CN107927643A - A kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis - Google Patents
A kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis Download PDFInfo
- Publication number
- CN107927643A CN107927643A CN201711154292.4A CN201711154292A CN107927643A CN 107927643 A CN107927643 A CN 107927643A CN 201711154292 A CN201711154292 A CN 201711154292A CN 107927643 A CN107927643 A CN 107927643A
- Authority
- CN
- China
- Prior art keywords
- parts
- xuancheng
- pawpaw
- meal replacement
- osteoporosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 244000189799 Asimina triloba Species 0.000 title claims abstract description 45
- 235000006264 Asimina triloba Nutrition 0.000 title claims abstract description 45
- 235000009467 Carica papaya Nutrition 0.000 title claims abstract description 45
- 235000012054 meals Nutrition 0.000 title claims abstract description 31
- 208000001132 Osteoporosis Diseases 0.000 title claims abstract description 29
- 239000000843 powder Substances 0.000 title claims abstract description 29
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 12
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 12
- 244000046146 Pueraria lobata Species 0.000 claims abstract description 11
- 235000010575 Pueraria lobata Nutrition 0.000 claims abstract description 11
- 240000007126 Citrus medica var. sarcodactylis Species 0.000 claims abstract description 10
- 230000037182 bone density Effects 0.000 claims abstract description 10
- 210000000582 semen Anatomy 0.000 claims abstract description 10
- 239000003814 drug Substances 0.000 claims abstract description 9
- 230000036541 health Effects 0.000 claims abstract description 8
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 238000000605 extraction Methods 0.000 claims abstract description 5
- 239000004480 active ingredient Substances 0.000 claims abstract description 4
- 238000002360 preparation method Methods 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 6
- 238000012856 packing Methods 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 3
- 238000009472 formulation Methods 0.000 claims description 2
- 230000006872 improvement Effects 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 210000000988 bone and bone Anatomy 0.000 description 9
- 208000002193 Pain Diseases 0.000 description 8
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 238000011161 development Methods 0.000 description 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- 208000010392 Bone Fractures Diseases 0.000 description 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 4
- 206010017076 Fracture Diseases 0.000 description 4
- 241000700159 Rattus Species 0.000 description 4
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 229910052791 calcium Inorganic materials 0.000 description 4
- 210000003414 extremity Anatomy 0.000 description 4
- 229960001727 tretinoin Drugs 0.000 description 4
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 description 3
- JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 description 3
- YBRJHZPWOMJYKQ-UHFFFAOYSA-N Oleanolic acid Natural products CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C1)C(=O)O YBRJHZPWOMJYKQ-UHFFFAOYSA-N 0.000 description 3
- MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000004438 eyesight Effects 0.000 description 3
- 238000003304 gavage Methods 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 229940100243 oleanolic acid Drugs 0.000 description 3
- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 description 3
- 210000000689 upper leg Anatomy 0.000 description 3
- 240000005528 Arctium lappa Species 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 241000700157 Rattus norvegicus Species 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 235000021374 legumes Nutrition 0.000 description 2
- 210000002540 macrophage Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000001603 reducing effect Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- 241000572565 Alpinia oxyphylla Species 0.000 description 1
- 235000003130 Arctium lappa Nutrition 0.000 description 1
- 235000008078 Arctium minus Nutrition 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 208000020084 Bone disease Diseases 0.000 description 1
- 206010006002 Bone pain Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 244000201986 Cassia tora Species 0.000 description 1
- 235000014552 Cassia tora Nutrition 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 206010010214 Compression fracture Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010018612 Gonorrhoea Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 240000006859 Jasminum officinale Species 0.000 description 1
- 235000010254 Jasminum officinale Nutrition 0.000 description 1
- 241000366676 Justicia pectoralis Species 0.000 description 1
- 208000030136 Marchiafava-Bignami Disease Diseases 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 208000029725 Metabolic bone disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 102000003425 Tyrosinase Human genes 0.000 description 1
- 108060008724 Tyrosinase Proteins 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 238000009412 basement excavation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000021022 fresh fruits Nutrition 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 210000000527 greater trochanter Anatomy 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 201000010727 rectal prolapse Diseases 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
- A23L21/20—Products from apiculture, e.g. royal jelly or pollen; Substitutes therefor
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L25/00—Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
- A23L25/30—Mashed or comminuted products, e.g. pulp, pastes, meal, powders; Products made therefrom, e.g. blocks, flakes, snacks; Liquid or semi-liquid products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention belongs to field of health care products, specifically provides a kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis, and the active ingredient contained by it is prepared by the extraction of following raw materials in part by weight medicine：20 30 parts of Xuancheng's pawpaw, 10 20 parts of fingered citron, 6 10 parts of pollen of Semen Fagopyri Esculenti, 8 12 parts of spina date seed, 15 25 parts of cassia seed, 10 20 parts of fructus alpiniae oxyphyllae, 8 12 parts of pueraria lobata, 46 parts of radix bardanae, the present invention, which can treat, improves osteoporosis and raising bone density.
