CN108004100A - A kind of preparation method of Shennong medicinal liquor - Google Patents

A kind of preparation method of Shennong medicinal liquor Download PDF

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Publication number
CN108004100A
CN108004100A CN201711330343.4A CN201711330343A CN108004100A CN 108004100 A CN108004100 A CN 108004100A CN 201711330343 A CN201711330343 A CN 201711330343A CN 108004100 A CN108004100 A CN 108004100A
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CN
China
Prior art keywords
weight
parts
medicinal liquor
shennong
dregs
Prior art date
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Pending
Application number
CN201711330343.4A
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Chinese (zh)
Inventor
曾希望
石伟
沈新伦
黄军陆
曾浩
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HUBEI FUREN JINSHEN PHARMACEUTICAL Co Ltd
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HUBEI FUREN JINSHEN PHARMACEUTICAL Co Ltd
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Priority to CN201711330343.4A priority Critical patent/CN108004100A/en
Publication of CN108004100A publication Critical patent/CN108004100A/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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Abstract

The invention discloses a kind of preparation method of Shennong medicinal liquor, comprise the following steps:Step 1: after each raw material is smashed or cut into slices respectively, it is uniformly mixed, obtains Traditional Chinese drug mixture;Step 2: by sucrose and white spirit mixed, sugar wine solution is made, and sugar wine solution is added in Chinese prescription, closed immersion, filters, obtains the first soak and first dregs of a decoction, it is spare;Step 3: white wine is added in first dregs of a decoction, after closed immersion, filtering, obtains the second soak and second dregs of a decoction, spare;Step 4: second dregs of a decoction that step 3 is obtained are squeezed the juice and filtered, retain filtrate, and be uniformly mixed with first soak and the second soak, stand to clarifying, take supernatant liquor, that is, obtain the Shennong medicinal liquor.The present invention provides a kind of preparation method for the Shennong medicinal liquor that middle the effective elements of the medicine is sufficiently extracted.

Description

A kind of preparation method of Shennong medicinal liquor
Technical field
The present invention relates to medicinal liquor preparation method field.A kind of it is more particularly related to preparation side of Shennong medicinal liquor Method.
Background technology
The effect of Shennong medicinal liquor has expelling wind and clearing away cold, promoting blood circulation and removing blood stasis, relaxing tendons and activating collaterals.Suitable for wind-cold-dampness arthralgia, on swelling and pain, Muscular strain, at present, the osteoarthropathy such as cervical spondylosis, scapulohumeral periarthritis, pain in waist and lower extremities, chronic strain and rheumatoid arthritis be because Bone and perienchyma's inflammation to swelling, denaturation, deformation cause in great pain or paralysis.Current this kind of patient crowd is huge, severe one Be paralyzed in bed, cannot taking care of oneself for having causes serious burden to family life, painful be most patient also to live, work Make, slight illness brings many pains to them, so that quality of life declines, 80% women enters after person in middle and old age all can be with psoas Strain, osteoproliferation etc., rheumatoid arthritis are also one of national or even global illness for being difficult to cure, shoulder cervical vertebra Patient is even more the multiple occupational disease of current computer age, and patient largely takes Western medicine analgesia to mitigate slight illness, certainly now Pharmaceuticals industry is constantly progressive, and traditional Chinese and western medicine has the medicine to this treatment, and Western medicine has the advantages of quick, of low cost, but its is right Liver kidney and stomach have larger side effect, when particularly using some hormone medicines to alleviate the state of an illness, although joint is substantially subsided a swelling, Activity is nimble to solve pain problem, and the state of an illness is improved to greatest extent.But continue medication, curative effect reduces on the contrary, i.e., Make increased dosage amount also of no avail, the benefit for bringing quite a few patient to obtain therewith, such as symptom mitigate, and have not offset medicine Harm caused by thing toxic side effect.As bulimia, moon shaped face, buffalo hump, central obesity, hirsutism, acne, oedema, The toxic side effects such as hypertension, diabetes, paramenia, adrenal cortex underactivity, osteoporosis come one after the other.Therefore, it is long The consequence of phase hormone abuse, or even than disease inherently more seriously with threat to life.And Chinese herbal medicine is comparatively safe, the efficacy of a drug is gently steady It is fixed, and have regulatory function to organ, make uncomfortable progressively to be corrected.For many years, China also has some to match somebody with somebody with Chinese medicine Such preparation of the different dosage forms of system, as the tiger bone in one's early years chases after wind wine, cortex acanthopanacis medicinal liquor, leopard bone medicinal liquor and great thatch medicine in recent years Wine etc., for preceding 3 kinds of wine because various factors has all stopped production, great thatch medicinal liquor claims the history for having centuries, is also all traditional using China Chinese medicine is brewed to be formed, and has long-term clinical verification.Shennong medicinal liquor is the knot based on summarizing the proved recipe among the people for continuing to use for more than 30 years Close modern new medication principle and supplemented amendment and be composed, be allowed to that prescription compatibility is more perfect and science, selected is 43 tastes Chinese herbal medicine, and the verification of the clinical practice through more than 20 years, have obtained to rheumatic Bi syndrome, painful swelling of joints, muscular strain, scapulohumeral periarthritis, class The effective percentage such as rheumathritis 89.6%, the treatment data of obvious effective rate 48.5%, there is significant expelling wind and removing dampness, promoting blood circulation and removing blood stasis, easypro The effect of muscle is active.Wherein cure have all the year round bed can't take care of oneself and also for a long time by taking Western medicine and amcinonide The patient that thing maintains, by even served with after 10 jin of medicinal liquor, arthralgia is clearly better, and knee joint swelling disappears, and function of joint is extensive Again until can walk.1 week arthralgia mitigates after most patients take medicinal liquor, and after taking 4 jin of medicinal liquor, symptom has different journeys Degree is alleviated, and function, which improves to pain, to disappear.Pharmacological testing proves there is obvious anti-inflammatory effect and analgesic activity and humoral immunity Inhibitory action;Toxicity test is proved without cumulative effect, on hepatic and renal function and blood picture without influence;Clinical trial proves the medicinal liquor curative effect Well, securely and reliably.The achievement and in June, 1985 by the assessment of result of Hubei Department of Public Health of Shanxi Province, identify the medicinal liquor quality and Therapeutic effect has the advanced level of domestic similar product.Come because of respect for the fame again by the case observation in more than 20 years, healing after identification Patient with severe symptoms nearly thousand, most of associated patients obtain the effect of preferable after taking, and medicinal liquor quality reaches Chinese Pharmacopoeia Test stone under version vina item in 1977.
