CN107982400A - A kind of coating medicine of burn and preparation method thereof - Google Patents
A kind of coating medicine of burn and preparation method thereof Download PDFInfo
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- CN107982400A CN107982400A CN201711387197.9A CN201711387197A CN107982400A CN 107982400 A CN107982400 A CN 107982400A CN 201711387197 A CN201711387197 A CN 201711387197A CN 107982400 A CN107982400 A CN 107982400A
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- 239000003814 drug Substances 0.000 title claims abstract description 101
- 239000011248 coating agent Substances 0.000 title claims abstract description 30
- 238000000576 coating method Methods 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims description 13
- 239000000843 powder Substances 0.000 claims abstract description 33
- 241000269420 Bufonidae Species 0.000 claims abstract description 28
- 241000239226 Scorpiones Species 0.000 claims abstract description 28
- 229920001800 Shellac Polymers 0.000 claims abstract description 28
- 239000004208 shellac Substances 0.000 claims abstract description 28
- 235000013874 shellac Nutrition 0.000 claims abstract description 28
- 229940113147 shellac Drugs 0.000 claims abstract description 28
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 claims abstract description 28
- 239000002435 venom Substances 0.000 claims abstract description 28
- 210000001048 venom Anatomy 0.000 claims abstract description 28
- 231100000611 venom Toxicity 0.000 claims abstract description 28
- 241000361919 Metaphire sieboldi Species 0.000 claims abstract description 22
- 239000000853 adhesive Substances 0.000 claims abstract description 21
- 230000001070 adhesive effect Effects 0.000 claims abstract description 21
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- 241000238631 Hexapoda Species 0.000 claims abstract description 20
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract description 20
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract description 20
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims abstract description 20
- 240000005373 Panax quinquefolius Species 0.000 claims abstract description 20
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 20
- 230000001954 sterilising effect Effects 0.000 claims abstract description 20
- 244000025254 Cannabis sativa Species 0.000 claims abstract description 18
- 241000397426 Centroberyx lineatus Species 0.000 claims abstract description 17
- QMGVPVSNSZLJIA-UHFFFAOYSA-N Nux Vomica Natural products C1C2C3C4N(C=5C6=CC=CC=5)C(=O)CC3OCC=C2CN2C1C46CC2 QMGVPVSNSZLJIA-UHFFFAOYSA-N 0.000 claims abstract description 9
- 244000107975 Strychnos nux-vomica Species 0.000 claims abstract description 9
- 238000002156 mixing Methods 0.000 claims description 48
- 239000011344 liquid material Substances 0.000 claims description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 239000008367 deionised water Substances 0.000 claims description 12
- 229910021641 deionized water Inorganic materials 0.000 claims description 12
- 238000000227 grinding Methods 0.000 claims description 12
- 239000004615 ingredient Substances 0.000 claims description 12
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 8
- 239000000571 coke Substances 0.000 claims description 6
- 230000000717 retained effect Effects 0.000 claims description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 241001116389 Aloe Species 0.000 claims description 5
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- CKQVRZJOMJRTOY-UHFFFAOYSA-N octadecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCCCCCCCC(O)=O CKQVRZJOMJRTOY-UHFFFAOYSA-N 0.000 claims description 5
- 239000003921 oil Substances 0.000 claims description 5
- 238000010792 warming Methods 0.000 claims description 5
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims description 4
- 239000010773 plant oil Substances 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 abstract description 6
- 239000002994 raw material Substances 0.000 abstract description 6
- 206010052428 Wound Diseases 0.000 abstract description 5
- 230000006378 damage Effects 0.000 abstract description 5
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- 241000894006 Bacteria Species 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
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- 206010053615 Thermal burn Diseases 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 230000035939 shock Effects 0.000 description 2
- 241000382455 Angelica sinensis Species 0.000 description 1
- 235000003717 Boswellia sacra Nutrition 0.000 description 1
- 240000007551 Boswellia serrata Species 0.000 description 1
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- 240000007311 Commiphora myrrha Species 0.000 description 1
- 235000006965 Commiphora myrrha Nutrition 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 244000247747 Coptis groenlandica Species 0.000 description 1
- 235000002991 Coptis groenlandica Nutrition 0.000 description 1
