CN107923921A - Automatic analysing apparatus - Google Patents

Abstract

In automatic analysis apparatus of the present invention, with the action of reagent equipped section (103), make second (201), first (202) automatic shutter of the second cold storage box (110).Left in reagent equipped section (103) from the second cold storage box (110), after second (201), first (202) are opened, second (201), first (202) are locked automatically by door lock hole (203), door lock mechanism (204), door lock roller (206) so that second (201), first (202) are not closed.In addition, by reagent equipped section (103) be accommodated in the second cold storage box (110) it is interior when, second (201), first (202) automatically terminate locking, and are accommodated in the second cold storage box (110).Thus, the installation space of mechanism can be saved, reduce component parts, and failure risk can be reduced, without setting the actuator for the door for being used to be opened and closed reagent cold storage box.

Description

Automatic analysing apparatus

Technical field

The present invention relates to concentration of the predetermined component in the liquid samples such as blood, urine etc. is analyzed using reagent Automatic analysing apparatus, more particularly to carries out the automatic analysing apparatus that move-in/move-out is used for the reagent of analysis automatically.

Background technology

A kind of automatic analysing apparatus is recorded in patent document 1, as mitigation since reagent registration, reagent replacement etc. are made Industry causes the automatic analysing apparatus born and reagent deficiency does not occur in analysis, minimize analysis interruption of operator One example, is arranged at the second examination as supplement every 2 one row of automatic analysing apparatus reagent container on reagent disc The supplement of agent Keeping Unit reagent safe-deposit vault, multiple reagent containers can be carried in supplement reagent safe-deposit vault, tried in supplement Track is configured with agent safe-deposit vault, be provided with orbit the reagent holding unit that can be moved with track on 3 direction of principal axis and Reagent lid opens bolt unit.

Prior art literature

Patent document

Te Xu documents 1:Japanese Patent Laid-Open 2005-37171 publications

The content of the invention

The technical problems to be solved by the invention

For example, it is necessary to will be with the automatic analysing apparatus such as biochemistry automatic analysing apparatus, immune automatic analysing apparatus The corresponding reagent of measure project of patient's corpse or other object for laboratory examination and chemical testing is arranged in device.By reagent bottle set to the reagent device in be usually by Operator's manual setting is in reagent disc.

The usual operation of the replacement of reagent bottle be substantially device be not carried out measure it is standby when etc. progress.For example, Take following methods：In the less grade of the reagent of some measure project, grasped in advance with reagent before patient's corpse or other object for laboratory examination and chemical testing is measured The number that surplus can measure, new same reagent bottle is added be arranged at reagent disc etc. in advance when surplus is less.

Acted the reason for this is that surveying centering device in a corpse or other object for laboratory examination and chemical testing, therefore reagent bottle can not be added, take out emptying reagent Bottle.Therefore, become when being supplemented when reagent tails off in the assay reagent bottle, it is necessary to complete measure when device For standby state, so as to produce the stand-by period of operator, workability is deteriorated, and produces loss of minute etc. and lack Point.

Herein, since the setting of reagent bottle is that 1 setting of operator 1 is moved into reagent disc again to device, so spending Time, therefore there are claimed below：Wish that reagent bottle setting is collected a degree of number continuously moves into reagent disc again.

The automatic analysing apparatus of patent document 1 is recorded in order to meet the requirement, reagent holding unit is set, it can be set Multiple reagent bottles place reagent.+ in addition, reagent holding unit use is acted all around on direction in the device Structure, therefore as reagent bottle can be arranged to the structure of reagent disc with the continuous action of automation.Moreover, the of supplement Two reagent safe-deposit vaults possess cold insulation function.

However, in patent document 1, do not record on how to take into account the second reagent safe-deposit vault ensured in supplement While cold insulation function, reagent holding unit takes out of the function of reagent bottle from the second reagent safe-deposit vault.

In above-mentioned patent document 1, in the machine for merely setting reagent holding unit to enter to the second reagent safe-deposit vault In the case of structure, the function to reagent bottle cold insulation and the mechanism of reagent holding unit entrance, take care of in the second reagent in order to balance The switching mechanism of lab setting door, sets be used to for reagent bottle to be moved to mechanism of extracting position etc., it is necessary to configure complexity in addition Mechanism.However, there are problems with：The actuator for shutter door, installation space is set to become larger, components number becomes more.That is, energy Imagination apparatus structure also becomes complicated, failure equivalent risk also becomes higher.

The present invention provides a kind of automatic analysing apparatus, can realize the space saving of the installation space of mechanism, reduce constituting portion Part, can reduce failure risk without setting the actuator for shutter door.

Solve the technical solution of technical problem

To solve the above-mentioned problems, for example with the structure described in Patent right requirement.

The present invention includes multiple units to solve the above problems, is listed below a wherein example：A kind of automatic analysing apparatus, anti- Answer and sample and reagent are injected separately into container, make sample and reagent reacting, and the liquid after the reaction is measured, this is automatic Analytical equipment is characterized in that, including：Reagent disc, it takes care of the reagent bottle for having stored the reagent；Reagent equipped section, It is used for when moving into the reagent bottle to the automatic analysing apparatus, sets multiple reagent bottles；And reagent is protected Freezer, it carries out cold insulation to the reagent bottle for being arranged at the reagent equipped section together with the reagent equipped section, described Reagent cold storage box has shutter door, it is opened and closed with the disengaging action of the reagent equipped section, for supplying the reagent Equipped section passes in and out.

Invention effect

According to the present invention, it can realize the space saving of the installation space of mechanism, reduce component parts, failure risk can be reduced Without setting the actuator for shutter door.

