CN107976794A - A kind of variable mating plate thickness and the mating plate of length illuminate microscopical lighting system - Google Patents
A kind of variable mating plate thickness and the mating plate of length illuminate microscopical lighting system Download PDFInfo
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- CN107976794A CN107976794A CN201810031689.2A CN201810031689A CN107976794A CN 107976794 A CN107976794 A CN 107976794A CN 201810031689 A CN201810031689 A CN 201810031689A CN 107976794 A CN107976794 A CN 107976794A
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/09—Beam shaping, e.g. changing the cross-sectional area, not otherwise provided for
- G02B27/0938—Using specific optical elements
- G02B27/095—Refractive optical elements
- G02B27/0955—Lenses
- G02B27/0966—Cylindrical lenses
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Abstract
The invention belongs to micro-imaging technique field, and in particular to a kind of mating plate illuminates microscope illumination light path；A kind of variable mating plate thickness and the mating plate illumination microscope illumination light path system of length are provided：Included successively by thing side to image side along optical axis arrangement：Laser light source, four constituent element mechanical compensations of full spherical mirror are without burnt zoom beam-expanding system, cylindrical lens, microcobjective；The light sent from laser light source, by the change that outgoing laser beams bore is realized without burnt zoom beam-expanding system, again a kind of piece light is formed by the cylindrical lens that rotation axis is rotated by 90 ° of optical axis by one, the piece light formed goes abatement due to the spherical aberration produced without burnt zoom beam-expanding system and cylindrical lens by an aplanasia microcobjective again, and the light intensity of whole mating plate can be made more uniform, the observation to the biological specimen in the range of certain size can be realized in the case where being changed without mating plate lighting system.
Description
Technical field
The invention belongs to micro-imaging technique field, and in particular to a kind of mating plate illuminates microscope illumination light path.
Background technology
Mating plate illumination microscope is a kind of new light microscope.It is different from traditional fluorescence microscope, mating plate illumination
Microscopical illumination path is mutually perpendicular to fluorescence detection light path.Illuminating bundle forms within the specific limits by cylindrical lens
Very thin thickness, well-proportioned sheet beam, and detect light path and detection imaging, exciting light are carried out in the direction vertical with illumination path
Beam is limited near detection object lens focal plane.The phototoxicity of mating plate illumination microscope imaging is weak, and image taking speed is fast, is adapted for living
Body tissue three-dimensional is imaged and long-time real time imagery, can obtain the real-time dynamic of cell and subcellsular level.Therefore, mating plate shines
Obvious micro mirror has very important meaning for life science.
The microscopical layer of mating plate illumination is cut ability and is mainly determined by mating plate thickness, and its visual field is exactly the length of whole mating plate
Degree.3D figure such as the attached drawings 1 of mating plate show that it is Rayleigh that its thickness, which is defined as laser by the size (w) with a tight waist after illumination objective lens, visual field,
Distance (L), clear aperture are defined as mating plate height (h).Observe various sizes of sample, it is desirable to mating plate thickness and length also have
Institute is different.What the microscopical mating plate thickness of existing most of mating plate and length were to determine, so to different size samples
This observation just needs replacing different types of mating plate microscope, and this greatly limits mating plate to illuminate microscopical use scope.
Since the shape of mating plate is related with the laser beam bore for inciding cylindrical mirror, this patent proposes a kind of nothing based on full spherical mirror
The design of burnt zoom beam-expanding system is to obtain the new method of the mating plate of thickness and length consecutive variations so that is illuminated in a mating plate
Accomplish the observation to different size samples in a certain range on microscope.
2011G.Ritter et al.[1]Devise a full cylindrical mirror without burnt zoom beam-expanding system, it expands ratio
For 6.3, and it is applied in mating plate illumination microscope, realizes the observation to different size samples.But due to its full column
It is smaller that what face mirror system was realized expand, and the different size ranges of the sample that can be observed are also smaller；And due to whole system
For full cylindrical mirror, processing and adjustment are all especially difficult, and manufacture and assembly cost are very high.
[1]G,Ritter,Jan-Hendrik,Spille,Tim,Kaminski,and,Ulrich,
Kubitscheck*.A cylindrical zoom lens unit for adjustable optical sectioning
in light sheet microscopy[J].OSA,2010,2(138857):185-193。
Changchun University of Science and Technology Liu Huan in 2010 is precious, An Zhiyong et al. have developed a expand than the three-component zooming for 2-12
Beam-expanding system, is mainly used in laser radar and laser range finder[2].Laser is expanded although also achieving, due to
The overall length of the system changes with expanding than change, it is impossible to applied in mating plate fluorescent illumination microscope.