Description
Technical field
The present invention relates to health product technology field, and in particular to a kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis.
Background technology
Xuancheng's pawpaw, which originates in small towns, Jingxian County, the Ningguo such as Shui Dong, Sun Bu of Xuanzhou District, new field, all kings, Xi Kou, Jin Ba, also to be had few
Amount production.Xuancheng's pawpaw is warm-natured, sour-puckery flavor, there is the diseases such as relaxing tendons and activating collaterals, wind-dispelling arthritis with fixed pain caused by dampness.Ancient medicine scholar Tao Hongjing, Su Song, Li Shi
Treasure has higher rating.《Compendium of Materia Medica》Carry：" pawpaw has it everywhere, and Xuancheng person is optimal ", therefore have the title of Xuancheng's pawpaw.Xuanzhou District
The Xuancheng's pawpaw of plantation, existing more than 1500 years history, has been set in period " tribute " early in the Northern and Southern Dynasties.
Osteoporosis, that is, osteoporosis, is one group of osteopathy caused by many reasons, and bone tissue has normal calcification, calcium salt
It is in normal rates with matrix, the metabolic bone disease with the characteristics of the reduction of unit volume inner bone tissues amount becomes.In most osteoporosises
In, caused by the reduction of bone tissue increases mainly due to bone absorption.By skeleton pain, be easy to fracture characterized by.For this reason, being bursting to out
Send the needs that more health products for safely and effectively improving osteoporosis meet health care.
The content of the invention
To solve the above-mentioned problems, it is an object of the invention to provide a kind of Xuancheng's pawpaw generation meal for being used to improve osteoporosis
Powder.In order to reach this purpose, adopt the following technical scheme that：
Technical solution：A kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis, the active ingredient contained by it is by following heavy
The bulk pharmaceutical chemicals extraction of amount part is prepared：20-30 parts of Xuancheng's pawpaw, 10-20 parts of fingered citron, 6-10 parts of pollen of Semen Fagopyri Esculenti, 8-12 parts of spina date seed,
15-25 parts of cassia seed, 10-20 parts of fructus alpiniae oxyphyllae, 8-12 parts of pueraria lobata, 4-6 parts of radix bardanae.
The Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis, the active ingredient contained by it is by following raw materials in part by weight medicine
Extraction is prepared：25 parts of Xuancheng's pawpaw, 15 parts of fingered citron, 8 parts of pollen of Semen Fagopyri Esculenti, 10 parts of spina date seed, 20 parts of cassia seed, fructus alpiniae oxyphyllae 15
Part, 10 parts of pueraria lobata, 5 parts of radix bardanae.
The Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis, formulation is pulvis.
The Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis, preparation process are：Above-mentioned raw materials are taken, are crushed, cross 80 mesh
Sieve, packing, up to Xuancheng's pawpaw meal replacement powder.
The Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis is preparing the application in improving osteoporosis health products.
The Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis is preparing the application in improving bone density health products.
