CN103169746A - Traditional Chinese medicine composition for treating lung cancer - Google Patents
Traditional Chinese medicine composition for treating lung cancer Download PDFInfo
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- CN103169746A CN103169746A CN2013100918644A CN201310091864A CN103169746A CN 103169746 A CN103169746 A CN 103169746A CN 2013100918644 A CN2013100918644 A CN 2013100918644A CN 201310091864 A CN201310091864 A CN 201310091864A CN 103169746 A CN103169746 A CN 103169746A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating lung cancer and belongs to the field of the traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the raw materials pseudo-ginseng, American ginseng and cordyceps sinensis in a certain ratio, and has obvious therapeutic effect on the lung cancer at different development stages.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition that is used for the treatment of pulmonary carcinoma, belong to the field of Chinese medicines.
Background technology
At primary bronchogenic carcinoma of lung, be called for short pulmonary carcinoma, refer to a kind of malignant tumor of the unrestricted hypertrophy of epidermis cell of alveolar wall, bronchus or bronchioles mucosa, belong to the categories such as the traditional Chinese medical science " lump in the right hypochondrium ", " lung rock ", " lump at the right hypochondrium ".Worldwide, accounted for because of 28% of cancer mortality total number of persons by the lung cancer death person, occupy the first.5 years survival rates of suffering from pulmonary carcinoma person are up to 15%.Medical measure now still is difficult to pulmonary carcinoma is carried out early diagnosis, most of patient seek medical advice or when making a definite diagnosis to middle and advanced stage, this has caused very large difficulty for treatment of pulmonary carcinoma.Operative treatment is suitable for occurring in the following nonsmall-cell lung cancer of III A level (NSCLC) of a side, and can reach 4.4% because of the operation of lung cancer died.Most of patient can only accept radiotherapy or chemotherapy, but its toxic action is larger, easily causes bone marrow depression and hypoimmunity.Use in recent years target therapy, more traditional embolic chemotherapy has some advantage, but to advanced lung cancer still unsatisfactory curative effect.Clinical control over nearly more than 20 years studies confirm that, oral Chinese medicine can be applicable to the treatment of advanced lung cancer, has Synergistic or Attenuation if unite with chemicotherapy.
The traditional Chinese medical science thinks that the pathogenic factor of pulmonary carcinoma is mainly healthy energy virtual loss and stagnation of QI-blood.Chinese medicine takes much count of the effect of healthy energy in morbidity, thinks that function is normal, YIN and YANG in a relative equilibrium, and QI and blood is vigorous, defends outer solid closely, and pathogenic factor is difficult to invade, and disease has no way of occuring.Healthy energy interior-deficiency, internal organs yin and yang qi and blood disorder are the ill main foundations of pulmonary carcinoma.Old, chronic Pulmonary Diseases, the lung qi consume is not enough; Or internal injury caused by excess of seven emotions, the QI rising in reverse order stagnation of QI, ascending or descending movement of vital Qi imbalance; Or overwork; Or eating and drinking without temperance or unclean, pica, transporting and transforming function of the spleen and stomach mistake department causes the cloudy loss of lung qi, the lifting imbalance, exopathogen is taken advantage of a weak point, and exopathogen is detained and is not gone, and functional activity of QI being not smooth causes pulmonary's blood stasis of blood stagnant eventually, and is of a specified duration and become long-pending piece.In addition, stagnation of QI-blood is a very important link in the genesis of tumor.Evil poison invasion and attack cause the stagnation of QI and do not declare, and then blood stasis are not all right.The unable easy stagnation of QI of deficiency of vital energy operation, but the stagnation of QI hyperamization stasis of blood, and Yin and fluid deficiency, blood is slow, but the also hyperamization stasis of blood, blood stasis with the passing of time, long-pending piece gradually becomes.The principal character of malignant tumor is lump, tangiblely levy, hardly do not move, and belongs to the syndrome of blood stasis category of the traditional Chinese medical science.Modern medicine study shows, Abnormal Blood Rheology is ubiquitous a kind of pathological change in tumor patient, and viscosity of blood is higher, and the tumor blood stasis is more obvious, that blood is in is glutinous, poly-state, and the existence of the blood high viscosity syndrome impact important on being formed with of tumor.
In a word, pulmonary carcinoma is because healthy energy is deficient, yin and yang imbalance, and evil poison is taken advantage of a weak point in opponent's defence into lung, and is evil stagnant in lung, causes the lungs functional disorder, and lung qi Fen is strongly fragrant, and mistake department falls in a surname, disorder of QI movement, blood is obstructed, and the stasis blocking venation so ecchymosis is cementing, with the passing of time forms pulmonary and amasss piece.Therefore, pulmonary carcinoma is that a kind of whole body belongs to void, local true disease, and characteristic of disease belongs to deficiency in origin and excess in superficiality.The void of pulmonary carcinoma is take deficiency of both QI and YIN as common, actually nothing more than the stagnation of QI, blood stasis, solidifying, the malicious poly-pathological change of expectorant.