[2] Liu Huanbao, peace will is brave, and high Yu contains, and Xiao makees a kind of river Design for Laser Expanding Optical System with Variable Focus [J] Changchun reason
Work college journal (natural science edition), 2010,33 (04):43-45.
The content of the invention
The object of the present invention is to provide a kind of variable mating plate thickness and the mating plate of length to illuminate microscope illumination light path system,
In the case where being changed without mating plate lighting system, the observation to the biological specimen in the range of certain size is realized.
To achieve the above object of the invention, the technical scheme is that：
A kind of variable mating plate thickness and the mating plate of length illuminate microscopical lighting system, are included successively by thing side to image side
Along optical axis arrangement：Laser light source, without burnt zoom beam-expanding system, cylindrical lens, microcobjective, wherein described expand without burnt zoom
Beam system for full spherical mirror four constituent element mechanical compensations without burnt zoom beam-expanding system, the four constituent element mechanical compensations are without burnt zoom
Beam-expanding system fixes group, zoom group, compensation group and fixes group afterwards before being followed successively by from thing side to image side, Jiao of the preceding fixed group
Away from for just, the focal length of zoom group be bear, the focal length of compensation group be bear, the focal length of fixed group is just afterwards；Sent out from the laser light source
The light gone out is used to the collimated light beam being modulated to column by first fixed group without burnt zoom beam-expanding system, the cylindrical lens
After being imaged at the front focus of fixed group, the light from rear fixed group outgoing is collimated light beam, is passed through for surface wave, zoom group and compensation group
It is compressed in by the cylindrical lens that rotation axis is rotated by 90 ° of optical axis at postposition microcobjective front focus, finally by the micro- thing of aplanasia
Mirror eliminates the spherical aberration introduced without burnt zoom beam-expanding system and cylindrical lens, obtains required mating plate.
Above-mentioned four constituent elements mechanical compensation is without burnt zoom beam-expanding system, and the distance between fixed group and rear fixed group are kept before it
It is constant, realize the overall length of whole lighting system not with expand than change and the technique effect that changes.Such lighting system
Overall length is fixed, and can simplify the Machine Design of system, convenient for users to the observation to sample.
Above-mentioned four constituent elements mechanical compensation without burnt zoom beam-expanding system, first fixed group, zoom group, compensation group and rear fixed group
Focal length is followed successively by " positive and negative, negative, positive ".Can realize shorter system overall length in the case of system visual field is less, be conducive to be
The miniaturization of system；This setting, realizes：System overall length is fixed；System overall length is shorter；Avoid higher laser energy damage mirror
The technique effect of piece.
What the aplanasia microcobjective was brought has the technical effect that：Both eliminated without burnt zoom beam-expanding system and cylindrical lens
The spherical aberration of introducing, reduces design and difficulty of processing without burnt zoom beam-expanding system and cylindrical lens, and makes the light intensity of mating plate more
Uniformly.
Preferably：Above-mentioned four constituent elements mechanical compensation is without burnt zoom beam-expanding system, system stop laser before first fixed group
The place with a tight waist of light source, this setting can fix stop position and size, greatly reduce the difficulty of Machine Design, and make system
Total light energy is constant.
Preferably：First fixed group is made of an one negative, positive two panels simple lens, and zoom group is a monolithic negative lens, compensation group
It is that two panels bears simple lens, rear fixed group is two panels positive single lens.That brings has the technical effect that：Preceding fixed group for it is one negative, one just two
Piece simple lens, first piece of negative lens cause less laser beam to increase, avoid laser and be focused into smaller focus on eyeglass,
Eyeglass is damaged, rear a piece of positive lens compression light drift angle causes whole system bore to be unlikely to excessive.Zoom group is selected single negative
Lens so that whole system structure is compacter.Compensation group uses two panels to bear simple lens make it that whole compensation group focal power is negative
While so that focal power distribution is more uniform, avoids drift angle larger on single refraction sphere.Fixation is organized as two panels just afterwards
Simple lens, while fixed group focal power is positive after guarantee is whole, mutually compensates for the spherical aberration of the two panels negative lens of compensation group, subtracts
Small system aberration.