It is that simple soaking in Chinese liquor is made to prepare the method for Shennong medicinal liquor at present, its be difficult centering the effective elements of the medicine into Row sufficiently extraction.
The content of the invention
A kind of preparation side of the Shennong medicinal liquor sufficiently extracted the object of the present invention is to provide middle the effective elements of the medicine Method.
In order to realize these purposes and further advantage according to the present invention, there is provided a kind of preparation method of Shennong medicinal liquor, Comprise the following steps:
Step 1: by the berba aristolochiae mollissimae of 200-350 parts by weight, the Ligusticum wallichii of 200-350 parts by weight, 200-350 parts by weight pellet Ginseng, windproof, 200-350 parts by weight the costus root of 200-350 parts by weight, the asiatic toddalia root-bark of 200-350 parts by weight, 200-300 weights Measure the caulis trachelospermi of part, the bark of eucommia of 100-300 parts by weight, the cortex acanthopanacis of 100-300 parts by weight, 100-300 parts by weight geranium wilfordii, The sargentodoxa cuneata of 100-300 parts by weight, the Sambucus chinensis of 100-300 parts by weight, the caraway tea of 100-300 parts by weight, 100-300 weight Part giant knotweed, the buckwheat pseudo-ginseng of 100-300 parts by weight, the Ciliatenerve Knotweed Root of 100-300 parts by weight, 100-300 parts by weight the tiger root and stem of certain plants, The Herba Polygoni Runcinati of 100-300 parts by weight, the radix bupleuri of 100-300 parts by weight, the Angelica sinensis of 50-200 parts by weight, the iron of 50-200 parts by weight Shoulder pole, the chrysanthemum pseudo-ginseng of 50-200 parts by weight, the playing both sides of the street of 50-200 parts by weight, the radix aconiti agrestis of 50-200 parts by weight, 50-200 weight The blackberry lily, the wooden comb of 50-200 parts by weight, the reticulate millettia of 50-200 parts by weight, the rhizoma atractylodis of 50-200 parts by weight, 50-200 weights of part Measure the Dysosma versipellis of part, the cold water pellet of 50-200 parts by weight, the root of Chinese clematis of 50-200 parts by weight, 50-200 parts by weight lycopodium calvatum, The levisticums of 10-100 parts by weight, 10-100 parts by weight climb rock perfume, the alangium of 10-100 parts by weight, Xu of 10-100 parts by weight Long minister in ancient times, the uncaria of 10-100 parts by weight, 10-100 parts by weight calculate sub- root, the Coniogramme japonica (Thunb.) Diels of 10-100 parts by weight, 10-100 weight The root of bidentate achyranthes for measuring the paris polyphylla of part, the safflower of 10-100 parts by weight, the pseudo-ginseng of 1-20 parts by weight and 1-20 parts by weight is cut respectively Crush, and be uniformly mixed after piece or segment, obtain Chinese prescription, be placed in sterilizing cabinet after disinfection, it is spare;Traditional Chinese drug mixture
Step 2: the white wine 1-10 in mass ratio by sucrose with alcoholic strength for 50-60%:100 ratio mixing, is made sugar Wine solution, and by the sugar wine solution be added in step 1 sterilize after Chinese prescription in, it is closed immersion 15-20 days after, mistake Filter, obtains the first soak and first dregs of a decoction, spare;
Step 3: the white wine that alcoholic strength is 50-60% is added in first dregs of a decoction that step 2 obtains, closed immersion After 15-20 days, filtering, obtains the second soak and second dregs of a decoction, spare;
Step 4: second dregs of a decoction that step 3 is obtained are squeezed the juice and filtered, retain filtrate, and with first soak and Second soak is uniformly mixed, and is stood to clarifying, is taken supernatant liquor, that is, obtain the Shennong medicinal liquor.
The Shennong medicinal liquor that the present invention is prepared, except for drink it is for oral administration in addition to, can also be made into liniment or spray, directly Connect and act on affected part, can also play it is promoting blood circulation and removing blood stasis, the effect of relaxing tendons and activating collaterals.
Preferably, in a kind of preparation method of Shennong medicinal liquor, the Chinese prescription is obtained in the step 1 Afterwards, after first the Chinese prescription is dispensed into multiple gauze bags, the gauze bag sack is tightened, then be placed in sterilizing cabinet Disinfection.
Preferably, in a kind of preparation method of Shennong medicinal liquor, in the step 4 by the filtrate with it is described Before first soak and the second soak are uniformly mixed, first first soak and the second soak are uniformly mixed, stood To clarification.
Preferably, in a kind of preparation method of Shennong medicinal liquor, in the step 2 and step 3, medicinal liquor is used Leaching device soaks the Chinese prescription and first dregs of a decoction.
Preferably, in a kind of preparation method of Shennong medicinal liquor, the medicinal liquor leaching device includes body, rotating cylinder And shaft:
The body has inner cavity;
The rotating cylinder is the cylindrical shape of lower ending opening, it is vertically arranged in the inner cavity, on the lateral wall of the rotating cylinder Multiple through holes are arranged at intervals with, multiple first protrusions are arranged at intervals with its madial wall, the bottom wall of the inner cavity is equipped with and institute The corresponding toroidal cavity in rotating cylinder lower end is stated, the lower end of the rotating cylinder is spindle rotationally arranged in the toroidal cavity, described The upper end of rotating cylinder is coaxially arranged with a round bar, and the upper end of the round bar passes through the roof of the inner cavity and extends to described in vitro Portion, is provided with the first motor above the body, the output shaft of first motor is connected with the upper end of the round bar, described The output shaft of first motor drives the round bar and drives the rotating cylinder to be rotated in the interior intracavitary;
The shaft is vertically arranged in the inner cavity and inside the rotating cylinder, and is arranged at intervals with its lateral wall Multiple second is raised, and the lower end of the shaft is pierced by the bottom wall of the inner cavity and extends to the body exterior, the body Lower section is provided with the second motor, and the output shaft of second motor is connected with the lower end of the shaft, second motor it is defeated Shaft drives the shaft to be rotated in the rotating cylinder, and the direction of shaft rotation and the direction phase of the drum rotation Instead.
