CN107970298A - A kind of Xuancheng's pawpaw ball with lipid-reducing function - Google Patents
A kind of Xuancheng's pawpaw ball with lipid-reducing function Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The present invention provides a kind of Xuancheng's pawpaw ball with lipid-reducing function, it is prepared by the raw material of following parts by weight：20 30 parts of Xuancheng's pawpaw, 10 20 parts of Siraitia grosvenorii, 10 18 parts of fructus cannabis, 8 12 parts of cape jasmine, 12 20 parts of elscholtiza, 5 10 parts of field thistle, and its preparation method is disclosed, the present invention has effect for reducing fat.
Description
Technical field
The present invention relates to health product technology field, and in particular to a kind of Xuancheng's pawpaw ball with lipid-reducing function.
Background technology
Obesity is a kind of chronic metabolic disease as caused by many factors, with the volume and cell of body fat cell
Number increase causes the percentage of body fat percentage of liveweight to increase extremely and with the characteristics of some parts excessively deposit fat.Simple obesity is suffered from
The distribution of person's body fat does not have endocrine disturbance phenomenon, often has obesity without dysbolism disease, its family yet than more uniform
Medical history.The cause of disease：1. inherent cause：Multifactor heredity is regarded as mostly, is not by one when the constitution of parent entails children
Gene, but by a variety of genes come determinant woman's constitution, so referred to as multiple-factor inheritance, such as non-insulin according to
Rely patients with type Ⅰ DM, obesity, just belong to this kind of heredity.There is people obesity in parent, then children have 40% fat probability, if father
Female both sides are all fat, and the probability that children may be fat is increased to 70%~80%.2. the factor of social environment：Many people suffer from
Can eat be exactly good fortune idea, social now, food species are various, and cuisines of all kinds are often luring you, along with having a big dinner
Almost become a kind of universal amusement, this becomes the main reason for causing obesity certainly.3. the factor of psychology：In order to release the heart
Unstable in worry, mood in feelings, many people are also to be given vent to eating.This is all to cause hyperalimentation and cause obesity
The reason for.4. the factor related with movement：Movement helps consumption fat, among daily life, with the prosperity of the vehicles,
The mechanization of work, housework amount mitigation etc. so that the chance of human consumption heat is less, on the other hand because of the energy absorbed simultaneously
Do not reduce, and formed fat.Fat to cause daily activity more to ease up slow, sluggish, lowers the consumption of heat more again, causes pernicious
Circulation, encourages the generation of obesity.
The content of the invention
Goal of the invention：To solve the above-mentioned problems, the present inventor has found that the present invention has lipid-reducing function through studying for a long period of time, is
It is an object of the invention to provide a kind of Xuancheng's pawpaw ball with lipid-reducing function for this.
Technical solution：The purpose of the present invention is what is realized by following scheme：
A kind of Xuancheng's pawpaw ball with lipid-reducing function, it is prepared by the raw material of following parts by weight：Xuancheng's pawpaw 20-30
Part, 10-20 parts of Siraitia grosvenorii, 10-18 parts of fructus cannabis, 8-12 parts of cape jasmine, 12-20 parts of elscholtiza, 5-10 parts of field thistle.
The Xuancheng's pawpaw ball with lipid-reducing function, it is prepared by the raw material of following parts by weight：25 parts of Xuancheng's pawpaw,
15 parts of Siraitia grosvenorii, 14 parts of fructus cannabis, 10 parts of cape jasmine, 16 parts of elscholtiza, 8 parts of field thistle.
The Xuancheng's pawpaw ball with lipid-reducing function, big honeyed bolus is made in addition auxiliary material after the raw material is extracted.
The Xuancheng's pawpaw ball with lipid-reducing function, the auxiliary material are the one of lactose, sucrose, glucose and stevioside
Kind is several.
The Xuancheng's pawpaw ball with lipid-reducing function, preparation method include the following steps：Take Xuancheng's pawpaw, Siraitia grosvenorii, fire fiber crops
Benevolence, cape jasmine, elscholtiza, field thistle medicinal material merge, and add water to cook twice, collecting decoction, relative density is when being concentrated under reduced pressure into 65 DEG C
The medicinal extract of 1.15-1.20, adds ethanol the percent by volume of alcohol content is reached 75-85%, stirs, and stands, filtering, and filtrate decompression is dense
Relative density is 1.25-1.30 when being reduced to 65 DEG C, and recycles ethanol, obtains concentrate, spray drying, and big honey is made in addition auxiliary material
Ball.
The Xuancheng's pawpaw ball with lipid-reducing function, in preparation method step, decocting condition is：For the first time plus water is medicinal material
8-12 times of weight is measured, and decocts 1-2h, is added 6-10 times that water is medicinal material weight to measure for the second time, is decocted 1-2h.
