CN108014175A - A kind of plant composition for being used to alleviate Rhinitis Symptoms - Google Patents
A kind of plant composition for being used to alleviate Rhinitis Symptoms Download PDFInfo
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- CN108014175A CN108014175A CN201711240322.3A CN201711240322A CN108014175A CN 108014175 A CN108014175 A CN 108014175A CN 201711240322 A CN201711240322 A CN 201711240322A CN 108014175 A CN108014175 A CN 108014175A
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- 206010039083 rhinitis Diseases 0.000 title claims abstract description 22
- 208000024891 symptom Diseases 0.000 title claims abstract description 21
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- 241000378544 Melaleuca quinquenervia Species 0.000 claims abstract description 21
- 244000283070 Abies balsamea Species 0.000 claims abstract description 18
- 235000007173 Abies balsamea Nutrition 0.000 claims abstract description 18
- 235000004710 Abies lasiocarpa Nutrition 0.000 claims abstract description 18
- 235000020748 rosemary extract Nutrition 0.000 claims abstract description 18
- 241000196324 Embryophyta Species 0.000 claims abstract description 17
- 235000020737 peppermint extract Nutrition 0.000 claims abstract description 17
- 238000000605 extraction Methods 0.000 claims description 49
- 244000246386 Mentha pulegium Species 0.000 claims description 19
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- 239000003921 oil Substances 0.000 claims description 18
- 238000001256 steam distillation Methods 0.000 claims description 15
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- 238000000034 method Methods 0.000 claims description 12
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- 239000007788 liquid Substances 0.000 claims description 7
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- 108010059892 Cellulase Proteins 0.000 claims description 5
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- 241000218646 Cedrus deodara Species 0.000 claims description 4
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- 241001529742 Rosmarinus Species 0.000 claims description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 3
- 238000006243 chemical reaction Methods 0.000 claims description 3
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- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 2
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- 238000007796 conventional method Methods 0.000 description 1
- IRAQOCYXUMOFCW-UHFFFAOYSA-N di-epi-alpha-cedrene Natural products C1C23C(C)CCC3C(C)(C)C1C(C)=CC2 IRAQOCYXUMOFCW-UHFFFAOYSA-N 0.000 description 1
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- SZGZILRQIYNODJ-UHFFFAOYSA-L disodium;7,12-dihydroquinoxalino[3,2-b]phenazine-2,9-disulfonate Chemical compound [Na+].[Na+].[O-]S(=O)(=O)C1=CC=C2N=C(C=C3C(NC4=CC=C(C=C4N3)S(=O)(=O)[O-])=C3)C3=NC2=C1 SZGZILRQIYNODJ-UHFFFAOYSA-L 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
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- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides a kind of plant composition for being used to alleviate Rhinitis Symptoms, it is made of the component of following volume parts:46 parts of 20 30 parts of cajeputtree extract, 15 25 parts of Himalaya Cedarwood extract, 15 25 parts of peppermint extract, 8 12 parts of balsam fir extract, 8 12 parts of Rosmarinus officinalis extract, 8 12 parts of cypress extract and Luo Wensha leaf extracts.The cajeputtree extract extracted by ad hoc fashion, Himalaya Cedarwood extract, peppermint extract, balsam fir extract, Rosmarinus officinalis extract, cypress extract and Luo Wensha leaf extracts are combined by the present invention, pass through mutual cooperation, the product prepared can be relieved the symptoms such as paroxysmal sneeze caused by allergic rhinitis, clear water sample nasal mucus, nasal obstruction and rhiocnesmus, positive effect, it is easy to use, Small side effects, can be with long-time service.
Description
Technical field
The invention belongs to medicines and health protection technical field, more particularly, to a kind of plant society for being used to alleviate Rhinitis Symptoms
Thing.
Background technology
Allergic rhinitis, that is, allergic rhinitis, after referring to atopic individuals contact allergen, is mainly situated between by immunoglobulin
Medium (mainly histamine) release led, and have the schneiderian membrance of the participations such as panimmunity competent cell and cell factor non-infectious
Inflammatory disease.Its necessary condition occurred has 3:Specific antigen is the material for causing organism immune response;Atopic individuals
I.e. so-called individual difference, allergic constitution;Specific antigen answers both type individuals to meet with spy.