Preferably, in a kind of preparation method of Shennong medicinal liquor, being provided with the through hole prevents the dregs of a decoction from passing through Filter screen.
Preferably, in a kind of preparation method of Shennong medicinal liquor, the upper end of the body is provided with and the inner cavity The first notch passed through for Chinese medicine of connection, the upper end of the rotating cylinder is provided with corresponding with first notch to be passed through for Chinese medicine Second notch, during the drum rotation, second notch can turn to first bottom of the gap.
Preferably, in a kind of preparation method of Shennong medicinal liquor, the body upper end is provided with and the inner cavity The feed inlet of connection, its lower end are provided with discharge port in communication with the inner cavity.
Preferably, in a kind of preparation method of Shennong medicinal liquor, in the step 4, dregs pressing device is used Squeeze the juice to second dregs of a decoction, the dregs pressing device is oppositely arranged including squeezing groove, material baffle, movable plate and two Servo electric cylinders:
The squeezing groove is vertically arranged, its inner hollow and upper and lower side is open is described to squeeze in groove close to the position of its lower end Level removably be equipped with material baffle, be arranged at intervals with the material baffle it is multiple confessions squeeze the juice through liquid-leaking nozzle;
The servo electric cylinders are arranged on below the movable plate, and its guide rod is vertically arranged, two servo electric cylinders Guide rod is connected with the movable plate respectively, and two guide rods drive the movable plate to move up and down;
The movable plate is arranged on above the squeezing groove, and pressure corresponding with the squeezing groove is provided with below the movable plate Head, the pressure head is moved downward to the squeezing groove under the driving of two servo electric cylinders and the slot bottom with squeezing groove offsets, or It is moved upward to the top of the squeezing groove.
Preferably, in a kind of preparation method of Shennong medicinal liquor, in the step 4, filled using ceramic membrane filter The juice obtained after squeezing the juice to second dregs of a decoction is put to filter.
Preferably, in a kind of preparation method of Shennong medicinal liquor, the ceramic membrane filter device includes ceramic membrane Filter and pressue device, the purpose ceramic-film filter top are equipped with feed inlet, and lower end is connected with discharge nozzle, the pressue device By hose with being connected to and in communication with inside the purpose ceramic-film filter.
The preparation method of the Shennong medicinal liquor of the present invention more can extract the active ingredient in Chinese medicine so that system Standby Shennong medicinal liquor expelling wind and clearing away cold, it is promoting blood circulation and removing blood stasis, it is the effect of relaxing tendons and activating collaterals and better.
Further advantage, target and the feature of the present invention embodies part by following explanation, and part will also be by this The research and practice of invention and be understood by the person skilled in the art.
Brief description of the drawings
Fig. 1 is the structure diagram of medicinal liquor leaching device of the present invention;
Fig. 2 is the structure diagram of dregs pressing device of the present invention;
Fig. 3 is the structure diagram of ceramic membrane filter device of the present invention.
Embodiment
The present invention is described in further detail below, to make those skilled in the art can be according to this with reference to specification word Implement.
It should be noted that experimental method described in following embodiments, is conventional method unless otherwise specified, institute Reagent and material are stated, unless otherwise specified, is commercially obtained;In the description of the present invention, term " transverse direction ", " vertical To ", " on ", " under ", "front", "rear", "left", "right", " vertical ", " level ", " top ", " bottom ", " interior ", the instruction such as " outer " side Position or position relationship are based on orientation shown in the drawings or position relationship, are for only for ease of the description present invention and simplify description, It is not instruction or implies signified device or element there must be specific orientation, with specific azimuth configuration and operation, because This is not considered as limiting the invention.
