CN103610966A - Medicament for treating anaphylactoid purpura and producing method thereof - Google Patents

Abstract

The invention discloses a medicament for treating anaphylactoid purpura and a producing method thereof and relates to the fields of traditional Chinese medicine preparations and preparation methods thereof. The medicament is prepared from the following raw material components in parts by weight: 3 parts of rhinoceros horn, 10 parts of silver flower, 10 parts of fructus forsythiae, 12 parts of cicada slough, 12 parts of purple gromwell, 15 parts of radix rubiae, 13 parts of radix rehmanniae, 15 parts of cortex moutan, 20 parts of salvia miltiorrhiza, 30 parts of reed rhizome, 10 parts of licorice, 5 parts of Chinese angelica, 7 parts of dangshen, 3 parts of rhizoma atractylodis macrocephalae, 5 parts of arillus longan and 5 parts of poria with hostwood. The invention provides the medicament for treating anaphylactoid purpura and the producing method thereof; the compatibility of medicines is reasonable, the treatment effect is obvious, the medicament can be prepared into a tablet, not only can the tablet be conveniently taken, but also the treatment effect of the tablet is much better than that of traditional Chinese medicine soup which is directly taken.

Description

Medicament and the production method thereof for the treatment of anaphylactoid purpura

Technical field:

The present invention relates to Chinese medicine preparation and pharmaceutical methods field, relate in particular to a kind of medicament and production method thereof for the treatment of anaphylactoid purpura.

Background technology:

Anaphylactoid purpura is a kind of blood capillary allergy pathological changes, is modal hemorrhage in vascular purpura, is usual diseases of childhood, is more common in teenager.At present, the existing medicine that is used for the treatment of anaphylactoid purpura has a lot, but mostly is Chinese medicine composition, takes inconvenience, and medicining cycle is long, takes effect slow, and effect is not very desirable.

Summary of the invention:

The object of this invention is to provide a kind of medicament and production method thereof for the treatment of anaphylactoid purpura, to solve the problems of the technologies described above.

Technical problem to be solved by this invention realizes by the following technical solutions.

A kind of medicament and production method thereof for the treatment of anaphylactoid purpura, it is characterized in that, each raw material components and group component are: 3 parts of Cornu rhinocerotiss, 10 parts of Flos Lonicerae, 10 parts of Fructus Forsythiaes, 12 parts of Periostracum Cicadaes, 12 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts, Radix Rubiae, 13 parts, the Radix Rehmanniae, 15 parts of Cortex Moutans, 20 parts of Radix Salviae Miltiorrhizaes, 30 parts of Rhizoma Phragmitiss, 10 parts, Radix Glycyrrhizae, 5 parts of Radix Angelicae Sinensis, 7 parts of Radix Codonopsis, 3 parts of the Rhizoma Atractylodis Macrocephalaes, dragon are with 5 parts of meat, 5 parts of Poria cum Radix Pinis.

A kind of production method for the treatment of the medicament of anaphylactoid purpura, it is characterized in that, comprise the step that each raw material components is ground to form to medicated powder, after 3 parts of Cornu rhinocerotiss, 10 parts of Flos Lonicerae, 10 parts of Fructus Forsythiaes, 12 parts of Periostracum Cicadaes, 12 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts, Radix Rubiae, 13 parts, the Radix Rehmanniae, 15 parts of Cortex Moutans, 20 parts of Radix Salviae Miltiorrhizaes, 30 parts of Rhizoma Phragmitiss, 10 parts, Radix Glycyrrhizae, 5 parts of Radix Angelicae Sinensis, 7 parts of Radix Codonopsis, 3 parts of the Rhizoma Atractylodis Macrocephalaes, dragon are mixed in proportion with 5 parts of 5 parts of meat, Poria cum Radix Pini, grind to form powdery;

By the medicated powder grinding to form, as for pressurize in high-pressure steam more than 2 hours, then aeration, takes out medicated powder and makes tablet.The harder cutin in medicated powder can be fully softened in steam pressurize, active ingredient is separated out, to improve drug effect.

Prescription of the present invention also can adjust, to prepare the pharmaceutical preparation for the purpura patient with different symptoms.