The incident light that laser light source is sent in above-mentioned technical proposal shoot laser beam mouth after without burnt zoom beam-expanding system
Footpath is 1-10mm.Shoot laser beam bore has the technical effect that for what 1-10mm was brought：It is emitted after without burnt zoom beam-expanding system
Laser beam is most absolutely between twenties microns, can be adapted for observation in several microns by the mating plate thickness that cylindrical lens are adjusted to
Several animal and plant cells and embryo's sample；In addition shoot laser beam bore is 1-10mm after without burnt zoom beam-expanding system, also
Can guarantee that mating plate width and light intensity in rational scope：If shoot laser beam bore is too small, obtained mating plate width is small, can
Sample range for observation also diminishes, if shoot laser beam bore is excessive, can increase the size of rear end cylindrical lens, and meeting
Reduce the light intensity in mating plate width range.
The zoom ratio of no burnt zoom beam-expanding system is 10 times.That brings has the technical effect that：10 times are selected to expand without burnt zoom
Beam system both can obtain required mating plate thickness and length in the case where being not required multistage to expand, and reduce whole system
Design difficulty.In addition, 10 times of beam-expanding systems also cause the rear part lens hole footpath of system to be unlikely to excessive, and increase processing and
The difficulty of adjustment.
Preferable cylindrical lens are plano-convex cylindrical lens in above-mentioned technical proposal.The incident light that laser light source is sent passes through to be become without Jiao
After times beam-expanding system then vertical incidence modulates light in blocks, the skill brought to plano-convex cylindrical lens by the pillar face of plano-convex cylindrical lens
Art effect is：1st, circular light spot is compressed into wire hot spot；2nd, system spherical aberration is reduced；3rd, plano-convex cylindrical lens compared to biconvex or
The adjustment easy to process of person's concave-concave cylindrical lens.
In specific above-mentioned technical proposal：The image-side numerical aperture NA=0.25 of aplanasia microcobjective, back work distance from
More than or equal to 7mm.The setting of image-side numerical aperture NA=0.25 is effectively guaranteed luminous flux, difference is expanded the mating plate than under
It is attained by due layer and cuts ability；Back work distance can not only ensure sample placement space from the setting more than or equal to 7mm, but also not
Whole system can be made to seem lengthy.
To sum up, the order passed through in the technical program by light, the light respectively sent from laser light source, by four constituent elements
Mechanical compensation realizes the change of outgoing laser beams bore without burnt zoom beam-expanding system, then is revolved by one by rotation axis of optical axis
Turn 90 ° of cylindrical lens and form a kind of lamella light, the lamella light formed again by an aplanasia microcobjective go abatement due to
The spherical aberration that no burnt zoom beam-expanding system and cylindrical lens produce；Along optical axis direction, incident laser enters without burnt zoom beam-expanding system
It is later collimated, then it is compressed in its focal plane by cylindrical lens.Microcobjective is placed on cylindrical lens post-compensation system spherical aberration,
So that the light intensity of whole mating plate keeps uniformity.Lighting system is except a cylindrical lens are employed, its lap is all sphere, this causes
The processing of whole system and assembly cost are greatly lowered.
Brief description of the drawings
Fig. 1：The mating plate 3D figures that mating plate illumination microscope is formed；
Fig. 2：System it is low expand than when light path schematic diagram；
Fig. 3：System expanded in than when light path schematic diagram；
Fig. 4：System height expand than when light path schematic diagram；
Fig. 5：Point range figure of the system in low expand than (1)；
Fig. 6：Point range figure when system is expanded in than (6)；
Fig. 7：Point range figure of the system when height is expanded than (10)；
Fig. 8：Physical optics of the system in low expand than (1) propagates (POP) figure；
Fig. 9：Physical optics when system is expanded in than (6) propagates (POP) figure；
Figure 10：Physical optics of the system when height is expanded than (10) propagates (POP) figure；
Wherein:
1 is first fixed group；
2 be zoom group；
3 be compensation group；
4 be after fix group；
5 be cylindrical lens；
6 be microcobjective.