- 239000004863 Frankincense Substances 0.000 description 1
- 208000032456 Hemorrhagic Shock Diseases 0.000 description 1
- 235000007265 Myrrhis odorata Nutrition 0.000 description 1
- 241000283966 Pholidota <mammal> Species 0.000 description 1
- 240000004064 Poterium sanguisorba Species 0.000 description 1
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- 240000004980 Rheum officinale Species 0.000 description 1
- 235000008081 Rheum officinale Nutrition 0.000 description 1
- 235000008282 Sanguisorba officinalis Nutrition 0.000 description 1
- 206010049771 Shock haemorrhagic Diseases 0.000 description 1
- 241000157352 Uncaria Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000692 anti-sense effect Effects 0.000 description 1
- 238000009246 art therapy Methods 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
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- 230000036461 convulsion Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
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- 229940040145 liniment Drugs 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000036560 skin regeneration Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
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- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
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- A61K35/65—Amphibians, e.g. toads, frogs, salamanders or newts
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- Health & Medical Sciences (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Tropical Medicine & Parasitology (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
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- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to medical field, and in particular to a kind of coating medicine of burn, its component include:American Ginseng, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti earthworm, prepared nux vomica, courage grass, swallow tail, shellac, the dried venom of toads, toad-cortex, scorpion and adhesive;Medicine prepared by the present invention have the advantages that it is quick, anti-infective, cure it is different grades of burn and it is good to skin zero damage;Rhizoma Polygoni suffulti, earthworm, courage grass and prepared nux vomica are added in raw material and causes wound no inflammation, incrustation comes off fast;Shellac, the dried venom of toads, toad-cortex and scorpion are added in raw material causes speed of wound healing to be significantly improved, no infection;In addition prepared by the present invention is sterilized in the step e of medicine using high-pressure sterilizing pot so that the bacterium inside medicine kills, and prevents infected wound;Curative effect of the present invention is good, mitigates the wounded's economic expenditure.
Description
Technical field
The present invention relates to medical field, and in particular to coating medicine of a kind of burn and preparation method thereof.
Background technology
Burn is a kind of body injury caused by heating power, mainly injures skin or mucous membrane, and severe patient can also injure skin
Lower or/and sub-mucosal tissues.Impaired skin histology easily causes to infect by exposure to external environment condition, or even festers,
Wound long-time disunion, or cure the problems such as leaving scar afterwards.The method and medicine treated at present are very much, skin of performing the operation
Transplanting, pain is big, and some repeatedly can just take effect;The general slowly effect of drug therapy, and easy infection.
Such as Chinese Patent Application No. is a kind of burn cream of CN201610584635.X and preparation method thereof.The burn cream bag
Include the raw material components of following parts by weight:30 80 parts of radix scutellariae, 30 80 parts of the coptis, 30 80 parts of garden burnet, 30 80 parts of rheum officinale, uncaria
30 80 parts, 30 80 parts of Angelica sinensis, 30 80 parts of pangolin, 30 80 parts of frankincense, 30 80 parts of myrrh, 2,000 6000 parts of siritch,
400 1200 parts of beeswax.Burn cream provided by the invention have it is clearing heat and detoxicating, by wet apocenosis, it is promoting blood circulation and removing blood stasis, remove necrosis and promote granulation, subside a swelling
Analgesic, wind-dispelling is relieving convulsion, grows the advantages of U.S. skin, for deep II degree and III degree of burn and scald without surgery skin grafting, without biological skill
Art and immunotherapy, can reach the purpose of antibacterial anti-inflammatory, Hemorrhagic shock, do not stay scar and healing time is short.
The quality of the coating medicine of currently marketed burn still has much room for improvement, such as the liniment of currently marketed burn
Thing does not only exist the shortcomings that slowly effect and easy infection, and also presence cannot cure different grades of burn and have damage etc. to lack skin
Point, the use scope of the coating medicine of this currently marketed burn also made compare limitation.