Summary of the invention
In the pathogeny for pulmonary carcinoma, the inventor provides a kind of Chinese medicine composition, is used for the treatment of pulmonary carcinoma.This Chinese medicine composition is comprised of the crude drug of following part by weight: Radix Notoginseng 40-80 part, Radix Panacis Quinquefolii 8-12 part, Cordyceps 8-12 part.
Preferably, the ratio of above-mentioned raw materials medicine is: Radix Notoginseng 50-70 part, Radix Panacis Quinquefolii 9-11 part, Cordyceps 9-11 part.
Optimum, the ratio of above-mentioned raw materials medicine is: 60 parts of Radix Notoginseng, 10 parts of Radix Panacis Quinquefoliis, 10 parts of Cordyceps.
Theory of Chinese medical science is analyzed: Radix Notoginseng also claims clear ginseng, Herba Wedeliae Wallichii, Panax pseudoginseng, Typhonium flagelliforme (Lodd.) Blume, Radix Notoginseng etc. at ancient times, and the flat sweet-bitter flavor of its property enters liver, stomach, large intestine channel, has eliminating blood stasis and smoothing collaterals, nourishing blood and promoting blood circulation, the effect of pain relieving eliminating stagnation, eliminating evil and just do not hinder, be described as " treating blood disorders quality goods ", blood stasis is secretly disappeared in invisible, " hemostasis and without staying the fraud of the stasis of blood, invigorate blood circulation and without hemorrhage anxiety ", can the promoting blood circulation and hemostasis analgesic therapy and stronger tonic effect is arranged, therefore we are with thinking monarch drug; Radix Panacis Quinquefolii has another name called Radix Panacis Quinquefolii, its sweet in the mouth cool in nature, and little hardship, cool, GUIXIN lung kidney three warps have the effect of tonifying QI to produce body fluid, " rich gas is thin, the tonifying the lung pathogenic fire reducing, and born fluid, relieving restlessness is tired, and is empty and have the fiery person suitable ", we are with thinking ministerial drug; Cordyceps, sweet in the mouth, warm in nature enters lung, kidney channel, can invigorating the lung and the kidney, hemostasis and phlegm, can " secret lean gas be specially mended the gate of vitality ", be used for " protecting the lung kidney tonifying, hemostasis and phlegm, chronic cough ", be to be adjuvant drug.Above-mentioned three medicines share, and gather altogether promoting blood circulation to remove obstruction in the collateral, and the effect of supplementing QI and nourishing YIN is exclusively used in the disease of " empty, the stasis of blood " for the treatment of pulmonary carcinoma.
Because three kinds of crude drug of this Chinese medicine composition are all comparatively famous and precious and effect is stronger, thus according to tradition all former powder be used as medicine, that is: get Radix Notoginseng, Radix Panacis Quinquefolii and Cordyceps, be mixed in proportion pulverization, cross 100 mesh sieves, drying, get powder or directly dress up capsule or be pressed into tablet, orally using.In special administration situation, as when injection, use after also three kinds of crude drug can being done refinement treatment, effective component extracting.
Chinese medicine composition of the present invention inventor place hospital oncology as institute in preparation use, the pulmonary carcinoma that is used for the treatment of different stages of development, or use separately or be used in conjunction with chemicotherapy, can significantly improve patients ' life quality, extend life span, its total effective rate can reach more than 80%.Below by nearest model case, using method and the effect of Chinese medicine composition of the present invention are described.
The specific embodiment
Embodiment 1:
The state of an illness: Zhao, man, 80 years old.On June 28th, 2007, the patient found the superior lobe of right lung peripheral type carcinoma of lung because of heating, the row breast CT of coughing, and shifted in tumor size 2.9 * 2.6cm, lung, and disease belongs to the IV phase.Be shown as adenocarcinoma in Beijing Tumour Hospital's row Transthoracic Biopsy pathology the same year by the end of July.The patient refuses the western medical treatment means such as chemicotherapy, requires Chinese traditional treatment, in JIUYUE in 2007 first visit on the 29th.Inscribe disease opinion: cough, cough white expectorant, xerostomia, weak, deficiency of QI with disinclination to talk, receive can, two just transfer, sleep can.Dark tongue quality, white and thin fur, stringy and thready pulse.Dialectical genus deficiency of both QI and YIN, blood-stasis internal-depression is controlled with supplementing QI and nourishing YIN blood circulation promoting and blood stasis dispelling.
