CN108008129A - CRP detection devices - Google Patents

CRP detection devices Download PDF

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Publication number
CN108008129A
CN108008129A CN201711462313.9A CN201711462313A CN108008129A CN 108008129 A CN108008129 A CN 108008129A CN 201711462313 A CN201711462313 A CN 201711462313A CN 108008129 A CN108008129 A CN 108008129A
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CN
China
Prior art keywords
pond
reaction tank
axis
reagent
mixed flow
Prior art date
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Withdrawn
Application number
CN201711462313.9A
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Chinese (zh)
Inventor
赵洪财
农柳华
杨龙
覃俊程
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Urit Medical Electronic Co Ltd
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Urit Medical Electronic Co Ltd
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Publication date
Application filed by Urit Medical Electronic Co Ltd filed Critical Urit Medical Electronic Co Ltd
Priority to CN201711462313.9A priority Critical patent/CN108008129A/en
Publication of CN108008129A publication Critical patent/CN108008129A/en
Withdrawn legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Optical Measuring Cells (AREA)

Abstract

The invention discloses a kind of CRP detection devices, including the reaction tank set based on engine base and according to pond, the reaction tank is equipped with sampling needle entry port and is communicated with reagent adding tube, it is described to be equipped with optical de-tection means according to pond and be communicated with cleaning pipe, reaction tank and according to being communicated with mixed flow tube between pond, described to be arranged on according to pond below the left or right side of reaction tank, the axis of reaction tank is vertical direction, and the axis of reaction tank is inclined to the left or to the right according to the axis in pond;The reagent adding tube and mixed flow tube are connected on the lower part of reaction tank and the side opposite with according to pond with identical height, and the mixed flow tube and cleaning pipe connection are opposite with reaction tank according on the side of pond and the connection height of mixed flow tube is more than the connection height of cleaning pipe.The addition efficiency of reagent and blood sample when the present invention improves CRP detections, avoids the cross contamination of reagent, reduces amount of reagent, effectively reduce single CRP testing costs.