The content of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of coating medicine of burn, not only with quick and
Not easy infection, also has the advantages that to cure different grades of burn and to skin zero damage.
In order to achieve the above object, the present invention is achieved by the following technical programs:
A kind of coating medicine of burn, its component is by weight:15-22 parts of American Ginseng, 8-12 parts of Resina Draconis, pearl powder 6-
10 parts, 10-15 parts of lotus leaf, 12-16 parts of honeysuckle, 3-6 parts of insect wax, 2-5 parts of Rhizoma Polygoni suffulti, 2.5-3.8 parts of earthworm, prepared nux vomica
5.5-7.5 parts, 6.5-9.5 parts of courage grass, 1.8-3.5 parts of swallow tail, 1.8-2.9 parts of shellac, 0.5-1.2 parts of the dried venom of toads, toad-cortex
8-11 parts of 1.2-1.8 parts, 0.9-1.6 parts of scorpion and adhesive.
Preferably, the preparation method of the coating medicine of a kind of burn, comprises the following steps:
A, respectively by American Ginseng, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass, swallow tail,
Shellac, the dried venom of toads, toad-cortex and scorpion clean dry are placed in Chinese medicine ultra micro grinding mill and mill, then by 80 mesh sieves,
Gained each component powder is retained separately, spare;
B, by the American Ginseng obtained by step a, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, vomiting nut
Powder, courage grass and swallow tail fat are added in Chinese medicine decoction machine, and 15-20 times of deionized water is added into Chinese medicine decoction machine, heating
To 60-80 DEG C, 35-45min is then cooked by slow fire, gained medicament is medicament A;
C, medicament A is added in liquid material a mixing bowl, then adds adhesive, shellac, the dried venom of toads, toad-cortex, scorpion, side thereto
Stirring side adds shellac, the dried venom of toads, toad-cortex and the scorpion powder obtained by step a thereto, then adds 3-5 times of deionized water
Enter wherein and will be vacuumized in liquid material a mixing bowl, the temperature in liquid material a mixing bowl is 80-95 DEG C, mixing time 5-10min, institute
Obtain component and be denoted as blending ingredients B;
D, the blending ingredients B in step c is placed in Chinese medicine decoction machine, temperature is 85-95 DEG C, is decocted to surface as in buff
Portion is coke yellow, and room temperature cools down, and gained medicament is bottled;
E, gained bottling medicament in step d is placed in high-pressure sterilizing pot and carries out autoclaving, sterilization time 40-50min, finally
Obtain burn coating medicine.
Preferably, described adhesive selects vegetable oil, aloe, Dormant oils, stearyl alcohol and three kinds therein of stearine
Or four kinds.
Preferably, the temperature in the Chinese medicine ultra micro grinding mill in the step a is 50-80 DEG C.
Preferably, the mixing speed of the liquid material a mixing bowl in the step c is 300-380r/min.
Preferably, pressure is 200-280MPa in the high-pressure sterilizing pot in the step e.
Beneficial effect:
The present invention with American Ginseng, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass, swallow tail,
Shellac, the dried venom of toads, toad-cortex, scorpion and adhesive have quick, anti-sense as the raw material for preparing coating, prepared medicine
Contaminate, cure it is different grades of burn and to skin zero damage it is good the advantages that.In raw material add Rhizoma Polygoni suffulti, earthworm, courage grass and
Prepared nux vomica causes wound no inflammation, and incrustation comes off fast;Shellac, the dried venom of toads, toad-cortex and scorpion is added in raw material to hinder
Mouth healing rate is significantly improved, no infection.In addition prepared by the present invention is gone out in the step e of medicine using high-pressure sterilizing pot
Bacterium so that the bacterium inside medicine kills, and prevents infected wound.It is substantially material common on the market that adhesive, which is selected, is made
Cost of manufacture is obtained to decline.Curative effect of the present invention is good, mitigates the wounded's economic expenditure.
Embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention,
Technical solution in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is the present invention one
Divide embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not making
All other embodiments obtained under the premise of creative work, belong to the scope of protection of the invention.
Embodiment 1:
A kind of coating medicine of burn, its component is by weight:15 parts of American Ginseng, 12 parts of Resina Draconis, 6 parts of pearl powder, lotus
10 parts of leaf, 12 parts of honeysuckle, 3 parts of insect wax, 2 parts of Rhizoma Polygoni suffulti, 2.5 parts of earthworm, 5.5 parts of prepared nux vomica, courage careless 9.5 parts, swallow
8 parts of 1.8 parts of tail, 2.9 parts of shellac, 0.5 part of the dried venom of toads, 1.2 parts of toad-cortex, 0.9 part of scorpion and adhesive.
A kind of preparation method of the coating medicine of burn, comprises the following steps:
A, respectively by American Ginseng, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass, swallow tail,
Shellac, the dried venom of toads, toad-cortex and scorpion clean dry are placed in Chinese medicine ultra micro grinding mill and mill, then by 80 mesh sieves,
Gained each component powder is retained separately, spare;
B, by the American Ginseng obtained by step a, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass and
Swallow tail fat is added in Chinese medicine decoction machine, and 15 times of deionized water is added into Chinese medicine decoction machine, is warming up to 60 DEG C, Ran Houwen
Fire decocts 35min, and gained medicament is medicament A;
C, medicament A is added in liquid material a mixing bowl, then adds adhesive, shellac, the dried venom of toads, toad-cortex, scorpion, side thereto
Stirring side adds shellac, the dried venom of toads, toad-cortex and the scorpion powder obtained by step a thereto, then adds 5 times of deionized water
It will vacuumize wherein and in liquid material a mixing bowl, the temperature in liquid material a mixing bowl is 80 DEG C, mixing time 5min, obtained component note
For blending ingredients B;
D, the blending ingredients B in step c is placed in Chinese medicine decoction machine, temperature is 85 DEG C, is decocted to surface as inside buff
For coke yellow, room temperature cooling, gained medicament is bottled;
E, gained bottling medicament in step d is placed in high-pressure sterilizing pot and carries out autoclaving, sterilization time 50min, is finally obtained
Must be burnt coating medicine.
Adhesive selects vegetable oil, aloe and Dormant oils.
The temperature in Chinese medicine ultra micro grinding mill in step a is 50 DEG C.
The mixing speed of liquid material a mixing bowl in step c is 300r/min.
Pressure is 200MPa in high-pressure sterilizing pot in step e.
Embodiment 2:
A kind of coating medicine of burn, its component is by weight:17 parts of American Ginseng, 8 parts of Resina Draconis, 7 parts of pearl powder, lotus leaf
15 parts, 13 parts of honeysuckle, 4 parts of insect wax, 3 parts of Rhizoma Polygoni suffulti, 3.2 parts of earthworm, 6.5 parts of prepared nux vomica, courage careless 7.5 parts, swallow tail
10 parts of 2.4 parts, 1.8 parts of shellac, 0.7 part of the dried venom of toads, 1.6 parts of toad-cortex, 1.2 parts of scorpion and adhesive.
A kind of preparation method of the coating medicine of burn, comprises the following steps:
A, respectively by American Ginseng, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass, swallow tail,
Shellac, the dried venom of toads, toad-cortex and scorpion clean dry are placed in Chinese medicine ultra micro grinding mill and mill, then by 80 mesh sieves,
Gained each component powder is retained separately, spare;
B, by the American Ginseng obtained by step a, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass and
Swallow tail fat is added in Chinese medicine decoction machine, and 17 times of deionized water is added into Chinese medicine decoction machine, is warming up to 65 DEG C, Ran Houwen
Fire decocts 38min, and gained medicament is medicament A;
C, medicament A is added in liquid material a mixing bowl, then adds adhesive, shellac, the dried venom of toads, toad-cortex, scorpion, side thereto
Stirring side adds shellac, the dried venom of toads, toad-cortex and the scorpion powder obtained by step a thereto, then adds 3.8 times of deionized water
Enter wherein and will be vacuumized in liquid material a mixing bowl, the temperature in liquid material a mixing bowl is 90 DEG C, mixing time 7min, obtained component
It is denoted as blending ingredients B;
D, the blending ingredients B in step c is placed in Chinese medicine decoction machine, temperature is 92 DEG C, is decocted to surface as inside buff
For coke yellow, room temperature cooling, gained medicament is bottled;
E, gained bottling medicament in step d is placed in high-pressure sterilizing pot and carries out autoclaving, sterilization time 40min, is finally obtained
Must be burnt coating medicine.