<Embodiment 1>
A kind of preparation method of Shennong medicinal liquor, comprises the following steps:
Step 1: by the berba aristolochiae mollissimae of 200 parts by weight, the Ligusticum wallichii of 200 parts by weight, the Radix Salviae Miltiorrhizae of 200 parts by weight, 200 parts by weight Windproof, 200 parts by weight costus root, the asiatic toddalia root-bark of 200 parts by weight, the caulis trachelospermi of 200 parts by weight, 100 parts by weight the bark of eucommia, The cortex acanthopanacis of 100 parts by weight, the geranium wilfordii of 100 parts by weight, the sargentodoxa cuneata of 100 parts by weight, the Sambucus chinensis of 100 parts by weight, 100 weights Measure the caraway tea of part, the giant knotweed of 100 parts by weight, the buckwheat pseudo-ginseng of 100 parts by weight, the Ciliatenerve Knotweed Root of 100 parts by weight, 100 parts by weight The tiger root and stem of certain plants, the Herba Polygoni Runcinati of 100 parts by weight, the radix bupleuri of 100 parts by weight, the Angelica sinensis of 50 parts by weight, the fringed iris herb of 50 parts by weight, 50 The chrysanthemum pseudo-ginseng of parts by weight, the playing both sides of the street of 50 parts by weight, the radix aconiti agrestis of 50 parts by weight, the blackberry lily of 50 parts by weight, 50 parts by weight wooden comb, The reticulate millettia of 50 parts by weight, the rhizoma atractylodis of 50 parts by weight, the Dysosma versipellis of 50 parts by weight, the cold water of 50 parts by weight are red, 50 parts by weight The root of Chinese clematis, the lycopodium calvatum of 50 parts by weight, the levisticum of 10 parts by weight, 10 parts by weight climb rock perfume, the alangium of 10 parts by weight, 10 weights The amount paniculate swallowwort of part, the uncaria of 10 parts by weight, 10 parts by weight calculate sub- root, the Coniogramme japonica (Thunb.) Diels of 10 parts by weight, the seven of 10 parts by weight Leaf a flower, the safflower of 10 parts by weight, the root of bidentate achyranthes of the pseudo-ginseng of 1 parts by weight and 1 parts by weight cut into slices respectively or segment after crush, and mix Close uniformly, obtain Chinese prescription, be placed in sterilizing cabinet after disinfection, it is spare;
Step 2: by the white wine in mass ratio 1 that sucrose and alcoholic strength are 50%:100 ratio mixing, it is molten to be made sugar wine Liquid, and by the sugar wine solution be added in step 1 sterilize after Chinese prescription in, it is closed immersion 15 days after, filtering, obtain First soak and first dregs of a decoction, it is spare;
Step 3: first dregs of a decoction that step 2 is obtained are added in the white wine that alcoholic strength is 50%, closed immersion 15 days Afterwards, filter, obtain the second soak and second dregs of a decoction, it is spare;
Step 4: second dregs of a decoction that step 3 is obtained are squeezed the juice and filtered, retain filtrate, and with first soak and Second soak is uniformly mixed, and is stood to clarifying, is taken supernatant liquor, that is, obtain the Shennong medicinal liquor;
Wherein, before the filtrate is uniformly mixed with first soak and the second soak, first described first is soaked Bubble liquid and the second soak are uniformly mixed, and are stood to clarification;In the step 2 and step 3, using medicinal liquor leaching device to institute State Chinese prescription and first dregs of a decoction are soaked, as shown in Figure 1, medicinal liquor leaching device includes body 1, rotating cylinder 2 and shaft 3:
The body 1 has inner cavity 11;
The rotating cylinder 2 is the cylindrical shape of lower ending opening, it is vertically arranged in the inner cavity 11, the outside of the rotating cylinder 2 Multiple through holes 21 are arranged at intervals with wall, multiple first protrusions 22, the bottom wall of the inner cavity 11 are arranged at intervals with its madial wall Toroidal cavity 12 corresponding with 2 lower end of rotating cylinder is equipped with, the lower end of the rotating cylinder 2 is spindle rotationally arranged in the annulus In connected in star 12, the upper end of the rotating cylinder 2 is coaxially arranged with a round bar 23, and the upper end of the round bar 23 passes through the inner cavity 11 Roof is simultaneously extended to outside the body 1, and the top of the body 1 is provided with the first motor 24, first motor 24 it is defeated Shaft is connected with the upper end of the round bar 23, and the output shaft of first motor 24 drives the round bar 23 and drives the rotating cylinder 2 rotate in the inner cavity 11;
The shaft 3 is vertically arranged in the inner cavity 11 and inside the rotating cylinder 2, and interval is set on its lateral wall Multiple second protrusions 31 are equipped with, the lower end of the shaft 3 is pierced by the bottom wall of the inner cavity 11 and extends to outside the body 1, The lower section of the body 1 is provided with the second motor 32, and the output shaft of second motor 32 is connected with the lower end of the shaft 3, The output shaft of second motor 32 drives the shaft 3 to be rotated in the rotating cylinder 2, and the direction that rotates of the shaft 3 with The direction that the rotating cylinder 2 rotates is opposite.
In the present embodiment, as shown in Figure 1, setting rotating cylinder 2 and shaft 3 in inner cavity 11, and shaft 3 is arranged on rotating cylinder 2 In, multiple through holes 21 are arranged at intervals with the lateral wall of rotating cylinder 2 so that the inside of rotating cylinder 2 is connected with cavity, in use, by Chinese medicine Prescription or first dregs of a decoction are placed in rotating cylinder 2, and the first sugar wine solution or the second sugar wine solution are injected in oral cavity, and the first motor 24 drives Turn cylinder 2 rotates in cavity, 32 drive shaft 3 of the second motor in 2 inside shaft 3 of rotating cylinder, wherein, the first motor 24 and second Motor 32 can be by being fixed on the top and bottom of body 1;It is multiple in multiple first protrusions 22 and shaft 3 on rotating cylinder 2 Second protrusion 31 can drive the solution on its periphery to rotate in rotation process, and turn of the first protrusion 22 and the second protrusion 31 Dynamic direction is on the contrary, it causes the rotation direction of periphery solution also on the contrary, can strengthen in rotating cylinder 2 solution to Chinese prescription or first The impact force of the dregs of a decoction, so that the active ingredient in Chinese prescription or first dregs of a decoction more enters the first sugar wine solution faster Or second in sugar wine solution, to improve the effect of herbal medicine immersion and efficiency.
Wherein, it is provided with the filter screen for preventing the dregs of a decoction from passing through in the through hole 21.
In the present embodiment, the filter screen for preventing the dregs of a decoction from passing through is provided with through hole 21, can be to avoid the Chinese medicine in rotating cylinder 2 Prescription or first dregs of a decoction are flowed to from through hole 21 outside rotating cylinder 2, and by strainer, the solution inside and outside a permission rotating cylinder 2 is exchanged with each other, and The Chinese prescription of solid or first dregs of a decoction can only be stayed in rotating cylinder 2.
Wherein, the upper end of the body 1 is provided with the first notch 13 passed through for Chinese medicine connected with the inner cavity 11, described The upper end of rotating cylinder 2 is provided with the second notch 25 passed through for Chinese medicine corresponding with first notch 13,2 rotation process of rotating cylinder In, second notch 25 can turn to the lower section of the first notch 13.
In the present embodiment, the first notch 13 is provided with the upper end of body 1, the upper end of rotating cylinder 2 is provided with the second notch 25, rotating cylinder In 2 rotation processes, the second notch 25 can turn to the lower section of the first notch 13, you can is put into Chinese prescription or first dregs of a decoction and turns In cylinder 2.