Embodiment
The invention will be further described with reference to the accompanying drawings and embodiments：
Embodiment one：
A kind of variable mating plate thickness and the mating plate of length illuminate microscopical lighting system, as shown in Figure 1, by thing side to picture
Side is included along optical axis arrangement successively：Laser light source, without burnt zoom beam-expanding system, cylindrical lens 5, microcobjective 6.The laser
Optical source wavelength λ=532nm, waist radius 0.5mm.No burnt zoom beam-expanding system for full spherical mirror four constituent element mechanical compensations without
Burnt zoom beam-expanding system, the four constituent element mechanical compensations fixed group before being followed successively by without burnt zoom beam-expanding system from thing side to image side
1st, zoom group 2, compensation group 3, rear fixed group 4, each constituent element focal length are followed successively by positive and negative, negative, positive, are sent from the laser light source
Light is fixed at the front focus of group after group, zoom group, compensation group are fixed before without burnt zoom beam-expanding system and is imaged on, from rear fixation
The light of group outgoing is collimated light beam, by burnt before being compressed in postposition microcobjective as the cylindrical lens that rotation axis is rotated by 90 ° using optical axis
At point, the spherical aberration introduced without burnt zoom beam-expanding system and cylindrical lens is eliminated finally by anaberration microcobjective, is obtained required
The mating plate wanted.
A kind of variable mating plate thickness and the mating plate of length illuminate microscopical lighting system, by attached drawing 2- Fig. 4 it is low/medium/
Height is expanded than light path schematic diagram, designs a kind of mating plate illumination microscope illumination system, and optical system structure parameter is as shown in table 1,
In addition to being wherein cylinder except 16 faces, its lap is sphere.Wherein：Diaphragm face is located at face 1, and face 2 to face 15 expands for system zoom
System, face 16 to face 17 are the cylindrical lens being rotated by 90 ° using optical axis as rotation axis.Virtual face 18 is guarantee cylindrical lens to microcobjective
Between distance be equal to the sum of objective focal length and cylindrical lens focal length set by, face 19 to face 24 is aplanasia microcobjective, and face 25 is light
Girdle the waist place for piece center, i.e. image space.Table 2 lists face sequence number 5,7,11 in table 1 and corresponds to three airspaces, is respectively that zoom expands
When before the distance between fixed group and zoom group, zoom group and compensation group, compensation group and rear fixed group.Structure 1-3 is respectively to become
Burnt beam-expanding system is being expanded than the airspace for 1,6 and 10.
1 optical system structure parameter of table
| Face sequence number | Vertex curvature radius R (mm) | Thickness (mm) | Half bore | Material |
| 1 | Infinity | 12 | 2 | |
| 2 | -6.442 | 1 | 2 | H-LAK11 |
| 3 | -7.214 | 2 | 2.1 | |
| 4 | 9.561 | 1 | 2.2 | H-ZK9B |
| 5 | 17.024 | Variable air interval | 2.1 | |
| 6 | 7.612 | 0.8 | 1.6 | H-BAK4 |
| 7 | 3.915 | Variable air interval | 1.5 | |
| 8 | 6.724 | 1.8 | 2.6 | H-LAK51A |
| 9 | 5.808 | 7.7 | 2.4 | |
| 10 | -12.631 | 3 | 3.2 | H-LAK51A |
| 11 | 19.772 | Variable air interval | 3.6 | |
| 12 | -110.458 | 10.9 | 15 | H-ZLAF71 |
| 13 | -53.082 | 3.5 | 17.6 | |
| 14 | -4176.809 | 9.6 | 19.1 | H-ZLAF71 |
| 15 | -78.267 | 5 | 20 | |
| 16 | Infinity/76.793 | 5 | 20 | H-K9L |
| 17 | Infinity | 145.6 | 19.8 | |
| 18 | Infinity | 73.4 | 19.951 | |
| 19 | 63.305 | 19.1 | 20 | H-BAK2 |
| 20 | -75.330 | 20 | 20 | ZF2 |
| 21 | -552.152 | 41.3 | 20 | |
| 22 | 30.054 | 16.9 | 20 | H-BAK2 |
| 23 | -27.715 | 20.000 | 20 | ZF2 |
| 24 | 51.641 | 9.1 | 20 | |
| 25 | Infinity | / | / | / |
2 difference of table expand than when airspace (unit：mm)
Fig. 5-Fig. 7 for the lighting system respectively it is basic, normal, high expand than when point range figure, three kinds of structures of corresponding table 2.From
Difference expand than point range figure in as can be seen that with expand than increase, the length of point range figure shortening.Indicate and expand ratio
The length of bigger mating plate is shorter, and thickness is thinner.