Brief description of the drawings

Fig. 1 is the integrally-built synoptic diagram for showing general automatic analysing apparatus.

Fig. 2 is that one of the automated loading mechanism for being arranged at automatic analysing apparatus for illustrating embodiments of the present invention is exemplary general Scheme.

Fig. 3 is one of the action for the automated loading mechanism for being arranged at automatic analysing apparatus for illustrating embodiments of the present invention and shows The synoptic diagram of example.

Fig. 4 is another exemplary summary of the shutter door of the action for the automated loading mechanism for illustrating embodiments of the present invention Figure.

Fig. 5 is the reagent equipped section for the automated loading mechanism for being arranged at automatic analysing apparatus for illustrating embodiments of the present invention One exemplary synoptic diagram of structure.

Fig. 6 is an exemplary summary of the action of the door lock mechanism for the automated loading mechanism for illustrating embodiments of the present invention Figure.

Fig. 7 is one of the action for the automated loading mechanism for being arranged at automatic analysing apparatus for illustrating embodiments of the present invention and shows The synoptic diagram of example.

Fig. 8 is one of the action for the automated loading mechanism for being arranged at automatic analysing apparatus for illustrating embodiments of the present invention and shows The synoptic diagram of example.

Fig. 9 is one of the action for the automated loading mechanism for being arranged at automatic analysing apparatus for illustrating embodiments of the present invention and shows The synoptic diagram of example.

Figure 10 is one of the action for the automated loading mechanism for being arranged at automatic analysing apparatus for illustrating embodiments of the present invention Exemplary synoptic diagram.

Figure 11 is one of the action for the automated loading mechanism for being arranged at automatic analysing apparatus for illustrating embodiments of the present invention Exemplary synoptic diagram.

Figure 12 is one of the action for the automated loading mechanism for being arranged at automatic analysing apparatus for illustrating embodiments of the present invention Exemplary synoptic diagram.

Figure 13 is an exemplary summary of the action of the door lock mechanism for the automated loading mechanism for illustrating embodiments of the present invention Figure.

Figure 14 is an exemplary summary of the action of the door lock mechanism for the automated loading mechanism for illustrating embodiments of the present invention Figure.

Embodiment

Illustrate the embodiment of automatic analysis apparatus of the present invention using Fig. 1 to Figure 14.

Fig. 1 is the stereogram of the automatic analysing apparatus of present embodiment.

In Fig. 1, automatic analysing apparatus is that sample and reagent are injected separately into multiple reaction vessels 2 to make the sample and examination Agent is reacted, and the device that the liquid after the reaction is measured, the automatic analysing apparatus are included：Reaction tray 1；Reagent disc 9；Reagent transport mechanism 17；Reagent distributor gear 7,8；Reagent syringe 18；Sample distributor gear 11；Sample syringe 19；Wiper mechanism 3；Light source 4a；Spectrophotometer 4；Rabbling mechanism 5,6；Flushing pump 20；Rinse bath 13,30,31,32,33； Controller 21；And automated loading mechanism 100 (with reference to Fig. 2).

Reaction vessel 2 is arranged with the circumference of reaction tray 1.Sample transport mechanism 17 is provided near reaction tray 1, The sample transport mechanism 17 is moved the stent 16 for being loaded with sample container 15.

The sample distributor gear 11 that can be rotated and move up and down is provided between reaction tray 1 and sample transport mechanism 17, And possesses sample probe 11a.Sample syringe 19 is connected with sample probe 11a.Sample probe 111a is with rotation axis Centered on draw and circular arc and be carried out at the same time movement, sample distribution is carried out from sample container 15 to reaction vessel 2.

Reagent disc 9 is the safe-deposit vault that can be positioned over reagent bottle 10 on multiple circumference, and examination has been stored in the reagent bottle 10 Agent.Cold insulation is carried out to reagent disc 9, which is covered by cover board, which, which has, is used for the (ginseng of reagent probe suction port 111 According to Fig. 2) and reagent bottle 10 move into the opening and closing cover board 113 (with reference to Fig. 2) in reagent disc 9, which is used for When reagent is allocated in reaction vessel 2, enter for reagent probe 7a, 8a of reagent dispensing mechanism 7,8.

Opening and closing cover board 113 is for not allowing the cover board slipped away by the cold air inside the reagent disc 9 of cold insulation, usually closing shape State.Reagent transport mechanism 101 described later close to reagent disc 9 when, opening and closing cover board 113 open, the reagent transport mechanism 101 into Action is made it possible in 10 move-in/move-out reagent disc 9 of reagent bottle.

Between reaction tray 1 and reagent disc 9, the reagent distributor gear 7,8 that can be rotated and move up and down is provided with, and divide Do not possess reagent probe 7a, 8a.Reagent syringe 18 is connected with reagent probe 7a, 8a.Reagent probe 7a, 8a are to rotate Circular arc is drawn centered on axis and is carried out at the same time movement, to be entered to from reagent probe suction port 111 in reagent disc 9, from reagent bottle 10 carry out the dispensing of reagent to reaction vessel 2.

Wiper mechanism 3, light source 4a, spectrophotometer 4 and rabbling mechanism 5,6 are also configured with around reaction tray 1. Flushing pump 20 is connected with wiper mechanism 3.Reagent dispense mechanism 7,8, sample distributor gear 11, rabbling mechanism 5,6 it is dynamic Rinse bath 13,30,31,32,33 is respectively arranged with as scope.Blood etc., which is included, in sample container 15 checks sample (corpse or other object for laboratory examination and chemical testing), should Sample container 15 is placed in stent 16 and is carried by sample transport mechanism 17.In addition, each mechanism is connected to controller 21.