Adhesive selects vegetable oil, Dormant oils and stearine.
The temperature in Chinese medicine ultra micro grinding mill in step a is 70 DEG C.
The mixing speed of liquid material a mixing bowl in step c is 360r/min.
Pressure is 260MPa in high-pressure sterilizing pot in step e.
Embodiment 3:
A kind of coating medicine of burn, its component is by weight:19 parts of American Ginseng, 10 parts of Resina Draconis, 9 parts of pearl powder, lotus
13 parts of leaf, 14 parts of honeysuckle, 6 parts of insect wax, 4 parts of Rhizoma Polygoni suffulti, 3.2 parts of earthworm, 6.5 parts of prepared nux vomica, courage careless 6.5 parts, swallow
11 parts of 2.9 parts of tail, 2.6 parts of shellac, 1 part of the dried venom of toads, 1.4 parts of toad-cortex, 1.4 parts of scorpion and adhesive.
A kind of preparation method of the coating medicine of burn, comprises the following steps:
A, respectively by American Ginseng, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass, swallow tail,
Shellac, the dried venom of toads, toad-cortex and scorpion clean dry are placed in Chinese medicine ultra micro grinding mill and mill, then by 80 mesh sieves,
Gained each component powder is retained separately, spare;
B, by the American Ginseng obtained by step a, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass and
Swallow tail fat is added in Chinese medicine decoction machine, and 19 times of deionized water is added into Chinese medicine decoction machine, is warming up to 70 DEG C, Ran Houwen
Fire decocts 42min, and gained medicament is medicament A;
C, medicament A is added in liquid material a mixing bowl, then adds adhesive, shellac, the dried venom of toads, toad-cortex, scorpion, side thereto
Stirring side adds shellac, the dried venom of toads, toad-cortex and the scorpion powder obtained by step a thereto, then adds 3.8 times of deionized water
Enter wherein and will be vacuumized in liquid material a mixing bowl, the temperature in liquid material a mixing bowl is 90 DEG C, mixing time 7min, obtained component
It is denoted as blending ingredients B;
D, the blending ingredients B in step c is placed in Chinese medicine decoction machine, temperature is 92 DEG C, is decocted to surface as inside buff
For coke yellow, room temperature cooling, gained medicament is bottled;
E, gained bottling medicament in step d is placed in high-pressure sterilizing pot and carries out autoclaving, sterilization time 40min, is finally obtained
Must be burnt coating medicine.
Adhesive selects vegetable oil, aloe, stearyl alcohol and three kinds or four kinds therein of stearine.
The temperature in Chinese medicine ultra micro grinding mill in step a is 70 DEG C.
The mixing speed of liquid material a mixing bowl in step c is 380r/min.
Pressure is 220MPa in high-pressure sterilizing pot in step e.
Embodiment 4:
A kind of coating medicine of burn, its component is by weight:22 parts of American Ginseng, 9 parts of Resina Draconis, 10 parts of pearl powder, lotus
12 parts of leaf, 16 parts of honeysuckle, 5 parts of insect wax, 5 parts of Rhizoma Polygoni suffulti, 3.8 parts of earthworm, 7.5 parts of prepared nux vomica, courage careless 8.5 parts, swallow
9 parts of 3.5 parts of tail, 2.2 parts of shellac, 1.2 parts of the dried venom of toads, 1.8 parts of toad-cortex, 1.6 parts of scorpion and adhesive.