The physical optics of the lighting system propagates (POP) figure respectively as Figure 8-Figure 10, three kinds of structures of corresponding table 2.
Scheme from POP it can be seen that it is basic, normal, high expand than when whole system waist radius realize change from big to small, Rayleigh
Distance from big to small, can meet the illumination to different size samples in a certain range.
From the point of view of design result, which realizes mating plate size in the case of the complicated zoom system, pancreatic system of no addition
Change, reduce material and processing cost.Meanwhile system does not add yet and is difficult to the aspherical of adjustment.Entirely become in this example
The overall length of burnt beam-expanding system is not above 120mm, compared to other overall lengths in the zoom beam-expanding system of 200mm or so, shortens
80mm, makes lighting system compacter.
The technical program unspecified part belongs to technology well known to those skilled in the art.
Claims (6)
1. a kind of variable mating plate thickness and the mating plate of length illuminate microscopical lighting system, edge is included by thing side to image side successively
Optical axis arrangement：Laser light source, without burnt zoom beam-expanding system, cylindrical lens, microcobjective, wherein described expand without burnt zoom
System expands for four constituent element mechanical compensations of full spherical mirror without burnt zoom beam-expanding system, the four constituent element mechanical compensations without burnt zoom
Beam system fixes group, zoom group, compensation group and fixes group, described first fixed group, zoom afterwards before being followed successively by from thing side to image side
The focal length of group, compensation group and rear fixed group is followed successively by positive and negative, negative, positive, and the light sent from the laser light source passes through without burnt zoom
The light of beam-expanding system outgoing is collimated light beam, and the microcobjective is aplanasia microcobjective.
2. variable mating plate thickness according to claim 1 and the mating plate of length illuminate microscopical lighting system, its feature
It is：The incident light that the laser light source is sent shoot laser beam bore after without burnt zoom beam-expanding system is 1-10mm.
3. a kind of variable mating plate thickness according to claim 2 and the mating plate of length illuminate microscopical lighting system, its
It is characterized in that：The zoom ratio without burnt zoom beam-expanding system is 10 times.
4. variable mating plate thickness according to claim 3 and the mating plate of length illuminate microscopical lighting system, its feature
It is：The cylindrical lens are plano-convex cylindrical lens.
5. variable mating plate thickness according to claim 4 and the mating plate of length illuminate microscopical lighting system, its feature
It is：The microcobjective is image-side numerical aperture NA=0.25, and back work distance is from the aplanatic lens more than or equal to 7mm.
6. the mating plate of variable mating plate thickness and length according to one of claim 1-5 illuminates microscopical lighting system,
Wherein described first fixed group is made of an one negative, positive two panels lens, and zoom group is a piece of negative lens, compensation group by it is one negative, one
Just two pieces of lens composition, rear fixed group by one just, a negative two panels lens form.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109060736A (en) * | 2018-06-27 | 2018-12-21 | 北京天天极因科技有限公司 | Mating plate fluorescent microscopic imaging device and detection method for the imaging of transparence drop |
| CN109143562A (en) * | 2018-09-12 | 2019-01-04 | 苏州大学 | A kind of variable mating plate lighting system based on zoom principle |
| CN109884801A (en) * | 2018-12-31 | 2019-06-14 | 苏州大学 | Continuous vari-focus laser shaping system |
| CN110416872A (en) * | 2019-07-31 | 2019-11-05 | 天津大学 | Radian and the tunable arc beam delivery system of width |