Controller 21 is made of computer etc., and the action to each mechanism in automatic analysing apparatus is controlled and carries out Calculation process is in the hope of going out the concentration of the predetermined component in the liquid samples such as blood, urine.

Above is the general structure of automatic analysing apparatus.

The analyzing and processing of the inspection sample of above-mentioned automatic analysing apparatus is performed generally according to following steps.

First, the sample in sample container 15 is distributed to reaction tray 1 by the sample probe 11a of sample distributor gear 11 On reaction vessel 2, which is placed in the stent 16 being transmitted to by sample transport mechanism 17 near reaction tray 1 On.Then, will be distributed using reagent bottle 10 of the reagent distributor gear 7,8 from reagent disc 9 for the reagent of analysis to advance point The reaction vessel 2 of sample is matched somebody with somebody.Then, the sample in reaction vessel 2 and the mixed liquor of reagent are stirred using rabbling mechanism 5 Mix.

Afterwards, make from the light that light source 4a is produced through the reaction vessel 2 for enclosing mixed liquor, and utilize spectrophotometer 4 The luminosity of transmitted light is measured.It will be sent by the luminosity that spectrophotometer 4 is measured to via A/D converter and interface to control Device 21 processed.Then, computing is carried out using controller 21, obtains the concentration of the predetermined component in the liquid samples such as blood, urine, and profit Result is shown with display unit (not shown) etc..

Then, to the structure of automated loading mechanism 100, illustrated with reference to the attached drawing after Fig. 2.Fig. 2 is to show automatically The figure of the summary of loader mechanism 100.

It is closed in order to be carried out in the reagent probe suction port position of reagent bottle 10 to inside, lid 112 is installed, automatic When being configured in analytical equipment, generally remove lid 112 and be configured in the device.However, in recent years, exist with lower section Method：Hole in 112 notch of lid, is inserted into notch by reagent probe 7a, 8a and attracts the reagent in reagent bottle 10.By It is small notch in the opening portion of the lid 112 of reagent, therefore, contact of the reagent with extraneous gas is minimum, the deterioration of reagent It is compared with the past to be improved.In the above cases, if the new reagent bottle 10 not broken a seal is arranged at automatically by operating personnel In analytical equipment, then reagent bottle 10 112 perforate of lid and be automatically set into reagent disc 9.No matter automated loading mechanism 100 has Without removing lid 112, whether implementing notch to lid 112, automatically by 10 carrying-in/carrying-out of reagent bottle to reagent disc 9.

Automated loading mechanism 100 is configured at the top of reagent disc 9, becomes the structure shown in Fig. 2 etc..In fig. 2, automatic dress Mounted mechanism 100 includes reagent equipped section 103, reagent carrying on mechanism 102, the guarantor of reagent transport mechanism (reagent transport unit) 101, second Freezer (reagent cold storage box) 110, pin rinse bath 108, pin drying mouth 109, bottle direction detection sensor 114 and RFID sensings Device 115.

Reagent equipped section 103 is used for when moving into reagent bottle 10 to automatic analysing apparatus, and operating personnel are to reagent The part that bottle 10 is configured, by reagent carrying on mechanism 102, reagent equipped section 103 carries out on the above-below direction on Fig. 2,3 Action.Reagent equipped section 103 is configured to set multiple reagent bottles 10 on straight line.The reagent equipped section 103 is configured to pair Cold insulation is carried out in multiple reagent bottles 10 that the space of the inside of the second cold storage box 110 is set.For example, reagent equipped section 103 is energy Carry the pallet of multiple reagent bottles 10.Explained below for the details of reagent equipped section 103, reagent carrying on mechanism 102 State.

Second cold storage box 110 is to be used to move into reagent disc 9, the reagent bottle 10 to being arranged at reagent equipped section 103 The cold storage box of cold insulation is provisionally carried out together with reagent equipped section 103.The details of the structure of second cold storage box 110 will be After illustrate.

Reagent transport mechanism 101 is for the reagent bottle 10 for being arranged at reagent equipped section 103 to be sent in reagent disc 9 Mechanism, component parts include：Grasping mechanism (crawl section) 106, the lid 112 in reagent bottle 10 gripped to reagent bottle 10 The reagent bottle of upper perforate uncap bolt mechanism 104, grasping mechanism 106, reagent bottle is uncapped the drive up and down that bolt mechanism 104 moves up and down Move motor (not shown) and grasping mechanism 106, reagent bottle is uncapped what right and left of the bolt mechanism 104 on Fig. 2 drove up Horizontal drive motor 131.

Reagent transport mechanism 101 from the position of the reagent equipped section 103 of Fig. 2 to opening and closing cover board 113 position, Acted on left and right directions on Fig. 2.That is, it is configured to：Reagent equipped section 103 is moved on the above-below direction on Fig. 2, Reagent transport mechanism 101 is acted in the horizontal direction on Fig. 2, therefore direction of action is orthogonal.In addition, reagent conveyer Structure 101 is linearly configured at the position gripped by grasping mechanism 106 to reagent bottle 10 and moves into reagent bottle 10 Take out of to the position of reagent disc 9.

Reagent bottle bolt mechanism 104 of uncapping is provided with pin 105 for cutting out notch in the lid 112 of reagent bottle 10.Trying Agent bottle is uncapped in bolt mechanism 104, is configured to：Cleaned using the pin for the direction of action for being abreast configured at reagent transport mechanism 101 Groove 108 cleans the pin 105 after notch is cut out on lid 112, in next process, by being abreast configured at examination The pin of the direction of action of agent transport mechanism 101 dries mouth 109 to remove ejected wash water, and notch is cut out in the lid 112 of reagent bottle 10 When, do not allow ejected wash water to dilute reagent.

