CN107988165A - 具有改进特异性的修饰的t淋巴细胞 - Google Patents

具有改进特异性的修饰的t淋巴细胞 Download PDF

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Publication number
CN107988165A
CN107988165A CN201710991379.0A CN201710991379A CN107988165A CN 107988165 A CN107988165 A CN 107988165A CN 201710991379 A CN201710991379 A CN 201710991379A CN 107988165 A CN107988165 A CN 107988165A
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antigen
lymphocytes
modification
polypeptide
domain
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CN201710991379.0A
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Chinese (zh)
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毕涛·梁
斯图尔特·阿博特
伟·刘
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Celgene Corp
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Anthrogenesis Corp
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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CN201710991379.0A 2013-02-06 2014-02-06 具有改进特异性的修饰的t淋巴细胞 Pending CN107988165A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361761548P 2013-02-06 2013-02-06
US61/761,548 2013-02-06
CN201480020004.4A CN105101803A (zh) 2013-02-06 2014-02-06 具有改进特异性的修饰的t淋巴细胞

Related Parent Applications (1)

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CN201480020004.4A Division CN105101803A (zh) 2013-02-06 2014-02-06 具有改进特异性的修饰的t淋巴细胞

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CN107988165A true CN107988165A (zh) 2018-05-04

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CN201710991379.0A Pending CN107988165A (zh) 2013-02-06 2014-02-06 具有改进特异性的修饰的t淋巴细胞
CN201480020004.4A Pending CN105101803A (zh) 2013-02-06 2014-02-06 具有改进特异性的修饰的t淋巴细胞
CN202011174721.6A Pending CN113005091A (zh) 2013-02-06 2014-02-06 具有改进特异性的修饰的t淋巴细胞

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CN201480020004.4A Pending CN105101803A (zh) 2013-02-06 2014-02-06 具有改进特异性的修饰的t淋巴细胞
CN202011174721.6A Pending CN113005091A (zh) 2013-02-06 2014-02-06 具有改进特异性的修饰的t淋巴细胞

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US (2) US20150368360A1 (https=)
EP (3) EP3985028A1 (https=)
JP (3) JP6467661B2 (https=)
KR (2) KR102417657B1 (https=)
CN (3) CN107988165A (https=)
AU (3) AU2014214850C1 (https=)
CA (2) CA2904014C (https=)
ES (2) ES2898270T3 (https=)
HK (1) HK1254962A1 (https=)
NZ (2) NZ750426A (https=)
SG (2) SG11201507026WA (https=)
WO (1) WO2014124143A1 (https=)

Cited By (1)

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WO2024078485A1 (zh) * 2022-10-11 2024-04-18 四川大学华西医院 一种用于靶向肿瘤微环境的信号感受器和用于靶向治疗肿瘤的细胞

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SG11201507026WA (en) * 2013-02-06 2015-10-29 Anthrogenesis Corp Modified t lymphocytes having improved specificity
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KR20170037625A (ko) 2014-07-21 2017-04-04 노파르티스 아게 Cll-1 키메라 항원 수용체를 사용한 암의 치료
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