Wherein, 1 upper end of body is provided with the feed inlet connected with the inner cavity 11, its lower end be provided with it is described interior The discharge port that chamber 11 connects.
In the present embodiment, the feed inlet connected with inner cavity 11 is set in 1 upper end of body, its lower end sets and connected with inner cavity 11 Discharge port, easy to which the first sugar wine solution of liquid or the second sugar wine solution are injected into cavity, and by cavity One soak or the second soak take out.
Wherein, in the step 4, squeezed the juice using dregs pressing device to second dregs of a decoction, as shown in Fig. 2, institute Stating dregs pressing device includes squeezing groove 4, material baffle 5, movable plate 6 and two servo electric cylinders 7 being oppositely arranged:
The squeezing groove 4 is vertically arranged, its inner hollow and upper and lower side is open is described to squeeze in groove 4 close to the position of its lower end Put it is horizontal removably be equipped with material baffle 5, be arranged at intervals with the material baffle 5 multiple confessions squeeze the juice through liquid-leaking nozzle 51;
The servo electric cylinders 7 are arranged on the lower section of movable plate 6, and its guide rod is vertically arranged, two servo electric cylinders 7 Guide rod be connected respectively with the movable plate 6, two guide rods drive the movable plates 6 to move up and down;
The movable plate 6 is arranged on 4 top of squeezing groove, and the lower section of movable plate 6 is provided with corresponding with the squeezing groove 4 Pressure head 61, the pressure head 61 are moved downward to the squeezing groove 4 and the groove with squeezing groove 4 under the driving of two servo electric cylinders 7 Bottom offsets, or is moved upward to the top of the squeezing groove 4.
Wherein, in the step 4, the juice obtained after being squeezed the juice using ceramic membrane filter device to second dregs of a decoction was carried out Filter.
Wherein, as shown in figure 3, the ceramic membrane filter device includes purpose ceramic-film filter 8 and pressue device 9, the pottery 8 top of porcelain film filter is equipped with feed inlet, and lower end is connected with discharge nozzle, and the pressue device 9 passes through hose and the ceramic membrane It is connected to and in communication with inside filter 8.
<Embodiment 2>
A kind of preparation method of Shennong medicinal liquor, comprises the following steps:
Step 1: by the berba aristolochiae mollissimae of 275 parts by weight, the Ligusticum wallichii of 275 parts by weight, the Radix Salviae Miltiorrhizae of 275 parts by weight, 275 parts by weight Windproof, 275 parts by weight costus root, the asiatic toddalia root-bark of 275 parts by weight, the caulis trachelospermi of 250 parts by weight, 200 parts by weight the bark of eucommia, The cortex acanthopanacis of 200 parts by weight, the geranium wilfordii of 200200 parts by weight, the sargentodoxa cuneata of 200 parts by weight, 200 parts by weight Sambucus chinensis, The caraway tea of 200 parts by weight, the giant knotweed of 200 parts by weight, the buckwheat pseudo-ginseng of 200 parts by weight, the Ciliatenerve Knotweed Root of 200 parts by weight, 200 weights Measure the tiger root and stem of certain plants of part, the Herba Polygoni Runcinati of 200 parts by weight, the radix bupleuri of 200 parts by weight, the Angelica sinensis of 125 parts by weight, the iron of 125 parts by weight Shoulder pole, the chrysanthemum pseudo-ginseng of 125 parts by weight, the playing both sides of the street of 125 parts by weight, the radix aconiti agrestis of 125 parts by weight, the blackberry lily of 125 parts by weight, 125 The wooden comb of parts by weight, the reticulate millettia of 125 parts by weight, the rhizoma atractylodis of 125 parts by weight, the Dysosma versipellis of 125 parts by weight, 125 parts by weight Cold water pellet, the root of Chinese clematis of 125 parts by weight, the lycopodium calvatum of 125 parts by weight, the levisticum of 55 parts by weight, 55 parts by weight climb rock it is fragrant, 55 The alangium of parts by weight, the paniculate swallowwort of 55 parts by weight, the uncaria of 55 parts by weight, 55 parts by weight calculate sub- root, 55 parts by weight Coniogramme japonica (Thunb.) Diels, the paris polyphylla of 55 parts by weight, the safflower of 55 parts by weight, the root of bidentate achyranthes difference of the pseudo-ginseng of 10 parts by weight and 10 parts by weight Crush, and be uniformly mixed after section or segment, obtain Chinese prescription, be placed in sterilizing cabinet after disinfection, it is spare;
Step 2: by the white wine in mass ratio 3 that sucrose and alcoholic strength are 55%:100 ratio mixing, it is molten to be made sugar wine Liquid, and by the sugar wine solution be added in step 1 sterilize after Chinese prescription in, it is closed immersion 18 days after, filtering, obtain First soak and first dregs of a decoction, it is spare;
Step 3: the white wine that alcoholic strength is 55% is added in first dregs of a decoction that step 2 obtains, closed immersion 18 days Afterwards, filter, obtain the second soak and second dregs of a decoction, it is spare;;
Step 4: second dregs of a decoction that step 3 is obtained are squeezed the juice and filtered, retain filtrate, and with first soak and Second soak is uniformly mixed, and is stood to clarifying, is taken supernatant liquor, that is, obtain the Shennong medicinal liquor;
Wherein, before the filtrate is uniformly mixed with first soak and the second soak, first described first is soaked Bubble liquid and the second soak are uniformly mixed, and are stood to clarification;In the step 2 and step 3, use is in the same manner as in Example 1 Medicinal liquor leaching device the Chinese prescription and first dregs of a decoction are soaked.