Grasping mechanism 106, which has, to be used to grip the engagement pawl of reagent bottle 10, passes through lacking the engagement pawl and reagent bottle 10 Oral area engages, so as to be gripped to reagent bottle 10.

Fig. 2 is back to, bottle is configured at the action of reagent equipped section 103 to detection sensor 114 and RFID sensor 115 On.Bottle direction detection sensor 114 sets the setting direction of reagent bottle 10 and reagent bottle 10 to be measured to whetheing there is.RFID is passed Sensor 115 obtains the information for the reagent being recorded in the reagent bottle 10 of RFID tag 10a, wherein, RFID tag 10a is arranged at Reagent bottle 10.

Then, to containing the reagent carrying on mechanism 102 of reagent equipped section 103, the structure of the second cold storage box 110 and moving It is described in detail.First, the structure of the second cold storage box 110 is described in detail using Fig. 3.Fig. 3 is automatic loader The synoptic diagram of structure.

As shown in figure 3, in the second cold storage box 110, the multiple reagent bottles 10 for being arranged at reagent equipped section 103 are protected It is cold.Second cold storage box 110 is configured to carry out reagent equipped section by the opening and closing of second 201 of double door and first 202 103 move-in/move-out, and it is closed to being carried out in the second cold storage box 110 when closed.In addition, second 201 and first The length of 202 door is different.In addition, the inner side of the second cold storage box 110 of first 202 is provided with hook roller (hook roller) 205。

One end of connecting rod 208 is installed on second 201, and the other end is installed on first 202.Connected by connecting rod 208 Connect, therefore second 201 and first 202 is opened and closed action with integrated action in linkage.

In addition, a spring 207, this spring are installed between the fixed part 110A of 208 and second cold storage box 110 of connecting rod 207 be set to all the time by connecting rod 208 into Fig. 3 upper side stretching.That is, second 201, first 202 are in via 208 quilt of connecting rod All the time the state of 110 side of the second cold storage box is pulled to.Door spring 207 with second 201, first 202 open extended And as the mode that second 201, first 202 closings are shunk works.In addition, this spring 207 can be without Second 201, first 202 are directly mounted at by connecting rod 208.

In addition, as shown in Figure 4, the 3rd 209 can be set on second 201, the 3rd 209 in second 201 He First 202 is covered in when closing for first 202.By the 3rd as setting, the second cold storage box 110 can be further improved Interior leak tightness.This is, in the example of fig. 4, the connecting portion of door spring 207 and connecting rod 208 be configured at than first 202 with Connecting portion of the connecting portion of connecting rod 208 closer to second 201 with connecting rod 208.Therefore, the door bullet compared with first 202 The tension force of spring 207 larger puts on second longer 201 side of door.Thus, door spring 207 carries out action so that second 201 and first 202 close contact.In addition, Fig. 4 is another exemplary synoptic diagram of the shutter door of automated loading mechanism 100. In Fig. 4, for the ease of illustration, connecting rod 208 is shown in broken lines.

In the second cold storage box 110, when closing for second 201 and first 202, in order to in the second cold storage box 110 The reagent bottle 10 in portion carries out stably cold insulation, preferably inside is carried out fully closed.This is because it can remain complete close Closed state, can suppress since the temperature difference with extraneous gas causes generation condensation water, reduction to be down to rule inside the second cold storage box The time required to constant temperature degree.Therefore, draw connecting rod 208 to cause second 201 and first 202 by using door spring 207 not open, So as to which even if installation's power source is closed, the air-tight state inside the second cold storage box 110 can be also maintained, can be more stably to reagent bottle 10 Carry out cold insulation.

In addition, in the configuration of the door of Fig. 4, the radius of turn of second 201 becomes larger, therefore even if with first it is 202 same When open two fan doors, the 3rd 209 also can interference-free acted, but in the case where the size of left and right door is identical or think In the case of being arranged at first 202 by the 3rd 209,208 configuration is considered.

Then, the details of reagent equipped section 103 is illustrated using Fig. 5.Fig. 5 is bowing for reagent equipped section 103 View.

In Figure 5, reagent equipped section 103 includes：Main body 103A, the first roller with the space for setting reagent bottle 10 300th, the second front roller 301A, the second rear roller 301B and the 3rd roller 302.It is configured to：Set in the bottom surface side of main body 103A There is gate stop groove 303, hook roller 205 enters to the gate stop groove 303.

First roller 300 is connect in rotating be carried out at the same time in upper surface of reagent carrying on mechanism transmission plane 182, transmission plane 182A Tactile roller, 2 are configured on the right side of main body 103A, are configured 2 in left side, are added up to configuration 4.Pass through first roller 300, examination Agent equipped section 103 can smoothly be moved.

Second front roller 301A and the second rear roller 301B only in the one side of the moving direction of reagent equipped section 103, become The object contacted in Figure 5, it is multiple in the longer second 201 side configuration of length, a part is configured at from main body 103A The protuberance 103B protruded towards the right direction in Fig. 5.

3rd roller 302 is configured at the direction of advance face side of reagent equipped section 103, adds up to 2.

Fig. 3 is back to, reagent carrying on mechanism 102 has：The reagent carrying on mechanism motor 180 of driving reagent equipped section 103, The reagent carrying on mechanism conveyer belt 181, pulley 181A, 181B, reagent carrying on mechanism for being connected to reagent carrying on mechanism motor 180 pass Send face 182, line slideway 183 and the maintaining part 184 for linking reagent carrying on mechanism conveyer belt 181 and reagent equipped section 103.

