing blood lipid, protect heart and brain Chinese medicine composition, it is characterised in that the parts by weight of the Chinese medicine composition
Form and be：
250 parts -350 parts of radix astragali, 180 parts -260 parts of Radix Salviae Miltiorrhizae, 150 parts -190 parts of pseudo-ginseng, 100 parts -140 parts of ginkgo leaf, pueraria lobata 100
- 140 parts of part, 60 parts -100 parts of emblic, 60 parts -100 parts of radix polygonati officinalis.
Above-mentioned Chinese medicine composition, it is preferable that the Chinese medicine composition weight composition for 300 parts of radix astragali, 220 parts of Radix Salviae Miltiorrhizae,
170 parts of pseudo-ginseng, 120 parts of ginkgo leaf, 120 parts of pueraria lobata, 80 parts of emblic, 80 parts of radix polygonati officinalis.
Above-mentioned Chinese medicine composition, can add auxiliary material according to a conventional method and preparation is made, and the preparation that can be made into includes tablet, capsule
Agent, powder, pill, granule, paste, oral liquid, sustained release preparation, quick releasing formulation.
The present invention additionally provides a kind of preparation method of the Chinese medicine composition of above-mentioned reducing blood lipid, its operating procedure bag at the same time
Include：
After whole medicinal materials clean removal of impurities, grinding and sieving, the mesh number of sieving is 80-500 mesh, obtains fine powder, encapsulated.
Key point of the present invention is to carry out prescription compatibility using " four-way is theoretical ", selects the Chinese medicine of optimum proportioning, be allowed to
Produce the synergistic effect illustrated in theory of traditional Chinese medical science.
Monarch drug in a prescription radix astragali tonifying Qi, gas energy promoting circulation of blood, carries efficiency and reaches each internal organs, makes each organ normal work of human body, promotes to follow
Loop system cardiac, systemic circulation, the normal rhythm and pace of moving things of muscle recovery and power involved by partial circulating.Monarch drug in a prescription Radix Salviae Miltiorrhizae dissolving stasis, is reduced
Plasma viscosity, makes the turbid reduction of the phlegm on vascular wall and in blood；Axis stream component in vasoactive, reduces the shape of small thrombus
Into.The two is monarch, and collective effect, reaches the organic and functional recovery of cardiovascular system.Pseudo-ginseng, dissipate stasis of blood hemostasis, detumescence are fixed
Bitterly.And with reparation injury of blood vessel, analgesic effect；Ginkgo leaf, for obstruction of collaterals by blood stasis, chest impediment and cardialgia, hemiplegia, deficiency syndrome of the lung cough
Asthma, hyperlipidemia.Due to cardiovascular and cerebrovascular disease long-term existence, can produce anemia damage or run it is not normal may result in it is various not
It is suitable, insomnia, forgetful, irritated, palpitation with fear, stupor etc..Take pseudo-ginseng to dissipate stasis of blood effect and strengthen Radix Salviae Miltiorrhizae dissolving stasis effect, and take analgesic therapy effect,
Numbness pain symptom caused by solving cardiovascular and cerebrovascular disease；Take ginkgo leaf, lipid-loweringing is dispelled turbid, strengthens Radix Salviae Miltiorrhizae dissolving stasis effect, and take analgesic therapy work(
Effect, solves numbness pain symptom caused by cardiovascular and cerebrovascular disease.Radix astragali, Radix Salviae Miltiorrhizae, pseudo-ginseng, ginkgo leaf four traditional Chinese medicine play that gas leads to, blood leads to, the heart altogether
The effect of logical, brain leads to, and have obvious mitigation to numbness pain.The effect of cardiovascular and cerebrovascular disease secondary prevention is reached.Take Pueraria lobota
Root, radix polygonati officinalis, emblic are as adjutant, tonifying spleen and stomach, the effect of nourishing the gas of the day after tomorrow, aid in monarch drug in a prescription radix astragali tonifying Qi；And take pueraria lobata, jade
The effect of bamboo, emblic clearing heat and nourishing yin, avoid correction from staying heresy, have the function that the eliminating evil that makes corrections.