<Embodiment 3>
A kind of preparation method of Shennong medicinal liquor, comprises the following steps:
Step 1: by the berba aristolochiae mollissimae of 350 parts by weight, the Ligusticum wallichii of 350 parts by weight, the Radix Salviae Miltiorrhizae of 350 parts by weight, 350 parts by weight Windproof, 350 parts by weight costus root, the asiatic toddalia root-bark of 350 parts by weight, the caulis trachelospermi of 300 parts by weight, 300 parts by weight the bark of eucommia, The cortex acanthopanacis of 300 parts by weight, the geranium wilfordii of 300 parts by weight, the sargentodoxa cuneata of 300 parts by weight, the Sambucus chinensis of 300 parts by weight, 300 weights Measure the caraway tea of part, the giant knotweed of 300 parts by weight, the buckwheat pseudo-ginseng of 300 parts by weight, the Ciliatenerve Knotweed Root of 300 parts by weight, 3000 parts by weight The tiger root and stem of certain plants, the Herba Polygoni Runcinati of 300 parts by weight, the radix bupleuri of 300 parts by weight, the Angelica sinensis of 200 parts by weight, 200 parts by weight fringed iris herb, The chrysanthemum pseudo-ginseng of 200 parts by weight, the playing both sides of the street of 200 parts by weight, the radix aconiti agrestis of 200 parts by weight, the blackberry lily of 200 parts by weight, 200 parts by weight Wooden comb, the reticulate millettia of 200 parts by weight, the rhizoma atractylodis of 200 parts by weight, the Dysosma versipellis of 200 parts by weight, the cold water of 200 parts by weight it is red, The root of Chinese clematis of 200 parts by weight, the lycopodium calvatum of 200 parts by weight, the levisticum of 100 parts by weight, 100 parts by weight climb that rock is fragrant, 100 weight Part alangium, the paniculate swallowwort of 100 parts by weight, the uncaria of 10-100 parts by weight, 100 parts by weight calculate sub- root, 100 parts by weight Coniogramme japonica (Thunb.) Diels, the paris polyphylla of 100 parts by weight, the safflower of 100 parts by weight, the pseudo-ginseng of 20 parts by weight and the root of bidentate achyranthes of 20 parts by weight Crush, and be uniformly mixed after section or segment respectively, obtain Chinese prescription, be placed in sterilizing cabinet after disinfection, it is spare;
Step 2: by the white wine in mass ratio 10 that sucrose and alcoholic strength are 60%:100 ratio mixing, is made the first sugar Wine solution, and by the first sugar wine solution be added in step 1 sterilize after Chinese prescription in, it is closed immersion 620 days after, Filtering, obtains the first soak and first dregs of a decoction, spare;
Step 3: the white wine that alcoholic strength is 60% is added in first dregs of a decoction that step 2 obtains, closed immersion 20 days Afterwards, filter, obtain the second soak and second dregs of a decoction, it is spare;
Step 4: second dregs of a decoction that step 3 is obtained are squeezed the juice and filtered, retain filtrate, and with first soak and Second soak is uniformly mixed, and is stood to clarifying, is taken supernatant liquor, that is, obtain the Shennong medicinal liquor;
Wherein, before the filtrate is uniformly mixed with first soak and the second soak, first described first is soaked Bubble liquid and the second soak are uniformly mixed, and are stood to clarification;In the step 2 and step 3, using identical in embodiment 1 Medicinal liquor leaching device soaks the Chinese prescription and first dregs of a decoction.
<Comparative example 1>
A kind of preparation method of Shennong medicinal liquor, except in step 2 and step 3, using common vessel to the Chinese prescription Soaked with first dregs of a decoction, for remaining parameter with identical in embodiment 1, process is also identical.
<Comparative example 2>
A kind of preparation method of Shennong medicinal liquor, by the berba aristolochiae mollissimae of 275 parts by weight, the Ligusticum wallichii of 275 parts by weight, 275 parts by weight Radix Salviae Miltiorrhizae, windproof, 275 parts by weight the costus root of 275 parts by weight, the asiatic toddalia root-bark of 275 parts by weight, 250 parts by weight caulis trachelospermi, The bark of eucommia of 200 parts by weight, the cortex acanthopanacis of 200 parts by weight, the geranium wilfordii of 200 parts by weight, the sargentodoxa cuneata of 200 parts by weight, 200 weight Part Sambucus chinensis, the caraway tea of 200 parts by weight, the giant knotweed of 200 parts by weight, the buckwheat pseudo-ginseng of 200 parts by weight, 200 parts by weight Ciliatenerve Knotweed Root, the tiger root and stem of certain plants of 200 parts by weight, the Herba Polygoni Runcinati of 200 parts by weight, the radix bupleuri of 200 parts by weight, 125 parts by weight Angelica sinensis, The fringed iris herb of 125 parts by weight, the chrysanthemum pseudo-ginseng of 125 parts by weight, the playing both sides of the street of 125 parts by weight, the radix aconiti agrestis of 125 parts by weight, 125 weight Part blackberry lily, the wooden comb of 125 parts by weight, the reticulate millettia of 125 parts by weight, the rhizoma atractylodis of 125 parts by weight, 125 parts by weight Dysosma versipellis, The cold water pellet of 125 parts by weight, the root of Chinese clematis of 125 parts by weight, the lycopodium calvatum of 125 parts by weight, the levisticum of 55 parts by weight, 55 parts by weight Climb rock perfume, the alangium of 55 parts by weight, the paniculate swallowwort of 55 parts by weight, the uncaria of 55 parts by weight, 55 parts by weight calculate sub- root, The Coniogramme japonica (Thunb.) Diels of 55 parts by weight, the paris polyphylla of 55 parts by weight, the safflower of 55 parts by weight, the pseudo-ginseng of 10 parts by weight and 10 parts by weight The root of bidentate achyranthes smash or cut into slices respectively after, be uniformly mixed, be put into alcoholic strength be 50% white wine in soak 30 days, obtain legendary god of farming's medicine Wine.
