CN107913338A - A kind of medicine for treating burn and scald ulcer and preparation method thereof - Google Patents
A kind of medicine for treating burn and scald ulcer and preparation method thereof Download PDFInfo
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- CN107913338A CN107913338A CN201810020008.2A CN201810020008A CN107913338A CN 107913338 A CN107913338 A CN 107913338A CN 201810020008 A CN201810020008 A CN 201810020008A CN 107913338 A CN107913338 A CN 107913338A
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- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K2236/30—Extraction of the material
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- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention discloses a kind of medicine for treating burn and scald ulcer, the medicine includes the raw material of following mass fraction：15 25 parts of rheum officinale, 8 15 parts of dragon's blood, 40 50 parts of the coptis, 10 20 parts of frankincense, 10 20 parts of myrrh, 10 15 parts of catechu, 48 parts of pearl, 10 16 parts of calcined gypsum, 48 parts of borneol, 8 14 parts of borax, 8 15 parts of the root of Dahurain angelica, 700 800 parts of vaseline, 45 55 parts of lanolin, 8 15 parts of nipagin ethylester.The medicine of the treatment burn and scald ulcer of the present invention, pasty masses are made and are applied to affected part by vaseline, lanolin heating fusing, energy is clearing heat and detoxicating, invigorates blood circulation, restrains, sterilizing, detumescence and promoting granulation, especially to I II III degree burn and scald, it recovers fast, infect that small, scar is few, there is disinfection, sterilization prevention trauma surface infestation to skin ulcer and skin infection.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of medicine for treating burn and scald ulcer and preparation method thereof.
Background technology
Burn and scald is the damage caused by high-temp solid, liquid or steam etc., is surgical common disease, is that fiery poison is to suffer from, by
In the effect of heat-flash, human body is encroached on, then meat is rotten for excess heat, so that skin and flesh rots, bacterium is taken advantage of a weak point, and damages human righteousness.Burn and scald
Tissue space and the surface of a wound are penetrated into the capillary permeability increase of traumatic part position, blood vessel dilatation, a large amount of blood plasma sample liquid body autoblood circulations.
Burn and scald causes partial trauma illness, and epidermal damage is mishandling, easily causes toxaemia, septicaemia.The traditional Chinese medical science thinks such
Disease is more because heat toxin is pented up, and fiery poison enters blood, and heat stops up blood stasis, and blood slough, which loses, to be formed, clinically it is more from clearing heat and cooling blood, detoxicating and resolving a mass,
Detumescence and apocenosis, promoting granulation and wound healing etc. are seted forth one's views, and are treated and are relieved the pain with anti-inflammation and sterilization, detumescence, restrain myogenic, prevent infection for principle.
Scald is generally divided into 4 grades, is respectively I degree of scald, rubefaction, do not play blister, and dry tack free, after 2-3 days, is scalded
The desquamation of skin, can fully recover preventing from scar for 3-5 days, and necrosis is only limited to epidermis shallow-layer, if the skin injury of seashore sunbath is I
Degree scald.Light degree Ⅱ scald is daily most common, its Damage length reaches the basal cell layer of epidermis and the shallow-layer of corium, due to
Capillary permeability increase, exudate accumulate in and wherein form water bag under epidermis, and the surface of a wound is red and swollen, plays blister, excoriation, pain
Pain is acutely；Deep II degree of scald, injures epidermis, high dermis and partial skin subsidiary body, and original organization disappears at involvement,
Generation coagulation necrosis, slough, which covers, hinders face, since slough is thicker red into crust, the easy avulsion of skin epidermis, substrate
White alternate, hypalgesia, healing leave scar；If trauma surface infestation suppurates, III degree of scald, III degree of scald skin holostrome can be become
And its accessory structure is completely downright bad, some even injures subcutaneous fat, muscle and bone, has thus damaged cell and basic group
Knit, kinematic system local be in yellow-gray, dry even to form incrustation, after the small person of area needs slough to come off or perform the operation and remove
Slowly growth forms scar, and larger area needs skin grafting.