The present composition passes through tonifying Qi dissolving stasis（Strengthen immunity, reduce blood fat）Two approach acts at the same time, to heart and brain
Vascular diseases, such as hyperlipidemia, low density lipoprotein cholesterol（HDL--C）Mass formed by blood stasis, deficiency myocardial blood supply, cerebral insufficiency,
Immunity function decline, other symptoms（Insomnia, weak, anorexia, stomachache, vascular hypertension etc.）Protected etc. there is relatively good treatment
Strong effect, has reached the effect that heresy is not stayed in correction, available for cardiovascular and cerebrovascular disease secondary prevention.
The preparation method of Chinese medicine composition provided by the present invention, it is easy to operate, it is with strong points, according to each taste medicine in prescription
The method that the characteristic of material selects its working process, it is ensured that its active ingredient can extract to greatest extent, preferable to play
Drug effect.
Embodiment
Content of the present invention is described in further detail below in conjunction with specific embodiment.
The clinical test of 1 present composition of embodiment is summarized
From August in 2016 10 days-November 25, this research and development centre selects 78 people to carry out 2.5 months by a definite date on probation.It is existing small
Knot is as follows：
First, case selection
Gender：Male 36, women 42.
Age：35--45 Sui 19,46--56 Sui 27,57-67 years old 32.
Occupation：Retired doctor 12（Containing more than associate chief physician 9）, retired nurse practitioner 3（Containing nurse-in-charge 2）
On-job doctor 2（Attending doctor）, retired professor 8（Containing senior teacher 3）, 15 people of retired cadre（Containing vice department with
Upper 9 people）, 11 people of on-the-job personnel, other 27 people of the retired.
2nd, illness selects
Hyperlipidemia（Medical history more than 5 years, continuous treatment more than 3 years, blood fat is substantially consistently higher than normal）
Low density lipoprotein cholesterol（HDL--C）Mass formed by blood stasis（Medical history more than 6 years, continuously treats more than 4 years index deviants）
Deficiency myocardial blood supply（There are the symptoms such as uncomfortable in chest, shortness of breath, angina pectoris, arrhythmia cordis）
Cerebral insufficiency（It is headache, dizziness, alliteration, tinnitus, numbness, heavy, absent minded, failure of memory, slow in reacting
Deng）
Immunity function declines（Easy catching a cold, fever, respiratory tract infection, have a delicate constitution）
Other symptoms（Insomnia, weak, anorexia, stomachache, vascular hypertension etc.）
3rd, observing time
Hyperlipidemia, low-density lipoprotein mass formed by blood stasis, hypercholesterolemia are 1-1.5 months（It is invalid to be extended down to 2.5 months）
Cardiac and cerebral blood supply insufficiency is 1 month
Immunocyte decline is 2 months
Other symptoms are 1 month
4th, primary part observation index
Triglycerides（TG）
Low-density lipoprotein（HDL—C）
T-CHOL（CHOL）
5th, result is observed
1st, triglycerides（TG）
Normal reference value is：0.4—1.8mmol /L.0.8-2.5mmol/L totally 62 people before this observation.
After 1 month：0.6-1.8mmol/L, 15 people, 0.5-1.5mmol/L, 28 people, 0.5-0.8mmol/L 8
People, without changing 11 people.Effective percentage 82.26%.
After 1.5 months：0.5-1.5mmol/L, 41 people, 0.5-0.8mmol/L, 12 people, without changing 9 people.It is efficient
85.48%。
3rd, after 2.5 months：0.5-0.7mmol/L, 44 people, 0.5-0.6mmol/L, 11 people, 0.4mmol/L, 7
People, effective percentage 88.7%.
To sum up counted, the total effective rate that final observation reduces TG is 85.48%.
, low density lipoprotein cholesterol（HDL--C）
Normal reference value is：0--3.1mmol /L.Elevated totally 55 people of HDL-C before this observation.Wherein：3.2—
37 people of 3.8mmol/L, 3.6-4.2mmol/L, 11 people, 9 people of 4.4mmol/more than L.
After 1.5 months：3.2-3.6mmol/L, 28 people, 3.4-3.6mmol/L, 10 people, 3.5-3.8mmol/L 8
People, 6 people of 3.9-4.2 mmol/L, without changing 9 people.Efficient 81.82%.
After 2.5 months：3.1-3.4mmol/L, 31 people, 3.2-3.6mmol/L, 10 people, 3.3-3.5mmol/L, 7 people,
Without changing 7 people.Efficient 85.45%.
To sum up counted, the total effective rate that final observation reduces HDL-C is 83.64%.