Description

CRP detection devices
Technical field
The present invention relates to medical instrument, is specially a kind of CRP detection devices.
Background technology
In cellanalyzer, existing CRP (viral infection) measuring device is divided into two kinds:
One kind is to add hemolytic agent and blood sample by sampling needle, such a adding set, because using a sampling needle repeatedly into Row reagent gathers and blood specimen collection, have impact on the adding speed of reagent and the detection rates of CRP.
Another sampling needle only carries out sample collection and blood specimen collection to one of which reagent, while molten to one of which Blood agent has pre- addition, accelerates CRP reagent sample adding speeds, while improve CRP detection rates;But the preheating of this device All the time some reagent is preserved in mechanism, while preheats the hot environment that mechanism remains at 37 °, detects and fills in CRP Put long-time when not in use, the pilot scale agent of preheating mechanism is apt to deteriorate after long-time high-temperature storage, and inner cavity cleaning is difficult;To protect It is accurate to demonstrate,prove testing result, it will usually first the old reagent preheated in mechanism is rinsed well using a large amount of reagents, thus, is added The usage amount of single CRP test agents, adds testing cost.
Auspicious 5390CRP detection devices are such as stepped, there is disadvantage mentioned above, i.e.,:
Reagent in preheating apparatus remains at 37 °, when not in use for a long time, easily goes bad, and cleaning is difficult, And need to clean it using substantial amounts of reagent before detecting every time, add single sample testing cost.
The content of the invention
In view of the deficiencies of the prior art, the technical problems to be solved by the invention are to propose a kind of various reagents that reduce to disappear Consumption, the CRP detection devices for reducing testing cost.
The CRP detection devices of above-mentioned technical problem can be solved, its technical solution includes the reaction tank set based on engine base With according to pond, the reaction tank is equipped with sampling needle entry port and is communicated with reagent adding tube, described to be equipped with light according to pond Learn testing agency and be communicated with cleaning pipe, reaction tank and (realize reaction tank and according between pond according to mixed flow tube is communicated between pond Fluid exchange), except that the engine base is equipped with by the heat transfer preheating reaction tank and heating arrangements according to pond, institute Engine base is stated to be made of the metal material of good heat-transfer.
It is with the technical solution for avoiding reagent contamination from taking to improve addition efficiency:The reaction tank according to pond with being arranged on On same vertical plane, described to be arranged on according to pond below the left or right side of reaction tank, the axis of reaction tank is vertical direction, is contrasted The axis in pond is inclined to the axis of reaction tank to the left or to the right;The reagent adding tube is connected with mixed flow tube with identical height The lower part of reaction tank and with according on the opposite side in pond, the mixed flow tube and cleaning pipe connection are contrasted in opposite with reaction tank On the side of pond and mixed flow tube connection height be more than cleaning pipe connection height.
In said structure, the reagent adding tube and mixed flow tube are main to consider processing with identical height connected reaction pond It is convenient, while when cleaning reaction tank, the reagent that liquid is easier to add reagent on pipe addition cleans up, and reduces and intersects dirt Dye;The connection of the mixed flow tube is highly more than cleaning pipe, its main cause is to consider to eliminate problem according to bubble in pond, from lower past Upper plus cleaning liquid, can effectively exclude to contrast the bubble in pond, reduce interference of the bubble to test result, ensure test knot The accuracy of fruit.
The axis deviation according to pond in reaction tank axis optimized angle between 20 °~40 °.
The axis deviation according to pond is 30 ° in the best angle of reaction tank axis.
Conventionally, the sampling needle entry port is arranged on the upper port of reaction tank.
Conventionally, the optical de-tection means are in the upper port according to pond.
Beneficial effects of the present invention:
1st, in CRP structure of the detecting device of the present invention, since reaction tank side is provided with reagent inlet, can be added by reagent Pipe is added to add reagent, the addition efficiency of reagent and blood sample when improving CRP detections, because reducing sampling needle takes reagent Number, can be to avoid reagent cross contamination.
2nd, in structure of the present invention, heating arrangements are only heated to reaction tank and according to pond, and CRP detection reagents are added to reaction tank Before remain room temperature, meet reagent preservation condition, though for a long time without using instrument carry out CRP data tests, will not be right CRP detection reagents are heated, and reduce amount of reagent, effectively reduce single CRP testing costs.
Brief description of the drawings
Fig. 1 is the structure diagram of one embodiment of the present invention.
Fig. 2 is the structure diagram of reaction tank in Fig. 1.
Figure number identifies:1st, engine base;2nd, reaction tank;2-1, sampling needle entry port;3rd, according to pond;4th, optical de-tection means; 5th, heating arrangements;6th, reagent adding tube;7th, cleaning pipe;8th, mixed flow tube.
Embodiment
Illustrated embodiment is described further technical scheme below in conjunction with the accompanying drawings.
The structure of CRP detection devices of the present invention includes reaction tank 2 and according to pond 3, vertical (its lumen shaft of the reaction tank 2 Line is vertical) upper right side of engine base 1 is arranged on, it is described to exist together according to pond 3 with reaction tank 2 on a vertical plane and in a left side for reaction tank 2 Lower section is arranged on engine base 1, and optical de-tection means 4 are provided with and according to the upper port deflection to the left in pond 3 according to the upper port in pond 3 30 ° and with the axis of reaction tank 2 formed angle (this measure is that bubble is accumulated at the optical transmission window for preventing optical de-tection means 4 so that Cause the CRP test datas unstable), it is communicated with mixed flow tube 8 and cleaning pipe 7 according to the sidepiece in pond 3;The upper end of the reaction tank 2 Mouth is set to sampling needle entry port 2-1, and the lower part of reaction tank 2 is communicated with reagent adding tube 6, the reagent adding tube 6 and engine base 1 Reagent addition mechanism connection, as shown in Figure 1.
The mixed flow tube 8 and cleaning pipe 7 connect it is opposite with reaction tank 2 according on 3 side of pond and mixed flow tube 8 connection Highly more than the connection height of cleaning pipe 7;The reaction tank 2 is up-small and down-big double sectioned column body, the sampling needle upstream end Mouth 2-1 is in the upper port of upper section reaction tank 2, and the reagent adding tube 6 and mixed flow tube 8 are connected in lower section instead with identical height Answer the lower part in pond 2 and with according on the opposite side in pond 3, the connected entrance of reagent adding tube 6 and mixed flow tube 8 and lower section reaction tank 2 Position open up to be left and right, as shown in Figure 2.
The engine base 1 is made of the aluminum alloy materials of good heat-transfer, reaction tank 2 and according on the engine base 1 between pond 3 Equipped with heating arrangements 5, by the conduction of engine base 1, the temperature of the heating arrangements 5 can be at the same time to 2 He of reaction tank by conduction Be preheated to temperature according to pond 3 as 37 °, so as to reach the optimum state of CRP detections;It is equipped with and passes through in the heating arrangements 5 Temperature detect switch (TDS) controls the temperature sensor of heating plate heating-up temperature, accurately controls reaction tank 2 by temperature sensor and contrasts The temperature in pond 3, so that it is guaranteed that detecting the controllable of fluid temperature when detecting every time.