Reagent equipped section 103 is installed on line slideway 183.In the both sides of line slideway 183, reagent carrying on mechanism transmission plane 182 abreast configure relative to line slideway 183.Above-mentioned line slideway 183 and reagent carrying on mechanism transmission plane 182 plays transmission The effect of line, for reagent bottle 10 to be arranged to the setting position of reagent equipped section 103 and the second guarantor for reagent equipped section 103 Moved between freezer 110.

Reagent carrying on mechanism conveyer belt 181 is abreast configured with the grade of line slideway 183, takes reagent via maintaining part 184 Mounted mechanism conveyer belt 181 and reagent equipped section 103 link.The maintaining part 184 has the portion contacted with the door of the second cold storage box 110 Split-phase is for the sufficiently thin structure of the seal that is arranged at the door of the second cold storage box 110 (one piece metallic plate etc.) so that second protects Low temperature is maintained in freezer 110.This is because：The part composition with the cap contacts of the second cold storage box 110 of the maintaining part 184 To be clamped by the main body of door and the second cold storage box 110, therefore by the way that the part is set to sufficiently thin structure, so as to can ensure that gas Close property.It is configured to：Pulley 181A, 181B, reagent carrying on mechanism motor are installed at the both ends of reagent carrying on mechanism conveyer belt 181 180, by reagent carrying on mechanism motor 180 carry out rotation so as to via pulley 181A make reagent carrying on mechanism conveyer belt 181 into Row rotates in linkage, and with the rotary motion of the reagent carrying on mechanism conveyer belt 181, via maintaining part 184, machine is carried with reagent Acted on the above-below direction of the reagent equipped section 103 that structure conveyer belt 181 links in figure 3.

In addition, reagent equipped section 103 is being provided with door with the maintaining part 184 that reagent carrying on mechanism conveyer belt 181 is connected Lock roller 206.On the door lock roller 206 in rear elaboration.

In addition, the left side and the right side between reagent carrying on mechanism transmission plane 182 and the transmission plane 182A of the second cold storage box 110 Side, is provided with gap 200A, 200B.Gap 200A close to second 201 side is the opening and closing track in order to ensure second 201 And set, the gap 200B close to first 202 side is set in order to ensure the opening and closing track of first 202.

In addition, such as lower structure can be used, reagent carrying on mechanism transmission plane 182 is extended into the second cold storage box 110, so that Reagent equipped section 103 is stored in the second cold storage box 110.However, in order to ensure the when closing for second 201, first 202 Closed in two cold storage boxes 110 is, it is necessary to new structure, for ensuring that second 201, first 202 pass with reagent carrying on mechanism Send the closed of the part of the interference of face 182.In this case, structure becomes more sophisticated, and components number becomes more.However, pass through Gap 200A, 200B are set between reagent carrying on mechanism transmission plane 182 and the second cold storage box 110, so as to merely comprise only to need Ensure the leak tightness of maintaining part 184, thus realize further reduce components number, further improve it is related to cold insulation ability Reliability.

In addition, the outside of the second cold storage box 110 of second 201 is provided with door lock hole 203.

Moreover, being provided with auxiliary transmission plane 185 the inner side of the second cold storage box 110 of second 201, taken for filling reagent Gap 200A between mounted mechanism transmission plane 182 and transmission plane 182A.When opening for second 201, which exists It is attached in the state of the inner side of second 201 while opens, when opens for second 201 to reagent carrying on mechanism transmission plane The major part of gap 200A between 182 and transmission plane 182A is filled.Thus, the reagent carrying on mechanism on right side passes in Fig. 3 The guide rail of 182 side of face is sent to complete.Although the interval of gap 200B becomes larger, reagent equipped section 103 is left from the second cold storage box 110 When the first roller 300 be placed in the auxiliary transmission plane 185 of second 201 of opening, and multiple first rollers 300 are provided with, so as to try Agent equipped section 103 can carry out fore-aft motion without any problems to be transmitted.

Herein, the first roller 300 of reagent equipped section 103 is moved with crossing gap 200A, 200B, therefore is preferably to try First roller 300 of agent equipped section 103 is more than the gap of 182 side of reagent carrying on mechanism transmission plane on right side in Fig. 3.

In addition, the upper surface by making reagent carrying on mechanism transmission plane 182, auxiliary transmission plane 185 and transmission plane 182A The height alignment of side, so that even if having gap 200A, 200B, reagent equipped section 103 also can swimmingly be acted.

Moreover, door lock hole 203 is installed at second 201.In addition, door lock machine is independently configured with the door lock hole 203 Structure 204.Door lock mechanism 204 is fixed on the second cold storage box 110, the insertion of door lock mechanism 204 when being fully open for second 201 Rod 204A is inserted into the door lock hole 203 in the outside for being arranged at second 201 (with reference to Fig. 6), prevents second 201 due to door spring 207 tension force and close.Formed using door lock hole 203, door lock mechanism 204 and door lock roller 206 to second 201, first 202 into line-locked locking mechanism so that when being left in reagent equipped section 103 to the outside of the second cold storage box 110, second 201st, do not close for first 202.

As shown in fig. 6, being incorporated with spring 204B in the inside of door lock mechanism 204, becoming insertion rod 204A can be in upper and lower The structure moved up.In the lower position of door lock mechanism 204, the inclined plane part 204C that receives door lock roller 206 and flat is provided with Portion 204D.

In addition, door lock mechanism is not limited to the combination in door lock hole 203, door lock mechanism 204 and door lock roller 206, can include Such as inferior structure：Support to open the structure of maximum door by magnet, carried out using bellows for being arranged at reagent equipped section 103 etc. Locking is so that the structure that door is not closed.The inside of 103 and second cold storage box of reagent equipped section 110 can be carried out by using bellows etc. Connection, so that bellows of extension etc. prevent door to be locked closing.