Allergic rhinitis are a global health problems, can cause many diseases and disability, and cannot control
More, can only relief of symptoms.
Primary treatments have following several at present:Oral or nose spray antihistamine, is only applicable to mild intermittent and light
Spend continuation allergic rhinitis;Oral or nose spray Adrenal Glucocorticoid, effect is preferable, but long-time service drug effect can gradually drop
Low, side effect is larger, is only suitable for short;Immunotherapy needs the continued treatment of at least more than 2 years, and method is still immature,
Curative effect and side effect are still uncertain;External application nasal douche, effect unobvious and inconvenient to use.
The content of the invention
In view of this, the present invention is directed to propose a kind of plant composition for being used to alleviate Rhinitis Symptoms, effectively treats rhinitis,
Significant effect.
To reach above-mentioned purpose, the technical proposal of the invention is realized in this way:
A kind of plant composition for being used to alleviate Rhinitis Symptoms, is made of the component of following volume parts:
20-30 parts of cajeputtree extract, 15-25 parts of Himalaya Cedarwood extract, 15-25 parts of peppermint extract,
4-6 parts of 8-12 parts of balsam fir extract, 8-12 parts of Rosmarinus officinalis extract, 8-12 parts of cypress extract and Luo Wensha leaf extracts.
Further, the component by following volume parts forms:
23-28 parts of cajeputtree extract, 16-22 parts of Himalaya Cedarwood extract, 17-23 parts of peppermint extract,
4-6 parts of 8-11 parts of balsam fir extract, 8-10 parts of Rosmarinus officinalis extract, 10-12 parts of cypress extract and Luo Wensha leaf extracts.
Further, the component by following volume parts forms:
25 parts of cajeputtree extract, 20 parts of Himalaya Cedarwood extract, 20 parts of peppermint extract, balsam fir extraction
5 parts of 10 parts of thing, 10 parts of Rosmarinus officinalis extract, 10 parts of cypress extract and Luo Wensha leaf extracts.
Further, the extraction process of the cajeputtree extract is as follows:
Using supercritical CO2Abstraction technique, takes Cajeputtree Leaf, using temperature as 60 DEG C drying 0.5-1.5 it is small when, crushed 40
Mesh sieve, adds in extraction kettle, and sets CO2Circular flow is 25kg/h, and extracting pressure 30-35Mpa, temperature is 42-48 DEG C,
When extraction time is 2-3 small, entrainer is done using ethanol, its mass concentration is 60%, after extraction, isolated cajeputtree
Extract.
Further, the extraction process of the Himalaya Cedarwood extract is as follows:
Using steam distillation, Himalaya cedar leaf is taken, when using oven for drying 2 small at 65-70 DEG C, crushes, crosses 30
Mesh sieve, is fitted into distillation still, adds 10 times of water, when immersion 2-3 is small after be heated to seething with excitement, keep slightly boiling distillation 1 small under normal pressure
When, condensate liquid is collected, stops heating;After being cooled to room temperature, water-oil separating is carried out by oil water separator, obtains Himalaya snow
Loose extract.
Further, the extraction process of the peppermint extract is as follows:
Using steam distillation, peppermint branch and leaf are dried in the shade, adds in agitating ball mill, is 300- in rotating speed
Mechanical activation 5-10min under 800r/min, obtains peppermint powder;Above-mentioned peppermint powder is added into alembic, adds fibre
The plain enzyme of dimension and water, the weight of cellulase is peppermint powder weight 0.5-0.8%, is pressurizeed with slabstone so that water just steeped peppermint
Powder, when immersion 2-3 is small at normal temperatures, obtains extracting solution;Vapor is passed through from the bottom of alembic to heat extracting solution,
When extraction 1.5-2 is small after extracting solution boiling, mixed vapour is obtained;Mixed vapour is condensed by condenser, is obtained after condensation
Oil water mixture;Water-oil separating is carried out by oil water separator, obtains peppermint crude oil and water;Extracted again by extractor,
After layering, it is peppermint essential oil to separate upper strata.