Beneficial effect：Xuancheng's pawpaw contains 19 kinds of amino acid, 18 kinds of mine trace elements, and vitamin C, together
When also containing saponin, flavones, malic acid, oleanolic acid, citric acid, citric acid, tartaric acid, ascorbic acid, fumaric acid, tan
Matter etc., containing catalase, phenol oxidase, oxidizing ferment, especially rich in hepatocuprein (SOD) and oleanolic acid.Its
The content of SOD is impayable in all fruit in the world, and it is international single that the content of one gram of Xuancheng's pawpaw fresh fruit SOD is up to 3227
Position.SOD is the core substance of modern beauty beauty treatment product, can effectively eliminate superfluous free radical in vivo, promote body cell more
Newly.Oleanolic acid has broad-spectrum antibacterial action, has the effects such as protect liver drop enzyme, promoting immunity, anti-inflammatory, reducing blood lipid blood glucose.Fingered citron is used
In stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food vomiting, coughing with a lot of sputum.Pollen of Semen Fagopyri Esculenti can promote the development of immune organ；
Prevent infringement of the immunodepressant to immune organ；Accelerate the generation of antibody and delay the disappearance of antibody；Promote T lymphocytes and
The increase of macrophage, and the phagocytic activity of macrophage can be improved, so as to improve the immune function of body comprehensively.Spina date seed taste
It is sweet, sour, it is mild-natured.Conscience can be nourished, is calmed the nerves, arrest sweating.Cassia seed is legume Cassia or the dry mature seed of little Cassia tora, with
It has the work(of improving eyesight and name it.Autumn harvests ripening fruits, dries, and lays seed, removes impurity.It is cassia seed bitter, sweet, salty,
Cold nature, enters liver, kidney, large intestine channel；Relax bowel, lipid-loweringing improving eyesight, treats constipation and hyperlipidemia, hypertension.Clear liver and improve vision, Li Shui
Defaecation, there is laxative action, reducing blood pressure and blood fat.Fructus alpiniae oxyphyllae is the fruit of zingiberaceous plant intelligence development Alpinia oxyphylla Miq.
It is real.Guangdong and Hainan are distributed in, also there is cultivation in Fujian, Guangxi, Yunnan.Saliva is taken the photograph with warming spleen and stopping diarrha, warms up the work(of kidney contracting urine controlling nocturnal emission with astringent drugs
Effect.It is usually used in deficiency-cold in spleen and stomach, vomits, diarrhea, crymodynia in abdomen, the more salivas of mouth, enuresis with renal asthenia, frequent micturition, seminal emission, gonorrhoea.Pueraria lobata is
The dry root of legume pueraria lobata, practises and claims elegant jessamine.Autumn, the excavation of two season of winter, take advantage of fresh-cut into sheet or fritter；It is dry.It is sweet, pungent, it is cool.
There is expelling pathogenic factors from muscles and skin to bring down a fever, promoting eruption, promotes the production of body fluid to quench thirst, the work(of Shengyang Zhixie.It is usually used in exterior syndrome fever, stiff nape and back, measles without adequate eruption, pyreticosis mouth
Yearningly, the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea.Radix bardanae is the root of feverfew burdock Arctium lappa L..Burdock point
It is distributed in the ground such as northeast, northwest, Central-South, southwestern and Hebei, Shanxi, Shandong, Jiangsu, Anhui, Zhejiang, Jiangxi, Guangxi.With relieve heat
The effect of heat, disinfection is swollen.It is usually used in anemopyretic cold, has a headache, cough, heat toxin edema of the face, abscess of throat, gingivitis, arthralgia pain due to rheumatism,
Wei lump in the abdomen accumulates block, carbuncle furuncle malignant sore, hemorrhoid rectal prolapse.Xuancheng's pawpaw of the present invention, fingered citron, pollen of Semen Fagopyri Esculenti are monarch drug in a prescription, spina date seed, cassia seed, benefit
Intelligence benevolence, pueraria lobata are ministerial drug, and radix bardanae is adjuvant, and the complete mutual compatibility in side, treats osteoporosis positive effect.
Embodiment
Form by the following examples, is described in further detail the above of the present invention again, but should not be by this
The scope for being interpreted as the above-mentioned theme of the present invention is only limitted to following example, and all technologies for being realized based on the above of the present invention are equal
Belong to the scope of the present invention.