Treatment: give the powder (get 60 parts of Radix Notoginseng, 10 parts of Radix Panacis Quinquefoliis, 10 parts of Cordyceps, mix pulverization, drying, and get final product) of Chinese medicine composition of the present invention, every day sooner or later on an empty stomach boiled water take, each amount is 1 gram, 30 days is 1 course for the treatment of.
Effect: after 2 weeks of taking medicine, above-mentioned all diseases are improved.Patient's spirit is good, and is full of confidence.Continuing again took for 2 weeks, cough, expectoration, and all diseases such as xerostomia are clearly better, and muscle power increases.Advise patient's long-term taking.Patients ' life quality be improved significantly, the tumor body increasess slowly, on August 19th, 2010 check breast CT shows superior lobe of right lung lump size 4.5 * 3.8cm.Follow up a case by regular visits to (2012-12-26) so far, patient is still survived, stable disease.
Embodiment 2:
The state of an illness: Lee, man, 52 years old.On August 26th, 2009 looked into breast CT and shows lower-left lung occupy-place because of cough, sputum mixed with blood, size 4.4 * 3.2cm, mediastinal lymph node metastasis.JIUYUE 4th in 305 hospital's row bronchoscope biopsy pathology was in 2009: low differentiated squamous-cell carcinomas.The sick genus III phase, can't perform the operation.Because the refusal chemicotherapy is sought Chinese medicine, in JIUYUE in 2009 first visit on the 14th.Inscribe disease opinion: cough, expectoration, sputum mixed with blood, uncomfortable in chest, breathe hard, weak, receive can, double knee joint, the hip arthralgia, two just transfer, dormancy can.Pale tongue is dark, yellow and thin fur, stringy pulse.Dialectical genus deficiency of both QI and YIN, blood-stasis internal-depression is controlled with supplementing QI and nourishing YIN blood circulation promoting and blood stasis dispelling.
Treatment: with embodiment 1.
Effect: take medicine after 1 week, cough and expectoration alleviates, and spitting of blood is stopped, and muscle power takes a turn for the better, and pain only.Continuing again took for 2 weeks, and cough, expectoration obviously alleviate, and sensation of oppression over the chest with shortness of breath is alleviated, and without weak, the food of receiving increases, and body weight increases.Patient's spirit is good, and is full of confidence, advises patient's long-term taking.Quality of life improves, and the tumor body increasess slowly, and check on April 15th, 2010 breast CT shows lower-left lung lump size 5.6 * 5.1cm.Learn this patient in death in May, 2011 through following up a case by regular visits to, survived nearly 2 years.
Embodiment 3:
The state of an illness: Wang, man, 87 years old.In JIUYUE, 2006 is looked into breast CT in the Beijing University the People's Hospital and is shown: inferior lobe of left lung occupy-place, big or small approximately 2.1*2.8cm, vertical phrenic lymph nodes enlargement.Further be thought of as in the capable PET-CT of air force general hospital: lower-left lung peripheral type carcinoma of lung, companion's hilus pulumonis, vertical phrenic lymph nodes shift.Tumour hospital of medical courses in general institute expectorant looks for cancerous cell to find adenocarcinoma cell, and clarifying a diagnosis is the lower-left adenocarcinoma of lung, and TNM belongs to the III phase by stages.Start from the capable left lung lump Gamma knife treatment of air force general hospital 10 times in October, 2006, show in air force general hospital check breast CT in November, 2006: the inferior lobe of left lung cancer, size is about 1*1.69cm, vertical phrenic lymph nodes enlargement.For asking Chinese medicine, first visit on November 20 in 2006.Inscribe disease opinion: even have dry cough, and slightly xerostomia is weak, receive can, two just transfer, dormancy can.Light red tongue is dark, white and thin fur, deep-slow pulse.Dialectical genus deficiency of both QI and YIN, blood-stasis internal-depression is controlled with supplementing QI and nourishing YIN blood circulation promoting and blood stasis dispelling.
Treatment: with embodiment 1.
Effect: after 2 weeks of taking medicine, cough stops, and muscle power increases, and is movable as usual, do not tell significant discomfort, advises patient's long-term taking.Show that in air force general hospital check breast CT pulmonary masses disappears in January, 2007.The patient is full of confidence, adheres to long-term taking pharmaceutical composition of the present invention, and without the significant discomfort symptom, quality of life is higher.Patient's periodic review breast CT has no significant change, and focus is stable, and quality of life is high.Follow up a case by regular visits to so far the patient and still survive, the idiopathy was survived approximately more than 6 years.