Further, the extraction process of the balsam fir extract is as follows:
Using steam distillation, the bark, branch, leaf of balsam fir are broken into the little particle of 2-3cm, dried in the shade, crushed, mistake
20 mesh sieves, add 8-12 times of water, and when Dipping 2-3 is small, distillation pot bottom is passed through vapor heating, and mixed vapour condensation, obtains
Oil water mixture;Separated through separator, obtain crude extract;Filtered and removed water by anhydrous sodium sulfate, obtain balsam fir extract.
Further, the extraction process of the Rosmarinus officinalis extract is as follows:
Using CO2Supercritical extraction process, takes the cauline leaf of rosemary, and vacuum freeze-drying, crushes, and crosses 20 mesh sieves, adjusts CO2Follow
Circulation is 20-25kg/h, and extraction temperature is 40 DEG C, extracting pressure 20MPa, when extraction 1.5-2.5 is small, is pressed from both sides using ethanol
Band agent, its mass concentration are 60%, separating and extracting product and CO2, empty CO2, obtain Rosmarinus officinalis extract.
Further, the extraction process of the cypress extract is as follows:
Using supercritical CO2Abstraction technique, takes cypress leaf and fruit ball, and fruit ball is crushed, and confuses leaf using temperature as 60 DEG C of bakings
When dry 1.5-2.5 is small, 20 mesh sieves are crushed, are added in extraction kettle, and CO is set2Circular flow is 20kg/h, and extracting pressure is
10-17Mpa, temperature is 40 DEG C, when extraction time is 1.5-2.5 small, after extraction, and isolated cypress extract.
Further, the extraction process of the Luo Wensha leaf extracts is as follows:
Using steam distillation, take the leaf of Luo Wenshaye, using temperature as 60 DEG C of drying 0.5-1.5 it is small when, crushed 20
Mesh sieve, adds among reaction kettle, while adds 25% sodium chloride, connects distilling apparatus, carries out steam distillation, keeps slightly boiling
When state reflux 3 is small, continue to heat, collect condensate liquid, obtain oil water mixture;Water-oil separating is carried out by oil water separator,
Obtain Luo Wensha leaf extracts.
Cajeputtree extract, peppermint extract, balsam fir extract, Rosmarinus officinalis extract, cypress extract, Luo Wen
Contained firpene, laurene, limonene can speed up blood circulation in Sha's leaf extract, accelerate the absorption of active material.
Terpinolene contained in contained terpinene and cypress extract plays the role of anti-inflammatory in Luo Wensha leaf extracts.
It is contained in contained carypohyllene, Himalaya Cedarwood extract in Luo Wensha leaf extracts and peppermint extract
Cedrene play the role of antihistamine, suppress allergy, reduce mucosal tissue hyperemia and oedema, reduce nasal secretion.
Contained menthones in peppermint extract, contained atlantom is reduced in Himalaya Cedarwood extract
The effect of nasal membrane secretion.
Contained eucalyptus oil in cajeputtree extract, Rosmarinus officinalis extract, peppermint extract, Luo Wensha leaf extracts
Alcohol has bactericidal antiphlogistic, promotes blood circulation, and reduces the effect of nasal membrane secretion.
Relative to the prior art, the plant composition of the present invention for being used to alleviate Rhinitis Symptoms has the advantage that:
The plant composition of the present invention for being used to alleviate Rhinitis Symptoms, the cajeputtree that will be extracted by ad hoc fashion
Extract, Himalaya Cedarwood extract, peppermint extract, balsam fir extract, Rosmarinus officinalis extract, cypress extract
It is combined with Luo Wensha leaf extracts, by mutual cooperation, the product prepared can be relieved allergia nose
The symptom such as paroxysmal sneeze, clear water sample nasal mucus, nasal obstruction and rhiocnesmus caused by inflammation, positive effect is easy to use, and Small side effects can
With long-time service.
Embodiment
In addition to being defined, technical term used has universal with those skilled in the art of the invention in following embodiments
The identical meanings of understanding.Test reagent used, is routine biochemistry reagent unless otherwise specified in following embodiments;It is described
Experimental method, is conventional method unless otherwise specified.
With reference to embodiment, the present invention will be described in detail.