Embodiment 1：Take 20 parts of Xuancheng's pawpaw, 20 parts of fingered citron, 6 parts of pollen of Semen Fagopyri Esculenti, 12 parts of spina date seed, 15 parts of cassia seed, intelligence development
20 parts of benevolence, 8 parts of pueraria lobata, 6 parts of radix bardanae, preparation process are：Above-mentioned raw materials are taken, are crushed, cross 80 mesh sieves, packing, up to Xuancheng's pawpaw
Meal replacement powder.
Embodiment 2：Take 30 parts of Xuancheng's pawpaw, 10 parts of fingered citron, 10 parts of pollen of Semen Fagopyri Esculenti, 8 parts of spina date seed, 25 parts of cassia seed, intelligence development
10 parts of benevolence, 12 parts of pueraria lobata, 4 parts of radix bardanae, preparation process are：Above-mentioned raw materials are taken, are crushed, cross 80 mesh sieves, packing, up to Xuancheng's pawpaw
Meal replacement powder.
Embodiment 3：Take 25 parts of Xuancheng's pawpaw, 15 parts of fingered citron, 8 parts of pollen of Semen Fagopyri Esculenti, 10 parts of spina date seed, 20 parts of cassia seed, intelligence development
15 parts of benevolence, 10 parts of pueraria lobata, 5 parts of radix bardanae, preparation process are：Above-mentioned raw materials are taken, are crushed, cross 80 mesh sieves, packing, up to Xuancheng's pawpaw
Meal replacement powder.
Embodiment 4：Xuancheng's pawpaw meal replacement powder of the present invention improves osteoporosis clinical research
General data：Xuancheng's pawpaw meal replacement powder is applied to osteoporosis case 50,43~69 years old age.The most short person of the course of disease
6 months, most elder was up to 6 years.
Diagnostic criteria：1. pain, mainly back is had aches in the limbs, or whole body skeletal pain；2. fracture, mainly vertebra wedge sample
Change or compression fracture, or limbs fracture；3. x-ray changes, thinning with cortex of bone, bone trabecula becomes loose and is characterized, and 4. bone is close
Degree measure, bone mineral content density (BMD) are less than peak bone mass 1-2.5 standard deviations.
Test method：Clinical sample is prepared by 3 preparation method of above-described embodiment, specification is 10 grams every bag, is treated for one within five days
Journey, one day three bags, it is point early, middle and late that half an hour takes before meals three times.Raw and cold, pungent, stimulation is avoided eating during medication and rots it
Thing.Blank group oral placebo pulvis, five days as a treatment course, one day three bags, it is point early, middle and late that half an hour takes before meals three times.
Criterion of therapeutical effect：Recovery from illness：Back limbs pain symptom disappears, and bone density inspection shows bone density increase；Effectively：Back
Limbs pain symptom is relieved, and bone density is without increase；It is invalid：With compare no improvement before treatment.
Therapeutic effect：It is shown in Table.
Two groups of curative effects compare
| Group | n | Recovery from illness | Effectively | It is invalid | Total effective rate (%) |
| Treatment group | 25 | 8 | 15 | 2 | 92 |
| Blank group | 25 | 0 | 1 | 24 | 4 |
As it can be seen that Xuancheng's pawpaw meal replacement powder of the present invention can safely and effectively improve osteoporosis, and have no toxic side effect.
Embodiment 5：The pharmacodynamic study of influence of the Xuancheng's pawpaw meal replacement powder of the present invention to the bone density of experimental animal
Sample preparation：Xuancheng's pawpaw meal replacement powder is prepared as test specimen by above-described embodiment 3, and specification is 10g/ bags, calcium that
Strange piece, Pfizer Inc., lot number：20150711.Tretinoin piece, Shandong Liang Fu pharmaceutical Co. Ltds, lot number：160220
Animal：Wistar rats, male, weight 180-240g, Medical University Of Anhui's Experimental Animal Center provide.