Above is the second cold storage box 110 and the structure of reagent carrying on mechanism 102.

Then, when opening second 201 and first 202 from the second cold storage box 110 for reagent equipped section 103 and taking out of Action illustrate herein, movement directed downwardly in Fig. 2 is set to take out of direction, movement upward is set to move into direction.

First, in the case where the state entered to from reagent equipped section 103 in the second cold storage box 110 is taken out of, examination Agent carrying on mechanism motor 180 is rotated, and reagent carrying on mechanism conveyer belt 181 is rotated, so that reagent equipped section 103 Start court and take out of direction movement.

If reagent equipped section 103 is further moved, as shown in fig. 7, being installed on the 3rd of the left and right sides of reagent equipped section 103 Roller 302 and the interior side contacts of second 201, first 202, and the second front roller 301A and first of direct of travel front side Door 202 contacts.

From the state of contact, make reagent equipped section in a manner of further expanding second 201 and first 202 103 is mobile to front, then as shown in figure 8, being contacted by second 201 with the second rear roller 301B of direct of travel rear side, It is at a right angle so as to be opened and closed.Although first 202 does not contact with roller, door is synchronously carried out using connecting rod 208 and second 201 On-off action, therefore first 202 at right angles open

As shown in Figure 9, second 201 and first 202 at right angles opening and closing, the insertion rod 204A insertions of door lock mechanism 204 To door lock hole 203, second 201 locked.Therefore, even if being drawn by door spring 207, second 201 and first 202 will not Close.

Action when then, for being received into reagent equipped section 103 in the second cold storage box 110 illustrates.

First, reagent carrying on mechanism motor 180 is rotated in the reverse direction previous, and reagent carrying on mechanism transmits Band 181 is rotated in the reverse direction, so that reagent equipped section 103, which starts court, moves into direction movement.

If reagent equipped section 103 is further moved, the insertion rod 204A of door lock mechanism 204 takes out from door lock hole 203, lock The lock-out state for determining mechanism is released from, using the action of door spring 207, second 201 and first 202 in a manner of closing into Action is made.

In addition, in state as Figure 10, hook roller 205 enters to the gate stop groove 303 of reagent equipped section 103.So Afterwards, if in the state of hook roller 205 enters to gate stop groove 303, reagent equipped section 103 moves further on direction is moved into In two cold storage boxes 110, then as shown in the state of Figure 11, first 202 be entered to the hook roller 205 of gate stop groove 303 drawn it is same When maintain the state that is contacted with the 3rd roller 302, and towards closing direction movement.In addition, by via connecting rod 208 by first 202 are drawn, and second 201 similarly maintains to move towards closing direction while the state contacted with the 3rd roller 302.Afterwards, Fully moved into the second cold storage box 110 by reagent equipped section 103, so as to become air-tight state as shown in Figure 12.Pass through Using above-mentioned gate stop groove 303 and hook roller 205, the closing direction action of second 201 and first 202 can be aided in, The closing direction action of door can more stably be carried out.

Then, illustrated using Fig. 6, Figure 13, Figure 14 for the details of the action of locking mechanism.

Situation about being moved up firstly, for reagent equipped section 103 in the side of taking out of illustrates.It is installed on maintaining part 184 Door lock roller 206 and the movement of reagent equipped section 103 move together, it is therefore close as door lock roller 206 and inclined plane part 204C State.If continuing to move in this condition, door lock roller 206 contiguously advances with inclined plane part 204C, thus spring 204B starts Shrink, insertion rod 204A is lifted upward.If further mobile, door lock roller 206 is contacted with flat part 204D, insertion rod 204A Fully it is raised to upper side.Each component parts is arranged so that in the state as shown in Figure 8 second 201 is vertically beaten Open, therefore door lock hole 203 is configured at the underface of insertion rod 204A.

If the movement of reagent equipped section 103 continues to, door lock roller 206 is contacted with inclined plane part 204C, passes through spring The effect of 204B, insertion rod 204A start to move downward.Afterwards, if door lock roller 206 is separated with inclined plane part 204C, such as Figure 14 Like that, insertion rod 204A, which is inserted into, is installed on the door lock hole 203 of second 201.Therefore, for second 201 and first 202, even if the power of the compression stress of door spring 207, i.e. closing direction is acted on, second 201 and first 202 still maintains to beat The state opened, second 201 as shown in Figure 9 and first 202 open in the state of, reagent equipped section 103 can further to Take out of direction movement.

In reagent equipped section 103 towards in the case of moving into direction movement, become and previous opposite action, first door lock roller 206 contact with inclined plane part 204C, and spring 204B is shunk, and insertion rod 204A is lifted side upward.If being advanced further, door lock roller 206 contact with flat part 204D, and insertion rod 204A is raised to upper side, releases insert state as shown in Figure 13.

Afterwards, door lock roller 206 is contacted with inclined plane part 204C, and insertion rod 204A starts downward due to the effect of spring 204B Fang Yidong, if door lock roller 206 is separated with inclined plane part 204C, as state as Fig. 6, can fully unlock mechanism Lock-out state, closes second 201 and first 202.

Above is the structure of automated loading mechanism 100 and its action.

In addition, on locking mechanism using magnet come the structure that is supported to opening maximum door in the case of, trying When agent equipped section 103 is accommodated in the second cold storage box 110, physically inserted between the position that Men Hemen is in close contact using magnetic force Enter component, so as to weaken the power attracted using magnetic force to the pulling force of spring, so as to unlock.In addition, locking In mechanism using bellows etc. come the structure that is supported to opening maximum door in the case of, be accommodated in reagent equipped section 103 When in the second cold storage box 110, bellows are shunk by the movement with storage, therefore can not be supported on the door, so that It can unlock.