The extraction of cajeputtree extract:
Using supercritical CO2Abstraction technique, takes Cajeputtree Leaf, using temperature as 60 DEG C drying 1 it is small when, crushed 40 mesh sieves,
Add in extraction kettle, and CO is set2Circular flow is 25kg/h, and extracting pressure 33Mpa, temperature is 47 DEG C, and extraction time is 3
Hour, entrainer is done using ethanol, its mass concentration is 60%, after extraction, isolated cajeputtree extract.
The extraction of Himalaya Cedarwood extract:
Using steam distillation, Himalaya cedar leaf is taken, when using oven for drying 2 small at 70 DEG C, crushes, crosses 30 mesh
Sieve, is fitted into distillation still, add 10 times of water, immersion 2 it is small when after be heated to seething with excitement, under normal pressure keep slightly boiling distillation 1 it is small when, receipts
Collect condensate liquid, stop heating;After being cooled to room temperature, water-oil separating is carried out by oil water separator, Himalaya deodar is obtained and carries
Take thing.
The extraction of peppermint extract:
Using steam distillation, peppermint branch and leaf are dried in the shade, adds in agitating ball mill, is 500r/ in rotating speed
Mechanical activation 10min under min, obtains peppermint powder;By above-mentioned peppermint powder add alembic, add cellulase and
Water, the weight of cellulase is peppermint powder weight 0.6%, is pressurizeed with slabstone so that water just steeps excessively thin charged powders, in room temperature
It is lower immersion 3 it is small when, obtain extracting solution;Vapor is passed through from the bottom of alembic to heat extracting solution, after extracting solution boiling
Extract 1.5 it is small when, obtain mixed vapour;Mixed vapour is condensed by condenser, and oil water mixture is obtained after condensation;By
Oil water separator carries out water-oil separating, obtains peppermint crude oil and water;Extracted again by extractor, after layering, separate upper strata
As peppermint essential oil.
The extraction of balsam fir extract:
Using steam distillation, the bark, branch, leaf of balsam fir are broken into the little particle of 2-3cm, dried in the shade, crushed, mistake
20 mesh sieves, add 10 times of water, and when Dipping 2 is small, distillation pot bottom is passed through vapor heating, and mixed vapour condensation, obtains grease
Mixture;Separated through separator, obtain crude extract;Filtered and removed water by anhydrous sodium sulfate, obtain balsam fir extract.
The extraction of Rosmarinus officinalis extract:
Using CO2Supercritical extraction process, takes the cauline leaf of rosemary, and vacuum freeze-drying, crushes, and crosses 20 mesh sieves, adjusts CO2Follow
Circulation is 25kg/h, and extraction temperature is 40 DEG C, extracting pressure 20MPa, when extraction 2 is small, does entrainer using ethanol, its matter
It is 60% to measure concentration, separating and extracting product and CO2, empty CO2, obtain Rosmarinus officinalis extract.
The extraction of cypress extract:
Using supercritical CO2Abstraction technique, takes cypress leaf and fruit ball, and fruit ball is crushed, and confuses leaf using temperature as 60 DEG C of bakings
It is dry 2 it is small when, crushed 20 mesh sieves, add in extraction kettle, and CO is set2Circular flow is 20kg/h, extracting pressure 15Mpa,
Temperature is 40 DEG C, when extraction time is 2 small, after extraction, and isolated cypress extract.
The extraction of Luo Wensha leaf extracts:
Using steam distillation, take the leaf of Luo Wenshaye, using temperature as 60 DEG C of drying 1 it is small when, crushed 20 mesh sieves, add
Enter among reaction kettle, while add 25% sodium chloride, connect distilling apparatus, carry out steam distillation, keep slight boiling condition to return
Flow 3 it is small when, continue to heat, collect condensate liquid, obtain oil water mixture;Water-oil separating is carried out by oil water separator, obtains sieve
Literary Sha's leaf extract.
By the raw material of following volume parts, uniformly mixing is i.e. available:25 parts of cajeputtree extract, Himalaya deodar carry
Take 20 parts of thing, 20 parts of peppermint extract, 10 parts of balsam fir extract, 10 parts of Rosmarinus officinalis extract, 10 parts of cypress extract
With 5 parts of Luo Wensha leaf extracts.
Application method:
Appropriate product is taken to be applied in people, Jingming acupoint is to wing of nose both sides between fragrant cave, are touched 15-20 times, three times a day,
One week as a treatment course.