Embodiment 4:
The state of an illness: Wang, man, 60 years old.The patient looks into breast CT because coughing to 301 Hospital in June, 2012 and shows: the superior lobe of right lung peripheral type carcinoma of lung, the vertical phrenic lymph nodes of companion's hilus pulumonis shifts.Further aspiration biopsy pathology shows: poorly differentiated adenocarcinoma.TNM belongs to the III phase by stages.The patient refuses chemicotherapy because suffering from coronary heart disease, and disease opinion is inscribed in first visit on July 4 in 2012: cough, expectoration, the expectorant white matter is glutinous, breathe hard, xerostomia, receive can, urine is many, stool can, sleep poor.Tongue is dark red, and tongue is few, stringy and thready pulse.Card belongs to deficiency of both QI and YIN, and blood-stasis internal-depression is controlled with supplementing QI and nourishing YIN blood circulation promoting and blood stasis dispelling.
Treatment: with embodiment 1.
Effect: after 2 weeks of taking medicine, cough and expectoration is stopped, the improvement of breathing hard, and xerostomia disappears, and advises the patient to adhere to taking.Check breast CT prompting pulmonary masses in October, 2012 ditto similar, the patient firms confidence more, advises and continues to take Chinese medicine composition of the present invention, check breast CT prompting pulmonary masses in January, 2013 still ditto similar, the tumor body is stable, and quality of life is better, and the idiopathy is survived July.
Claims (5)
1. Chinese medicine composition that is used for the treatment of pulmonary carcinoma is characterized in that what this Chinese medicine composition was comprised of the crude drug of following part by weight: Radix Notoginseng 40-80 part, Radix Panacis Quinquefolii 8-12 part, Cordyceps 8-12 part.
2. Chinese medicine composition according to claim 1, is characterized in that the ratio of each crude drug is: Radix Notoginseng 50-70 part, Radix Panacis Quinquefolii 9-11 part, Cordyceps 9-11 part.
3. Chinese medicine composition according to claim 1, is characterized in that the ratio of each crude drug is: 60 parts of Radix Notoginseng, 10 parts of Radix Panacis Quinquefoliis, 10 parts of Cordyceps.
4. the preparation method of claim 1,2 or 3 described Chinese medicine compositions is characterized in that the method is: get Radix Notoginseng, Radix Panacis Quinquefolii and Cordyceps, be mixed in proportion pulverization, cross 100 mesh sieves, drying gets powder or dresses up capsule or be pressed into sheet.
5. claim 1,2 or 3 described Chinese medicine compositions are for the preparation of the application in the medicine for the treatment of pulmonary carcinoma.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106138791A (en) * | 2015-04-01 | 2016-11-23 | 李湘 | A kind of Chinese medicine composition treating pulmonary carcinoma and preparation method thereof |
| CN110420268A (en) * | 2019-09-09 | 2019-11-08 | 张伟华 | A kind of Chinese patent drug assisting in the treatment of lump, cancer |
| CN116350674A (en) * | 2023-02-08 | 2023-06-30 | 中国中医科学院广安门医院 | Traditional Chinese medicine composition for preventing early lung metastasis of Lewis lung cancer and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1178110A (en) * | 1996-09-28 | 1998-04-08 | 熊学贤 | Medicine for lung cancer |
| CN102960715A (en) * | 2012-09-07 | 2013-03-13 | 无锡市天赐康生物科技有限公司 | Immunity-enhancing and hypoxia tolerant health food and preparation method thereof |
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- 2013-03-21 CN CN201310091864.4A patent/CN103169746B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1178110A (en) * | 1996-09-28 | 1998-04-08 | 熊学贤 | Medicine for lung cancer |
| CN102960715A (en) * | 2012-09-07 | 2013-03-13 | 无锡市天赐康生物科技有限公司 | Immunity-enhancing and hypoxia tolerant health food and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106138791A (en) * | 2015-04-01 | 2016-11-23 | 李湘 | A kind of Chinese medicine composition treating pulmonary carcinoma and preparation method thereof |
| CN110420268A (en) * | 2019-09-09 | 2019-11-08 | 张伟华 | A kind of Chinese patent drug assisting in the treatment of lump, cancer |
| CN116350674A (en) * | 2023-02-08 | 2023-06-30 | 中国中医科学院广安门医院 | Traditional Chinese medicine composition for preventing early lung metastasis of Lewis lung cancer and application thereof |
| CN116350674B (en) * | 2023-02-08 | 2024-02-13 | 中国中医科学院广安门医院 | Traditional Chinese medicine composition for preventing early lung metastasis of Lewis lung cancer and application thereof |
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