The foundation of experiment packet and model rat with osteoporosis：Take normal Wistar rats 30 to be only randomly divided into 5 groups, take it
In 6 be NS groups；Take wherein 6 to be only used as model group, press Tretinoin 70mg/kg gavages merely two weeks；Wherein 6 are taken to be only used as calcium that
Strange piece control group；Remaining 12 rats are as the high low dose group of the present invention.It is high and low as the strange piece control group of calcium that and the present invention
Dosage group gavages corresponding medicine while gavaging Tretinoin by the dosage of 70mg/kg, gavage withdraw after two weeks Tretinoin continue to
Two weeks measure indices of medicine.Rat sacrificed by decapitation, take its femur by group arrangement, using X- line mammary gland video camera produce mating plate,
With black and white densitometer in 5 positions fixed point measures on the greater trochanter of femur, femoral head, neck of femur, intertrochanteric line and under intertrochanteric line
And record bone density value.
Influence to rat bone density
Compared with model group, * 1P<0.01,*2P<0.05
Test result indicates that Xuancheng's pawpaw meal replacement powder of the present invention compared with model group, has significant difference, illustrates the present invention
Xuancheng's pawpaw meal replacement powder can improve bone density, treatment fracture, and effect better than the strange piece of calcium that.
Claims (6)
1. a kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis, it is characterised in that the active ingredient contained by it is by following heavy
The bulk pharmaceutical chemicals extraction of amount part is prepared：20-30 parts of Xuancheng's pawpaw, 10-20 parts of fingered citron, 6-10 parts of pollen of Semen Fagopyri Esculenti, 8-12 parts of spina date seed,
15-25 parts of cassia seed, 10-20 parts of fructus alpiniae oxyphyllae, 8-12 parts of pueraria lobata, 4-6 parts of radix bardanae.
2. be used to improve the Xuancheng's pawpaw meal replacement powder of osteoporosis as claimed in claim 1, it is characterised in that activity contained by it into
Divide and be prepared by the extraction of following raw materials in part by weight medicine：25 parts of Xuancheng's pawpaw, 15 parts of fingered citron, 8 parts of pollen of Semen Fagopyri Esculenti, 10 parts of spina date seed,
20 parts of cassia seed, 15 parts of fructus alpiniae oxyphyllae, 10 parts of pueraria lobata, 5 parts of radix bardanae.
3. it is used for the Xuancheng's pawpaw meal replacement powder for improving osteoporosis as claimed in claim 1, it is characterised in that formulation is pulvis.
4. it is used to improve the Xuancheng's pawpaw meal replacement powder of osteoporosis as claimed in claim 1, it is characterised in that preparation process is：Take
Above-mentioned raw materials, crush, and cross 80 mesh sieves, packing, up to Xuancheng's pawpaw meal replacement powder.
5. the Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis according to claim 1 is preparing improvement osteoporosis health products
In application.
6. the Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis according to claim 1 is in raising bone density health products are prepared
Application.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711154292.4A CN107927643A (en) | 2017-11-20 | 2017-11-20 | A kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711154292.4A CN107927643A (en) | 2017-11-20 | 2017-11-20 | A kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107927643A true CN107927643A (en) | 2018-04-20 |
Family
ID=61931902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711154292.4A Withdrawn CN107927643A (en) | 2017-11-20 | 2017-11-20 | A kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107927643A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181065A (en) * | 2006-11-13 | 2008-05-21 | 洛阳梓生科技开发有限公司 | Method for preparing capsule for increasing bone density |
| CN101181422A (en) * | 2007-11-21 | 2008-05-21 | 北京中科雍和医药技术有限公司 | Nutrition health products for curing osteosporosis and rheumatic osteoarthropathy as well as preparation method |
| CN105434579A (en) * | 2014-11-21 | 2016-03-30 | 青岛华之草医药科技有限公司 | Traditional Chinese medicine for treating bone rarefaction |
| CN105435025A (en) * | 2016-01-08 | 2016-03-30 | 姜新海 | Pure traditional Chinese herbal capsule for effectively treating osteoporosis |