Clinical test statistics of the present invention is as follows:
Case | Recovery from illness | Significant curative effect | Effectively | It is invalid | It is efficient |
100 | 84 | 11 | 1 | 4 | 96.0% |
Wherein above curative effect determinate standard is:Treatment, which is not recurred in two course for the treatment of latter years, to be confirmed as fully recovering;Two treatments for the treatment of
Recurred in Cheng Houyi to be effective;State of an illness mitigation is effective after treating two courses for the treatment of;Without bright after two courses for the treatment of of treatment
It is aobvious be improved as it is invalid.
By the patient to 100 allergic rhinitis diseases by product of the present invention treat two courses for the treatment of after, share 4 people without
Effect, total effective rate reach 96.0%.
Use the effect of wherein more typical case further illustrates the present invention after the present invention.
Case one:Ma, female, people from Liaoning 32 years old, obtain allergic rhinitis 5 years, there is family's allergies, controlled for many years through hospital
It is invalid to treat, and aggravates year by year, when having an attack of one's old illness sneezing and flow clear tears, by the present invention treat two courses for the treatment of after rhinitis healing, in 1 year
Do not recur.
Case two:Certain is shut out, female, people from Chongqing, 24 years old, obtains allergic rhinitis 3 years after going to school to the north, no family's allergies,
Severe nasal blockage when having an attack of one's old illness, by rhinitis healing after the present invention two courses for the treatment of of treatment, does not recur in 1 year.
Case three:Lee, female, people from Sichuan, 22 years old, obtains allergic rhinitis 2 years after going to school to the north, no family's allergies,
Have a stuffy nose when having an attack of one's old illness, by rhinitis healing after the present invention two courses for the treatment of of treatment, recurred after 1 year, and use one treatment of product of the present invention
Rehabilitation after journey.
Case four:Yin certain, man, people from Shandong, 46 years old, obtains allergic rhinitis 8 years, and no family's allergies, various methods are for many years
Treatment is invalid, sneezes non-stop when having an attack of one's old illness and flow clear tears, seriously affects quality of life, and nose after two courses for the treatment of is treated by the present invention
Scorching rehabilitation, does not recur in 1 year.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
With within principle, any modification, equivalent replacement, improvement and so on, should all be included in the protection scope of the present invention god.
Claims (10)
- A kind of 1. plant composition for being used to alleviate Rhinitis Symptoms, it is characterised in that:It is made of the component of following volume parts:20-30 parts of cajeputtree extract, 15-25 parts of Himalaya Cedarwood extract, 15-25 parts of peppermint extract, glue are cold 4-6 parts of 8-12 parts of China fir extract, 8-12 parts of Rosmarinus officinalis extract, 8-12 parts of cypress extract and Luo Wensha leaf extracts.
- 2. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:By following parts by volume Several component compositions:23-28 parts of cajeputtree extract, 16-22 parts of Himalaya Cedarwood extract, 17-23 parts of peppermint extract, glue are cold 4-6 parts of 8-11 parts of China fir extract, 8-10 parts of Rosmarinus officinalis extract, 10-12 parts of cypress extract and Luo Wensha leaf extracts.
- 3. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:By following parts by volume Several component compositions:25 parts of cajeputtree extract, 20 parts of Himalaya Cedarwood extract, 20 parts of peppermint extract, balsam fir extract 10 Part, 10 parts of Rosmarinus officinalis extract, 10 parts of cypress extract and 5 parts of Luo Wensha leaf extracts.
- 4. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Cajeputtree extract Extraction process it is as follows:Using supercritical CO2Abstraction technique, takes Cajeputtree Leaf, using temperature as 60 DEG C drying 0.5-1.5 it is small when, crushed 40 mesh sieves, Add in extraction kettle, and CO is set2Circular flow is 25kg/h, and extracting pressure 30-35Mpa, temperature is 42-48 DEG C, extraction When time is 2-3 small, entrainer is done using ethanol, its mass concentration is 60%, after extraction, isolated cajeputtree extraction Thing.