Then, illustrated for the effect of present embodiment.

In above-mentioned present embodiment, automated loading mechanism 100 includes：For being moved into by reagent bottle 10 to automatic point The reagent equipped section 103 of multiple reagent bottles 10 and the reagent bottle to being arranged in reagent equipped section 103 are set when in analysis apparatus 10 carry out the second cold storage box 110 of cold insulation together with reagent equipped section 103, and the second cold storage box 110 has shutter door (second 201 and first 202) it acts and is opened and closed with the disengaging of reagent equipped section 103, for for reagent equipped section 103 into Go out.

In order to carry out cold insulation together with reagent equipped section 103 to reagent bottle 10, door is arranged at the second cold storage box 110 simultaneously The opening and closing for carrying out door as needed is essential.Without using actuator according to the disengaging of reagent equipped section 103 act come Carry out the on-off action of this, without carrying excessive actuator, will not aggrandizement apparatus size, constituting portion can be reduced Part.Moreover, adjustment, maintainability can be improved, device installation space is saved.

In addition, the second front roller 301A, the second rear roller 301B and the 3rd roller by being arranged at reagent equipped section 103 302 contact, so as to be acted with the disengaging of reagent equipped section 103, second 201, first 202 are opened and closed, therefore Each roller is contacted with door when action is opened and closed.Accordingly, it is capable to suppress the loss of the component parts with on-off action, can be steady in a long-term Action is opened and closed in ground.

Moreover, locking mechanism is further included, when it is left in reagent equipped section 103 to the outside of the second cold storage box 110, to Locked for two 201, first 202 so that second 201, first 202 are not closed.Especially, locking mechanism includes： The door lock hole 203 that is arranged at the outside of second 201, first 202, the door lock mechanism 204 for being fixed on the second cold storage box 110, And the door lock roller 206 moved back and forth together with reagent equipped section 103, by when opening for second 201, utilizing door lock Roller 206, door lock hole 203 is inserted into by the insertion rod 204A of door lock mechanism 204, so as to prevent second 201, first 202 passes Close, therefore the state of second 201, first 202 openings can be kept, until reagent equipped section 103 is back to the second cold storage box In 110.When therefore, there is no need to be back in reagent equipped section 103 in second cold storage box 110, reopen second 201, The structure of one 202, while further reducing component parts, further improves adjustment, maintainability, can further save device Installation space.

In addition, having by the second cold storage box 110 fixed part 110A sides are pulled to by second 201, first 202 all the time Door spring 207, so that even if installation's power source is closed, can also maintain the air-tight state inside the second cold storage box 110, can be more stably Carry out the cold insulation of reagent bottle 10.

Moreover, between transmission plane 182A in reagent carrying on mechanism transmission plane 182 and the second cold storage box 110, there are gap 200A, so that the structure of the opening and closing of the door of the second cold storage box 110 becomes very simple, can be stably in the second cold storage box 110 Cold insulation is carried out without labyrinth.

In addition, the inner side of second 201, first 202, the auxiliary transmission plane for filling gap 200A is provided with 185, so that even if there are gap 200A, the action of reagent equipped section 103 can also become smooth, can carry out more stable action.

Moreover, second 201, first 202 are made of 2 fan doors of double door, so as to improve the second cold storage box 110 Seal, can further improve the keeping state of the reagent bottle 10 in the second cold storage box 110.

In addition, there is the connecting rod 208 for linking 2 fan doors, so that second 201 and first for second 201, first 202 The on-off action of door 202 need not be carried out independently, action can be opened and closed with simpler structure.

Moreover, there is cover first 202 when closed the 3rd 209 at second 201, so as to further improve Leak tightness in second cold storage box 110.

In addition, the installed in front in reagent equipped section 103 has multiple 3rd rollers 302, multiple rollers (second is provided with right side Front roller 301A, the second rear roller 301B) so that action can be more stably opened and closed in the shutter door of the second cold storage box 110.

In addition, the present invention is not limited to above-mentioned embodiment, moreover it is possible to carry out carry out various modifications, application.Above-mentioned reality The mode of applying is the detailed description for for the ease of understanding illustrating the present invention and carrying out, illustrated the present invention is not limited to include The structured embodiment of institute.

For example, grasping mechanism 106, the opening and closing cover board 113 of reagent disc 9 and reagent probe attract in the present embodiment Mouth 111 is configured on straight line, but as long as reagent probe 7a, 8a, in actionable scope, the configuration of reagent probe suction port 111 can By be not limited to it is linear in a manner of.

In addition, in the present embodiment, to there is the situation of 1 pin 105 to illustrate, but the lid as reagent bottle 10 In the case that 112 have at 2, it is configured to：2 pins 105 are installed with the interval in the hole of the lid 112 of reagent bottle 10, what is most started In action, reagent bottle uncap bolt mechanism 104 down maneuver in the simultaneously perforate of lid 112 at 2.In addition, with pin 105 2 pin rinse baths 108 of interval setting, pin drying mouth 109.Thus, can be carried out with the up and down action of 1 time respectively dry from cleaning to Untill dry, therefore it can shorten and move into the time.

In addition, in the present embodiment, the action specification for bolt mechanism 104 of uncapping on grasping mechanism 106, reagent bottle profit The action of above-below direction is carried out with upper and lower driving motor, the action of left and right directions is carried out using horizontal drive motor 131, if but chasing after Add motor in the front-back direction so as to carry out the action in 3 directions, then the reagent bottle 10 that can be arranged at reagent equipped section 103 is set Putting quantity can also increase.