The Xuancheng's pawpaw ball with lipid-reducing function, in preparation method step, spray drying condition is：Inlet air temperature is
80-120 DEG C, leaving air temp is 80-90 DEG C, and temperature of charge is 70-90 DEG C, and atomizing pressure is 0.2-0.4 megapascal, and spray velocity is
5-10ml/s。
Application of the Xuancheng's pawpaw ball with lipid-reducing function in lipid-reducing function health products are prepared.
Xuancheng's pawpaw contains 19 kinds of amino acid, 18 kinds of mine trace elements, and vitamin C, while also contains
Saponin, flavones, malic acid, oleanolic acid, citric acid, citric acid, tartaric acid, ascorbic acid, fumaric acid, tannin etc., contain
There are catalase, phenol oxidase, oxidizing ferment, especially rich in hepatocuprein (SOD) and oleanolic acid.Its SOD's contains
Amount is impayable in all fruit in the world, and the content of one gram of Xuancheng's pawpaw fresh fruit SOD is up to 3227 international units.SOD is
The core substance of modern beauty beauty treatment product, can effectively eliminate superfluous free radical in vivo, promote body cell renewal.Olive
Acid has broad-spectrum antibacterial action, has the effects such as protect liver drop enzyme, promoting immunity, anti-inflammatory, reducing blood lipid blood glucose.Siraitia grosvenorii, Curcurbitaceae are more
The fruit of year raw liana.Alias sweating fruit, balloonvine heartseed herb, Semen Momordicae, invaluable, arhat table, naked tortoise bar, are described as by people
" angle fruit ", its leaf is heart-shaped, dioecism, summer-flowering, seed in autumn.Mainly originate in Guangxi Zhuang Autonomous Region Guilin City Yongfu
Longjiang township of county, dragon victory and hundred Shou Deng towns, Yongfu county He Longsheng counties are that township's plantation history of Siraitia grosvenorii is longer, wherein Yongfu kind
Planting Siraitia grosvenorii has had more than 300 years history, and Long Sheng counties plantation Siraitia grosvenorii has had more than 200 years history, Chinese 90 percent sieve
Chinese fruit originates in Yongfu county He Longsheng counties, and Siraitia grosvenorii is the rare local and special products in Guilin, and the medicine-food two-purpose material that country ratifies in the first batch
One of material, its primary efficacy is can be relieving cough and reducing sputum.Fruits nutrition value is very high, containing abundant vitamin C (in every 100 grams of fresh fruits
Containing 400 milligrams~500 milligrams) and glucoside, fructose, glucose, protein, lipid etc..Fructus cannabis is moraceae plants hemp
The dry mature seed of Cannabis sativa L..It is distributed in the ground such as northeast, North China, East China, Central-South.With relaxing bowel it
Effect.It is usually used in blood deficiency and depleted fluid, dry constipation of intestines.Cape jasmine is the fruit of madder wort cape jasmine.The fruit of cape jasmine is traditional Chinese medicine,
Belong to the l batches of medicine-food two-purpose resources that the Ministry of Public Health promulgates, there is the effect such as protect liver, cholagogic, decompression, calmness, hemostasis, detumescence.In
Doctor's clinic is usually used in treating the diseases such as icteric hepatitis, bruise, hypertension, diabetes.The base of glycosides containing safran, can make yellow
Dyestuff.Elscholtiza can be used as medicine, and have inducing sweat and dispelling exogenous evils, dampness elimination is with, inducing diuresis for removing edema effect.Cure mainly：The cold drink of Xia Yue senses is cold, has a headache and fever,
Aversion to cold is lossless, feeling of stuffiness in chest abdominal pain, vomiting and diarrhoea, oedema, tinea pedis.Field thistle sweet, bitter, cold.Converge to heart and liver channels.Energy cooling blood and hemostasis, dissolving stasis disappear
It is swollen.For bleeding from five sense organs or subcutaneous tissue, spit blood, hematuria, has blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus.Xuancheng's pawpaw of the present invention, Siraitia grosvenorii are monarch
Medicine, fructus cannabis, cape jasmine are ministerial drug, and elscholtiza, field thistle are adjuvant, and full side has lipid-reducing function.
Embodiment
Form by the following examples, is described in further detail the above of the present invention again, but should not be by this
The scope for being interpreted as the above-mentioned theme of the present invention is only limitted to following example, and all technologies for being realized based on the above of the present invention are equal
Belong to the scope of the present invention.
