CN107252020A - A kind of Xuancheng's pawpaw beverage and preparation method thereof - Google Patents
A kind of Xuancheng's pawpaw beverage and preparation method thereof Download PDFInfo
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- CN107252020A CN107252020A CN201710708350.7A CN201710708350A CN107252020A CN 107252020 A CN107252020 A CN 107252020A CN 201710708350 A CN201710708350 A CN 201710708350A CN 107252020 A CN107252020 A CN 107252020A
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- pawpaw
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- 244000189799 Asimina triloba Species 0.000 title claims abstract description 34
- 235000006264 Asimina triloba Nutrition 0.000 title claims abstract description 34
- 235000009467 Carica papaya Nutrition 0.000 title claims abstract description 34
- 235000013361 beverage Nutrition 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims description 6
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- 235000001938 Citrus medica Nutrition 0.000 claims abstract description 9
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- 239000000741 silica gel Substances 0.000 claims description 18
- 229910002027 silica gel Inorganic materials 0.000 claims description 18
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- 238000003304 gavage Methods 0.000 description 5
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- 210000004698 lymphocyte Anatomy 0.000 description 4
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- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 description 3
- JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
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- 238000010828 elution Methods 0.000 description 3
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- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
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- 210000000952 spleen Anatomy 0.000 description 3
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- LAZPBGZRMVRFKY-HNCPQSOCSA-N Levamisole hydrochloride Chemical group Cl.C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 LAZPBGZRMVRFKY-HNCPQSOCSA-N 0.000 description 2
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- 229930003268 Vitamin C Natural products 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
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- 235000013399 edible fruits Nutrition 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
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- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000021022 fresh fruits Nutrition 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 235000011087 fumaric acid Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 229960003734 levamisole hydrochloride Drugs 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
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- 230000001590 oxidative effect Effects 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
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- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
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- 210000004988 splenocyte Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention provides a kind of Xuancheng's pawpaw beverage, is extracted and is prepared from by following bulk drugs weight：The 25g of Xuancheng's pawpaw 15, the 20g of lily 10, the 15g of Buddha's hand 5, the 8g of SEMEN SINAPIS ALBAE 4, the 10g of fructus amomi 6, the 25g of brush-cherry seed 20, the 35g of emblic 20, the 12g of tamarind 8, the 20g of the membrane of a chicken's gizzard 10, with raising immunity.
Description
Technical field
The present invention relates to food extractive technique field, and in particular to a kind of Xuancheng's pawpaw beverage and preparation method thereof.
Background technology
Xuancheng's pawpaw originates in the small towns such as the Shui Dong of Xuanzhou District, Sun Bu, new field, all kings, Xi Kou, Jin Ba, and Jingxian County, Ningguo also have few
Amount production.Xuancheng's pawpaw is warm-natured, sour-puckery flavor, stimulates the circulation of the blood and cause the muscles and joints to relax, the disease such as wind-dispelling arthritis with fixed pain caused by dampness.Ancient medicine scholar Tao Hongjing, Su Song, Li Shi
Treasure has higher rating.《Compendium of Materia Medica》Carry：" pawpaw has it everywhere, and Xuancheng person is optimal ", therefore have the title of Xuancheng's pawpaw.Xuanzhou District
The Xuancheng's pawpaw of plantation, existing more than 1500 years history, early in the Northern and Southern Dynasties, period has been set to " tribute ".Xuancheng's pawpaw contains 19 kinds of amino
Acid, 18 kinds of mine trace elements, and vitamin C, while also containing saponin, flavones, malic acid, oleanolic acid, Chinese holly
Rafter acid, citric acid, tartaric acid, ascorbic acid, fumaric acid, tannin etc., containing catalase, phenol oxidase, oxidizing ferment,
Especially it is rich in hepatocuprein (SOD) and oleanolic acid.Its SOD content is unrivaled in all fruit in the world
, one gram of Xuancheng's pawpaw fresh fruit SOD content is up to 3227 international units.SOD is the core substance of modern beauty beauty treatment product, can
Effectively to eliminate superfluous free radical in vivo, promote body cell and update.Oleanolic acid has broad-spectrum antibacterial action, with protect liver drop
Enzyme, promoting immunity, anti-inflammatory, reducing blood lipid blood glucose etc. are acted on.Folk prescription is relatively more in the market, and compound is seldom.
The content of the invention
Goal of the invention：In order to solve the above problems, it is an object of the invention to provide a kind of Xuancheng's pawpaw beverage and its preparation
Method.
Technical scheme：The purpose of the present invention is realized by following scheme：
A kind of Xuancheng's pawpaw beverage, is extracted by following bulk drugs weight and is prepared from：Xuancheng's pawpaw 15-25g, lily
10-20g, Buddha's hand 5-15g, SEMEN SINAPIS ALBAE 4-8g, fructus amomi 6-10g, brush-cherry seed 20-25g, emblic 20-35g, tamarind 8-12g, chicken
Interior golden 10-20g.