In addition, clinically all kinds of body surface ulcers, for example, injury by sword or axe, crush injury, bumper injury, the ulcer caused by burn and scald,
After carbuncle, subcutaneous ulcer, sore, scabies ulceration, the symptom such as postoperative wound protracted course of disease.
Traditional medicine is varied, and the effect difference for the treatment of is larger.In general, it is existing treatment burn and scald with
And the effect of the drug therapy of ulcer is not notable.And the manufacture cost of medicine is higher, drug ingedient is more complicated.
The content of the invention
It is an object of the invention to provide a kind of medicine for treating burn and scald ulcer, to solve existing drug therapy effect
The defects of fruit is not notable, and medicine manufacture is of high cost.
To achieve the above object, the present invention provides a kind of medicine for treating burn and scald ulcer, and the medicine includes following matter
Measure the raw material of number：15-25 parts of rheum officinale, 8-15 parts of dragon's blood, 40-50 parts of the coptis, 10-20 parts of frankincense, 10-20 parts of myrrh, catechu
10-15 parts, 4-8 parts of pearl, 10-16 parts of calcined gypsum, 4-8 parts of borneol, 8-14 parts of borax, 8-15 parts of the root of Dahurain angelica, vaseline 700-800
Part, 45-55 parts of lanolin, 8-15 parts of nipagin ethylester.
In one embodiment of the present of invention, the medicine includes the raw material of following mass fraction：18-24 parts of rheum officinale, dragon's blood
9-14 parts, 41-49 parts of the coptis, 11-19 parts of frankincense, 11-19 parts of myrrh, 11-14 parts of catechu, 5-9 parts of pearl, calcined gypsum 11-17
Part, 5-9 parts of borneol, 9-15 parts of borax, 9-16 parts of the root of Dahurain angelica, 710-790 parts of vaseline, 46-54 parts of lanolin, nipagin ethylester 9-
14 parts.
In one embodiment of the present of invention, the medicine includes the raw material of following mass fraction：20 parts of rheum officinale, dragon's blood 10
It is part, 45 parts of the coptis, 15 parts of frankincense, 15 parts of myrrh, 12 parts of catechu, 8 parts of pearl, 15 parts of calcined gypsum, 7 parts of borneol, 10 parts of borax, white
12 parts of the root of Dahurian angelica, 750 parts of vaseline, 50 parts of lanolin, 12 parts of nipagin ethylester.
The present invention provides a kind of pharmaceutical methods for preparing treatment burn and scald ulcer described above, it comprises the following steps：
Step A：Rheum officinale, dragon's blood, the coptis, frankincense, myrrh, catechu, pearl, calcined gypsum, borneol, boron are taken according to said ratio
Sand, the root of Dahurain angelica, vaseline, lanolin, nipagin ethylester；
Step B：The coptis is crushed to 20-28 mesh, when addition sulfuric acid solution dipping 20-30 is small, obtains coptis powder leaching
Stain liquid；
Step C：Add lime point to adjust pH value the maceration extract to be 8-9, the maceration extract is added the static 3-10 of sodium chloride
Hour, filter, 100-130 mesh sieves are crossed after leaching thing dry, pulverize, obtain coptis extract powder；
Step D：The dragon's blood, the coptis, frankincense, myrrh, catechu, pearl, calcined gypsum, borneol, borax, the root of Dahurain angelica are crushed to
Fine powder, crosses 120 mesh sieves by the fine powder, obtains mix powder；
Step E：The vaseline, lanolin heating and melting are formed into mixed liquor, the mixed liquor and the coptis are carried
Thing powder, mix powder and the mixed liquor is taken uniformly to be mixed to get primary mix；
Step F：The primary mix and the nipagin ethylester are mixed, form the medicine for the treatment of burn and scald ulcer.
In one embodiment of the present of invention, the mass concentration of sulfuric acid solution is 0.1-0.5% in the step B.
In one embodiment of the present of invention, in the step C, the mass concentration of sodium chloride is 15-20%.
In one embodiment of the present of invention, in the step D, pearl is prepared by the method for fine grinding.
