CN107961326A - A kind of Chinese medicine composition for treating lung cancer - Google Patents
A kind of Chinese medicine composition for treating lung cancer Download PDFInfo
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- CN107961326A CN107961326A CN201610910004.2A CN201610910004A CN107961326A CN 107961326 A CN107961326 A CN 107961326A CN 201610910004 A CN201610910004 A CN 201610910004A CN 107961326 A CN107961326 A CN 107961326A
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- lung cancer
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- treating lung
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- 206010058467 Lung neoplasm malignant Diseases 0.000 title claims abstract description 16
- 201000005202 lung cancer Diseases 0.000 title claims abstract description 16
- 208000020816 lung neoplasm Diseases 0.000 title claims abstract description 16
- 239000003814 drug Substances 0.000 title claims abstract description 14
- 239000000203 mixture Substances 0.000 title claims abstract description 7
- 241000596154 Belamcanda Species 0.000 claims abstract description 5
- 244000035851 Chrysanthemum leucanthemum Species 0.000 claims abstract description 5
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 claims abstract description 5
- 235000013717 Houttuynia Nutrition 0.000 claims abstract description 5
- 240000000691 Houttuynia cordata Species 0.000 claims abstract description 5
- 240000003915 Lophatherum gracile Species 0.000 claims abstract description 5
- 240000001659 Oldenlandia diffusa Species 0.000 claims abstract description 5
- 241000237502 Ostreidae Species 0.000 claims abstract description 5
- 241001522129 Pinellia Species 0.000 claims abstract description 5
- 244000179560 Prunella vulgaris Species 0.000 claims abstract description 5
- 240000004274 Sarcandra glabra Species 0.000 claims abstract description 5
- 235000020636 oyster Nutrition 0.000 claims abstract description 5
- 235000008113 selfheal Nutrition 0.000 claims abstract description 5
- 239000000706 filtrate Substances 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims 1
- 238000002137 ultrasound extraction Methods 0.000 claims 1
- 208000024891 symptom Diseases 0.000 abstract description 10
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 9
- 208000026435 phlegm Diseases 0.000 abstract description 9
- 206010011224 Cough Diseases 0.000 abstract description 4
- 238000009472 formulation Methods 0.000 abstract description 2
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 description 7
- 210000004072 lung Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 201000011510 cancer Diseases 0.000 description 4
- 208000000059 Dyspnea Diseases 0.000 description 3
- 206010013975 Dyspnoeas Diseases 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000002685 pulmonary effect Effects 0.000 description 3
- 206010040007 Sense of oppression Diseases 0.000 description 2
- 230000008034 disappearance Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 208000013220 shortness of breath Diseases 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 208000003170 Bronchiolo-Alveolar Adenocarcinoma Diseases 0.000 description 1
- 206010058354 Bronchioloalveolar carcinoma Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 206010027458 Metastases to lung Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 241000282806 Rhinoceros Species 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000002612 cardiopulmonary effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 201000005243 lung squamous cell carcinoma Diseases 0.000 description 1
- 210000005015 mediastinal lymph node Anatomy 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000010827 pathological analysis Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/748—Oldenlandia or Hedyotis
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
- A61K36/855—Clerodendrum, e.g. glorybower
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a kind of Chinese medicine for treating lung cancer, it is made of cordate houttuynia, Glabrous Sarcandra Herb, blackberry lily, oldenlandia diffusa, the tuber of pinellia, folium isatidis, selfheal, lophatherum gracile, wild chrysanthemum and oyster.Inventive formulation uses the Chinese medicine of preventing phlegm from forming and stopping coughing, and the advantages of having to patients with lung cancer and stablize the state of an illness, improve symptom, therapeutic effect is good.
Description
Technical field
The invention mainly relates to the field of Chinese medicines, more particularly to a kind of Chinese medicine for treating lung cancer.