<Test example 1>
At least specifically there are cervical spondylosis, scapulohumeral periarthritis, pain in waist and lower extremities, chronic strain and class wind at the selection age in 300 of 45-65 Sui Each 150 of a kind of patient in the osteoarthropathy such as wet arthritis, wherein men and women patient, with 30 female patients and 30 Male patient is one group, is divided into 5 groups, 60 days as a treatment course treat 2 courses for the treatment of, and wherein treatment group 1-3 takes the present invention respectively The Shennong medicinal liquor that comparative example 1 and 2 of the present invention obtains is taken respectively by the Shennong medicinal liquor that embodiment 1-3 is obtained, treatment group 4 and 5, treatment Situation is as follows;
Table 1:Treatment group's 1-5 treatment results
As shown in Table 1, the effect for the treatment of group 1-5 is respectively provided with expelling wind and clearing away cold, promoting blood circulation and removing blood stasis, relaxing tendons and activating collaterals, treatment group 1-3 effects Fruit is fairly obvious compared to 4 and 5 advantage for the treatment of group, and the average effectiveness level for the treatment of group 1-3 is 87.5%, and treatment group 4 and 5 is flat Efficient is 82.1%.And being averaged without recurrence rate in treatment group 1-3 is 16.4%, and the average nothing for the treatment of group 4 and 5 is answered Hair rate is 8.3%, and the active ingredient in Chinese medicine can be carried more to the preparation method of Shennong medicinal liquor provided by the invention Take out so that the Shennong medicinal liquor expelling wind and clearing away cold of preparation, it is promoting blood circulation and removing blood stasis, it is the effect of relaxing tendons and activating collaterals and better.
Although embodiment of the present invention is disclosed as above, it is not restricted in specification and embodiment listed With it can be applied to various suitable the field of the invention completely, can be easily for those skilled in the art Realize other modification, therefore under the universal limited without departing substantially from claim and equivalency range, it is of the invention and unlimited In specific details and shown here as the embodiment with description.

Claims (10)

1. a kind of preparation method of Shennong medicinal liquor, it is characterised in that comprise the following steps:
Step 1: by the berba aristolochiae mollissimae of 200-350 parts by weight, the Ligusticum wallichii of 200-350 parts by weight, 200-350 parts by weight Radix Salviae Miltiorrhizae, Windproof, 200-350 parts by weight the costus root of 200-350 parts by weight, the asiatic toddalia root-bark of 200-350 parts by weight, 200-300 parts by weight Caulis trachelospermi, the bark of eucommia of 100-300 parts by weight, the cortex acanthopanacis of 100-300 parts by weight, the geranium wilfordii of 100-300 parts by weight, 100- The sargentodoxa cuneata of 300 parts by weight, the Sambucus chinensis of 100-300 parts by weight, the caraway tea of 100-300 parts by weight, 100-300 parts by weight Giant knotweed, the buckwheat pseudo-ginseng of 100-300 parts by weight, the Ciliatenerve Knotweed Root of 100-300 parts by weight, the tiger root and stem of certain plants, the 100- of 100-300 parts by weight The Herba Polygoni Runcinati of 300 parts by weight, the radix bupleuri of 100-300 parts by weight, the Angelica sinensis of 50-200 parts by weight, the iron of 50-200 parts by weight are flat Load, the chrysanthemum pseudo-ginseng of 50-200 parts by weight, the playing both sides of the street of 50-200 parts by weight, the radix aconiti agrestis of 50-200 parts by weight, 50-200 parts by weight Blackberry lily, the wooden comb of 50-200 parts by weight, the reticulate millettia of 50-200 parts by weight, the rhizoma atractylodis of 50-200 parts by weight, 50-200 weight The Dysosma versipellis of part, cold water pellet, the root of Chinese clematis of 50-200 parts by weight, the lycopodium calvatum of 50-200 parts by weight, the 10- of 50-200 parts by weight The levisticums of 100 parts by weight, 10-100 parts by weight climb rock perfume, the alangium of 10-100 parts by weight, Xu's length of 10-100 parts by weight Minister in ancient times, the uncaria of 10-100 parts by weight, 10-100 parts by weight calculate sub- root, the Coniogramme japonica (Thunb.) Diels of 10-100 parts by weight, 10-100 weight Part paris polyphylla, the safflower of 10-100 parts by weight, the root of bidentate achyranthes of the pseudo-ginseng of 1-20 parts by weight and 1-20 parts by weight cut into slices respectively Or crushed after segment, and be uniformly mixed, Chinese prescription is obtained, is placed in sterilizing cabinet after disinfection, it is spare;
Step 2: the white wine 1-10 in mass ratio by sucrose with alcoholic strength for 50-60%:100 ratio mixing, it is molten to be made sugar wine Liquid, and by the sugar wine solution be added in step 1 sterilize after Chinese prescription in, it is closed immersion 15-20 days after, filter, obtain It is spare to the first soak and first dregs of a decoction;
Step 3: the white wine that alcoholic strength is 50-60% is added in first dregs of a decoction that step 2 obtains, closed immersion 15-20 After it, filtering, obtains the second soak and second dregs of a decoction, spare;
Step 4: second dregs of a decoction that step 3 is obtained are squeezed the juice and filtered, retain filtrate, and with first soak and second Soak is uniformly mixed, and is stood to clarifying, is taken supernatant liquor, that is, obtain the Shennong medicinal liquor.
2. a kind of preparation method of Shennong medicinal liquor as claimed in claim 1, it is characterised in that obtained in the step 1 described After Chinese prescription, after first the Chinese prescription is dispensed into multiple gauze bags, the gauze bag sack is tightened, then be placed on Disinfection in sterilizing cabinet.
3. a kind of preparation method of Shennong medicinal liquor as claimed in claim 1, it is characterised in that by the filter in the step 4 Before liquid is uniformly mixed with first soak and the second soak, first first soak and the second soak are mixed equal It is even, stand to clarification.