A kind of Xuancheng's pawpaw beverage, is extracted by following bulk drugs weight and is prepared from：Xuancheng's pawpaw 20g, lily 15g,
Buddha's hand 10g, SEMEN SINAPIS ALBAE 6g, fructus amomi 8g, brush-cherry seed 20g, emblic 30g, tamarind 10g, the membrane of a chicken's gizzard 15g.
A kind of Xuancheng's pawpaw beverage, preparation method is：The water for material dosing 10 times of weight of material of getting it filled, soaks 0.5h, decocts 1 small
When, filtering, the dregs of a decoction add the water of 8 times of weight of medicinal material, decoct 1 hour, decoction is filtered out, and merge decoction liquor twice, are concentrated into 60
DEG C relative density is 1.05, plus the percent by volume that ethanol makes alcohol content is stirred up to 75%, is stood, filtering, filtrate is concentrated into 65
DEG C when relative density be 1.25, and reclaim ethanol, obtain concentrate, it is refined using silica gel, selected silica gel is loaded into resin in advance
In post, while by after the purified water dilution of the concentrate, by reverse phase silica gel post, removing the impurity in liquid, collecting all
Efflux, adds sucrose, is prepared into Xuancheng's pawpaw beverage.
The Xuancheng's pawpaw beverage is preparing the application in improving immunity food.
Beneficial effect：Xuancheng's pawpaw of the present invention, lily, Buddha's hand, SEMEN SINAPIS ALBAE, fructus amomi, brush-cherry seed, emblic, tamarind, the membrane of a chicken's gizzard
Compatibility, can improve immunity.
Embodiment
Form, is described in further detail again to the above of the invention by the following examples, but should not be by this
The scope for being interpreted as above-mentioned theme of the invention is only limitted to following example, and all technologies realized based on the above of the present invention are equal
Belong to the scope of the present invention.
Embodiment 1：Take Xuancheng's pawpaw 15g, lily 20g, Buddha's hand 5g, SEMEN SINAPIS ALBAE 8g, fructus amomi 6g, brush-cherry seed 25g, emblic
20g, tamarind 12g, the membrane of a chicken's gizzard 10g, the water of 10 times of weight of dosing material soak 0.5h, decoct 1 hour, and filtering, the dregs of a decoction add medicine
The water of 8 times of weight of material, is decocted 1 hour, decoction is filtered out, and merges decoction liquor twice, and it is 1.05 to be concentrated into 60 DEG C of relative densities, plus second
Alcohol makes the percent by volume of alcohol content up to 75%, stirs, stands, filtering, and relative density is 1.25 when filtrate is concentrated into 65 DEG C, and
Ethanol is reclaimed, concentrate is obtained, it is refined using silica gel, selected silica gel is fitted into resin column in advance, while by the concentrate
After purified water dilution, by reverse phase silica gel post, remove the impurity in liquid, collect whole effluxes, add sucrose, be prepared into
Xuancheng's pawpaw beverage.The silica gel is 500m than surface2/ g, pore volume is 0.70ml/g, and concentrate passes through anti-phase silicon after the dilution
Glue post separation, elution, stop to water colorless is gone out.
Embodiment 2：Take Xuancheng's pawpaw 25g, lily 10g, Buddha's hand 15g, SEMEN SINAPIS ALBAE 4g, fructus amomi 10g, brush-cherry seed 20g, emblic
35g, tamarind 8g, the membrane of a chicken's gizzard 20g, the water of 10 times of weight of dosing material soak 0.5h, decoct 1 hour, and filtering, the dregs of a decoction add medicine
The water of 8 times of weight of material, is decocted 1 hour, decoction is filtered out, and merges decoction liquor twice, and it is 1.05 to be concentrated into 60 DEG C of relative densities, plus second
Alcohol makes the percent by volume of alcohol content up to 75%, stirs, stands, filtering, and relative density is 1.25 when filtrate is concentrated into 65 DEG C, and
Ethanol is reclaimed, concentrate is obtained, it is refined using silica gel, selected silica gel is fitted into resin column in advance, while by the concentrate
After purified water dilution, by reverse phase silica gel post, remove the impurity in liquid, collect whole effluxes, add sucrose, be prepared into
Xuancheng's pawpaw beverage.The silica gel is 500m than surface2/ g, pore volume is 0.70ml/g, and concentrate passes through anti-phase silicon after the dilution
Glue post separation, elution, stop to water colorless is gone out.
Embodiment 3：Take Xuancheng's pawpaw 20g, lily 15g, Buddha's hand 10g, SEMEN SINAPIS ALBAE 6g, fructus amomi 8g, brush-cherry seed 20g, emblic
30g, tamarind 10g, the membrane of a chicken's gizzard 15g, the water of 10 times of weight of dosing material soak 0.5h, decoct 1 hour, and filtering, the dregs of a decoction add medicine
The water of 8 times of weight of material, is decocted 1 hour, decoction is filtered out, and merges decoction liquor twice, and it is 1.05 to be concentrated into 60 DEG C of relative densities, plus second
Alcohol makes the percent by volume of alcohol content up to 75%, stirs, stands, filtering, and relative density is 1.25 when filtrate is concentrated into 65 DEG C, and
Ethanol is reclaimed, concentrate is obtained, it is refined using silica gel, selected silica gel is fitted into resin column in advance, while by the concentrate
After purified water dilution, by reverse phase silica gel post, remove the impurity in liquid, collect whole effluxes, add sucrose, be prepared into
Xuancheng's pawpaw beverage.The silica gel is 500m than surface2/ g, pore volume is 0.70ml/g, and concentrate passes through anti-phase silicon after the dilution
Glue post separation, elution, stop to water colorless is gone out.