Background technology
Lung cancer is a kind of common pulmonary malignant tumour, its death rate has been accounted for first of cancer mortality.With patients with lung cancer
The increase of number, more and more patients proceed by chemotherapy, but in chemotherapy process, since immunity is poor or cardiopulmonary
Situations such as insufficiency, causes the generation of pulmonary infection symptom, severe patient even can because after chemotherapy pulmonary infection cause death.
The traditional Chinese medical science thinks, the generation of cancer more caused by qi and blood convulsive seizure due to phlegm-fire,《Miscellaneous diseases source stream rhinoceros is lit up》Point out, " heresy product is blocked in the heart
Air flue, gas must not lead to, and be that phlegm is blood, all pathogen conflicting with vital QI, and heresy wins, and must not just make it, inverse to form shape and have block ".Illustrate perverse trend
Lung to be attacked, is tied in the heart, impairment of dispersing and descending function of the lung, body fluid not cloth is poly- form phlegm, phlegm and qi stasis, blocks lung network, and phlegm and extravasated blood are mutually fought knot,
Lump is formed, so that into cancer.
Modern medicine mainly uses this disease the methods of operation, radiation and chemotherapy, and surgery excision is in various treatment methods
The optimal one kind of curative effect, however, about 80% lung cancer patient when making a definite diagnosis without surgical condition, operable 20%
In case, five year survival rate will also decline, and the later stage will also recur, and five year survival rate is very low.
The content of the invention
The defects of the object of the invention is exactly to make up prior art, there is provided a kind of Chinese medicine for treating lung cancer, it is to lung cancer
Patient has the advantages of stablizing the state of an illness, improving symptom.
The present invention is achieved by the following technical solutions：
A kind of Chinese medicine composition for treating lung cancer, is prepared from the following raw materials in parts by weight：60 parts of cordate houttuynia, 60 parts of Glabrous Sarcandra Herb,
60 parts of blackberry lily, 60 parts of oldenlandia diffusa, 30 parts of the tuber of pinellia, 30 parts of folium isatidis, 30 parts of selfheal, 15 parts of lophatherum gracile, 30 parts of wild chrysanthemum,
30 parts of oyster.
It is an advantage of the invention that：
Inventive formulation uses the Chinese medicine of preventing phlegm from forming and stopping coughing, the advantages of having to patients with lung cancer and stablize the state of an illness, improve symptom, treatment effect
Fruit is good.
Embodiment：
Embodiment 1
Cordate houttuynia 60g, blackberry lily 60g, oldenlandia diffusa 60g, folium isatidis 30g, selfheal 30g, wild chrysanthemum 30g, oyster 30g are taken,
Add the water of 10 times of amounts（V/W）Extracted as 100 DEG C and be concentrated into the 1/2 of original volume, filtered, obtain filtrate a；
Glabrous Sarcandra Herb 60g, tuber of pinellia 30g, lophatherum gracile 15g is taken to add 10% ethanol solution ultrasound again（500W, 40kHz）Extract 2h, mistake
Filter, is mixed into filtrate a after filtrate is volatilized solvent as 60 DEG C, continues to be kept for 60 DEG C be concentrated into the 1/5 of filtrate a original volumes, system
Must be one, a point morning and evening takes twice, and one day is one.
To prove that the present invention has the effect of fine, it is as follows to enumerate model case：
Case one：
Zhu, man, 49 years old.Leaf has a 2CM*3CM lump after patient has found to have lung in December, 2003.It is being diagnosed as lung cancer afterwards
Row resection operation afterwards, postoperative pathological show：Right lung squamous cell carcinoma.Afterwards again through multiple chemotherapy and radiation.During check in 2 months 2006
It was found that left Lung metastases.Symptoms include：It is uncomfortable in chest cough, phlegm it is few and viscous, when and hemoptysis, it is out of breath uncomfortable in chest.The red few tongue of tongue, stringy,thready and rapid pulse.Medication
30 doses of symptoms improve, original side's 50 doses of following the service of plus-minus.Clinical symptoms all disappear, and through CT examination foci disappearance, follow-up is so far.