A kind of preparation method of the coating medicine of burn, comprises the following steps:
A, respectively by American Ginseng, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass, swallow tail,
Shellac, the dried venom of toads, toad-cortex and scorpion clean dry are placed in Chinese medicine ultra micro grinding mill and mill, then by 80 mesh sieves,
Gained each component powder is retained separately, spare;
B, by the American Ginseng obtained by step a, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass and
Swallow tail fat is added in Chinese medicine decoction machine, and 20 times of deionized water is added into Chinese medicine decoction machine, is warming up to 80 DEG C, Ran Houwen
Fire decocts 45min, and gained medicament is medicament A;
C, medicament A is added in liquid material a mixing bowl, then adds adhesive, shellac, the dried venom of toads, toad-cortex, scorpion, side thereto
Stirring side adds shellac, the dried venom of toads, toad-cortex and the scorpion powder obtained by step a thereto, then adds 3 times of deionized water
It will vacuumize wherein and in liquid material a mixing bowl, the temperature in liquid material a mixing bowl is 95 DEG C, mixing time 10min, obtained component
It is denoted as blending ingredients B;
D, the blending ingredients B in step c is placed in Chinese medicine decoction machine, temperature is 95 DEG C, is decocted to surface as inside buff
For coke yellow, room temperature cooling, gained medicament is bottled;
E, gained bottling medicament in step d is placed in high-pressure sterilizing pot and carries out autoclaving, sterilization time 46min, is finally obtained
Must be burnt coating medicine.
Adhesive selects aloe, Dormant oils, stearyl alcohol and three kinds or four kinds therein of stearine.
The temperature in Chinese medicine ultra micro grinding mill in step a is 80 DEG C.
The mixing speed of liquid material a mixing bowl in step c is 330r/min.
Pressure is 280MPa in high-pressure sterilizing pot in step e.
Application example:
Example 1:Mr. Wang, hot water scald, severe pain, which causes, to lose one's temper, and mismatches treatment, or even painful shock occurs, and makes
With 3min pain reliefs after this medicine, 10-20min pains stop, can quiet down and receive further treatment, while without pain again
Property shock occur.
Example 2:Jiang, deep burn patient, using after this medicine, can be effectively promoted skin regeneration, make III without skin not rawhide
Degree burn and II degree burn need not make skin graft and can fully recover.
Example 3:Platform, shallow II degree burn patient, using after this medicine, fully recovers for 8-12 days.
Example 4:Sun, deep ii degree burn patient, using after this medicine, fully recovers for 20 days or so.
Example 5:Zhao, III degree burn patients, using after this medicine, fully recover for 48 days or so.
Clinical trial results are substantially identical with application example.
It should be noted that herein, relational terms such as first and second and the like are used merely to a reality
Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation
In any this actual relation or order.Moreover, term " comprising ", "comprising" or its any other variant are intended to
Non-exclusive inclusion, so that process, method, article or equipment including a series of elements not only will including those
Element, but also including other elements that are not explicitly listed, or further include as this process, method, article or equipment
Intrinsic key element.In the absence of more restrictions, the key element limited by sentence "including a ...", it is not excluded that
Also there are other identical element in process, method, article or equipment including the key element.
The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations;Although with reference to the foregoing embodiments
The present invention is described in detail, it will be understood by those of ordinary skill in the art that:It still can be to foregoing each implementation
Technical solution described in example is modified, or carries out equivalent substitution to which part technical characteristic;And these modification or
Replace, the essence of appropriate technical solution is departed from the spirit and scope of various embodiments of the present invention technical solution.
Claims (6)
1. the coating medicine of a kind of burn, it is characterised in that its component is by weight:15-22 parts of American Ginseng, Resina Draconis 8-
12 parts, 6-10 parts of pearl powder, 10-15 parts of lotus leaf, 12-16 parts of honeysuckle, 3-6 parts of insect wax, 2-5 parts of Rhizoma Polygoni suffulti, earthworm 2.5-
3.8 parts, 5.5-7.5 parts of prepared nux vomica, 6.5-9.5 parts of courage grass, 1.8-3.5 parts of swallow tail, 1.8-2.9 parts of shellac, the dried venom of toads
8-11 parts of 0.5-1.2 parts, 1.2-1.8 parts of toad-cortex, 0.9-1.6 parts of scorpion and adhesive.