| CN107212256A (en) * | 2017-06-20 | 2017-09-29 | 秦皇岛长胜营养健康科技有限公司 | A kind of meal replacement powder with function of blood sugar reduction and preparation method thereof |
-
2017
- 2017-11-20 CN CN201711154292.4A patent/CN107927643A/en not_active Withdrawn
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181065A (en) * | 2006-11-13 | 2008-05-21 | 洛阳梓生科技开发有限公司 | Method for preparing capsule for increasing bone density |
| CN101181422A (en) * | 2007-11-21 | 2008-05-21 | 北京中科雍和医药技术有限公司 | Nutrition health products for curing osteosporosis and rheumatic osteoarthropathy as well as preparation method |
| CN105434579A (en) * | 2014-11-21 | 2016-03-30 | 青岛华之草医药科技有限公司 | Traditional Chinese medicine for treating bone rarefaction |
| CN105434580A (en) * | 2014-11-21 | 2016-03-30 | 青岛华之草医药科技有限公司 | Traditional Chinese medicine for treating bone rarefaction and preparation method thereof |
| CN105435025A (en) * | 2016-01-08 | 2016-03-30 | 姜新海 | Pure traditional Chinese herbal capsule for effectively treating osteoporosis |
| CN107212256A (en) * | 2017-06-20 | 2017-09-29 | 秦皇岛长胜营养健康科技有限公司 | A kind of meal replacement powder with function of blood sugar reduction and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103251873A (en) | Traditional Chinese veterinary medicine capable of helping to digest and remove retention | |
| CN109589359A (en) | A kind of Chinese medicine composition for improving sow production performance, Chinese medicine microecological preparation and preparation method thereof | |
| CN106938005A (en) | A kind of Chinese medicine composition for being used to treat osteoporosis | |
| CN102895319A (en) | Composition containing desert cistanche, cynomorium or medlar, pumpkin seeds and pollen | |
| CN102743657B (en) | Traditional Chinese medicine composition for preventing piglet dysentery and preparation method thereof | |
| CN106511864A (en) | Traditional Chinese medicine composition and preparation method and applications thereof in treatment of cervical carcinoma | |
| CN105031408B (en) | A kind of composition improving gout | |
| CN106387434A (en) | Traditional Chinese medicine and microorganism compound feed additive for fattening pigs | |
| CN104524462A (en) | Traditional Chinese medicine formula for treating craniocerebral injury or intracranial tumour postoperative vertigo | |
| CN103040975B (en) | Traditional Chinese medicine composition for nursing and treating infantile diarrhea | |
| CN107927643A (en) | A kind of Xuancheng's pawpaw meal replacement powder for being used to improve osteoporosis | |
| CN104984122A (en) | Chinese herbal medicament for treating tetanus and preparation method thereof | |
| CN105497575A (en) | Traditional Chinese medicinal preparation for treating dysthymia | |
| CN107854662A (en) | A kind of Chinese medicine preparation for treating cirrhotic ascites and preparation method thereof | |
| CN105748958A (en) | Traditional Chinese medicine composition for treating bowel dysfunction | |
| CN106421411A (en) | Stomach tonifying functional beverage | |
| CN107625863B (en) | Compound traditional Chinese medicine soft capsule for treating rheumatism bone disease and preparation method thereof | |
| CN105920070A (en) | Traditional Chinese medicine composition for treating cataract and preparation method thereof | |
| CN103330861A (en) | Medicine for curing cholera and preparation method thereof | |
| CN105497574A (en) | Chinese herbal preparation for treating dysthymia | |
| CN103830687A (en) | Waist strain treatment traditional Chinese medicine composition and preparation method thereof | |
| CN104687029A (en) | Formula and production method of ginseng soup stock for maintaining beauty and keeping young | |
| CN102793894A (en) | Traditional Chinese medicine for treating mental disease | |
| CN102641442A (en) | Traditional Chinese medicine preparation for treating recurrent aphthae | |
| CN109078174A (en) | A kind of biological composition for preventing and treating gingival carcinoma |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20181205 Address after: 242000 Pioneering Road 23-3-2, Xuancheng Economic and Technological Development Zone, Xuancheng City, Anhui Province Applicant after: XUANCHENG HUAKE XUANMUGUA BIOTECHNOLOGY CO., LTD. Address before: 242000 Dangui Apartment, Renmin Road, Ningguo City, Xuancheng City, Anhui Province, 2 West 112 Storage, West 112, West 212 Applicant before: Ningguo balanced Health Management Company Limited |
|
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180420 |