In the present invention, coptis bitter cold, has heat-clearing and damp-drying drug, lets out the function of fiery removing toxic substances, is the monarch drug in a prescription of we, it is used for throat and swells
Bitterly, burning hot wound of pinkeye, aphtha, carbuncle sore tumefacting virus, eczema, soup etc..Modern medicine thinks that coptis master contains berberine, there is good antibacterial
Antiinflammation.To hemolytic streptococcus, Diplococcus pneumopniae, comma bacillus, bacillus anthracis and staphylococcus aureus all have stronger
Bacteriostasis；There is inhibitory action to shigella dysenteriae, corynebacterium diphtheriae, hay bacillus viridans streptococci.It is clinical to be useful for carbuncle more
Subcutaneous ulcer pyogenic infections, pustule sore, acute eczema, aphthae, children's aphthae in children, the burning hot wound of soup etc..It is aided with calcined gypsum hygroscopic, myogenic, sore,
Hemostasis；Frankincense, myrrh promoting blood circulation and stopping pain, detumescence and promoting granulation, makes the power of monarch drug in a prescription eliminating dampness, disinfection, removing toxic substances stronger, and three tastes are ministerial drug altogether；
In the present invention, catechu hygroscopic myogenic sore, dragon's blood stasis-dispelling and pain-killing, hemostasia and promoting granulation, pearl solution taking poison and growing muscle due adjutant for it；
In the present invention, borneol is except having an inducing resuscitation of having one's ideas straightened out, and outside clearing away heat to and alleviating pain, and fragrance is walked to alter, and has and draws all medicines and guide drugs to illness station it
Work(is to make medicine.
Upper all medicines are tied in the present invention, gather the function of disinfection, sterilization altogether.It is mainly used for burning, scalds, skin is burst
Ulcer, the disinfection of skin infection, sterilization, prevention trauma surface infestation etc..
Clinical typical case：
Case 1：Shao, girl, 8 years old, careless left hand was stretched into boiling hot trotter slaughterhouse when grandmother celebrates one's birthday, anterior cubital facies
Position is burned, and scalding area reaches 5%, and wrist reaches II degree.After the drug therapy 15 days of the present invention, decrustation healing,
And without scar.
Case 2：Certain is applied, man, 45 years old, peasant, accidentally by the electric burn right hand during because of construction, to where applicant after 15 days
Clinic is treated, and skin is burned black, has infected when going to a doctor, and is III degree burn.Through debridement, downright bad crust is cut off, the external application present invention's
Medicine is treated, the neat incrustation of meat life after 15 days, the healing of decrustation in 20 days.Paid a return visit after 1 year, hand function is normal, no scar.
Case 3：Huang, man, 11 years old, causes gunpowder detonation because picking up medicine concentration more than residual big gun and lighting during the Lantern Festival, injures face
Portion, right hand III degree burn, is treated 15 days, decrustation healing, no scar.
Case 4：Mr. Wang, male, 60 years old, peasant, because accidentally by rolling rusting wound face, both hands and right lower extremity thigh, patient's pain
Pain unbearably, is had difficulty in breathing, and the clinic where carrying out applicant when 1 is small after wound is gone to a doctor, and is burnt through making a definite diagnosis facial and left ear for III degree.
Being handled through debridement, anti-infective, Hemorrhagic shock and fluid infusion, the medicine of the treatment burn and scald of the external application present invention is treated, and 3
Pain is greatly reduced after hour, and swelling elimination, forms a scab after 7 days after 3 days, and decrustation in 20 days, recovery from illness in 23 days is gone home, and advises its to pay attention to wound
Protect in face.Paid a return visit after 1 year, skin color recovers normal, no scar.
Case 5：Lee, female, 55 years old, because of careless scalding double lower limb, large area was peeled when undressing, and patient pain cries
Cry, because a people is in, 6 be as a child sent to applicant afterwards where clinic go to a doctor, see its double lower limb exfoliation, exudation it is bright
It is aobvious, it is deep II degree of scald.Cleared up through the surface of a wound, is anti-infective, Hemorrhagic shock and fluid infusion processing, the medicine of the treatment burn and scald of the external application present invention
Thing is treated, using wrapping manage, 3 it is small when after relieve pain, form a scab after a week, decrustation in 25 days, recovery from illness in 30 days is gone home.Returned after 1 year
Visit, skin color is normal, no scar.