, high T-CHOL mass formed by blood stasis（CHOL）Normal reference value is：0—5.2mmol /L.CHOL is in 5.3- before this observation
78 people of 6.7mmol/L.
After 1 month：5.0-5.6mmol/L, 39 people, 3.2-5.2mmol/L, 17 people, 2.1-4.2mmol/L 5
People, 5 people of 0.5-0.2 mmol/L, without changing 12 people.Efficient 84.62%.
After 1.5 months：4.8-5.3mmol/L, 38 people, 16 people of 3.1-5.1mmol/L, 6 people of 2.2-3.6mmol/L,
7 people of 0.5-0.2 mmol/L, without changing 11 people.Efficient 85.9%.
To sum up counted, the total effective rate that final observation reduces CHOL is 85.26%.
, deficiency myocardial blood supply：There is myocardial ischemia performance before this observation（Uncomfortable in chest, shortness of breath, angina pectoris, arrhythmia cordis etc.）Person
38.Wherein：The electrocardiogram S-T segment person of moving down 15, T ripples are low 6 flat, and T ripples are inverted 1.Tachycardia 12, bradycardia 5
Example, Premature Ventricular Beats 4.
Take in 1 month：Uncomfortable in chest, shortness of breath mitigation 15 in 3-7 days is taken, obvious mitigation 20 in 21 days, has by unchanged 2
Efficiency 92%..Intermittent angina pectoris 11, after taking 28 days, is changed into sporadic angina pectoris 7, remaining 3 have no generation, the heart
Angina remission rate 91%.7-14 days hearts rate of tachycardia it is per minute reduce 12-15 time 6,28 days reduction by 20 times 5.1 without change
Change.Except 5 electrocardiogram S-T segment persons of moving down are changed into normal, remaining is unchanged.
, cerebral insufficiency：There are the symptoms such as headache, dizziness, alliteration totally 22.Take in 1 month：Headache, dizziness are obvious
Mitigate 16.Alliteration mitigates 4.Remaining is unchanged.
, immune dysfunction：35 people of respiratory tract infection person is often suffered from, while merges lower respiratory tract infection, fever person 8
People.Almost every month is all susceptible.Take composition capsule 2 months, flu person only 6 people.The infected without.Effective percentage 82.86%.
, other symptoms：Have a sleepless night, is 15 weak, taking improves 12 for 3-7 days, improves 14 within 1 month, 1 without improvement.Stomach
Bitterly, gasteremphraxis, apocleisis 7, improves 5 in 1 month.Blood pressure 130-150/90mmHg29,140-160/90-100mmHg11
Example.Take 1 month, 32 people systolic blood pressure harmonic(-)mean 5-10 mmHg, diastolic pressure averagely reduces by 5 mmHg, and 8 unchanged.
6th, summarize
1st, by thinking, composition capsule is to reducing triglycerides（TG）, and reduce low density lipoprotein cholesterol
（HDL--C）, high T-CHOL mass formed by blood stasis（CHOL）Good results.Total effective rate is respectively 85.48%, 83.64%, 85.26%.Take
Time is longer, and effect shows more obvious, and rule is：2.5 months >=1.5 months >=1 month.
2nd, composition capsule is to improving caused by deficiency myocardial blood supply such as：Uncomfortable in chest, shortness of breath, angina pectoris, tachycardia etc.
Effect is preferable, to more than 92% often appearance is uncomfortable in chest, shortness of breath manifest symptom person, ideal effect can be received.Angina
Rate is up to 91%.But reverse ischemic electrocardiographic effect general.The reason is that Time of Administration deficiency causes.
3rd, composition capsule is to the symptom such as headache, dizziness, alliteration caused by improving cerebral insufficiency, also relatively good effect
Fruit.Effective percentage about 72.7%.
4th, composition capsule is preferable with weak effect to improving sleep, takes effect within 1 week and accounts for 80%, 1 month effective percentage 93%.
In addition, it to mitigate stomachache, apocleisis, reduce blood pressure it is all effective.
5th, composition capsule is effective to improving immunity.Suppress flu and cause lower respiratory tract infection efficient
82.86%。
6th, the effect of composition capsule without direct intervention and is influenced by factors such as analysis, age, gender, occupations.
