CN108014175A - A kind of plant composition for being used to alleviate Rhinitis Symptoms - Google Patents

A kind of plant composition for being used to alleviate Rhinitis Symptoms Download PDF

Info

Publication number
CN108014175A
CN108014175A CN201711240322.3A CN201711240322A CN108014175A CN 108014175 A CN108014175 A CN 108014175A CN 201711240322 A CN201711240322 A CN 201711240322A CN 108014175 A CN108014175 A CN 108014175A
Authority
CN
China
Prior art keywords
extract
parts
extraction
small
peppermint
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711240322.3A
Other languages
Chinese (zh)
Inventor
赵传海
马铭鸿
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chen Bingkun (tianjin) Biotechnology Co Ltd
Original Assignee
Chen Bingkun (tianjin) Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chen Bingkun (tianjin) Biotechnology Co Ltd filed Critical Chen Bingkun (tianjin) Biotechnology Co Ltd
Priority to CN201711240322.3A priority Critical patent/CN108014175A/en
Publication of CN108014175A publication Critical patent/CN108014175A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides a kind of plant composition for being used to alleviate Rhinitis Symptoms, it is made of the component of following volume parts:46 parts of 20 30 parts of cajeputtree extract, 15 25 parts of Himalaya Cedarwood extract, 15 25 parts of peppermint extract, 8 12 parts of balsam fir extract, 8 12 parts of Rosmarinus officinalis extract, 8 12 parts of cypress extract and Luo Wensha leaf extracts.The cajeputtree extract extracted by ad hoc fashion, Himalaya Cedarwood extract, peppermint extract, balsam fir extract, Rosmarinus officinalis extract, cypress extract and Luo Wensha leaf extracts are combined by the present invention, pass through mutual cooperation, the product prepared can be relieved the symptoms such as paroxysmal sneeze caused by allergic rhinitis, clear water sample nasal mucus, nasal obstruction and rhiocnesmus, positive effect, it is easy to use, Small side effects, can be with long-time service.