2. the preparation method of the coating medicine of a kind of burn according to claim 1, it is characterised in that including following step
Suddenly:
A, respectively by American Ginseng, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass, swallow tail,
Shellac, the dried venom of toads, toad-cortex and scorpion clean dry are placed in Chinese medicine ultra micro grinding mill and mill, then by 80 mesh sieves,
Gained each component powder is retained separately, spare;
B, by the American Ginseng obtained by step a, Resina Draconis, pearl powder, lotus leaf, honeysuckle, insect wax, Rhizoma Polygoni suffulti, earthworm, courage grass and
Swallow tail fat is added in Chinese medicine decoction machine, and 15-20 times of deionized water is added into Chinese medicine decoction machine, is warming up to 60-80 DEG C,
Then 35-45min is cooked by slow fire, gained medicament is medicament A;
C, medicament A is added in liquid material a mixing bowl, then adds adhesive, shellac, the dried venom of toads, toad-cortex, scorpion, side thereto
Stirring side adds shellac, the dried venom of toads, toad-cortex and the scorpion powder obtained by step a thereto, then adds 3-5 times of deionized water
Enter wherein and will be vacuumized in liquid material a mixing bowl, the temperature in liquid material a mixing bowl is 80-95 DEG C, mixing time 5-10min, institute
Obtain component and be denoted as blending ingredients B;
D, the blending ingredients B in step c is placed in Chinese medicine decoction machine, temperature is 85-95 DEG C, is decocted to surface as in buff
Portion is coke yellow, and room temperature cools down, and gained medicament is bottled;
E, gained bottling medicament in step d is placed in high-pressure sterilizing pot and carries out autoclaving, sterilization time 40-50min, finally
Obtain burn coating medicine.
A kind of 3. coating medicine of burn according to claim 1, it is characterised in that:Described adhesive selects plant
Oil, aloe, Dormant oils, stearyl alcohol and three kinds or four kinds therein of stearine.
A kind of 4. preparation method of the coating medicine of burn according to claim 2, it is characterised in that:The step a
In Chinese medicine ultra micro grinding mill in temperature be 50-80 DEG C.
A kind of 5. preparation method of the coating medicine of burn according to claim 2, it is characterised in that:The step c
In the mixing speed of liquid material a mixing bowl be 300-380r/min.
A kind of 6. preparation method of the coating medicine of burn according to claim 2, it is characterised in that:The step e
In high-pressure sterilizing pot in pressure be 200-280MPa.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108635513A (en) * | 2018-08-08 | 2018-10-12 | 李琴 | A kind of drug that treating burn and scald, preparation method and application |
WO2022146671A1 (en) * | 2020-12-31 | 2022-07-07 | Benjamin Moore & Co. | High pressure-processed architectural coating compositions and methods for high pressure-processing of architectural coating compositions |
CN115998821A (en) * | 2022-12-30 | 2023-04-25 | 成都市双流区中医医院 | Headache treating bolus and its prepn |
-
2017
- 2017-12-20 CN CN201711387197.9A patent/CN107982400A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108635513A (en) * | 2018-08-08 | 2018-10-12 | 李琴 | A kind of drug that treating burn and scald, preparation method and application |
WO2022146671A1 (en) * | 2020-12-31 | 2022-07-07 | Benjamin Moore & Co. | High pressure-processed architectural coating compositions and methods for high pressure-processing of architectural coating compositions |
CN115998821A (en) * | 2022-12-30 | 2023-04-25 | 成都市双流区中医医院 | Headache treating bolus and its prepn |
CN115998821B (en) * | 2022-12-30 | 2024-03-26 | 成都市双流区中医医院 | Headache treating bolus and its prepn |
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