Case two：
Lee, female, 38 years old.Patient is because feeling of oppression and pain in the chest is more than February, to hospital's CT examination：Two lung diffusivities are distributed, the granular tubercle of grain
Shape shade.By pathological diagnosis：Alveolar cell carcinoma.Through 3 courses for the treatment of of chemotherapy without positive effect.After take 20 doses of diseases of Chinese medicine of the present invention
Shape improves, original side's 50 doses of following the service of plus-minus.Clinical symptoms all disappear, and check foci disappearance through film making, follow-up is so far.
Case three：
Zhang, man, 55 years old.Patient is diagnosed as upper left lung cancer accompanied mediastinal lymph nodes because of shortness of breath uncomfortable in chest three months to hospital's CT examination
Transfer.By 3 course for the treatment of aggravations of chemotherapy.Symptoms include：Feeling of oppression and pain in the chest, dyspnea with shortness of breath, cough phlegm is thin, blood-stained sputum, and complexion is grey
In vain, purplish tongue has ecchymosis, thready and hesitant pulse.Clothes 20 doses of symptoms of Chinese medicine of the present invention are clearly better, original side's 50 doses of following the service of plus-minus.Clinical condition
Shape disappears substantially, and lesion range shorter is checked through film making.Regular further consultation, follow-up is so far.
Claims (2)
1. a kind of Chinese medicine composition for treating lung cancer, it is characterised in that be prepared from the following raw materials in parts by weight：60 parts of cordate houttuynia,
60 parts of Glabrous Sarcandra Herb, 60 parts of blackberry lily, 60 parts of oldenlandia diffusa, 30 parts of the tuber of pinellia, 30 parts of folium isatidis, 30 parts of selfheal, 15 parts of lophatherum gracile,
30 parts of wild chrysanthemum, 30 parts of oyster.
2. a kind of Chinese medicine composition for treating lung cancer according to claim 1, its feature are comprising the following steps：
1）Cordate houttuynia, blackberry lily, oldenlandia diffusa, folium isatidis, selfheal, wild chrysanthemum, oyster are taken in proportion, add the water of 10 times of amounts
Extracted as 100 DEG C and be concentrated into the 1/2 of original volume, filtered, obtain filtrate a；
2）Glabrous Sarcandra Herb, the tuber of pinellia, lophatherum gracile is taken to add 10% ethanol solution ultrasonic extraction 2h again, filtering, filtrate is volatilized as 60 DEG C
It is mixed into after solvent in filtrate a, continues 60 DEG C of holding and be concentrated into the 1/5 of filtrate a original volumes, be made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610910004.2A CN107961326A (en) | 2016-10-19 | 2016-10-19 | A kind of Chinese medicine composition for treating lung cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610910004.2A CN107961326A (en) | 2016-10-19 | 2016-10-19 | A kind of Chinese medicine composition for treating lung cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107961326A true CN107961326A (en) | 2018-04-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610910004.2A Pending CN107961326A (en) | 2016-10-19 | 2016-10-19 | A kind of Chinese medicine composition for treating lung cancer |
Country Status (1)
| Country | Link |
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| CN (1) | CN107961326A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101879257A (en) * | 2009-05-08 | 2010-11-10 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating tumors |
| CN103041291A (en) * | 2012-11-29 | 2013-04-17 | 宁国市中医肿瘤医院 | Traditional Chinese medicine for treating lung cancer |
-
2016
- 2016-10-19 CN CN201610910004.2A patent/CN107961326A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101879257A (en) * | 2009-05-08 | 2010-11-10 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating tumors |
| CN103041291A (en) * | 2012-11-29 | 2013-04-17 | 宁国市中医肿瘤医院 | Traditional Chinese medicine for treating lung cancer |
Non-Patent Citations (1)
| Title |
|---|
| 孙建立等: "中医辨证结合吉非替尼治疗晚期非小细胞肺癌临床疗效及证候变化分析", 《四川中医》 * |
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