The preparation of the capsule of 2 Chinese medicine composition of embodiment
Take 250 kg of radix astragali, 180 kg of Radix Salviae Miltiorrhizae, 150 kg of pseudo-ginseng, 100 kg of ginkgo leaf, 100 kg of pueraria lobata, 60 kg of emblic, jade
60 kg of bamboo.
After whole medicinal materials clean removal of impurities, grinding and sieving, the mesh number of sieving is 80-500 mesh, obtains fine powder, encapsulated.
The preparation of the tablet of 3 Chinese medicine composition of embodiment
Take 350 kg of radix astragali, 260 kg of Radix Salviae Miltiorrhizae, 190 kg of pseudo-ginseng, 140 kg of ginkgo leaf, 140 kg of pueraria lobata, 100 kg of emblic,
100 kg of radix polygonati officinalis.
By broken 500 mesh sieves excessively afterwards of superfine notoginseng powder, it is spare to obtain pseudo-ginseng fine powder.
After radix astragali, Radix Salviae Miltiorrhizae, ginkgo leaf, pueraria lobata, emblic, radix polygonati officinalis are cleaned removal of impurities, respectively plus 50% ethanol water soaks
When decoction extraction 3 is small afterwards, after extracting solution filtering, it is concentrated under reduced pressure, obtains Astragalus Root P.E medicinal extract, Salvia root P.E medicinal extract, ginkgo leaf
Extract medicinal extract, kudzu root extract medicinal extract, emblic extract medicinal extract, Rhizoma Polygonati Odorati extract medicinal extract.
By above-mentioned Astragalus Root P.E medicinal extract, Salvia root P.E medicinal extract, ginkgo biloba p.e medicinal extract, kudzu root extract medicinal extract,
Emblic extract medicinal extract, Rhizoma Polygonati Odorati extract medicinal extract are dried respectively, ultramicro grinding, cross 500 mesh sieves, it is thin to obtain Astragalus Root P.E
Powder, Salvia root P.E fine powder, ginkgo biloba p.e fine powder, kudzu root extract fine powder, emblic extract fine powder, Rhizoma Polygonati Odorati extract
Fine powder is spare.
Take extract fine powder to be uniformly mixed, add auxiliary material according to a conventional method and preparation piece agent is made.
The preparation of the granule of 4 Chinese medicine composition of embodiment
Take 300 kg of radix astragali, 230 kg of Radix Salviae Miltiorrhizae, 180 kg of pseudo-ginseng, 110 kg of ginkgo leaf, 110 kg of pueraria lobata, 90 kg of emblic, jade
70 kg of bamboo.
200 mesh sieves are crossed after pseudo-ginseng is crushed, it is spare to obtain pseudo-ginseng fine powder.
After radix scutellariae, Radix Salviae Miltiorrhizae, ginkgo leaf, pueraria lobata, emblic, radix polygonati officinalis are cleaned removal of impurities, decoct respectively plus after the immersion of 70% ethanol
Extract 2 it is small when, extracting solution filtering after, be concentrated under reduced pressure, obtain Astragalus Root P.E medicinal extract, Salvia root P.E medicinal extract, ginkgo biloba p.e
Medicinal extract, kudzu root extract medicinal extract, emblic extract medicinal extract, Rhizoma Polygonati Odorati extract medicinal extract.
By above-mentioned Astragalus Root P.E medicinal extract, Salvia root P.E medicinal extract, ginkgo biloba p.e medicinal extract, kudzu root extract medicinal extract,
Emblic extract medicinal extract, Rhizoma Polygonati Odorati extract medicinal extract are dried respectively, crush, cross 200 mesh sieves, obtain Salvia root P.E fine powder,
Ginkgo biloba p.e fine powder, kudzu root extract fine powder, emblic extract fine powder, Rhizoma Polygonati Odorati extract fine powder are spare.
Each extract fine powder is taken to be uniformly mixed, addition auxiliary material, which is made, according to a conventional method is prepared into granule.
Above example has carried out detailed description to the present invention, but on the basis of the present invention, can be with being done to it
Modification improves, this is obvious for a person skilled in the art.Therefore, the modification made on the basis of without departing from the present invention
Or improve, belong to the scope of protection of present invention.
In conclusion present invention offer rises immune, reducing blood lipid, the Chinese medicine composition tool of protection heart and brain is significantly improved and exempts from
The effect of epidemic disease power, reducing blood lipid, and on this basis, there is treatment and protective effect to cardiovascular and cerebrovascular, it is safe, suitable for big
Most Patients with Cardiovascular/Cerebrovascular Diseases are used as level-one, two level protection.
