CN107921063A - 用于采用登革病毒与树突细胞的联合疗法的组合物及方法 - Google Patents

用于采用登革病毒与树突细胞的联合疗法的组合物及方法 Download PDF

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CN107921063A
CN107921063A CN201680050897.6A CN201680050897A CN107921063A CN 107921063 A CN107921063 A CN 107921063A CN 201680050897 A CN201680050897 A CN 201680050897A CN 107921063 A CN107921063 A CN 107921063A
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cancer
subject
cells
dengue virus
tumor
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布鲁斯·W·里戴
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Universal Leyva Immunology Oncology Co
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Universal Leyva Immunology Oncology Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/19—Dendritic cells
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    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/428—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
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    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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    • C12N2770/24171—Demonstrated in vivo effect
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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CN201680050897.6A 2015-07-02 2016-07-01 用于采用登革病毒与树突细胞的联合疗法的组合物及方法 Pending CN107921063A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562231351P 2015-07-02 2015-07-02
US62/231,351 2015-07-02
PCT/US2016/040787 WO2017004567A1 (en) 2015-07-02 2016-07-01 Compositions and methods for combination therapy with dengue virus and dendritic cells

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CN107921063A true CN107921063A (zh) 2018-04-17

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Country Link
US (6) US9730989B2 (https=)
EP (1) EP3316897A4 (https=)
JP (2) JP2018522880A (https=)
CN (1) CN107921063A (https=)
CA (1) CA2991212A1 (https=)
DE (1) DE202016008300U1 (https=)
MX (1) MX2018000052A (https=)
WO (1) WO2017004567A1 (https=)

Families Citing this family (6)

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CN107921063A (zh) 2015-07-02 2018-04-17 普莱瓦克斯免疫肿瘤学公司 用于采用登革病毒与树突细胞的联合疗法的组合物及方法
CN108291205A (zh) 2015-09-26 2018-07-17 普莱瓦克斯免疫肿瘤学公司 用于产生树突细胞的组合物和方法
JP2020500847A (ja) * 2016-11-16 2020-01-16 プライムヴァックス イミュノ−オンコロジー，インク． 癌の処置のための併用免疫療法
EP3565567A4 (en) * 2017-01-04 2020-07-29 Primevax Immuno-Oncology, Inc. COMPOSITIONS AND METHODS OF THERAPY WITH DENGUE VIRUS
CA3067164A1 (en) * 2017-06-12 2018-12-20 Washington University Zika virus strains for treatment of glioblastoma
KR20200023375A (ko) * 2017-06-15 2020-03-04 프라임벡스 이뮤노-온콜로지, 인크. 뎅기 바이러스 및 수지상 세포를 이용하는 암 요법을 위한 조성물 및 방법

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US10357553B2 (en) 2019-07-23
EP3316897A4 (en) 2019-03-13
US20210187086A1 (en) 2021-06-24
US20190046622A1 (en) 2019-02-14
WO2017004567A1 (en) 2017-01-05
US20180050098A1 (en) 2018-02-22
JP2018522880A (ja) 2018-08-16
US9730989B2 (en) 2017-08-15
US10159727B2 (en) 2018-12-25
DE202016008300U1 (de) 2017-07-14
MX2018000052A (es) 2018-05-11
US20170304422A1 (en) 2017-10-26
US20190247479A1 (en) 2019-08-15
JP2021176862A (ja) 2021-11-11
CA2991212A1 (en) 2017-01-05
US20170000868A1 (en) 2017-01-05
EP3316897A1 (en) 2018-05-09
US10946080B2 (en) 2021-03-16
US9849167B2 (en) 2017-12-26

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Application publication date: 20180417