- 5. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Himalaya deodar The extraction process of extract is as follows:Using steam distillation, Himalaya cedar leaf is taken, when using oven for drying 2 small at 65-70 DEG C, crushes, crosses 30 mesh sieves, Be fitted into distillation still, add 10 times of water, immersion 2-3 it is small when after be heated to seething with excitement, under normal pressure keep slightly boiling distillation 1 it is small when, receive Collect condensate liquid, stop heating;After being cooled to room temperature, water-oil separating is carried out by oil water separator, Himalaya deodar is obtained and carries Take thing.
- 6. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Peppermint extracts The extraction process of thing is as follows:Using steam distillation, peppermint branch and leaf are dried in the shade, adds in agitating ball mill, is 300-800r/ in rotating speed Mechanical activation 5-10min under min, obtains peppermint powder;Above-mentioned peppermint powder is added into alembic, adds cellulase And water, the weight of cellulase is peppermint powder weight 0.5-0.8%, is pressurizeed with slabstone and causes water just to steep excessively thin charged powders, When immersion 2-3 is small at normal temperatures, extracting solution is obtained;Vapor is passed through from the bottom of alembic to heat extracting solution, is extracted When extraction 1.5-2 is small after liquid boiling, mixed vapour is obtained;Mixed vapour is condensed by condenser, and grease is obtained after condensation Mixture;Water-oil separating is carried out by oil water separator, obtains peppermint crude oil and water;Extracted, be layered by extractor again Afterwards, it is peppermint essential oil to separate upper strata.
- 7. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Balsam fir extract Extraction process it is as follows:Using steam distillation, the bark, branch, leaf of balsam fir are broken into the little particle of 2-3cm, dried in the shade, crushed, cross 20 mesh Sieve, adds 8-12 times of water, and when Dipping 2-3 is small, distillation pot bottom is passed through vapor heating, and mixed vapour condensation, obtains grease Mixture;Separated through separator, obtain crude extract;Filtered and removed water by anhydrous sodium sulfate, obtain balsam fir extract.
- 8. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Rosmarinus officinalis extract Extraction process it is as follows:Using CO2Supercritical extraction process, takes the cauline leaf of rosemary, and vacuum freeze-drying, crushes, and crosses 20 mesh sieves, adjusts CO2Recycle stream It is 40 DEG C, extracting pressure 20MPa to measure as 20-25kg/h, extraction temperature, when extraction 1.5-2.5 is small, is carried secretly using ethanol Agent, its mass concentration are 60%, separating and extracting product and CO2, empty CO2, obtain Rosmarinus officinalis extract.
- 9. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Cypress extract Extraction process is as follows:Using supercritical CO2Abstraction technique, takes cypress leaf and fruit ball, and fruit ball is crushed, and confuses leaf using temperature as 60 DEG C of drying 1.5- 2.5 it is small when, crushed 20 mesh sieves, add in extraction kettle, and CO is set2Circular flow is 20kg/h, extracting pressure 10- 17Mpa, temperature is 40 DEG C, when extraction time is 1.5-2.5 small, after extraction, and isolated cypress extract.
- 10. the plant composition according to claim 1 for being used to alleviate Rhinitis Symptoms, it is characterised in that:Luo Wenshaye is carried Take the extraction process of thing as follows:Using steam distillation, take the leaf of Luo Wenshaye, using temperature as 60 DEG C of drying 0.5-1.5 it is small when, crushed 20 mesh sieves, Add among reaction kettle, while add 25% sodium chloride, connect distilling apparatus, carry out steam distillation, keep slight boiling condition Flow back 3 it is small when, continue to heat, collect condensate liquid, obtain oil water mixture;Water-oil separating is carried out by oil water separator, is obtained Luo Wensha leaf extracts.
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CN109464581A (en) * | 2019-01-18 | 2019-03-15 | 唐心尧 | A kind of composition and application thereof for alleviating Rhinitis Symptoms |
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Address after: Room 1208, 12 / F, Haixing Plaza, Tanggu ocean science and Technology Park, Binhai New Area, Tianjin 300467 Applicant after: Hancui (Tianjin) Biotechnology Co.,Ltd. Address before: 300000 Tianjin Binhai New Area Tanggu Marine Science and Technology Park, 15th Floor, Haixing Square Building 1 Applicant before: CHENBINGKUN (TIANJIN) BIOTECHNOLOGY Co.,Ltd. |
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Application publication date: 20180511 |