Claims (6)

1.CRP detection devices, including the reaction tank (2) that is set based on engine base (1) and according to pond (3), are set on the reaction tank (2) There is sampling needle entry port (2-1) and be communicated with reagent adding tube (6), it is described to be equipped with optical de-tection means (4) according to pond (3) Be communicated with cleaning pipe (7), reaction tank (2) and according to being communicated with mixed flow tube (8) between pond (3), it is characterised in that:The engine base (1) it is equipped with and reaction tank (2) and the heating arrangements (5) according to pond (3) is preheated by heat transfer, the engine base (1) is using heat transfer The good metal material of performance makes.
2. CRP detection devices according to claim 1, it is characterised in that:The reaction tank (2) according to pond (3) with being arranged on On same vertical plane, described to be arranged on according to pond (3) below the left or right side of reaction tank (2), the axis of reaction tank (2) is vertical Direction, the axis of reaction tank (2) is inclined to according to the axis of pond (3) to the left or to the right;The reagent adding tube (6) and mixed flow tube (8) with identical height connection the lower part of reaction tank (2) and with according on pond (3) opposite side, the mixed flow tube (8) and Cleaning pipe (7) connection is opposite with reaction tank (2) according on pond (3) side and the connection of mixed flow tube (8) highly is more than and cleans Manage the connection height of (7).
3. CRP detection devices according to claim 2, it is characterised in that:The axis deviation according to pond (3) is in reaction The angle of pond (2) axis is 20 °~40 °.
4. CRP detection devices according to claim 3, it is characterised in that:The axis deviation according to pond (3) is in reaction The angle of pond (2) axis is 30 °.
5. the CRP detection devices according to any one in Claims 1 to 4, it is characterised in that:The sampling needle upstream end Mouth (2-1) is in the upper port of reaction tank (2).
6. the CRP detection devices according to any one in Claims 1 to 4, it is characterised in that:The optical de-tection means (4) it is in the upper port according to pond (3).
CN201711462313.9A 2017-12-28 2017-12-28 CRP detection devices Withdrawn CN108008129A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711462313.9A CN108008129A (en) 2017-12-28 2017-12-28 CRP detection devices

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711462313.9A CN108008129A (en) 2017-12-28 2017-12-28 CRP detection devices

Publications (1)

Publication Number Publication Date
CN108008129A true CN108008129A (en) 2018-05-08

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CN201711462313.9A Withdrawn CN108008129A (en) 2017-12-28 2017-12-28 CRP detection devices

Country Status (1)

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CN (1) CN108008129A (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010002209A (en) * 2008-06-18 2010-01-07 Horiba Ltd Body fluid sample analyzer
CN203981594U (en) * 2014-07-01 2014-12-03 深圳迈瑞生物医疗电子股份有限公司 A kind of CRP measures assembly
CN104713816A (en) * 2015-02-04 2015-06-17 深圳市帝迈生物技术有限公司 Whole blood CRP detection apparatus, method thereof, and blood cell analyzer
CN105699380A (en) * 2016-03-23 2016-06-22 深圳市帝迈生物技术有限公司 Analysis equipment and method for simultaneously measuring CRP (C-Reactive Protein) and blood routine
CN207703870U (en) * 2017-12-28 2018-08-07 桂林优利特医疗电子有限公司 CRP detection devices

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010002209A (en) * 2008-06-18 2010-01-07 Horiba Ltd Body fluid sample analyzer
CN203981594U (en) * 2014-07-01 2014-12-03 深圳迈瑞生物医疗电子股份有限公司 A kind of CRP measures assembly
CN104713816A (en) * 2015-02-04 2015-06-17 深圳市帝迈生物技术有限公司 Whole blood CRP detection apparatus, method thereof, and blood cell analyzer
CN105699380A (en) * 2016-03-23 2016-06-22 深圳市帝迈生物技术有限公司 Analysis equipment and method for simultaneously measuring CRP (C-Reactive Protein) and blood routine
CN207703870U (en) * 2017-12-28 2018-08-07 桂林优利特医疗电子有限公司 CRP detection devices

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Application publication date: 20180508

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