Embodiment 1：Take 20 parts of Xuancheng's pawpaw, 20 parts of Siraitia grosvenorii, 10 parts of fructus cannabis, 12 parts of cape jasmine, 12 parts of elscholtiza, 10 parts of field thistle
Medicinal material merges, and adds water to cook twice, and first time plus water are 10 times of amounts of medicinal material weight, decoct 1.5h, for the second time plus water is medicinal material
8 times of weight are measured, decoction 1.5h, collecting decoction, and relative density is 1.15 when being concentrated under reduced pressure into 65 DEG C at 0.07MPa, 60-70 DEG C
Medicinal extract, add 95% (v/v) ethanol to make alcohol content up to 75% (v/v), stirring, stand 24 it is small when, filtering, filtrate 0.07MPa,
It is 1.25 to be concentrated under reduced pressure under the conditions of 65 DEG C to relative density at 65 DEG C, and recycles ethanol, obtains concentrate, concentrate is sprayed dry
It is dry that (condition is that inlet air temperature is 100 DEG C, and leaving air temp is 85 DEG C, and temperature of charge is 80 DEG C, and atomizing pressure is 0.2 megapascal, spraying
Speed is 5ml/s.), appropriate lactose is added, big honeyed bolus is made.
Embodiment 2：Take 5 parts of 30 parts of Xuancheng's pawpaw, 10 parts of Siraitia grosvenorii, 18 parts of fructus cannabis, 8 parts of cape jasmine, 20 parts of elscholtiza, field thistle medicines
Material merges, and adds water to cook twice, and for the first time plus water is 8 times of amounts of medicinal material weight, decocts 1h, second plus water are medicinal material weight
6 times are measured, decoction 1h, collecting decoction, and relative density is 1.20 when being concentrated under reduced pressure into 65 DEG C at 0.07MPa, 60-70 DEG C, adds 95%
(v/v) ethanol makes alcohol content be stirred, when standing 24 is small, filtering, filtrate subtracts under the conditions of 0.07MPa, 65 DEG C up to 80% (v/v)
It is 1.30 that pressure, which is condensed into relative density at 65 DEG C, and recycles ethanol, obtains concentrate, concentrate is spray-dried (condition be into
Air temperature is 110 DEG C, and leaving air temp is 80 DEG C, and temperature of charge is 70 DEG C, and atomizing pressure is 0.3 megapascal, and spray velocity is
7.5ml/s.), appropriate sucrose is added, big honeyed bolus is made.
Embodiment 3：Take 25 parts of Xuancheng's pawpaw, 15 parts of Siraitia grosvenorii, 14 parts of fructus cannabis, 10 parts of cape jasmine, 16 parts of elscholtiza, 8 parts of field thistle
Medicinal material merges, and adds water to cook twice, and first time plus water are 12 times of amounts of medicinal material weight, decoct 2h, for the second time plus water is medicinal material weight
10 times of amount are measured, decoction 2h, collecting decoction, and relative density is 1.20 when being concentrated under reduced pressure into 65 DEG C at 0.07MPa, 60-70 DEG C
Medicinal extract, adding 95% (v/v) ethanol to make alcohol content, stirring, when standing 24 is small, filtering, filtrate is in 0.07MPa, 65 up to 85% (v/v)
It is 1.30 to be concentrated under reduced pressure under the conditions of DEG C to relative density at 65 DEG C, and recycles ethanol, obtains concentrate, concentrate is spray-dried
(condition is that inlet air temperature is 120 DEG C, and leaving air temp is 90 DEG C, and temperature of charge is 90 DEG C, and atomizing pressure is 0.4 megapascal, spraying speed
Spend for 10ml/s.), appropriate stevioside is added, big honeyed bolus is made.
Embodiment 4：Influence of the Xuancheng's pawpaw ball of the present invention to high fat mouse blood ester
Experimental animal：Kunming mouse, male, weight 18-22g, Shanghai Slac Experimental Animal Co., Ltd. provide.
Experimental drug：Xuancheng's pawpaw ball of the present invention and control group are prepared by 1,2,3 method of above-described embodiment, Zhibituo,
Produced by Chengdu Di Aojiuhong pharmaceutical factories, lot number 1604202, specification：Every dress 0.24g.High lipid food：10% yolk powder,
1.2% cholesterol, 10% lard, 78% basal feed.
Dosage：10g/kg.
Main agents：T-CHOL (TC), triglycerides (TG), highly dense low fat protein cholesterol (HDL-C) and low-density
Lipoprotein (LDL-C) assay kit, Beijing Zhong Sheng bio-engineering corporations product.