In addition, in the length of second 201 and first 202, second 201 is set to longer shape, but the length of door According in the scope produced by the spinning movement of door the situation such as arrangement components optimal length, ratio are set.Moreover, It is illustrated on the door with 2 segmentations, even if 1 fan door can also meet identical performance, the structure of connecting rod 208 is in this case not required Part.

In addition, in the present note, to have used the example of the first roller 300 of 4 reagent equipped sections 103 to be illustrated, But the use number of the first roller 300 will be according to the total length of reagent equipped section 103, width, the second cold storage box 110 and reagent carrying on mechanism Gap 200A, 200B of transmission plane 182, are set to the structure as optimum condition, do not limit especially.

In addition, in the present embodiment, show the example for the top that the second cold storage box 110 is arranged to reagent disc 9, but The position of second cold storage box 110 is not limited to top.For example, it is also possible to it is arranged at the side of reagent disc.But by being arranged on The space of device can further be saved.

Label declaration

1 reaction tray

2 reaction vessels

3 wiper mechanisms

4 spectrophotometers

4a light sources

5th, 6 rabbling mechanism

7th, 8 reagent distributor gear

7a, 8a reagent probe

9 reagent discs

10 reagent bottles

10a labels

11 sample distributor gears

11a sample probes

13 rinse baths

15 sample containers

16 stents

17 sample transport mechanisms

18 reagent syringes

19 sample syringes

20 flushing pumps

21 controllers

30th, 31 rabbling mechanism rinse bath

32 sample distributor gear rinse baths

33 reagent distributor gear rinse baths

100 automated loading mechanism

101 reagent transport mechanisms (reagent transport unit)

102 reagent carrying on mechanism

103 reagent equipped sections

103A main bodys

103B protuberances

104 reagent bottles are uncapped bolt mechanism

105 pins

106 grasping mechanisms (crawl section)

108 pin rinse baths

109 pins dry mouth

110 second cold storage boxes (reagent cold storage box)

110A fixed parts

111 reagent probe suction ports

112 lids

113 opening and closing cover boards

114 bottles of direction detection sensors

115 RFID sensors

131 horizontal drive motors

180 reagent carrying on mechanism motors

181 reagent carrying on mechanism conveyer belts

181A, 181B pulley

182 reagent carrying on mechanism transmission planes

182A transmission planes

183 line slideways

184 maintaining parts

185 auxiliary transmission planes

200A, 200B gap

201 second

202 first

203 door lock holes

204 door lock mechanisms

204A is inserted into rod

204B springs

204C inclined plane parts

204D flat parts

205 hook rollers

206 door lock rollers

207 springs

208 connecting rods (linkage)

209 the 3rd

300 first rollers

The second fronts of 301A roller

The second rears of 301B roller

302 the 3rd rollers

303 gate stop grooves.

Claims (12)

1. a kind of automatic analysing apparatus, is injected separately into sample and reagent in reaction vessel, make sample and reagent reacting, and to this Liquid after reaction is measured, which is characterized in that, including：

Reagent disc, it takes care of the reagent bottle for having stored the reagent；

Reagent equipped section, it is used for when moving into the reagent bottle to the automatic analysing apparatus, sets multiple examinations Agent bottle；And

Reagent cold storage box, it carries out the reagent bottle for being arranged at the reagent equipped section together with the reagent equipped section Cold insulation,

The reagent cold storage box has shutter door, it is opened and closed with the disengaging action of the reagent equipped section, for supplying The disengaging of the reagent equipped section.

2. automatic analysing apparatus as claimed in claim 1, it is characterised in that

The shutter door is contacted by being arranged at the roller of the reagent equipped section, so that with the reagent equipped section Disengaging action is opened and closed.

3. automatic analysing apparatus as claimed in claim 1, it is characterised in that

Locking mechanism is further included, when it will be left in the reagent equipped section to the outside of the reagent cold storage box, is opened described Close and locked so that the shutter door is not closed.

4. automatic analysing apparatus as claimed in claim 3, it is characterised in that

The locking mechanism includes the door lock hole for being arranged at the outside of the shutter door, the door lock for being fixed on the reagent cold storage box Mechanism and the door lock roller moved back and forth together with the reagent equipped section,

When the shutter door is opened, using the door lock roller, the door lock mechanism is inserted into the door lock hole, so as to prevent The shutter door is closed.

5. automatic analysing apparatus as claimed in claim 1, it is characterised in that

Reagent carrying on mechanism is further included, it has：Drive the driving motor of the reagent equipped section, be linked to the driving motor Conveyer belt and the holding member that links the conveyer belt and the reagent equipped section.

6. automatic analysing apparatus as claimed in claim 1, it is characterised in that

The reagent cold storage box has the spring that the shutter door is pulled to main body side all the time.

7. automatic analysing apparatus as claimed in claim 1, it is characterised in that

Transmission line is also equipped with, it, which is used to the reagent bottle is arranged at the reagent in operating personnel for the reagent equipped section, takes Moved between the setting position in load portion and the reagent cold storage box,

There are gap between the transmission plane of the reagent equipped section in the transmission line and the reagent cold storage box.

8. automatic analysing apparatus as claimed in claim 7, it is characterised in that

In the inner side of the shutter door, the auxiliary transmission plane for filling the gap is provided with.

9. automatic analysing apparatus as claimed in claim 1, it is characterised in that

The shutter door is made of 2 fan doors of double door.

10. automatic analysing apparatus as claimed in claim 9, it is characterised in that

The shutter door has the linkage for linking 2 fan doors.

11. automatic analysing apparatus as claimed in claim 9, it is characterised in that

Side in 2 fan doors of the shutter door has to be covered to the cover plate-door of another Yishanmen when closed.

12. automatic analysing apparatus as claimed in claim 2, it is characterised in that

Multiple rollers are installed in the reagent equipped section.