Claims (7)
1. a kind of liter is immunized, reducing blood lipid, protect heart and brain Chinese medicine composition, it is characterised in that the weight of the Chinese medicine composition
Part forms：
250 parts -350 parts of radix astragali, 180 parts -260 parts of Radix Salviae Miltiorrhizae, 150 parts -190 parts of pseudo-ginseng, 100 parts -140 parts of ginkgo leaf, pueraria lobata 100
- 140 parts of part, 60 parts -100 parts of emblic, 60 parts -100 parts of radix polygonati officinalis.
2. a kind of liter as claimed in claim 1 is immunized, reducing blood lipid, the Chinese medicine composition for protecting heart and brain, it is characterised in that it is described
The parts by weight of Chinese medicine composition form：
270 parts -320 parts of radix astragali, 200 parts -230 parts of Radix Salviae Miltiorrhizae, 160 parts -180 parts of pseudo-ginseng, 115 parts -130 parts of ginkgo leaf, pueraria lobata 110
- 130 parts of part, 75 parts -90 parts of emblic, 70 parts -85 parts of radix polygonati officinalis.
3. a kind of liter as claimed in claim 1 is immunized, reducing blood lipid, the Chinese medicine composition for protecting heart and brain, it is characterised in that it is described
The parts by weight of Chinese medicine composition form：
300 parts of radix astragali, 220 parts of Radix Salviae Miltiorrhizae, 170 parts of pseudo-ginseng, 120 parts of ginkgo leaf, 120 parts of pueraria lobata, 80 parts of emblic, 80 parts of radix polygonati officinalis.
4. a kind of liter as described in claim 1-3 is any is immunized, reducing blood lipid, the Chinese medicine composition for protecting heart and brain, its feature exists
Crushing, water extraction, alcohol extracting, the extraction of water alcohol mix reagent can be used in its active ingredient.
5. a kind of liter as claimed in claim 4 is immunized, reducing blood lipid, the Chinese medicine composition for protecting heart and brain, it is characterised in that it is made
Agent can be got by the following method：After whole medicinal materials clean removal of impurities, grinding and sieving, the mesh number of sieving is 80-500 mesh, is obtained
Fine powder, it is encapsulated.
6. a kind of liter as claimed in claim 4 is immunized, reducing blood lipid, the Chinese medicine composition for protecting heart and brain, it is characterised in that it is lived
Property component preparation can be got by the following method：After whole medicinal materials clean removal of impurities, difference or mixing and water adding or various concentrations
Ethanol water immersion after decoct extraction, the addition of solvent is 8-10 times, the time for decocting extraction be 1 hour to 3 it is small when,
After extracting solution filtering, it is concentrated under reduced pressure, up to active ingredient.
7. a kind of liter as claimed in claim 6 is immunized, reducing blood lipid, the Chinese medicine composition for protecting heart and brain, it is characterised in that it is lived
Property component can be prepared with acceptable carrier combination in pharmacy.
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| CN116832116A (en) * | 2023-07-04 | 2023-10-03 | 河北御芝林生物科技有限公司 | Application of composition in preparation of product for improving or preventing heart injury caused by surgery |
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| CN103829238A (en) * | 2014-02-17 | 2014-06-04 | 大连圣弘医药有限公司 | Blood lipid lowering health food and preparation method thereof |
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2018
- 2018-01-18 CN CN201810048280.1A patent/CN108014267A/en not_active Withdrawn
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| CN103829238A (en) * | 2014-02-17 | 2014-06-04 | 大连圣弘医药有限公司 | Blood lipid lowering health food and preparation method thereof |
| CN103948791A (en) * | 2014-03-28 | 2014-07-30 | 河北御芝林药业有限公司 | Traditional Chinese medicinal composition for reducing blood fat, and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116832116A (en) * | 2023-07-04 | 2023-10-03 | 河北御芝林生物科技有限公司 | Application of composition in preparation of product for improving or preventing heart injury caused by surgery |
| CN116832116B (en) * | 2023-07-04 | 2024-03-12 | 河北御芝林生物科技有限公司 | Application of composition in preparation of product for improving or preventing heart injury caused by surgery |
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