Experimentation：Healthy mice 60 is selected, 10 is separated at random and is only used as normal group, remaining 50 mouse, raises with high fat
Feed, normal water, modeling 14d, obtains model group.After model causes, 5 groups are randomly divided into：Model group, embodiment 1,4,5 groups,
Positive drug Zhibituo group (340mg/kg), by above-mentioned dosage gastric infusion, the water of Normal group and model group to same volume, often
Its morning 1 time, continuous 30d, takes hematometry each mouse TC, TG, HDL-C, LDL-C, and each group of data is represented with means standard deviation, group
Between carry out t tests.It the results are shown in Table
Influence (n=10) of the Xuancheng's pawpaw ball of the present invention to Experimental Hyperlipemia mouse blood ester level
Note:The * p compared with model group<0.05**<0.01；The △ compared with Zhibituo group<0.05△△<0.01
Conclusion：Xuancheng's pawpaw ball of the present invention can reduce Experimental Hyperlipemia mouse blood ester level.
Claims (8)
1. a kind of Xuancheng's pawpaw ball with lipid-reducing function, it is characterised in that it is prepared by the raw material of following parts by weight：A surname
20-30 parts of pawpaw, 10-20 parts of Siraitia grosvenorii, 10-18 parts of fructus cannabis, 8-12 parts of cape jasmine, 12-20 parts of elscholtiza, 5-10 parts of field thistle.
2. according to claim 1 have lipid-reducing function Xuancheng's pawpaw ball, it is characterised in that it by following parts by weight original
Material is prepared：25 parts of Xuancheng's pawpaw, 15 parts of Siraitia grosvenorii, 14 parts of fructus cannabis, 10 parts of cape jasmine, 16 parts of elscholtiza, 8 parts of field thistle.
3. the Xuancheng's pawpaw ball according to claim 1 or claim 2 with lipid-reducing function, it is characterised in that after the raw material is extracted
Big honeyed bolus is made in addition auxiliary material.
4. the Xuancheng's pawpaw ball with lipid-reducing function according to claim 3, it is characterised in that the auxiliary material for lactose,
The one or more of sucrose, glucose and stevioside.
5. the Xuancheng's pawpaw ball with lipid-reducing function of claim 1 or 2, it is characterised in that preparation method includes the following steps：
Take Xuancheng's pawpaw, Siraitia grosvenorii, fructus cannabis, cape jasmine, elscholtiza, field thistle medicinal material to merge, add water to cook twice, collecting decoction, is concentrated under reduced pressure
To the medicinal extract that relative density at 65 DEG C is 1.15-1.20, add ethanol the percent by volume of alcohol content is reached 75-85%, stir, it is quiet
To put, filter, relative density is 1.25-1.30 when filtrate decompression is concentrated into 65 DEG C, and recycles ethanol, obtains concentrate, spray drying,
Big honeyed bolus is made in addition auxiliary material.
6. there is the Xuancheng's pawpaw ball of lipid-reducing function according to claim 5, it is characterised in that in preparation method step, decoct
Condition is：First time adds 8-12 times that water is medicinal material weight to measure, and decocts 1-2h, adds water for the second time for 6-10 times of medicinal material weight
Amount, decocts 1-2h.
7. there is the Xuancheng's pawpaw ball of lipid-reducing function according to claim 5, it is characterised in that in preparation method step, spraying
Drying condition is：Inlet air temperature is 80-120 DEG C, and leaving air temp is 80-90 DEG C, and temperature of charge is 70-90 DEG C, and atomizing pressure is
0.2-0.4 megapascal, spray velocity 5-10ml/s.
8. application of the Xuancheng's pawpaw ball with lipid-reducing function of claim 1 or 2 in lipid-reducing function health products are prepared.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695373A (en) * | 2009-10-30 | 2010-04-21 | 太原纠偏食品开发有限公司 | Food additive for adjusting and reducing blood fat and preparation method thereof |
| CN107006654A (en) * | 2017-05-20 | 2017-08-04 | 宣城华科宣木瓜生物科技有限公司 | Xuancheng's pawpaw ginger tea and preparation method thereof |
| CN107252020A (en) * | 2017-08-17 | 2017-10-17 | 宁国平衡健康管理有限公司 | A kind of Xuancheng's pawpaw beverage and preparation method thereof |
-
2017
- 2017-11-20 CN CN201711154129.8A patent/CN107970298A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695373A (en) * | 2009-10-30 | 2010-04-21 | 太原纠偏食品开发有限公司 | Food additive for adjusting and reducing blood fat and preparation method thereof |
| CN107006654A (en) * | 2017-05-20 | 2017-08-04 | 宣城华科宣木瓜生物科技有限公司 | Xuancheng's pawpaw ginger tea and preparation method thereof |
| CN107252020A (en) * | 2017-08-17 | 2017-10-17 | 宁国平衡健康管理有限公司 | A kind of Xuancheng's pawpaw beverage and preparation method thereof |
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