| CN110543004A (en) * | 2019-08-27 | 2019-12-06 | 杭州图谱光电科技有限公司 | Digital microscope objective with high magnification and large zoom ratio |
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4353617A (en) * | 1980-11-18 | 1982-10-12 | Canon Kabushiki Kaisha | Optical system capable of continuously varying the diameter of a beam spot |
| JPH0961709A (en) * | 1995-08-24 | 1997-03-07 | Dainippon Screen Mfg Co Ltd | Variable power beam expander |
| US6307682B1 (en) * | 2000-02-16 | 2001-10-23 | Silicon Valley Group, Inc. | Zoom illumination system for use in photolithography |
| CN101107572A (en) * | 2005-01-31 | 2008-01-16 | 奥林巴斯株式会社 | Illumination optical apparatus and optical apparatus |
| WO2014012417A1 (en) * | 2012-07-18 | 2014-01-23 | 深圳市大族激光科技股份有限公司 | Green laser zoom beam expanding system and laser processing equipment |
| CN204178041U (en) * | 2014-11-04 | 2015-02-25 | 温州生物材料与工程研究所 | Variable power expander lens |
| EP2997880A1 (en) * | 2014-09-19 | 2016-03-23 | Carl Zeiss Meditec AG | Optical system, comprising a microscopy system and an oct system |
| CN206696536U (en) * | 2017-04-13 | 2017-12-01 | 上海仪万光电科技有限公司 | A kind of Ultra-Violet Laser continuous zoom beam expanding lens |
| CN107490566A (en) * | 2017-07-21 | 2017-12-19 | 中国科学院上海光学精密机械研究所 | Airy beam mating plate illumination microscopic imaging device based on binary optical elements |
-
2018
- 2018-01-12 CN CN201810031689.2A patent/CN107976794B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4353617A (en) * | 1980-11-18 | 1982-10-12 | Canon Kabushiki Kaisha | Optical system capable of continuously varying the diameter of a beam spot |
| JPH0961709A (en) * | 1995-08-24 | 1997-03-07 | Dainippon Screen Mfg Co Ltd | Variable power beam expander |
| US6307682B1 (en) * | 2000-02-16 | 2001-10-23 | Silicon Valley Group, Inc. | Zoom illumination system for use in photolithography |
| CN101107572A (en) * | 2005-01-31 | 2008-01-16 | 奥林巴斯株式会社 | Illumination optical apparatus and optical apparatus |
| WO2014012417A1 (en) * | 2012-07-18 | 2014-01-23 | 深圳市大族激光科技股份有限公司 | Green laser zoom beam expanding system and laser processing equipment |
| EP2997880A1 (en) * | 2014-09-19 | 2016-03-23 | Carl Zeiss Meditec AG | Optical system, comprising a microscopy system and an oct system |
| CN204178041U (en) * | 2014-11-04 | 2015-02-25 | 温州生物材料与工程研究所 | Variable power expander lens |
| CN206696536U (en) * | 2017-04-13 | 2017-12-01 | 上海仪万光电科技有限公司 | A kind of Ultra-Violet Laser continuous zoom beam expanding lens |
| CN107490566A (en) * | 2017-07-21 | 2017-12-19 | 中国科学院上海光学精密机械研究所 | Airy beam mating plate illumination microscopic imaging device based on binary optical elements |
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| CN109060736A (en) * | 2018-06-27 | 2018-12-21 | 北京天天极因科技有限公司 | Mating plate fluorescent microscopic imaging device and detection method for the imaging of transparence drop |
| CN109143562A (en) * | 2018-09-12 | 2019-01-04 | 苏州大学 | A kind of variable mating plate lighting system based on zoom principle |
| CN109143562B (en) * | 2018-09-12 | 2020-12-15 | 苏州大学 | Variable light sheet lighting system based on zooming principle |
| CN109884801A (en) * | 2018-12-31 | 2019-06-14 | 苏州大学 | Continuous vari-focus laser shaping system |
| CN110416872A (en) * | 2019-07-31 | 2019-11-05 | 天津大学 | Radian and the tunable arc beam delivery system of width |
| CN110543004A (en) * | 2019-08-27 | 2019-12-06 | 杭州图谱光电科技有限公司 | Digital microscope objective with high magnification and large zoom ratio |
| CN110865464A (en) * | 2019-11-25 | 2020-03-06 | 深圳市深大极光科技有限公司 | Laser projection device |
| CN113126273A (en) * | 2019-12-30 | 2021-07-16 | 长春长光华大智造测序设备有限公司 | Bar-shaped illumination optical system of microscope objective |
| CN113126273B (en) * | 2019-12-30 | 2022-12-23 | 长春长光华大智造测序设备有限公司 | Bar-shaped lighting optical system of microobjective |
| CN111240000A (en) * | 2020-03-03 | 2020-06-05 | 长春理工大学 | Fluorescent microscope capable of continuously changing magnification |
| CN115291373A (en) * | 2022-07-28 | 2022-11-04 | 广州长步道光学科技有限公司 | Focal length extension subassembly of FA industrial lens |
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