Embodiment 4：The present invention improves the pharmacodynamic study of immunity
Experiment purpose：With the embodiment of the present invention 1, gavage mouse 30d, relatively more of the invention and normal group mouse is induced by ConA
Splenic lymphocyte proliferation difference, come judge the present invention whether strengthen splenic lymphocyte proliferation.
Experimental animal：Kunming mouse, male, body weight 18-22g.
Experimental procedure：Mouse, is grouped, every group 12 by body weight stratified random.Normal group gavage feeds water；Levamisole hydrochloride
Group gavage levamisole hydrochloride；The gavage 2gkg of embodiment 1-1, each group continuous gavage administration 30d.It is sterile to take spleen, according to conventional system
Into individual cells suspension, adjustment cell concentration is 5 × 105Individual/mL.Splenocyte suspension is added in 24 orifice plates, per hole 1mL,
Every animal sets two multiple holes, and a hole is normally cultivated (plus 50uL PRMI1640 nutrient solutions)；One hole adds 50uL concanavalin As
(ConA) liquid (final concentration of 4.76ug/mL).It is placed in 5%CO2, 37 DEG C of CO248h is cultivated in incubator.Experiment terminates preceding 4h, per hole
Supernatant 700uL is sucked, the PRMI1640 nutrient solutions that 700uL is free of hyclone are added, while adding 50uL 5mg/ per hole
ML MTT liquid.After culture terminates, add 1mL acid isopropyl alcohol per hole, the careful uniform crystallization to purple of piping and druming is all dissolved.Inspection
It is dispensed into before survey in 96 well culture plates, makees 4 multiple holes per hole, its OD value is determined at 570nm wavelength.
Experimental result：
The present invention to spleen lymphocyte proliferation influence (N=12)
Note：Compared with normal group★★P ＜ 0.01,★P ＜ 0.05.
Conclusion：Proliferation rate conversion values after the mouse spleen lymphocyte of the embodiment of the present invention 1 is induced by ConA are higher than normally
Group mouse, illustrates that the present invention has and improves immunity.
Claims (4)
1. a kind of Xuancheng's pawpaw beverage, it is characterised in that extracted and be prepared from by following bulk drugs weight：Xuancheng's pawpaw 15-
25g, lily 10-20g, Buddha's hand 5-15g, SEMEN SINAPIS ALBAE 4-8g, fructus amomi 6-10g, brush-cherry seed 20-25g, emblic 20-35g, tamarind
8-12g, the membrane of a chicken's gizzard 10-20g.
2. a kind of Xuancheng's pawpaw beverage according to claim 1, it is characterised in that extracted and made by following bulk drugs weight
It is standby to form：Xuancheng's pawpaw 20g, lily 15g, Buddha's hand 10g, SEMEN SINAPIS ALBAE 6g, fructus amomi 8g, brush-cherry seed 20g, emblic 30g, tamarind 10g,
The membrane of a chicken's gizzard 15g.
3. a kind of Xuancheng's pawpaw beverage according to claim 1, it is characterised in that preparation method is：Get it filled 10 times of material dosing material
The water of weight, soaks 0.5h, decocts 1 hour, and filtering, the dregs of a decoction add the water of 8 times of weight of medicinal material, decocts 1 hour, decoction filter
Go out, merge decoction liquor twice, it is 1.05 to be concentrated into 60 DEG C of relative densities, plus ethanol makes the percent by volume of alcohol content up to 75%,
Stirring, stands, filtering, and relative density is 1.25 when filtrate is concentrated into 65 DEG C, and reclaims ethanol, obtains concentrate, uses silica gel essence
Selected silica gel, is fitted into resin column by system in advance, while by after the purified water dilution of the concentrate, passing through reverse phase silica gel
Post, removes the impurity in liquid, collects whole effluxes, adds sucrose, be prepared into Xuancheng's pawpaw beverage.
4. application of the Xuancheng's pawpaw beverage in immunity food is improved according to claim 1.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107970298A (en) * | 2017-11-20 | 2018-05-01 | 宁国平衡健康管理有限公司 | A kind of Xuancheng's pawpaw ball with lipid-reducing function |
| CN108125876A (en) * | 2017-12-24 | 2018-06-08 | 宁国平衡健康管理有限公司 | A kind of Xuancheng's pawpaw mouthwash and preparation method thereof |
| CN113875918A (en) * | 2021-10-21 | 2022-01-04 | 芦永超 | Sour papaya beverage and preparation method thereof |
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| CN107970298A (en) * | 2017-11-20 | 2018-05-01 | 宁国平衡健康管理有限公司 | A kind of Xuancheng's pawpaw ball with lipid-reducing function |
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