Description

A kind of plant composition for being used to alleviate Rhinitis Symptoms
Technical field
The invention belongs to medicines and health protection technical field, more particularly, to a kind of plant society for being used to alleviate Rhinitis Symptoms Thing.
Background technology
Allergic rhinitis, that is, allergic rhinitis, after referring to atopic individuals contact allergen, is mainly situated between by immunoglobulin Medium (mainly histamine) release led, and have the schneiderian membrance of the participations such as panimmunity competent cell and cell factor non-infectious Inflammatory disease.Its necessary condition occurred has 3:Specific antigen is the material for causing organism immune response;Atopic individuals I.e. so-called individual difference, allergic constitution;Specific antigen answers both type individuals to meet with spy.
Allergic rhinitis are a global health problems, can cause many diseases and disability, and cannot control More, can only relief of symptoms.
Primary treatments have following several at present:Oral or nose spray antihistamine, is only applicable to mild intermittent and light Spend continuation allergic rhinitis;Oral or nose spray Adrenal Glucocorticoid, effect is preferable, but long-time service drug effect can gradually drop Low, side effect is larger, is only suitable for short;Immunotherapy needs the continued treatment of at least more than 2 years, and method is still immature, Curative effect and side effect are still uncertain;External application nasal douche, effect unobvious and inconvenient to use.
The content of the invention
In view of this, the present invention is directed to propose a kind of plant composition for being used to alleviate Rhinitis Symptoms, effectively treats rhinitis, Significant effect.
To reach above-mentioned purpose, the technical proposal of the invention is realized in this way:
A kind of plant composition for being used to alleviate Rhinitis Symptoms, is made of the component of following volume parts:
20-30 parts of cajeputtree extract, 15-25 parts of Himalaya Cedarwood extract, 15-25 parts of peppermint extract, 4-6 parts of 8-12 parts of balsam fir extract, 8-12 parts of Rosmarinus officinalis extract, 8-12 parts of cypress extract and Luo Wensha leaf extracts.
Further, the component by following volume parts forms:
23-28 parts of cajeputtree extract, 16-22 parts of Himalaya Cedarwood extract, 17-23 parts of peppermint extract, 4-6 parts of 8-11 parts of balsam fir extract, 8-10 parts of Rosmarinus officinalis extract, 10-12 parts of cypress extract and Luo Wensha leaf extracts.
Further, the component by following volume parts forms:
25 parts of cajeputtree extract, 20 parts of Himalaya Cedarwood extract, 20 parts of peppermint extract, balsam fir extraction 5 parts of 10 parts of thing, 10 parts of Rosmarinus officinalis extract, 10 parts of cypress extract and Luo Wensha leaf extracts.
Further, the extraction process of the cajeputtree extract is as follows:
Using supercritical CO2Abstraction technique, takes Cajeputtree Leaf, using temperature as 60 DEG C drying 0.5-1.5 it is small when, crushed 40 Mesh sieve, adds in extraction kettle, and sets CO2Circular flow is 25kg/h, and extracting pressure 30-35Mpa, temperature is 42-48 DEG C, When extraction time is 2-3 small, entrainer is done using ethanol, its mass concentration is 60%, after extraction, isolated cajeputtree Extract.
Further, the extraction process of the Himalaya Cedarwood extract is as follows:
Using steam distillation, Himalaya cedar leaf is taken, when using oven for drying 2 small at 65-70 DEG C, crushes, crosses 30 Mesh sieve, is fitted into distillation still, adds 10 times of water, when immersion 2-3 is small after be heated to seething with excitement, keep slightly boiling distillation 1 small under normal pressure When, condensate liquid is collected, stops heating;After being cooled to room temperature, water-oil separating is carried out by oil water separator, obtains Himalaya snow Loose extract.
Further, the extraction process of the peppermint extract is as follows:
Using steam distillation, peppermint branch and leaf are dried in the shade, adds in agitating ball mill, is 300- in rotating speed Mechanical activation 5-10min under 800r/min, obtains peppermint powder;Above-mentioned peppermint powder is added into alembic, adds fibre The plain enzyme of dimension and water, the weight of cellulase is peppermint powder weight 0.5-0.8%, is pressurizeed with slabstone so that water just steeped peppermint Powder, when immersion 2-3 is small at normal temperatures, obtains extracting solution;Vapor is passed through from the bottom of alembic to heat extracting solution, When extraction 1.5-2 is small after extracting solution boiling, mixed vapour is obtained;Mixed vapour is condensed by condenser, is obtained after condensation Oil water mixture;Water-oil separating is carried out by oil water separator, obtains peppermint crude oil and water;Extracted again by extractor, After layering, it is peppermint essential oil to separate upper strata.
Further, the extraction process of the balsam fir extract is as follows:
Using steam distillation, the bark, branch, leaf of balsam fir are broken into the little particle of 2-3cm, dried in the shade, crushed, mistake 20 mesh sieves, add 8-12 times of water, and when Dipping 2-3 is small, distillation pot bottom is passed through vapor heating, and mixed vapour condensation, obtains Oil water mixture;Separated through separator, obtain crude extract;Filtered and removed water by anhydrous sodium sulfate, obtain balsam fir extract.
Further, the extraction process of the Rosmarinus officinalis extract is as follows:
Using CO2Supercritical extraction process, takes the cauline leaf of rosemary, and vacuum freeze-drying, crushes, and crosses 20 mesh sieves, adjusts CO2Follow Circulation is 20-25kg/h, and extraction temperature is 40 DEG C, extracting pressure 20MPa, when extraction 1.5-2.5 is small, is pressed from both sides using ethanol Band agent, its mass concentration are 60%, separating and extracting product and CO2, empty CO2, obtain Rosmarinus officinalis extract.
Further, the extraction process of the cypress extract is as follows:
Using supercritical CO2Abstraction technique, takes cypress leaf and fruit ball, and fruit ball is crushed, and confuses leaf using temperature as 60 DEG C of bakings When dry 1.5-2.5 is small, 20 mesh sieves are crushed, are added in extraction kettle, and CO is set2Circular flow is 20kg/h, and extracting pressure is 10-17Mpa, temperature is 40 DEG C, when extraction time is 1.5-2.5 small, after extraction, and isolated cypress extract.
Further, the extraction process of the Luo Wensha leaf extracts is as follows:
Using steam distillation, take the leaf of Luo Wenshaye, using temperature as 60 DEG C of drying 0.5-1.5 it is small when, crushed 20 Mesh sieve, adds among reaction kettle, while adds 25% sodium chloride, connects distilling apparatus, carries out steam distillation, keeps slightly boiling When state reflux 3 is small, continue to heat, collect condensate liquid, obtain oil water mixture;Water-oil separating is carried out by oil water separator, Obtain Luo Wensha leaf extracts.
Cajeputtree extract, peppermint extract, balsam fir extract, Rosmarinus officinalis extract, cypress extract, Luo Wen Contained firpene, laurene, limonene can speed up blood circulation in Sha's leaf extract, accelerate the absorption of active material.
Terpinolene contained in contained terpinene and cypress extract plays the role of anti-inflammatory in Luo Wensha leaf extracts.
It is contained in contained carypohyllene, Himalaya Cedarwood extract in Luo Wensha leaf extracts and peppermint extract Cedrene play the role of antihistamine, suppress allergy, reduce mucosal tissue hyperemia and oedema, reduce nasal secretion.
Contained menthones in peppermint extract, contained atlantom is reduced in Himalaya Cedarwood extract The effect of nasal membrane secretion.
Contained eucalyptus oil in cajeputtree extract, Rosmarinus officinalis extract, peppermint extract, Luo Wensha leaf extracts Alcohol has bactericidal antiphlogistic, promotes blood circulation, and reduces the effect of nasal membrane secretion.
Relative to the prior art, the plant composition of the present invention for being used to alleviate Rhinitis Symptoms has the advantage that:
The plant composition of the present invention for being used to alleviate Rhinitis Symptoms, the cajeputtree that will be extracted by ad hoc fashion Extract, Himalaya Cedarwood extract, peppermint extract, balsam fir extract, Rosmarinus officinalis extract, cypress extract It is combined with Luo Wensha leaf extracts, by mutual cooperation, the product prepared can be relieved allergia nose The symptom such as paroxysmal sneeze, clear water sample nasal mucus, nasal obstruction and rhiocnesmus caused by inflammation, positive effect is easy to use, and Small side effects can With long-time service.
Embodiment
In addition to being defined, technical term used has universal with those skilled in the art of the invention in following embodiments The identical meanings of understanding.Test reagent used, is routine biochemistry reagent unless otherwise specified in following embodiments;It is described Experimental method, is conventional method unless otherwise specified.
With reference to embodiment, the present invention will be described in detail.
The extraction of cajeputtree extract:
Using supercritical CO2Abstraction technique, takes Cajeputtree Leaf, using temperature as 60 DEG C drying 1 it is small when, crushed 40 mesh sieves, Add in extraction kettle, and CO is set2Circular flow is 25kg/h, and extracting pressure 33Mpa, temperature is 47 DEG C, and extraction time is 3 Hour, entrainer is done using ethanol, its mass concentration is 60%, after extraction, isolated cajeputtree extract.
The extraction of Himalaya Cedarwood extract:
Using steam distillation, Himalaya cedar leaf is taken, when using oven for drying 2 small at 70 DEG C, crushes, crosses 30 mesh Sieve, is fitted into distillation still, add 10 times of water, immersion 2 it is small when after be heated to seething with excitement, under normal pressure keep slightly boiling distillation 1 it is small when, receipts Collect condensate liquid, stop heating;After being cooled to room temperature, water-oil separating is carried out by oil water separator, Himalaya deodar is obtained and carries Take thing.
The extraction of peppermint extract:
Using steam distillation, peppermint branch and leaf are dried in the shade, adds in agitating ball mill, is 500r/ in rotating speed Mechanical activation 10min under min, obtains peppermint powder;By above-mentioned peppermint powder add alembic, add cellulase and Water, the weight of cellulase is peppermint powder weight 0.6%, is pressurizeed with slabstone so that water just steeps excessively thin charged powders, in room temperature It is lower immersion 3 it is small when, obtain extracting solution;Vapor is passed through from the bottom of alembic to heat extracting solution, after extracting solution boiling Extract 1.5 it is small when, obtain mixed vapour;Mixed vapour is condensed by condenser, and oil water mixture is obtained after condensation;By Oil water separator carries out water-oil separating, obtains peppermint crude oil and water;Extracted again by extractor, after layering, separate upper strata As peppermint essential oil.
The extraction of balsam fir extract:
Using steam distillation, the bark, branch, leaf of balsam fir are broken into the little particle of 2-3cm, dried in the shade, crushed, mistake 20 mesh sieves, add 10 times of water, and when Dipping 2 is small, distillation pot bottom is passed through vapor heating, and mixed vapour condensation, obtains grease Mixture;Separated through separator, obtain crude extract;Filtered and removed water by anhydrous sodium sulfate, obtain balsam fir extract.
The extraction of Rosmarinus officinalis extract:
Using CO2Supercritical extraction process, takes the cauline leaf of rosemary, and vacuum freeze-drying, crushes, and crosses 20 mesh sieves, adjusts CO2Follow Circulation is 25kg/h, and extraction temperature is 40 DEG C, extracting pressure 20MPa, when extraction 2 is small, does entrainer using ethanol, its matter It is 60% to measure concentration, separating and extracting product and CO2, empty CO2, obtain Rosmarinus officinalis extract.
The extraction of cypress extract:
Using supercritical CO2Abstraction technique, takes cypress leaf and fruit ball, and fruit ball is crushed, and confuses leaf using temperature as 60 DEG C of bakings It is dry 2 it is small when, crushed 20 mesh sieves, add in extraction kettle, and CO is set2Circular flow is 20kg/h, extracting pressure 15Mpa, Temperature is 40 DEG C, when extraction time is 2 small, after extraction, and isolated cypress extract.
The extraction of Luo Wensha leaf extracts:
Using steam distillation, take the leaf of Luo Wenshaye, using temperature as 60 DEG C of drying 1 it is small when, crushed 20 mesh sieves, add Enter among reaction kettle, while add 25% sodium chloride, connect distilling apparatus, carry out steam distillation, keep slight boiling condition to return Flow 3 it is small when, continue to heat, collect condensate liquid, obtain oil water mixture;Water-oil separating is carried out by oil water separator, obtains sieve Literary Sha's leaf extract.
By the raw material of following volume parts, uniformly mixing is i.e. available:25 parts of cajeputtree extract, Himalaya deodar carry Take 20 parts of thing, 20 parts of peppermint extract, 10 parts of balsam fir extract, 10 parts of Rosmarinus officinalis extract, 10 parts of cypress extract With 5 parts of Luo Wensha leaf extracts.
Application method:
Appropriate product is taken to be applied in people, Jingming acupoint is to wing of nose both sides between fragrant cave, are touched 15-20 times, three times a day, One week as a treatment course.
Clinical test statistics of the present invention is as follows:
Case Recovery from illness Significant curative effect Effectively It is invalid It is efficient
100 84 11 1 4 96.0%
Wherein above curative effect determinate standard is:Treatment, which is not recurred in two course for the treatment of latter years, to be confirmed as fully recovering;Two treatments for the treatment of
Recurred in Cheng Houyi to be effective;State of an illness mitigation is effective after treating two courses for the treatment of;Without bright after two courses for the treatment of of treatment It is aobvious be improved as it is invalid.
By the patient to 100 allergic rhinitis diseases by product of the present invention treat two courses for the treatment of after, share 4 people without Effect, total effective rate reach 96.0%.
Use the effect of wherein more typical case further illustrates the present invention after the present invention.
Case one:Ma, female, people from Liaoning 32 years old, obtain allergic rhinitis 5 years, there is family's allergies, controlled for many years through hospital It is invalid to treat, and aggravates year by year, when having an attack of one's old illness sneezing and flow clear tears, by the present invention treat two courses for the treatment of after rhinitis healing, in 1 year Do not recur.
Case two:Certain is shut out, female, people from Chongqing, 24 years old, obtains allergic rhinitis 3 years after going to school to the north, no family's allergies, Severe nasal blockage when having an attack of one's old illness, by rhinitis healing after the present invention two courses for the treatment of of treatment, does not recur in 1 year.
Case three:Lee, female, people from Sichuan, 22 years old, obtains allergic rhinitis 2 years after going to school to the north, no family's allergies, Have a stuffy nose when having an attack of one's old illness, by rhinitis healing after the present invention two courses for the treatment of of treatment, recurred after 1 year, and use one treatment of product of the present invention Rehabilitation after journey.
Case four:Yin certain, man, people from Shandong, 46 years old, obtains allergic rhinitis 8 years, and no family's allergies, various methods are for many years Treatment is invalid, sneezes non-stop when having an attack of one's old illness and flow clear tears, seriously affects quality of life, and nose after two courses for the treatment of is treated by the present invention Scorching rehabilitation, does not recur in 1 year.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention With within principle, any modification, equivalent replacement, improvement and so on, should all be included in the protection scope of the present invention god.