4. such as a kind of preparation method of Shennong medicinal liquor of claim 1-3 any one of them, it is characterised in that the step 2 and In step 3, the Chinese prescription and first dregs of a decoction are soaked using medicinal liquor leaching device, the medicinal liquor leaching device bag Include body (1), rotating cylinder (2) and shaft (3):
The body (1) has inner cavity (11);
The rotating cylinder (2) is the cylindrical shape of lower ending opening, it is vertically arranged in the inner cavity (11), outside the rotating cylinder (2) Multiple through holes (21) are arranged at intervals with side wall, multiple first raised (22), the inner cavity are arranged at intervals with its madial wall (11) bottom wall is equipped with toroidal cavity (12) corresponding with the rotating cylinder (2) lower end, and the lower end of the rotating cylinder (2) is rotatable Be arranged in the toroidal cavity (12), the upper end of the rotating cylinder (2) is coaxially arranged with a round bar (23), the round bar (23) upper end passes through the roof of the inner cavity (11) and extends to the body (1) outside, and the top of the body (1) is set There is the first motor (24), the output shaft of first motor (24) is connected with the upper end of the round bar (23), first motor (24) output shaft drives the round bar (23) and drives the rotating cylinder (2) to be rotated in the inner cavity (11);
The shaft (3) is vertically arranged in the inner cavity (11) and positioned at the rotating cylinder (2) inside, and is spaced on its lateral wall It is provided with multiple second raised (31), the lower end of the shaft (3) is pierced by the bottom wall of the inner cavity (11) and extends to described Body (1) is exterior, is provided with the second motor (32) below the body (1), the output shaft of second motor (32) with it is described The lower end connection of shaft (3), the output shaft of second motor (32) drive the shaft (3) to be rotated in the rotating cylinder (2), And the direction that the shaft (3) rotates is opposite with the direction that the rotating cylinder (2) rotates.
5. a kind of preparation method of Shennong medicinal liquor as claimed in claim 4, it is characterised in that be provided with the through hole (21) Prevent the filter screen that the dregs of a decoction pass through.
6. a kind of preparation method of Shennong medicinal liquor as claimed in claim 4, it is characterised in that open the upper end of the body (1) There is the first notch (13) passed through for Chinese medicine connected with the inner cavity (11), the upper end of the rotating cylinder (2) is provided with and described Corresponding the second notch (25) passed through for Chinese medicine of one notch (13), in rotating cylinder (2) rotation process, second notch (25) it can turn to below first notch (13).
7. a kind of preparation method of Shennong medicinal liquor as claimed in claim 4, it is characterised in that body (1) upper end is set There is the feed inlet connected with the inner cavity (11), its lower end is provided with the discharge port connected with the inner cavity (11).
8. such as a kind of preparation method of Shennong medicinal liquor of claim 1-3 any one of them, it is characterised in that the step 4 In, squeezed the juice using dregs pressing device to second dregs of a decoction, the dregs pressing device includes squeezing groove (4), material baffle (5), movable plate (6) and two servo electric cylinders (7) being oppositely arranged:
The squeezing groove (4) is vertically arranged, its inner hollow and upper and lower side is open, described to squeeze in groove (4) close to the position of its lower end Put it is horizontal removably be equipped with material baffle (5), be arranged at intervals with the material baffle (5) multiple confessions squeeze the juice through liquid-leaking nozzle (51);
The servo electric cylinders (7) are arranged on below the movable plate (6), and its guide rod is vertically arranged, two servo electric cylinders (7) guide rod is connected with the movable plate (6) respectively, and two guide rods drive the movable plate (6) to move up and down;
The movable plate (6) is arranged on above the squeezing groove (4), and it is right with the squeezing groove (4) to be provided with below the movable plate (6) The pressure head (61) answered, the pressure head (61) are moved downward to the squeezing groove (4) simultaneously under the driving of two servo electric cylinders (7) Slot bottom with squeezing groove (4) offsets, or is moved upward to the top of the squeezing groove (4).
9. such as a kind of preparation method of Shennong medicinal liquor of claim 1-3 any one of them, it is characterised in that the step 4 In, the juice obtained after being squeezed the juice using ceramic membrane filter device to second dregs of a decoction is filtered.
A kind of 10. preparation method of Shennong medicinal liquor as claimed in claim 9, it is characterised in that the ceramic membrane filter device Including purpose ceramic-film filter (8) and pressue device (9), purpose ceramic-film filter (8) top is equipped with feed inlet, and lower end is connected with Discharge nozzle, the pressue device (9) is by hose with being connected to and in communication with inside the purpose ceramic-film filter (8).
CN201711330343.4A 2017-12-13 2017-12-13 A kind of preparation method of Shennong medicinal liquor Pending CN108004100A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579936A (en) * 2012-03-06 2012-07-18 中国科学院武汉植物园 Shennong medicinal liquor and preparation method thereof
CN104591969A (en) * 2013-11-01 2015-05-06 宜昌万森生态科技发展有限公司 Natural borneol leaching device
CN104760315A (en) * 2015-04-22 2015-07-08 苏州神林堂中医药研究所 Chinese herbal medicine pressing device
CN105462793A (en) * 2016-01-29 2016-04-06 山东司邦得制药有限公司 Health-care medicinal liquor and preparation method thereof
WO2016078146A1 (en) * 2014-11-19 2016-05-26 胡桂香 Kidney-replenishing tincture
CN206372599U (en) * 2017-01-03 2017-08-04 石家庄市九洲兽药有限公司 A kind of ceramic membrane filter device
CN107286266A (en) * 2017-06-26 2017-10-24 浙江海洋大学 Extract the extraction equipment and its extracting method of red bayberry polysaccharide

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579936A (en) * 2012-03-06 2012-07-18 中国科学院武汉植物园 Shennong medicinal liquor and preparation method thereof
CN104591969A (en) * 2013-11-01 2015-05-06 宜昌万森生态科技发展有限公司 Natural borneol leaching device
WO2016078146A1 (en) * 2014-11-19 2016-05-26 胡桂香 Kidney-replenishing tincture
CN104760315A (en) * 2015-04-22 2015-07-08 苏州神林堂中医药研究所 Chinese herbal medicine pressing device
CN105462793A (en) * 2016-01-29 2016-04-06 山东司邦得制药有限公司 Health-care medicinal liquor and preparation method thereof
CN206372599U (en) * 2017-01-03 2017-08-04 石家庄市九洲兽药有限公司 A kind of ceramic membrane filter device
CN107286266A (en) * 2017-06-26 2017-10-24 浙江海洋大学 Extract the extraction equipment and its extracting method of red bayberry polysaccharide

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