For with the abdomen pain person of having blood in stool, add the Radix Paeoniae Alba, Rhizoma Corydalis, Fructus Aurantii, charred Radix Sanguisorbae;

For with the Wan of the joint Yong Zhe，Jia Qin, Radix Saposhnikoviae;

For with nose bleeding from the gum blood, add Fructus Gardeniae, charred Nodus Nelumbinis Rhizomatis;

For with hematuria person, increasing, Herba Cirsii, Rhizoma Imperatae;

For itching with skin flea, add Herba Schizonepetae, Cortex Dictamni, the Fructus Kochiae, reuse Periostracum Cicadae;

For with vomiter, add Caulis Bambusae In Taenia;

For not disappearing with injury of kidney urine protein, edema person, add Herba Leonuri, Rhizoma Dioscoreae, Rhizoma Alismatis. Semen Plantaginis, Semen Coicis.

During treatment, quit smoking, spill, meat or fish, pungent, process the foods such as Bo.

Beneficial effect of the present invention is:

The invention provides a kind of medicament and production method thereof for the treatment of anaphylactoid purpura, compatibility of drugs is reasonable, evident in efficacy, and this medicine is made tablet, and the therapeutic effect of not only taking convenience, and medicine is also than good many of direct decoction Chinese medicine decoction.

The specific embodiment:

For technological means, creation characteristic that the present invention is realized, reach object and effect is easy to understand, below in conjunction with specific embodiment, further set forth the present invention.

Embodiment 1

Treat a medicament for anaphylactoid purpura, the raw material Chinese medicinal components of employing is: Cornu rhinocerotis 3g, Flos Lonicerae 10g, Fructus Forsythiae 10g, Periostracum Cicadae 12g, Radix Arnebiae (Radix Lithospermi) 12g, Radix Rubiae 15g, Radix Rehmanniae 13g, Cortex Moutan 15g, Radix Salviae Miltiorrhizae 20g, Rhizoma Phragmitis 30g, 10 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 5g, Radix Codonopsis 7g, Rhizoma Atractylodis Macrocephalae 3g, dragon are with meat 5g, Poria cum Radix Pini 5g.

Each raw material components of group component is ground to form to medicated powder, and by the medicated powder grinding to form, as for pressurize in high-pressure steam more than 2 hours, then aeration, takes out medicated powder and makes tablet.

This organizes 60 examples, male 37 examples, female's 23 examples: age 6～38,3 days～l of the course of disease 6 months, simple skin purpura person 24 examples, abdomen type 13 examples, joint type 8 examples, kidney type 6 examples, mixed type 19 examples.Wherein 24 examples have obvious infection inducement.Urine microscopy abnormal change person 18 examples, fecal occult blood 19 examples, erythrocyte sedimentation rate speedup and anti-" O " increase 28 examples, and platelet count is all normal.

Result: (purpura is disappeared in 51 example healings, other transference cures, laboratory examination are normal, drug withdrawal not recurrence in 3 months), 6 examples are effective (after purpura disappears, occasionally there is recurrence), 2 examples are effectively (through treatment in 2 months, within 3 months, again recur l time), 1 example invalid (through treatment half a year, clinical symptoms is improved slowly).Total effective rate 98.3%.Generally take medicine 4 doses, administration time is the shortest 6 days, the longest by 42, average 18.5 days.The improvement time: purpura is disappeared average about 8 days, joint carbuncle disappears average about 6 days; Average about 4 days of stomachache silk ribbon attached to an official seal or a medal solution.During medication, there is not any side effect.

Model case: female, 10 years old.First visit on April 2 in 1986.Main suit: fever with aversion to cold before 3 days, nasal obstruction watery nasal discharge, pharyngeal swollen pain,, then there is ecchymosis and go to a doctor in arthralgia.Examine quarter: extremity, and trunk skill skin speckle emerges in large numbers in batch, and common with extremity, speckle is purplish red, and that presses is colour-fast, and joint is wandering pain, and abdomen pain battle array is done, pharyngeal congestion tonsil Io enlargement, red tongue, white and thin fur, floating and rapid pulse.38.8 ℃ of body temperature, 114 beats/min, pulse, breathes 28 time, minutes, blood pressure 13/8kpa.Chemical examination: leukocyte, erythrocyte, platelet and go out, clotting time is all in normal range, is diagnosed as anaphylactoid purpura.Control suitable wind and heat dispersing, cool each large removing toxic substances, declares ecchymosis.The Fang Ni purpura Tonga Radix Paeoniae Alba, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Fructus Aurantii.Take medicine 3 doses.Infant slightly sweating, heating is moved back, and stomachache subtracts, and it is light that purpura turns.The own bone joints-most important juncture of medicine, goes on 3 doses, and purpura is suddenly enlightened disappears, and remaining disease knowing removed.Follow up a case by regular visits to not recurrence in 3 months.