The invention has the advantages that：
The medicine of the treatment burn and scald ulcer of the present invention, heats fusing by vaseline, lanolin and pasty masses painting is made
In affected part, energy is clearing heat and detoxicating, invigorates blood circulation, restrains, sterilizing, detumescence and promoting granulation, and especially to I II III degree burn and scald, it recovers soon, to infect
It is small, scar is few, there is disinfection, sterilization prevention trauma surface infestation to skin ulcer and skin infection.
Brief description of the drawings
Fig. 1 is that the drug therapy of the treatment burn and scald ulcer of the present invention burns the photo figure of body patient's difference treatment stage.
Embodiment
Following embodiments are used to illustrate the present invention, but are not limited to the scope of the present invention.
Embodiment 1
The medicine of the treatment burn and scald ulcer of the present embodiment, it includes the raw material of following mass fraction：15 grams of rheum officinale, dragon's blood
8 grams, it is 40 grams of the coptis, 10 grams of frankincense, 10 grams of myrrh, 10 grams of catechu, 4 grams of pearl, 10 grams of calcined gypsum, 4 grams of borneol, 8 grams of borax, white
8 grams of the root of Dahurian angelica, 700 grams of vaseline, 45 grams of lanolin, 8 grams of nipagin ethylester.
Embodiment 2
The medicine of the treatment burn and scald ulcer of the present embodiment, it includes the raw material of following mass fraction：25 grams of rheum officinale, dragon's blood
15 grams, 45 grams of the coptis, 20 grams of frankincense, 12 grams of myrrh, 15 grams of catechu, 8 grams of pearl, 16 grams of calcined gypsum, 8 grams of borneol, 14 grams of borax,
15 grams of the root of Dahurain angelica, 800 grams of vaseline, 55 grams of lanolin, 15 grams of nipagin ethylester.
Embodiment 3
The medicine of the treatment burn and scald ulcer of the present embodiment includes the raw material of following quality：18 grams of rheum officinale, 9 grams of dragon's blood, Huang
41 grams of company, 11 grams of frankincense, 11 grams of myrrh, 11 grams of catechu, 5 grams of pearl, 11 grams of calcined gypsum, 5 grams of borneol, 9 grams of borax, the root of Dahurain angelica 9
Gram, 710 grams of vaseline, 46 grams of lanolin, 9 grams of nipagin ethylester.
Embodiment 4
The medicine of the treatment burn and scald ulcer of the present embodiment, it includes the raw material of following quality：24 grams of rheum officinale, dragon's blood 14
Gram, it is 49 grams of the coptis, 19 grams of frankincense, 19 grams of myrrh, 14 grams of catechu, 9 grams of pearl, 17 grams of calcined gypsum, 9 grams of borneol, 15 grams of borax, white
16 grams of the root of Dahurian angelica, 790 grams of vaseline, 54 grams of lanolin, 14 grams of nipagin ethylester.
Embodiment 5
The medicine of the treatment burn and scald ulcer of the present embodiment, it includes the raw material of following quality：20 grams of rheum officinale, dragon's blood 10
Gram, it is 45 grams of the coptis, 15 grams of frankincense, 15 grams of myrrh, 12 grams of catechu, 8 grams of pearl, 15 grams of calcined gypsum, 7 grams of borneol, 10 grams of borax, white
12 grams of the root of Dahurian angelica, 750 grams of vaseline, 50 grams of lanolin, 12 grams of nipagin ethylester.
Above-described embodiment 1 is as follows to the method for the medicine preparation of embodiment 5：
The pharmaceutical methods for preparing above-mentioned treatment burn and scald ulcer of the present invention, it comprises the following steps：
Step A：Rheum officinale, dragon's blood, the coptis, frankincense, myrrh, catechu, pearl, calcined gypsum, borneol, boron are taken according to said ratio
Sand, the root of Dahurain angelica, vaseline, lanolin, nipagin ethylester；
Step B：The coptis is crushed to 20-28 mesh, when addition sulfuric acid solution dipping 20-30 is small, obtains coptis powder maceration extract
Body, wherein, the mass concentration of sulfuric acid solution is 0.1-0.5%.