Claims (10)

  1. A kind of 1. plant composition for being used to alleviate Rhinitis Symptoms, it is characterised in that:It is made of the component of following volume parts:
    20-30 parts of cajeputtree extract, 15-25 parts of Himalaya Cedarwood extract, 15-25 parts of peppermint extract, glue are cold 4-6 parts of 8-12 parts of China fir extract, 8-12 parts of Rosmarinus officinalis extract, 8-12 parts of cypress extract and Luo Wensha leaf extracts.
  2. 2. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:By following parts by volume Several component compositions:
    23-28 parts of cajeputtree extract, 16-22 parts of Himalaya Cedarwood extract, 17-23 parts of peppermint extract, glue are cold 4-6 parts of 8-11 parts of China fir extract, 8-10 parts of Rosmarinus officinalis extract, 10-12 parts of cypress extract and Luo Wensha leaf extracts.
  3. 3. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:By following parts by volume Several component compositions:
    25 parts of cajeputtree extract, 20 parts of Himalaya Cedarwood extract, 20 parts of peppermint extract, balsam fir extract 10 Part, 10 parts of Rosmarinus officinalis extract, 10 parts of cypress extract and 5 parts of Luo Wensha leaf extracts.
  4. 4. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Cajeputtree extract Extraction process it is as follows:
    Using supercritical CO2Abstraction technique, takes Cajeputtree Leaf, using temperature as 60 DEG C drying 0.5-1.5 it is small when, crushed 40 mesh sieves, Add in extraction kettle, and CO is set2Circular flow is 25kg/h, and extracting pressure 30-35Mpa, temperature is 42-48 DEG C, extraction When time is 2-3 small, entrainer is done using ethanol, its mass concentration is 60%, after extraction, isolated cajeputtree extraction Thing.
  5. 5. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Himalaya deodar The extraction process of extract is as follows:
    Using steam distillation, Himalaya cedar leaf is taken, when using oven for drying 2 small at 65-70 DEG C, crushes, crosses 30 mesh sieves, Be fitted into distillation still, add 10 times of water, immersion 2-3 it is small when after be heated to seething with excitement, under normal pressure keep slightly boiling distillation 1 it is small when, receive Collect condensate liquid, stop heating;After being cooled to room temperature, water-oil separating is carried out by oil water separator, Himalaya deodar is obtained and carries Take thing.
  6. 6. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Peppermint extracts The extraction process of thing is as follows:
    Using steam distillation, peppermint branch and leaf are dried in the shade, adds in agitating ball mill, is 300-800r/ in rotating speed Mechanical activation 5-10min under min, obtains peppermint powder;Above-mentioned peppermint powder is added into alembic, adds cellulase And water, the weight of cellulase is peppermint powder weight 0.5-0.8%, is pressurizeed with slabstone and causes water just to steep excessively thin charged powders, When immersion 2-3 is small at normal temperatures, extracting solution is obtained;Vapor is passed through from the bottom of alembic to heat extracting solution, is extracted When extraction 1.5-2 is small after liquid boiling, mixed vapour is obtained;Mixed vapour is condensed by condenser, and grease is obtained after condensation Mixture;Water-oil separating is carried out by oil water separator, obtains peppermint crude oil and water;Extracted, be layered by extractor again Afterwards, it is peppermint essential oil to separate upper strata.
  7. 7. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Balsam fir extract Extraction process it is as follows:
    Using steam distillation, the bark, branch, leaf of balsam fir are broken into the little particle of 2-3cm, dried in the shade, crushed, cross 20 mesh Sieve, adds 8-12 times of water, and when Dipping 2-3 is small, distillation pot bottom is passed through vapor heating, and mixed vapour condensation, obtains grease Mixture;Separated through separator, obtain crude extract;Filtered and removed water by anhydrous sodium sulfate, obtain balsam fir extract.
  8. 8. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Rosmarinus officinalis extract Extraction process it is as follows:
    Using CO2Supercritical extraction process, takes the cauline leaf of rosemary, and vacuum freeze-drying, crushes, and crosses 20 mesh sieves, adjusts CO2Recycle stream It is 40 DEG C, extracting pressure 20MPa to measure as 20-25kg/h, extraction temperature, when extraction 1.5-2.5 is small, is carried secretly using ethanol Agent, its mass concentration are 60%, separating and extracting product and CO2, empty CO2, obtain Rosmarinus officinalis extract.
  9. 9. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Cypress extract Extraction process is as follows:
    Using supercritical CO2Abstraction technique, takes cypress leaf and fruit ball, and fruit ball is crushed, and confuses leaf using temperature as 60 DEG C of drying 1.5- 2.5 it is small when, crushed 20 mesh sieves, add in extraction kettle, and CO is set2Circular flow is 20kg/h, extracting pressure 10- 17Mpa, temperature is 40 DEG C, when extraction time is 1.5-2.5 small, after extraction, and isolated cypress extract.
  10. 10. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Luo Wenshaye is carried Take the extraction process of thing as follows:
    Using steam distillation, take the leaf of Luo Wenshaye, using temperature as 60 DEG C of drying 0.5-1.5 it is small when, crushed 20 mesh sieves, Add among reaction kettle, while add 25% sodium chloride, connect distilling apparatus, carry out steam distillation, keep slight boiling condition Flow back 3 it is small when, continue to heat, collect condensate liquid, obtain oil water mixture;Water-oil separating is carried out by oil water separator, is obtained Luo Wensha leaf extracts.
CN201711240322.3A 2017-11-30 2017-11-30 A kind of plant composition for being used to alleviate Rhinitis Symptoms Pending CN108014175A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711240322.3A CN108014175A (en) 2017-11-30 2017-11-30 A kind of plant composition for being used to alleviate Rhinitis Symptoms