Anaphylactoid purpura belongs to blood disorder category, " hematohidrosis " recorded in the classic doctor of traditional Chinese medical science mat, " speckle poison ", " macule ", and diseases such as " hemorrhagic disease with purpuras " and primary disease have similarity.As < < Ling Shu Miraculous Pivot or Divine Axis speckle viral disease is waited > > cloud: " disease of speckle poison, is that steam enters stomach, and the main muscle of stomach; its heat is held poison under the arm and accumulate and amass in stomach, and poison is smoked to be sent out in muscle, and shape flea stings and stings; red speckle rises, and all circles are all over body." < < Yizong Jinjian surgery heart method > > hemorrhagic disease with purpura cloud: " and more than this card, because of baby, experience the gas of strict epidemic disease, strongly fragrant in skin, condense and form.Large and small table purpura point, if color shape Fructus Vitis viniferae.Send out in all over, only lower limb shin is in the majority." < < Elementary Medicine flesh blood nosebleed > > cloud: " blood is from the pore person of going out, the hematohidrosis of meaning." the above cause of disease of having sketched purpura, sick maple and symptom.The author thinks that its pathomechanism is the absurd row of pathogenic heat forcing blood, QI and blood fight knot, the venation of burning, and causes each large extravasation of blood, and wandering skin flesh overflows in arteries and veins outside and a speckle.It is hot more anxious that primary disease comes, and purpura occurs in batches, rises one after another, change unpredictably, and outbreak repeatedly, more, in side, Cornu rhinocerotis is salty-cold for touching difficulty, and be equipped with Radix Arnebiae (Radix Lithospermi), alizarinly draw, the Radix Rehmanniae, Cortex Moutan, Rhizoma Phragmitis clearing away heat and cooling blood scattered silt, in case blood and accumulation of heat, also for making medicine.All medicines are instrumental ensembled wind and heat dispersing, and removing heat from bloodization is become silted up, and declares strongly fragrant letting out skin rashes completely, make blood circulating out of vessels accelerate to dissipate, and all illness are alleviated thereupon.This side's medication, compatibility is proper, and Gu Er effect is got very prompt.

More than show and described ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; that in above-described embodiment and description, describes just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.The claimed scope of the present invention is defined by appending claims and equivalent thereof.

Claims (2)

1. a medicament for the treatment of anaphylactoid purpura, it is characterized in that, each raw material components and group component are: 3 parts of Cornu rhinocerotiss, 10 parts of Flos Lonicerae, 10 parts of Fructus Forsythiaes, 12 parts of Periostracum Cicadaes, 12 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts, Radix Rubiae, 13 parts, the Radix Rehmanniae, 15 parts of Cortex Moutans, 20 parts of Radix Salviae Miltiorrhizaes, 30 parts of Rhizoma Phragmitiss, 10 parts, Radix Glycyrrhizae, 5 parts of Radix Angelicae Sinensis, 7 parts of Radix Codonopsis, 3 parts of the Rhizoma Atractylodis Macrocephalaes, dragon are with 5 parts of meat, 5 parts of Poria cum Radix Pinis.

2. described in a claim 1, treat the production method of the medicament of anaphylactoid purpura, it is characterized in that, comprise the step that each raw material components is ground to form to medicated powder, after 3 parts of Cornu rhinocerotiss, 10 parts of Flos Lonicerae, 10 parts of Fructus Forsythiaes, 12 parts of Periostracum Cicadaes, 12 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts, Radix Rubiae, 13 parts, the Radix Rehmanniae, 15 parts of Cortex Moutans, 20 parts of Radix Salviae Miltiorrhizaes, 30 parts of Rhizoma Phragmitiss, 10 parts, Radix Glycyrrhizae, 5 parts of Radix Angelicae Sinensis, 7 parts of Radix Codonopsis, 3 parts of the Rhizoma Atractylodis Macrocephalaes, dragon are mixed in proportion with 5 parts of 5 parts of meat, Poria cum Radix Pini, grind to form powdery;

By the medicated powder grinding to form, as for pressurize in high-pressure steam more than 2 hours, then aeration, takes out medicated powder and makes tablet.