Step C：It is 8-9 that maceration extract plus lime point are adjusted pH value, during by maceration extract plus the static 3-10 of sodium chloride small, pumping
Filter, crosses 100-130 mesh sieves after leaching thing dry, pulverize, obtain coptis extract powder, wherein, the mass concentration of sodium chloride
For 15-20%.
Step D：Dragon's blood, the coptis, frankincense, myrrh, catechu, pearl, calcined gypsum, borneol, borax, the root of Dahurain angelica are crushed to carefully
Powder, crosses 120 mesh sieves by fine powder, obtains mix powder；Wherein, pearl is prepared by the method for fine grinding.
Step E：Vaseline, lanolin heating and melting are formed into mixed liquor, by mixed liquor and coptis extract powder, mixed
Thing powder is uniformly mixed to get primary mix with mixed liquor；
Step F：Primary mix and nipagin ethylester are mixed, the medicine for the treatment of burn and scald ulcer is formed, is packaged into
Product medicine.
It is as follows that medicine prepared by the embodiment of the present invention 1 to embodiment 5 carries out clinical test experimental result：
One clinical test results of table：
The medicine of the treatment burn and scald ulcer of the present invention, heats fusing by vaseline, lanolin and pasty masses painting is made
, can be clearing heat and detoxicating in affected part, promoting blood circulation, convergence, sterilization, detumescence and promoting granulation, especially to I II III degree burn and scald, it recovers fast, infection
It is small, scar is few, has disinfection, sterilization prevention trauma surface infestation to skin ulcer and skin infection.
As shown in Figure 1, it is the healing case of the medicine of the treatment burn and scald ulcer of the present invention, when A burns for patient in Fig. 1
Patient burns the photo figure of degree, and B is photo of the medicine for the treatment burn and scald ulcer that patient coats the present invention after 10 days in Fig. 1
Scheme, C is photo figure of the medicine for the treatment burn and scald ulcer that patient coats the present invention after 20 days in Fig. 1.By this present invention's
After drug coat treatment, the wound face resume speed of patient is fast, no hyperplastic scar, and can retain pore on wound face, tool
There is the good effect of recovery of wound face.
Although above with general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to the scope of protection of present invention.
Claims (7)
1. a kind of medicine for treating burn and scald ulcer, it is characterised in that the medicine includes the raw material of following mass fraction：Rheum officinale
15-25 parts, 8-15 parts of dragon's blood, 40-50 parts of the coptis, 10-20 parts of frankincense, 10-20 parts of myrrh, 10-15 parts of catechu, 4-8 parts of pearl,
10-16 parts of calcined gypsum, 4-8 parts of borneol, 8-14 parts of borax, 8-15 parts of the root of Dahurain angelica, 700-800 parts of vaseline, 45-55 parts of lanolin,
8-15 parts of nipagin ethylester.
2. the medicine for the treatment of burn and scald ulcer according to claim 1, it is characterised in that
The medicine includes the raw material of following mass fraction：18-24 parts of rheum officinale, 9-14 parts of dragon's blood, 41-49 parts of the coptis, frankincense 11-
19 parts, it is 11-19 parts of myrrh, 11-14 parts of catechu, 5-9 parts of pearl, 11-17 parts of calcined gypsum, 5-9 parts of borneol, 9-15 parts of borax, white
9-16 parts of the root of Dahurian angelica, 710-790 parts of vaseline, 46-54 parts of lanolin, 9-14 parts of nipagin ethylester.
3. the medicine for the treatment of burn and scald ulcer according to claim 1, it is characterised in that
The medicine includes the raw material of following mass fraction：20 parts of rheum officinale, 10 parts of dragon's blood, 45 parts of the coptis, 15 parts of frankincense, myrrh 15
Part, 12 parts of catechu, 8 parts of pearl, 15 parts of calcined gypsum, 7 parts of borneol, 10 parts of borax, 12 parts of the root of Dahurain angelica, 750 parts of vaseline, lanolin 50
Part, 12 parts of nipagin ethylester.