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711240322.3A CN108014175A (en) 2017-11-30 2017-11-30 A kind of plant composition for being used to alleviate Rhinitis Symptoms

Publications (1)

Publication Number Publication Date
CN108014175A true CN108014175A (en) 2018-05-11

Family

ID=62077768

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711240322.3A Pending CN108014175A (en) 2017-11-30 2017-11-30 A kind of plant composition for being used to alleviate Rhinitis Symptoms

Country Status (1)

Country Link
CN (1) CN108014175A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109464581A (en) * 2019-01-18 2019-03-15 唐心尧 A kind of composition and application thereof for alleviating Rhinitis Symptoms

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634349A (en) * 2004-11-04 2005-07-06 上海交通大学 Incense fumigating agent for coryza
CN105055788A (en) * 2015-09-21 2015-11-18 马振玲 Pharmaceutical composition for treating anaphylactic rhinitis
CN105106069A (en) * 2015-09-11 2015-12-02 金玛瑙香水(明光)有限公司 Health-care perfume having function of preventing allergic rhinitis
CN106963816A (en) * 2017-04-16 2017-07-21 宁松 A kind of traditional Chinese medicine for outer use for treating rhinitis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634349A (en) * 2004-11-04 2005-07-06 上海交通大学 Incense fumigating agent for coryza
CN105106069A (en) * 2015-09-11 2015-12-02 金玛瑙香水(明光)有限公司 Health-care perfume having function of preventing allergic rhinitis
CN105055788A (en) * 2015-09-21 2015-11-18 马振玲 Pharmaceutical composition for treating anaphylactic rhinitis
CN106963816A (en) * 2017-04-16 2017-07-21 宁松 A kind of traditional Chinese medicine for outer use for treating rhinitis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘莉莉等: "基于过敏性鼻炎大鼠模型优选鼻鼽颗粒提取工艺", 《世界科学技术-中医药现代化》 *
张学梅: "用富含迷迭香酸的紫苏提取物治疗季节性过敏性鼻炎", 《国外医药.植物药分册》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109464581A (en) * 2019-01-18 2019-03-15 唐心尧 A kind of composition and application thereof for alleviating Rhinitis Symptoms

Similar Documents

Publication Publication Date Title
CN101616681B (en) Composition for treating atopic dermatitis comprising extracts of bamboo and scutellaria
CN103750107B (en) Health-care product with blood glucose reducing function
WO2018176647A1 (en) Chinese medicine for treating thiamine deficiency
CN108210867A (en) A kind of palm moxibustion liquid for treating pain and preparation method thereof
CN108014175A (en) A kind of plant composition for being used to alleviate Rhinitis Symptoms
CN109453208A (en) A kind of method that the quick-fried technology of normal pressure sulfur trioxide gas low-grade fever extracts traditional Chinese medicine ingredients
CN104288521A (en) Traditional Chinese medicinal composition for treating diarrhea and preparation method and application thereof
CN108715560A (en) A kind of production fertilizer zymotic fluid and preparation method thereof
CN104001118A (en) Medicament for treating damp-heat spreading type motor neuron diseases and preparation method thereof
CN106511661A (en) Acne removal mask as well as preparation and application
CN104971271A (en) Medicine for treating benign prostatic hyperplasia due to damp-retained heat and preparation method thereof
CN106188083B (en) A method of extracting 1, 8-Cineole volatile oil from folium artemisiae argyi
CN104306832A (en) Chinese herba preparation for treating viral myocarditis and preparing method thereof
CN104013875B (en) A kind of blood pressure lowering black plaster and preparation method thereof
CN110613841B (en) Snailase traditional Chinese medicine ointment for treating psoriasis and preparation method thereof
WO2018176642A1 (en) Chinese medicine for treating skin inflammation
CN110812451B (en) Pain arthralgia pill and preparation method and application thereof
CN1045060C (en) Laxative Chinese medicine capable of lowering level of human free radical
CN106963833B (en) Medicine for treating cold of children and adults and preparation method thereof
Arunachalam et al. Antidiabetic Activity by the In Vitro α-Amylase and α-Glucosidase Inhibitory Action of Indian Ayurvedic Medicinal Plants: Ficus amplissima Smith
CN103784880A (en) Traditional Chinese medicine composition for treating pulmonary emphysema and preparation method of traditional Chinese medicine composition
CN116850203A (en) Use of fucoidan and its composition in treating allergic rhinitis
CN109731093A (en) A kind of Chinese medicine composition and its preparation method and application of raw bone promoting blood circulation and removing obstruction in channels
CN102028920A (en) Application of Tibetan medicine composition to preparation of medicine for treating bronchial asthma
CN103656355A (en) Drug for curing pig paratyphus and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information
CB02 Change of applicant information

Address after: Room 1208, 12 / F, Haixing Plaza, Tanggu ocean science and Technology Park, Binhai New Area, Tianjin 300467

Applicant after: Hancui (Tianjin) Biotechnology Co.,Ltd.

Address before: 300000 Tianjin Binhai New Area Tanggu Marine Science and Technology Park, 15th Floor, Haixing Square Building 1

Applicant before: CHENBINGKUN (TIANJIN) BIOTECHNOLOGY Co.,Ltd.

RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20180511