A kind of 4. pharmaceutical methods for preparing any one of them of the claims 1 to 3 treatment burn and scald ulcer, it is characterised in that
Comprise the following steps：
Step A：According to said ratio take rheum officinale, dragon's blood, the coptis, frankincense, myrrh, catechu, pearl, calcined gypsum, borneol, borax,
The root of Dahurain angelica, vaseline, lanolin, nipagin ethylester；
Step B：The coptis is crushed to 20-28 mesh, when addition sulfuric acid solution dipping 20-30 is small, obtains coptis powder maceration extract
Body；
Step C：It is 8-9 to add lime point to adjust pH value the maceration extract, when adding the static 3-10 of sodium chloride small the maceration extract,
Filter, 100-130 mesh sieves are crossed after leaching thing dry, pulverize, obtain coptis extract powder；
Step D：The dragon's blood, the coptis, frankincense, myrrh, catechu, pearl, calcined gypsum, borneol, borax, the root of Dahurain angelica are crushed to carefully
Powder, crosses 120 mesh sieves by the fine powder, obtains mix powder；
Step E：The vaseline, lanolin heating and melting are formed into mixed liquor, by the mixed liquor and the coptis extract
Powder, mix powder and the mixed liquor are uniformly mixed to get primary mix；
Step F：The primary mix and the nipagin ethylester are mixed, the medicine for the treatment of burn and scald ulcer is made.
5. the pharmaceutical methods for the treatment of burn and scald ulcer according to claim 1, it is characterised in that
The mass concentration of sulfuric acid solution is 0.1-0.5% in the step B.
6. the pharmaceutical methods for the treatment of burn and scald ulcer according to claim 1, it is characterised in that
In the step C, the mass concentration of sodium chloride is 15-20%.
7. the pharmaceutical methods for the treatment of burn and scald ulcer according to claim 1, it is characterised in that
In the step D, pearl is prepared by the method for fine grinding.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112190650A (en) * | 2020-11-26 | 2021-01-08 | 董亚利 | Traditional Chinese medicine composition and medicament for treating skin wounds |
| CN113694108A (en) * | 2021-10-11 | 2021-11-26 | 郭成才 | Ointment for treating burn |
| CN115154532A (en) * | 2022-08-25 | 2022-10-11 | 湖南中医药大学第一附属医院((中医临床研究所)) | A Chinese medicinal preparation with broad-spectrum antibacterial effect for treating burn and scald, and its preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1280000A (en) * | 1999-07-12 | 2001-01-17 | 于铭昭 | External use chinese herbal medicine for curing burn and scald and its using method |
| CN102552480A (en) * | 2012-02-21 | 2012-07-11 | 白亚军 | Ointment for treating burn and scald and preparation method thereof |
-
2018
- 2018-01-09 CN CN201810020008.2A patent/CN107913338A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1280000A (en) * | 1999-07-12 | 2001-01-17 | 于铭昭 | External use chinese herbal medicine for curing burn and scald and its using method |
| CN102552480A (en) * | 2012-02-21 | 2012-07-11 | 白亚军 | Ointment for treating burn and scald and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 刘新等主编: "《天然药物化学》", 31 August 2007, 第四军医大学出版社 * |
| 常树春等: "中药烧烫灵的制备及疗效观察", 《中国医院药学杂志》 * |
| 张晶主编: "《偏方治大病大全》", 31 July 2016, 中国古籍出版社 * |
| 易磊编著: "《妙用本草良方》", 31 January 2006, 中医古籍出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112190650A (en) * | 2020-11-26 | 2021-01-08 | 董亚利 | Traditional Chinese medicine composition and medicament for treating skin wounds |
| CN113694108A (en) * | 2021-10-11 | 2021-11-26 | 郭成才 | Ointment for treating burn |
| CN115154532A (en) * | 2022-08-25 | 2022-10-11 | 湖南中医药大学第一附属医院((中医临床研究所)) | A Chinese medicinal preparation with broad-spectrum antibacterial effect for treating burn and scald, and its preparation method |
| CN115154532B (en) * | 2022-08-25 | 2023-04-25 | 湖南中医药大学第一附属医院((中医临床研究所)) | A Chinese medicinal preparation with broad-spectrum antibacterial effect for treating burn and scald, and its preparation method |
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Application publication date: 20180417 |